association	dataset	threshold value	standardized value
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2622
BRD-K63065496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99132
RBBP5	ENCODE Transcription Factor Targets	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BUB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00569667
FBLIM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00580447
GSE114992,GSE114993_7_v_10_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-606	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
H3K9ac_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K76701247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35469
Cardiovascular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01757
FCGRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75828
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.29672
PMC11426526-ppat.1012555.s013.xlsx-Lipid_biosynthesis_and_metaboli-PPAR_signaling_pathway_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K62833556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14885
BRD-K26766324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4204
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.913505
CRCGN017_MCF10A.WT.HP_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21699
pargyline-2265	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
uptake	GeneRIF Biological Term Annotations	1.0	null
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MDAMB157	CCLE Cell Line Gene Expression Profiles	1.0	1.55601
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_597_OE_HOTAIR_SRP342161	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.82381
BRD-K58614056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86568
BRD-K38557431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12853
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09378334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12966
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.25028
GTEX-TKQ2-1026-SM-33HB7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Longissimus lumborum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.063
HCT-116	GDSC Cell Line Gene Expression Profiles	1.0	1.83438
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.75215
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oxantel-5338	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primidone-5323	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WEY5-0926-SM-4LMI4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08506
Left atrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.043
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.62297
Carcass	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.377
CRCGN013_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09634
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.09609
BRD-K34957967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16125
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6647
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
lipid import into cell	GO Biological Process Annotations 2025	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MD MB231	BioGPS Cell Line Gene Expression Profiles	1.0	1.31046
GSE173873_12_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_SMAD4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE211126_1_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P78B-0426-SM-2I5F5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04763
MFSD2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93614
BRD-K55642725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61634
Perturb_15485_KO_TET2_SRP188574	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.68454
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A99644411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04891
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K66580188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03506
disease	GWASdb SNP-Disease Associations	1.0	0.028776
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
amikacin-5314	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K41731186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69481
GSE165916_1_v_2_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Chorion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.177
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
orbital frontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.866382
CCR6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00598203
CRCGN009_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24127
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.12819
18757322-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Syncytiotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.75
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08796
Perturb_4928_OE_KLF17_ERP131959	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.28799
PMC12354803-42003_2025_8643_MOESM2_ESM.xlsx-2w_TP63_positive-Gene_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
amygdaloid complex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20487
GTEX-S32W-2526-SM-2XCB8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1268
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867083
pontine raphe nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.894063
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.1188
BRD-K02946901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07066
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1986
MDAMB415	CCLE Cell Line Gene CNV Profiles	1.0	1.74071
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K68608492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29672
BRD-K27170250_7374280_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K69328504_L-690,488_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Iminoglycinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130396_0_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN013_HEPG2_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.24168
18787218-tableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE114992,GSE114993_1_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08488
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.948502
BRD-K70549064_EI-156_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE115328_6_v_7_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.254296
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13775
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.9619
BRD-K66963756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3639
BRD-K30467307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13919
BRD-K56032186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00871
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MO-2026-SM-33HB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10909
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Intramuscular adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.773
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7880-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869164
BRD-K63787803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32013
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Fatty acid transport protein 6	InterPro Predicted Protein Domain Annotations	1.0	null
HT1197	CCLE Cell Line Gene Expression Profiles	1.0	2.65489
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0516
BRD-K78062244_STOCK1N-27488_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-W5WG-1126-SM-4LMK4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962988
BRD-K97748753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22937
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.90231
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059824
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE173201_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ciprofibrate-6218	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Xeroderma pigmentosum group E	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0927
GSE92364_0_v_3_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
nalbuphine-2225	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
GSE245270_1_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WY7C-2626-SM-3NB2P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02972
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Perturb_14389_KD_PAX8_SRP276625	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K34297711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83427
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29552
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.085836
GSE145249_1_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
estradiol-1079	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K92158425_N-((5-chloro-1H-benzo[d]imidazol-2-yl)methyl)-2-morpholino-9-(thiophen-3-yl)-9H-purin-6-amine_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059647
BRD-K66715657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52631
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE149075_1_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
fatty acid metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K77425312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32742
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6681-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-QEG4-0426-SM-33HC3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16386
RMND5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35388
RIDDLE syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08265
BRD-K09416995_lovastatin_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SUZ12_DEPLETION_GDS2445_119_human_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KZ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fibroid Tumor	DisGeNET Gene-Disease Associations	1.0	null
SUZ12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00342953
H3K27me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_14339_KD_CTCFL_SRP306444	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.56537
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25299
BICR16	DepMap CRISPR Gene Dependency	1.0	6.19833
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE143316_0_v_5_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Transport of vitamins, nucleosides, and related molecules	Reactome Pathways 2024	1.0	null
BRD-K28108927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07652
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8665548-12864_2021_8126_MOESM1_ESM.xlsx-PPAR_signaling_pathway-Unnamed_1_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHPG-0826-SM-3NMBF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50912
BRD-K71109636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13484
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5543
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38474
MFE296	CCLE Cell Line Gene Expression Profiles	1.0	1.3605
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825836
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K22940496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16418
cromoglicic acid-3475	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6329-01A-13R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.9921
PMC4029819-pone.0098069.s005.xlsx-FOXA1-Table_S4_FSS_analysis_of_FOXA1_high_versus_FOXA1_low_cases_in_ER_negative_samples_p-value_0_01_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5746105__F16	PFOCR Pathway Figure Associations 2024	1.0	null
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adenosine phosphate-5359	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3386
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-QLQ7-0526-SM-2I5G3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915558
BRD-K98758203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79213
GSE117045_1_v_2_amphetamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_2481_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K77935284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75002
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
t70-white-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.35535
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CCK81	DepMap CRISPR Gene Dependency	1.0	2.55312
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09111
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72892670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01485
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	0.862726
BRD-K79965790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33317
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7393-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-574-ZSCAN1_ZSCAN1	Rummagene Transcription Factor Associations 2026	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.29996
umbilical cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.172648
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2072
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RGS13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00647587
BRD-K93516545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36556
Trophectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.07
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K70881766_Solanine alpha_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-P4PP-0726-SM-3NM9S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30099
Perturb_6797_KD_BRD4_SRP063978	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2877-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carmustine-6914	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.926197
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903118
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066147
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76450502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33665
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A3PJ-01A-21R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1437	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Glucose Intolerance	CTD Gene-Disease Associations	1.0	1.25899
BRD-A19633847_PERHEXILINE MALEATE_JHUEM2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE168587,GSE168752_3_v_1_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111102,GSE111105_3_v_5_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEG4-1226-SM-2S1P6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20287
HMGB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01323
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heart muscle	HPA Tissue Gene Expression Profiles	1.0	0.957794
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24928
Rippling muscle disease 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
HONE-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.067
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.016
GTEX-XPVG-2826-SM-4B66J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90403
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LU-165	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K81418486_vorinostat_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GSE87412,GSE92423_3_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_9627_KD_CHD8_SRP047233	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.63782
GSE145249_1_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K41996876_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42014
BRD-K95852319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15844
disorders	GeneRIF Biological Term Annotations	1.0	null
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.25885
BRD-A63346720_Rimcazole dihydrochloride_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47635
GSE147662_2_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TEN	CCLE Cell Line Gene CNV Profiles	1.0	1.38406
GSE125211_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K33787033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25894
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13623
Sarcoma_SARC_TCGA-DX-A6B9-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899062
CHD3	Hub Proteins Protein-Protein Interactions	1.0	null
BRD-K20799008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12938
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.65851
GTEX-T6MO-1726-SM-33HB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
JHOS2	CCLE Cell Line Gene Expression Profiles	1.0	1.47508
BRD-K44067360_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_3570_KO_RAB5C_SRP285142	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.91913
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.88526
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13949
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	-1.0	-0.748764
YAPC	CCLE Cell Line Gene Expression Profiles	-1.0	-3.49496
BRD-K63587749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04283
Perturb_1434_KO_Kmt2c_SRP283007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.3247
H-89-6873	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K64753899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0078
sarcolemma	GO Cellular Component Annotations 2015	1.0	null
Hydranencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
GSE218060_7_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210101,GSE210114_0_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K38907993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72991
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09316
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K90259198_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
decreased grip strength	MGI Mouse Phenotype Associations 2023	1.0	null
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_2_TBRC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56618
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K50985475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39601
Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11061611-cd-23-0857_table_s4_suppst4.xlsx-Epithelial_F1-pEpi6_FU1_shared_basaloid_KRT15_TP63_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
GSE63048_11_v_5_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27238
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18631401-TableS3	GeneSigDB Published Gene Signatures	1.0	null
BRD-K04887706_Akti-1/2_SKMEL28_6.0_h_9.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K97624853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05812
Perturb_3358_KO_Xbp1_SRP157113	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.71867
BRD-K01067435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04669
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G4_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
Perturb_13131_KO_Kat6a_SRP126967	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
CRCGN017_MCF10A.WT.HP_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70395
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.77474
Perturb_7595_KD_NSUN2_SRP384110	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.38224
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUTU80	Achilles Cell Line Gene Essentiality Profiles	1.0	1.55576
BRD-K87141723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05512
tretinoin-6243	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE145430_0_v_1_zmat3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1143
BRD-K81814927_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96222
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
NCIH1650	CCLE Cell Line Gene Expression Profiles	1.0	1.48203
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.8114
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TICRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06981
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867083
pravastatin-lactone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20397
BRD-K67941637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28854
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XXEK-0426-SM-4BRVW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955782
viomycin-7036	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.934294
ricinine-6206	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ESR1-22446102-UTERUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.878036
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protect	GeneRIF Biological Term Annotations	1.0	null
CRCGN011_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34675
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71834
5252917-944	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20J-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-491-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
chr5_128966192_T_G_b38	GTEx eQTL 2025	1.0	1.35406
LY-294002-6995	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SNMC-0426-SM-4DM5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973328
P53_DN.V2	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
KG1C	CCLE Cell Line Gene CNV Profiles	1.0	1.75073
H3K9me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE125153_1_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
fetus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089875
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10787250-BLOODA_ADV-2022-008899-mmc1.xlsx-Table_S7-Table_S7_Differentially_expressed_genes_commonly_up-_or_downregulated_in_CBFA2T3_GLIS2_leukemia_GLIS2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2475_KD_PHF8_SRP229951	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.70946
GTEX-PWOO-2426-SM-2S1OV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139540_0_v_2_menadione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
proton-transporting ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.055
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.994429
GTEx Nerve 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-10.4602
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.8036
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4795-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
BRD-K22443456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75646
Perturb_7732_KD_RRP6_SRP062389	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.88126
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17862
Fast muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.067
Very long chain acyl-CoA dehydrogenase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
Perturb_2960_Mut_H33A_SRP058766	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.443
UBAC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00538277
Lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.372
Perturb_2959_Mut_H33A_SRP058766	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
fallopiantube_8e	HPA Tissue Sample Gene Expression Profiles	1.0	1.25935
BRD-K76588804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14087
SOX3-22085726-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.373
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974018
Perturb_17427_KO_Shh_SRP141427	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.83067
molecular_function	GO Molecular Function Annotations 2015	1.0	null
BRD-K19327124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42645
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E6-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112860_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058451
FAM13A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0072601
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33256
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.862725
GSE122067_2_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A76490030_K784-3131_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4904
inner CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.899162
16818636-TableS3	GeneSigDB Published Gene Signatures	1.0	null
RUNX1T1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00518904
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	1.0	1.41192
CRCGN014_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02139
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K70237115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.46041
CRCGN017_MCF10A.WT.HP_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.23208
ESR1	ChEA Transcription Factor Targets	1.0	null
benzocaine-4808	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16176
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_15857_KD_KDM3A_SRP248023	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.73184
BRD-K59445060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15617
GSE222758_0_v_2_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K01638814_rilmenidine hemifumarate_H1299_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.19838
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
GSE222758_0_v_4_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Bone Density	DisGeNET Gene-Phenotype Associations	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K69536411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54979
KU-19-19	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47026
Perturb_2076_OE_PUM1_SRP072710	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.35728
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31393
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE232631_0_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain microvessel endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19967
Prostatic cyst	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPM-1826-SM-2YUNF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Adrenocortical carcinoma_ACC_TCGA-PK-A5H9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62971
BRD-K49328571_dasatinib_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_3583_KO_DNMT3A_SRP312248	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.0927
BRD-K26306512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0927
GTEX-WFG7-1626-SM-4LVMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Experimental Organism Basal Cell Carcinoma	DisGeNET Gene-Phenotype Associations	1.0	null
Uterine horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.768
Perturb_15108_KD_MPP8_SRP218207	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.1792
GSE131649_6_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-OHPK-1826-SM-2YUMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
5248896-955	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE221327_1_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216147_0_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FSCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04907
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17722
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71035
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059891
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06344
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K28874552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18932
Stearic acid	HMDB Metabolites of Enzymes	1.0	null
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.877511
BRD-K57343972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59261
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25733
GPKOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03336
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.915127
umbilical artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.193968
GSE150055_0_v_2_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K74391203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11581
SW837	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K17315445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89884
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8178
Lung adenocarcinoma_LUAD_TCGA-55-A4DF-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9656_KD_MEF2C_SRP306591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.4589
ECC12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81092
AMP-binding, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epididymis	HPA Tissue Protein Expression Profiles	-1.0	-0.748764
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4115
BRD-K12502280_TG101348_A375_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_15871_KO_PAX3/FOXO1_SRP293781	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.4112
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XOT4-0426-SM-4B66T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
U937	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94399
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WEY5-2126-SM-3GILK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
SLC39A8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00587413
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.830235
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K87889654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44929
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WZTO-1026-SM-3NM9P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.95947
Lung squamous cell carcinoma_LUSC_TCGA-77-6842-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-VN-1203-2004(H5N1)_Day1-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.73268
GSE102675_3_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119564_1_v_0_zfp217_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OHPL-1326-SM-3MJGG	GTEx Tissue Sample Gene Expression Profiles	1.0	3.12253
TNFRSF25	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00460435
PHA-00851261E-3965	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
heart	GTEx Tissue Gene Expression Profiles	1.0	0.949703
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.920712
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
16849537-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
tanespimycin-986	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WYVS-2426-SM-3NMA9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2408
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055326
SLC4A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00530004
BRD-K58382884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42026
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K24700188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20713
GSE210101,GSE210114_2_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.14015
LOX-1_OE_GDS4262_434_human_HAECT - aortic endothelial cell line - 12 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-QV31-0626-SM-447C5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
EZH2	ENCODE Transcription Factor Targets	1.0	null
EB2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05697
BRD-K29301364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.70732
