association	dataset	threshold value	standardized value
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.848519
Wing	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.829
Perturb_7182_KD_MED26_SRP164752	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.89497
trans-Golgi network	GO Cellular Component Annotations 2023	1.0	null
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1987
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882547
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
F8	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-UPK5-0426-SM-3GAEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82797
ROS50	DepMap CRISPR Gene Dependency	1.0	3.19479
ZFX-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DDX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52068
MSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74546
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_11438_KO_RB1/TP53_SRP253428	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.76561
F13A1	Pathway Commons Protein-Protein Interactions	1.0	null
Sodium/calcium exchanger membrane region	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1269
Perturb_1679_KO_Nox4_SRP356837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.0128
Ocular albinism 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.117
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE130383_1_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88569
be11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.101715
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.604
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.36814
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9627
496100636_FWM_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.09894
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11201
divalent inorganic cation transport	GO Biological Process Annotations 2015	1.0	null
TRIM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05259
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	0.93624
transport	GO Biological Process Annotations 2015	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.707
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27906
Nodulus (X)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78156
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24879
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986315
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12289
Pelvic fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.579
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70W-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Hair follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.848
Anterior olfactory nucleus, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64652
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50753
asian	GeneRIF Biological Term Annotations	1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04168
background	GeneRIF Biological Term Annotations	1.0	null
inferior frontal gyrus, triangular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40282
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07884
Perturb_16082_KO_Hoxa9_SRP090515	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.0387
all	GeneRIF Biological Term Annotations	1.0	null
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19234
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8828
OTUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63499
Brain Lower Grade Glioma_LGG_TCGA-DU-A76K-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TFAP2A-17053090-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_2600_KD_HDAC2_SRP149375	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.28998
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fastigial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22112
STAT3	ENCODE Transcription Factor Targets	1.0	null
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41735
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.922619
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.441312
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A24D-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12687_KD_E2F1_SRP068942	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.37518
Congenital nystagmus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.982
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.829696
Perturb_9412_KD_Pcbp1/Platr18_SRP251371	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.07255
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFG7-1126-SM-4LMK3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_7354_OE_TUT7_SRP120600	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.57292
calcium:sodium antiporter activity	GO Molecular Function Annotations 2025	1.0	null
496100404_PCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11728
ventrolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.841187
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975174
Perturb_2988_KO_KMT2C_SRP108473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.83979
Perturb_16922_OE_miR26a_SRP216065	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.204
RD	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02292
GSE148066,GSE157787_8_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3478
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62969
Perturb_2019_KO_Parp1_SRP243891	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.75566
BLOC-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.9
GSE169205_0_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_101_KD_LATS_SRP353750	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.1675
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.92823
GTEX-S4UY-0926-SM-4AD6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_9291_KO_Parp1_SRP254965	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.72124
Endolysosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.508
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930477
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041509
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1434
BCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58699
Entorhinal area, medial part, dorsal zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08864
Perturb_17_OE_Carhsp1_SRP217699	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.74342
ZNF148	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97339
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17478
MYO5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78259
Perturb_7490_KD_SIN3B_SRP173465	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.6339
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.46309
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.84633
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70T-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33491
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.436
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10356
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49637
Gas bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.853
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_14321_KD_CD95L_SRP111532	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.4317
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34157
ocular albinism	MGI Mouse Phenotype Associations 2023	1.0	null
GSE193157_0_v_1_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF490	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33733
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
MND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53437
Perturb_5541_KO|KD_Fh1|Foxa2_ERP138019	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.0569
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.327205
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Perturb_15611_KO_Nampt_SRP065603	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.5151
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994814
Perturb_15587_KD_EP300_SRP355992	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.73987
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
KRTCAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3673
Melanocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.684
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21533
Sapling	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.014
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46F-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13240_KO_Lamtor1_SRP126727	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.43401
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35499
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Retinal pigment epithelium cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.983
Perturb_15559_KO_SLFN11_SRP327912	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.3159
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Lung squamous cell carcinoma_LUSC_TCGA-85-7696-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased prepulse inhibition	MGI Mouse Phenotype Associations 2023	1.0	null
SIKE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67664
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_14760_KD_LATS1/LATS2_SRP345234	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.96618
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r4 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71247
superficial stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04405
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26817
AR	ChEA Transcription Factor Targets	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
HADHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10529
Perturb_13854_KD_SOX9_SRP201900	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.6851
Perturb_13980_KD_Ago2_ERP133202	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Incisor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.117
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.707
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93242
Degeneration of macula and posterior pole	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
EPLC-272H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_4714_KO_Hnrnpu/Trp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Chediak-Higashi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.405
Eccrine sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.347
FLNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73544
skin	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29Q-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMUC16	DepMap CRISPR Gene Dependency	1.0	9.35337
CHTF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47092
Perturb_6551_KO_Ahsg_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.75633
Feather bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.517
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
ARHGAP11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78962
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135350_3_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_2776_KD_YBX1_SRP072302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.87861
Perturb_2779_OE_ACF7_SRP109301	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.21622
Larva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.584
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.022
DEOC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28929
Integumentary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.035
AKT1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97089
Orbital area, lateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05717
Perturb_5228_KO_Dnmt1/Dnmt3a/Dnmt3b_SRP194961	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.88905
Perturb_17641_OE_YAP_SRP298391	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.16159
PCID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99115
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.54299
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_6620_KO_NEUROD1_SRP388830	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.54252
GSE239578_0_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885728
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_3487_KO_Kctd13_ERP112326	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.8223
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08054
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06368
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08401
Diabetes Mellitus, Type 2	CTD Gene-Disease Associations	1.0	1.31837
Intracellular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.332
integument phenotype	MPO Gene-Phenotype Associations	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCIH1755	DepMap CRISPR Gene Dependency	1.0	2.93851
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4308
diversity	GeneRIF Biological Term Annotations	1.0	null
Perturb_5867_KD_Cpsf6_SRP336206	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.6054
496100569_TCx_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26917
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07273
Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4489_KO_Rnu11/Trp53_SRP309496	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.78003
CLPTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39108
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_13232_OE_Rnaseh1_SRP056871	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.39886
Hereditary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
GSE196104,GSE196106_3_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.852169
GSE254517_2_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE249544,GSE249637_9_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
RPMI8226	CCLE Cell Line Gene CNV Profiles	1.0	1.66261
Perturb_16939_OE_Prkag1_SRP162537	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.49079
Perturb_83_KD_HOXC4|HOXC6_SRP192852	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.69123
CDK7_knockdown_138_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.21842
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01264
Perturb_4566_KD_Setdb1_SRP172038	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.03384
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
LRIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29657
TYMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3351
PMC7431913-Table_1.xls-Sheet1-TablesS1_Gene_clusters_highly_co-expressed_with_MNX1_MNX1	Rummagene Transcription Factor Associations 2026	1.0	null
age-related macular degeneration	GWASdb SNP-Phenotype Associations	1.0	0.808534
Perturb_9696_KO_GPNMB_SRP382180	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.2731
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01882
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.844751
MAP2K1_knockdown_134_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.55309
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.832153
Perturb_14903_KO_PRMT6_SRP125977	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.00941
superficial stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44979
KYSE-270	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ASF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15375
Perturb_11184_KO_Jmjd1c_SRP239229	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.779
Perturb_9459_KO_Srsf3_SRP143519	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.25615
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.88857
calcium, potassium:sodium antiporter activity	GO Molecular Function Annotations 2015	1.0	null
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.165408
west	GeneRIF Biological Term Annotations	1.0	null
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24034
GSE132948,GSE132949_0_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13080_KO_Cry2_SRP091906	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.79473
GSE168807_0_v_8_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
golgi apparatus part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.006855
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GSE217115_2_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cation transport	GO Biological Process Annotations 2015	1.0	null
Perturb_2774_KD_TRIM25_SRP072302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.77027
GNA12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70579
ULK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67725
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.9003
PMC3840000__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Perturb_14947_KD_Parp1_SRP102079	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.11683
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.888736
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.963515
inner SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06445
SLC transporter disorders	Reactome Pathways 2024	1.0	null
colour	GeneRIF Biological Term Annotations	1.0	null
mc1r	GeneRIF Biological Term Annotations	1.0	null
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66
CCNJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.31669
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26441
Perturb_31_KO_Mga_SRP314000	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.35786
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73833
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69187
Lung squamous cell carcinoma_LUSC_TCGA-34-5929-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mammary gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
superficial stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05616
Perturb_15680_KD_Srsf9_SRP313287	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.56098
GSE213588_9_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223008_9_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.65715
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Lung adenocarcinoma_LUAD_TCGA-55-6985-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17339_KO_Plag1_SRP095348	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.18628
NCIH2887	DepMap CRISPR Gene Dependency	1.0	2.48193
Perturb_1111_KD_Creb3l1_SRP255011	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.71765
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03705
PSIP1_Deficiency_GDS2883_633_human_T-cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01035
GSE77178_5_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.910425
Perturb_3013_KO_TLE4_SRP298305	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.15024
Perturb_13212_KO_Lima1_ERP128082	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.74214
Perturb_16671_KO_Zfp36l2_SRP310261	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.8359
PMC2694838-1471-2164-10-241-S2.xls-Sheet1-Regulated_genes_by_ZNF191_knockdown_ZNF24	Rummagene Transcription Factor Associations 2026	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043513
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.997101
Carapace	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.775
P53_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
ROCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28775
abnormality of vision	HPO Gene-Disease Associations	1.0	null
abnormal anterior eye segment morphology	MPO Gene-Phenotype Associations	1.0	null
Perturb_13653_KD_CELSR2_SRP149837	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.0524
organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_5004_KO_Rinf_SRP200002	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.6869
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10804
Perturb_4669_OE_Wdr5/Trp53|Wdr5_SRP324834	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Oculocutaneous albinism	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
CBFA2T3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46331
negative regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
schizophrenia	GAD Gene-Disease Associations	1.0	null
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39615
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898242
GTEX-XOT4-0008-SM-4B664	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
mantle zone of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25992
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.0189
GSE112860_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
eye and adnexa disease	GWASdb SNP-Disease Associations	1.0	0.136631
NSL complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.885
IER3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24723
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MU-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22464
Perturb_4686_KD_Srsf1_SRP059321	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.96179
PROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23181
PRORP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84699
Perturb_4802_KO_Mapk1_ERP004375	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.67033
ERBB3_drugactivation_70_GSE21463	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.79161
Perturb_3910_KO_ARID1A_ERP114370	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.0785
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.982715
Perturb_11167_KO_Tsc1|Pten_SRP156216	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.2234
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Autosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.062
abnormal epidermal pigmentation	MGI Mouse Phenotype Associations 2023	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26526
Perturb_12903_KD_ER_SRP313175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.57844
Epithalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12875
Perturb_6684_KD_SMARCA2_SRP378606	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE77178_2_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112860_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
ARMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67096
Perturb_7153_KD_MOV10_SRP029367	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.48561
retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058024
GSE147943_4_v_6_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal involuntary eye movements	HPO Gene-Disease Associations	1.0	null
LRPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23569
PC3	DepMap CRISPR Gene Dependency	1.0	3.29622
calcium ion transport	GO Biological Process Annotations 2025	1.0	null
CLPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27313
outer CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59513
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976333
CA12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42018
ZNF366	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36973
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839898
Feather calamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.917
Frontal pole, cerebral cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01279
GTEX-WFON-1926-SM-3LK7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982701
abnormal coat/ hair morphology	MPO Gene-Phenotype Associations	1.0	null
Perturb_4256_KD_NCOR2_SRP326059	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.74796
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.714
localized	GeneRIF Biological Term Annotations	1.0	null
GSE213588_8_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.956926
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88286
PMC12032240-41598_2025_99253_MOESM1_ESM.docx-0-Genes_in_AR_inheritance_mode_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29306
cation:cation antiporter activity	GO Molecular Function Annotations 2015	1.0	null
CTTNBP2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0107
Perturb_10852_KO_Smyd3_SRP057101	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.45513
r6 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00695
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.77719
Cell hair	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.696
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01046
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
OAW42	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43789
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.9673
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.49103
divalent metal ion transport	GO Biological Process Annotations 2015	1.0	null
Dorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81019
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20096
Prostate adenocarcinoma_PRAD_TCGA-G9-6362-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40681
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.859833
FGFR3_KD_GDS4454_78_human_RT112	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
BBS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52257
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
CTNNBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69543
sodium ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
monoatomic cation channel activity	GO Molecular Function Annotations 2025	1.0	null
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51368
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PTMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34581
Perturb_8462_KO_IFNLR1_ERP121014	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27173
Perturb_14149_KO_KBTBD4_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
r1 part of vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30243
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.296
CNBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10236
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040683
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.97
monovalent inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
MORC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34197
Angelman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
Perturb_12160_OE_TCF7_SRP144189	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.12411
ZC3H12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19956
SUDHL5	DepMap CRISPR Gene Dependency	1.0	2.83377
abnormal hair shaft melanin granule shape	MGI Mouse Phenotype Associations 2023	1.0	null
KISS1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06481
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72976
Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
postcentral gyrus, right, inferior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.950509
GSE162739_7_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2374_KO_ASXL1_SRP305063	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.53378
Perturb_7408_KD_HNRNPM_SRP010280	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.17306
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
MAP7D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.00905
Nodulus (X), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86566
WDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74242
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
polymorphism	GeneRIF Biological Term Annotations	1.0	null
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.52867
STAT4	ChEA Transcription Factor Targets	1.0	null
calcium, potassium:sodium antiporter activity	GO Molecular Function Annotations 2025	1.0	null
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72936
REC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67806
hermansky-pudlak syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.675112
Perturb_5222_KO_Polr2a_SRP181107	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.90345
Longissimus lumborum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.89
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
POGLUT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26761
Sickle cell disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09569
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07088
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.4809
GSE220600_1_v_2_clpp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cutaneous melanoma or hair colour	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.9
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32131
Prostate adenocarcinoma_PRAD_TCGA-EJ-8472-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59539
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29605
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU761	CCLE Cell Line Gene CNV Profiles	1.0	2.28293
WBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43054
B3GNT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00777
subcallosal cingulate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.935041
Perturb_14161_KD_BZW1/BZW2_SRP316321	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.82832
abnormality of the eye	GWASdb SNP-Phenotype Associations	1.0	0.099439
Perturb_14588_KD_TCF7L1_SRP094619	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.34063
Perturb_7166_KD_circFAM120A_SRP259913	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.54691
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.64031
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051934
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.12872
AKR1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31584
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.2109
Diabetic Nephropathies	HuGE Navigator Gene-Phenotype Associations	1.0	null
Microgametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.811
abnormal iris pigmentation	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_2131_KD_HAPSTR1_SRP377309	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.83267
STX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20183
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.86063
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21241
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01981
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01823
localization	GO Biological Process Annotations 2015	1.0	null
Abnormal Foveal Morphology On Macular Oct	DisGeNET Gene-Phenotype Associations	1.0	null
NKX2-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14555
GTEX-XPVG-1326-SM-4B65P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841054
Bcl11b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.5036
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.958556
Perturb_10400_KD_ASH2L_SRP277215	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.63375
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SPSB1	Hub Proteins Protein-Protein Interactions	1.0	null
CUL4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40648
PPP1R1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08176
Perturb_166_KD_Mir21_SRP361611	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.69093
DMS153	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65851
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
OCUM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.414
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.59434
DUSP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40781
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05141
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
Perturb_14945_KD_Parp1_SRP102079	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.73924
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11681
TFAP2A-17053090-MCF7-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_12738_KD_TCF7L1_SRP094619	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.33199
PHF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31205
HS939T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83877
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85912
increased circulating sodium level	MGI Mouse Phenotype Associations 2023	1.0	null
Autosomal recessive disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
Marfan syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
Lung adenocarcinoma_LUAD_TCGA-64-5774-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_282_KD_IMPDH1_SRP251285	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_7096_KO_Eif2ak3_SRP271084	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.05701
