association	dataset	threshold value	standardized value
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Lateral amygdaloid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.067
Frontoparietal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.611
SALL4-22934838-CD34+-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.832
UNCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03863
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_RNF2_22325148	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.965664
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.48684
ZNF711	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91274
Telodendria	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.782
Ankle joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.62
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07511
TUB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55289
MT-CO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78704
Neuronal System	Reactome Pathways 2024	1.0	null
GSE86507,GSE86509_0_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hereditary ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.515
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30777
Pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.285
Septofimbrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57693
DOV13	DepMap CRISPR Gene Dependency	1.0	2.11267
Leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.944
CCNO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0188
Mediodorsal nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.33585
Stiff-Person syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.678
Huntington's Disease_CNS - Brain (MMHCC)_GSE857	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.842839
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
labeled	GeneRIF Biological Term Annotations	1.0	null
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.920904
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fascicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.097
MRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63443
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30196
ml3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.716
Sodium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.055
LTB4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75568
adult	GeneRIF Biological Term Annotations	1.0	null
ASCL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.4591
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.844126
SNU-C1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.88778
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.863988
neurotransmitter transport	GO Biological Process Annotations 2015	1.0	null
GSE225901_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
perinatal lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59419
Subcommissural organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
periglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.328994
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.44579
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QY-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
axon part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.18081
Anterior cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.016
medial mammillary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39023
HCC44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38122
Supraoptic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.691
Spinothalamic tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.234
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.50921
H2BK5ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Neural tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.535
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
hsa-miR-4799-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.12346
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
horizontal nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01694
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single organism signaling	GO Biological Process Annotations 2015	1.0	null
GSE42805,GSE42811_2_v_3_cocaine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.101
centromedian nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46857
Restless legs syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.56
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.009
mantle zone of Dg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02195
basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.955565
CMK86	CCLE Cell Line Gene CNV Profiles	-1.0	-2.2459
ZNF510	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71408
COX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29694
Globus pallidus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.403
RERF-GC-1B	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ChIP_MYC_19079543	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Specific developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.531
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
examined	GeneRIF Biological Term Annotations	1.0	null
Medial vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.807
Developmental Disabilities	CTD Gene-Disease Associations	1.0	1.17695
Inhibitory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.518
either	GeneRIF Biological Term Annotations	1.0	null
synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.142906
Cervical dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central amygdaloid nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32644
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.155
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Tanycyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.623
MAP2K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16679
ZBED4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	126.197
organic anion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF4EBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94687
TMSB4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88702
chemical synaptic transmission	GO Biological Process Annotations 2023	1.0	null
Cytoplasmic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.022
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
GADD45GIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35177
SNU449	DepMap CRISPR Gene Dependency	1.0	3.00684
axon terminus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Atrophy	CTD Gene-Disease Associations	1.0	1.33081
monocarboxylic acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3715
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
axon terminus	GO Cellular Component Annotations 2015	1.0	null
SUZ12-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Ventral striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.035
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29992
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Midbrain central gray	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.532
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.94
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lewy neurite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.637
Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CG-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
CAL-54	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.533
REST	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV3-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
m9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.716
ML-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.423
outer plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.718292
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Glial cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.501
proton transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
Postsynaptic specialization	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.585
Nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.361
PMC9950457-mmc3.xlsx-GRHL2_overexpression_DOWN-gene_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
CEP41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.75812
abnormal craniofacial morphology	MPO Gene-Phenotype Associations	1.0	null
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01838
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.906251
Postcentral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.664
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.9915
Major island of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41728
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.871666
DOLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31791
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02864
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32644
coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.383509
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18511
Presynaptic cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.525
YWHAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4804
septal nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31753
hsa-miR-1252	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ARSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0095
ChIP_H3K27me3_18600261_mouseWholeBrain	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Taurine dioxygenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.563
RNF166	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10858
clathrin-coated vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
N6AMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50084
PMC5137279__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Embryonic neural stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.553
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.90787
Cul4A-RING E3 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.938
IGSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9006
bcl11b_18199763_brain_lof_mouse_gpl1261_gds3178	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.051093
Parafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18905
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3305
dendrite terminus	GO Cellular Component Annotations 2015	1.0	null
Spike	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.513
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bam protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.643
mediodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.43103
Cul4-RING E3 ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.933
Neurofilament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.814
Sympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.013
Kidney Chromophobe_KICH_TCGA-KN-8419-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Corneal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
Dorsum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.869
IRF1	ENCODE Transcription Factor Targets	1.0	null
NEUROD2-26341353-CORTEX-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.455
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.55
Growth cone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.619
S1PR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66414
KMRC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855912
clathrin-sculpted gamma-aminobutyric acid transport vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE149903_5_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VIGABATRIN	DGIdb Drug Targets 2026	1.0	17.644
NCIH1930	CCLE Cell Line Gene Expression Profiles	1.0	2.6549
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.15864
Lateral septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36669
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.67356
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.90777
Arsenic	CTD Gene-Chemical Interactions	1.0	null
F bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.23
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.25245
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Inferior vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.288
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.98194
Subpallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.827
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4343-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
body of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.64955
Lung adenocarcinoma_LUAD_TCGA-55-8206-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inward rectifier potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.991
CPSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95285
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
Narcolepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.947
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE176008_4_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ODAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86476
TRMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.93359
NCIH1092	CCLE Cell Line Gene Expression Profiles	1.0	1.84895
SALL4-22934838-CD34+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC8816717-mmc2.xlsx-TgCRND8_P113-Unnamed_2_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.585
Olfactory placode	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.524
SAP130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74503
Ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.474
MYBL2-22936984-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Cornu ammonis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.862
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SNARE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.753
CELSR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90182
Psychomotor Disorders	CTD Gene-Disease Associations	1.0	1.15458
Precerebellar system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
Medial group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58493
Plasma membrane bounded cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.121
Neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14629
Citalopram	CTD Gene-Chemical Interactions	1.0	null
LCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28264
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37104
vglut	GeneRIF Biological Term Annotations	1.0	null
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE81803,GSE81912_3_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140937,GSE140938_0_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU1033	DepMap CRISPR Gene Dependency	1.0	3.55295
no spontaneous movement	MGI Mouse Phenotype Associations 2023	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.35536
Infundibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.85
hsa-miR-4762-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
PMC10279693-41389_2023_477_MOESM2_ESM.xlsx-N_MYC-WDR5-DMSO-overlap_peaks_a-Unnamed_15_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autism	DisGeNET Gene-Disease Associations	1.0	null
GSE145915_0_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.914
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.833
ZBTB46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11342
coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.62945
TTC709	DepMap CRISPR Gene Dependency	1.0	2.32759
cytoplasmic part	LOCATE Curated Protein Localization Annotations	1.0	null
neonatal lethality	MPO Gene-Phenotype Associations	1.0	null
Serine C-palmitoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.064
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.209
NCI-H1048	COSMIC Cell Line Gene Mutation Profiles	1.0	null
gamma-aminobutyric acid import	GO Biological Process Annotations 2025	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Skin Cutaneous Melanoma_SKCM_TCGA-HR-A2OG-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
horizontal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.826104
PMC5384880__F4	PFOCR Pathway Figure Associations 2023	1.0	null
Growth Disorders	CTD Gene-Disease Associations	1.0	1.23106
glycine transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.845492
WT1	ChEA Transcription Factor Targets	1.0	null
hsa-miR-92a	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
Subarachnoid space	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.357
Choreatic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.252
ZNF141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.99133
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.29514
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.77259
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fluoxetine	CTD Gene-Chemical Interactions	1.0	null
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.45537
GSE162892_4_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
Fourth ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.961
Hinge joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DBT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73106
Stratum lucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.041
Parahippocampal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
PMC6986441__F5	PFOCR Pathway Figure Associations 2023	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1588	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47413
pons	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.423436
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.4423
spike	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.383637
nucleus lentiformis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283899
Regio oralis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.858
Cystitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
Medium spiny neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.262
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_3Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.41471
PDGFRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81725
Variable age at onset electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
Presynapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.34
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.999045
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217139
synaptic vesicle membrane	GO Cellular Component Annotations 2023	1.0	null
Anterior horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.014
Stratum granulosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112714_2_v_3_ctnnb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
clathrin-coated vesicle membrane	GO Cellular Component Annotations 2023	1.0	null
RAD21_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-367	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.052
SNU738	CCLE Cell Line Gene CNV Profiles	1.0	1.3865
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.70761
biological regulation	GO Biological Process Annotations 2015	1.0	null
CTAGE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42332
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.269
cytoplasmic membrane-bounded vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
Cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.087
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Movement disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.014
ZNF266	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70568
chemical synaptic transmission	GO Biological Process Annotations 2025	1.0	null
GSE162892_4_v_2_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-762	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.60036
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3316-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Infundibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.769
Absence epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.901
Neuron projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
RIMS1	Pathway Commons Protein-Protein Interactions	1.0	null
Central lateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.67338
rostral putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.952414
RNF2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
respiratory failure	MGI Mouse Phenotype Associations 2023	1.0	null
LYL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Sprout	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28504
Olfactory tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.737
GSE234289_4_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SP in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.979543
abnormal adipose tissue morphology	MPO Gene-Phenotype Associations	1.0	null
CA14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99036
carboxylic acid transport	GO Biological Process Annotations 2025	1.0	null
SOX2-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.315783
Ganglion cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.862
Mediodorsal nucleus of the thalamus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.05838
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.711
Embryonic brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.622
gamma-aminobutyric acid transport	GO Biological Process Annotations 2025	1.0	null
H4K20me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
basal ganglia disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.632777
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20186
GSE178312_0_v_1_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
entire	GeneRIF Biological Term Annotations	1.0	null
synaptic vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.1751
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.283
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	81.169
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4BB-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Alcoholism	HuGE Navigator Gene-Phenotype Associations	1.0	null
ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.086974
MYC	ChEA Transcription Factor Targets	1.0	null
GSE162590_1_v_0_gsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AFF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51668
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.3593
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864649
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26931
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52191
Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Episodic ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
Liver hepatocellular carcinoma_LIHC_TCGA-RG-A7D4-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gamma-motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.42
NCIH2004RT	DepMap CRISPR Gene Dependency	1.0	3.54723
GSE180200,GSE180201_5_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.269521
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ADAM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40635
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4063835-epi-9-760-s02.xls-MI_vs_NU-SYMBOL_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
nrf1_22586274_liver_lof_mouse_gpl4134_gse35124	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.002413
Basal forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.539
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.02708
ARAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21914
Trigeminal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.891
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
Perineuronal net	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.938
Presynaptic active zone cytoplasmic component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.496
Infralimbic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.924
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.957831
Down Syndrome_CNS - Brain - Cerebellum (MMHCC)_GSE1611	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.39997
STK17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86404
GSE149903_3_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Epilepsy	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
IGLON5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44853
hsa-miR-1200	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
hsa-miR-518e	TargetScan Predicted Conserved microRNA Targets	1.0	0.127531
SLC20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23619
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20909
PMC12180985-BLOODA_ADV-2024-014495-mmc1.pdf-12-IRX3_IRX3	Rummagene Transcription Factor Associations 2026	1.0	null
Lateral geniculate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.992
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.876206
NTMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97162
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
SERPINF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33778
HEBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31482
Neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.483
Collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.437
Neostriatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.31
PMC10807933-NIHMS1954791-supplement-4.xlsx-Bag6_KD_proteomics-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Forelimb muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.765
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.84172
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.863177
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE110178_4_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
muscle phenotype	MPO Gene-Phenotype Associations	1.0	null
glycine transport	GO Biological Process Annotations 2023	1.0	null
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12443
MHHNB11	CCLE Cell Line Gene Expression Profiles	1.0	1.56387
PMC5524348-pone.0181667.s005.xlsx-Inflammation-MINT_SPEN	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1074
abnormal synaptic transmission	MPO Gene-Phenotype Associations	1.0	null
tentacle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.345188
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.235
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17669
Pervasive developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.231
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65451
hESC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.35
RFX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C-fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.614
gamma-aminobutyric acid transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
hsa-miR-25	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
Confusion	CTD Gene-Disease Associations	1.0	1.04721
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78307
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_1_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
KLF4-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.24272
hsa-miR-197	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Paranode region of axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.545
Endoplasmic reticulum palmitoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.064
Posterior amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.148
Phobic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.23
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNF2-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_8584_OE_Sorl1_SRP261088	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.5881
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.83604
bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.081303
DAUDI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH596	CCLE Cell Line Gene Expression Profiles	-1.0	-1.96754
signaling	GO Biological Process Annotations 2015	1.0	null
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053532
T-bar	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.628
NUDT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32856
GSE152432_3_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
EWS-FLI1-20517297-SK-N-MC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.297
Glutamatergic neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967567
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC5495965__F2	PFOCR Pathway Figure Associations 2023	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.894698
no abnormal phenotype detected	MPO Gene-Phenotype Associations	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
TMEM175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92331
abnormal posture	MPO Gene-Phenotype Associations	1.0	null
PKCA_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
mammillary part of THyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44552
Basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.867
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25804
GATA1	ChEA Transcription Factor Targets	1.0	null
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4538	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
RNF2	ChEA Transcription Factor Targets	1.0	null
LRRC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09783
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal inhibitory postsynaptic currents	MPO Gene-Phenotype Associations	1.0	null
avian pallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.621428
autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.698715
pc-12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.36526
hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.490619
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ID4_KO_GDS4178_620_mouse_Splenic B cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
PMC10279693-41389_2023_477_MOESM2_ESM.xlsx-N_MYC-WDR5-DMSO-overlap_peaks_a-Unnamed_14_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Duchenne muscular dystrophy (DMD)_Extraocular muscle_GSE1008	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.55792
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.07628
mRNA_SALL4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4276
Oligodendrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.182
ChIP_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13052
PAFAH1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79393
Tenia tecta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.273
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.973005
flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06649
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE7958	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.80592
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
18691415-Table5d	GeneSigDB Published Gene Signatures	1.0	null
ZBTB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48334
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
Central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.56
Superior cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.583
GABA receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.245
CRNKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81045
Forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.227
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Separation anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.0512
Thorny excrescence	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.243
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34581
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4498	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	114.081
cleft palate	MGI Mouse Phenotype Associations 2023	1.0	null
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.77776
cytoplasmic membrane-bounded vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.886551
GPR176	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64395
Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic vesicle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.367388
RIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1365
NMS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.899
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.80445