hsa-miR-1236	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-WY7C-1126-SM-3NB3A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933014
NB1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58247
GTEX-QLQW-1426-SM-2S1QU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959561
BRD-K02130563_S1030_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K22002184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22723
chr5_129000131_G_A_b38	GTEx eQTL 2025	1.0	9.00855
ASAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18825
GTEX-QMRM-0926-SM-447BR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04382
GSE112860_0_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01858
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.23031
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7593-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998708
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01826
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040063
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SL-01B-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K29238078	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27806
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.585865
A-Netherlands-602-2009(H1N1)_48Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.84384
PMC7523182-Table_2.XLSX-Lipid_metabolism_pathways-RORA_RORA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ACN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850213
GSE221327_1_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.748764
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10394
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
1321N1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.09381
endoplasmic reticulum membrane	GO Cellular Component Annotations 2025	1.0	null
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
CCC5	DepMap CRISPR Gene Dependency	1.0	2.25315
CRCGN014_HEPG2_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.223
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8919
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1345
GTEX-PLZ4-1326-SM-2S1O7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.64375
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00896
tanespimycin-1005	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.349717
mRNA_SMAD7_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-VUSG-1026-SM-4KKZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867949
BRD-K28785305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62315
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28107
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.28861
GSE203429_0_v_1_angptl8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K21680192_mitoxantrone_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PDE3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00522286
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.841157
PMC9691391-7945884.f3.pdf-12-ENSG00000244405_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145323,GSE145324_1_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7854-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K54362440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83123
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
gestational diabetes	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.605762
GSE220520_3_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_4_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CLIC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00501469
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K85395981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29879
HT-1197	GDSC Cell Line Gene Expression Profiles	1.0	2.07887
REST_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K91039552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01283
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7898758-40168_2020_994_MOESM4_ESM.xls-PRDM15_target_genes-Gene_PRDM15	Rummagene Transcription Factor Associations 2026	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.190814
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K34700473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10764
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
GSE111102,GSE111105_1_v_5_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
platelet-type bleeding disorder 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.692
BRD-K73044744_KUC104495 KUC104495N_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-219-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Perturb_17802_KO_ZNF675_SRP305529	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.54349
GTEX-RNOR-0426-SM-2TF4U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2834
GTEX-WHWD-0426-SM-3LK83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83786
GSE227592_4_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K23589316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96521
BRD-K67860401_GSK-3b Inhibitor VIII_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9942993-pone.0281645.s002.xlsx-non-AR_as_all_as_gained-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE246195,GSE246305_2_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Perturb_6503_KD_PIEZO1_SRP140640	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.6594
Lipid droplet	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.062
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CNN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12615
BRD-K67665252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80136
BRD-K22383829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.72915
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63559
BRD-K50140147_NVP-TAE684_SKBR3_3_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-P4PP-2426-SM-3P61L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854806
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825836
CTBP2-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K45185240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29691
Perturb_317_KD_TP63_SRP353945	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.32613
FGFR3_KD_GSE41035_77_human_RT112	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
EFO-27	GDSC Cell Line Gene Expression Profiles	-1.0	-1.479
hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.152594
BRD-K52075040_-666_SKLU1_6.0_h_44.4_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.857474
phenylpropanolamine-5298	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE149075_8_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K70549064_EI-156_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
sirolimus-7001	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
import into cell	GO Biological Process Annotations 2025	1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20038
GTEX-X3Y1-0426-SM-3P5Z4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.223
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0394
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
establishment of localization	GO Biological Process Annotations 2015	1.0	null
BRD-K96170781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04638
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4192274__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K68617666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16455
GTEX-SNMC-0226-SM-4DM6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
15-delta prostaglandin J2-5591	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	2.30366
rolipram-5330	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	0.825615
VIM	Pathway Commons Protein-Protein Interactions	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K96239538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1558
Supportive connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.269
adrenal gland	GTEx Tissue Gene Expression Profiles	1.0	0.946539
Hypertrophy, Left Ventricular	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K92059157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06266
BACH1	ENCODE Transcription Factor Targets	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06649
umbilical cord blood cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.03697
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12889
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55607
BRD-K83794624_P8624_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.85717
GTEX-XV7Q-1226-SM-4BRVT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06951
GTEX-WFJO-0726-SM-4LVM8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09472
MORN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31686
Perturb_598_OE_HOTAIR_SRP342161	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.2272
CHD3	Pathway Commons Protein-Protein Interactions	1.0	null
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11701
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
BL-70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-A31916785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16896
Perturb_4859_KD_BCOR_SRP119523	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.47633
AM-38	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	147.54
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062219
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
DENND4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04863
GSE236262_2_v_1_trim28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SW1990	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66456
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.3665
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2096_KD_TENT4A_SRP237261	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.34788
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.837601
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01848
Perturb_13136_KO_Gadd45a/Ing1_SRP149486	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.746
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K53168433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86889
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K87909389_HY-10005_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.833839
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.29462
LIVF001-025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05248
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.981765
Perturb_3221_OE_Csf1_SRP265786	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.83632
BRD-K10820981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1488
Metabolic dysfunction-associated steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
erythromycin-5329	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VPS29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47523
GSE131649_6_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.860319
OVMANA	DepMap CRISPR Gene Dependency	1.0	6.02367
Perturb_7234_KD_UPF1LL_SRP295982	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.67145
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18436
GTEX-XUJ4-2726-SM-4BOQ1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867858
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824262
BRD-K58846294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42608
GTEX-RTLS-0326-SM-2TF6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920109
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.82967
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.29882
Perturb_6504_KD_PIEZO1_SRP140640	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.29817
SH2B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35643
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.98341
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.96391
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17217
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31989
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7216
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Perturb_4848_KD_NKX25_SRP059197	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.2309
GSE213588_9_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4362
PAK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02422
GSE58724_1_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Placenta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.823
ELF1	ENCODE Transcription Factor Targets	1.0	null
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K66214118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06448
GSE221327_4_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_6_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
CAMKK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05324
PRPS1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39904
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.57965
PROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28964
N6-methyladenosine-5332	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K61182411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60946
Prostate adenocarcinoma_PRAD_TCGA-HC-A76X-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.139
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24833
CD70	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605929
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
ADH1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00693083
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824262
Perturb_13019_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.39336
BRD-K32636001_MLS-0437446.0001_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K48755012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2847
CRX-20693478-ADULT_RETINA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
dipyridamole-5252	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.910048
NCIH292	DepMap CRISPR Gene Dependency	1.0	2.52503
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-1826-SM-4E3JV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17211
GTEX-R53T-0926-SM-3GADH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68862
GSE113267_0_v_1_rfx7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
heart	GeneRIF Biological Term Annotations	1.0	null
GSE217405_0_v_1_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WHWD-0326-SM-3LK6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09426
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIP1R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00434096
NUDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09418
flavoxate-7405	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ISHIKAWAHERAKLIO02ER	CCLE Cell Line Gene Expression Profiles	1.0	1.62546
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_SUZ12-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826143
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
trichostatin A-6276	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Perturb_9631_KD_CHD8_SRP047233	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.79544
GTEX-UJHI-0226-SM-4IHJL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Perturb_1612_KO_Sidt1/Sidt2_SRP335374	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.34798
orbital frontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37153
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24254
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1146
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00575
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02643
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.883389
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71377
GTEX-OHPM-0726-SM-3LK7A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70985
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45845
TYK-NU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36055854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09706
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GTEX-S32W-2226-SM-2XCAY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1422
Perturb_14285_OE_YAPS127A_SRP336792	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.38666
GSE171572_0_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100626_FWM_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66328
BRD-K81418486_vorinostat_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_3007_KD_Satb1_SRP068358	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.75433
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.12646
S100A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44161
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.386208
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07735
CRCGN010_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.15722
ZNHIT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2455
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881618
CRCGN010_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7901
BRD-A76490030_K784-3131_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.71672
BRD-K12867552_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRAK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00559963
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.990042
GTEX-S32W-1226-SM-4AD67	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10787
BRD-K60295429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14754
yohimbine-1119	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231648_4_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hek-293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.31332
chlorpromazine-5577	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
G2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18387
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.40024
SNU1077	CCLE Cell Line Gene CNV Profiles	1.0	1.99251
CRCGN015_MCF10A.TP53.M_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.5529
PMC9362915-pone.0272017.s003.xlsx-Day5_-0_7_Top-BBX_BBX	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Transport of fatty acids	Reactome Pathways 2024	1.0	null
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844594
PMC10315050-12920_2023_1588_MOESM2_ESM.pdf-27-THAP9_THAP9	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81H-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.83833
GTEX-QESD-1726-SM-2S1R7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43684
E2F4	ENCODE Transcription Factor Targets	1.0	null
BRD-K13999467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10027
HPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.49934
cisapride-5305	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	125.343
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05217
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824262
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
Spongiotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
SOX2-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DMS153	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45646
GTEX-UJHI-1626-SM-3DB9A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
CRCGN016_MCF10A.WT.HP_24H:E21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1813
ELK1-22589737-MCF10A-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PB-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
RH-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.11977
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.998708
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
emetine-2801	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12148_OE_CENPA_ERP125655	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.54474
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0326-SM-32PL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21826
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903118
BRD-K16826019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01105
WM35	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H2BC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08458
GTEX-RWSA-0526-SM-2XCBC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.2693
corbadrine-7208	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61168987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04772
Perturb_13912_KD_TARDBP_SRP169127	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.74508
Subcortical volume (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.7
GTEX-U3ZN-0426-SM-4DXSH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K52914903_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ceforanide-5351	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
fatty acid transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
CRCGN015_MCF10A_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3835
sirolimus-1001	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.836175
BRD-K18294143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	1.0	2.05641
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.893
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03772
GTEX-XV7Q-1426-SM-4BRWA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64625
BRD-A10417568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17635
GSE235682_1_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
localization	GO Biological Process Annotations 2015	1.0	null
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46273
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47713
Intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	1.0	3.81156
TNFRSF10C	Pathway Commons Protein-Protein Interactions	1.0	null
EFO-21	GDSC Cell Line Gene Expression Profiles	-1.0	-2.05455
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	1.19684
kidney_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.09213
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38104
Perturb_6308_KD_PUM1_SRP396076	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.0259
CRCGN017_MCF10A.WT.HP_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0119
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A83N-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
PMC6870463-Table_7.xlsx-Family_H_No_LPS-Untreated_BMDMs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13646352_PKC-412_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IL4I1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0053674
orbital frontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.93233
dexibuprofen-5311	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CUTC	Pathway Commons Protein-Protein Interactions	1.0	null
Persistent Atrial Fibrillation	DisGeNET Gene-Phenotype Associations	1.0	null
SKMM2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.6979
BRD-K29143088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05364
Placental disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.934
GTEx SalivaryGland 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	4.32644
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0709
HPAFII	CCLE Cell Line Gene Expression Profiles	-1.0	-2.09742
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55329
GSE210101,GSE210114_0_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10818
BRD-K94493764_NP-009169_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
U178	Achilles Cell Line Gene Essentiality Profiles	1.0	1.05706
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201309_1_v_2_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_10_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SK-N-FI	GDSC Cell Line Gene Expression Profiles	1.0	1.68475
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44937
GSE190316,GSE190324_1_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16653
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147662_3_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7953-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K84802956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1377
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069465
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	123.023
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K23841751_HTS 10859_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24594
Uterine fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.055
BRD-K45712538	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44222
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SSA3-0526-SM-32QPL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903275
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K17232330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40083
TRIP10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00459759
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8946
GSE216043_11_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OHPK-1726-SM-48TC4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828013
pre-eclampsia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
STC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00573119
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20037
BRD-A39093044_K784-3187_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.23429
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6026
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.776
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3273_KO_Aim2_SRP201902	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.13374
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K10398797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00345
BRD-K13938991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85747
GSE190316,GSE190324_6_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE218879_1_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10667
PYCR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00857139
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00241
lcfa	GeneRIF Biological Term Annotations	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Fumarate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.646
GSE217405_3_v_2_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QDVJ-1126-SM-48U1U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869215
GTEX-SN8G-0526-SM-32PLE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110268_1_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE232631_4_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K80690345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04535
GSE196699_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100590_FWM_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.61654
GTEX-R55E-0426-SM-2TC65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26555
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71377
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_JK_LPS-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5498-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APLNR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02085
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE264010_0_v_1_parp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K01896723_2-morpholino-N-((5-nitro-1H-benzo[d]imidazol-2-yl)methyl)-9-(thiophen-3-yl)-9H-purin-6-amine_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-A75931230_7706-0139_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157555,GSE157556_5_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM62	Pathway Commons Protein-Protein Interactions	1.0	null
GSE168076,GSE168080_1_v_0_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tiratricol-2259	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35504
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.72045
BRD-K37308886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01877
SNU1272	CCLE Cell Line Gene CNV Profiles	1.0	1.51232
COLO680N	CCLE Cell Line Gene CNV Profiles	-1.0	-2.30741
BRD-K94441949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.65163
ELK1	ChEA Transcription Factor Targets	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
VIM	Hub Proteins Protein-Protein Interactions	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D4_vs_D9-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UJMC-0526-SM-3GAE3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04165
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.707113
cellular process	GO Biological Process Annotations 2015	1.0	null
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30414
GSE148262,GSE150691_1_v_0_hdlbp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K31233830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04255
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Rennet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.703
TCF12	ENCODE Transcription Factor Targets	1.0	null
BRD-K74148702_curcumin_H1299_6.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13506
BRD-K83270266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09018
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K77541177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14543
BCP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64122
BRD-K62289640_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE123943_4_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K62692910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02727
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86778
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_H3K27me3-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.962162
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5250-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Perturb_2493_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NFK9-0426-SM-2YUNK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57082
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWN1-0726-SM-48TDR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946338
BRD-K22800340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26729
Cardiovascular Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
SNU16	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89084
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826771
Neoplasms	CTD Gene-Disease Associations	1.0	1.24687
GTEX-PLZ6-0626-SM-3P61B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05733
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.978724
trimipramine-3342	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IL15RA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00522922
BRD-K31758107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42113
withaferin A-4376	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Placenta disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.074051
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RU72-1226-SM-2TF6N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
FCN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00752555
primary motor cortex (area M1, area 4)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.60399