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4335-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sodium/potassium/calcium exchanger 5	InterPro Predicted Protein Domain Annotations	1.0	null
GSE167004_0_v_3_thpo_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
secondary active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_10_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-A47B-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STARD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.96398
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45178
r3 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1144
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15817
calcium ion transmembrane transport	GO Biological Process Annotations 2023	1.0	null
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13785_OE_IL10RB_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.58733
GSE150665,GSE150667_4_v_8_mysm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
embryoday8.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.32595
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.032
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857255
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.868558
Rectum adenocarcinoma_READ_TCGA-AH-6643-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
alters	GeneRIF Biological Term Annotations	1.0	null
Perturb_6108_KO_Mki67_SRP295162	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.11596
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.356606
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.906253
TTLL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81369
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_6179_KO_Mecp2_SRP188207	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.05143
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39142
AICDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9433
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31843
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971491
LAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55486
NEFL	Pathway Commons Protein-Protein Interactions	1.0	null
[skin/hair/eye pigmentation 4, fair/dark skin]	OMIM Gene-Disease Associations	1.0	null
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23748
Perturb_6617_KO_NEUROD1_SRP388830	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.35203
Skin mucus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.799
retinal pigment epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EOMES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39272
Perturb_493_KO_RN7SK_SRP367813	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_13315_KD_Fosl2_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.90467
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19237
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative regulation of cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Perturb_14586_KD_IGF2BP1_SRP291710	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.48709
Medulloblastoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_14201_KD_HNF4A/GATA6_ERP108557	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.4024
Perturb_13197_KO_HDAC3_ERP127280	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.52737
DCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90521
CORL47	DepMap CRISPR Gene Dependency	1.0	3.86096
E2F1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ELF5	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
USP9X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49979
LRRC55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24773
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AD-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.900995
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.875645
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.95288
HMGCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34028
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211226_1_v_0_sirpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hermansky-Pudlak syndrome 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15852
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
divalent inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Albinism, Ocular	DisGeNET Gene-Disease Associations	1.0	null
r4 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01203
ZBED5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7337
common	GeneRIF Biological Term Annotations	1.0	null
COPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21431
PHF8	ENCODE Transcription Factor Targets	1.0	null
Perturb_14599_KD_IGF2BP1_SRP252427	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.46252
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2826
Perturb_8290_KD_PRPF8_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.37498
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00551
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
cation transmembrane transport	GO Biological Process Annotations 2015	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70988
GSE239578_0_v_4_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_2383_OE_ROR2_SRP293436	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.40061
TCF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2323
Perturb_17317_KO_Ddx5_SRP284247	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.90372
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.941456
CCK81	DepMap CRISPR Gene Dependency	1.0	4.6616
COX6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0839
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4341-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_212_KD_AU021063_SRP324142	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.8854
Photoreceptor cell cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.185
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
breast	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.972111
Perturb_6460_KO_EZH2_SRP136292	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.53642
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
periventricular stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71247
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40748
Perturb_2767_KD_CTBP1_SRP072302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.10366
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65831
instances	GeneRIF Biological Term Annotations	1.0	null
PPP1R8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23604
Bpe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.535
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Melanoma	HuGE Navigator Gene-Phenotype Associations	1.0	null
sodium ion transport	GO Biological Process Annotations 2015	1.0	null
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.1722
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_16813_OE_HNF1A/FOXA3/PROX1/SIRT1/PGC1A/AMPK_SRP167105	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.69128
GSE189653,GSE203344_5_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_13776_KD_IFNAR2_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.47743
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.154
Perturb_2348_KD_IRF1_SRP381930	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.70332
where	GeneRIF Biological Term Annotations	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01703
calcium ion transmembrane transport	GO Biological Process Annotations 2025	1.0	null
retinal rod	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.856732
Perturb_13205_KO_Hdac3_ERP123505	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.37743
abnormal anterior uvea morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07797
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4733
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995019
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.261
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03398
JHOS-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.347587
Perturb_14735_KD_ADAR1_SRP250165	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.2291
A1207	CCLE Cell Line Gene CNV Profiles	1.0	1.49297
Lung adenocarcinoma_LUAD_TCGA-64-5778-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01804
Perturb_5394_KD_LIM1_SRP402415	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.4295
skin_5e	HPA Tissue Sample Gene Expression Profiles	1.0	2.1231
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46826
GSE183413_1_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of r4Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01243
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7401461-iovs-61-3-10_s001.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.90168
Foveal hypoplasia 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.007
GSE95685_2_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_11528_KD_ATAC1_SRP109127	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6936-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37891
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_14155_KO_KBTBD4_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inorganic cation transmembrane transport	GO Biological Process Annotations 2025	1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.707
Generalized Hypopigmentation	DisGeNET Gene-Phenotype Associations	1.0	null
trans-golgi network	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Perturb_8919_KD_ARID1A/P300_SRP256204	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.28061
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.983697
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22038
Skin-melanocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.147238
all	GWASdb SNP-Phenotype Associations	1.0	0.048027
NCIH1105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33585
Perturb_13275_KO_Zbtb24_SRP198761	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.33802
CSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25818
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.475
TWNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40519
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29759
abnormal epidermal pigmentation	MPO Gene-Phenotype Associations	1.0	null
Perturb_2389_KD_NSD3_SRP267458	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.39436
b16a	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.651
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.896621
GTEX-QDT8-0326-SM-32PL1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829779
Field CA2, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16998
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21533
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.98895
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869102
GTEX-OXRK-1326-SM-3NB1A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GSE145323,GSE145324_1_v_4_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RWS6-0826-SM-47JXF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Ocular Albinism	DisGeNET Gene-Disease Associations	1.0	null
OCT4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_15615_Mut_Dmd_SRP329695	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.38286
Perturb_5195_KD_SEPHS1_SRP117644	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.66187
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043946
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.35415
Perturb_15399_KD_RUVBL1_SRP361862	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.2711
Perturb_16919_KD_H19_SRP151268	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.86568
medial geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97073
calcium channel activity	GO Molecular Function Annotations 2025	1.0	null
BLOC-3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.721
secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.094452
NCI-H1876	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COR-L32	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_13358_KD_Irf1_SRP234803	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.99807
retinal degeneration	GWASdb SNP-Disease Associations	1.0	0.354206
SORBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
candidate	GeneRIF Biological Term Annotations	1.0	null
reduction	GeneRIF Biological Term Annotations	1.0	null
Reduced Visual Acuity	DisGeNET Gene-Phenotype Associations	1.0	null
albinism	GeneRIF Biological Term Annotations	1.0	null
Perturb_7967_OE|KO_MPL_SRP287959	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.03254
Prostate adenocarcinoma_PRAD_TCGA-VN-A88M-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850295
Prepuce	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.236
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64856
iris hypoplasia	MPO Gene-Phenotype Associations	1.0	null
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.862566
Endosome lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.548
Perturb_2862_Mut_CTNNB1_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.12648
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940029
Perturb_2764_KD_FOXA1_SRP077334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.4149
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.954437
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03955
PTP4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26814
Perturb_2390_KD_HIF1A/HIF2A_SRP308699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	13.9423
MBL2	Pathway Commons Protein-Protein Interactions	1.0	null
CTSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.50148
age related macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.184128
VEGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27564
layer 3 of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04769
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.87998
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.885012
melanophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.9118
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29228
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.984132
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE160817_0_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
PSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70945
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
more	GeneRIF Biological Term Annotations	1.0	null
Perturb_8238_KD_RBM25_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.84131
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L6-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMH-2	COSMIC Cell Line Gene CNV Profiles	-1.0	-5.12655
Perturb_11799_KO_Fads1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.72877
medial (main) part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.71406
Perturb_5819_KD_Pcbp1_SRP324137	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.59187
BNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93901
Perturb_409_KO_IRE1_SRP353826	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.22005
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11473
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17098
Metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
496100440_FWM_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01383
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
integumentary system disease	GWASdb SNP-Disease Associations	1.0	0.377193
kidney	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
aortic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.127379
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.9428
SFN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12683
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04303
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.20086
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.74589
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22464
Perturb_13921_KO_PPARGC1A_SRP314654	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.56075
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0077
AR-22383394-PROSTATE_CANCER-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_4524_KO_Phc3_ERP112796	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.58946
Perturb_9299_KO_Parp1_SRP254965	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.83619
Medial geniculate complex, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11612
GSE184902_3_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
indicating	GeneRIF Biological Term Annotations	1.0	null
GSE145311_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
CLIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35077
parahippocampal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.849388
Foveal hypoplasia 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.327
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
WM-266-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27274
Mandibular incisor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25992
CHRNA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97765
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38244
Monogenic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
abundance	GeneRIF Biological Term Annotations	1.0	null
Perturb_11424_KD_KIF4A_SRP324259	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.62535
Congenital stationary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
LCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45574
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02159
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_7619_OE_OspC1_SRP368098	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.51878
megacolon	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.720461
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.997268
Perturb_1006_KO_Bcl9l/Bcl9_SRP045828	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.52043
trans-Golgi network	GO Cellular Component Annotations 2025	1.0	null
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49526
KINGS1	DepMap CRISPR Gene Dependency	1.0	3.43938
PMC11263707-41419_2024_6896_MOESM6_ESM.pdf-67-SIX3-AS1_SIX3	Rummagene Transcription Factor Associations 2026	1.0	null
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7563
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.37172
inorganic cation transmembrane transport	GO Biological Process Annotations 2023	1.0	null
GTEX-XQ8I-1826-SM-4BOOJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845172
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.824646
Iridosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.323
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37262
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-RWSA-0926-SM-47JXW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01263
Skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.393
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
C99	DepMap CRISPR Gene Dependency	1.0	2.32952
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Perturb_4715_KO_Hnrnpu/Trp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
JUND_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal ocular fundus morphology	MPO Gene-Phenotype Associations	1.0	null
F10	Pathway Commons Protein-Protein Interactions	1.0	null
single-organism transport	GO Biological Process Annotations 2015	1.0	null
Rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
visual impairment	HPO Gene-Disease Associations	1.0	null
Perturb_805_KO_Trim28_ERP125317	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.25918
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.4899
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_3970_Mut_BRAF_SRP258593	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.37128
TAL1_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dermal papilla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.758
calcium ion transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
Perturb_14764_KD_LATS1/LATS2_SRP345234	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.99271
FAM43A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37521
Anal fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.365
SKMEL30	DepMap CRISPR Gene Dependency	1.0	3.83781
Pigmentation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.402
GSE178255_2_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMARCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08353
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.334
abnormality of the posterior segment of the eye	GWASdb SNP-Phenotype Associations	1.0	0.217679
Macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5107-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal ocular fundus morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GSE148066,GSE157787_9_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_15630_KD_Ctnnb1_SRP130920	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.82953
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4811-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1261
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.8875
Lung squamous cell carcinoma_LUSC_TCGA-77-7139-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.828183
Perturb_9684_KD_POU3F2_SRP242009	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.23741
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.501
GSE147662_2_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.934901
Perturb_7084_KO_Perk_SRP309948	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.31295
NDUFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72746
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
Ptf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.846
KPNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50611
EW22	DepMap CRISPR Gene Dependency	1.0	8.82777
TOP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6302
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29013
Perturb_11382_KD_NKX25_SRP152523	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.69786
Lung adenocarcinoma_LUAD_TCGA-38-4626-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LRIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83783
abnormal craniofacial morphology	MPO Gene-Phenotype Associations	1.0	null
GPSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53676
STAT3	ChEA Transcription Factor Targets	1.0	null
Perturb_12606_KO_Lin28a/Lin28b_SRP300815	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56454
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.863524
DLG4	Pathway Commons Protein-Protein Interactions	1.0	null
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34333
CAPRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14403
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
HSCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18679
Parasubiculum, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13906
KMT2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53446
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lung adenocarcinoma_LUAD_TCGA-53-7813-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
647V	CCLE Cell Line Gene CNV Profiles	1.0	1.54568
Perturb_6107_KO_Mki67_SRP295162	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.87825
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4234
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22221
Perturb_12256_KO_CD274_SRP215305	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.1109
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59486
Perturb_4716_KD_Hnrnpu_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.26446
COPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26226
Taenia tecta, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81048
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
ANKRD40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15541
Perturb_2716_KO_TET1_SRP110516	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.28832
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09389
Calcium	HMDB Metabolites of Enzymes	1.0	null
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
skin cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Tcf21	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.9832
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898242
Perturb_533_OE_EWSFLI1_SRP033559	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.59069
SECISBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98255
GSE180200,GSE180201_2_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_12572_KD_MSI1_ERP124202	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.06665
GSE137144_2_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
transporter activity	GO Molecular Function Annotations 2015	1.0	null
KPNYS	DepMap CRISPR Gene Dependency	1.0	5.97338
negative regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_11707_KD_NUDT21_SRP127253	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.23585
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19906
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03705
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7842
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25777
Gill raker	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.343
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
cingulate gyrus, frontal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.938008
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.518
POLR2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96443
Blastodisc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.828
intermediate stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28723
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
monoatomic cation transmembrane transport	GO Biological Process Annotations 2023	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00342
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.68009
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12522
TMED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55973
heterozygosity	GeneRIF Biological Term Annotations	1.0	null
GSE213588_10_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XK95-1026-SM-4GIDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Transmembrane transport of small molecules	Reactome Pathways 2014	1.0	null
MEL270	DepMap CRISPR Gene Dependency	1.0	3.31153
Cycloplegia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
Hyperopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.307
Perturb_4570_KD_Hnrnpf/Hnrnph1_SRP186998	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.55668
OE33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_12239_KO_ZMYND8_SRP130942	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.50076
Mel-Ab cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.557
Perturb_14485_OE_Tp73_SRP134969	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.01835
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03705
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.5029
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q4-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tooth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.524
Perturb_15752_KO_Ezh2_SRP096837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BTBD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47552
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884756
REST	ChEA Transcription Factor Targets	1.0	null
Septofimbrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20682
Myocardial Infarction	dbGAP Gene-Trait Associations	1.0	0.80383
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ABL1_knockdown_137_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.4866
Psychiatric Status Rating Scales	HuGE Navigator Gene-Phenotype Associations	1.0	null
Perturb_9286_KD_LMTK2_SRP276928	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.00876
Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inorganic ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
GTEX-OHPN-0008-SM-4E3HW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E4-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49685
digits	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34871
Dermatosis papulosa nigra	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.578
Outer nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.055
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Retinal pigment epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_7587_KO_ALKBH5/FTO_SRP362871	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.55999
RARB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25133
KYSE-220	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05215
calcium, potassium:sodium antiporter activity	GO Molecular Function Annotations 2023	1.0	null
GSE213588_10_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_85_KD_CSN5_SRP316687	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.88539
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17878
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	1.10404
ZNF74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31935
SMAD4-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.852247
abnormal outer ear morphology	MPO Gene-Phenotype Associations	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16305
Perturb_18442_KD_YAP1/WWTR1_SRP303519	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.66616
Lung adenocarcinoma_LUAD_TCGA-99-8025-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4519_OE_Zfp708_SRP186171	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.34466
NTAQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26002
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5491
Perturb_3622_KO_SMARCC2_SRP127343	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.68503
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.899753
MCOLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19657
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
confers	GeneRIF Biological Term Annotations	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897317
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48275
epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947132
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_14920_Mut_Atxn3_SRP155020	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.88536
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Hematopoietic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.527
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04041
iris hypoplasia	MGI Mouse Phenotype Associations 2023	1.0	null
bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.002908
epidermis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
trans-golgi network membrane	GO Cellular Component Annotations 2015	1.0	null
Hypopigmentation Disorder	DisGeNET Gene-Disease Associations	1.0	null
abnormal dermal pigmentation	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GSE226452_1_v_2_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GPR153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82721
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
abnormal iris morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-OXRP-0926-SM-48TC1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
KYAE1	DepMap CRISPR Gene Dependency	1.0	2.10041
GSE145639_7_v_2_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_4759_KO_DLG2_SRP315088	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.23161
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03011
GTEX-UPIC-1026-SM-4IHLT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09139
Melanoma cell line	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-UPJH-0626-SM-4IHJN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908196
Perturb_3958_KO_GSDMB_SRP350967	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-19.0969
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75229
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.815961
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4876-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42684
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0633
MCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67518
