association	dataset	threshold value	standardized value
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4851
Perturb_12843_KO_Tet2_SRP338315	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.63846
Renal tubular acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.211
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2531
CRCGN009_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.73973
phosphate ion homeostasis	GO Biological Process Annotations 2015	1.0	null
Calvarium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
ATP-binding cassette (ABC) transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.859
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HB-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.407
apical part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.930774
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4065
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00444
cystinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.47753
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.842793
Microgametophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2897
Pancreas	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.21956
GABARAP	Hub Proteins Protein-Protein Interactions	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-4R-AA8I-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal Dominant Hypophosphatemic Rickets	DisGeNET Gene-Disease Associations	1.0	null
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050047
abnormal skeleton physiology	MPO Gene-Phenotype Associations	1.0	null
protein complex binding	GO Molecular Function Annotations 2015	1.0	null
intestinal wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.245491
BRD-K03376048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91846
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PMC8040704-jcav12p2673s2.xlsx-Down-regulated_genes_in_EBF1-Unnamed_5_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
Acute kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100508_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.43476
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03538
BRD-K22087390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18948
GUSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42976
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_upregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8402
skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046372
KDM2B-26808549-CHIP-SEQ-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
oxoacid metabolic process	GO Biological Process Annotations 2015	1.0	null
kidney	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_SK-N-SH_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mononuclear cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066748
BRD-K84170953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06641
BRD-K10191318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13733
PMC5895607-41388_2017_42_MOESM4_ESM.xls-geneNames-Extended_Data_3_Gene_list_of_SRC-1_targets_which_contain_STAT1_binding_motifs_from_LY2_cell_RNAseq_data_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
BRD-K38571893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02479
Glycinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.665
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Distal tubular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.315
Perturb_9767_KO_Cdk1_SRP287303	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.26948
ZFPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98728
CRY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94589
piinduced	GeneRIF Biological Term Annotations	1.0	null
BRD-K34489277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51362
GTF2IRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32551
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Osteogenesis imperfecta	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84849
GSE113221,GSE113968_4_v_1_prdm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.152196
ADRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08746
SMAD1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64461
Ameloblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.923
Maltose transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.513
Vitamin D Deficiency	DisGeNET Gene-Disease Associations	1.0	null
body of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30951
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.845646
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	5.78856
BRD-K25075258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16017
Proximal tubular cell_Epithelium_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Unconventional myosin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.097
sodium-dependent phosphate transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6791
Lung adenocarcinoma_LUAD_TCGA-78-8660-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K75840180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28397
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79912
Asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
ZFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57356
liver	HPA Tissue Gene Expression Profiles	1.0	0.96537
OCT4-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K32983008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64969
CRCGN016_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16284
Tooth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
Fanconi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.658
intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.501182
NCIH508	Achilles Cell Line Gene Essentiality Profiles	1.0	1.77747
Primary somatosensory area, trunk	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20494
integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045806
Hypokalemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.422
tris(2-carboxyethyl)phosphine	CTD Gene-Chemical Interactions	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22882
lethality during fetal growth through weaning	MPO Gene-Phenotype Associations	1.0	null
abnormality of muscle physiology	HPO Gene-Disease Associations	1.0	null
Mitotic spindle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
biological regulation	GO Biological Process Annotations 2015	1.0	null
artery disease	GWASdb SNP-Disease Associations	1.0	0.357276
superficial stratum of PCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22523
pth	GeneRIF Biological Term Annotations	1.0	null
KIJK	CCLE Cell Line Gene CNV Profiles	1.0	1.60277
Sodium-coupled phosphate cotransporters	Reactome Pathways 2024	1.0	null
NCI-H2291	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
BRD-K62236460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39795
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46455
basolateral amygdaloid nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87788
response to vitamin a	GO Biological Process Annotations 2015	1.0	null
CRCGN015_MCF10A_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3225
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
preweaning lethality	MPO Gene-Phenotype Associations	1.0	null
abnormal kidney morphology	MPO Gene-Phenotype Associations	1.0	null
dentinogenesis	GO Biological Process Annotations 2015	1.0	null
intermediate stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28061
NCI-H1963	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Renal pyramid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.386
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DK-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased circulating phosphate level	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K48717228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08696
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.663191
Hypochromic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
GMS10	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49149
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.778
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96649
BRD-K36523261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84169
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.92423
BRD-K99660943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23328
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9225
SRXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17285
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K24479270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07228
intermediate stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20686
lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.067201
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.47825
FST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62047
superficial stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58164