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Preadipocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.267
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-S7SF-2126-SM-3K2B2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57029
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-Overlap-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ELK1-22589737-MCF10A-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7314-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	0.97887
BRD-K94247332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02929
BRD-K94115999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23146
KMOE-2	GDSC Cell Line Gene Expression Profiles	1.0	1.45343
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_6260_KD_NDP_SRP188348	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.7635
BRD-K49103797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14263
mediodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05443
Perturb_7710_KO_VTRNA1_SRP252980	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.56614
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ACC3	BioGPS Cell Line Gene Expression Profiles	1.0	0.926417
very-low-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.679
CRCGN017_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5309
GTEX-U8XE-1226-SM-4E3HN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19697
Respiratory Function Tests	dbGAP Gene-Trait Associations	1.0	0.51105
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.385
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40316
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42507
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7644-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endometrial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
PMC4283159-ajas-28-2-158-supplementary.pdf-24-MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13795
long-chain fatty acid transport	GO Biological Process Annotations 2023	1.0	null
Perturb_404_KO_LIN54_SRP272209	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.37879
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.32555
CRCGN008_HEPG2_24H:E21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.164
Lung adenocarcinoma_LUAD_TCGA-62-A46O-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Coffin-Siris syndrome 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
GTEX-TMMY-1226-SM-4DXT6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59405
hsa-miR-4477a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
JHH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K14163107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.41361
BRD-K39543844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09931
Perturb_13955_OE_MAML3_SRP320511	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.35596
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1623	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K15025317_Bay 11-7821_RKO_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNU349	CCLE Cell Line Gene CNV Profiles	1.0	2.80448
long-chain fatty acid metabolic process	GO Biological Process Annotations 2015	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910526
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.2136
BRD-K92246187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00689
lipidrelated	GeneRIF Biological Term Annotations	1.0	null
HDLM2	CCLE Cell Line Gene CNV Profiles	1.0	1.64899
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.47713
GSE110440_2_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.183
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
PMC9894241-pnas.2211429119.sd05.xlsx-G7_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17058
IFI35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4339
CRCGN017_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2941
BRD-K45569026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65863
Sebocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46685
GTEX-PWN1-1826-SM-2S1PE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Sarcoma_SARC_TCGA-DX-A7EI-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1309
Ebolavirus(ZEBOV)_1day_Spleen_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.02412
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.84715
heptaminol-1703	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K29903249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11646
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30462
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.29201
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85162396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80285
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.767
BRD-K26809097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55914
BRD-K04155570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13127
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.317182
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.28611
GTEX-R55G-0126-SM-48FDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17008
Perturb_13952_OE_lncNR2F1_SRP179994	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.38658
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJMC-0426-SM-4IHJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Congenital right-sided heart lesions	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PTGER3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00554991
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	1.19684
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.76151
BRD-K77578964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6312
BRD-K16554464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4082
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K09594570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06527
CRCGN017_MCF10A.WT.HP_24H:D14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13995
PMC6757314__F3	PFOCR Pathway Figure Associations 2024	1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100656_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2929
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04371
nordihydroguaiaretic acid-1003	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
BRD-K39464795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14877
GTEX-OIZI-1126-SM-3NB1F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04487
BRD-K81110981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13719
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4519
EGR1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-h-Classification_of_camel_SON_basal_genes_-_transporters_SON	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K72895815_SSR 69071_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K20428189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73321
GTEX-XV7Q-1026-SM-4BRVR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893005
very long-chain fatty acid metabolic process	GO Biological Process Annotations 2023	1.0	null
PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K16485616_S1122_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_3693_KO_GPX8_SRP353993	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.99653
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149903_4_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	133.27
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00473
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RH18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71271
ionomycin-882	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SP110	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00566046
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cortical surface area (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.9
RUNX1	ChEA Transcription Factor Targets	1.0	null
PMC7468443-Data_Sheet_5.xlsx-LPS_2h_over_6h-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HCT116	BioGPS Cell Line Gene Expression Profiles	1.0	1.25159
BRD-K84278600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.02004
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6031
496100483_FWM_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.4014
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A375	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-3B-A9HQ-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ferulic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8449
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72546
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
digoxin-5324	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
monorden-836	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K12873970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21279
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X5EB-0626-SM-46MVQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9737
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.22979
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cefotaxime-7186	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC10120965-pwac038_suppl_supplementary_table_s4.xlsx-siFOXP1-2_vs_siNC-Differentially_Expressed_Genes_DEGs_in_hCMs_upon_Silence_of_FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2726
LY-294002-5596	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.695
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52123140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56911
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.03852
GSE205630_0_v_1_gmds_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH508	CCLE Cell Line Gene Expression Profiles	-1.0	-2.56095
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VSIG8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0053294
monocarboxylic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01269
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Myristic acid	HMDB Metabolites of Enzymes	1.0	null
very long-chain fatty acid metabolic process	GO Biological Process Annotations 2025	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
BHLHA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13637
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072397
Perturb_9628_KD_CHD8_SRP047233	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.39457
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.19684
BRD-K01980291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11858
DUSP16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0054085
GSE118430_0_v_1_xbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216988,GSE216989_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3118	DepMap CRISPR Gene Dependency	1.0	2.93209
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
liver	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
natamycin-3548	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08327
CRCGN016_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00068
ligase activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K24377650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12396
BRD-K40649636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38669
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52625
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18725
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0141
GTEX-WH7G-2626-SM-3NMBE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0248
GSE221327_8_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_16497_KO_MESP2_SRP153048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.1622
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35812
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
benserazide-641	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K62497619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01217
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8635-11A-01R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128634,GSE128636_4_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K28296557_Akt inhibitor IV_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_18447_KD_H2AZ2_SRP199104	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.37981
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8071
BRD-K74927219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04015
Perturb_9697_KO_CHD8_SRP061880	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.33828
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17058
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K01281780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03029
GSE205729,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824262
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PW2O-1926-SM-2S1OB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
CRCGN011_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64845
ZBTB17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01875
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
fenofibrate-7474	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE128688_0_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
P2URK562	DepMap CRISPR Gene Dependency	1.0	6.91532
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MESP1_cust_MESP1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-A19500257_geldanamycin_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7602-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9406_KD_GATA6AS_SRP279802	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.14051
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050662
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942065
nilutamide-5362	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hippocampus (hippocampal formation)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37017
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06747
GSE214442_0_v_1_pak4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01626
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-01A-12R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney	HPA Tissue Gene Expression Profiles	-1.0	-1.306
H3K27me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
U251MG	CCLE Cell Line Gene Expression Profiles	1.0	1.39418
GTEX-V955-0126-SM-4JBH5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891628
GSE131425_2_v_3_arg2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.558
nerve	GTEx Tissue Gene Expression Profiles	1.0	0.9775
GSE148692,GSE148695_1_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9952
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_DOWNREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.18652
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878979
BRD-K07525144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86516
ANKRD27	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00451687
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K27616520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K64632606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06754
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.61202
GTEX-WEY5-1126-SM-4LMIE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918125
5252917-828	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SLC-mediated transmembrane transport	Reactome Pathways 2024	1.0	null
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.876545
BRD-A62025033_temsirolimus [CI779]_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN010_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.94376
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16577
kidney	GTEx Tissue Gene Expression Profiles	-1.0	-1.00672
GTEX-O5YT-0226-SM-32PK5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE239747_2_v_3_lrp6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7	CCLE Cell Line Gene Expression Profiles	1.0	1.71785
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE168807_0_v_8_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01197
BRD-K93677460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12092
BRD-K13719101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6959
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.846786
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-0326-SM-4DM6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
chr5_128917534_C_T_b38	GTEx eQTL 2025	1.0	4.39813
Teratogenesis	CTD Gene-Disease Associations	1.0	1.08513
PPAR signaling pathway(Mus musculus)	WikiPathways Pathways 2014	1.0	null
ETS1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Congenital contractural arachnodactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.136
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
stat3_00000000_a549_lof_human_gpl571_gse42979	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.02749
PMC4241130__F2	PFOCR Pathway Figure Associations 2024	1.0	null
PMC5675652__F6	PFOCR Pathway Figure Associations 2024	1.0	null
Myoclonic cerebellar dyssynergia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
serotonin-5268	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
M059K	CCLE Cell Line Gene CNV Profiles	1.0	1.37432
Hs-578T cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.916
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.930715
HCC1897	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32369
Perturb_15812_Mut_RP2_SRP255721	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.45333
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31699
GTEX-U3ZM-0826-SM-4DXU6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K29628583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12733
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12670081-mct-24-0704_supplementary_table_s10_suppst10.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Differential_expression_of_TFCP2-rearranged_RMS_Vs_Other_RMS_FC_3_padj_0_01_TFCP2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03357
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20707
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
estradiol_homo sapiens_gpl96_gse4668	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7479-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Paroxysmal Atrial Fibrillation	DisGeNET Gene-Disease Associations	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K32699895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46829
naphazoline-1466	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE240258_0_v_1_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRK-0826-SM-2HMK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21751
BRD-K01896723_2-morpholino-N-((5-nitro-1H-benzo[d]imidazol-2-yl)methyl)-9-(thiophen-3-yl)-9H-purin-6-amine_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.413532
COV644	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66894
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X3Y1-2426-SM-3P5Z7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89929
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_2384_KO_ASXL1_SRP333775	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.73956
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K90655269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10666
Sarcoma_SARC_TCGA-K1-A42W-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1726_KO_Zeb1_SRP269619	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.7612
EZH2_DEPLETION_GDS2445_117_human_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE165579_0_v_1_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03051
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16553
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
17703498-Table2	GeneSigDB Published Gene Signatures	1.0	null
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.838728
HUG1N	CCLE Cell Line Gene CNV Profiles	-1.0	-2.17792
chr5_128949968_C_T_b38	GTEx eQTL 2025	1.0	1.1248
TSPAN7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00589402
H3C7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31634
P63-26484246-CHIP-SEQ-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC3923219-mmc2.xls-Table_S1-Table_S1_Differential_Gene_Expression_in_GFP-PRDM1_transduced_H9_hESCs_PRDM1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Microbody membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.134
rottlerin-941	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42261
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-0626-SM-4IHK2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25134
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.64895
BRD-K91506006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62032
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206516,GSE206518_2_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trichostatin A-6993	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K76680796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05926
HRH2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00584823
Fatty acid elongase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.207
GTEX-U4B1-0126-SM-4DXSN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07964
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_8717_KO_DHRS4AS1_SRP370273	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.23919
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29025
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27619
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00365
GSE100316_7_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JHOS2	CCLE Cell Line Gene CNV Profiles	1.0	2.38242
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09961
GTEX-WRHU-0626-SM-3MJFI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935294
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SJSA1	CCLE Cell Line Gene CNV Profiles	1.0	1.48205
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K27me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5783-01A-41R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCCSTCK140	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42826
hsa-miR-4782-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE130396_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
creb1_18801183_k562_lof_human_gpl570_gds3487	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-2.23873
BRD-K58642524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35239
CAPAN1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98803
BRD-K91282650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25292
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62971
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.395
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
496100592_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15984
POLRMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27247
GTEX-XBEW-1426-SM-4AT4J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955805
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Slow muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.969
Perturb_13534_KO_HDGFL2_SRP153901	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.51412
GTEX-WEY5-0726-SM-4LMID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K88278225_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A34826857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5816
CRCGN009_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.36379
BRD-K52175660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54214
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6137307-mmc2.xlsx-STAT2-IFNa-Table_S1_STAT2-IFNa_Related_to_Figures_1_4_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.402
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92398088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83463
GSE231891_5_v_4_cdk8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ8I-1426-SM-4BOPW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.937775
CRCGN017_MCF10A.WT.HP_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5313
GSE210101,GSE210114_2_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
hecogenin-7175	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_9450_OE_SOX9_SRP297132	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.13243
primary somatosensory cortex (area S1, areas 3,1,2)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01612
Leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.396
LOUCY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65778
BRD-K86923998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80816
CACNG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27378
kidney_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.18066
raloxifene-3480	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TRAF3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00490679
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
MZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.992205
alpha-estradiol-990	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE139911_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.96028
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
BRD-K11636097_S1249_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K14853757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39953
Weight Gain	CTD Gene-Disease Associations	1.0	1.05936
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_02_183	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.67423
GTEX-U8XE-0526-SM-3DB8R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918345
PMC9549388-mmc6.xlsx-PPAR-PPARA_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_9137_KD_HMGB2_SRP106038	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE132948,GSE132949_0_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_7_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K35520972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93038
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37691127_Hinokitiol_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K12589632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40057
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
15897907-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XPT6-2126-SM-4B66P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02292
mammary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.345558
BRD-K81586131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14665
18757322-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8336-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K38282015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.154
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870813
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50161
BRD-K48478472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18743
Carapace	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.54
STAT1-17558387-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	0.883895
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Fatty acid synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.547
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.879242
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96202
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	1.14539
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5954
indometacin-5468	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Umbilical artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
PMC10679662-mmc2.xlsx-NC-D5-ZEB2-siRNA-Upregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K72238567_656402-250MG_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1976
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K70286959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51137
GTEX-TKQ2-1226-SM-4DXSV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57826
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41B-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MANBAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21982
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.42191
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.19684
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Atrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.043
GTEX-WEY5-1026-SM-4LMK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27617
BDCM	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54319
BRD-K07502463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0149
estradiol_homo sapiens_gpl570_gse23610	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE227592_8_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K91426044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23395
BRD-K50004365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14809
BRD-K91349888_arg-a1-22 BRD-K91349888_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6703
BRD-A68175400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56916
MEIS1-26253404-OPTIC-CUPS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE175787_8_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825836
phenanthridinone-1115	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
diclofenamide-5286	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fluvoxamine-4114	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE188884,GSE189078_2_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.49137
GTEX-TML8-1626-SM-32QOO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08302
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063579
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K81418486_vorinostat_A375_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TP53I3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00495471
HOXA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00600437
RPS3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46345
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K63547380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26727
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.906
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1307
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30663
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JAK2_mutant_40_GSE11003	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.6922
BRD-K61087440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.575
BRD-K01877528_TL_HRAS26_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	1.0	1.16033
metergoline-5344	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K88437756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16512
BRD-K94439911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27995
BRD-K40019775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00273
meclofenoxate-4729	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RWS6-1026-SM-47JXD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934418
GTEX-S33H-0726-SM-4AD6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-PWCY-2226-SM-2S1OP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K35681049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36576