Perturb_11565_KD_BAX/BAK_SRP348085	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
lateral terminal nucleus of the accessory optic tract, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.72736
DNAAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54147
Perturb_1707_KD_Rad21_SRP132608	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Perturb_12316_KD_CDKN1B_SRP136720	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.6992
Perturb_4367_KO_Peg10_SRP167954	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.8911
GSE251992_1_v_0_saracatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.10011
GTEX-Q734-0726-SM-48TZP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
SAMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1316
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_15214_KD_KLF4_SRP255722	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.1249
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7103-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral (dentate) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04729
GSE213588_8_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.18668
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7391-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_4352_KD_EP300_SRP068733	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.07409
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.504
P300-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6164
inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Amelanotic melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.021
PMC10528072-NIHMS1928302-supplement-5.xlsx-NEUROD1-target_genes-AANAT_NEUROD1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_1335_KO_Esrra/Esrrg_SRP143464	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.50496
RUNX2	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
periventricular stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52511
monoatomic ion transport	GO Biological Process Annotations 2025	1.0	null
SCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03484
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7393-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_8718_KD_RPL39_SRP385284	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.64479
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
r2 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07134
ventral subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76826
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-h-Classification_of_camel_SON_basal_genes_-_transporters_SON	Rummagene Transcription Factor Associations 2026	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
Perturb_13989_KO_Polr2a_SRP181107	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
liver	GTEx Tissue Gene Expression Profiles	-1.0	-2.08937
Perturb_3842_KD_NUAK1_ERP105460	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.64964
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.91601
PBRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62681
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MMGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75102
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F5-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VEZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59672
ENTPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79478
Sarcoma_SARC_TCGA-WP-A9GB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5264_OE_Dcaf11_SRP328699	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.65398
BOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84631
PEO4	DepMap CRISPR Gene Dependency	1.0	3.43159
Perturb_4931_OE_KLF17_ERP131959	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.47537
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963322
Perturb_1382_KO_Sdc1_SRP286584	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.8645
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19725
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10769
abnormal skin pigmentation	MPO Gene-Phenotype Associations	1.0	null
Perturb_757_KO_DNMT3B_SRP389363	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.30436
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898242
Inflammation	CTD Gene-Disease Associations	1.0	1.08868
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0268
ZNF273	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04424
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.38224
GTEX-P78B-2226-SM-3P5ZZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.946581
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A97Q-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13239_KO_Flcn_SRP126727	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.26045
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958524
Perturb_13572_KD_Setdb1_SRP059699	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.16004
Fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.73
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Sox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.0367
Pontine central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64288
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0258
Nucleus y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15648
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46684
GSE137144_3_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.9169
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
17616640-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11279
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-RM2N-0726-SM-48FD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GATA1_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184902_4_v_1_adipor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11461876-42003_2024_6975_MOESM3_ESM.xlsx-Supplementary_Data_1-Supplementary_Data_1_Differentially_Expressed_Genes_HSE_THP1_Vs_THP1_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Sarcoma_SARC_TCGA-FX-A3RE-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913957
MRPL57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85427
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15075
Myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
slc45a2	GeneRIF Biological Term Annotations	1.0	null
abnormal extracutaneous pigmentation	MPO Gene-Phenotype Associations	1.0	null
Penis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.198
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13195_KO_HDAC3_ERP127280	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.63747
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08054
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Perturb_3729_KO_Arid5a_SRP288358	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.46997
GTEX-UPIC-1826-SM-4IHKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974473
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
NHEM cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.523
888	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.57559
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
key	GeneRIF Biological Term Annotations	1.0	null
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.316224
GSE239578_0_v_6_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17371
Perturb_13047_KO_YAP1/WWTR1_SRP212218	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.50179
KAP1-22055183-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.21697
GSE179974_3_v_5_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PNPLA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85894
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.20867
GSE112860_0_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NKRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93395
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977086
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11428
FAM216A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80276
layer 2 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.40712
brain	HPA Tissue Gene Expression Profiles	1.0	1.25004
mediodorsal nucleus of thalamus_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10888
Perturb_268_KO_ADIRFAS786_SRP366780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.51989
USF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62142
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61394
GTEX-WEY5-2326-SM-3GIKK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890334
disease	GWASdb SNP-Disease Associations	1.0	0.04787
GSE168797_2_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
SCYL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07263
r3 part of parvicellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30696
Perturb_5198_KO_Tsc2_SRP125196	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.05177
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34227
AAGAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42641
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
abnormal eye pigment epithelium morphology	MPO Gene-Phenotype Associations	1.0	null
tyrosinase	GeneRIF Biological Term Annotations	1.0	null
calcium:sodium antiporter activity	GO Molecular Function Annotations 2023	1.0	null
Dorsal fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Perturb_17666_KO_Smad2/Smad3_SRP137054	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.31712
characterized	GeneRIF Biological Term Annotations	1.0	null
Perturb_8057_KD_IGF2BP3_SRP094100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.945
Perturb_6619_KO_NEUROD1_SRP388830	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.84695
GSE112860_5_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954381
OXSM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65849
Perturb_1812_KO_N4bp1_SRP255180	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Perturb_4369_KD_SUZ12_SRP071040	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.15173
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.840457
neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.387027
QSOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34031
Tuber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.813
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19093
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B1-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Feather	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.877
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9361
Perturb_553_KD_KDM5A_SRP277893	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.3727
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41519
Perturb_14944_KD_Nmnat1_SRP102079	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.79469
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4720_KD_Tp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Perturb_8133_KD_EIF4B_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.65706
Perturb_5710_KO_Dgcr8_SRP043436	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
single-organism localization	GO Biological Process Annotations 2015	1.0	null
previously	GeneRIF Biological Term Annotations	1.0	null
SDF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42023
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
Stratum intermedium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.828
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.22543
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.627485
hirschsprung's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.377402
Perturb_432_KD_RPAP3_DRP004966	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.95258
Perturb_3471_Mut_Atxn1_SRP148491	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.07789
Lung adenocarcinoma_LUAD_TCGA-62-A472-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMRTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24625
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30807
Perturb_16845_KO_Kcnj10_SRP241402	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.71604
Perturb_4955_KO_Zbtb2_ERP125291	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.82199
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZC3HC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33626
Perturb_13069_KO_Cry2_SRP091906	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.55974
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50344
Perturb_2050_KO_Bmal1_SRP124290	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.47165
Perturb_10127_Mut_MYB_SRP080924	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.53274
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095809
primary auditory cortex (core)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02261
Perturb_28_OE_Smad1_SRP217699	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.83947
RPS6KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96463
abnormal ciliary body pigmentation	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02695
degeneration of macula and posterior pole	GWASdb SNP-Disease Associations	1.0	0.918934
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Hoof	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.534
low	GeneRIF Biological Term Annotations	1.0	null
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965916
Perturb_463_KO_IGF2BP1_SRP251874	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.68087
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8857
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
melanosome	GO Cellular Component Annotations 2015	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Chiasma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.727
PIWIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20264
Vitiligo	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.783
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.707
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.958
ZNF212	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6063
loeys-dietz syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.859362
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1813
GSE150557_1_v_0_dnmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
absent eye pigmentation	MPO Gene-Phenotype Associations	1.0	null
SLC38A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23545
nonsyndromic	GeneRIF Biological Term Annotations	1.0	null
GTEX-XBED-1026-SM-48TCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6632
embryoday10.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.30201
Perturb_269_KD_SNIP1_SRP322020	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.09614
Perturb_9649_KD_T208_SRP327946	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.0746
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78456
albinism, oculocutaneous, type vi	OMIM Gene-Disease Associations	1.0	null
Uveal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
myocardial infarction	GAD Gene-Disease Associations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24074
Perturb_5288_KD_Rpl10a_SRP064202	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.15129
UBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95242
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.35742
OCEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45912
pyramidal cells of rostral CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.82507
Perturb_2132_KD_HAPSTR1_SRP377309	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.31084
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.38212
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
suggesting	GeneRIF Biological Term Annotations	1.0	null
Perturb_8993_OE_LIMA1_ERP128082	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.3468
Oculocutaneous albinism type II	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.256
TE4	CCLE Cell Line Gene CNV Profiles	1.0	1.57986
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884089
Perturb_4952_KO_Zbtb2_ERP125292	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.55891
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
trans-golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.340773
THOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81179
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
abnormal ear pigmentation	MGI Mouse Phenotype Associations 2023	1.0	null
abnormality of the integument	HPO Gene-Disease Associations	1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.91225
melanosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1418
Perturb_13779_OE_IL10RB_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867972
SZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.824501
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03114
symporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_11933_KD_RNF5_SRP276909	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.55184
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
eye	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
amygdaloid complex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.07823
GSE107505_0_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPJH-0926-SM-4IHKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03444
Perturb_8200_KD_FUBP3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.44921
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
CTCF	ENCODE Transcription Factor Targets	1.0	null
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE213588_9_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
pigmentation	GeneRIF Biological Term Annotations	1.0	null
Perturb_2343_KD_KRT5_SRP342396	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.88976
Cone photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.046
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63942
SAP30BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41113
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.644207
Perturb_11910_KD_Hmga2_SRP029975	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.9102
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12385
COR-L279	COSMIC Cell Line Gene Mutation Profiles	1.0	null
INO80E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03345
ciliary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.612958
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.07626
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59147
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40123
network	GeneRIF Biological Term Annotations	1.0	null
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37735
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07017
NME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28489
Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5642
Perturb_6523_KD_YTHDF2_SRP239270	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.30978
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE239844_7_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.905447
UO31	CCLE Cell Line Gene CNV Profiles	-1.0	-2.28479
PUSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42529
Perturb_13236_KO_Flcn_SRP126727	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.119
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.228
abnormality of the fundus	GWASdb SNP-Phenotype Associations	1.0	0.217679
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
periventricular stratum of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93853
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
r5 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41921
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sickle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.093
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.951451
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.111
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1975_KO_Ogt_SRP250299	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.253
calcium ion homeostasis	GO Biological Process Annotations 2025	1.0	null
regulator	GeneRIF Biological Term Annotations	1.0	null
Trunk	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hypopigmentation	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_5245_KO_Ssrp1_SRP276644	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.85668
PSMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55756
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
Perturb_13316_KD_Foxc1_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.55779
PMC8755441-mmc3.xlsx-IRF3-signif-Symbol_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
paraterminal gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.15799
metal ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
ICAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20194
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.58045
Cytoplasmic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.045
Perturb_10216_KO_Csnk1a1/Trp53_ERP021472	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.36149
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10363_KD_Rorc_SRP185851	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.19001
Elongator holoenzyme complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.577
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.848972
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
COLO800	CCLE Cell Line Gene CNV Profiles	1.0	1.38563
pl374f	GeneRIF Biological Term Annotations	1.0	null
Perturb_4933_OE_KLF17_ERP131758	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.89828
cell part	GO Cellular Component Annotations 2015	1.0	null
Perturb_8708_KD_Irf2_SRP193480	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.0371
Perturb_1800_KO_Hif1a_SRP198677	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.76679
Perturb_9504_KO_Il33_SRP076391	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.96136
GTEX-TML8-1626-SM-32QOO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902928
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE223540_1_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.954149
GSE188884,GSE189078_2_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cheek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.077
GRIN2A	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_8303_KD_SRFBP1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.72712
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.944126
any	GeneRIF Biological Term Annotations	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-RQ-A68N-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34128
abnormal ear morphology	MPO Gene-Phenotype Associations	1.0	null
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
rab9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.705
FADU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A6-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.036
Perturb_5206_KO_Dgcr8_SRP137729	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.01866
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09207
FOS	ENCODE Transcription Factor Targets	1.0	null
Perturb_1898_KO_Rbpj_SRP033707	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.99602
GTEX-QXCU-0926-SM-48FEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10127
abnormal iris pigmentation	MPO Gene-Phenotype Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70O-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DOV13	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35344
GTEX-QCQG-1726-SM-3GIJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17775
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.967934
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.99961
GSE176008_0_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38208
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.76506
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4349-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.991181
Perturb_16445_KO_MITF_SRP298756	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.73412
SLC-mediated transmembrane transport	Reactome Pathways 2014	1.0	null
Perturb_2770_KD_HOXA11_SRP072302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.27437
LIN7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69326
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51268
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Nucleoplasmic THO complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.017
residue	GeneRIF Biological Term Annotations	1.0	null
marker	GeneRIF Biological Term Annotations	1.0	null
ancestry	GeneRIF Biological Term Annotations	1.0	null
Perturb_5253_KD_Snd1_SRP311785	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
CORL24	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36257
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.949456
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0721
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2521
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.9088
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3629
TFAP2A	ChEA Transcription Factor Targets	1.0	null
Basal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11923
Perturb_14050_OE_NFIB_SRP281947	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.40583
genetic	GeneRIF Biological Term Annotations	1.0	null
GSE211177,GSE211178_8_v_1_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
ITCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78379
Perturb_2763_KD_CBX3_SRP077334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.4437
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
P53-22387025-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_15488_KD_SIM2_SRP218853	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.69362
CXXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24804
VDAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98893
CMBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41909
Perturb_7180_KO_TrEx_SRP163035	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.0938
Retinoschisis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.62336
Perturb_9560_KO_Marchf3_SRP278315	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.82147
Stratum corneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.24
dorsolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.5485
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_7205_KD_U2AF1a/U2AF1b_ERP006200	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.75243
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.548
Perturb_11520_KD_PI4KB_SRP162839	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.59992
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839898
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13324
BB49-HNC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE226249_2_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.79382
outer CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.870334
EBF1-22473956-BONE-MARROW-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormal retina morphology	IMPC Knockout Mouse Phenotypes	1.0	null
Perturb_1751_KD_lncRNA12928_SRP174348	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.46894
optic cup	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.836575
navicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22174
calcium channel activity	GO Molecular Function Annotations 2023	1.0	null
Kidney Failure, Chronic	HuGE Navigator Gene-Phenotype Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-A46P-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11631
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RJ-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR3	ChEA Transcription Factor Targets	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15808
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
TAL1_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metal ion transport	GO Biological Process Annotations 2015	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A8F3-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45579
PMC3840000__F1	PFOCR Pathway Figure Associations 2023	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10454
Perturb_2591_OE_YBX1_SRP100638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.25252
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
negative regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38766
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07852
Aplasia Of The Bone	DisGeNET Gene-Phenotype Associations	1.0	null
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01789
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_1809_KO_Irf5_SRP186268	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.36557
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
RHOU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30401
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.137
informative	GeneRIF Biological Term Annotations	1.0	null
Perturb_2347_KD_ELP3_ERP122258	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.88531
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
ZNF80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60566
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00979
periventricular stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1144
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56002
SP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.880159
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0
Upper epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.88
retina	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-U8XE-1926-SM-3DB98	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
PMC9314667-Table_1.xlsx-Regulons-IRF4_IRF4	Rummagene Transcription Factor Associations 2026	1.0	null
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897317
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839898
GSE66931,GSE73382_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DSG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91122
KATNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44884
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
outer CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03438
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_598_OE_HOTAIR_SRP342161	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_12496_KD_TP53_SRP364608	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.52125
EEF1AKMT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40042
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EG-06A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Restless legs syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.707
ARHGEF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28593
Lung adenocarcinoma_LUAD_TCGA-91-A4BC-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14611_KO_MTAP_SRP186070	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Lung adenocarcinoma_LUAD_TCGA-86-8279-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDIPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17913
Perturb_6353_KO_Smn_SRP253847	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.47556
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.8338
AP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
T84	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.03678
Perturb_4782_KD_Trim24/Trp53_ERP019861	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.84497
Perturb_4814_KO_Neil1_SRP193096	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.47023
ZNF143_02_59	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.80735
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
abnormal skin morphology	MPO Gene-Phenotype Associations	1.0	null
PMC11979751-table_s2_markers_elad055.xlsx-Melanoma_GSEA_state_markers-AP1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_15608_KO_Dnmt1_SRP247926	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.6641
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.845991
Perturb_4340_OE_MIR9/MIR124_SRP271657	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	19.5229
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Perturb_9669_KO_NR1H4_SRP115904	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.44915
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60362
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
calcium:cation antiporter activity	GO Molecular Function Annotations 2015	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.47666