response to metal ion	GO Biological Process Annotations 2023	1.0	null
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05517
primary hyperoxaluria	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.401199
HT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.07915
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4689	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
CRCGN010_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34283
U118MG	CCLE Cell Line Gene Expression Profiles	-1.0	-2.14922
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.26312
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4749
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
including	GeneRIF Biological Term Annotations	1.0	null
Amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.514
PA-TU-8902	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
monovalent inorganic anion homeostasis	GO Biological Process Annotations 2015	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
arsenate ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28089
Medullary reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59052
BRD-K66655211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47542
BRD-K30823221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1067
Trunk kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.7
Mitosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.643
UMR-106 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.499
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28905
Primary somatosensory area, upper limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56019
Lung adenocarcinoma_LUAD_TCGA-50-5946-02A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spinal stenosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_11318_KO_Nr1d1/Nr1d2_SRP241717	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.4751
renal insufficiency	HPO Gene-Disease Associations	1.0	null
SOX3-22085726-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.36275
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.321
hsa-miR-762	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Slit diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.864
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_26_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
compartmentalization	GeneRIF Biological Term Annotations	1.0	null
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.31409
496100642_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6018
Epiphysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
BRD-K23220745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65882
CRCGN016_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6314
HEB	MotifMap Predicted Transcription Factor Targets	1.0	null
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05288
BRD-A20182314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10192
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.948003
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.52671
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.84172
basis	GeneRIF Biological Term Annotations	1.0	null
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.64077
AKAP9	Pathway Commons Protein-Protein Interactions	1.0	null
Basolateral amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08991
CCL7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0045449
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA41-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEL	CCLE Cell Line Gene Expression Profiles	1.0	2.04351
PMC4390530-NIHMS667786-supplement-1.xlsx-Sheet1-Supplementary_Table_2_Genes_closest_to_AR_induced_ASH2L_peaks_AR	Rummagene Transcription Factor Associations 2026	1.0	null
profoundly	GeneRIF Biological Term Annotations	1.0	null
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.69685
RAD21_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7853
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K57250790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35441
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.840122
BRD-K10416099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17626
M07E	DepMap CRISPR Gene Dependency	1.0	3.46228
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.832
PMC9618568-41467_2022_34255_MOESM4_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K39566424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56544
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20578
abnormal total tissue mass	MPO Gene-Phenotype Associations	1.0	null
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.8439
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.89921
affected	GeneRIF Biological Term Annotations	1.0	null
pronephros	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.248683
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.337
BRD-K23204256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38546
GSE229468,GSE229471_2_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.61273
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21947
Glycosuria	DisGeNET Gene-Phenotype Associations	1.0	null
Urolithiasis	DisGeNET Gene-Disease Associations	1.0	null
Cortical collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.476
Cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
LC1F	CCLE Cell Line Gene CNV Profiles	1.0	1.40802
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
PMC12036091-jcav16p2321s1.pdf-27-OVOL1_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
response to external stimulus	GO Biological Process Annotations 2015	1.0	null
BRD-K40418847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51334
abnormality of the upper urinary tract	HPO Gene-Disease Associations	1.0	null
Osteopenia	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81R-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02559
SR	GDSC Cell Line Gene Expression Profiles	1.0	2.10224
Epidermal nevus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.425
PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
slc34a1	GeneRIF Biological Term Annotations	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Synostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.36
Primary somatosensory area, mouth	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06175
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
decreased grip strength	IMPC Knockout Mouse Phenotypes	1.0	null
hsa-miR-663b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.436
Dentin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.139
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.577581
PMC6113333-41598_2018_31192_MOESM11_ESM.xlsx-Sheet1-H1_NFIC_NFIC	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of ion transport	GO Biological Process Annotations 2015	1.0	null
RAD21_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3150b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
BRD-K94728263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21305
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.309986
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
cell surface	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.918579
solute:sodium symporter activity	GO Molecular Function Annotations 2023	1.0	null
Bone Diseases, Developmental	CTD Gene-Disease Associations	1.0	2.88009
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
short stature	HPO Gene-Disease Associations	1.0	null
taken	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-A5EL-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K91905575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4027
abnormal renal physiology	GWASdb SNP-Phenotype Associations	1.0	0.309171
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.85592
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52630978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19186
RS411	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.0426
trivalent inorganic anion homeostasis	GO Biological Process Annotations 2015	1.0	null
Glomerular filtration rate	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.55229
response to thyroid hormone	GO Biological Process Annotations 2015	1.0	null
Excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.651
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.19161
urate transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelial stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.357802
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41302
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
their	GeneRIF Biological Term Annotations	1.0	null
EGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98549
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85544
Alveolar bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.991
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5988-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.053
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5866