PMC3255547-supp_007401_DMM007401TableS6.xls-EWS-FLI1_signatures-Unnamed_3_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12709797-12879_2025_11916_MOESM1_ESM.pdf-21-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
Synaptic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.323
GSE116299_0_v_5_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.32256
Perturb_10698_KD_CD274_SRP307356	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.28329
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7252-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210101,GSE210114_0_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
Organelle subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
cellular_component	GO Cellular Component Annotations 2015	1.0	null
PUF60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21502
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.62297
GTEX-S4Z8-0426-SM-3K2AH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
SP in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.67394
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.55874
SR-95531-4820	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02979
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.17629
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.63226
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
fluticasone-4129	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-WZTO-1126-SM-3NM93	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GCT	CCLE Cell Line Gene CNV Profiles	1.0	1.84424
BRD-A86550573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46605
Brush border	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.184
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_17622_KO_NF2_SRP153109	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.74852
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Sarcolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.604
RUNX2	ChEA Transcription Factor Targets	1.0	null
metabolic	GeneRIF Biological Term Annotations	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE215351,GSE215794_2_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.22274
LNZ308	CCLE Cell Line Gene Expression Profiles	1.0	1.51593
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11960529-mmc4.xlsx-Ventricular_ZNF711_KOoverCT-gene_ZNF711	Rummagene Transcription Factor Associations 2026	1.0	null
GSE173873_1_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10561
CRCGN010_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1874
FAM199X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03941
BRD-K04992384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01401
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Mesothelioma_MESO_TCGA-MQ-A4LP-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.877671
GTEX-W5WG-2226-SM-4LMI3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
dinoprostone-6590	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.840914
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	139.23
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19967
PMC12178937-mmc6.xlsx-D_MAFF_KDvsD_C_deg_all-gene_id_MAFF	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:J15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8672
Perturb_15967_KO_Tbet_SRP063567	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.14504
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCH	GDSC Cell Line Gene Expression Profiles	1.0	1.54519
heart_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.08488
Perturb_3694_KO_ANGPTL8_SRP376269	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
small intestine	HPA Tissue Protein Expression Profiles	-1.0	-0.748764
Perturb_12720_KD_KMT2C_SRP110043	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Sarcoma_SARC_TCGA-DX-A3UC-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EDA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00663748
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00838
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.05936
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73996
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.395
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Longissimus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.649
GSE153663,GSE153664_1_v_0_zeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS766T	CCLE Cell Line Gene CNV Profiles	1.0	2.6548
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.07589
EIF3I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28445
hsa-miR-4282	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.541377
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76821
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
GTEX-TKQ1-0426-SM-4DXT4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906663
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU8-0226-SM-2XCDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7008
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868422
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0452
ventrolateral prefrontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3005
BRD-K29338816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02489
SW900	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.405
BMI-1_DEPLETION_GDS2445_115_human_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.07128
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K56336567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87951
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K24133768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26715
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51061
CRCGN009_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47296
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.02851
BRD-K68036990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19692
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.979448
quinostatin-973	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_14847_KD_PEG10_SRP055517	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.6856
Perturb_7555_KD_SP1_SRP303813	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.2663
ovary	HPA Tissue Protein Expression Profiles	-1.0	-0.748764
COPB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20196
fatty acid transport	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5303-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K15523383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53371
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5083-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chorionic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.018
intermediate-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.625
BRD-K86978618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59643
Lung adenocarcinoma_LUAD_TCGA-50-5935-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TKQ1-1326-SM-4DXU7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1254
PMC8202205-NIHMS1706275-supplement-Table_S3.xlsx-Day_4_GATA6-dependent_genes-GATA6-dependent_mRNA_expression_Day_4_Definitive_Endoderm_FDR_0_05_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
SB-203580-6915	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29978
Kidney Chromophobe_KICH_TCGA-KL-8328-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pulmonary hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
BRD-K78656517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05396
CRCGN015_MCF10A.WT.HP_24H:I09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.09554
biological_process	GO Biological Process Annotations 2015	1.0	null
AMO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40124
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cvd	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-548k	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
puromycin-3310	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PI16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00581901
GTEX-R55D-1226-SM-48FE9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51527
GSE239747_1_v_3_lrp6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K03821002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01825
BRD-K28640166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.023
BRD-K21695872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38065
SNU620	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
BRD-K21283037_Riluzole hydrochloride_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K37304120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52018
GSE210101,GSE210114_5_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Lung adenocarcinoma_LUAD_TCGA-50-6595-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dienestrol-6208	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.83735
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUZC-0526-SM-4BOPF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890745
Perturb_8061_KO_ZCCHC4_SRP350212	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.82218
hippocampus (hippocampal formation)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.853155
BRD-K78015078	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33065
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16892
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42261
GTEX-WFON-2226-SM-3TW8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
SIRT6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00618281
GSE239844_11_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-0726-SM-3GIK1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02319
PMC12178937-mmc6.xlsx-D_MAFF_KDvsD_C_deg_all-gene_name_MAFF	Rummagene Transcription Factor Associations 2026	1.0	null
HS255T	CCLE Cell Line Gene Expression Profiles	1.0	2.26151
BRD-K27782186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24289
BRD-K11927976_ER 27319 maleate_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nicergoline-6251	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OIZH-1326-SM-3NB1H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18393
Arachidic acid	HMDB Metabolites of Enzymes	1.0	null
GTEX-NPJ8-1826-SM-2YUNC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Age related macular degeneration 10	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PM-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12443547-DataSheet5.pdf-3-WT1_1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.90945
GTEX-XBED-1126-SM-48TCF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837773
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
NCIH28	CCLE Cell Line Gene CNV Profiles	1.0	1.45097
GTEX-XUZC-0126-SM-4BOO6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE112860_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K75128590_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8424-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15025317_Bay 11-7821_U937_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.288668
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09984
BRD-K89632963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25894
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
primary motor cortex (area M1, area 4)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08309
GTEX-X3Y1-0226-SM-3P5Z5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961724
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
CRCGN015_HEPG2_48H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20505
CRCGN013_HEPG2_24H:N13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.67479
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3745
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.78011
Familial Atrial Fibrillation	DisGeNET Gene-Phenotype Associations	1.0	null
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC1005	Achilles Cell Line Gene Essentiality Profiles	1.0	1.96402
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9208
ECC10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44529
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.05762
Left Ventricular Hypertrophy	DisGeNET Gene-Disease Associations	1.0	null
Dicarboxylic aminoaciduria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
GTEX-REY6-0326-SM-2TF5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26552
Cytoplasmic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.562
BRD-K17854062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20745
KLE	CCLE Cell Line Gene Expression Profiles	1.0	1.6334
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33513
CHLA57	DepMap CRISPR Gene Dependency	1.0	2.28466
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
t61-colon_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.69197
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SOX9-26525672-CHIP-SEQ-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCIH1694	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87185
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67044
BRD-K09900382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2654
BRD-K74933734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19581
ventrolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.63343
hsa-miR-186	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE190316,GSE190324_10_v_11_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K68202742_trichostatin A_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K16682693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24655
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QCQG-2026-SM-2S1PH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06156
BRD-K73789395_ZM 336372_VCAP_6.0_h_102.71_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67891
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
meta7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.19
SUIT-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.584
Basal part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.55
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0018
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8891_OE_ANT2_SRP381834	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.75735
lorglumide-6456	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1596
furan	CTD Gene-Chemical Interactions	1.0	null
Heptadecanoic acid	HMDB Metabolites of Enzymes	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46876
Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216147_2_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K64606589_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K68450812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29706
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12068_OE_circDOCK1_ERP131190	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.30766
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	140.201
BRD-K15563106_-666_A375_24.0_h_177.6_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
medial nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.952373
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-NFK9-1326-SM-3LK5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.002
GSE174586_0_v_1_slc4a11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_14146_KO|KD_KBTBD4|RCOR1_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.88379
RCAF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.571
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.908078
COLO678	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48959
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K96799727_Pifithrin- ?_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K08142337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30341
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-P4QS-1826-SM-2S1NI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K26838195_AST1306_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Subcutaneous adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.559
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K87909389_HY-10005_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Mitochondrial proton-transporting ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.823
BRD-K64800655_HY-11001_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.64655
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67601
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
clotrimazole-6207	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
colecalciferol-5002	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE217405_3_v_2_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XUW1-1126-SM-4BONZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K47349869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41089
PMC4742856-srep20328-s7.xls-Sheet2-ZF_converted_to_Human_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
cardiac	GeneRIF Biological Term Annotations	1.0	null
triglyceride-rich plasma lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.671
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE136894_1_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4Q7-1326-SM-4AD74	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.83388
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lat1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.491
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873929
Perturb_18451_KD_H2AFJ_ERP124778	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_2483_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC27A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00425018
Perturb_1991_KD_ALKBH1_SRP323764	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.3553
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.112
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42639
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	2.02662
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7981
GTEX-VUSG-2726-SM-4KKZJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08142
Aflatoxin B1	CTD Gene-Chemical Interactions	1.0	null
primary auditory cortex (core)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08022
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63559
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.920862
GTEX-RM2N-0126-SM-48FDD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854254
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
phentolamine-1138	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TT	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.443
Bgm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.503
GSE131649_2_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE248045,GSE248046_0_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
clozapine-6947	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.04721
BRD-A73741725_EXEMESTANE_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K12502280_TG101348_SKMEL28_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K71247208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39136
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44282
GTEX-N7MS-0225-SM-4E3HO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09321
thioridazine-6989	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
Perturb_15109_KD_MPP8_SRP218207	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.377
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.395
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81A-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K00974016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35114
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67638302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54851
Persistent fetal circulation syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.673
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4721
GSE210101,GSE210114_6_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195559_8_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE186287_1_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
mammary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.406694
SLC-mediated transmembrane transport	Reactome Pathways 2014	1.0	null
BRD-K49409947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18125
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42L-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
appendix	HPA Tissue Protein Expression Profiles	-1.0	-0.748764
GSE221327_1_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05697
Congestive Heart Failure	DisGeNET Gene-Disease Associations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02364
GTEX-WFJO-0426-SM-4LVM7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90467
GSE113817_0_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4042
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92001
GTEX-S341-0426-SM-4AD5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38223
BRD-K11589884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85854
BRD-K45471346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15766
BRD-K79904333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90362
Perturb_8656_OE_ESRRG_SRP304240	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K84199148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46789
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1265
OCIM1	CCLE Cell Line Gene Expression Profiles	1.0	1.37462
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H-EMC-SS	GDSC Cell Line Gene Expression Profiles	1.0	1.76363
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
G6PC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00526284
Perturb_11707_KD_NUDT21_SRP127253	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.80461
Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LNCAP	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.987474
GTEX-QDVJ-0826-SM-48U1S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4623
alvespimycin-993	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
spironolactone-6255	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K47776393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0346
CRCGN014_HEPG2_3H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25765
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5218
KANSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24348
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01323
SC-560-6913	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28378
BRD-A47598013_citalopram_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53504
DJ-1_KD_GDS3750_373_human_SH-SY5Y	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Glycinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.863
GSE242049_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08068
hsa-miR-3675-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.255594
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825836
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
18667080-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Perturb_12573_Mut_MAGEA11_SRP255971	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.69072
Mammary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.533
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.685197
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LA-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXJ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49743
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5627
ramipril-6792	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
haloperidol-1041	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.832331
BRD-K29331543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25393
fatty acid metabolic process	GO Biological Process Annotations 2025	1.0	null
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
HCC2814	Achilles Cell Line Gene Essentiality Profiles	1.0	1.21671
GTEX-WHWD-2326-SM-3LK6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868946
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825836
chr5_128991908_C_G_b38	GTEx eQTL 2025	1.0	1.30663
GSE86507,GSE86509_4_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09327
Squamous cell carcinoma of mouth_Oropharynx Epithelium_GSE3524	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.49194
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8554124-DataSheet2.XLSX-34-RFX3_RFX3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SNOS-0726-SM-4DM5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28503
PMC5675652__F6	PFOCR Pathway Figure Associations 2023	1.0	null
sarcolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.776841
TRIFLUPERIDOL-2HCL	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.52648
Microbody	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.022
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.14365
GSE210101,GSE210114_7_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74589
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K56729241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59326
PMC5889507-NIHMS948947-supplement-Table_S7.xlsx-Hoja1-Table_S7_RAP1_Genomic_Binding_Peaks_in_Genes_within_the_PPAR_Signaling_Pathway_Related_to_Figure_7_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
papaverine-2747	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN012_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.27393
GSE221327_4_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.64468
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_13603_KD_KLF4_SRP221596	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.96959
SOWAHC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00533774
Perturb_11448_KD_PON2_SRP398037	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.19651
GSE147662_2_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
valproic acid-5574	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
phenoxybenzamine-5248	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940066
GSE207282_1_v_0_polydatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
REH	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.09165
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15236
GTEX-XUJ4-0926-SM-4BOPA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23533
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.84796
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE216147_0_v_3_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
(-)-atenolol-5325	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12306
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ligase activity, forming carbon-sulfur bonds	GO Molecular Function Annotations 2015	1.0	null
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KNS60	DepMap CRISPR Gene Dependency	1.0	3.21865
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05819
Perturb_14815_KD_Eral1_SRP293259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.52689
BRD-K30682979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02144
GSE216273,GSE216292_14_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Uninucleate trophoblast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
CRCGN014_HEPG2_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.72094
GTEX-QDVJ-0626-SM-48U1T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SF-1026-SM-4AD4I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959557
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GRIK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49626
bewo	HPA Cell Line Gene Expression Profiles	1.0	1.07186
Sebaceous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.154
BRD-K90027355_spironolactone_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
decamethonium bromide-7353	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A19633847_PERHEXILINE MALEATE_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K36737713_AG 957_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TTI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20149
Endometritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
GTEX-SUCS-1726-SM-32PM8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22766
Acute Myeloid Leukemia_LAML_TCGA-AB-2903-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K85513726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20495
GSE132948,GSE132949_4_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51817
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35332
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30027
Perturb_14391_KD_PAX8_SRP276625	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
oxoacid metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K12613826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09383
NCIH660	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12464
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
maprotiline-5022	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN012_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.672
BRD-K63675182_TRIFLUPROMAZINE HYDROCHLORIDE_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7255-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV504	Achilles Cell Line Gene Essentiality Profiles	1.0	2.08075
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L540	CCLE Cell Line Gene Expression Profiles	1.0	2.04956
SK-N-AS	GDSC Cell Line Gene Expression Profiles	1.0	1.45324
BRD-K70891562_STOCK3S-04022_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
PANC0813	Achilles Cell Line Gene Essentiality Profiles	1.0	1.07248
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.984286
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.941743
GTEX-XBED-0926-SM-48TCE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24082
BRD-K28467592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.79568
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48691
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100465_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10807
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-0.748764
primary somatosensory cortex (area S1, areas 3,1,2)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20307
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K59058766_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
genistein-1073	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.871638
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.988199
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE212312_2_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K27me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K11251396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12369
BRD-K06623064_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
Perturb_17806_KO_ZNF675_SRP304971	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.54349
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.47945