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11999
CORL24	CCLE Cell Line Gene Expression Profiles	1.0	1.97056
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0065
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.957283
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TM-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.045
Inferior temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.83258
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neuron spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.544411
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.46766
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39183
FHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83137
mushroom body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25457
outer SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19542
Agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.37
Learning disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
hPSC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.642
CTCF_SK-N-SH_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.205
Intercostal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.702
Tail	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.203
synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.79111
neuron projection	GO Cellular Component Annotations 2015	1.0	null
subpallial septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6801
ZBTB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65514
NCIH460	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08664
dorsolateral	GeneRIF Biological Term Annotations	1.0	null
fascia dentata	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.381755
RRM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13684
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z3-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
clathrin-sculpted vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65082
intermediate stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14183
ZNF609	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52911
deutocerebrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.940066
Nerve trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
glomerular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.5228
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A3-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
carboxylic acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Zona incerta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.489
Brain Edema	CTD Gene-Disease Associations	1.0	1.05721
CCSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75212
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.594
mantle zone of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14183
Mueller cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.213
H4K20me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane-bounded vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
KLF4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PHF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63966
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.206248
Claustrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.808
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4747-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46513
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
proton transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Amino acid transporter, transmembrane	InterPro Predicted Protein Domain Annotations	1.0	null
Intracellular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.624
para-abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14002
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
LIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8098
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.503824
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
Serotonin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.675
Cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.204
Hyperalgesia	DisGeNET Gene-Phenotype Associations	1.0	null
gamma-aminobutyric acid import	GO Biological Process Annotations 2023	1.0	null
Median eminence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.918
ZNF502	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71715
duchenne muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.180367
SPI1	ENCODE Transcription Factor Targets	1.0	null
abnormal embryogenesis/ development	MPO Gene-Phenotype Associations	1.0	null
RGS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27163
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55832
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ratio	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Disease Models, Animal	HuGE Navigator Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.039
MKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03541
Fragile X syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.078
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19G-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar purkinje cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.748753
Cone cell pedicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.478
neutral L-amino acid transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
complete perinatal lethality	MPO Gene-Phenotype Associations	1.0	null
KON	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
HYCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49202
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-RREB1_targets-target_gene_RREB1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.468
Striatonigral neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.059
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Paraventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.137
hsa-miR-3622b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAP3K6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65961
Specific phobia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
Fleck corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Neuronal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.93
Raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.129
POLR2A	ENCODE Transcription Factor Targets	1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.51189
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
B800-820 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.528
detected	GeneRIF Biological Term Annotations	1.0	null
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.72529
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00915
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02657
RERFLCAI	CCLE Cell Line Gene CNV Profiles	-1.0	-2.22949
SNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08996
muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055613
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.896321
amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.633549
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19Q-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lead acetate	CTD Gene-Chemical Interactions	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.07
NCI-H2009	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE144481,GSE144483_0_v_3_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
P-19 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.667
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.56123
Distal arthrogryposis type 2A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.642
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17243
RERFLCSQ1	DepMap CRISPR Gene Dependency	1.0	3.8291
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51932
people	GeneRIF Biological Term Annotations	1.0	null
HCC202	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58431
MKN7	CCLE Cell Line Gene CNV Profiles	1.0	1.41798
clathrin-coated vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
STAT3-19079543-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
SGSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88706
periventricular stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09203
Cholinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.82
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0104
Substantia innominata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.068
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07861
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.15687
SUZ12-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13705
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Leydig cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.036
ANKRD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83032
H3K9me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Neurofibrillary tangle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.151
CBX2	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4901-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
c1195	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
Cerebral ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.609
voltage-gated sodium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.893
Lateral entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.666
GSE199606_3_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.752
Nucleus lentiformis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.382
Perturb_15805_KO_Atf4_SRP350242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.1898
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27083
Distal axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.097
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ventral posterior nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
CADM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79059
Cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.179
PMC7870953-41540_2021_169_MOESM9_ESM.xlsx-SALL2_targets-target_gene_SALL2	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.952914
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KCNQ4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18732
COS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.397
SIRT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92685
autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.726929
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5748
Hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.466
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE218580_1_v_4_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
T-tubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.168
SUZ12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5928-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
STX1A	Pathway Commons Protein-Protein Interactions	1.0	null
Medulla oblongata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.202
CTCF-26484167-CHIP-SEQ-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.837
Retrocerebral complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
Nucleus preopticus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.112
nci-h295 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.200418
Anterior olfactory nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.515
ECGI10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67082
Ventral tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20089
lateral portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07402
CDX2-20551321-CACO-2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE42805,GSE42811_1_v_0_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9926
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.85861
organelle part	GO Cellular Component Annotations 2015	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELK3_ELK3	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73256
Bed nuclei of the stria terminalis, posterior division, principal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21226
amino acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE86507,GSE86509_7_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.723
lateral septal nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81319
Nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.316
neurohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.244232
abnormal survival	MPO Gene-Phenotype Associations	1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30657
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Calyx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.264
developmental process	GO Biological Process Annotations 2015	1.0	null
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.84552
compound eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294581
dendritic spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.499042
Subventricular zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.684
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Supplementary_Table_12_Genes_prioritisation_combining_FUMA_MAGMA_Hi-C_MAGMA_and_TWAS_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
asymmetric synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.546472
PHLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8616
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42036
Tentacle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.685
Attention deficit hyperactivity disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.106
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.934
PK8	DepMap CRISPR Gene Dependency	1.0	4.25962
JVM3	DepMap CRISPR Gene Dependency	1.0	2.62312
GSE210770_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.48814
TSPYL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5839
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.884928
Trigeminal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.931
Purkinje layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.887
IKZF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68904
Transport of inorganic cations/anions and amino acids/oligopeptides	Reactome Pathways 2024	1.0	null
Spinal root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuron projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.276
pallidohypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.947306
oliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.430695
UBXN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17196
Brain Diseases	CTD Gene-Disease Associations	1.0	1.41586
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01215
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERBB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2685
KLF4-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
amino acid transport	GO Biological Process Annotations 2023	1.0	null
CRYGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59063
Edema	CTD Gene-Disease Associations	1.0	1.06225
Brain Lower Grade Glioma_LGG_TCGA-DB-5281-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYBL2	ChEA Transcription Factor Targets	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
Dendritic filopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.238
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.991594
vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.516891
Pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1492
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.1016
CREBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5563
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.74426
Cheek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.105
ASH2L	ChEA Transcription Factor Targets	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AMBRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73803
CBX8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LYL1	ChEA Transcription Factor Targets	1.0	null
Tremor	CTD Gene-Disease Associations	1.0	1.03456
hsa-miR-1228	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
LAPTM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40728
PHC1-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Craniofacial Abnormalities	CTD Gene-Disease Associations	1.0	1.01814
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039539
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Asperger syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
ChIP_KLF4_19030024	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
single-organism localization	GO Biological Process Annotations 2015	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70438
GABA-A receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.203
Acute Myeloid Leukemia_LAML_TCGA-AB-3002-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.158
STK35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31411
ZNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56121
Endomembrane system	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.554
Medial dorsal nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
PHC1-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Pontine nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.887
Inhibitory neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.3006
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Dystroglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.136
GSE88819_3_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73378
ZFP64	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50001
medial longitudinal fasciculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.540188
Transmission across Chemical Synapses	Reactome Pathways 2014	1.0	null
Alcohol dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.536
abnormal inhibitory postsynaptic potential	MGI Mouse Phenotype Associations 2023	1.0	null
PMC7339600__F5	PFOCR Pathway Figure Associations 2023	1.0	null
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00168
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.0504
CTCF-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTBP2	ENCODE Transcription Factor Targets	1.0	null
abnormal nerve fiber response	MPO Gene-Phenotype Associations	1.0	null
superficial stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05144
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4790-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.402523
Peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.211
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.865
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.870232
BCPAP	CCLE Cell Line Gene CNV Profiles	1.0	1.62518
Psychoses, Substance-Induced	CTD Gene-Disease Associations	1.0	1.02933
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8785327__F4	PFOCR Pathway Figure Associations 2024	1.0	null
TMEM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28275
GSE157635_1_v_0_trem2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.844672
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.660611
CGRP receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.953
PCGF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87188
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10889
Dendritic branch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.207
Axonal spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.697
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05962
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO775	CCLE Cell Line Gene Expression Profiles	1.0	1.61494
Inner plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.742
MAZ	ENCODE Transcription Factor Targets	1.0	null
SERINC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01383
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perikaryon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.622
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.7847
ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.555956
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29945
Early myoclonic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.785
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
their	GeneRIF Biological Term Annotations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5KW-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPRED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90627
SMARCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66486
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90091
RAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24311
SLC-mediated transmembrane transport	Reactome Pathways 2014	1.0	null
Plasma membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.335
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00847
ChIP_H3K9me3_19884255_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A695-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28723
Larval brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.015
GSE199606_2_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05322
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.97966
SP8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.6313
LRRC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45431
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040459
embryogenesis phenotype	MPO Gene-Phenotype Associations	1.0	null
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.29
CNIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79693
CLEC11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86553
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38768
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Cerebral white matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.097
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059008
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.64738
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
Dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.913
STK24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53897
culture medium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.500398
substantia innominata/basal nucleus, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15818
Dopaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.301
Bergmanns glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.064
CDC42BPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81017
estradiol_rattus norvegicus_gpl85_gds2311	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.647
VAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7818
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174498,GSE174500_3_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Scolopidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.081
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.78616
HMV-II	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
GSE180185_4_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
hac cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.19292
fibre tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.457987
Autonomic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.368
striatal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.477367
IGF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12623
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
other source	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.614974
cell communication	GO Biological Process Annotations 2015	1.0	null
omphalocele	MPO Gene-Phenotype Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MJ-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hair	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.185
GSE88819_3_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Axon hillock	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.103
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.835853
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14525
Secondary motor area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0682
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7483
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.727
Oligodendroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.179
Recurrent axon collateral	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.212
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11119
Toxic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.692
Ionotropic glutamate receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.657
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955868
Tail muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.173
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.4097
ARFGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18218
neuron projection	GO Cellular Component Annotations 2023	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spinal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.553
Striatal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.026
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Microglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.111
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58085
synapse	GO Cellular Component Annotations 2015	1.0	null
EPHA4_knockout_226_GSE34430	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.05191
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142430_3_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SP-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65082
JAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16874
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26325
Olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.409
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.23306
clathrin-coated endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.776
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8755441-mmc3.xlsx-IRF7-Up-ezh2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
KS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08283
EZH2	ENCODE Transcription Factor Targets	1.0	null
Eye Abnormalities	CTD Gene-Disease Associations	1.0	1.26144
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
Perisynaptic space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.393
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91828
Synaptic vesicle, recycling pool	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.368
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.17
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
varicosity	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.451631
purkinje layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.242363
Amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.163
Temporal lobe epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.405
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24822
neurotransmitter	GeneRIF Biological Term Annotations	1.0	null
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73995
NCIH69	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63452
L-amino acid transport	GO Biological Process Annotations 2023	1.0	null
GSE157555,GSE157556_3_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.492
GSE110440_2_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31999
NG2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.875
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ERG_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.222
SW1417	CCLE Cell Line Gene CNV Profiles	1.0	1.81342
Neurosecretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.239
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3874
Cystitis	DisGeNET Gene-Disease Associations	1.0	null
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30541
gamma-aminobutyric acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
reticular nucleus of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.901526
IOMMLEE	CCLE Cell Line Gene Expression Profiles	1.0	1.43731
PAX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68869
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.37342
neurotransmitter secretion	GO Biological Process Annotations 2015	1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.856743
Gilles de la Tourette syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.43
GCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86714
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ependymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.663
Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Perturb_5100_KO_Zmym2_SRP161512	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.1565
Chloride channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.795
EED-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neutral amino acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.621
parietal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.784804
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.04347
NCIH650	DepMap CRISPR Gene Dependency	1.0	8.17841
clathrin-sculpted gamma-aminobutyric acid transport vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.671
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSDMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02334
Liver hepatocellular carcinoma_LIHC_TCGA-K7-AAU7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dendrite	GO Cellular Component Annotations 2015	1.0	null
PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PH-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049184
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
striatonigral neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.82736
Ventral globus pallidus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.254
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.57858
single-organism transport	GO Biological Process Annotations 2015	1.0	null
DDX59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35442
HAGH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81742
GSE152432_1_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.21
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0325
Alcohol use disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.463
YIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6571
neutral amino acid transport	GO Biological Process Annotations 2025	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A55W-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF9_Deficiency_GDS2703_647_mouse_Jejuna - intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Outer plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.912
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19658189-TableS4	GeneSigDB Published Gene Signatures	1.0	null
posterior lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.195145
Glutaminase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.598
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77323
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_13_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
glycine transport	GO Biological Process Annotations 2025	1.0	null
YBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55276
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	121.315
Ommatidium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
core part of DTg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95247
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50618
secondary active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
P53-22387025-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE166169_0_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pulvinar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.152
Pseudopodium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.578
Striate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.309
perinatal lethality	MPO Gene-Phenotype Associations	1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045073
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
symmetric synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.974198
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07656
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CFTR_Deficiency_GDS1843_192_mouse_Lungs - Animals examined at 6 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