intermediate stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19152
abnormality of carbohydrate metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
LARP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94568
myeloid progenitor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06467
BRD-K62418408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06308
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K88000297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64895
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.995823
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.58007
CRCGN016_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.77385
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
interact	GeneRIF Biological Term Annotations	1.0	null
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16555
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.8994
protein complex subunit organization	GO Biological Process Annotations 2015	1.0	null
BRD-K36671227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35866
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13539
hsa-miR-4645-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Type II Na+/Pi cotransporters	Reactome Pathways 2024	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mo-B cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
Spinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6X2-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65933652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19458
A1207	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.22327
SIGIRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71598
BRD-K83436911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14175
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urinary tract obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.14111
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.28478
plant-type vacuole membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.658
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K09487932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28134
Glomerular filtration rate in non diabetics (creatinine)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.33979
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84162
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.231934
Human - Kidney - L2 - Proximal Tubule Epithelial Segment 1	HuBMAP Azimuth Cell Type Annotations	1.0	null
Lateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27296
intermediate stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06351
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35582
single-organism localization	GO Biological Process Annotations 2015	1.0	null
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.84087
hsa-miR-4696	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
DAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19516
HEL	GDSC Cell Line Gene Expression Profiles	1.0	2.76671
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30839
DOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54633
BRD-K51757923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27837
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.07957
BRD-K00920341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42181
response to stimulus	GO Biological Process Annotations 2015	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
DALRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76292
BRD-K28079391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8165
response to steroid hormone	GO Biological Process Annotations 2015	1.0	null
SOX2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
reproductive system phenotype	MPO Gene-Phenotype Associations	1.0	null
cation-transporting ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.602
BRD-K10196668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29695
anion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99827210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52259
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.912
Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.908
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12099
BRD-K08650286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.366
BRD-K16733272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.959
GSE62843,GSE64370_0_v_3_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.693
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Decreased total neutrophil count	ClinVar Gene-Phenotype Associations 2025	1.0	null
SAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1199
BRD-K11671824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63681
Perturb_10286_KO_Ypel3_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.6791
r10 part of vagal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10283
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Arsenates	CTD Gene-Chemical Interactions	1.0	null
Hypervitaminosis D	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.22
properties	GeneRIF Biological Term Annotations	1.0	null
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058278
renal tubular transport disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.125019
Renal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.343
KMM1	CCLE Cell Line Gene Expression Profiles	1.0	2.25243
RXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
perinuclear region of cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
deletion	GeneRIF Biological Term Annotations	1.0	null
BRD-K87516578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33183
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Recycling endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.271
Polygenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.922
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.997105
BRD-K02688026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99521
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
cell projection membrane	GO Cellular Component Annotations 2025	1.0	null
bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.08238
SNU119	CCLE Cell Line Gene CNV Profiles	1.0	2.28807
abnormal urine homeostasis	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K31898235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14205
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.80268
BRD-K12313989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1499
GSE112860_3_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phagocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.454019
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OP-11A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FUOV1	CCLE Cell Line Gene CNV Profiles	1.0	2.53452
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TQ-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43524
ZNF568	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60321
abnormal urine homeostasis	MPO Gene-Phenotype Associations	1.0	null
BRD-K43496057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51024
Disease	Reactome Pathways 2024	1.0	null
RAB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48927
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82802
BRD-K71737889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71332
blast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062481
abnormal birth weight	MPO Gene-Phenotype Associations	1.0	null
TFAP2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.477
DMS153	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6178
NCI-H1993	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.98315
abnormal locomotor activation	MPO Gene-Phenotype Associations	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:D03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29818
regulation of ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
TFCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10801
lateral hypothalamic area, tuberal part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.944326
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.85896
BRD-K65829768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00416
CXCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76537
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pseudopseudohypoparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.87539
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30468
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90218
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.11325
HCC827GR5	CCLE Cell Line Gene Expression Profiles	1.0	1.39013
response to staurosporine	GO Biological Process Annotations 2015	1.0	null
Myosin VI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.297
renal phosphate wasting	HPO Gene-Disease Associations	1.0	null
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.104267
Vitamin D-dependent rickets type 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.595