15735049-Table2	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-4477b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K50216176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58704
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.95418
primary visual cortex (striate cortex, area V1/17)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34316
GTEX-SNMC-1626-SM-4DM52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23327
BRD-A70514680_Articaine hydrochloride_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A41692738_TGX-221_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02554
BRD-K15409150_penfluridol_NCIH1694_6.0_h_30.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
BRD-K14087001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21586
GTEX-QDT8-0226-SM-32PL4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K06335600_tizanidine_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_12149_KO|OE_TP53|CENPA_ERP125655	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.97037
TBP	ENCODE Transcription Factor Targets	1.0	null
BRD-K24864035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09268
pilocarpine-5341	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Eye	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.433
CRCGN017_MCF10A.TP53.M_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.97675
BRD-K36197756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35991
Perturb_7887_Mut_RPB6_SRP305464	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.992
MSX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03053
CRCGN013_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65581
Perturb_546_KD_EF1_SRP201842	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
posteroventral (inferior) parietal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20068
chylomicron	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.385436
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882782
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.0069
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00873
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_2022_KO_Kmt2c_SRP283007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.51739
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.951378
BRD-K35230457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12134
posteroventral (inferior) parietal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.856457
IRF1	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.WT.HP_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01368
Perturb_6630_KO_TEAD1_SRP315348	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.24543
BRD-K20259776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58343
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE139540_0_v_1_menadione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TRAPP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.574
GSE147366_3_v_2_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
monocarboxylic acid transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Fast twitch muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
U251	GDSC Cell Line Gene Expression Profiles	1.0	1.70349
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838935
hsa-miR-577	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE114992,GSE114993_7_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Conceptus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.591
inner CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.988239
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-570-ENSG00000061455_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.01201
PARK7_KD_GDS3750_2_human_SH-SY5Y	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.824404
CRCGN010_HEPG2_24H:D02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20158
VPS13C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0058416
CRCGN011_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.0823
BRD-K82440152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22731
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.827415
BRD-K20373726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19388
Perturb_548_KO_SA2_SRP201842	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.01937
HPAFII	DepMap CRISPR Gene Dependency	1.0	9.42888
Perturb_599_OE_HOTAIR_SRP342161	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.07383
GTEX-SIU7-1326-SM-4BRWW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918664
acetyl-CoA carboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.281
PMC7062471-elife-52504-supp6.xlsx-TEAD4_motif_in_OCR_around_DEGs-Gene_ID_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WK11-0626-SM-3NMAV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47621
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K55946794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2078
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055891
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39336
SRCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54436
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-RELA_DN_V1_UP-Gene_name_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
PSMB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24695
Hyperplasia	CTD Gene-Disease Associations	1.0	1.38298
MZ in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.891565
BRD-K61206648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68664
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X62O-1626-SM-46MW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Transport of fatty acids	Reactome Pathways 2014	1.0	null
GTEX-VUSG-1126-SM-4KKZQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12884
BRD-K84158675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31266
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
tanespimycin-6944	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Perturb_15455_KD_E2F1_SRP165775	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.62107
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Choriocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.018
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03439
BRD-K19220233_-666_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE140965_2_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MN-0926-SM-32PLX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998438
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBJ-2026-SM-3NB1R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833517
Liver hepatocellular carcinoma_LIHC_TCGA-ES-A2HT-11A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.271728
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35812
GSE147943_4_v_6_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K94518115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.57262
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE242049_1_v_0_txndc5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81418486_vorinostat_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN012_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30247
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Embryo Loss	CTD Gene-Disease Associations	1.0	1.16104
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25007
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.91314
Uterine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
BRD-K19264579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04214
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Left ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.211
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31393
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.53451
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041312
Perturb_10656_OE_Gdf2_SRP244969	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.7326
SUZ12	ENCODE Transcription Factor Targets	1.0	null
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K05796207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24892
TMEM50A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04414
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
very long-chain fatty acid-coa ligase activity	GO Molecular Function Annotations 2015	1.0	null
Hemorrhage	CTD Gene-Disease Associations	1.0	1.22696
BRD-K98404142_16beta-Bromoandrosterone_SNGM_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-NPJ8-1726-SM-2YUNB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966562
GTEX-T5JC-0326-SM-4DM5C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
Appendicular lean mass	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.25229
GSE173232_2_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K09117810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15021
pineal_day	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.3079
Death, Sudden, Cardiac	HuGE Navigator Gene-Phenotype Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KW-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
pimethixene-7426	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.596
RERFGC1B	CCLE Cell Line Gene Expression Profiles	1.0	2.05357
Perturb_13953_OE_lncNR2F1_SRP179994	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.02682
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
BRD-K29905972_S1005_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4853
LYRM7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00689045
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56288
GSE180200,GSE180201_2_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24552
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.904
BRD-K37527826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92021
BRD-K66754362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4325
Weight Loss	CTD Gene-Disease Associations	1.0	1.20719
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829287
BRD-K88679751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07871
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15259298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24963
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.20248
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1081
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Benign familial infantile epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867083
GTEX-U8XE-1926-SM-3DB98	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K04399953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0248
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CGTH-W-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2634
CLPTM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06512
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25305749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15174
TNFAIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24047
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
PMC6757314__F3	PFOCR Pathway Figure Associations 2023	1.0	null
prasterone-5019	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FDFT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00285199
GTEX-XPVG-2926-SM-4B66G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-RUSQ-1926-SM-2TF6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE171401_1_v_0_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2945
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
JEG-3	GDSC Cell Line Gene Expression Profiles	1.0	2.13132
PMC7281309-mmc16.xlsx-Supplementary_Table_14-Supplementary_Table_14_Differentially_expressed_genes_in_H1819_after_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16882
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
CP67-MEL	GDSC Cell Line Gene Expression Profiles	-1.0	-1.62669
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992345
CRCGN016_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8069
YIPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12716
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	1.12446
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.093
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3005
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95325
BRD-K66383189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95219
GSE123825_0_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SKG-IIIA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_5209_KO_DICER1_SRP141147	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.43804
496100401_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.13364
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.35304
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.54857
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K26423054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16257
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	1.0	null
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30496
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	1.0	2.34412
GTEX-WFON-0926-SM-4LVMK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9578
DIDO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00696185
GSE116299_0_v_1_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
BRD-K43405658_AG 527_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825836
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.17
GSE143316_0_v_6_somatostatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6936-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K99413603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30015
GSE192663_1_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U4B1-0226-SM-4DXU8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-VUSG-0626-SM-4KL1Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.8646
bisoprolol-5348	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Endometrial Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K71093375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29196
OAW28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71667
SLC22A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00597297
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81811
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K55538850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13139
GSE246053_4_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Perturb_547_KO_SA1_SRP201842	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.74088
Perturb_380_KD_TOP1_SRP295687	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.94772
Adrenocortical carcinoma_ACC_TCGA-OR-A5KX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
MFE-296	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC30A7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00761962
LPCAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01102
BRD-K87909389_F3055_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Perturb_15110_KD_PPHLN1_SRP218207	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.72388
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.35763
GSE146982_4_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U8XE-0826-SM-4E3J1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-T2YK-0326-SM-4DM7D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878243
GSE128634,GSE128636_2_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hereditary spastic paraplegia 42	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
PRR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00501
GTEX-QDVN-0226-SM-48TZ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.78181
GSE100316_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17645
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.953906
BRD-K78513633_Lonidamine_SNGM_6.0_h_177.6_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LN340	Achilles Cell Line Gene Essentiality Profiles	1.0	1.05494
15902281-TableS1e	GeneSigDB Published Gene Signatures	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
long-chain fatty acid import into cell	GO Biological Process Annotations 2025	1.0	null
tamoxifen_homo sapiens_gpl3921_gse33366	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
GTEX-XUZC-0226-SM-4BOO7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856447
KG1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84332
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.904406
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
chr5_128965518_A_G_b38	GTEx eQTL 2025	1.0	1.32433
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.26794
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XUJ4-0126-SM-4BOP7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942502
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_12580_OE_STK32B_SRP261296	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.65157
HL60	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53023
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_14903_KO_PRMT6_SRP125977	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.70234
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
Palmitic acid	HMDB Metabolites of Enzymes	1.0	null
BRD-K77830450_forskolin_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC35A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61215
PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
syndrome	GeneRIF Biological Term Annotations	1.0	null
Peroxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.135
diphenhydramine-1708	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S95S-0726-SM-4B64H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Atrial fibrillation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.395
BMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70986
BRD-K81418486_vorinostat_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G2_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.98279
BRD-K66985689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6521
PMC11223007-Supplementary_Data.pdf-28-THAP12_THAP12	Rummagene Transcription Factor Associations 2026	1.0	null
Matrix fibroblast_Lung_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Cervicovaginal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
GSE225656_2_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K61687409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44365
BRD-K17570530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5927
olfactory part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31286
GTEX-VJYA-0626-SM-4KL1S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09595
KANK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00613437
GSE175787_11_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239578_0_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:D03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14717
GSE112860_0_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.836958
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90133009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21503
BRD-K29144638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42005
GTEX-QCQG-0126-SM-48U27	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07698
GSE126402_5_v_3_tal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ppar signaling pathway	KEGG Pathways	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BICR 10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04019
BRD-K08262651	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07867
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61045
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-1526-SM-4LMIG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13685
Ost-alpha/Ost-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.824
BRD-K55939029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50399
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7647
BRD-K07396550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44552
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	3.0036
BRD-K64985742_7826208_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_4849_KD_ZEB2_SRP059197	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.87516
Edema	CTD Gene-Disease Associations	1.0	1.04757
foliosidine-3636	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
18794137-SuppTable1d	GeneSigDB Published Gene Signatures	1.0	null
496100412_FWM_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.42813
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.9872
BRD-K28448768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04545
GTEX-XUZC-2026-SM-4BRW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K97641878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42812
BRD-K93186184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.70072
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Gestational diabetes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.643
LY-294002-5937	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AM38	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.52636
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18566
Perturb_2023_KO_Kmt2c_SRP283007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.52287
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0573
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1966
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
ANKRD35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19896
ARHGEF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14903
Nerve - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	1.43766
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HS766T	Achilles Cell Line Gene Essentiality Profiles	1.0	1.64875
SNU1033	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.47001
BRD-K94775036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04907
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MET_knockout_263_GSE8747	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.23988
mediodorsal nucleus of thalamus_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06595
carboxylic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K99074976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28916
equilin-5255	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_537_KD_MYBL2_SRP161768	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210101,GSE210114_6_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12454715-13555_2025_1471_MOESM1_ESM.pdf-89-LEF1_LEF1	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.12343
ventral posterior lateral nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.836903
17192395-TableS2c	GeneSigDB Published Gene Signatures	1.0	null
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040498
BRD-K80546581	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32871
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.11933
GTEX-WYJK-1426-SM-3NM8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K36644177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34999
Amino acid transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.754
SP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.867011
estradiol-6928	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K19624190_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
RCM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16329
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062948
NSFL1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5058
MEK_INHIBITION_GDS5029_278_human_SW480 KRAS-mutant colorectal cancer cell line - 4hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_2-1769_genes_are_more_than_four-fold_upregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H661	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XV7Q-0726-SM-4BRV6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849847
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.255
respiratory function tests	GAD Gene-Disease Associations	1.0	null
BRD-K98682310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13311
GTEX-WH7G-0626-SM-4LVMO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-RU1J-0426-SM-46MUK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29184
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08359
GSE147943_5_v_1_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1569	CCLE Cell Line Gene Expression Profiles	1.0	1.83965
Ichthyosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-P78B-1926-SM-3P616	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11523
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K98521173_Deoxycorticosterone_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE146982_4_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-DX-A6BA-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gestational Diabetes	DisGeNET Gene-Phenotype Associations	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3788
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15345
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
MACROH2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49264
GSE58724_3_v_0_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.924449
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Alfuzosin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
CRCGN017_MCF10A.WT.HP_24H:C02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17461
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RVH421	DepMap CRISPR Gene Dependency	1.0	3.81335
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.74394
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QG-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ3S-0626-SM-4BOOB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882068
Prostatic Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.419623
GSE192513,GSE192515_2_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
long-chain fatty acid-CoA ligase activity	GO Molecular Function Annotations 2025	1.0	null
GSE119345_2_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
Metabolic Syndrome X	DisGeNET Gene-Disease Associations	1.0	null
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28531
BRD-K45245001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40821
chr5_128920894_A_T_b38	GTEx eQTL 2025	1.0	3.85015
GSE173873_8_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33164
BRD-K35852282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36585
lateral nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.884822
BRD-K22229373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33962
BRD-K62459624_T5212475_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.836268
BRD-K66821167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08989
BRD-K83238251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18846
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14424
CRCGN010_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00349
GTEX-XUJ4-1726-SM-4BONW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.968395
KP-N-YN	GDSC Cell Line Gene Expression Profiles	-1.0	-1.52888
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906568
BRD-A79768653_sirolimus_HCC15_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.407073
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_2491_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92679
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
pathogenesis	GeneRIF Biological Term Annotations	1.0	null
BRD-K31883758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89749
PMC4241130__F2	PFOCR Pathway Figure Associations 2023	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS172T	CCLE Cell Line Gene Expression Profiles	1.0	2.03931
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_neg_targets-ID_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.299569
BRD-K98639224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5292
probucol-5261	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.48038
GTEX-TML8-1426-SM-4DXUT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04317
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K90049800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36267
Perturb_9407_KD_GATA6AS_SRP279802	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.02142
Adrenoleukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.644
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56301217_A112550.cdx_VCAP_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15573
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01014
GTEX-XQ8I-1626-SM-4BOOI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03258
BRD-K17674993_Diflorasone Diacetate_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K13627844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31731
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36987
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K85985071_E3380_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
acetylsalicylic acid-6964	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-590-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
BRD-K39484304_triptolide_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K75041300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07541
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32075
BTF3P11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00585001
HCC1954	Achilles Cell Line Gene Essentiality Profiles	1.0	1.03824
valproic acid-1047	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
pancreas_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
C32	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.4041
L-540	GDSC Cell Line Gene Expression Profiles	1.0	1.7293
GSE165682_4_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lipid transport	GO Biological Process Annotations 2015	1.0	null
GSE146072_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69855
CPLANE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9883
Uterine luminal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.696
Pentadecanoic acid	HMDB Metabolites of Enzymes	1.0	null
moroxydine-5304	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SW872	GDSC Cell Line Gene Expression Profiles	1.0	3.16523
BRD-K47170544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17539
cardiac muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.589234
AZ521	CCLE Cell Line Gene Expression Profiles	-1.0	-2.0541
Perturb_9661_KD_circTTN1_SRP260174	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4719
GSE221004_1_v_2_prdm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7523182-Table_2.XLSX-Lipid_metabolism_pathways-NFYA_NFYA	Rummagene Transcription Factor Associations 2026	1.0	null
Prestwick-983-7480	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WS-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09117
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19699
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.40714
BRD-K31992830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47479
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.02671
FAM169A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09881
NHP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08869