WT1-20215353-NEPHRON-PROGENITOR-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NOMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35034
carboxylic acid transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
Sympathetic chain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.031
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
Giant axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.759
HDDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84623
superficial stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05262
Rostral migratory stream	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.235
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.957831
KLF4	ChEA Transcription Factor Targets	1.0	null
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
CTV1DM	DepMap CRISPR Gene Dependency	1.0	3.093
Anterior commissure	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.02
PMC8755441-mmc3.xlsx-IRF7-Up-JARID2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.09506
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.012
Hypothermia	CTD Gene-Disease Associations	1.0	1.23648
Medial temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.903
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Granular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.118
NDRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8666
Childhood electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.778
NUDT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68578
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958254
YD8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.99451
ZNF658	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62414
CTDSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39836
HCC1569	CCLE Cell Line Gene CNV Profiles	1.0	1.97555
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral septal nucleus, intermedio-intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61789
H2AC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25071
Presynaptic cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.521
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.972182
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ERI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.61342
HCC1419	CCLE Cell Line Gene CNV Profiles	1.0	1.36804
MICOS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90259
intracellular part	GO Cellular Component Annotations 2015	1.0	null
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23916
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLDIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10398
SUZ12	ChEA Transcription Factor Targets	1.0	null
Glutamatergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.838
Syp1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.678
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04478
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
synaptic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.951142
cell pole	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
organic cation transport	GO Biological Process Annotations 2025	1.0	null
culture	GeneRIF Biological Term Annotations	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Varicosity	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.154
Brain disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Rabies	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.653
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.47631
CHAGO-K-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3383-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6506-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
WM1799	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45896
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H4C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79487
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79743
Medial geniculate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.507
abnormal secondary palate development	MPO Gene-Phenotype Associations	1.0	null
inferior vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.829872
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
GSE136622_2_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterus-vascular associated smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	1.16823
KIAA2026	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89814
laterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28426
Excitatory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.134
clathrin-coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.457208
MTRFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65947
Hairy cell leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.617
layer 2 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07811
Autism spectrum disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.231
l45	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inflammatory Pain	DisGeNET Gene-Phenotype Associations	1.0	null
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.286
Articulation disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
GLRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24258
163 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.678
Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.25
diagonal part of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65356
cullin-RING ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.743
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SUZ12-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
subjects	GeneRIF Biological Term Annotations	1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03388
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Larva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.634
Chromosomal duplication syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.718
PMC9578714-elife-81083-supp2.xlsx-AA_Transporters-Gene_Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.7872
failure of palatal shelf elevation	MGI Mouse Phenotype Associations 2023	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40798
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lateral septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36036
Suprachiasmatic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.938
Drug dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
Brain Lower Grade Glioma_LGG_TCGA-DU-7292-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dystrophin-associated glycoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.27
external segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.8694
Proboscis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.127
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8724844-bt-30-1-98-supple2.xlsx-GO_BP-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
8MGBA	CCLE Cell Line Gene Expression Profiles	-1.0	-2.64191
NCI-H322M	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
PLIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57754
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5EQ-01A-21R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Diagonal band	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.34
Ventral nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.635
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Communication disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.364
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23027
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.888754
TCF12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.231
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4326-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CEP170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04892
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.90067
Perturb_2236_KO_Malat1_SRP193997	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.58176
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AURKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28113
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4327
CP66-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder-plasmacytoid dendritic cell	Tabula Sapiens Gene-Cell Associations	1.0	5.08522
SP4	ENCODE Transcription Factor Targets	1.0	null
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48285
TLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72953
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.676
Endopeduncular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.121
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPTSSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3408
beta-alanine transport	GO Biological Process Annotations 2025	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.31874
SORBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87988
Cleft Palate	CTD Gene-Disease Associations	1.0	1.04721
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IF-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Interneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.323
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12251
GSE183413_0_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPINDOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79979
TM31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4255
Neural Tube Defects	CTD Gene-Disease Associations	1.0	1.32074
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF668	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85367
gamma-aminobutyric acid:proton symporter activity	GO Molecular Function Annotations 2025	1.0	null
Dendrite terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.481
striatum_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55009
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864649
bone marrow stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.202625
PMC3255547-supp_007401_DMM007401TableS6.xls-EWS-FLI1_signatures-Unnamed_3_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
NDUFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75053
postsynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.174361
neurotransmitter loading into synaptic vesicle	GO Biological Process Annotations 2023	1.0	null
PMC8803621-mmc6.xlsx-Sup_Fig5A_genes_list-Genes_with_following_MEF2_motifs_around_their_TSS_CTAWWWATA_RSRFC4_Q2_MEF2_Q6_01_MEF2_03_MEF2_02_RSRFC4_Q2_from_GSEA_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
monoatomic ion transport	GO Biological Process Annotations 2023	1.0	null
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OSGEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07692
CMK115	CCLE Cell Line Gene CNV Profiles	-1.0	-2.10814
DNAJB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62685
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A657-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GDPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.66328
16715129-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
Puberty, Precocious	CTD Gene-Disease Associations	1.0	1.13211
A-VN-1203-2004(H5N1)_Day2-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.91012
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.510728
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24689
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.64607
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Dopaminergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.484
Perturb_13737_KO_Tbet_SRP063567	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.24438
postsynaptic density	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.302168
thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.561644
Neuron spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.542
CHD1	ENCODE Transcription Factor Targets	1.0	null
neuropil	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.941785
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05144
Perturb_1997_KO_Arid1b_SRP344792	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.44859
Integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.29
Rosette	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.495
Mesocorticolimbic dopaminergic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.95
Hamstring muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.929
cell-cell signaling	GO Biological Process Annotations 2015	1.0	null
Perturb_15083_KD_Nsd1_SRP354984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.8822
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38679
ventral anterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07718
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal voluntary movement	MPO Gene-Phenotype Associations	1.0	null
superficial stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15017
abnormal motor capabilities/coordination/movement	MPO Gene-Phenotype Associations	1.0	null
CCNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7535
Seizures	CTD Gene-Disease Associations	1.0	1.44382
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02571
Exocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.15
GTF3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99215
ENDOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1668
Pilocarpine	CTD Gene-Chemical Interactions	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
PMC5384880__F8	PFOCR Pathway Figure Associations 2023	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.858314
ChIP_RNF2_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
neutral L-amino acid transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48561
esophagus	GTEx Tissue Gene Expression Profiles	-1.0	-0.924126
Frontotemporal dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.31
Prostate adenocarcinoma_PRAD_TCGA-EJ-8469-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
clathrin-coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9578714-elife-81083-supp2.xlsx-AA_Transporters-Common_Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0588
Median nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.157
HT55	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5669
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.8574
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.8861
Weight Gain	CTD Gene-Disease Associations	1.0	1.15593
Status epilepticus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.109
hsa-miR-944	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
TRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51952
hsa-miR-4773	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.2518
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.906
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.935704
adrenocortical carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.187069
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MRPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63853
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHU029	DepMap CRISPR Gene Dependency	1.0	4.13702
BACH1	ENCODE Transcription Factor Targets	1.0	null
COS-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.373
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebral cortical neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.327164
Diagonal band nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09203
pericellular basket	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.25438
vigabatrin	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
Amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.72
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.678
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78511
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10X-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neurohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.777
Uterine horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.023
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11242
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52173
Antennal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.278
PHC1	ChEA Transcription Factor Targets	1.0	null
fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.910946
r3 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79533
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23684
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.067054
MKN7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.11202
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreatic alpha cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.286381
Hepatitis	CTD Gene-Disease Associations	1.0	1.16799
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE249714_0_v_1_anxa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.14889
antibodies	GeneRIF Biological Term Annotations	1.0	null
Dendrite cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.762
Dermatome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
RNF26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21284
Cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.384
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06117
Brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.914
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.18337
Glucose Intolerance	CTD Gene-Disease Associations	1.0	1.07163
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dendrite	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
normal	GeneRIF Biological Term Annotations	1.0	null
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75256
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Neocortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.548
Inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.428
Myelencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.195
MTMR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62397
Superior temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.294
deficits	GeneRIF Biological Term Annotations	1.0	null
coated vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-4697-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CBX2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stratum lucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.718292
mRNA_NANOG_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Phrenic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.177
dendrite terminus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Medial septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.337
bone marrow stromal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.507457
KCND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49919
ZRANB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39771
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33528
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
M07E	CCLE Cell Line Gene Expression Profiles	-1.0	-2.09985
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.02522
P2URK562	DepMap CRISPR Gene Dependency	1.0	2.31904
Cell cortex region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.52
orofacial cleft	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.241895
GSE147366_3_v_2_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
bipolar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.52556
Mild cognitive impairment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.39
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.09381
PCI38	DepMap CRISPR Gene Dependency	1.0	5.68008
hsa-miR-570	TargetScan Predicted Conserved microRNA Targets	1.0	0.078844
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Presynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.11
Dentate gyrus mossy fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.43
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.31965
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01863
hsa-miR-4764-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
AIRE_KO_GDS2274_246_mouse_Medullary thymic epithelial cells (with high CD80 expression)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-4533	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Rostral ventrolateral medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.112
BMI1-23680149-NPCS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.516
STAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.538
PF382	CCLE Cell Line Gene Expression Profiles	1.0	1.90698
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044703
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.832804
voltage-gated potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.792
Multiple sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.525
cytoplasmic vesicle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
MKN45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebral gray matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.164502
RAD21	ENCODE Transcription Factor Targets	1.0	null
Cation channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.593
SORT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2903
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_15_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Transmembrane transport of small molecules	Reactome Pathways 2014	1.0	null
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.75074
PRKCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49644
PMC7339600__F5	PFOCR Pathway Figure Associations 2024	1.0	null
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.855114
abnormal palate development	MPO Gene-Phenotype Associations	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAL1	ChEA Transcription Factor Targets	1.0	null
Perturb_662_KD_lncRNA_177417_SRP093784	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.36624
Prefrontal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.577
Granule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.456
Retrograde endocannabinoid signaling	KEGG Pathways 2026	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7838-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypoglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
NCIH889	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47419
respiratory system phenotype	MPO Gene-Phenotype Associations	1.0	null
GEM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39144
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.05927
ChIP_SUZ12_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
Freeman-Sheldon syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
MARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10855
TCP1_02_194	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.0
REST	ChEA Transcription Factor Targets	1.0	null
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.73373
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
RPS27L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84338
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2722
mammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44552
Neuronal System	Reactome Pathways 2014	1.0	null
ASPC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GET4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27982
NCIH2227	CCLE Cell Line Gene Expression Profiles	1.0	3.408
Down syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.68
Mood Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
INSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55511
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
X-linked dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.993
cation transport	GO Biological Process Annotations 2015	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5753
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
Arcuate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.908
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TM-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.978
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.750185
NLRX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41186
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81A-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.159
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.249257
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_7day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.71012
GSE112174_5_v_7_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01372
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.531879
GSE145915_3_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE86507,GSE86509_4_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04735
Rhomboid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.054
Rectum adenocarcinoma_READ_TCGA-AG-3731-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP6D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72398
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KATNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06161
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.06067
ChIP_SOX2_19030024	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.201
Perturb_10440_KO_Gsx2_SRP295638	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.82751
adrenocortical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.181185
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27347
Paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16598
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.827839
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MESP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13206
P300-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SUDS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31329
Ataxia	CTD Gene-Disease Associations	1.0	1.54572
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25376
RNF2-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.948
Lm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.008
CCDC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15518
MRPL51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93358
GFUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30239
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPFIA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42905
infancy electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.577327
Primary pulmonary hypoplasia_Lung Tissue_GSE1363	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.66941
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.983555
Frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.797
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prefrontal	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07342
abnormal umbilical cord morphology	MPO Gene-Phenotype Associations	1.0	null
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KIRREL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95846
Dermal dendritic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.325
Corpus albicans	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.834
glycine transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Multiple system atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
GATA2	ChEA Transcription Factor Targets	1.0	null
Syndromic X-linked intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
Gluteal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.717
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
complete neonatal lethality	MPO Gene-Phenotype Associations	1.0	null
Lateral mammillary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.363
cytoplasmic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
JUNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29946
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.882162
CAMLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83653
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dendrite	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Intralaminar nuclei of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28783
Prostate adenocarcinoma_PRAD_TCGA-EJ-5494-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATPase inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.767
synaptic cleft	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.368919
GSE151829,GSE151831_3_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.87295
PMC8563805-41598_2021_858_MOESM2_ESM.xlsx-Supplementary_Info_8-Gene_List_8_The_list_of_human_orthologs_of_the_downregulated_fly_DEGs_identified_from_PARIS_C571A_mutant_vs_PARIS_wild_type_comparison_ZNF746	Rummagene Transcription Factor Associations 2026	1.0	null
Synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.462
synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.189539
Accessory olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.581
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16004
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.32113
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
Pars intermedia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
symporter activity	GO Molecular Function Annotations 2015	1.0	null
Nucleus preopticus medialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.783
YIPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2497
Anterior lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.284
Postsynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.297
CFAP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65209
AGPAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39445
NBPF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75641
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.240276
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7603555-8790531.f1.docx-0-AHDC1_AHDC1	Rummagene Transcription Factor Associations 2026	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.90459
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.48412
Spinal trigeminal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.954
DNMBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55665
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31137
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Septal area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.507
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058607
mrnas	GeneRIF Biological Term Annotations	1.0	null
Cerebral subcortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
Pyramidal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.118
Dorsal nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.303
endocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.142822
JAR	DepMap CRISPR Gene Dependency	1.0	2.78038
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	5.6975
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_13920_KD_HNRNPK_SRP312616	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11242
cell projection	GO Cellular Component Annotations 2015	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
Vascular Malformations	CTD Gene-Disease Associations	1.0	1.08442
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.28782
cerebellar vermis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25802
nci-h295r cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.479312
GSE147943_5_v_1_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GABA receptor signaling	WikiPathways Pathways 2024	1.0	null
Presynapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.3065
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09935
153br	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.267
striatal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59468
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
middle cerebral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21883
hsa-miR-3622a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CJ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9793
amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.299601
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
anion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8105-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GATA1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC8283158-mmc2.xlsx-TCF4_ChIP-symbol_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IMPDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84758