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19121
K5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03396
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.336081
Perturb_5158_KD_Zic3_SRP046299	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.89429
Perturb_10803_KO_Bmal1_SRP090360	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.32354
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.74138
plasma membrane-derived chromatophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.552251
GSE189834,GSE189836_1_v_0_brd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Orbital area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24793
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.893854
Perturb_2598_KD_PRMT6_SRP131294	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.92814
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54319
r7 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46241
layer 1 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01374
CMLT1	DepMap CRISPR Gene Dependency	1.0	2.61919
GSE246195,GSE246305_2_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Macular Degeneration	dbGAP Gene-Trait Associations	1.0	0.259839
Neural crest	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.9
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044451
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05435
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A149-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subcallosal cingulate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17808
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GSE135350_3_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
among	GeneRIF Biological Term Annotations	1.0	null
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.956469
intracellular monoatomic cation homeostasis	GO Biological Process Annotations 2023	1.0	null
ANAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11679
KLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3039
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.859457
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
prevalence	GeneRIF Biological Term Annotations	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.60083
GSE235596_0_v_1_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22464
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28524
Memory Disorders	CTD Gene-Disease Associations	1.0	1.06333
Golgi apparatus subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
all	HPO Gene-Disease Associations	1.0	null
LNZTA3WT4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_16850_KO_Hnrnph1_SRP068520	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.18746
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78506
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-574-ZSCAN1_ZSCAN1	Rummagene Transcription Factor Associations 2026	1.0	null
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
ehlers-danlos syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.530381
molecular_function	GO Molecular Function Annotations 2015	1.0	null
RBIS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58344
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.708808
Perturb_4900_KD_NANOG_SRP158631	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.7537
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02044
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6662
aortic aneurysm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.242595
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_MYC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GSE202587_1_v_0_xrn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03705
PRICKLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62038
GTEX-X8HC-2726-SM-46MUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
SNU46	DepMap CRISPR Gene Dependency	1.0	2.01814
Retinal pigment epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.81
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18119
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00827
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56365
inorganic cation transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Carcinoma, Basal Cell	HuGE Navigator Gene-Phenotype Associations	1.0	null
Malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.835
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.990197
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
SJSA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
reveals	GeneRIF Biological Term Annotations	1.0	null
Perturb_7474_KD_Chtopl_SRP144331	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.2273
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5823
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.358228
Perturb_2458_KD_ESR1_SRP268806	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.7696
posterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67931
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851093
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94776
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.74504
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.91107
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99708
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6653
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65D-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9222488__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Perturb_6408_KD_LINC00152_SRP134387	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.3979
r2 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07477
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20892
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20999
europeans	GeneRIF Biological Term Annotations	1.0	null
Perturb_8038_KO_FOXA2_SRP350523	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.75092
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
TBC1D15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52284
GSE110440_1_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
RARRES1_KD_GDS4818_314_human_SUM149	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
C5orf22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88778
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0725
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
TSACC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2851
Perturb_14153_KO|KD_KBTBD4|RCOR1_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.7852
GSE180200,GSE180201_3_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58059
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.22606
Perturb_17318_KO_Ddx5_SRP284247	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.42086
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_4485_OE_Mir29a/Mir29b1_SRP220351	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.03128
intracellular monoatomic cation homeostasis	GO Biological Process Annotations 2025	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A71Z-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41373
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-U8XE-1726-SM-4E3IF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_8815_KD_INTS12_SRP073445	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.84874
GSE169205_0_v_8_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72555
FBXO28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09304
Perturb_14919_KO_Polr2a_SRP181107	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.0486
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.860349
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Perturb_3606_KO_ARID2_SRP127343	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.32265
GSE137818_5_v_0_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_12568_KD_Sufu_SRP194252	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Perihypoglossal nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64856
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.862261
r6 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35847
APCS	Pathway Commons Protein-Protein Interactions	1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.09045
Calcaneal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.44763
PU1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.893916
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.31747
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.51324
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Skin reflectance (Melanin index)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.93979
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00988
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09757
Ductus Arteriosus, Patent	HuGE Navigator Gene-Phenotype Associations	1.0	null
MSLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57998
neural plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.170426
SCAMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19987
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
KRTCAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39579
skin carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.222822
COLO679	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14514
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Uterine Carcinosarcoma_UCS_TCGA-N5-A59F-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SN-12C cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.677
r1 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04691
macular degeneration	GWASdb SNP-Phenotype Associations	1.0	0.808534
intracellular calcium ion homeostasis	GO Biological Process Annotations 2023	1.0	null
COLO800	DepMap CRISPR Gene Dependency	1.0	2.17996
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22627
Perturb_8470_KD_MITF_SRP048577	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.4079
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A410-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEMA4G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67853
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13122
GSE139016_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.62781
NFAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82024
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
Pathologic nystagmus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.961
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.105863
FOS_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11975_KO_Star_SRP302975	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.30789
ACVR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26718
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3907
NB4	DepMap CRISPR Gene Dependency	1.0	3.57394
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.637
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5185-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04236
NATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10343
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
16166618-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.74982
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GR-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52165
HARA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.385
Perturb_2901_KD_HDAC1_SRP327853	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.9062
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15961
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.896895
RAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32036
Perturb_2385_KO_ASXL2_SRP333775	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.88001
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01714
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4878-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_17550_KD_HMG20A_SRP354496	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.11088
superficial stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.72736
Griscelli syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.028
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Gene_Name_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Aland Island eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.86
GSE169205_0_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
behavioral abnormality	HPO Gene-Disease Associations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YF-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hair follicle outer root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.764
calcium ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64856
SEZ6L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33399
Perturb_13230_OE_Rnaseh1_SRP056871	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.04873
nucleus incertus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35092
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17993
Perturb_15560_KO_SLFN11_SRP327912	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.17459
PHPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79858
GTEX-UTHO-1826-SM-3GAFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.950681
increased grip strength	IMPC Knockout Mouse Phenotypes	1.0	null
STAT4-19710469-TH1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01086
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal hair shaft morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04109
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.870819
CYLD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0096
GTEX-PWN1-2526-SM-48TDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-SN8G-0526-SM-32PLE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19185
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15123
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial (fastigial) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33141
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Achromatopsia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.438
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.918681
SHQ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62367
CYSRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51781
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.65
abnormality of the hair	HPO Gene-Disease Associations	1.0	null
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68816
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.983101
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Piperonyl Butoxide	CTD Gene-Chemical Interactions	1.0	null
retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.077919
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE155031_5_v_1_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12945
Perturb_4876_KD_BANCR_SRP135857	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.4509
Perturb_3007_KD_Satb1_SRP068358	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.11322
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3354
Diethylnitrosamine	CTD Gene-Chemical Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A724-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21707
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_4826_KD_Nfya_SRP149362	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.81135
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	2.12032
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041792
establishment of localization	GO Biological Process Annotations 2015	1.0	null
Perturb_12038_KO_Trps1_SRP201986	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.53186
RABEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46545
PRRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87394
Perturb_13071_KO_Cry2_SRP091906	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.97331
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
postcentral gyrus, right, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26258
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.938687
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Chitosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.206
Tegmental reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03011
GTEX-S7SF-2126-SM-3K2B2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906091
Lung squamous cell carcinoma_LUSC_TCGA-43-7656-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
albinism, oculocutaneous	GAD Gene-Disease Associations	1.0	null
skin	GeneRIF Biological Term Annotations	1.0	null
GSE110268_1_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73688
GTEX-S33H-0008-SM-4AD6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Syndrome	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Hermansky-Pudlak syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.124
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE62974_1_v_0_epas1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_13231_OE_Rnaseh1_SRP056871	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MT-ND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7337
precentral gyrus, right, bank of the precentral sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29797
MFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29553
MED22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63369
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11275
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67369
abnormal eye physiology	HPO Gene-Disease Associations	1.0	null
OVTOKO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3381
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13981_KD_Elavl2/Elavl3/Elavl4_ERP133202	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19291
abnormal melanocyte morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-OXRN-1726-SM-3NM9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_3096_KO_Kmo_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.40109
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4714-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4910_OE_NR5A1_SRP111466	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.891644
Perturb_8222_KD_AKAP8L_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.0252
Perturb_17629_KO_TAOK1_SRP153109	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.99232
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3908
Oculocutaneous albinism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.465
Perturb_3070_KO_Asb15_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.7951
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Anterior segment dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54682
EBF1-22473956-LYMPHODE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43797
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34588
Perturb_13277_KO_Bach1_SRP238575	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
globe disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.448817
Hair shaft	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.445429
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
abnormal head morphology	MPO Gene-Phenotype Associations	1.0	null
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67305
Perturb_6448_OE_KPC1_SRP198764	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.2531
PIK3R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05113
Perturb_4709_KO_Hesx1_ERP023509	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.22611
NCIH211	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3322
abnormal uvea morphology	MPO Gene-Phenotype Associations	1.0	null
Perturb_12132_KO_Irf8_SRP265130	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Lung squamous cell carcinoma_LUSC_TCGA-58-8386-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
PMC6887651-Table_1.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.868368
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
increased circulating sodium level	IMPC Knockout Mouse Phenotypes	1.0	null
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GATA1	ENCODE Transcription Factor Targets	1.0	null
Perturb_3562_KD_NOTCH3_SRP174604	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.46526
FOXI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34088
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18542
STRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69386
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1297
SKMEL19	DepMap CRISPR Gene Dependency	1.0	2.05481
Orbital area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29983
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30223
Perturb_5551_KO_FBXO11_SRP149805	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.2676
SUZ12-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.59461
hearing/vestibular/ear phenotype	MPO Gene-Phenotype Associations	1.0	null
icSARS CoV_0Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.93559
normal	GeneRIF Biological Term Annotations	1.0	null
Sweat gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.628
Perturb_14051_OE_NFIB_SRP281947	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.39826
pigment granule	GO Cellular Component Annotations 2015	1.0	null
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34286
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.923848
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.872655
Perturb_13264_KO_chr7_SRP162484	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.0859
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
PMC8872993-41380_2021_1274_MOESM4_ESM.xlsx-Table_S6-Supplementary_Table_S6_Differentially-Expressed_Genes_after_T-3_KD_in_hiPSC-derived_Astrocytes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.346
MECOM	ChEA Transcription Factor Targets	1.0	null
Eye color (brightness)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	4.90969
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11983
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-S4Q7-0626-SM-4AD5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
POLR3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84324
Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8139_KD_IGF2BP3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.27818
Perturb_5316_KD_Xpr1_ERP133250	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.715
camptodactyly-arthropathy-coxa vara-pericarditis syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.956128
Perturb_4758_KO_DLG2_SRP315088	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.978
SOX2	ChEA Transcription Factor Targets	1.0	null
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.77865
KDM3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66316
periventricular stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07116
retinal disease	GWASdb SNP-Disease Associations	1.0	0.227331
Prostate adenocarcinoma_PRAD_TCGA-XQ-A8TA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
GTEX-WEY5-1326-SM-3GILS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_4713_KO_Hnrnpu_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.9405
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89091
Chronic Kidney Disease	DisGeNET Gene-Disease Associations	1.0	null
TMEM87B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12018
GTEX-S341-1226-SM-4AD5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
MASP2	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6938-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tietz syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
collagen disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.110891
Aniridia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48441
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_14052_OE_NFIB_SRP281947	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.98897
superficial stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96853
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24883
Perturb_11100_KO_Bmal1_SRP063940	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.32354
BGC823	CCLE Cell Line Gene CNV Profiles	1.0	1.33994
frontal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.81085
GSE140092_0_v_1_socs3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular calcium ion homeostasis	GO Biological Process Annotations 2025	1.0	null
Oculocutaneous Albinism	DisGeNET Gene-Disease Associations	1.0	null
calcium ion import	GO Biological Process Annotations 2025	1.0	null
Perturb_9389_KO_IRF3_SRP148971	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.4412
Piebaldism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.917
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925179
GSE134191_3_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7509_OE_ILF3_SRP195616	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.86793
MITF	ChEA Transcription Factor Targets	1.0	null
MOLT-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_3610_KO_BCL7B_SRP127343	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.33532
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24657
Lung squamous cell carcinoma_LUSC_TCGA-56-8201-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Neural arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
HCC1806	CCLE Cell Line Gene CNV Profiles	1.0	2.6305
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27758
Schizophrenia	HuGE Navigator Gene-Phenotype Associations	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
integumentary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.42589
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.48437
even	GeneRIF Biological Term Annotations	1.0	null
BRSK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90723
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	2.89776
generalized abnormality of skin	GWASdb SNP-Phenotype Associations	1.0	0.335183
Perturb_1387_KO_IPO13_SRP128496	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.16478
potassium ion antiporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GSE139948_3_v_6_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2556
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5L3-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_10_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Albinism, Oculocutaneous	HuGE Navigator Gene-Phenotype Associations	1.0	null
abnormal retinal pigmentation	MPO Gene-Phenotype Associations	1.0	null
DCPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50074
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.281
GSE180200,GSE180201_15_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
External male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.179
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93287
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_3066_KO_Adamts15_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.62034
Pulmonary hypertension	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.552
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03671
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839898
Taenia tecta, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43857
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0769
SREK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66371
Ltk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.549
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7927
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6101
Perturb_4680_KO_Psip1_SRP153901	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Rectal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.992
Medial geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37336
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899504
substantial	GeneRIF Biological Term Annotations	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6159
Perturb_17712_KD_PPARG_SRP383556	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.55964
GSE223540_0_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112860_0_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Waardenburg syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.941
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22765
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39226
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.72235
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44073
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57101
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-2576-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.3792
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.49677
DLD-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03757
r1 part of vestibular nucleus Y	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.93711
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47842
Perturb_14019_OE_Nras_SRP332459	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.6807
PMC2700213__F1	PFOCR Pathway Figure Associations 2024	1.0	null
occur	GeneRIF Biological Term Annotations	1.0	null
Skin Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44315
Corneocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.996
cerebellar nuclei of CbV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33119
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4355-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9014
Age related macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.00245
Acute Myeloid Leukemia_LAML_TCGA-AB-2975-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863101
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.861337
TAL1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.976752
Perturb_13761_KO_Hotair_SRP026100	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.72547
abnormality of the retina	GWASdb SNP-Phenotype Associations	1.0	0.235762
GSE147662_3_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal retinal pigment epithelium morphology	MPO Gene-Phenotype Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.971201
Perturb_659_KD_lncRNA_166788_SRP093784	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.53025
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.22335
Perturb_1895_KO_Trem2_SRP173901	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.36946
GSE215086_0_v_2_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
skin disease	GWASdb SNP-Disease Associations	1.0	1.95812
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
Nucleus of the lateral lemniscus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02909
ventrolateral prefrontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.6418
GSE143847_2_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72557
Perturb_15850_KO_Etv5_SRP165224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95611
Perturb_6685_KD_SMARCA2_SRP378606	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_5280_KO_Ddx6_SRP137728	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.31223
epidermal cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_14924_KO_Atxn3_SRP155020	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.61892
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5052
unreported	GeneRIF Biological Term Annotations	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02721
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25059
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5693
Melanosome lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.184
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
IZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.884363
SCLC-21H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.955036
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08876
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986315
Pigment granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.2
Stellate reticulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
Perturb_6502_KO_SOCS3_SRP168556	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.0714
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.35573
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4VX-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13867_KD_KDM6B_SRP258989	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1044
ZNF670	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47766
regulation of melanin biosynthetic process	GO Biological Process Annotations 2015	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11934
melanoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Abnormal Iris Pigmentation	DisGeNET Gene-Phenotype Associations	1.0	null
posteroventral (inferior) parietal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39032
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
CCDC124	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0669
TCF4	ChEA Transcription Factor Targets	1.0	null
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852746
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.936178
Perturb_8368_KD_IGF2BP3_SRP094100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.5038
Oculocutaneous albinism type IV	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.473
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01277
Perturb_13330_KD_Nfat5_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.65448
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.36504
AIFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54051
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.869434
Inner plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.879
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QK-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.990995
59M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85037
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6665
TRAPPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20013
Perturb_648_KD_lncRNA_041249_SRP093784	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.47001
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9905
SMG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65944
calcium ion transport	GO Biological Process Annotations 2015	1.0	null
Perturb_13256_KD_Phf5a_SRP083772	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.94083
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.634358
Perturb_1838_KO_Phlpp1_SRP151389	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.42856
GSE171724_4_v_6_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_8766_KD_H19_SRP073245	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.884
SNU668	CCLE Cell Line Gene CNV Profiles	1.0	1.50065
H3-3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49763
VWCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68027
skin pigmentation	GAD Gene-Disease Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-5899-01A-11R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YSCCC	DepMap CRISPR Gene Dependency	1.0	2.67044
Perturb_7306_KD_IER3_SRP348787	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.84209
ARHGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22357
chromosomes	GeneRIF Biological Term Annotations	1.0	null
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
PCSK1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92717
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01801
posterior (caudal) superior temporal cortex (area 22c)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01972
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.166
TSPAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47888
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33679
thorax	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
layer 1 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.43159
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09528
Perturb_12128_KO_Dnmt3a_SRP033096	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Body mass index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02518
GTEX-WYVS-1626-SM-3NM9R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26982
Perturb_5150_KO_Thap11_ERP126456	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Perturb_10165_KD_DOT1L_SRP292382	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.7146
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27735
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.863177
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
Eye-retinal pigment epithelial cell	Tabula Sapiens Gene-Cell Associations	1.0	1.91545
GRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12478
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
RBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34572
melanosomal	GeneRIF Biological Term Annotations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23122
BNC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4093
mode of inheritance	HPO Gene-Disease Associations	1.0	null
Retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.882
Skin cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.035
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.50838
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985358
Melanophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.718
Ciliary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.072
ZNF750	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91298
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22221
BTN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28454
RUVBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3101
Stria vascularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
skin_5f	HPA Tissue Sample Gene Expression Profiles	1.0	1.46262
Perturb_4326_KO_Zcchc8_SRP187429	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.7228
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31191
NDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47326
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SS-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14810_KO_Ldah_SRP282425	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.5607
GSE137144_4_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.0533
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09903
PRDM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91608
melanocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.6955
abnormal iris transillumination	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_2958_KD_Fbxl2_SRP162815	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.5817
HUH1	CCLE Cell Line Gene CNV Profiles	1.0	1.37179
GTEX-QLQW-1226-SM-2S1Q9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
PPP2R5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9684
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0255
WM-9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55197
Eye-melanocyte	Tabula Sapiens Gene-Cell Associations	1.0	5.3715
Perturb_8929_KD_CHD4/ARID1A_SRP350011	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.28471
Mesothelioma_MESO_TCGA-LK-A4NY-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mammary gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.14976
OSC20	DepMap CRISPR Gene Dependency	1.0	2.11043
slc24a5	GeneRIF Biological Term Annotations	1.0	null
Perturb_11232_KO_Il4/Il10_SRP100781	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.2451
GSE84922,GSE84924_4_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CENPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82082
Photophobia	DisGeNET Gene-Phenotype Associations	1.0	null
GSE168676_0_v_1_dach1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRAPPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52696
RMUGS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55832
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54852
X-linked deafness 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913957
Perturb_13377_KO_Sox10_SRP267687	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.21304
abnormal skin coloration	MPO Gene-Phenotype Associations	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.69605
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	1.0	3.96859
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.392388
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02772
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.996261
Perturb_2393_KD_HIF1A/HIF2A_SRP308699	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.9263
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35211
TFAP2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54742
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.69856
Thorax	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_15997_KD_LINC00704_SRP221619	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.14209
TM31	CCLE Cell Line Gene CNV Profiles	1.0	1.50452
Perturb_4259_KD|OE_HOXB13|MEIS1_SRP201342	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.03852
Transport of inorganic cations/anions and amino acids/oligopeptides	Reactome Pathways 2024	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.48761
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Melanoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.079
NDRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.378
NOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5004
showed	GeneRIF Biological Term Annotations	1.0	null
abnormal eye pigmentation	MPO Gene-Phenotype Associations	1.0	null
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.00172
basal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.321181
OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
response to stimulus	GO Biological Process Annotations 2015	1.0	null
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.38212
Perturb_1681_KO_Nox4_SRP356837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.9818
RPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16936
sclc21h	HPA Cell Line Gene Expression Profiles	1.0	1.04677
GSE185944_2_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.844751
TEDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4344
Perturb_5251_KO_Klf2_SRP311785	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.656
GSE223008_4_v_12_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Interposed nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15888
GEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39979
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39926
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.958296
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44323
TDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66024
GBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53496
skin cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.42589
ELK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81101
Perturb_3109_KO_Plat_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.58798
RAVER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03953
populations	GeneRIF Biological Term Annotations	1.0	null
Perturb_7224_KO_CDK8/CDK19_SRP271652	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.37563
Dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49909
Skin carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.814
posterior part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04441
PATU8988S	DepMap CRISPR Gene Dependency	1.0	2.02201
influence	GeneRIF Biological Term Annotations	1.0	null
Perturb_12723_KD_ARID4B_SRP152296	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.6103
Perturb_5868_KD_Cpsf6_SRP336206	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.5328
Transport of small molecules	Reactome Pathways 2024	1.0	null
rostromedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04405
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43842
Vestibular nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12476
GNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34843
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975434
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.96411
Carcinoma, Squamous Cell	HuGE Navigator Gene-Phenotype Associations	1.0	null
isthmic vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2271
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1222
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.1785
r1 part of dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.171
LMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06828
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22799
GSE102598_1_v_2_nmda_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.21586
SCC15	CCLE Cell Line Gene CNV Profiles	1.0	1.85713
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.954306
abnormality of the integument	GWASdb SNP-Phenotype Associations	1.0	0.253294
LIN7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22085
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.46102
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0098
Perturb_403_KO_FOXM1_SRP272209	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.53468
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03705
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51763
Acute Myeloid Leukemia_LAML_TCGA-AB-2955-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryoday9.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.65733
Perturb_8217_KD_U2AF2_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.30129
Perturb_7376_KD_RBM39_ERP105778	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.50889
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
TAL1	ENCODE Transcription Factor Targets	1.0	null
A4 noradrenergic cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.52668
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81159
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12484
Perturb_6616_KO_NEUROD1_SRP388830	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.88597
KYSE220	DepMap CRISPR Gene Dependency	1.0	3.21985
Chromosome 15q11.2 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
Perturb_5395_KD_LIM1_SRP402415	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.8476
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH1573	DepMap CRISPR Gene Dependency	1.0	2.27465
Lung adenocarcinoma_LUAD_TCGA-55-8097-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Lung squamous cell carcinoma_LUSC_TCGA-37-4132-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4769-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-S4P3-1126-SM-4AD52	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05388
TAL1_megakaryocyte_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GRIN1	Pathway Commons Protein-Protein Interactions	1.0	null
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.878
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.12682
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.383509
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.918623
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TMEM101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06427
MSH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19412
Perturb_18151_KO_Cdk1_SRP287303	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.30418
LYNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36287
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928838
Ink sac	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.717
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
oculocutaneous albinism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.96427
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02524
Lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.026
JHOS2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53531
Perturb_15213_KD_BRD4_SRP255722	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.3941
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
antiporter activity	GO Molecular Function Annotations 2015	1.0	null
Croup	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
melanocyte differentiation	GO Biological Process Annotations 2023	1.0	null
Epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.468
Perturb_7267_OE_OspC3_SRP368098	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.9333
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06772
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.35573
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985358
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_9717_KD_Basp1_SRP126738	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.41806
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5491
Perturb_8753_KD_ANLN_SRP083014	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
22RV1	DepMap CRISPR Gene Dependency	1.0	4.25803
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.54283
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
SNU1544	DepMap CRISPR Gene Dependency	1.0	3.86621
Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARPE-19 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
NCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54547
CASR	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861977
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9052
abnormality of skin adnexa	HPO Gene-Disease Associations	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77025
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04722
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.3734
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52783
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A9FM-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15808
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4847-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vascular disease	GWASdb SNP-Disease Associations	1.0	0.147049
FCN1	Pathway Commons Protein-Protein Interactions	1.0	null
MM160113	DepMap CRISPR Gene Dependency	1.0	4.87635
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5108
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
ventrolateral part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12056
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.52132
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47964
CEBPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71397
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04085
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
ERA-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12026
Perturb_2590_OE_NFIB_SRP100638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.53337
Perturb_17340_KO_Plag1_SRP095348	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.75719
ISOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26643
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.552
Skin Pigmentation	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_9236_KO_Kmt2d_SRP152944	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.76268
Perturb_12072_OE|KD_Tfap2a|Tgfb1_SRP067296	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.10109
Perturb_8410_KO_Srsf1_SRP252896	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.40175
JVM-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3QU-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7179_KO_TrEx_SRP163035	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.02325
B800-820 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.605
photophobia	HPO Gene-Disease Associations	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04062
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
anterior (rostral) cingulate (medial prefrontal) cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.48981
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13558
intracellular part	GO Cellular Component Annotations 2015	1.0	null
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16869
Perturb_14842_KO_Mir290_SRP101368	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.50627
GTEX-XQ3S-1526-SM-4BOOC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4508
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983779
COX4I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99012
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3907
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A59V-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCSTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08746
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8532
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_18451_KD_H2AFJ_ERP124778	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.37357
Orbital area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20108
CCDC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28801
PMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02647
subjects	GeneRIF Biological Term Annotations	1.0	null
POU1F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74068
GSE137144_2_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_15751_KO_Zfp36l1_SRP285762	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.26614
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SU-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
frontal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.93564
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12317
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
retinal pigment epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.311507
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin/Hair/Eye Pigmentation	DisGeNET Gene-Phenotype Associations	1.0	null
eye disease	GWASdb SNP-Disease Associations	1.0	0.136631
Perturb_12885_KD_Setd2_SRP132773	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.9845
golgi apparatus part	GO Cellular Component Annotations 2015	1.0	null
kidney	HPA Tissue Gene Expression Profiles	1.0	0.859513
BRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33544
Albinoidism, Oculocutaneous, Autosomal Dominant	DisGeNET Gene-Disease Associations	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040495
Perturb_11475_KO_MUC1C_SRP402838	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.8697
Perturb_5105_KD_Rnf219_SRP251834	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.59512
OXA1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32198
SOX10	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24261
correlates	GeneRIF Biological Term Annotations	1.0	null
SLC4A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03133
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58554
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74334
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.62817
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71256
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.482817
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4017
Perturb_13784_OE_IL10RB_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.57975
dorsal subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14803
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
496100459_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1234
Parasubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26261
Lateral septal nucleus, caudal (caudodorsal) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21266
Autosomal genetic disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
orbital frontal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.61058
WFDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46077
Perturb_9450_OE_SOX9_SRP297132	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.98126
Perturb_13271_KO_Msl2_SRP192624	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.71378
regulation of secondary metabolite biosynthetic process	GO Biological Process Annotations 2015	1.0	null
abnormal eye morphology	MPO Gene-Phenotype Associations	1.0	null
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8165
Neural ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.791
Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45715
UTP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96201
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94289
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
hsa-miR-4722-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
KDM5A	ENCODE Transcription Factor Targets	1.0	null
Perturb_7623_KD_UPF1LL_SRP295982	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.41306
worldwide	GeneRIF Biological Term Annotations	1.0	null
nes	HPA Cell Line Gene Expression Profiles	1.0	0.994448
FAM53C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1434
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.85993
ES4	DepMap CRISPR Gene Dependency	1.0	2.55435
phenotype	GeneRIF Biological Term Annotations	1.0	null
Perturb_9406_KD_GATA6AS_SRP279802	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.17415
Perturb_4853_KD_NKX25_SRP059197	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.07854
Perturb_11187_KO_Trp53/Gdown1_SRP244620	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.92633
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_4436_KO_Cbs1_SRP331019	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.53388
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35499
NuA3b histone acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.854
GPATCH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07362
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23804
artery disease	GWASdb SNP-Disease Associations	1.0	0.195209
Perturb_5101_KD_Dcaf11_SRP201454	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.4332
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.759855
Perturb_5700_KO_Airn_SRP157112	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.07812
Perturb_8928_KD_CHD4_SRP350011	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.61473
Perturb_9822_KD_RUNX1_SRP103740	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.1606
NuA3 histone acetyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.591
Perturb_5317_KD_Xpr1_ERP133250	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.71778
Perturb_637_KO_SOX4_ERP117895	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.09927
Perturb_12569_KD_Sufu_SRP194252	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31788
abnormal retina pigmentation	MGI Mouse Phenotype Associations 2023	1.0	null
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.746
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8873
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839898
Perturb_7211_Mut_MED26_SRP164752	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.1359
Perturb_8471_Mut_IDH1_SRP099826	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
insular cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25596
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.45039
primary visual cortex (striate cortex, area V1/17)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13829
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826812
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AE-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Melanosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.218
Lung adenocarcinoma_LUAD_TCGA-97-7553-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal iris transillumination	IMPC Knockout Mouse Phenotypes	1.0	null
Plasma membrane-derived chromatophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.253
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
liminal alar domain of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12289
Entorhinal area, medial part, dorsal zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31131
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUJ4-2526-SM-4BOO4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.74409
496100482_PCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09055
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03593
seven	GeneRIF Biological Term Annotations	1.0	null
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.972614
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00251
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AZ-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
than	GeneRIF Biological Term Annotations	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.1785
Lung squamous cell carcinoma_LUSC_TCGA-22-4593-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872986
Perturb_4987_KO_Mettl3_SRP212677	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.41544
PDRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92321
melanocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
eurasian	GeneRIF Biological Term Annotations	1.0	null
GSE107505_3_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_13592_OE_Mir322/Mir503_SRP348669	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.83216
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00675
CAMK2D	Pathway Commons Protein-Protein Interactions	1.0	null
Adenoma	CTD Gene-Disease Associations	1.0	1.01249
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1YY-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20132
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_12704_KO_LIPA_SRP310406	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.24067
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20429
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
UBIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95626
DR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66949
GTEX-P4PP-0426-SM-3NM9H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872519
YDJC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53138
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r2 part of median raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69002
Perturb_11530_KD_THOR_SRP121007	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.8827
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18875
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.63477
Oculocutaneous albinism type IB	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.577
GSS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94572
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_4606_KD_H2A.Z_SRP345495	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
regulation of cellular biosynthetic process	GO Biological Process Annotations 2015	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850295
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-DX-A3UB-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.93775
HSPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35102
specific	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.142
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61485
Rectum adenocarcinoma_READ_TCGA-BM-6198-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5344_KO_Ilf2_SRP100469	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.95208
ER-23166858-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_2766_KD_CNBP_SRP072302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.7598
ELOA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96876
Perturb_8237_KD_QKI_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.23535
Infertility, Male	CTD Gene-Disease Associations	1.0	1.03678
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62571
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
Perturb_5654_KD_FLI1_SRP117628	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.39701
Retinal rod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.438
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01905
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GON4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76766
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.58098
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.732056
OSGEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43253
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.49355
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34378
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z6-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NANOG-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68156
Perturb_342_KD_GDF6_SRP076553	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_13939_KO_USP29_SRP329795	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.2224
Astigmatism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TMEM238	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85763
Merocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.346
SMIM10L2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75357
Perturb_7453_KD_ERI2_SRP110692	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.25222
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.71798
hippocampus (hippocampal formation)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.903613
Sodium/potassium/calcium exchanger	InterPro Predicted Protein Domain Annotations	1.0	null
decreased prepulse inhibition	IMPC Knockout Mouse Phenotypes	1.0	null
observed	GeneRIF Biological Term Annotations	1.0	null
RFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47269
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Aa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
Perturb_2723_KD_HOTAIR_SRP172688	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.88028
PMC8891017-41586_2022_4394_MOESM4_ESM.xlsx-ST6_-_MAF_enrichment-Unnamed_4_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.648
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37742
cytoplasmic membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
TC138	DepMap CRISPR Gene Dependency	1.0	3.48746
Persistent hyperplastic primary vitreous	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16998
vision/eye phenotype	MPO Gene-Phenotype Associations	1.0	null
Perturb_4904_KO_NSUN6_SRP233222	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GTEX-RN64-0726-SM-48FCV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946941
VARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70785
POU2F2	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_466_KD_ADAR1_SRP253895	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.9586
NMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Organelle subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
SMAD1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GRIN2B	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_3_AP1_Up_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
ATP1B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66956
ZIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73269
abnormal skin adnexa morphology	MPO Gene-Phenotype Associations	1.0	null
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.64
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7976
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827116
Perturb_50_KO_Kat6a_SRP215863	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.06968
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_10254_KO_WT1_ERP126063	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.65863
dorsolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10174
abnormality of the globe	GWASdb SNP-Phenotype Associations	1.0	0.134192
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4845-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endolysosome lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.827
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975039
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Perturb_16704_KO_Dock11_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.62308
Prostate adenocarcinoma_PRAD_TCGA-X4-A8KQ-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01259
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DL-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11333
GTEX-SIU8-0826-SM-2XCDQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE100886,GSE100893_1_v_3_parp14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal posterior eye segment morphology	MPO Gene-Phenotype Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
share	GeneRIF Biological Term Annotations	1.0	null
UMUC1	CCLE Cell Line Gene CNV Profiles	1.0	2.92033
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4901
shsy5y	HPA Cell Line Gene Expression Profiles	1.0	0.979215
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_58_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2794
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51959
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.977305
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.392629
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976333
NMI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00569
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07971
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.48728
TMEM165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52885
regional	GeneRIF Biological Term Annotations	1.0	null
Excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TMEM237	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17734
Hypertension	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.552
MRPS26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98974
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11132
Leprosy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.353282
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.926145
Neural retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.961
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877403
GSE130956_0_v_1_icaritin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.933474
Infant, Premature, Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE137144_3_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Hermansky-Pudlak syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.549
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64392
Perturb_3481_KO_Ccn1_SRP304010	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.8964
Suprageniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62028
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1247
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.303
SLC25A35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82524
m4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PMC11178519-CTM2-14-e1723-s002.xlsx-STab_19d_HuH28_PBX1-res_HuH28_PBX1_wt_log2FC1_pdaj0_PBX1	Rummagene Transcription Factor Associations 2026	1.0	null
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18628
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10949_KO_18O10Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.38297
active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MTHFD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18376
Keratin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.703
Perturb_14734_KD_ADAR1_SRP250165	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.87746
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.840216
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.843601
Lung squamous cell carcinoma_LUSC_TCGA-21-1076-01A-01R-0692-07,TCGA-21-1076-01A-02R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17327_KO_Lrh1_SRP328549	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.56557
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Orbital area, ventrolateral part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30702
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860818
Perturb_2236_KO_Malat1_SRP193997	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.74394
Perturb_11417_OE_proL1_SRP277436	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.34002
ACO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058001
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.3863
OB inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34041
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE179974_3_v_2_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.387
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.96619
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.43918
Perturb_1678_KO_Nox4_SRP356837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.965
FIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81548
Hyperplasia	CTD Gene-Disease Associations	1.0	1.30329
Calcitonin family receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.834
r8 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1303
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.633319
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34875
Perturb_12127_KO_Dnmt3a_SRP033096	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PMC11612249-jvms-86-1265-s001.pdf-97-BHLHE41_BHLHE41	Rummagene Transcription Factor Associations 2026	1.0	null
CNTROB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44938
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-P53_DN_V1_DN-Gene_name_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920293
GSE156115_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
Perturb_1684_KO_Nox4_SRP356837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.3341
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34086
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68729
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41699
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850295
Brain Lower Grade Glioma_LGG_TCGA-CS-6186-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06773
Rod photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.243
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.875013
GSE161184_0_v_1_tlr7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MECOM-23826213-KASUMI-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Acidocalcisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.726
Lung squamous cell carcinoma_LUSC_TCGA-77-A5GA-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4C16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.93741
MLLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47336
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4552
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.580922
Epithelium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.85702
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5707
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Transport of inorganic cations/anions and amino acids/oligopeptides	Reactome Pathways 2014	1.0	null
Perturb_15123_KD_MLL1/MLL2_SRP226048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.21756
r3 part of reticulotegmental nucleus, shell portion	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45796
Breast	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CAMK2B	Pathway Commons Protein-Protein Interactions	1.0	null
abnormal hair shaft melanin granule morphology	MGI Mouse Phenotype Associations 2023	1.0	null
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64511
GSE112714_2_v_3_ctnnb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1277_KO_Ptpn2_SRP108032	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.01359
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147662_2_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_8914_KO_KDM1A_SRP348808	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.4685
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LS 174T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34597
MARCHF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.91765
Perturb_2148_OE_RKIP_SRP189735	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.3308
PHC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1113
Retina	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MYEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10861
Perturb_13563_KD_Brd4_SRP235584	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.34734
monoatomic cation channel activity	GO Molecular Function Annotations 2023	1.0	null
nonsynonymous	GeneRIF Biological Term Annotations	1.0	null
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Perturb_14946_KD_Nmnat1_SRP102079	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.06768
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
layer 2 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28862
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3472-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_17_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
Perturb_627_KD_USO1_SRP278225	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.865
SLC30A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04316
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GSE137818_3_v_7_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
myocardial infarction	GWASdb SNP-Disease Associations	1.0	1.46002
Perturb_7508_OE_ILF2_SRP195616	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.45089
Sclerotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.79195
GTEX-OIZG-1026-SM-3LK5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
PSS008	DepMap CRISPR Gene Dependency	1.0	2.46611
MRPL37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47943
Sickle cell anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4340-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09572
Perturb_14152_KO_KBTBD4_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_14187_KD_RUNX1_SRP159178	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.406
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29113
Tail fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.708
eukaryotic translation initiation factor 2b complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.382739
AKAP9	Pathway Commons Protein-Protein Interactions	1.0	null
GSE205070_2_v_7_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
Melanocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.75
Perturb_10215_KO_Csnk1a1_ERP021472	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.01327
Lung adenocarcinoma_LUAD_TCGA-78-7537-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trans-Golgi network	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76516
decreased fasting circulating glucose level	MGI Mouse Phenotype Associations 2023	1.0	null
COLO 849	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.68774
Perturb_6409_OE_ESR2_SRP165889	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.76849
ZNF32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63099
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.552
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68298
Autoimmune disease of skin and connective tissue	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.517
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.30544
MNT-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6198
GTEX-OHPK-2526-SM-3MJH9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_17247_KD_Brd2_SRP201499	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.52383
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17863
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.868259
COPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45468
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_13922_KO_PPARGC1A_SRP314654	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.8463
CAS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76324
Perturb_15254_KI_E2f1_SRP217336	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.31181
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-SJXC-0426-SM-2XCFH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12162
Perturb_9855_KD_MSI2_SRP096137	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.09018
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4706-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal retina pigment epithelium morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_15562_KO_SLFN11_SRP327912	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.29844
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1332
Sclera	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.99
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.21697
biological regulation	GO Biological Process Annotations 2015	1.0	null
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cerebellar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08091
Perturb_6622_KD_NFE2L2_SRP158498	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.41218
Podoconiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.447
RFXAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47476
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.840967
melanocytes	GeneRIF Biological Term Annotations	1.0	null
melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.316456
c-MYC_KD_GDS2526_110_human_BT-474 BREAST CANCER cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MT-ND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63426
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34598
Perturb_12666_OE_GFP_SRP308919	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.13221
NCI-H226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11201
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
skin	HPA Tissue Gene Expression Profiles	1.0	2.22095
CTCF-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Xanthine dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.783
TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE144500_8_v_2_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_8059_KD_IGF2BP3_SRP094100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.0226
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839898
Perturb_8055_KD_IGF2BP3_SRP094100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.0205
TTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41177
Albinism	DisGeNET Gene-Disease Associations	1.0	null
trans-golgi network membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Perturb_4695_KD_Srsf3_SRP059321	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.42129
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35211
ZYG11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08484
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.026
BORCS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08944
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.342
CNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01411
abnormal hair shaft melanin granule shape	MPO Gene-Phenotype Associations	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.839898
photoreceptor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.245807
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
Perturb_14921_Mut_Atxn3_SRP155020	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.66835
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00988
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.14916
Medial geniculate complex, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27897
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7143
SOX9-26525672-CHIP-SEQ-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.103723
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.476
trans-Golgi network membrane	GO Cellular Component Annotations 2023	1.0	null
NCIH2110	DepMap CRISPR Gene Dependency	1.0	5.98092
Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65557
Perturb_4989_KO_Ythdc1_SRP212677	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.82495
KDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64892
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4763-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78041
NPTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27792
SPARC	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12202500-43018_2025_963_MOESM14_ESM.xlsx-ED_Fig_3i_ref_markergenesetl-Tirosh_MITF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TMMY-1126-SM-4DXSX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.708
TREX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90668
Cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.333
FCN2	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
Perturb_5795_KO_Stat3_ERP105170	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Iris color (a* coordinate)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
VANGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83184
CFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56772
DU4475	DepMap CRISPR Gene Dependency	1.0	5.31118
mantle zone of r1Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04711
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.538506
vesicle	GO Cellular Component Annotations 2015	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4BB-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE161064,GSE161065_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
haplotype	GeneRIF Biological Term Annotations	1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1229
HCC366	CCLE Cell Line Gene CNV Profiles	-1.0	-2.76822
ion transport	GO Biological Process Annotations 2015	1.0	null
abnormality of skin morphology	GWASdb SNP-Phenotype Associations	1.0	0.717991
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
largeintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.844548
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_11511_KD_Fbxo22_SRP170074	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.09274
Perturb_15291_OE_Tp73_SRP134969	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.70014
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.829831
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.58317
Perturb_5128_KD_Med4_SRP325525	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.25079
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.862624
Perturb_15441_KD_TMPOAS1_SRP273203	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_2352_KD_CTBP1_SRP072302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.96513
Perturb_13359_KD_Foxf2_SRP137807	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.75771
H2BC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77795
Lung squamous cell carcinoma_LUSC_TCGA-22-1005-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A1H6-01B-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13380_KO_CTIP2_SRP150394	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.73733
Perturb_13896_KO_TLR3/MYD88_SRP332441	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.25552
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_13611_KD_Puf60_SRP342713	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.56648
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041125
Granular lamina of the cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26198
abnormal retina morphology	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_5660_KO_ID2_SRP336141	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.69189
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.95511
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.48522
RSAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28847
SMAD4-21741376-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHU-1326-SM-4E3K7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06747
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10295
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y0-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-22343733-PBMC-HUMAN-BONEMARROW	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59091
Perturb_5183_KD_Ssrp1_SRP094584	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Secondary motor area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19613
Perturb_8291_KD_RRP9_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.26311
JHUEM1	DepMap CRISPR Gene Dependency	1.0	4.9044
Pharyngeal tooth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.651
Perturb_6404_KO_ERBB_SRP118937	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.76989
PBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29413
inferior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.878482
LS 180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18901
Eye	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
c3pv	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.03
Perturb_4152_KO_Chd8_SRP165973	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.51167
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2303_KD_BRCA2_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.196
cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
PMC2700213__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Lung adenocarcinoma_LUAD_TCGA-55-8085-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92497
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.919559
Perturb_5221_KO_Zfp57_SRP173610	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.09965
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043474
UCKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16391
layer 3 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89718
RFX7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4195
GNPTG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02788
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3279
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chloride channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.928
GSE254517_1_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_8_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_6598_KO_DRICH1_SRP181645	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.40717
Mastigoneme	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.635
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04456
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
ocular albinism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.75958
Lung adenocarcinoma_LUAD_TCGA-91-A4BD-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
monoatomic ion transport	GO Biological Process Annotations 2023	1.0	null
GSE220520_5_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_8920_KD_P300_SRP256204	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.21889
GSE90821_3_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Feather rachis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.8333
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17758
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34042
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24948
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.63274
core part of DTg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36749
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3606
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.449194
Perturb_6434_KD_HOXA10AS_ERP131886	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.83225
Primary somatosensory area, mouth	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06947
Lactose intolerance	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.559
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24923
Perturb_13325_KD_Klf8_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.67544
Lung squamous cell carcinoma_LUSC_TCGA-52-7809-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100428_TCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0732
GTEX-TMMY-1726-SM-4DXTD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_7429_KO|KD_RBFOX2|HNRNPM_SRP068106	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.19535
PMC5918774-13287_2018_864_MOESM2_ESM.xls-sheet-hREPC_AND_AF_MSC_AND_UM51_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
individuals	GeneRIF Biological Term Annotations	1.0	null
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.90063
GSE132948,GSE132949_4_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58509
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.884128
UBE2G2	Hub Proteins Protein-Protein Interactions	1.0	null
INMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27823
GTEX-Q2AI-1726-SM-2S1PZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_12159_OE_TCF7_SRP144189	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.72449
GTEX-UJHI-1226-SM-4IHLR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_2329_KD_SF3B5_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.72454
Perturb_5653_KD_EWSR1_SRP117628	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.1158
Chl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.852
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.099
GSE126402_2_v_7_tal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_4717_KO_Hnrnpu/Trp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.972867
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59326
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	5.0
NLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51904
CENPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29808
GRIN2C	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_17642_OE_YAP_SRP298391	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.71271
GSE135030_11_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.165
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Color blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.36
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
SNU1214	CCLE Cell Line Gene CNV Profiles	1.0	1.7619
Perturb_8507_KO_Gata4_SRP277626	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.15749
Pectoral fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.276
SMAD4-21741376-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6973
Perturb_8670_KO_SETD2_SRP291759	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.62371
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9446
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83775
SMARCA4	ChEA Transcription Factor Targets	1.0	null
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
PHOX2B-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_13431_KO_Hsf1_SRP263204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.46747
Perturb_14093_KD_HDAC1_SRP199194	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.05739
Stratum granulosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
Eye-limbal stromal cell	Tabula Sapiens Gene-Cell Associations	1.0	0.147238
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33811
GSE139911_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34005
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20231
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.916988
Perturb_81_KD_CENPA1_SRP187530	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.39264
CLIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06568
abnormality of the macula	GWASdb SNP-Phenotype Associations	1.0	0.808534
PMC12068594-pgen.1011693.s007.xlsx-MCR_vs_FCG_chr-gene_id_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.434
GSE132948,GSE132949_2_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.03891
Perturb_13072_KO_Cry2_SRP091906	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.75539
HELA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40785
Renal glycosuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850295
Perturb_4726_KO_Irx3_ERP116672	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-NPJ8-0326-SM-2D7VV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.40568
BANF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53558
Perturb_17691_KD_MDMX_SRP393452	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.70402
Perturb_7232_KO_ADIPOR2_SRP285935	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.3519
PIGG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98229
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73S-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5413_KD_PER2_SRP049409	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.35184
Perturb_8460_KO_IFNLR1_ERP121014	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.08743
Perturb_13786_OE_IL10RB_SRP329434	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.875
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RGS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55022
NCIH1869	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62955
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMRCLCD	CCLE Cell Line Gene CNV Profiles	1.0	1.84469
Cortical amygdalar area, anterior part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13438
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_4719_KO_Trp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Perturb_467_KD_ADAR1/ADAR2_SRP253895	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
ZNHIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76061
melanosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.41699
Perturb_14615_KO_MTAP_SRP186070	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94576
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3375
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05796
NCIH2122	CCLE Cell Line Gene CNV Profiles	1.0	1.73349
cholesterol	GeneRIF Biological Term Annotations	1.0	null
GTEX-SNMC-0526-SM-4DM69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Prostate adenocarcinoma_PRAD_TCGA-KC-A7F6-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_16537_KO_Lsd1_ERP114763	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.13382
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
TRAIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46739
Entorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04101
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_15750_KO_Zfp36l1_SRP285762	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.49104