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.66298
UQCRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0351
BRD-K99824630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16279
BRD-K38477985_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
azacyclonol-1520	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain morphology (MOSTest)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
CRCGN011_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5251
GSE190384,GSE190386_0_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64514
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39431
BRD-K20028052	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3664
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.41728
BRD-K23342427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03297
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57424
AUTS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00584412
GSE171837_0_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K06543683_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23541
Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08834
BRD-K30312557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06264
BRD-K87909389_HY-10005_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K86797399_pracinostat_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.894002
GSE58724_1_v_4_oxymetholone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
prochlorperazine-1053	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
clenbuterol-5266	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Umbilical cord blood cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.586
COLO684	CCLE Cell Line Gene Expression Profiles	1.0	1.55728
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0399
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21172
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.854199
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.953697
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.796
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE100316_3_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2BC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04461
H3K27me3_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Fetal Death	CTD Gene-Disease Associations	1.0	1.10527
GSE210101,GSE210114_7_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135686_2_v_3_etomoxir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE112860_0_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Heart ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.211
SBNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3852
CRCGN011_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50755
SNU81	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50006
withaferin A-3902	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTV1DM	DepMap CRISPR Gene Dependency	1.0	3.36422
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091616
BRD-K30853940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18862
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.15752
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0398
Perturb_3142_OE_CXADR_SRP274008	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.30151
GSE143782_3_v_4_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.395
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E4-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63912037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18054
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
Husk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.559
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.926735
GTEX-QEG5-0326-SM-2S1PB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-QXCU-0226-SM-2TC5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Schneckenbecken dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.566
Nuclear outer membrane-endoplasmic reticulum membrane network	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
BRD-K78748401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0738
Perturb_8702_KD_MXD4_SRP374659	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.51989
GSE211262,GSE211263_0_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRX-20693478-ADULT-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC3721393-bjc2013326x2.xls-Breast_Cancer_SOX10_Gene_Sig-Unnamed_1_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12119989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06794
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Prostate adenocarcinoma_PRAD_TCGA-HC-A632-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRX	ChEA Transcription Factor Targets	1.0	null
BCAT_GDS748	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.52001
GTEX-WHPG-2326-SM-3NMBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
YY1	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4225-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K08241590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21238
BRD-K06251362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21316
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24955
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
coralyne-2652	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PIK3C2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81232
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6376
CRCGN008_HEPG2_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11905
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
EXT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00545869
SK-MG-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PWCY-0226-SM-48TD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06974
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.73524
cefotiam-5361	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DEL	CCLE Cell Line Gene CNV Profiles	1.0	1.37023
BRD-K45498945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66742
GTEX-XUZC-0326-SM-4BOO8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02807
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tribenoside-3507	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.915074
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Perturb_8490_KD_CAG/CUG_SRP119324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.4511
BRD-K75100119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26637
GSE239844_11_v_12_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K95153427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28142
PF-00562151-00-6868	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
THRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71734
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNOS-1626-SM-3NMA4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930697
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25122
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839363
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10944
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GSE113385_0_v_1_six1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-W5WG-2726-SM-4LMIC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2698
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.1003
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XMK1-0126-SM-4B65F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
CRCGN012_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6729
placenta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.139354
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.764
BRD-K24978625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20737
GTEX-R55G-0526-SM-2TC5O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988509
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27328
SCN11A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00647997
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4P3-0526-SM-4AD58	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13891
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046352
Metabolic Syndrome X	HuGE Navigator Gene-Phenotype Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A879-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWCY-0826-SM-48TCR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16617
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Retina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.433
Night sleep phenotypes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
BRD-K85493820_KM 00927_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MLPH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00613771
Dilated cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
3-isopropylmalate dehydratase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.582
CRCGN014_HEPG2_3H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1308
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.957451
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Perturb_2418_OE_PDE5_ERP011301	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
nifenazone-2285	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K33606137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.32572
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30189
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50386
ebselen-3458	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
proton-transporting two-sector ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.049
18667080-TableS9	GeneSigDB Published Gene Signatures	1.0	null
P2RX7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00460422
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22454
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.09251
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K16485616_mocetinostat_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
PIGW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29544
GTEX-UJHI-1926-SM-3DB8Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
SW1088	CCLE Cell Line Gene CNV Profiles	1.0	1.61461
fatty acid transport	GO Biological Process Annotations 2023	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210101,GSE210114_2_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.254296
Perturb_7314_KO|KD_UPF3A_ERP130416	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.22345
GOS3	CCLE Cell Line Gene Expression Profiles	1.0	1.74972
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43219
ciprofloxacin-5299	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN017_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.54583
monocarboxylic acid transport	GO Biological Process Annotations 2015	1.0	null
chr5_128902447_T_C_b38	GTEx eQTL 2025	1.0	1.2536
L363	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.84247
BRD-K81418486_vorinostat_VCAP_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K73899967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19571
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.30851
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NSC-625987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58942
GTEX-XPVG-0726-SM-4B658	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922676
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
trazodone-7452	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.848478
Cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
BRD-K95334975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39705
BRD-K96379403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13049
GSE145249_0_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
Heart conduction disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.395
organic substance transport	GO Biological Process Annotations 2015	1.0	null
Sebum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.585
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E2-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12443547-DataSheet5.pdf-3-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
Rdw - Red Blood Cell Distribution Width Result	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-WL46-0526-SM-3LK7W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
PMC4815041-NIHMS715090-supplement-Supplementary_Table_10.xlsx-CCF_DP_clustering-Hugo_Symbol_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K80725632_EI-232_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE165682_0_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K26195700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42355
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11566982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13543
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K68202742_trichostatin A_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NSMCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00036
GSE183251_1_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QV44-1026-SM-447CG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11633
GSE241036_0_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Red Cell Distribution Width Determination	DisGeNET Gene-Phenotype Associations	1.0	null
Brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.886
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE112860_3_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
CLCN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44025
Atrial appendage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13381_KO_CTIP2_SRP150394	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.67235
Visceral endoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.715
USP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00532449
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
adult-onset autosomal dominant demyelinating leukodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
Perturb_10212_KD_SETX_SRP353945	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.1828
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22449
BRD-A23955117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43486
GTEX-OIZF-1526-SM-3MJGY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62226
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.958981
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.175
PMC5013636-ncomms12601-s5.xlsx-TCF3-Groups_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3422654__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.866382
VPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25651
lateral posterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.825095
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55037
IMR-5	GDSC Cell Line Gene Expression Profiles	-1.0	-2.2454
breast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078937
GSE123825_0_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
genistein-5232	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_16116_KO_MESP2_SRP153048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.09829
Peroxisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.022
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IU-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074005
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_8881_KD_CSL_SRP142324	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.99691
Perturb_14388_KD_PAX8_SRP276625	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.99437
BRD-K54789622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16777
GTEX-V955-1026-SM-4JBHO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3685
CP66-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K08751619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01144
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21402
hsa-miR-4287	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-U4B1-0926-SM-4DXUV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3514
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43861
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.124251
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.177804
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
TFAP2C	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K66577743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45129
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.98396
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.317182
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K44549496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70566
BRD-K38615104_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
umbilical cord blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.527534
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-C1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882996
tretinoin-991	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08068
BRD-K08558441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01419
mRNA_GADD45A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K07979116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94334
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4887
BRD-K91354770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32646
BRD-K80381603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08799
NCIH2085	CCLE Cell Line Gene Expression Profiles	1.0	3.40767
BRD-K15474464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33599
GSE100316_7_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AGBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25004
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K33748896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15954
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K93044218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58531
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.77543
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-T8EM-0426-SM-4DM7E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
JAR	GDSC Cell Line Gene Expression Profiles	1.0	2.42955
Perturb_15203_KO_HOXA13_SRP316008	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.46046
GSE213588_10_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
QRICH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.095
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K08715918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63504
Longissimus thoracis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.655
BRD-K27406233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39379
Perturb_14147_KD_RCOR1_SRP279638	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.11919
Transport of small molecules	Reactome Pathways 2024	1.0	null
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.853342
GSE195663_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217405_0_v_1_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM266	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.005711
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SNU283	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73801
PMC6870463-Table_7.xlsx-Family_H_LPS-LPS_treatment_of_BMDMs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Longissimus cervicis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.151
BRD-K06816455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26783
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88486
prochlorperazine-1640	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171401_1_v_2_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sacrospinalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.611
PRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82182
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.142402
BRD-K23208879	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03522
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824262
BRD-K78126613_MENADIONE_RKO_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE155031_5_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Fetal Growth Retardation	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K48332223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.64376
cognitive disorder	GWASdb SNP-Disease Associations	1.0	1.1395
orbital frontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41916
GTEX-XGQ4-2526-SM-4AT57	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896524
GSE205163,GSE205164_5_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K44167510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43105
organic acid transport	GO Biological Process Annotations 2015	1.0	null
HCC2157	CCLE Cell Line Gene Expression Profiles	1.0	1.88459
BRD-K96448434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25649
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
GSE216043_11_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U4B1-1926-SM-3DB9E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_4759_KO_DLG2_SRP315088	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.32374
chh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08327
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
halcinonide-6040	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059887
CP66-MEL	GDSC Cell Line Gene Expression Profiles	-1.0	-1.67726
GTEX-XAJ8-1226-SM-47JYS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-OXRP-2426-SM-2S1NR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE239578_5_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.30383
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0532
BRD-K69521416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08188
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.94
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.41844
hsa-miR-4685-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-WYJK-0526-SM-3NM8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849843
GSE100316_3_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88989
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S33H-1326-SM-4AD6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925137
BRD-K86269644_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1885
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
outer CP in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36973
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.54312
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-WFON-0526-SM-4LVLY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.988635
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.71194
BRD-K06330738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02704
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825836
SHP-77	COSMIC Cell Line Gene Mutation Profiles	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
CRCGN014_HEPG2_3H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.457
harmaline-2805	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IGR39	CCLE Cell Line Gene CNV Profiles	1.0	1.64259
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FRS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00371
GTEX-X5EB-1026-SM-46MVU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6008
Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19501975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31002
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K24132293_piperlongumine (HPLC)_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PX3G-0326-SM-2I3EO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913549
GTEX-P4QT-1326-SM-3NMD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979261
BRD-K66748326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15068
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61377
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
18974375-TableS5a	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886049
placenta	HPA Tissue Protein Expression Profiles	1.0	1.19684
Perturb_11700_KO_RB1_SRP315915	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.1408
GSE174701_1_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SE-0526-SM-2XCD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Atrophy	CTD Gene-Disease Associations	1.0	1.20097
Perturb_478_KD_PPARGC1A_SRP278736	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.17222
GSE210101,GSE210114_11_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.07086
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07548
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EZ-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RU1J-1026-SM-46MUR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
C17orf97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04491
binding	GO Molecular Function Annotations 2015	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.412011
BRD-K94616959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75123
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956224
Prostate adenocarcinoma_PRAD_TCGA-EJ-5516-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95264594	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19976
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.63273
BRD-K60780031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84636
GTEX-R55G-0926-SM-48FDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963782
GSE163862_1_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00114
BRD-K68438316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48277
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K73162352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77391
Perturb_14017_KD_PGBD1_SRP398441	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.457
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.23501
Perturb_545_KD_CT_SRP201842	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
hnf4a_21852396_wao9_lof_human_gpl570_gds3926	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.179675
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4390530-NIHMS667786-supplement-1.xlsx-Sheet1-Supplementary_Table_2_Genes_closest_to_AR_induced_ASH2L_peaks_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_15460_KD_CSN5_SRP316687	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.15151
CRCGN008_HEPG2_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4066
BRD-K43292469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05099
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.846476
wortmannin-911	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WZTO-1326-SM-3NM8X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62328
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
MCF7	CCLE Cell Line Gene CNV Profiles	1.0	2.03806
BRD-K22668106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74156
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Twitch muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890447
GTEX-X5EB-2426-SM-4E3HX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Transmembrane transport of small molecules	Reactome Pathways 2014	1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
DL-PPMP-1121	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K15609977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86385
fluphenazine-5597	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-VJYA-0126-SM-4KL1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00866
Leukodystrophy	DisGeNET Gene-Disease Associations	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
OFD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00564068
BRD-K26758344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00933
glucose intolerance	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.477151
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K07486034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89158
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE211262,GSE211263_2_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
19505326-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
OCUB-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210101,GSE210114_6_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7416-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.15656
GSE217101_0_v_1_mcph1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
d17	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.761
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.63489
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
TC71	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.28328
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AH-0126-SM-48U2B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986982
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_6_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K55070890_thiothixene_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE143643,GSE143644_4_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Systemic primary carnitine deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.189
GSE186287_2_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110524_2_v_5_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K22390389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26139
Pyloric cecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14079
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.50544
BRD-K08043579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74428
JUND	ENCODE Transcription Factor Targets	1.0	null
BRD-K04548931_epirubicin_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06371
BRD-K74148702_curcumin_HA1E_24.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11853856_PJ 34 hydrochloride_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K93153656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16215
trichostatin A-3332	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.03206
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910526
GTEX-PSDG-1426-SM-48TD1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851611
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053032
BRD-K27973265	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08865
G0S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4475
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4540202-cddis2014370x2.xls-Sheet1-Table_S2_MEIS2-responsive_genes_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHU-1326-SM-4E3K7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7819-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.796
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.870352
RARRES1_KD_GDS4818_314_human_SUM149	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE146982_0_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE241036_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MM1S	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.46482
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Optic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.614
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-515-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
496100376_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.41642