OCI-AML5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC5495965__F2	PFOCR Pathway Figure Associations 2024	1.0	null
RERFGC1B	CCLE Cell Line Gene CNV Profiles	1.0	2.33566
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7839
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.31843
Brain Lower Grade Glioma_LGG_TCGA-HT-7476-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRK-NU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Presynaptic periactive zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.593
abnormal adipose tissue distribution	MGI Mouse Phenotype Associations 2023	1.0	null
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.086469
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM86B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43507
synapse part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SCAR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.806
Transmembrane transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.445
Transport vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
vesicular	GeneRIF Biological Term Annotations	1.0	null
cytoskeletal calyx	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.181823
BT474	CCLE Cell Line Gene CNV Profiles	-1.0	-2.84268
Vomeronasal organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.095
Secondary motor area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31339
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.951673
organic anion transport	GO Biological Process Annotations 2015	1.0	null
JARID2-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.962114
Calcitonin family receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.05
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.872676
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27494
EP300	ENCODE Transcription Factor Targets	1.0	null
Sensorimotor area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.124
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53252
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Fetal Resorption	CTD Gene-Disease Associations	1.0	1.10388
Nucleus accumbens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.441
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.246098
SQSTM1_OE_GDS2653_651_human_IMR-32 neuroblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Palmitoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.125
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
GATA2-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-3652	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
SNAP25	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5444
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.68753
MESP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01087
CTCFL	ENCODE Transcription Factor Targets	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.89958
C2BBE1	CCLE Cell Line Gene CNV Profiles	1.0	1.64332
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2525
motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.808551
Cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.221
coated vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
l-amino acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
pars reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.726918
Macroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.498
PMC5823716-onc2017356x6.xlsx-350POS_noreps_txt-Supplementary_Table_4_ESC_SNAI1_FLK1hi_UP_Human_orthologs_of_top_350_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE144481,GSE144483_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lateral habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69371
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.34343
Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.999482
Proximal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.728
TPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62728
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EED-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Integrator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.017
CTDSPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11292
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
REST_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-32	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
C1orf21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66507
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Carotid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.577327
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.384
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Outer nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.054
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.557897
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.850721
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6571-01A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Synaptic vesicle, resting pool	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.769
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19015
USP45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59588
BL674 (PAF1)	NURSA Protein Complexes	1.0	null
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
GSE205291,GSE205292_1_v_3_drd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN28	DepMap CRISPR Gene Dependency	1.0	2.08787
Perturb_3452_KO_Plp1_SRP073495	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.35967
TMEM230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39134
SPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48728
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.369628
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09444
pRb_Deficiency_GDS3176_605_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08804
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.73
MCAS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06644
Medial amygdaloid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.404
Medial septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87933
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.969274
neuron part	GO Cellular Component Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0824
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.11571
Perturb_5565_KO_Tal1_SRP119777	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
cholera	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.58433
NCIH1650	CCLE Cell Line Gene CNV Profiles	1.0	1.32769
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47241
SLC66A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92467
HS839T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58753
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Juxtaglomerular apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.538
Postsynaptic density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.545
GSE199606_2_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal body wall morphology	MPO Gene-Phenotype Associations	1.0	null
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tailbud stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.918
s1391	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.549
DDX60L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02813
myelencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.585625
NCIH1436	CCLE Cell Line Gene Expression Profiles	1.0	2.40871
Vagina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.403
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USP17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78783
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1636
Coated vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.03973
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S9-ZNF384_SpecDMCs-Unnamed_3_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.838028
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.8693
r7 part of the posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51157
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KDM2B-26808549-CHIP-SEQ-SIL-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE223008_11_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.71358
EGR1	ENCODE Transcription Factor Targets	1.0	null
dendrite	GO Cellular Component Annotations 2025	1.0	null
FGFR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5289
Synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.164
NDUFS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5249
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
KMS27	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48595
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4670_KO_Pten_SRP154291	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Memory Disorders	CTD Gene-Disease Associations	1.0	1.93613
Perineuronal net	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.824
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
monovalent inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
ELAVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97737
CYB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57733
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DU4475	DepMap CRISPR Gene Dependency	1.0	2.40591
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48312
Habenular trigone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.328
RAB6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3418
Glycine	HMDB Metabolites of Enzymes	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39383
Brain Lower Grade Glioma_LGG_TCGA-DU-6400-01A-12R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adrenal gland cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.185763
pancreatic islet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.146886
Horizontal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.972
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.342
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-363	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
layer 1 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32411
SUZ12	ENCODE Transcription Factor Targets	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_1day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.61566
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intermediate filament cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.978
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.788
Exocytic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Caudate putamen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.949
Transport of small molecules	Reactome Pathways 2024	1.0	null
GSE148066,GSE157787_9_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.871
SNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47158
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vglut2	GeneRIF Biological Term Annotations	1.0	null
Ventrobasal complex of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
CAL29	CCLE Cell Line Gene CNV Profiles	1.0	1.8007
hunched posture	MPO Gene-Phenotype Associations	1.0	null
VMRCLCD	DepMap CRISPR Gene Dependency	1.0	2.30502
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.17425
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7945
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
voltage-gated calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.564
Synaptic ribbon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.069
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045071
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
umbilical hernia	MPO Gene-Phenotype Associations	1.0	null
cytoplasmic vesicle part	GO Cellular Component Annotations 2015	1.0	null
NCI-H2066	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.1429
GPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62564
Exocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.983
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7251
Neuro-2a cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.01
A10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
BCL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58
STRBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08574
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.912929
mantle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.255567
pyramidal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.44404
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GT-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS79	CCLE Cell Line Gene Expression Profiles	1.0	1.80036
Hypoglossal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.247
H4K20me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.861
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
postcentral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.988032
Hereditary neuropathy with liability to pressure palsies	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
regulation of neurotransmitter levels	GO Biological Process Annotations 2015	1.0	null
Rabies CVS-11_7day-Brain_22116324_GSE30577	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.95499
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040556
Intrinsic component of periplasmic side of cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.643
terminals	GeneRIF Biological Term Annotations	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-6546-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L-type voltage-gated calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.019
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anorexia nervosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pituicyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.320227
PMC5384880__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Peripheral ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.556
Neuromuscular junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.778
inferior olivary complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.276495
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Circumventricular organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.93
Neural plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.14
Middle frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.669
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.9201
GABPA	ENCODE Transcription Factor Targets	1.0	null
MGAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36072
Cytoskeleton of presynaptic active zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.492
WHSC1	ENCODE Transcription Factor Targets	1.0	null
Transfer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.619
C1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4462
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.859852
Interneuron_Prefrontal cortex_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE193588_1_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Psp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
Abdominal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.31
PM20D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15428
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05432
NCIH209	CCLE Cell Line Gene Expression Profiles	1.0	1.34969
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.553
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81319
synapse part	GO Cellular Component Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4773428-ncomms10751-s5.xlsx-S_Table_4-Supplementary_Data_4_RUNX1_responsive_genes_in_the_presence_and_absence_of_estradiol_E2_in_MCF7_cells_FC_1_5_p_0_05_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
monocarboxylic acid transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21226
GSE210885_5_v_6_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052447
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.716
ZNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5353
Spine apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.126
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
diagonal domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02534
RAB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50917
GATA1-19941827-MEL-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Methionine	CTD Gene-Chemical Interactions	1.0	null
gamma-aminobutyric acid:proton symporter activity	GO Molecular Function Annotations 2015	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06509
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7465
Lateral posterior nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49659
striate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.567227
Cleft palate-lateral synechia syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vision Disorders	CTD Gene-Disease Associations	1.0	1.10769
RAD21_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epilepsy syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.243645
throughout	GeneRIF Biological Term Annotations	1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hyperkinesis	CTD Gene-Disease Associations	1.0	1.24591
SUZ12-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.863713
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neurula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.942
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lambdoid septal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26983
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whereas	GeneRIF Biological Term Annotations	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14525
Nervous System Malformations	CTD Gene-Disease Associations	1.0	1.37874
SARS-BatSRBD_Day4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.79996
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perisynaptic extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.939
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mitral cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.952
Omphalocele	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.816
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.947
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27577
superficial stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4416
Weight Loss	CTD Gene-Disease Associations	1.0	1.5123
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.85
Enteric muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
Juvenile myoclonic epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
Habenula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.557
TYKNU	DepMap CRISPR Gene Dependency	1.0	3.29978
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
motor cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.315861
ZNF143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53936
cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Lattice corneal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.607
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24473
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.809817
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Neuron projection terminus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Basal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.955
Chromosomal deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
Opioid abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
PLAGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0719
Fibrosis	CTD Gene-Disease Associations	1.0	1.44954
adipose tissue phenotype	MPO Gene-Phenotype Associations	1.0	null
anteroventral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41075
nm94	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
neuron projection terminus	GO Cellular Component Annotations 2015	1.0	null
Main axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.478
NCIH2122	DepMap CRISPR Gene Dependency	1.0	3.22601
Acn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
ZNF41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99376
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Multiple synapse bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.581
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
cleft palate	MPO Gene-Phenotype Associations	1.0	null
Catecholaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.549
r1 part of dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57693
GPX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4158
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.644
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46583
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40838
Neural stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.864
Major depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.147
TAMALIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55921
Idiopathic generalized epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.528
MGRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5081
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.872633
monoatomic ion transport	GO Biological Process Annotations 2025	1.0	null
Neurotransmitter release cycle	Reactome Pathways 2024	1.0	null
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRL_Deficiency_GDS2936_630_mouse_Retinas - 10 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043712
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.932
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864649
WDR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93115
cation-transporting ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.937
S bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.252
PSMC3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04533
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.366381
Aorta thoracica smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebral artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.169396
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.56
CDR2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43382
Breast Cancer_Mammary Gland Tissue_GSE3744	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.05234
Somatodendritic compartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.102
Somatoform disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sciatic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.359292
Epithalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69561
RAD21_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-92b	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal nervous system physiology	MPO Gene-Phenotype Associations	1.0	null
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.489311
Fascia dentata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.879
Mycolate outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.06
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.25601
Astroglial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.488
PMC10335698-pone.0285806.s007.xlsx-DMKN-shRNA_KD_Vs_ShSrc-Unnamed_9_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Adrenal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.431
Dendritic lamellar body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.788
parallel fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.264215
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31821
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.977838
Adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.664
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21811
GLI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63514
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71S-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
glutamatergic	GeneRIF Biological Term Annotations	1.0	null
pheochromocytoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.189267
SOX3-22085726-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bed nuclei of the stria terminalis, posterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24458
POLR2A_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
subthalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08338
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03165
Cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.98
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864649
Hippocampal pyramidal layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.118
Medial cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.775
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Amino acid and oligopeptide SLC transporters	Reactome Pathways 2014	1.0	null
Cranium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.514
cerebellar cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.947809
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.827254
Ion channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.654
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.942656
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.938412
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.12088
no abnormal phenotype detected	MGI Mouse Phenotype Associations 2023	1.0	null
Abnormalities, Multiple	CTD Gene-Disease Associations	1.0	1.11536
Perturb_16637_KO_Drd2m_SRP377988	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.45265
Bed nuclei of the stria terminalis, anterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05262
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5137279__F4	PFOCR Pathway Figure Associations 2023	1.0	null
Nucleus preopticus medianus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.937
gamma-aminobutyric acid:proton antiporter activity	GO Molecular Function Annotations 2025	1.0	null
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	138.835
Gemmule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.633
MLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53728
Hyperplasia	CTD Gene-Disease Associations	1.0	1.40787
anterodorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09109
failure of palatal shelf elevation	MPO Gene-Phenotype Associations	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055279
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.1724
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amino acid transmembrane transport	GO Biological Process Annotations 2015	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.936
NCIH1792	CCLE Cell Line Gene Expression Profiles	-1.0	-2.01596
Entorhinal area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00021
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
Midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.78
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955868
Posterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06109
H3K27me3_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Interanteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45304
LYL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-11A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4754	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
Potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.668
intralaminar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77376
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72515
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.70711
cellular process	GO Biological Process Annotations 2015	1.0	null
Chromaffin cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.213
motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.326281
Olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.706
CREB1	ChEA Transcription Factor Targets	1.0	null
PRAME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09836
Peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.256
Parahippocampal region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.125
ARPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
H4K20me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus of the diagonal band, left, vertical division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18806
MMAC	DepMap CRISPR Gene Dependency	1.0	3.08215
EGR3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	92.2977
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC26A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65616
496100639_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03323
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.402523
Climbing fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.127
Neuronal cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.321
synaptic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Dorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82789
SLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38048
inhibitory synapse	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.83836
GSE223008_7_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Fibre tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.022
Synaptic cleft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.614
medulla oblongata	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.589234
central lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2367
LXF289	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3594
RAD21_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JAGN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69426
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00765
abnormal nervous system electrophysiology	MPO Gene-Phenotype Associations	1.0	null
GSE225141,GSE225143_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RING1B-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCIH510	DepMap CRISPR Gene Dependency	1.0	2.74296
GSE228992_0_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neurotransmitter secretion	GO Biological Process Annotations 2025	1.0	null
carboxylic acid transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.558
Bed nucleus of stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.921
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.04383
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16328
RAD21_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.6958
clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.556
LOXIMVI	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62597
abnormal craniofacial development	MPO Gene-Phenotype Associations	1.0	null
ZBED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86544
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.3827
GSE151782_2_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
synaptic vesicle cycle	GO Biological Process Annotations 2023	1.0	null
CTSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52113
Neurotransmitter Release Cycle	Reactome Pathways 2014	1.0	null
Folic Acid	CTD Gene-Chemical Interactions	1.0	null
Nucleus preopticus periventricularis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.17
CAL-148	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SELENOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8657
FLI1-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Sudden infant death syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
SMC3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Body wall muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.958
Agranular insular cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.458
putamen, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.62926
Nuclear replisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.149
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Withdrawal disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
carboxylic acid transport	GO Biological Process Annotations 2015	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
SKMEL24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83445
H4K20me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Dopaminergic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.712
PMC4823830-ncomms11171-s4.xlsx-high_in_shRNA_TCF1-GeneSymbol_HNF1A	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1385	CCLE Cell Line Gene Expression Profiles	1.0	1.49474
globus pallidus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.394953
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.477367
Bed nuclei of the stria terminalis, posterior division, interfascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25423