Perturb_548_KO_SA2_SRP201842	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.86872
GSE137144_5_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
KHK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44642
craniofacial phenotype	MPO Gene-Phenotype Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AU-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861977
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.875262
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Perturb_5539_KO_Fh1_ERP138019	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.29048
Perturb_3620_KO_SMARCA4_SRP127343	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.2229
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48401
Perturb_11692_KD|OE_SF3A3|MYC_SRP253943	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.0284
abnormal coat appearance	MPO Gene-Phenotype Associations	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1475
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.073114
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MTMR14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08842
Perturb_6529_KO_YAP1/WWTR1_SRP212224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.52622
abnormal retinal layer morphology	MPO Gene-Phenotype Associations	1.0	null
Perturb_18281_KO_Ndp_SRP182592	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Perturb_7966_OE|KO_MPL_SRP287959	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.28454
melan-a cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.303
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_1682_KO_Nox4_SRP356837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.4255
Glottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.929879
Perturb_5170_KD_Rpap1_SRP071014	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.17781
ENSG00000284691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0194
LUDLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.48224
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39494
Perturb_3727_OE_Fut4_SRP242022	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.06222
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7467
Perturb_8973_KD_RBL1_SRP218370	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.59048
ACTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893711
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78K-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-6560-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848861
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25992
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96966
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38637
CAL-148	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO741	CCLE Cell Line Gene CNV Profiles	1.0	2.07863
PMC8814143-41419_2022_4530_MOESM12_ESM.xlsx-up_ZNF32_vs_Vector-Unnamed_1_ZNF32	Rummagene Transcription Factor Associations 2026	1.0	null
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.060002
GSE144115_2_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZFYVE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93976
PMC12202500-43018_2025_963_MOESM14_ESM.xlsx-ED_Fig_3i_ref_markergenesetl-Rambow_MITF_targets_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF660	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34856
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.84862
Lung adenocarcinoma_LUAD_TCGA-86-8673-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37336
urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HSPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27762
potassium ion transport	GO Biological Process Annotations 2015	1.0	null
Perturb_17574_KO_Airn_SRP157112	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.07812
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892985
GSE167886_2_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9314667-Table_1.xlsx-Regulons-MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061491
SMAD4	ChEA Transcription Factor Targets	1.0	null
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42817
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.817976
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.982855
BALL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99607
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.850295
Perturb_7620_OE_OspC3_SRP368098	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.4065
Perturb_15275_OE_Foxa1_SRP189075	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
negative regulation of secondary metabolite biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Perturb_7531_KO_NBDY_SRP250282	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.42169
Perturb_10660_KD_Urod_SRP226321	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.0139
Perturb_3940_KD_IRGM_ERP122050	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.00265
ITGB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79068
Perturb_11172_KO_Klf15_SRP186285	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.93747
Amyotrophic lateral sclerosis type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
Skin, hair and eye pigmentation (multivariate analysis)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	10.0
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04035
GSE207914_1_v_7_nudt7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.557
Perturb_14938_KD_Ptbp1_SRP053095	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.0376
GSE122067_3_v_0_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PARL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25099
Perturb_7266_OE_OspC1_SRP368098	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.77859
Photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.197
Perturb_18444_KD_YAP1/WWTR1/STING1_SRP303519	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.11596
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
SELENOI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01229
darker	GeneRIF Biological Term Annotations	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.06188
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleotide	GeneRIF Biological Term Annotations	1.0	null
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.851774
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Swim bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
SF539	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dense body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.647
GINS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97259
oa1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.505
superficial stratum of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07579
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.70541
Perturb_10253_KO_WT1_ERP126063	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.05683
GSE201270,GSE201272_0_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898242
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.5043
abnormality of eye movement	HPO Gene-Disease Associations	1.0	null
liver	HPA Tissue Gene Expression Profiles	-1.0	-1.38224
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
a2780cis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.174
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03705
ZNF320	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25146
autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.0774
Forearm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.142
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07076
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986315
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.46012
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25425
nckx2	GeneRIF Biological Term Annotations	1.0	null
negative regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
Perturb_9767_KO_Cdk1_SRP287303	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.66046
GSE139239_2_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1844
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1918_KO_Irf5_SRP186268	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.65847
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.092809
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.2487
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01122
Lens fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.576
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.55266
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.870555
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	0.411248
Perturb_13255_KD_Paf1_SRP083772	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.50133
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20145
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869176
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00287
Perturb_15980_KO_Tdrd6_SRP050899	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.33202
Metatarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
TRMT61B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47807
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.876
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.426265
H2795	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.17351
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.917183
Perturb_17639_OE_WWTR1_SRP298391	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.90083
intermediate stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29165
variation	GeneRIF Biological Term Annotations	1.0	null
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GSE180200,GSE180201_2_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_9449_OE_ALS/FUS_SRP297132	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.0653
Perturb_1271_KO_Adar_SRP132963	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.94874
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39587
SNU1272	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57163
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7221
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.706598
GSE224969,GSE224971_3_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MALME-3M cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.522
PRKCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58672
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39772
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.04376
Lung adenocarcinoma_LUAD_TCGA-55-7913-01B-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE238005_5_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MTIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91069
Perturb_11846_KO_Tmem106b_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.43925
CALHM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10763
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.845
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21967
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72654
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02421
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95958
Oculocutaneous albinism type III	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
Defective SLC24A5 causes oculocutaneous albinism 6 (OCA6)	Reactome Pathways 2024	1.0	null
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5377
dorsolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46533
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868727
Perturb_289_KO_PHF8_SRP399627	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.05372
PPP1R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96708
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.14935
Perturb_13953_OE_lncNR2F1_SRP179994	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.75603
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26929
HH	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94016
Perturb_665_KO_Myc_SRP093784	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.03343
carrying	GeneRIF Biological Term Annotations	1.0	null
Perturb_1344_KD_ARID1A_SRP336358	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.8239
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.862044
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
ovary	HPA Tissue Gene Expression Profiles	-1.0	-0.883161
SKNFI	DepMap CRISPR Gene Dependency	1.0	2.3336
Perturb_1680_KO_Nox4_SRP356837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.9325
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906307
Perturb_3972_KD|Mut_SFPQ|BRAF_SRP258593	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.65377
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20131
Perturb_2049_KO_Trp53_DRP003641	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.25606
Perturb_14156_KO|KD_KBTBD4|RCOR1_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
lankans	GeneRIF Biological Term Annotations	1.0	null
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35486
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.9752
Perturb_11531_KD_THOR_SRP121007	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.8377
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35211
GRAMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66803
496100563_PCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07441
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968194
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.64088
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.03976
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40548
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.988685
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3187
Perturb_20_OE_Smarca5_SRP217699	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.1466
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52616
AGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82144
SLC-mediated transmembrane transport	Reactome Pathways 2024	1.0	null
GH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61544
PLAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84554
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056625
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.964491
outer CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.74475
Perturb_1683_KO_Nox4_SRP356837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.9234
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64061
ZFX_02_172	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.16993
skmel30	HPA Cell Line Gene Expression Profiles	1.0	2.7193
CCDC152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61193
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZKSCAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84941
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52155
alphamsh	GeneRIF Biological Term Annotations	1.0	null
Ubp3-Bre5 deubiquitination complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.783
GRIN2D	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_4779_KD_Trim24/Trp53_ERP016337	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.84497
natural	GeneRIF Biological Term Annotations	1.0	null
Perturb_2338_KD_MUC1C_SRP300048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.71
CDK4_knockdown_133_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.52277
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.39
TLCD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16784
ZFP92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31804
Lung adenocarcinoma_LUAD_TCGA-95-7043-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184902_4_v_1_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FZD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77944
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044787
abnormality of the skin	GWASdb SNP-Phenotype Associations	1.0	0.291605
single-organism process	GO Biological Process Annotations 2015	1.0	null
Perturb_17467_KO_Dmd_SRP278118	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.73145
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AY-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Geniculate group, dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15939
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.220424
posteroventral (inferior) parietal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34198
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0441
MALME3M	DepMap CRISPR Gene Dependency	1.0	7.76173
membrane	GO Cellular Component Annotations 2015	1.0	null
pigment granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.38738
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A263-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12289
outer CP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.904474
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25059
Thalassemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
APTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87012
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.482104
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.691
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6278
regulation of biosynthetic process	GO Biological Process Annotations 2015	1.0	null
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.65145
Perturb_7456_KO_DHX36_SRP120501	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.85687
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38108
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_4985_KO_Ythdc1_SRP212677	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.76492
platelet dense granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.547297
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18598
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877716
Perturb_12268_KO_CECR1_SRP255026	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.43928
excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_7599_KO_CTNNB1_ERP109990	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.856
Plasmodium vivax malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
TBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.747
periventricular stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41921
GTEX-OIZH-0626-SM-3NB1L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
trans-Golgi network membrane	GO Cellular Component Annotations 2025	1.0	null
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69801
Perturb_2771_KD_IRX6_SRP072302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.63536
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
Disorders of transmembrane transporters	Reactome Pathways 2024	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.982467
GSE134191_3_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4351-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Platelet storage pool deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.791
PMC6607928-iovs-60-07-32_file_S11.xlsx-no_change_NRL_mutants-human_gene_ortholog_NRL	Rummagene Transcription Factor Associations 2026	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZE-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.1553
PPM1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22435
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896501
superficial stratum of InsCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25992
RGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19476
L-428	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAL72	DepMap CRISPR Gene Dependency	1.0	2.27491
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Frontal pole, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08971
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Melanosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.28
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Familial melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.404
GCIY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_7503_KD_SUDS3_SRP194754	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.08738
Melanoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.39
CPCN	CCLE Cell Line Gene CNV Profiles	1.0	1.34477
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Kidney	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE205070_1_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7742
NCI-H1770	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.81683
south	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
assembly	GeneRIF Biological Term Annotations	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Enamel organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.830334
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_478_KD_PPARGC1A_SRP278736	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.36141
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07678
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43095
Perturb_1685_KO_Nox4_SRP356837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.5922
TRMT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8261
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I5-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Eye color	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.6
TBCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77542
RFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29228
pigmentation phenotype	MPO Gene-Phenotype Associations	1.0	null
CAMK2G	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-A59Q-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Platelet dense granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.021
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
Perturb_11534_KD_THOR_SRP121007	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.88083
Perturb_18120_KO_Tfap2b_SRP196877	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.58665
GSE165682_2_v_5_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23937
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KCL-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ARHGEF10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11364
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
GSE180200,GSE180201_12_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985358
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00912
Hair color	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.8
hsa-miR-544	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
hair follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.7146
encoding	GeneRIF Biological Term Annotations	1.0	null
METAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77834
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58218
Perturb_13613_KD_Puf60_SRP342713	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
increased grip strength	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_16779_KO_Tbet_SRP120994	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.45898
Perturb_16923_KO_miR26a1/miR26a2/miR26b_SRP216065	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.67864
EIF3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00877
Perturb_4816_KO_Apex1_SRP193096	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.41593
ZNF536	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3798
Perturb_12232_KD_SNRPA1_SRP291357	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.30157
Perturb_2717_KO_TET1_SRP110516	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.4999
Perturb_16811_OE_HNF1A/FOXA3/PROX1_SRP167105	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.9886
periventricular stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30696
alleles	GeneRIF Biological Term Annotations	1.0	null
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
CNNM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33087
melanoma cell line	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Kidney Failure, Chronic	DisGeNET Gene-Disease Associations	1.0	null
Perturb_15521_OE_proL1_SRP277452	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.3478
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.832927
Perturb_5305_KO_Dnmt1/Dnmt3a/Dnmt3b_SRP101434	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.18268
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49548
distinguishes	GeneRIF Biological Term Annotations	1.0	null
Perturb_2778_KD_ZNF589_SRP072302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.21075
RUNX1	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_18494_Mut_Ercc2_SRP286486	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Perturb_11316_KO_Noct_SRP120584	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.56109
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847945
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZZ-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sodium ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
LAMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45087
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
NCIH1581	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44892
PMC11178519-CTM2-14-e1723-s002.xlsx-STab_19a_HuCCT1_PBX1-res_HuH28_PBX1_wt_log2FC1_pdaj0_PBX1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13265_KO_chr3_SRP162484	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Perturb_12703_KO_LIPA_SRP310406	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.86068
Orbital area, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08541
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.554
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.846194
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.879047
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51136
Cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2523
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.905266
SLC19A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42498
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17151
Pterinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.643
anterior pretectal nucleus, dorsal superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44979
Perturb_12182_KD_PALB2_SRP015361	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.29013
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17117
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52996
mRNA_SMAD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Xanthophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.702
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0084
Invertebrate mandible	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.519
Perturb_9295_KO_Parp1_SRP254965	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.16262
a111t	GeneRIF Biological Term Annotations	1.0	null
clearly	GeneRIF Biological Term Annotations	1.0	null
LCMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99876
TENT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04104
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
solute:cation antiporter activity	GO Molecular Function Annotations 2015	1.0	null
Perturb_4939_KD_Etv5_SRP111429	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.41493
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RPL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65988
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	0.896403
496100335_PCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13524
FGD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17784
abnormal ear pigmentation	MPO Gene-Phenotype Associations	1.0	null
Perturb_13233_OE_Rnaseh1_SRP056871	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.72297
GSE132948,GSE132949_0_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_4710_KO_Sox9_ERP109172	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.23451
encoded	GeneRIF Biological Term Annotations	1.0	null
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1275
Perturb_4838_OE_Gfi1_SRP220284	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.55628
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-P53_DN_V1_DN-Ensemble_gene_ID_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
TSEN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22483
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
PTRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02726
Perturb_13601_KD_YAP1_SRP337871	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.1692
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04945
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
HOXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57247
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
monovalent inorganic cation transport	GO Biological Process Annotations 2015	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A82F-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4929_OE_KLF17_ERP131758	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.68988
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09622
GSE171179,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
calcium ion homeostasis	GO Biological Process Annotations 2023	1.0	null
Perturb_2769_KD_FOXQ1_SRP072302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.25796
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.882701
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928311
Adrenocortical carcinoma_ACC_TCGA-OR-A5LE-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SELENOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75841
Perturb_737_KD_CHD4_SRP123294	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_5140_KO_Rn7sk_ERP002405	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.38478
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.9056
SKNFI	CCLE Cell Line Gene CNV Profiles	1.0	1.56988
macular degeneration	GAD Gene-Disease Associations	1.0	null
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.928611
C2CD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42816
abnormal coat/hair pigmentation	MPO Gene-Phenotype Associations	1.0	null
GSE137144_4_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83845
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34041
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38244
CEP152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09932
ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.124449
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.9919
greek	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fatty Liver	CTD Gene-Disease Associations	1.0	1.27626
PMC9172632-pnas.2107006119.sd01.xlsx-Gene_sets_for_zscores-MITF_targets_Cheli_et_al_2009_Human_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_9407_KD_GATA6AS_SRP279802	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.45015
higher	GeneRIF Biological Term Annotations	1.0	null
Perturb_15995_KD_LUCAT1_SRP221619	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.89397
Scalp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.153
abnormal ciliary body pigmentation	MPO Gene-Phenotype Associations	1.0	null
CYB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57733
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10579
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61408
Perturb_2728_KD_NEK2_SRP231163	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.1036
SMURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3517
GSE239578_5_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_11312_KO_Bmal1_SRP153814	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.39454
GTEX-S4Q7-1626-SM-3K2AE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.938588
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.2222
GSE166169_1_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
single	GeneRIF Biological Term Annotations	1.0	null
solute:potassium antiporter activity	GO Molecular Function Annotations 2025	1.0	null
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04808
NCIH2882	DepMap CRISPR Gene Dependency	1.0	3.03441
COLGALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62948
CHAGOK1	CCLE Cell Line Gene CNV Profiles	1.0	1.46828
Perturb_9100_KD_Tfpi_SRP312891	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	17.6861
Taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46592
Entorhinal area, medial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03011
Rectum adenocarcinoma_READ_TCGA-DC-6682-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4520_OE_Jarid2_SRP281895	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.02312