Perturb_15442_KD_MED25_SRP212208	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.08386
UMUC16	DepMap CRISPR Gene Dependency	1.0	5.28056
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
apomorphine-5283	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00455
BRD-K84388444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55314
Heart Failure	DisGeNET Gene-Disease Associations	1.0	null
GSE118077_4_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE85880,GSE85881_4_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09968
BRD-K72066653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7166
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.99907
MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE160373_8_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46805
BRD-K79730625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91702
ethotoin-6052	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12628
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_14328_KD_GRHL2_SRP157074	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.49088
GTEX-SIU8-0426-SM-4BRUE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.77
BRD-K85741537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77318
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.901
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20726
BRD-K14328427_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7438-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K90027990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26578
indoprofen-4832	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AMP-binding enzyme C-terminal domain	InterPro Predicted Protein Domain Annotations	1.0	null
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4206
Perturb_2986_KO_BAP1_SRP108473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	19.3979
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.193836
H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4153
carboxylic acid transport	GO Biological Process Annotations 2015	1.0	null
BRD-K98749544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41676
GSE160373_6_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84
Tridecanoic acid	HMDB Metabolites of Enzymes	1.0	null
Perturb_6200_KO_Firre_SRP076940	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.74532
triprolidine-7008	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cellular lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-O5YV-0426-SM-3LK66	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K67874412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13464
CRCGN010_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82498
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.905574
GTEX-TMMY-0526-SM-33HBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16759
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3146
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A34774643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39423
Perturb_4852_KD_ZNF503_SRP059197	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.76262
GTEX-NFK9-0526-SM-2YUNL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19967
BRD-K16935435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10039
long-chain fatty acid transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
GATA2_01_61	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.40125
RELA_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
GSE103309_2_v_0_ube3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OIZH-3026-SM-3NB1G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K43284834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50391
HIPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08407
Perturb_13604_KD_YAP1/WWTR1_SRP221804	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.901146
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
BRD-K51446586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39896
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053196
BRD-K43620258_3,5-dichloro-2-hydroxy-N-(2-methoxy-5-phenylphenyl)benzenesulfonamide_LOVO_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE116299_0_v_3_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K31354456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08357
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAMOS-2G6-4C10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Serotonergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.614
BRD-K18657361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10361
18794137-SuppTable1a	GeneSigDB Published Gene Signatures	1.0	null
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983994
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10027
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A876-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7924-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.848722
JVM-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.48268
SPTAN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00463497
Creatine kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52772
BRD-A19037878_trichostatin A_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AGTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69208
type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.219398
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K05561348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14718
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Atrial Fibrillation	DisGeNET Gene-Disease Associations	1.0	null
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10175786-Table4.XLSX-Sheet_1-GSE9750_AND_GSE63514_NOT_GSE7410_NOT_Ferrotosis_genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ESR1-22446102-UTERI-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
LIM1215	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HDQP1	CCLE Cell Line Gene Expression Profiles	1.0	1.82671
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Psoas major	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.594
18801183-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064188
urinary bladder	HPA Tissue Protein Expression Profiles	-1.0	-0.748764
CRCGN010_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3006
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07632
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FGFR3_KD_GDS4454_78_human_RT112	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.942
Basal plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.588
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K82068522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68777
anterior (rostral) cingulate (medial prefrontal) cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.965786
Perturb_7752_KD_YTHDF2_SRP155278	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.13457
BRD-K98249237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05304
GSE149943_1_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240027,GSE240030_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131161_2_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55607
BRD-K40206099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10771
CRCGN008_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.059
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.711122
BRD-K70549064_EI-156_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mammary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.261
GSE123825_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
Lung squamous cell carcinoma_LUSC_TCGA-77-A5GH-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03918
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0164
AQR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26224
MBIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48839
GTEX-RU72-0326-SM-2TF5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895001
BRD-K81575721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94101
BRD-K75076471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40238
LY-294002-1007	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903118
SLC7A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15776
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.12265
GTF2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36867
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.811356
Microvillus membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.187
CTBP2	ENCODE Transcription Factor Targets	1.0	null
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48722
SIN3A	ENCODE Transcription Factor Targets	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Perturb_8355_KO_ZCCHC4_SRP345783	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.49781
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.855854
BRD-K35472285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22884
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE125153_1_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K33462260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18791
GSE112860_0_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.876
PMC8481886-Table_1.xlsx-A_subsets-bone_marrow_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K46655163	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22679
Hair follicle epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.421
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0252
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.11571
MEL270	DepMap CRISPR Gene Dependency	1.0	2.33943
Response to fenofibrate (total cholesterol levels)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
ZNF560	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14914
TCF4	ChEA Transcription Factor Targets	1.0	null
EFO-21	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
geldanamycin-593	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Subcutis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.542
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.76175
PHGDH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00416076
CRCGN012_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.98939
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K39020351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2503
GTEX-P4PQ-0726-SM-3NMCR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85808
BRD-K48195722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2695
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
imatinib_homo sapiens_gpl96_gds3048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8519939-41525_2021_248_MOESM5_ESM.xlsx-RELA_DN_V1_UP-Ensemble_gene_ID_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TJAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29394
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.266069
BRD-K51572611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25547
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K60946512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53889
PMC9307901-mmc2.xlsx-S5-GATA6-AS1_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.433
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.969114
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE113106_0_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.05265
BRD-K12862541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50378
GSE195559_6_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123825_2_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09684
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BeWo cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.201
cognitive impairment	GWASdb SNP-Phenotype Associations	1.0	0.995928
BRD-K03476091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18998
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PPAR signaling pathway	KEGG Pathways 2026	1.0	null
BRD-K67769696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42565
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7423-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of higher mental function	GWASdb SNP-Phenotype Associations	1.0	0.310451
496100664_HIP_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.81568
GSS	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80249
GSE168807_6_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
tanespimycin-6937	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
acetylsalicylic acid-984	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE210101,GSE210114_5_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
(+)-chelidonine-6236	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SBK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67399
16818636-TableS2	GeneSigDB Published Gene Signatures	1.0	null
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88407
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.48559
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33229
GRAMD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36321
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
thiamine-responsive megaloblastic anemia syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
GSE180147_0_v_1_itga5_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K05804044_AZ-628_A375_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.946946
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE128634,GSE128636_2_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SYNGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37531
BRD-K96258717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45237
CRCGN009_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0048
Perturb_9657_KD_NKX25_SRP306591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Placental insufficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
BRD-K63410075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.47102
WDR91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31407
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2931-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4371880-12885_2015_Article_1101.pdf-13-SIX2_SIX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S4Q7-0226-SM-4AD5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12355
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6N0-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.831866
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26197
GSE146982_0_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Transport of vitamins, nucleosides, and related molecules	Reactome Pathways 2014	1.0	null
GTEX-QDVN-2326-SM-2S1PF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.42757
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K83276573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5753
PRKDC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00522589
chr5_128970638_C_T_b38	GTEx eQTL 2025	1.0	3.38635
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Trophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.76
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K64751430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44576
single-organism transport	GO Biological Process Annotations 2015	1.0	null
CEP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20643
GSE98898_8_v_1_hoxa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K92513859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45021
GSE121824,GSE121826_0_v_2_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9074
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22791
BRD-K21680192_mitoxantrone_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08068
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.333028
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
long-chain fatty acid transport	GO Biological Process Annotations 2015	1.0	null
Hepatic Cirrhosis_Liver_GSE6764	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.0502
CRCGN016_MCF10A.TP53.M_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31443
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31874
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51790412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17662
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19127
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fatty acid metabolic process	GO Biological Process Annotations 2023	1.0	null
Renal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0
BRD-A71459254_CYMARIN_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
acetazolamide-7461	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2BK12ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE247862,GSE247863_0_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SW1573	CCLE Cell Line Gene CNV Profiles	1.0	1.47023
CRCGN011_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.874
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.78052
CTSA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00690646
GTEX-T5JW-1426-SM-4DM5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31837
CRCGN012_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12723
BRD-K60719499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57394
Perturb_7363_OE_RBFOX1_SRP307800	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.0069
TRAPPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11782
Prostate adenocarcinoma_PRAD_TCGA-CH-5740-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40655
BRD-K83466873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14774
GTEX-POMQ-0626-SM-3P61E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01259
Adrenocortical carcinoma_ACC_TCGA-OR-A5JV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K07152092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32396
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.076605
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.045728
PARP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00348012
Muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054043
Perturb_7596_KO_PRPF39_SRP389969	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.4679
BRD-K88447092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02917
bumetanide-7440	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
isotretinoin-7438	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
debrisoquin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22999
PMC11378415-12943_2024_2100_MOESM3_ESM.xlsx-Gland_AdCC_BtoA_ExpUp-MYT1L_MYT1L	Rummagene Transcription Factor Associations 2026	1.0	null
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
GSE131649_2_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.57748
SET2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43459
GTEX-OOBK-0226-SM-2YUMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Plantaris muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
milrinone-7210	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97824
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05984
PMC5746105__F16	PFOCR Pathway Figure Associations 2023	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6938-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_9_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903118
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.96391
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.880133
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.92506
GTEX-S4Z8-0126-SM-4GICC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14616
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.67601
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.76463
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fat cell (adipocyte)_Adipose tissue_Human	CellMarker Gene-Cell Type Associations	1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
bromperidol-2872	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.058293
Restrictive dermopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.539
HDAC1	ENCODE Transcription Factor Targets	1.0	null
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_neg_targets-Gene_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
GSE220520_3_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Allantoic fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
GTEX-RWS6-2426-SM-2XCB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08805
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38539
GTEX-X5EB-1426-SM-46MVW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45221
GSE196699_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K75036062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26074
PMC7479515-mmc8.xlsx-ST-RELA-variable-Unnamed_20_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
carbamazepine-835	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC2157	GDSC Cell Line Gene Expression Profiles	1.0	2.16006
RNF2	ENCODE Transcription Factor Targets	1.0	null
BRD-K78126613_MENADIONE_H1299_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K28952606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59164
GTEX-UPK5-1326-SM-4IHLE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967973
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216043_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
rectum	HPA Tissue Protein Expression Profiles	-1.0	-0.748764
Chorionic villus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.11
BRD-K46805838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44966
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1687
BRD-K88274759	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13522
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42437
Congenital generalized lipodystrophy type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.386273
primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27937
UBTF	ENCODE Transcription Factor Targets	1.0	null
BRD-K77958314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82317
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	2.14188
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LD-01A-12R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spleen_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68083
HMV-II	COSMIC Cell Line Gene Mutation Profiles	1.0	null
polymorphism	GeneRIF Biological Term Annotations	1.0	null
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13002
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-A06276885_N-Benzylnaltrindole hydrochloride_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_14835_KD_Scr_SRP017110	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE85880,GSE85881_0_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
BRD-K45519638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37736
plasma lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.105487
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7369
GTEX-QVJO-0526-SM-447CE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
embryonic kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.312232
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_6_MRC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE89767_6_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WI4N-1126-SM-3LK7Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K45315294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17279
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00579
MCF7	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
GTEX-OHPN-0226-SM-48TBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.482817
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22394
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
Glucose intolerance	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
red.1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.196
Prostate adenocarcinoma_PRAD_TCGA-TK-A8OK-01A-22R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-R53T-1026-SM-48FCO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3222
BRD-K31666794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16899
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TMEM82	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0073748
IL21R	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00712722
GSE120200,GSE127269_1_v_2_asxl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
PR interval	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14875
GTEX-SSA3-0426-SM-32QPI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-QESD-1526-SM-2S1QT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
PMC3422654__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37287
GTEX-PX3G-0726-SM-48TZT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04675
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Obesity	DisGeNET Gene-Disease Associations	1.0	null
GTEX-V955-2626-SM-3NM9F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Perturb_13011_KO_ALOX5_SRP367905	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.23959
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.085347
Perturb_9111_OE_FOXO1A3_SRP188991	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.91575
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19702
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
5-8F cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.049
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7103-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ion transport	GO Biological Process Annotations 2015	1.0	null
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18578
BRD-K56343971_PLX-4032_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE137653_4_v_0_siglecf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-O5YT-0726-SM-3MJHA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14068
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13627
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP-independent citrate lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.027
GSE125025_2_v_3_lyl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6959-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fatty acid ligase activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-RVPU-1526-SM-47JXQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
chr5_128987653_T_G_b38	GTEx eQTL 2025	1.0	1.68055
BRD-K93335719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62831
BRD-K16195444_Oxymetazoline hydrochloride_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K23644387_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Glucose transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.618
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.929054
Perturb_9570_KD_CDH11_SRP318732	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.3198
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6116
Mastitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
GSE132948,GSE132949_4_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2811
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3949
SIRT6	ENCODE Transcription Factor Targets	1.0	null
BRD-K29200961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16452
GTEX-WCDI-0426-SM-4GIAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Microfibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.896
BRD-K17349619_HLI 373_NCIH1694_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
raloxifene-6235	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
carisoprodol-4955	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K45296539_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18193
IL1R1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00551177
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OACM5-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K88573743_A443654_HEPG2_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
single-organism localization	GO Biological Process Annotations 2015	1.0	null
GTEX-XBED-0526-SM-47JY3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11763
SNU489	CCLE Cell Line Gene CNV Profiles	1.0	1.41578
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-XUW1-1526-SM-4BOOY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838882
GTEX-XV7Q-0005-SM-4BRWI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825836
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19048
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NF-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195743_3_v_2_lhx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Endoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39848
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6324
GTEX-U3ZM-0326-SM-4DXUJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-PLZ6-0126-SM-48TC6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60481
GSE114992,GSE114993_8_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MG63	CCLE Cell Line Gene CNV Profiles	1.0	1.37918
CLDN1_OE_GDS3510_393_human_CL1-5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K69650333_idarubicin hcl_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
picrotoxinin-2816	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CAL-51	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
GSE211744_7_v_4_gdf15_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
CHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCDC43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04998
CRCGN013_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.75802
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TH-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFP90	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09197
IZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03344
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
Perturb_14385_KD_PAX8_SRP276625	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.17237
GSE210101,GSE210114_7_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K83436911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09116
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868685
GSE112174_5_v_7_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OIZH-1826-SM-2YUNP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K05329107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33401
GTEX-XUW1-0726-SM-4BOP5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-A20018680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45056
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.29375
NDUFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08574
GTEX-POMQ-1426-SM-3P61D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844364
Slow twitch muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.095
IFNAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06963
NCIH1568	CCLE Cell Line Gene Expression Profiles	1.0	2.39379
omeprazole-2828	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary motor cortex (area M1, area 4)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.506
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50162138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76601