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Semaphorin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.673
CDX2-20551321-CACO-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
lateral vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.501182
Heterochromatin domain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.139
sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.194038
ARH-77	COSMIC Cell Line Gene Mutation Profiles	1.0	null
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.19445
Cholera	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.629
Dendritic spine head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.246
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.32438
KLHDC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75304
nervous system phenotype	MPO Gene-Phenotype Associations	1.0	null
dravet syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.595233
Thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.512
CPLX1	Pathway Commons Protein-Protein Interactions	1.0	null
Dendritic tree	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.079
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.11214
hsa-miR-4469	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.297
cone cell pedicle	GO Cellular Component Annotations 2015	1.0	null
GSE128333_3_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01292
Tegmentum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.675
superficial stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06949
ZNF157	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98424
Uvula (IX)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00048
Psoriasis vulgaris_Skin tissue_GSE14905	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.29697
STAT3-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Visual cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.537
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1915
Vibrissa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.557
GSE111660_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-A493-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17594
Magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10958
intermediate stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59206
CCHCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19446
Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.312232
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cytosolic region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.039
MOGS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30721
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
Sexual Dysfunctions, Psychological	CTD Gene-Disease Associations	1.0	1.09857
POU3F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45436
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.61476
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Lateral vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.461
Limbic encephalitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
SLAC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.036
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32013
MTF2	ChEA Transcription Factor Targets	1.0	null
Speech disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.195
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.216
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
signal release from synapse	GO Biological Process Annotations 2023	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.671
ChIP_SUZ12_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cleft Palate	DisGeNET Gene-Disease Associations	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Lateral dorsal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.197
Transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.722
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MONOMAC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9041
Nausea	CTD Gene-Disease Associations	1.0	1.19312
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044698
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZHX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04641
RHOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83925
Area postrema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.424
Retrosplenial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.009
Mature stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28631
GSE86507,GSE86509_4_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5556-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.510992
YAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08865
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE132948,GSE132949_4_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.3228
Subesophageal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.159
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.307033
Periglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.952
Morbid obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.346
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21811
Brain Lower Grade Glioma_LGG_TCGA-DB-5279-01A-03R-2347-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ISCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36115
FEZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14924
HELQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14634
Dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.074
Anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.383
anterior horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.258243
abnormal inhibitory postsynaptic potential	MPO Gene-Phenotype Associations	1.0	null
Rubrospinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.283
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.63405
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8810962__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5311-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G3BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3421
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.898292
gamma-aminobutyric acid:proton antiporter activity	GO Molecular Function Annotations 2023	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Pitcher	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.727
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045996
CEP55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82587
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25V-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50152
mantle zone of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61016
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6964
Lateral septal nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47813
lateral hypothalamic area, anterior region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.995422
abnormal neurotransmitter level	MPO Gene-Phenotype Associations	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.97747
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61099
Li-Fraumeni syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
horizontal	GeneRIF Biological Term Annotations	1.0	null
amino acid:monoatomic cation antiporter activity	GO Molecular Function Annotations 2023	1.0	null
HS766T	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
Electric organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
Mo-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
ZNF846	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5185
intermedioposterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39376
schizophrenia	GeneRIF Biological Term Annotations	1.0	null
clathrin-sculpted gamma-aminobutyric acid transport vesicle	GO Cellular Component Annotations 2025	1.0	null
RABAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03396
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16991
zfpm2_19411579_heart_lof_mouse_gpl1261_gds3659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.745032
Sensillum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.995
Inner nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.588
Cerebellar Purkinje cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.277
Cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.248
Cerebellar disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.492
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Acidosis	CTD Gene-Disease Associations	1.0	1.23106
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
glycine transport	GO Biological Process Annotations 2015	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14864_KD_ZRSR2_SRP341591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.27843
adolescence-adult electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
Perturb_8939_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.368
synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.75724
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.41938
Liver hepatocellular carcinoma_LIHC_TCGA-2V-A95S-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Axon initial segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.433
Cranial nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.997
Hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.107
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.206
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tsA-201 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.507
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.925367
EIF3J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7752
visual cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.511384
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4890-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAIP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71823
TRIM28	ChEA Transcription Factor Targets	1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3986
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Subthalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.975
cation:amino acid symporter activity	GO Molecular Function Annotations 2015	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058339
Medial longitudinal fasciculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.516
synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.744574
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19013
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08957
mantle zone of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59468
GATA1-19941827-MEL-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RANBP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57626
ESRRB-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.231
PMC6986441__F5	PFOCR Pathway Figure Associations 2024	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Synaptic vesicle pathway	WikiPathways Pathways 2024	1.0	null
membrane-enclosed lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.120943
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
exocytic vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.860311
cytoplasmic vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.97013
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.30101
GSE141624_3_v_0_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Inferior olivary complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.617
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062272
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.628
MERO95	DepMap CRISPR Gene Dependency	1.0	2.18173
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24707
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BL4874 (FBXO11)	NURSA Protein Complexes	1.0	null
Nucleus reuniens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
Cob	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
organelle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.126862
abnormal digestive system morphology	MPO Gene-Phenotype Associations	1.0	null
vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.941
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gap junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.655
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Axon terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.17
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
axons	GeneRIF Biological Term Annotations	1.0	null
PU.1-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Hypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.856
Neuropil	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.454
external plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283191
TMEM120B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15158
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cytoplasmic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuronal cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.250751
GSTA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3277
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.95113
NCI-H209	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.59584
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
D341MED	CCLE Cell Line Gene Expression Profiles	1.0	1.44367
Plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.944
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nicotine dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A26S-11A-12R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFO-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.91828
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
organic substance transport	GO Biological Process Annotations 2015	1.0	null
subthalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62155
clathrin-sculpted vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Ascidian	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.861
GABAergic neuron_Ventral posterior hypothalamus (VPH)_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.936097
EFM192A	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48528
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (ventral) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27173
inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.505537
EGR1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0582
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
Alexander Disease_CNS - Brain - Olfactory Bulb (MMHCC)_GSE977	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.55021
THBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17429
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.921199
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
GSE198683_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EWSR1	ChEA Transcription Factor Targets	1.0	null
TBX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68199
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12/HEB-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
KLKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21075
ML-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.154
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rhinencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.847
Puncta adhaerentia	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.075
GATA2-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06243
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.784156
TMUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98075
substantia innominata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09529
CAMK2N2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98679
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78431
glycine transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Protocerebrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.444
secondary active monocarboxylate transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
FAM171A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13654
GSE86507,GSE86509_3_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal locomotor behavior	MPO Gene-Phenotype Associations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91102
Biceps femoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.08158
PU1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CA9-22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Astrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.482
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Glycine encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
NUGC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cerebral gray matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.581
Bipolar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.082
ARHGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45699
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01188
cochlear nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22023
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5951
Brain myelin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.636
excitatory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.765438
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
SMARCA4	ChEA Transcription Factor Targets	1.0	null
Cerebral cortical neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.558
KDM2B-26808549-CHIP-SEQ-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53299
signal release	GO Biological Process Annotations 2015	1.0	null
Hyperekplexia 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
Glomerular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.029
Juxtaglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.6
Pain disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
EBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14117
ChIP_PHC1_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me1_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Amblyopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
PCBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00989
cell tip	GO Cellular Component Annotations 2015	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
decreased neurotransmitter release	MPO Gene-Phenotype Associations	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864649
Postsynaptic cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.659
TE6	DepMap CRISPR Gene Dependency	1.0	2.79114
ion transport	GO Biological Process Annotations 2015	1.0	null
Eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.203
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A820-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mural cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.863
Presynaptic actin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.983
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	211.433
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.097594
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06725
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65451
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11102563-41531_2024_715_MOESM1_ESM.pdf-150-GATA3-AS1_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.27779
Periventricular nucleus of hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.422
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.25653
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANKS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9295
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_4944_KO_Rybp/Yaf2/Prc1_SRP247114	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
digestive/alimentary phenotype	MPO Gene-Phenotype Associations	1.0	null
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39657
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.039
Limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.187
16951165-Table1a	GeneSigDB Published Gene Signatures	1.0	null
prefrontal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.262986
Dentate granule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.024
Neuronal dense core vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.743
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TOLEDO	CCLE Cell Line Gene Expression Profiles	1.0	1.58709
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.39366
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CA-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.29317
BHLHE22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37979
hsa-miR-3974	TargetScan Predicted Conserved microRNA Targets	1.0	0.115091
SOX11-22085726-ESNS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
septodiagonal transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14183
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ARHGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37029
Encephalitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
Cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.627
DTX3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84199
Coma	CTD Gene-Disease Associations	1.0	1.34926
primary atelectasis	MPO Gene-Phenotype Associations	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65082
Fascia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.818
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glutamate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.607
Myelin sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.636
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.00857
solute:proton symporter activity	GO Molecular Function Annotations 2015	1.0	null
Epilepsy	DisGeNET Gene-Disease Associations	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050817
Vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.683
G protein-coupled receptor dimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.509
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.980443
isoforms	GeneRIF Biological Term Annotations	1.0	null
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.491
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRYZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20985
Heart Diseases	CTD Gene-Disease Associations	1.0	1.01587
LRFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24042
blood	GTEx Tissue Gene Expression Profiles	1.0	0.928611
Stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.626
Lyf-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Medial habenular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.063
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.769027
PMC6097700-pgen.1007515.s007.xlsx-S1_Table-S1_Table_SATB2_NuRD_gene-set_list_SATB2	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3B	ChEA Transcription Factor Targets	1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC30A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94244
Anxiety	DisGeNET Gene-Disease Associations	1.0	null
integral component of synaptic vesicle membrane	SynGO Synaptic Gene Annotations	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.169
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06644
Syndromic X-linked intellectual disability Lubs type	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
Germ cell cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.416
SFRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34031
ZNF385A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74204
C1orf174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60358
Parallel fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.992
Orofacial cleft	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.637
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0406
upper (rostral) rhombic lip_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1134
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vgat	GeneRIF Biological Term Annotations	1.0	null
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MM485	DepMap CRISPR Gene Dependency	1.0	6.68261
PAM complex, Tim23 associated import motor	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.728
Dentate gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.556
lateral septal nucleus, intermedio-ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60504
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
omphalocele	MGI Mouse Phenotype Associations 2023	1.0	null
mortality/aging	MPO Gene-Phenotype Associations	1.0	null
GSE149096_4_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GABA synthesis, release, reuptake and degradation	Reactome Pathways 2024	1.0	null
periventricular stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05405
Calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.534
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11415
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.3311
neuron projection terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.30927
DNMT3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80589
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE133763_0_v_1_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21728
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21055
PMC9578714-elife-81083-supp2.xlsx-AA_Transporters-Ensembl_ID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Tubular Necrosis, Acute	CTD Gene-Disease Associations	1.0	1.1122
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHMP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28634
neurotransmitter transport	GO Biological Process Annotations 2023	1.0	null
Hip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.087
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36472
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.60036
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.969351
OVMIU	DepMap CRISPR Gene Dependency	1.0	2.7895
Synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.397
hiPSC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.44
mRNA_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Transport vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
KDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0425
MYC	ENCODE Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.19507
CYB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66717
PLEKHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89513
GSE235596_0_v_1_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sima	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.045
GSE86507,GSE86509_3_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Apical dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.484
transport	GO Biological Process Annotations 2015	1.0	null
Cell body fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.075
EZH2	ChEA Transcription Factor Targets	1.0	null
Integral component of postsynaptic density membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.564
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32848
ac2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.813
lateral septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.50704
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27347
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.977486
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.17771
EGR1	ChEA Transcription Factor Targets	1.0	null
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.58851
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7393-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
establishment of localization in cell	GO Biological Process Annotations 2015	1.0	null
establishment of localization	GO Biological Process Annotations 2015	1.0	null
inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064145
Middle temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.789
TRIM45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33965
amino acid transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
CARD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75335
NOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25159
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	133.023
PMC8755441-mmc3.xlsx-IRF7-Up-SUZ12_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
Pallidum, ventral region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01364
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27339
ARF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72964
KE39	CCLE Cell Line Gene Expression Profiles	-1.0	-1.96346
Corticotropic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.5
H3K9me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
body wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.14342
INPP5F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93482
KDM2B-26808549-CHIP-SEQ-DND41-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.751
Glycine	DrugBank Drug Targets	1.0	null
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.831508
EWS-FLI1-20517297-SK-N-MC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79507
biological_process	GO Biological Process Annotations 2015	1.0	null
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.256234
blood-brain barrier	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.322
outer SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.826322
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.231
lung	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.926655
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.916
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.67569
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC-19079543-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Olfactory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.535
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-01A-21R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Large_Intestine-intestinal enteroendocrine cell	Tabula Sapiens Gene-Cell Associations	1.0	0.84181
Photoreceptor distal connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.774
CDX2	ChEA Transcription Factor Targets	1.0	null
Lateral ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.444
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ANKEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35823
Thymus-thymocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.84181
UQCRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13407
substantia nigra	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.325335
ZKSCAN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52683
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KAT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94019
transporter	GeneRIF Biological Term Annotations	1.0	null
Flexor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.245
dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.935016
TLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3739
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.22596
synaptic vesicle cycle	GO Biological Process Annotations 2025	1.0	null
HSPA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32633
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05541
alpha-motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.45
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3986
Pilus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.266
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15592
Principal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.723
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
Corpus cardiacum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.943
Preeclampsia_Placenta_GSE4707	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.51824
Pallidum, medial region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4195
ZCCHC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16834
neuron projection	GO Cellular Component Annotations 2025	1.0	null
Mesolimbic dopaminergic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
Substance abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.736
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE189653,GSE203344_2_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TENM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21929
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49477
Adrenomedullin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.714
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC2	CCLE Cell Line Gene CNV Profiles	1.0	1.55446