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040597
RPL35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51663
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.38428
Feather barbules	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.973
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.274101
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3YL-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07012
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_3619_KO_SMARCA4_SRP127343	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.9704
Perturb_13067_KO_Ube3d_SRP373803	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.3823
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.68173
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
layer 4 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18363
Lung squamous cell carcinoma_LUSC_TCGA-21-1071-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAMK2A	Pathway Commons Protein-Protein Interactions	1.0	null
ANKRA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39644
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7807
Perturb_7494_KD_DICER1_SRP186271	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.61716
GSE239578_2_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUZC-0426-SM-4BOPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12382
admixed	GeneRIF Biological Term Annotations	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
OB outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3719
F9	Pathway Commons Protein-Protein Interactions	1.0	null
solute:potassium antiporter activity	GO Molecular Function Annotations 2023	1.0	null
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	2.10766
sensory system disease	GWASdb SNP-Disease Associations	1.0	0.112324
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_12497_KD_TP53_SRP364608	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.49489
nystagmus	HPO Gene-Disease Associations	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.55667
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02546
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Perturb_532_KD_TCF4_SRP234742	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.7842
Oculocutaneous albinism	ClinVar Gene-Phenotype Associations 2025	1.0	null
496100403_TCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12137
Perturb_2978_KD_NCOR1_SRP319239	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.57682
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.887473
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_9313_KD_HOTAIR_SRP378143	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.245
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7558
Perturb_8245_KD_TIA1_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.7118
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1856
CMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_1917_KO_Arhgef2_SRP186268	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.74
GTEX-QEL4-1526-SM-447AB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843785
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94816
JHH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
golgi apparatus part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.067335
Cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
GTEX-UTHO-2426-SM-4JBHD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Skin/hair/eye pigmentation, variation in, 4	ClinVar Gene-Phenotype Associations	1.0	null
periventricular stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34768
brain	GTEx Tissue Gene Expression Profiles	1.0	1.26771
Antler	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.920807
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00788
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3907
Perturb_5871_KD_Nudt21_SRP336206	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.88902
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_65_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87662
Perturb_15753_KO_Ezh2_SRP096837	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
ocular albinism	MPO Gene-Phenotype Associations	1.0	null
decreased fasting circulating glucose level	IMPC Knockout Mouse Phenotypes	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19066
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61108
MYL12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23899
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.853613
Epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.477
sequencing	GeneRIF Biological Term Annotations	1.0	null
Perturb_13298_OE_Pik3ca_SRP173204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.80869
Perturb_14925_OE_HsATXN3_SRP155020	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.96331
lateral habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.99126
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.163523
ARHGEF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13106
SNU668	DepMap CRISPR Gene Dependency	1.0	3.2124
GTEX-PWN1-0626-SM-48TDT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
U937	CCLE Cell Line Gene CNV Profiles	1.0	2.27147
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16606
PDIA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19289
Perturb_2425_KD_BNC2_SRP072302	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.55901
INAFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16145
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19808
SNU119	CCLE Cell Line Gene CNV Profiles	-1.0	-2.72155
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
NCIH358	CCLE Cell Line Gene CNV Profiles	1.0	1.9543
Cellular bud neck contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.739
RIMKLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73607
Perturb_9063_KD_NANOG_SRP100928	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.43
Perturb_2237_KO_Malat1_SRP193997	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.55076
TBL1Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52692
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Skin pigmentation	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.35229
periventricular stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35801
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Hair follicle inner root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.327205
Ocular motility disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.521
Vascular Diseases	CTD Gene-Disease Associations	1.0	1.04239
External ectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.685
HNRNPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44762
PMC9314667-Table_1.xlsx-Regulons-MITF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
ROCK_INHIBITION_GDS3944_461_mouse_Forebrain astrocytes - 2 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Perturb_499_KD_PKR/BRF1_SRP382324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.43956
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A468-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
transgolgi	GeneRIF Biological Term Annotations	1.0	null
Perturb_15085_OE_miR182_SRP325701	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.18784
Acute contagious conjunctivitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.177
Perturb_8769_KD_SERPINA1_SRP302345	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.8692
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3954
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A2C7-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	Reactome Pathways 2024	1.0	null
Perturb_2697_KO_ADIPOR1_SRP089784	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.27619
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neural crest	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.61699
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3155
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2318
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
heterogeneous	GeneRIF Biological Term Annotations	1.0	null
trans-Golgi network membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ANLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58428
stratum corneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.503141
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.2671
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976144
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63168
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFJO-1026-SM-3GIKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5556
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7198
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.00983
abnormal melanosome morphology	MPO Gene-Phenotype Associations	1.0	null
JURL-MK1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02044
Choroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.534
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3341
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2246
CIAO2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45926
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4774
GSE147943_5_v_1_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.38942
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9786
Vocal fold	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.791
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.4408
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3932
SF3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0109
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.881755
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lower epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.792
Iris color (b* coordinate)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.809691
Lung adenocarcinoma_LUAD_TCGA-J2-A4AG-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06155
Sense organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_11829_KO_Pxdc1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.13482
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
lighter	GeneRIF Biological Term Annotations	1.0	null
FCN3	Pathway Commons Protein-Protein Interactions	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.05573
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01466
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
trans-golgi network	GO Cellular Component Annotations 2015	1.0	null
myocardial infarction	GWASdb SNP-Phenotype Associations	1.0	1.29015
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A431-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844681
59M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.59192
Perturb_7627_KD_HNRNPL_SRP129007	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.63382
Perturb_937_KD_Smndc1_SRP337256	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.8497
VCAP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_8492_KD_Mir34a_SRP133851	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.9478
Syndromic microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	2.06566
GSE224969,GSE224971_0_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.554876
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.970279
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
regulation of secondary metabolic process	GO Biological Process Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A1DG-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MASP1	Pathway Commons Protein-Protein Interactions	1.0	null
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27621
GTEX-QDVJ-0726-SM-48U1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HE-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.990016
Lung squamous cell carcinoma_LUSC_TCGA-94-7943-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal dermal pigmentation	MPO Gene-Phenotype Associations	1.0	null
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.64157
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
negative regulation of biosynthetic process	GO Biological Process Annotations 2015	1.0	null
NAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05664
Body Mass Index	DisGeNET Gene-Phenotype Associations	1.0	null
hypopigmentation	MPO Gene-Phenotype Associations	1.0	null
Perturb_3127_KO_Stxbp5l_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.43927
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.95129
Perturb_15465_OE_ETV4_SRP402451	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.35007
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2152
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29502
c16	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.819
Ink gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.651
Sodium/Calcium exchangers	Reactome Pathways 2024	1.0	null
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60765
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913957
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.21409
Olfactory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14386
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE137144_5_v_7_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110440_2_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.336081
inner CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.870938
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55592
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.13491
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
MEG-01 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18871
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32552
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GM-06B-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JW-1326-SM-4DM5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_12905_KD_MDC1_SRP313175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.96105
NEUROG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44755
2-iminoacetate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.671
Sleep disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.656
Perturb_10599_OE_Vcp_SRP214099	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.68112
DNAJA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83046
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986976
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_8239_KD_RECQL_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.18707
Perturb_5126_KD_Med30_SRP325525	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.62459
GTEX-O5YV-1026-SM-3LK72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Nystagmus	DisGeNET Gene-Phenotype Associations	1.0	null
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.91873
HARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25295
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3028
Cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
Mitotic actomyosin contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.737
Perturb_12522_KD_MUC1_SRP381930	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.89102
Face	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.84
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52911
BCL6-25482012-CML-JURL-MK1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
abnormal hair shaft melanin granule morphology	MPO Gene-Phenotype Associations	1.0	null
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
IPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66778
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06577
Lung squamous cell carcinoma_LUSC_TCGA-85-A4CL-01A-41R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.875748
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53582
BLOC-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.846
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986315
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15793
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
PMC8494348-pone.0257161.s002.xlsx-only_OXT_NOT_ext-OXT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Melanoma	DisGeNET Gene-Disease Associations	1.0	null
Pigment granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.277
variant	GeneRIF Biological Term Annotations	1.0	null
negative regulation of melanin biosynthetic process	GO Biological Process Annotations 2015	1.0	null
Albinism, Oculocutaneous	DisGeNET Gene-Disease Associations	1.0	null
autosomal dominant inheritance	HPO Gene-Disease Associations	1.0	null
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57321
GSE180200,GSE180201_12_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
sri	GeneRIF Biological Term Annotations	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NFYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22722
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GSE151829,GSE151831_7_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JZ-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
monoatomic cation transmembrane transport	GO Biological Process Annotations 2025	1.0	null
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43U-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_9_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HES4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66291
substantia innominata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.922496
Perturb_7968_OE|KO_MPL_SRP287959	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.03619
GSE133691_1_v_3_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ameloblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.865
superior parietal lobule, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.44845
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6925
potassium ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Sodium	HMDB Metabolites of Enzymes	1.0	null
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051784
Perturb_13756_KD_KLF4_SRP233218	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.1249
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48134
GTEX-X638-0008-SM-47JZ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
MAF_01_165	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.5907
CAPAN2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32035
GSE242290_1_v_8_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Fundus dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
pigment	GeneRIF Biological Term Annotations	1.0	null
TIMM50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45318
MECOM-23826213-KASUMI-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6212-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
origin	GeneRIF Biological Term Annotations	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06739
Perturb_17880_KO_Hhex_SRP313523	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.44679
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.30216
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_2_AP2_Down_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87314
Perturb_13238_KO_Flcn_SRP126727	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.13364
H4K20me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_13077_KO_Cry2_SRP091906	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.78269
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_4953_KO_Zbtb2_ERP125292	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.82824
Coloboma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
GSE183413_0_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IMR32	DepMap CRISPR Gene Dependency	1.0	7.15943
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9526
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_4767_KO_Kap1_SRP065215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.9189
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_5024_KO_Oct1_SRP080768	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.11746
Perturb_2873_Mut_KRAS_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.54822
Perturb_9388_KO_IRF1_SRP148971	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.18642
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.73083
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03835
Perturb_16957_KO_Drp1_SRP173900	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.26258
ZFAND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59784
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IZUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16427
carcinoma, basal cell; carcinoma, squamous cell; melanoma; skin neoplasms	GAD Gene-Disease Associations	1.0	null
Perturb_8818_KD_INTS12_SRP073445	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.45981
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847112
Perturb_80_KD_CENPA1_SRP187530	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.1713
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24087
trunk	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HUH6	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07508
STAT4-19710469-TH1 cell mouse-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Arsenic	CTD Gene-Chemical Interactions	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
degeneration of macula and posterior pole	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.175411
GSE184902_3_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71529
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.67591
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.877037
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_12904_KD_FOXA1_SRP313175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.6778
calcium ion transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2584
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nckx5	GeneRIF Biological Term Annotations	1.0	null
Perturb_3081_KO_Dock11_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.08511
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_9695_KO_GPNMB_SRP382180	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.58842
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.843008
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05324
OLIG2	ChEA Transcription Factor Targets	1.0	null
homeostasis	GeneRIF Biological Term Annotations	1.0	null
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17657
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0637
oculocutaneous	GeneRIF Biological Term Annotations	1.0	null
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.552
Perturb_14484_KO_Ubc9_SRP202561	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.64459
primary auditory cortex (core)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08498
Photoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.6
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.88238
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.49
MRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63443
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
U266B1	CCLE Cell Line Gene CNV Profiles	1.0	1.70079
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985458
xanthophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.756799
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.072216
TP53RK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03689
Perturb_8486_OE_PLXNB2_SRP282509	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.34773
Arthrogryposis multiplex congenita-6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.389
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901444
PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	1.0	3.96859
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4718-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.82163
Sodium/Calcium exchangers	Reactome Pathways 2014	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.38428
abnormal melanosome morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_10330_KO_Dnmt3a/Dnmt3b_SRP214596	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.50567
pa111t	GeneRIF Biological Term Annotations	1.0	null
NCIH28	DepMap CRISPR Gene Dependency	1.0	4.66919
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09572
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6346
GTEX-X8HC-2826-SM-46MWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50992
Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Adventurousness	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
IKBKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24152
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_12339_KD_SAM68_SRP230812	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.82421
OCUG1	DepMap CRISPR Gene Dependency	1.0	4.44811
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
wc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3839
PRDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70192
KLHDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22813
abnormal retina morphology	MPO Gene-Phenotype Associations	1.0	null
SNU1033	DepMap CRISPR Gene Dependency	1.0	2.40101
Skin melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.519
Rectum adenocarcinoma_READ_TCGA-AF-5654-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Foveal Hypoplasia (Finding)	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-X5EB-1926-SM-4E3IW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99385
Hi-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.776
allele	GeneRIF Biological Term Annotations	1.0	null
GSE135350_2_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44066
Optic cup	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.26527
cytoplasmic vesicle	GO Cellular Component Annotations 2015	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27073
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87377
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
Tapetum lucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACTN2	Pathway Commons Protein-Protein Interactions	1.0	null
KLF4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BLOC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.82
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.895574
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16562
GTEX-RUSQ-0826-SM-47JWW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
pigment granule	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
reduced	GeneRIF Biological Term Annotations	1.0	null
Perturb_14125_KO_TP53/CDKN2A_SRP258861	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.88743
Lung adenocarcinoma_LUAD_TCGA-97-8174-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13754_KD_KLF3_SRP233218	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.33123
abnormal eye morphology	GWASdb SNP-Phenotype Associations	1.0	0.134192
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874145
C9orf78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80652
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70R-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3346_KO_Sox4_SRP094461	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.71526
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45905
macular degeneration	GWASdb SNP-Disease Associations	1.0	0.918934
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Lung adenocarcinoma_LUAD_TCGA-L9-A443-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nauplius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.292
parvicellular part of Lat	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34086
PMC2694838-1471-2164-10-241-S3.xls-Sheet1-Commonly_altered_genes_by_ZNF191_overexpression_and_knockdown_ZNF24	Rummagene Transcription Factor Associations 2026	1.0	null
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26249
frontal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.66691
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.99791
wing	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.667622
Perturb_15041_KO_Klf2/Klf4_SRP095733	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.1706
HDAC1	ENCODE Transcription Factor Targets	1.0	null
TP53	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
calcium ion transport	GO Biological Process Annotations 2023	1.0	null
NCI-H3122	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_7415_KD_HNRNPC_SRP040278	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.95974
feather	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.769855
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GTEX-PLZ4-2726-SM-3P61A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Grm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.673
KDM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78139
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.896005
CYB5D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4495
Perturb_12910_KD_FOXA1_SRP313175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.96631
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ANKRD33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03805
Perturb_15657_KD_Mettl4_SRP347440	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Perturb_4488_KO_Rnu11_SRP309496	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.86747
DBT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73106
Eye color (saturation)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	4.42218
Perturb_14150_KO|KD_KBTBD4|RCOR1_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Tooth enamel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.157
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29787
Perturb_1842_KO_Ifnar_SRP371304	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.44976
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26441
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.711465
Perturb_1299_KD_Yap1/Wwtr1_SRP278830	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.87734
TAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53296
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EN-01A-21R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.159124
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.45758
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_9439_KO_Mnx1_SRP239547	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.89721
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15808
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04712
IZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08086
abnormality of skin pigmentation	GWASdb SNP-Phenotype Associations	1.0	1.89941
Perturb_5252_KO_Klf2/Snd1_SRP311785	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Golgi apparatus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
NKX6-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42483
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20274
Perturb_14625_KO_OGT_SRP146064	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.73885
Perturb_15486_KD_SIM2_SRP218853	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.52738
age related macular degeneration	GWASdb SNP-Disease Associations	1.0	0.918934
Perturb_14609_KD_SIK3_SRP118895	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.82869
Perturb_13569_KD_Crebl2_SRP214575	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.68145
CJUN-26792858-CHIP-SEQ-BT549-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hair	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.149176
Perturb_4990_KO_Ctnnb1_SRP240867	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.3355
GSE224969,GSE224971_3_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824954
Perturb_9386_KD_Pdss2_SRP300445	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.95146
Blood protein disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
layer 3 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1275
calcium ion import	GO Biological Process Annotations 2023	1.0	null
Perturb_2733_KD_BCKDK_SRP298085	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.05772
gyrus rectus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00116
PCDHB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55891
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
GSE110708_1_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QEL4-1426-SM-447AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04239
Perturb_4718_KO_Hnrnpu/Trp53_SRP331236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0