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.26837
hsa-miR-452	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MW-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
myocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.521617
BRD-K36740062_HY-70044_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K68733377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26866
Glioblastoma proneural subtype	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13952
BRD-K72135530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36349
GTEX-X4EP-0726-SM-3P5YJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989619
BRD-K34701680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25322
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.91831
CRCGN009_HEPG2_24H:A15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.17799
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6102
BRD-K68143200_NSC 95397_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K28030757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29228
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A25337146_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CLDN1_OE_GDS3510_31_human_CL1-5 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K74512976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26734
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.871937
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_3_SED-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
CELA2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00575716
BRD-K83213911_PF 750_H1299_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
fatty acid transport	GO Biological Process Annotations 2025	1.0	null
EJM	DepMap CRISPR Gene Dependency	1.0	4.90831
CRCGN016_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89939
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6302_KD_JMJD1A_SRP248223	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.52928
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.13484
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18432
BRD-A52530684_DOXORUBICIN_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RETREG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00531328
496100396_HIP_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58674
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFKB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4074
LAS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20061
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K61831307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23246
GNB2L1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE161295_4_v_3_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_15118_KD_DNMT3A_SRP054246	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.2612
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.051739
BRD-K87573634_10008841_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZC3H10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52439
SBK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03476
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
2-iminoacetate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.737
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-POMQ-2126-SM-2S1OJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
troglitazone-1070	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K15563106_-666_HCC15_6.0_h_177.6_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE192513,GSE192515_1_v_0_atg16l1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K51697315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41196
Sertoli cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K32019201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13891
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60636
BAK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00634752
GSE166169_1_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10202654-mmc3.xlsx-MSC_markers-COMMON_MSC_MARKERS_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7412812-13059_2020_2115_MOESM11_ESM.xlsx-All_EZH2-Upregulated_in_SERBP1_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.908072
Perturb_9064_KD_POU5F1_SRP100928	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.31436
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
salivary gland	HPA Tissue Protein Expression Profiles	-1.0	-0.748764
BRD-K66282601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86634
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22539
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.831932
GI-ME-N	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53995
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Perturb_9061_KD_NANOG_SRP100928	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.71327
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.986055
GSE216273,GSE216292_0_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nasopharynx epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LOVO	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86398
GTEX-SJXC-0226-SM-2XCDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
prostate	HPA Tissue Protein Expression Profiles	-1.0	-0.748764
decreased grip strength	IMPC Knockout Mouse Phenotypes	1.0	null
CRCGN009_HEPG2_24H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3978
RCM1	DepMap CRISPR Gene Dependency	1.0	21.4297
PAX3	ChEA Transcription Factor Targets	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HAND1_cust_neg_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205163,GSE205164_1_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129244_3_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.96517
BRD-K17609687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64513
PMC7479515-mmc4.xlsx-ST-RELA-variable-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
SNU81	DepMap CRISPR Gene Dependency	1.0	2.48839
BRD-K65464642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18072
GP2D	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57101
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4422	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	149.243
Norwalk Virus_HG23_19515767_GSE15520	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.41863
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.913657
ri1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE132948,GSE132949_0_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dyclonine-7423	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24275
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4877_OE_BANCR_SRP135857	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.24754
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053914
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910798
all	GWASdb SNP-Phenotype Associations	1.0	0.032708
FLI1-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Carcinoma, Basal Cell	DisGeNET Gene-Disease Associations	1.0	null
PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.83523
Perturb_9698_KD_SMARCB1_SRP279089	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.36173
GSE130396_7_v_6_braf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	142.092
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01352
BRD-K01978082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57159
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09684
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-11A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05833
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K55584718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25891
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.86165
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-WH7G-1026-SM-4LVML	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974392
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K48922193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01419
CAPAN1	DepMap CRISPR Gene Dependency	1.0	3.51537
hsa-miR-26b-5p	MiRTarBase microRNA Targets	1.0	null
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
RFC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01961
JJ012	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04019
BRD-K09778810_FGIN-1-27_TYKNU_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
posterior (caudal) superior temporal cortex (area 22c)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.93789
GTEX-QLQ7-1826-SM-2S1R5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859743
BRD-K47275094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5616
tacrine-5297	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
anion transport	GO Biological Process Annotations 2015	1.0	null
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K87947369_VX-680_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11631
Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.78779
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-0226-SM-4GIDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
long-chain fatty acid metabolic process	GO Biological Process Annotations 2025	1.0	null
LC-2-AD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PFSK1	DepMap CRISPR Gene Dependency	1.0	3.54248
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A1QS-01A-61R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65598536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41242
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K31215362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23203
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-XBEC-1226-SM-4AT65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924253
GTEX-WFON-1926-SM-3LK7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.247
PMC11266089-Table3.XLSX-Fig1_Disease_targets-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE110268_0_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.63832
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8062-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7920-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14841_KD_GCM1_SRP358680	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.40271
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.911186
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
BRD-K72238567_656402-250MG_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_4760_KO_DLG2_SRP315088	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
PEER	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56097
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.83163
GTEX-V1D1-1126-SM-4JBHT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06205
Perturb_13183_OE_Cry2_SRP303502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.43682
GSE151494_1_v_4_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S32W-1026-SM-4AD5W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36116
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
(+/-)-catechin-4837	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-S33H-2326-SM-2XCB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10241
GTEX-XBED-0726-SM-4GIAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Perturb_14127_KO_TP53/CDKN2A/PTEN/NF1_SRP258861	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.07248
PMC4192274__F2	PFOCR Pathway Figure Associations 2023	1.0	null
PSMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48541
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	2.92315
Perturb_9659_KD_SOX11_SRP306591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.00256
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE240027,GSE240030_1_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A22502289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40791
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36281
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.00076
Myocardial Infarction	DisGeNET Gene-Disease Associations	1.0	null
Pectoral muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.914
IL17RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50409
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
levodopa-4394	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PUS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83635
BRD-K59207957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22387
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRCA1_DEPLETION_GDS2189_121_human_MCF10A mammary epithelial cells (MECs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE128634,GSE128636_2_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-Q2AG-0926-SM-48U1Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
small molecule metabolic process	GO Biological Process Annotations 2015	1.0	null
OCUG1	DepMap CRISPR Gene Dependency	1.0	3.00802
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE86507,GSE86509_0_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SW837	CCLE Cell Line Gene CNV Profiles	1.0	1.7648
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.87123
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.4485
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10679662-mmc3.xlsx-NC-D5-ZEB2-Mutant-Upregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
inner SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.908541
GTEX-U3ZM-0626-SM-4DXTV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1597
GTEX-PSDG-1026-SM-48TCV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
PIP5K1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00414802
BL5423 (ERCC3)	NURSA Protein Complexes	1.0	null
BRD-A56592690_PX12_NCIH1694_6.0_h_30.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052348
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.856567
PPAR signaling	WikiPathways Pathways 2024	1.0	null
PMC11950762-BLOODA_ADV-2024-014354-mmc2.pdf-24-TCFL5_TCFL5	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
P31-FUJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
protein-lipid complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.097538
GSE164505,GSE164506_3_v_1_indisulam_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903734
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056756
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.983483
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K43628610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59357
Heart	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN013_HEPG2_24H:L20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04622
ZNF587B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1085
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.849627
OUMS23	CCLE Cell Line Gene Expression Profiles	1.0	1.66119
H3K9ac_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_3179_KO_ubKDM1A_SRP348808	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.51798
chlorpropamide-3210	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K74148702_curcumin_PC3_6.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
xylazine-4147	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.3397
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.3445
5152487-896	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4742
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K87669186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.43184
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-1526-SM-4DM5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03405
496100638_FWM_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15339
SW626	DepMap CRISPR Gene Dependency	1.0	2.24309
Rumen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.386
SZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15581
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cytotrophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.905
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.12383
GTEX-O5YV-1626-SM-2YUNJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Perturb_7750_KD_POP1_SRP155278	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.75017
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
APAF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00557837
KYSE270	CCLE Cell Line Gene Expression Profiles	1.0	1.49084
GTEX-S4UY-0426-SM-3K2AF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GTEX-SN8G-0226-SM-4DM6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24594
VGLL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00387596
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33164
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0979
BRD-K23762204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02869
long-chain fatty acid-coa ligase activity	GO Molecular Function Annotations 2015	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CRCGN014_HEPG2_3H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9145
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
MIR122_OE_GDS3470_573_human_Embryonic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
traits	GeneRIF Biological Term Annotations	1.0	null
BRD-K64642496_-666_NOMO1_6.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ISL1-27105846-CHIP-SEQ-CPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE175787_11_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
SKRC31	CCLE Cell Line Gene CNV Profiles	1.0	1.44415
BRD-K98087319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25679
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.1431
Brain Lower Grade Glioma_LGG_TCGA-HT-7620-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K33770771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35459
BRD-K90429860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54745
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11471
GSE196699_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Placental membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.003
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Perturb_7740_KO_Yap_SRP281854	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.01041
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48791
CRCGN013_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40745
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEG5-1226-SM-447AR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A216-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE193588_3_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
Chylomicron	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.765
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
breast epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.268137
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-K18519876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24553
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K93215584_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OIZI-1326-SM-3NB1B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09177
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.867083
GSE160246_9_v_7_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
methyldopate-7360	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COLO-800	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-UT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE120216_3_v_0_cbfb_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9942993-pone.0281645.s002.xlsx-non-AR_as_all_as_gained-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K56957086_-666_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-OIZH-0726-SM-3NB1I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36959
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Insulin resistance	KEGG Pathways 2026	1.0	null
BRD-K25675728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42566
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.498388
testis	HPA Tissue Protein Expression Profiles	1.0	0.780938
GSE227592_10_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
triflupromazine-7466	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_11902_KO_Irf8_SRP265303	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.7014
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V1D1-1226-SM-4JBI5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28662
PGM2L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00510222
Loin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
CRCGN014_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.59661
Sarcoma_SARC_TCGA-WK-A8XS-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SKNAS	CCLE Cell Line Gene Expression Profiles	1.0	1.43277
ELAVL1	Pathway Commons Protein-Protein Interactions	1.0	null
PLB985	Achilles Cell Line Gene Essentiality Profiles	1.0	1.49501
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RM2N-0626-SM-48FD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00862
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15345
BRD-K24496482_SB590885_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RAB11FIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51008
Adrenal gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.844831
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
BRD-K57200567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43657
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4437
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AMP-dependent synthetase/ligase	InterPro Predicted Protein Domain Annotations	1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PCI30	DepMap CRISPR Gene Dependency	1.0	2.5649
Perturb_7159_KD_ACTG1_SRP385887	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.75921
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2009	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_4853_KD_NKX25_SRP059197	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.76185
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.61835
GSE85880,GSE85881_0_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OV7	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.02345
BRD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00469773
BRD-K16626032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51672
Perturb_15119_KD_DNMT3B_SRP054246	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.58685
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
PMC7468443-Data_Sheet_2.xlsx-DEG_6h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_1437_KO_Kmt2c_SRP283007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.88732
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.23456
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5X1-0826-SM-3GILN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11704
6-benzylaminopurine-3623	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K03618428_PP-110_A375_24.0_h_22.2_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.52714
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8T8-0326-SM-3DB93	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
PMC6811834-sby183_suppl_supplementary_data_set_1.xls-ZNF804A_DEX_FDR_0_01-Gene_Symbol_ZNF804A	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_18450_KD_H2AFJ_ERP124778	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.1454
glycerol-3-phosphate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.84
CRCGN015_MCF10A_48H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26175
FCRL5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00652503
BRD-K44935022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.72614
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.457725
GSE210580_0_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
promethazine-5317	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Abdominal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.479
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19418
BRD-K93875187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33316
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842956
GSE149075_1_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
EXOSC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28134
very long-chain fatty acid metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K34721572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26572
KYSE-270	GDSC Cell Line Gene Expression Profiles	1.0	1.42907
BRD-K87159315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05633
DNMT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00347439
Prostate adenocarcinoma_PRAD_TCGA-EJ-5496-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hexamethonium bromide-1482	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE122215,GSE122217_5_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909838
Lung adenocarcinoma_LUAD_TCGA-J2-A4AD-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164757,GSE164759_1_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.585534
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4QT-1826-SM-2S1NJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
BRD-A75517195_thiazolopyrimidine_HA1E_24.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE128634,GSE128636_4_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P78B-1126-SM-3P615	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902094
GSE146982_4_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K49577446_flunisolide_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23541
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
organic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.17983
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_5_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K25444802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23947
Perturb_7888_Mut_RPB6_SRP305464	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.66663
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7012
PMC5577301-in-17-237-s001.xls-AR_upregulated_DEGs-Liver_GSE13440_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4676-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE136894_2_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4676-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
M07E	CCLE Cell Line Gene Expression Profiles	1.0	1.39556
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRL-0726-SM-3NM9A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93512
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53903639_480743.cdx_HCC15_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNU1544	DepMap CRISPR Gene Dependency	1.0	2.95418
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-121-PRDM6_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Heptadecanoyl CoA	HMDB Metabolites of Enzymes	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.887302
GTEX-S341-1926-SM-3K2BA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21497
BRD-K15714771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25262
GSE239578_1_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
felodipine-848	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Atrial fibrillation	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.930103
BRD-K35960502_NICLOSAMIDE_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6943-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.3149
Atherosclerosis	DisGeNET Gene-Disease Associations	1.0	null
GTEX-N7MS-0626-SM-2YUN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
Perturb_4761_KO_DLG2_SRP315088	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
ATP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48925
BRD-K17821077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21125
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K72238567_656402-250MG_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Arachidonic acid	HMDB Metabolites of Enzymes	1.0	null
LY-294002-6998	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UACC893	DepMap CRISPR Gene Dependency	1.0	3.37991
BRD-K21176869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.74963
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.892418
CRCGN011_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7635
Perturb_17379_KD_Pparg_SRP190223	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.38749
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08327
CRCGN013_HEPG2_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0951
GSE227592_13_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
superior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.882642
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10394
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.809
CRCGN012_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53174
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6405
NU-DUL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-A52530684_DOXORUBICIN_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-Q2AG-0226-SM-2S1P4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.92364
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05008
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
long-chain fatty acid transport	GO Biological Process Annotations 2025	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.771
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.748764
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22092
BRD-K78126613_MENADIONE_SNGM_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K75281646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80364
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DLST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03412
Sarcoma_SARC_TCGA-IS-A3K6-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oligodendrocyte_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09252
GSE218060_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0126-SM-2TF6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894486
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3586
RUBCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14029
CAOV-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
connecting stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.170287
PHF8	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-0226-SM-4BOPM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843556
FGR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00448053
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71377
GSE115328_6_v_0_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Endoplasmic reticulum subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FGL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00566442
Perturb_9062_KD_POU5F1_SRP100928	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.89529
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
GSE235605,GSE235701_0_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0617
GTEX-S33H-2426-SM-2XCB2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10158
organic anion transport	GO Biological Process Annotations 2015	1.0	null
GSE220914_1_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null