hsa-miR-875-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
Dendritic spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.538
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.0397
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20875
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_665_KO_Myc_SRP093784	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.1493
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.441
Presynaptic density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.165
smarcc2_00000000_e12dot5_embryonic_cortex_lof_mouse_gpl6887_gse45629	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.81098
Trigeminal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.926
hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.69052
LONRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31427
GSE81803,GSE81912_3_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsomedial preoptic area, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04066
FAM181B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24489
transporter activity	GO Molecular Function Annotations 2015	1.0	null
Synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.986
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04261
inhibitory synapse	GO Cellular Component Annotations 2015	1.0	null
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day14-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
trans-synaptic protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.303
ZNF181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85926
Perturb_4210_KO_Dmrt5_SRP127681	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.72717
Acute Myeloid Leukemia_LAML_TCGA-AB-2970-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05144
olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.866842
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Nerve ring	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.018
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98522
CAKI1	DepMap CRISPR Gene Dependency	1.0	2.00434
Arachnoid mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.861
Kidney Chromophobe_KICH_TCGA-KL-8338-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49004
HCC-827	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KDM2B-26808549-CHIP-SEQ-HPB-ALL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Regio parietalis capitis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.689
Perturb_8476_KO_CTNNB1_SRP137216	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.763
arcuate nucleus of medulla, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53123
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24844
Subiculum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.132
HS766T	CCLE Cell Line Gene CNV Profiles	1.0	2.08687
Piriform area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12933
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amino acid:proton symporter activity	GO Molecular Function Annotations 2025	1.0	null
organelle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Corpus allatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.657
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055662
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Distal arthrogryposis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
Parietal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.578
BC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SP9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.849
abnormal adipose tissue distribution	MPO Gene-Phenotype Associations	1.0	null
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.88036
Vagus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.614
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
viaat	GeneRIF Biological Term Annotations	1.0	null
abnormal respiratory system physiology	MPO Gene-Phenotype Associations	1.0	null
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampal pyramidal layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.44404
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.841571
Locus ceruleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.314
ALDOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53639
olfactory tubercle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1305
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SH4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99465
SW1271	COSMIC Cell Line Gene CNV Profiles	1.0	2.64759
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.36998
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-8489-01A-31R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8940_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.1803
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71835
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08125
H3K36me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal nervous system electrophysiology	MGI Mouse Phenotype Associations 2023	1.0	null
GSE180200,GSE180201_15_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111981
C14orf132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60747
hsa-miR-4712-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Pancreatic Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
RCCFG2	DepMap CRISPR Gene Dependency	1.0	2.16056
STAT3-19079543-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FXYD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98208
WERIRB1	DepMap CRISPR Gene Dependency	1.0	3.12487
GSE140936,GSE140938_0_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
KO52	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50686
Posterior hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.458
respiratory failure	MPO Gene-Phenotype Associations	1.0	null
GSE221633_3_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PRRX2_PRRX2	Rummagene Transcription Factor Associations 2026	1.0	null
pioglitazone_mus musculus_gpl2897_gse8806	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Delirium	CTD Gene-Disease Associations	1.0	1.08161
Rett syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.286
NUDT18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65701
ACAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72127
GSE114883_1_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CEBPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80217
ZNF677	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46827
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.879921
superficial stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10509
glycine:proton antiporter activity	GO Molecular Function Annotations 2023	1.0	null
Ventricular zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.757
atelectasis	MPO Gene-Phenotype Associations	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.916948
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81R-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.179
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01904
Neuron projection terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.197
ALKBH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00212
Cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.452
serotonin-activated cation-selective channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.584
ZSCAN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80728
SNAPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43787
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	2.65319
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.767
CUL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44457
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.72981
GABAergic neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.969
embryonal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.181798
Substance-Related Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02301
NFKBIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8751
Synaptic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
REM sleep behavior disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
Immature cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.941
Cleft Lip	CTD Gene-Disease Associations	1.0	1.20622
Anterodorsal preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16942
Bergmann fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.102
SKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
SOX17_OE_GDS3300_124_human_HESC (CA1 and CA2)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KM-12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23462
abnormal cns synaptic transmission	MPO Gene-Phenotype Associations	1.0	null
Intermediate filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.978
Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic alpha cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.93
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.76092
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5097-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Choroid plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.233
GATA1-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Umbilical hernia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
Timothy syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
POLR2G_02_09	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.12928
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Medial septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41497
intermediate stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32027
PMC8905236-mmc2.xlsx-Table_S10-Table_S10_Differentially_regulated_genes_in_SPI1_high_vs_low_group_in_CGGA_GBM_dataset_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
Liver Cirrhosis	CTD Gene-Disease Associations	1.0	1.04314
Filopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.094
cleft secondary palate	MGI Mouse Phenotype Associations 2023	1.0	null
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060532
SLC36A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46821
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.914
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05451
Plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.575
Neuroepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.499
Lateral habenular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.239
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.50636
cone cell pedicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.916496
muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05475
Unverricht-Lundborg syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.116436
Demyelinating disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.538
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0384
STOML1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92138
Invertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.162
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
preweaning lethality	MPO Gene-Phenotype Associations	1.0	null
GLS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15585
PEX14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0835
Postpartum depression	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
clathrin-sculpted gamma-aminobutyric acid transport vesicle	GO Cellular Component Annotations 2023	1.0	null
Childhood absence epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.895
Tritocerebrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.634
TFPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30625
Neuron_Brain_Human	CellMarker Gene-Cell Type Associations	1.0	null
clone81	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Neuroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.495
Substantia nigra	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.264
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1441
normal phenotype	MPO Gene-Phenotype Associations	1.0	null
Cerebellar mossy fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.755
AU565	CCLE Cell Line Gene CNV Profiles	1.0	1.41616
RXRA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61897
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.971426
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37071
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Bed nuclei of the stria terminalis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10603
monocarboxylic acid transport	GO Biological Process Annotations 2015	1.0	null
Lateral geniculate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.965
Olfactory glomerulus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
BMI1	ChEA Transcription Factor Targets	1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.75781
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06627
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
vagina	GTEx Tissue Gene Expression Profiles	-1.0	-1.58246
Neuroactive ligand signaling	KEGG Pathways 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4631-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CECR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9119
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08283
vertical nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60768
monocarboxylic acid transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
Plasma membrane signaling receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.327
secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.071111
Paraquat	CTD Gene-Chemical Interactions	1.0	null
Subdural space	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
RUNX1	ChEA Transcription Factor Targets	1.0	null
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
Spine synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.393
hsa-miR-1303	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A7EI-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MMP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1942
CLCN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44025
PMC8093449__F5	PFOCR Pathway Figure Associations 2024	1.0	null
ahl1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
Giant cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.148
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.714498
Internal capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.81
COR-L88	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Restless legs syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
Tic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
GPRC5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50798
Acute Myeloid Leukemia_LAML_TCGA-AB-2807-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
craniofacial phenotype	MPO Gene-Phenotype Associations	1.0	null
ESRRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38978
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.112
myositis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.089035
pontine nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.66918
GSE223008_7_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STXBP1	Pathway Commons Protein-Protein Interactions	1.0	null
Adenohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.215
CTCF-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
anion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
NMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
circulating leptin levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.61549
sodium:potassium-exchanging ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.959
localization	GO Biological Process Annotations 2015	1.0	null
THUMPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60769
major	GeneRIF Biological Term Annotations	1.0	null
COMMD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57829
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16709
CORO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73135
adrenal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.135225
Dentate gyrus HICAP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.222
YY1	ENCODE Transcription Factor Targets	1.0	null
Dendritic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.538
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.928915
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.14623
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.51087
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rootlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
somatosensory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.00152
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pars compacta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.267446
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
Aorta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
epithelial-stromal TGFBI dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.586
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.39231
Meynert's basal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.253
TRIM28-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Masseter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.774
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05608
Cerebral peduncle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.6
Neuron_Retina_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
TC32	CCLE Cell Line Gene Expression Profiles	1.0	1.43297
AGBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25004
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.983414
PCI-6A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRG1_DEPLETION_GDS2156_720_mouse_Embryos (maternally depleted)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NLGN4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90528
midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.750818
cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
decreased neurotransmitter release	MGI Mouse Phenotype Associations 2023	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14849
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29N-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV644	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31999
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.76275
hsa-miR-4742-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.047969
Optic cup	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.12
Lateral posterior nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.164
cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.683335
Pallidum, caudal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10071
Serotonergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.174
Leptomeninx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.133
SET2	DepMap CRISPR Gene Dependency	1.0	3.88927
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
i10	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15033
adrenal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.466498
ZFX-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Needle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.981
FRA10AC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62106
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RDH14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32214
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.85
cell tip	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
H3K27me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
synaptic vesicle neurotransmitter loading	SynGO Synaptic Gene Annotations	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
l23	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.194
NOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52558
A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_4day-MOI-10^4_None_GSE37572	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.86029
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.57803
ChIP_EED_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5691-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.792
SPOTS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.071
Diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.891
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.107
cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Embryonic stem cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.006
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.11939
CMTM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39448
L-amino acid transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89181
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.585108
solute:sodium symporter activity	GO Molecular Function Annotations 2015	1.0	null
Thoracic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.259837
GSE112860_5_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.005967
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
adult retina	HPM Cell Type and Tissue Protein Expression Profiles	1.0	1.14787
Tadpole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.275
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05661
Shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.598
SUZ12-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LMX1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46887
abnormal muscle tone	MPO Gene-Phenotype Associations	1.0	null
RNF114	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11493
CCND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4374
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37671
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053438
Eye-retinal bipolar neuron	Tabula Sapiens Gene-Cell Associations	1.0	1.49464
Cerebral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.208
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.33623
Pericellular basket	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.471
neuron projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.24812
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.56117
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
Angelman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.586
Retinal ganglion cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.772
GSE114553_0_v_1_lhx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE139427_2_v_1_ibrutinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Axon cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.099
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17615
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.859612
SMAD1-26771354-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
ChIP_H3K27me3_20682450_humanESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
icSARS CoV_36Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.41077
SARS-CoV MA15_Day1-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.60251
Dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.607
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.33917
Temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.143
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A114-11A-12R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.821746
RXRA	ENCODE Transcription Factor Targets	1.0	null
PNMA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95078
Focal epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.407
HCN channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.75
BCCIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90296
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8148
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAP1GAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76571
PSMB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07909
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	2.24738
SALL4	ChEA Transcription Factor Targets	1.0	null
GSE132948,GSE132949_2_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
antisera	GeneRIF Biological Term Annotations	1.0	null
PHPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79858
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PEER	CCLE Cell Line Gene Expression Profiles	1.0	1.75452
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.960707
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.811
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12382
l35	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.206
axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.18646
l-amino acid transport	GO Biological Process Annotations 2015	1.0	null
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
Lewy body dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
Lung adenocarcinoma_LUAD_TCGA-44-7670-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
secretion by cell	GO Biological Process Annotations 2015	1.0	null
LZTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77038
Corticospinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.482
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.2198
Ost-alpha/Ost-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.882
M040416	DepMap CRISPR Gene Dependency	1.0	2.60715
GSE199606_1_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Motor trigeminal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.641
Synaptic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.784
CTCFL_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal abdominal wall morphology	MPO Gene-Phenotype Associations	1.0	null
neurotransmitter secretion	GO Biological Process Annotations 2023	1.0	null
Varicosity	DisGeNET Gene-Disease Associations	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
Stuttering	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
muscle hypertonia	MGI Mouse Phenotype Associations 2023	1.0	null
Juxtaparanode region of axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.552
Motoneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.337
Hippocampal mossy fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.447
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parkinsonism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.59
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38044
Vascular smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.561
CTCFL_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neocortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.13235
secondary active monocarboxylate transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
abnormal palate morphology	MPO Gene-Phenotype Associations	1.0	null
ZNF136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38258
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18793
head of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.62655
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88793
Central medial thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.241
SCARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30169
WFIKKN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52593
abnormal nerve fiber response	MGI Mouse Phenotype Associations 2023	1.0	null
Inhibitory neuron_Amygdala_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4247
Pars compacta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.946
SUP-HD1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.719
ST6GALNAC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05547
Neuron projection cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.137
CTNNB1	ChEA Transcription Factor Targets	1.0	null
NMI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90426
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.088
H4C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17355
Auditory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.218
hsa-miR-4430	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
Paraventricular nucleus of hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.914
ZNF527	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55249
FADU	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4807
Hyperekplexia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.292
Preoptic area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.482
TCF3	ENCODE Transcription Factor Targets	1.0	null
clathrin-coated vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
snare complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.348725
GSE108675_2_v_1_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055432
HEL9217	DepMap CRISPR Gene Dependency	1.0	3.07961
inner plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.352969
Visceral hump	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.277
cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.183328
periventricular part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65876
NCIH1963	CCLE Cell Line Gene Expression Profiles	1.0	2.13763
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C22orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7588
Ventromedial hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.804
Vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.52
GSE142684_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REEP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96021
RL	DepMap CRISPR Gene Dependency	1.0	2.4611
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.861363
amino acid:monoatomic cation antiporter activity	GO Molecular Function Annotations 2025	1.0	null
b65	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.532
KMS26	DepMap CRISPR Gene Dependency	1.0	2.24232
Periplasmic side of cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.643
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41316
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04666
JARID2	ChEA Transcription Factor Targets	1.0	null
abnormal respiration	MPO Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Distal arthrogryposis type 2B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
bed nucleus of the stria terminalis, mediocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00382
Pineal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.943
Deutocerebrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.453
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.611
Dendritic tuft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.631
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glutamate decarboxylase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.91
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.893943
principal sensory nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.950124
rnf2_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.094508
Dravet syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.913
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRRC40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41701
Central amygdaloid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.58
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.940967
cell culture	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.61578
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.818
Substance-Related Disorders	CTD Gene-Disease Associations	1.0	1.14473
Laterodorsal thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.488
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19836
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.86558
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Medial mammillary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.819
mantle zone of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65093
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
glutamate	GeneRIF Biological Term Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.891475
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.932339
cerebral cortex	HPA Tissue Protein Expression Profiles	1.0	2.04572
Anterior hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.792
17660535-TableS4c	GeneSigDB Published Gene Signatures	1.0	null
axon initial segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.200663
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19198
Presynaptic active zone membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.758
Rod spherule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.417
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.69799
post-traumatic stress disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.964
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Syndromic intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP13A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06659
Neuron projection branch point	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.298
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62581
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24963
JMJD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43338
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Medial entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.852
GAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44483
icSARS-Cov_Day4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.6311
IGF2BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94152
H1 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.91777
Sciatic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.641
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
neutral amino acid transport	GO Biological Process Annotations 2023	1.0	null
Entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.171
Node of Ranvier	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.568
vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.243879
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal neurotransmitter secretion	MPO Gene-Phenotype Associations	1.0	null
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.78231
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881669
GSE132948,GSE132949_0_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DLG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88401
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.458241
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5456-11A-02R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amino acid transport	GO Biological Process Annotations 2025	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.71191
umbilical hernia	MGI Mouse Phenotype Associations 2023	1.0	null
striatum_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850367
Synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.83405
NCI-H2170	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Antisocial personality disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.5795
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1703
Pinealocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.833
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42298
Cerebrospinal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.357
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38421
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
DNA replication factor A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.299
KYSE270	CCLE Cell Line Gene Expression Profiles	1.0	1.69933
solute:cation symporter activity	GO Molecular Function Annotations 2015	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
acidic amino acid transport	GO Biological Process Annotations 2025	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
axon	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.588
SP1	ENCODE Transcription Factor Targets	1.0	null
PMC12297505-41598_2025_11704_MOESM4_ESM.xlsx-table_s4_veen-GSE16011_AND_TCGA-GBMLGG_NOT_Human_kinases_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
NEU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5921
Uranostaphyloschisis	DisGeNET Gene-Disease Associations	1.0	null
DDX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45373
Lateral septal nucleus, caudal (caudodorsal) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09896
GSE129241_4_v_6_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
AXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40386
Nucleus solitarius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.226
Synaptic Vesicle Pathway(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.904475
Pons	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.836
hsa-miR-148b-3p	MiRTarBase microRNA Targets	1.0	null
NKX2-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80208
G protein-coupled GABA receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.6
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052902
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87016
MYC-19079543-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
tonic-clonic seizures	MGI Mouse Phenotype Associations 2023	1.0	null
Dendritic branch point	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.298
CD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7951
Embryoid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.42
IM-95	COSMIC Cell Line Gene Mutation Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.865348
Traumatic brain injury	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.661
Coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
obsessive-compulsive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.754
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22282
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Non-alcoholic Fatty Liver Disease	CTD Gene-Disease Associations	1.0	1.26236
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72054
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADCY9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51073
calcium- and calmodulin-dependent protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.198
Autoimmune disease of central nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.551
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10641
CTNNB1-20460455-HCT116-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SLC-mediated transmembrane transport	Reactome Pathways 2024	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Attention deficit hyperactivity disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.531
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
CL14	CCLE Cell Line Gene Expression Profiles	-1.0	-2.72204
Tuberous sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
SAP30	ENCODE Transcription Factor Targets	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
ZSWIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32433
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
giant cell carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.549312
TE-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cerebellar nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.162
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.969274
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Impulse control disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
anion transport	GO Biological Process Annotations 2015	1.0	null
H3K27me3_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Generalized anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
UGT3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4249
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06554
beta-alanine transport	GO Biological Process Annotations 2023	1.0	null
MSANTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17405
WM983B	CCLE Cell Line Gene CNV Profiles	1.0	1.41798
Bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.187
GSE261563_9_v_4_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
COV362	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44825
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lateral septal nucleus, rostral (rostroventral) part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44613
MOLT13	CCLE Cell Line Gene Expression Profiles	1.0	1.68283
H4K20me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MOLM6	CCLE Cell Line Gene CNV Profiles	-1.0	-2.61759
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.338506
interneuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.78689
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4354-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventral nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.564
pallidal septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60768
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1413
DPH7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44535
primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.25877
Axolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.277
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Floor plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.398
Dendritic growth cone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.58
EZH2-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
18614019-TableS4d	GeneSigDB Published Gene Signatures	1.0	null
EVSAT	DepMap CRISPR Gene Dependency	1.0	8.28538
TDRD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16568
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53935
inhibitory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.5656
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COMTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88808
Cranial ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.941
Intrinsic component of cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.643
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adrenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.355198
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Phelan-McDermid syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.579
MYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42898
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04868
pentabromodiphenyl ether	CTD Gene-Chemical Interactions	1.0	null
Lateral dorsal nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36371
3e1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
pinealocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.347778
Entorhinal area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.236
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.920265
Site of polarized growth	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.593
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41752
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neonatal period electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27347
Perturb_14211_KO_Sp8/Sp9_SRP084329	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Central nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00323
Cerebellar granule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.751
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.502
Myelin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.577
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BL8346 (KIAA1688)	NURSA Protein Complexes	1.0	null
Perturb_8943_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.88261
hsa-miR-4453	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
zona incerta	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.847955
Cortical amygdaloid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.889
Spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.275
H357	DepMap CRISPR Gene Dependency	1.0	2.58378
rett syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.717635
brain	GTEx Tissue Gene Expression Profiles	1.0	1.72804
Dendrite terminus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
MEX3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67507
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.82197
UMC-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46208
Infancy electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22817
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4332150-msb0011-0775-sd13.xlsx-JUN-Prey_Gene_Symbol_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
Superior vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.539
SKOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93502
CMK	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99765
ACTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88016
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06689
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
LMO2	ChEA Transcription Factor Targets	1.0	null
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.774347
Laterodorsal tegmental nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.095
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCaRG_OE_GDS2426_711_human_HEK293 kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Nape	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.133
Oliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.04
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tongue muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.009
secretion	GO Biological Process Annotations 2015	1.0	null
Brain ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.396
PRSS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2806
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
gigantocellular group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.889011
AMPA glutamate receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.584
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	2.30751
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
INTS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66063
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Avian pallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.737
ZNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12538
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MGH-U3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
GSE142684_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRKAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64943
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.801
TBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53115
STAT3-24763339-IMN-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.289
DFCI024	CCLE Cell Line Gene Expression Profiles	1.0	1.46262
GSE86507,GSE86509_7_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
interanterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65428
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WASF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39964
Parastrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16942
Cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.113
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89169
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26396
Migraine	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00382
cell pole	GO Cellular Component Annotations 2015	1.0	null
Temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.269
clathrin-coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K27me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.53053
Face	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.702
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.937467
giant cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.208361
piccolo-bassoon transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.941
abnormal muscle physiology	MPO Gene-Phenotype Associations	1.0	null
CEBPB-21427703-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
gaba	GeneRIF Biological Term Annotations	1.0	null
Choline	CTD Gene-Chemical Interactions	1.0	null
Movement Disorders	CTD Gene-Disease Associations	1.0	1.38641
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12586
EZH2-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
QPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24094
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A465-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199606_3_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRDM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39232
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37311
Photoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.745
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.86278
superficial stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51022
STK38L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94178
Autoimmune disease of the nervous system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.549
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
circulating leptin levels adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.669897
DNASE1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56096
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.816904
horizontal nucleus of the diagonal band, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05078
Postsynaptic cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.558
USF2	ENCODE Transcription Factor Targets	1.0	null
Leading edge membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.239
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A149-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE224742_0_v_1_slc1a5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.14623
granule cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.937059
pancreatic beta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.176802
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.673
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.73778
TBP	ENCODE Transcription Factor Targets	1.0	null
WDR83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87241
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3953
TAF1	ENCODE Transcription Factor Targets	1.0	null
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.671
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65894
NCIH1184	CCLE Cell Line Gene Expression Profiles	1.0	2.04754
CCDC184	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3152
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.858172
pg cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.552093
EZH2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14869
Prelimbic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.157
mRNA_SOX17_20123909	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Imago	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.627
GSE110178_2_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE4619	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.48885
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.87511
Posterior cingulate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.702
Synaptic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
NCI-H1623	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tcf3_21972416_linnegflt3poscd127posly6dneg_bone_marrow_lof_mouse_gpl1261_gse27402	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.159409
Medial geniculate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.263
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	1.74886
hunched posture	MGI Mouse Phenotype Associations 2023	1.0	null
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
Clathrin adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.141
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO829	CCLE Cell Line Gene Expression Profiles	-1.0	-2.53518
Corpus striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.685
ep16	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.64
Umbilical Hernia	DisGeNET Gene-Phenotype Associations	1.0	null
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metal ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.828171
UBAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8467
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41942
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancreatic beta cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.169291
main axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.346829
LIN7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56587
lateral (parvicellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.44594
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diphtheria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.953
anovulation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.382594
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14525
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.681096
Postsynapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.815
PMC11659471-41398_2024_3203_MOESM2_ESM.xlsx-Table_SE_9-Table_SE9_Z_scores_comparing_signficant_genes_from_OUD_dataset_Seney_et_al_and_rat_models_of_heroin_and_or_LPS_injection_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61758
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Subfornical organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.475
Kidney renal papillary cell carcinoma_KIRP_TCGA-Q2-A5QZ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.75875
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
RPL7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95228
Amyloidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.196
no spontaneous movement	MPO Gene-Phenotype Associations	1.0	null
Perturb_4198_KO_Fmr1_SRP075646	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.74279
Nigrostriatal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
Posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21574
Sertoli cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Mitral cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.789
nitrogen compound transport	GO Biological Process Annotations 2015	1.0	null
Ms	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_JARID2_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior paraventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.829
Triangular nucleus of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26406
Cholinergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.535
ICC137	DepMap CRISPR Gene Dependency	1.0	2.09544
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.814
Posterior periventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
hsa-miR-4488	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98131
Stratum granulosum cerebelli	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.94738
lateral trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4416
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1413
synapse	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6762
Perturb_8478_KO_PTPN2_SRP077320	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.7264
BMI1-23680149-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
LB1047RCC	DepMap CRISPR Gene Dependency	1.0	2.21541
Glutamatergic postsynaptic density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.44
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8132
GSE151494_1_v_9_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.337
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.06612
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	47.5131
HOXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47685
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2856
ARHGDIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65534
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.554
LAMA84	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63882
MYBL2-22936984-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
anterior paraventricular nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18284
Rce	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1898
GBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48598
HCC1954	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41482
Anchored component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.501
Vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.997
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
synaptic transmission	GO Biological Process Annotations 2015	1.0	null
NCIH2009	DepMap CRISPR Gene Dependency	1.0	2.49382
OC314	DepMap CRISPR Gene Dependency	1.0	2.29073
SPPL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38771
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal extraembryonic tissue morphology	MPO Gene-Phenotype Associations	1.0	null
Ependymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.677
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064302
lethality during fetal growth through weaning	MPO Gene-Phenotype Associations	1.0	null
vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.429859
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RVH421	CCLE Cell Line Gene CNV Profiles	1.0	1.34797
Congenital Exomphalos	DisGeNET Gene-Disease Associations	1.0	null
Corpus callosum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.876
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
IGFBPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6322
EED	ChEA Transcription Factor Targets	1.0	null
Calyx of Held	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.021
Neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.345
AP-type membrane coat adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.148
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.877
clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane	GO Cellular Component Annotations 2025	1.0	null
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GATA1-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.0049
Spinal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.3
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9112
active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXO3_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
hydrogen:amino acid symporter activity	GO Molecular Function Annotations 2015	1.0	null
abnormal inhibitory postsynaptic currents	MGI Mouse Phenotype Associations 2023	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17591
Biceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.955
H3K9me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dendritic shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.297342
CTCF	ENCODE Transcription Factor Targets	1.0	null
gabaergic	GeneRIF Biological Term Annotations	1.0	null
GSE132948,GSE132949_2_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CNN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90845
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.97582
Essential tremor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36707
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Abdominal Pain	CTD Gene-Disease Associations	1.0	1.04574
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEC1B	DepMap CRISPR Gene Dependency	1.0	3.90255
Chromaffin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.111
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR3	ChEA Transcription Factor Targets	1.0	null
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2577
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0307
HCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62903
Personality disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
vglut1	GeneRIF Biological Term Annotations	1.0	null
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Huntington's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.797
signal release from synapse	GO Biological Process Annotations 2025	1.0	null
Synaptic vesicle cycle	KEGG Pathways 2026	1.0	null
PG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.169
neuron part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
G protein-coupled receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.433
lateral septal nucleus, intermedio-dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58693
Cerebellar cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.495
Uvula (IX), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02195
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.965274
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.859612
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048899
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inhibitory	GeneRIF Biological Term Annotations	1.0	null
optic lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.225395
PMC10243915-uxad037_suppl_supplementary_table_s1a.pdf-499-SPDEF_SPDEF	Rummagene Transcription Factor Associations 2026	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE132948,GSE132949_0_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17024
Adrenocortical carcinoma_ACC_TCGA-OR-A5KV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UOK101	DepMap CRISPR Gene Dependency	1.0	2.38061
Soft body part	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.613
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-h-Classification_of_camel_SON_basal_genes_-_transporters_SON	Rummagene Transcription Factor Associations 2026	1.0	null
Astrocyte projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.348
outer CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.865076
CREB1_01_195	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.69007
Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05939
Developmental and epileptic encephalopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.965
Von Economo's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
DAPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43076
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-HEB_CCRFCEM_ChIP-seq_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
neuron projection terminus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
occipital lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.417718
KYM1	DepMap CRISPR Gene Dependency	1.0	2.20318
Habenular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.328
cortex	GeneRIF Biological Term Annotations	1.0	null
P3HR1	CCLE Cell Line Gene Expression Profiles	1.0	1.38725
pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.929173
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
RING1B-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6L9-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.889
Somatodendritic compartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
corpus striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.814397
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2952-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8168-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	2.24306
H3K27me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lateral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23371
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A1A1-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219264
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA2_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.201
GSE85880,GSE85881_4_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
granule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.1142
hsa-miR-3167	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
COLO678	DepMap CRISPR Gene Dependency	1.0	2.2224
Dorsal raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.25
dendrite	GO Cellular Component Annotations 2023	1.0	null
central part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.692
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Caudate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.331
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.73339
germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.062776
SNU216	DepMap CRISPR Gene Dependency	1.0	2.13132
Mediodorsal nucleus of the thalamus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.11503
muscle hypertonia	MPO Gene-Phenotype Associations	1.0	null
SOX2-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
periventricular stratum of Dg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00382
endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.665166
Bed nuclei of the stria terminalis, posterior division, transverse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49674
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07482
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.0244
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64118
NAMALWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
excitatory	GeneRIF Biological Term Annotations	1.0	null
antennal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.432225
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44006
HCC44	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3344
PBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66666
pheochromocytoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.362273
acidic amino acid transport	GO Biological Process Annotations 2023	1.0	null
NMU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32621
HAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52291
TRIM47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21098
ACTR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02221
Dizziness	CTD Gene-Disease Associations	1.0	1.09471
KYSE140	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33718
PIPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6798
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.8075
GSE174735_2_v_0_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.079802
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasm	LOCATE Curated Protein Localization Annotations	1.0	null
Vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
protein-cysteine S-palmitoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.064
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.735971
terminal bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.08577
neurotransmitter transport	GO Biological Process Annotations 2025	1.0	null
Dura mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.473
GATA2-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
lateral subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51666
TESMIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89093
SOX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72425
Cerebral degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
FKRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59512
Posterior nuclear complex of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.512
clathrin-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.67143
VM-CUB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Epithalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.283
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.56
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29571
hsa-miR-3692	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
hsa-miR-3140-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
Tetanus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.067
Nucleus preopticus lateralis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.719
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	8.41151
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.971318
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05279
FHIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29821
Schaffer collateral - CA1 synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.838
GABAergic neuron_Central amygdala_Human	CellMarker Gene-Cell Type Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A118-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.603
NB1	DepMap CRISPR Gene Dependency	1.0	3.67582
Melancholic depression	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
Sc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.153
CORL51	CCLE Cell Line Gene Expression Profiles	1.0	2.25278
extracellular matrix part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.05343
Amyloid plaque	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.149
CTNNB1-20460455-HCT116-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Testicular cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72353
Piriform area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.14
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.184231
Intrinsic component of postsynaptic density membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.546
LRPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38537
Vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.468
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43013
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01858
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
against	GeneRIF Biological Term Annotations	1.0	null
BASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21712
RAD21_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MQ-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
Photoreceptor ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.913
Organum vasculosum laminae terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.244
organic acid transmembrane transport	GO Biological Process Annotations 2015	1.0	null
HTRA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10193
mRNA_OTX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MARCHF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1057
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34117
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881669
clathrin-coated vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Dorsal striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.176
ODF2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15979
b1647	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.869
Focal hand dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.204
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.967567
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PF-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sodium ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Insular cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.867
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Filopodium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.62
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
WT1-20215353-NEPHRON PROGENITOR-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_4492_KO_Tcf4_SRP072458	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H4K20me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4971-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
cell projection part	GO Cellular Component Annotations 2015	1.0	null
substantia innominata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0241
gamma-aminobutyric acid transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.853
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.844
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Terminal bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.092
PPARGC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64595
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.74525
Perturb_4209_KO_Dmrt3/Dmrt5_SRP127681	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.29368
RNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28894
Neonate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.543
synaptic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.923
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MC-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dicarboxylic aminoaciduria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
fibromyalgia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.411657
PMC6853299-pbio.3000476.s011.xlsx-Fig_4A-HVC_612_gene_expression_ratio_in_ZF_and_OF_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77922
Necrosis	CTD Gene-Disease Associations	1.0	1.91519
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47814
abnormal palatal shelf elevation	MPO Gene-Phenotype Associations	1.0	null
ChIP_STAT3_19079543	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Sleep disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.934
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Juvenile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.058
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.85152
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27839
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60141
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.609276
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65655
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23829
Olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.588
neonatal lethality, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
KDM2B-26808549-CHIP-SEQ-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Panic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
Lung adenocarcinoma_LUAD_TCGA-97-8177-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H1-0	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42474
OCT4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
embryonal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.208245
Perturb_15776_OE_Nmnat2_SRP360949	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.39545
Hippocampal mossy fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.11
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.202
Stellate cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.412
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.642
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dentate gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.22648
Mental Disorders	CTD Gene-Disease Associations	1.0	1.07732
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.03271
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043857
IKBIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96488
been	GeneRIF Biological Term Annotations	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE86507,GSE86509_3_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ins-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.394953
Presynaptic endocytic zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.313
A3KAW	DepMap CRISPR Gene Dependency	1.0	2.86437
internal plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.671285
organic acid transport	GO Biological Process Annotations 2015	1.0	null
increased kindling response	MGI Mouse Phenotype Associations 2023	1.0	null
LARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45171
HDGFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24286
gamma-aminobutyric acid transport	GO Biological Process Annotations 2015	1.0	null
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.3169
JARID2-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Corn silk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
PMC7064337-elife-51373-supp1.xlsx-EZH2_targets_shPHF19-List_of_2084_genes_marked_by_EZH2_ChIPseq_after_PHF19_KD_shPHF19_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KIJK	CCLE Cell Line Gene Expression Profiles	1.0	1.54883
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45986
TPCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99667
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.46648
synaptic vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
synapse part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.69522
cerebellar cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03115
Ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.683
Somatic spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.483
HCC4006	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79644
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
amino acid:proton symporter activity	GO Molecular Function Annotations 2023	1.0	null
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.466
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15592
Occipital lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.446
Flower	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.431
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.592
Neurosecretory vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.245
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21121
GSE223008_11_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RT112	DepMap CRISPR Gene Dependency	1.0	2.14225
vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.299
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49647
Cleft palate	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.658
synapse-associated extracellular matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.939
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5384880__F8	PFOCR Pathway Figure Associations 2024	1.0	null
Mediodorsal nucleus of the thalamus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.35709
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.751645
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
Distal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.307
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
cleft palate	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.301615
Frt	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.63
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.938
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.52
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE112860_0_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nuclear replication fork	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.127
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30878
Asi complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.921
RAD21_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.717
SARS-CoV MA15_Day2-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.56772
ZNF232	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31258
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Activating signal cointegrator 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.318
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44921
Ebolavirus(EBOV)_7day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.89061
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Secretory vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
PHF8	ENCODE Transcription Factor Targets	1.0	null
Asymmetric synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.625
Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
35 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.13
JHH-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1898
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.919874
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.914791
PPP1R1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10454
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57953
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.856517
Poisoning	CTD Gene-Disease Associations	1.0	1.53234
Morphine addiction	KEGG Pathways 2026	1.0	null
neurotransmitter loading into synaptic vesicle	GO Biological Process Annotations 2025	1.0	null
ventral globus pallidus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.249653
JURKAT	DepMap CRISPR Gene Dependency	1.0	3.10499
4-aminobutyrate transaminase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.357
Perirhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.538
Choroid plexus epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03349
superficial stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64087
TOE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45118
Symmetric synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.604
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055068
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.864734
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.578494
gamma-aminobutyric acid transport	GO Biological Process Annotations 2023	1.0	null
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
axon terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.29639
Perturb_6637_KO_SATB1_ERP024525	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kenyon cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.134
Presynaptic endocytic zone membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.712
GABA synthesis, release, reuptake and degradation	Reactome Pathways 2014	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
BICR10	DepMap CRISPR Gene Dependency	1.0	2.09971
Schizoaffective disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.344
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Synaptic vesicle, readily releasable pool	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.44
abnormal head morphology	MPO Gene-Phenotype Associations	1.0	null
GABA-ergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.315
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07819
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.697
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cleft secondary palate	MPO Gene-Phenotype Associations	1.0	null
LCLC97TM1	DepMap CRISPR Gene Dependency	1.0	2.31121
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19866
hsa-miR-3914	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mitochondrion-derived vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.696
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95865
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	1.4847
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A183-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Transmission across Chemical Synapses	Reactome Pathways 2024	1.0	null
Histaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.98
central nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.386
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63234
putamen, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.93748
exhibited	GeneRIF Biological Term Annotations	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.07283
Fatty Liver	CTD Gene-Disease Associations	1.0	1.70988
PMC8639147__F10	PFOCR Pathway Figure Associations 2024	1.0	null
Optic lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.317
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	140.273
PHETA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99854
CBX8	ENCODE Transcription Factor Targets	1.0	null
CHP126	CCLE Cell Line Gene Expression Profiles	1.0	1.57149
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reticular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40243
GSE110268_2_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CCNYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61697
AGGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74213
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amino acid transport	GO Biological Process Annotations 2015	1.0	null
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.21
abnormal facial morphology	MPO Gene-Phenotype Associations	1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.488
Pharyngeal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
Microtome section	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.702
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78399
organic acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
ADHD and autism ASD pathways	WikiPathways Pathways 2024	1.0	null
ATP5IF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91593
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF-21964334-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
abnormal locomotor activation	MPO Gene-Phenotype Associations	1.0	null
Neuron to neuron synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.667
TMEM216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66677
non-neuronal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.136
Bed nuclei of the stria terminalis, anterior division, anteromedial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3099
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.401
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ACP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74467
EGR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.0489
mantle zone of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44552
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Neuroepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.157
PMC9181267-mmc4.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
ANKRD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52311
Stromal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
HRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93944
TRAPPC6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08408
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.711729
PMC5417601-pone.0176879.s001.xlsx-Ctrl_vs_UCHL1_KD_result_DEseq_f-id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POR_KO_GDS1678_760_mouse_Colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.94
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell projection part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.893921
Meninx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.727
Cingulate gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.224
KLHDC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32471
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.227
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.867324
Alzheimer disease specific cell type	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.319
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DPY-21335234-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ocellus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.163
GSE136622_6_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Amnestic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LYL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42979
Internal plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.502
Neurotransmitter receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.711
Plasma membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.168
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
histamine-gated chloride channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.892
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955868
intermediate part of StrSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58437
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.4964
GSE86507,GSE86509_3_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Complement component C1q complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.274
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hyperkinesia	DisGeNET Gene-Phenotype Associations	1.0	null
Seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.942
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.271256
Inferior olivary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.155
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15832
LRATD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74053
NCIH322	CCLE Cell Line Gene CNV Profiles	1.0	2.73974
Mantle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.26
nitrogen compound transport	GO Biological Process Annotations 2025	1.0	null
TRAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32787
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.9186
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus incertus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22926
Pars reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.165
gamma-aminobutyric acid:proton symporter activity	GO Molecular Function Annotations 2023	1.0	null
Exocytic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.71
Prader-Willi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
Mushroom body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.427
Somatosensory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.686
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1059
JARID2-20064375-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EXOSC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02704
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WL-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199606_1_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ASH2L-23239880-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Secretory vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.904
DMS79	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72431
MYL12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64777
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Superior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.732
Sleep apnea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
KLRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04204
UBTFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22889
FRAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64051
SREBF2	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.794
Hypertension	CTD Gene-Disease Associations	1.0	1.31387
Compound eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QGP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35712
PMC11976269-41375_2025_2519_MOESM3_ESM.xlsx-ChIP_GATA2_Cluster_B-GeneName_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.942549
not applicable_asthma_GSE43696_369_mouse_bronchial epithelial cell	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Olfactory nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
JARID2-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Motor Skills Disorders	CTD Gene-Disease Associations	1.0	1.21076
KIF18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.991349
HELZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34404
Head capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.621
PUS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40058
BON-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.22501
Glycinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.707
RNF149	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5899
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049878
aging	GO Biological Process Annotations 2015	1.0	null
Axon collateral	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.391
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chromaffin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.18859
GABAergic synapse	KEGG Pathways 2026	1.0	null
Transport of inorganic cations/anions and amino acids/oligopeptides	Reactome Pathways 2014	1.0	null
hsa-miR-876-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
abnormal mouth morphology	MPO Gene-Phenotype Associations	1.0	null
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864649
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31268
Aorta smooth muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
Dendritic shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.212
Plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.938
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061123
Scalp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.951
External plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.902
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.7043
Astroglia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.502
Lysosomal proton-transporting V-type ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.518
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14525
Proteinuria	CTD Gene-Disease Associations	1.0	1.06406
dendritic spine head	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.300311
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.53126
FCSK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56702
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.69218
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	2.41672
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
axon part	GO Cellular Component Annotations 2015	1.0	null
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.864649
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.912726
Dorsal globus pallidus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
outer CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.972825
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pia mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
Eating disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.729
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06729
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14513
Nidopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
Intercalated cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.949
GSE145915_0_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4492	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
pineal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.19597
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.938412
QGP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38122
MYOG	ENCODE Transcription Factor Targets	1.0	null
Autosomal dominant cerebellar ataxia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fetal alcohol spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.203
tegmentum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.319498
FTC133	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69081
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.05785
outer	GeneRIF Biological Term Annotations	1.0	null
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.900296
Cell body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.974
FAM98A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18569
SNUC1	CCLE Cell Line Gene CNV Profiles	1.0	1.65238
SOX2	ChEA Transcription Factor Targets	1.0	null
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5095-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
axon part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
retina	GeneRIF Biological Term Annotations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6356-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41677
hsa-miR-339-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
NEUROD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32131
cytoplasmic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.274468
Pain agnosia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.373
neutral amino acid transport	GO Biological Process Annotations 2015	1.0	null
Nicotine addiction	KEGG Pathways 2026	1.0	null
clathrin-sculpted gamma-aminobutyric acid transport vesicle membrane	GO Cellular Component Annotations 2023	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.724
amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.377773
primary auditory cortex (core)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.834931
Primary dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.242
TRIML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63116
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Amino acid transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.69
NCIH747	CCLE Cell Line Gene CNV Profiles	1.0	1.37011
primary atelectasis	MGI Mouse Phenotype Associations 2023	1.0	null
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VEGFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47288
Craniofacial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.515
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83847
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.053
Granule cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.292
ARPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25912
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
glycine-tRNA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.142
GSE210682_2_v_1_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.64
glycine:proton antiporter activity	GO Molecular Function Annotations 2025	1.0	null
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.35557
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1938
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15411
Head muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.107
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mitochondrion	LOCATE Predicted Protein Localization Annotations	1.0	null
Motor cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.408
TBCEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85879
GSE151829,GSE151831_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
exocytic vesicle membrane	GO Cellular Component Annotations 2023	1.0	null
Dendritic tree	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.116
Liver hepatocellular carcinoma_LIHC_TCGA-XR-A8TG-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Optic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.337
ZNF587	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0891
Cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.202
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19592