BRD-K54212583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62805
osteopenia	HPO Gene-Disease Associations	1.0	null
hsa-miR-19b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Metabolic Alkalosis	DisGeNET Gene-Disease Associations	1.0	null
hyperphosphatemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.946186
CRCGN011_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07398
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.04335
r8 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27917
Urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.225
Molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.692
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K26395018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94901
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46044
hsa-miR-764	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.79469
MDAMB468	DepMap CRISPR Gene Dependency	1.0	3.5187
FOXA1-26743006-CHIP-SEQ-LNCAP-ABL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
indole-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
apical plasma membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K25322420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6301
NFIA_Deficiency_GDS2775_639_mouse_Embryonic brains (at E18)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Perturb_11071_KO_Slc10a1_SRP174097	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.2995
CRCGN010_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07126
ADCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63871
SW900	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
pulmonary alveolar microlithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.08873
Amino acid transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.731
HIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13165
positive regulation of ion transport	GO Biological Process Annotations 2015	1.0	null
flumetasone-2551	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1541
Liddle syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
r6 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0463
hypercalcemia	GeneRIF Biological Term Annotations	1.0	null
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.5716
mantle zone of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0944
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GJ-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73427605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47854
BRD-K00590556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10239
KD	DepMap CRISPR Gene Dependency	1.0	2.41328
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
r9 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07705
CRCGN017_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.85285
hsa-miR-1245b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
abnormality of bone mineral density	HPO Gene-Disease Associations	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219485
Type II Na+/Pi cotransporters	Reactome Pathways 2014	1.0	null
Mccune-Albright Syndrome	DisGeNET Gene-Disease Associations	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.900693
membrane raft	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4269881__F6	PFOCR Pathway Figure Associations 2024	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
carbohydrate derivative metabolic process	GO Biological Process Annotations 2015	1.0	null
membranous glomerulonephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.158266
hypercalcemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.794181
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.830938
16397240-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
Uremia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.664
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36391
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.97191
danazol-2038	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K91813753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09122
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
napiiia	GeneRIF Biological Term Annotations	1.0	null
Renal proximal tubule epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.728
variants	GeneRIF Biological Term Annotations	1.0	null
GSE147662_2_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.038
BRD-K32485819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30783
TGIF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0519
CDX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00546166
r9 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11161
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inorganic anion transport	GO Biological Process Annotations 2015	1.0	null
Dorsal motor nucleus of the vagus nerve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25884
response to parathyroid hormone	GO Biological Process Annotations 2015	1.0	null
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9
Synaptonemal structure	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.77
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.484349
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3913
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4654
496100328_TCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19613
Hyperthyroidism	DisGeNET Gene-Disease Associations	1.0	null
hsa-miR-4308	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
P63-20808887-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.64604
GSE127790_11_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
latamoxef-5609	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
response to cadmium ion	GO Biological Process Annotations 2025	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7178-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8626
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HDLM2	CCLE Cell Line Gene CNV Profiles	1.0	2.99009
Hematocrit Procedure	DisGeNET Gene-Phenotype Associations	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5589-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00683
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051415
BRD-K44664883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38892
Autosomal recessive infantile hypercalcemia	ClinVar Gene-Phenotype Associations 2025	1.0	null
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.714
GABPA	ENCODE Transcription Factor Targets	1.0	null
abnormal vitamin homeostasis	MPO Gene-Phenotype Associations	1.0	null
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Elevated Alkaline Phosphatase Of Bone Origin	DisGeNET Gene-Phenotype Associations	1.0	null
D2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40748
Osteogenesis imperfecta type 20	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.5528
Short Stature, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
KP-N-YN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.88406
secondary lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.211587
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.776
Perturb_10867_KO_Ghr_SRP269490	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.36854
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15432
reduced bone mineral density	HPO Gene-Disease Associations	1.0	null
BRD-K79887735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02736
Urolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.101
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.971
PMC10260405-41588_2023_1409_MOESM6_ESM.xlsx-ST12-Supplementary_Table_12_Most_likely_causal_genes_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K72588970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27072
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K57464717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01201
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.039
Glomerular filtration rate (creatinine)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.1301
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
chr5_177398068_C_T_b38	GTEx eQTL 2025	1.0	1.36889
ECC10	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49185
hypercalciuria	HPO Gene-Disease Associations	1.0	null
Autosomal recessive hypophosphatemic rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.608
infantile	GeneRIF Biological Term Annotations	1.0	null
BRD-K37049577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54816
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.851
BRD-K27228812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1588
SARS-CoV_24Hour_20090954_GSE17400	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.26531
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52N-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JL1	DepMap CRISPR Gene Dependency	1.0	2.60785
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A5-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crohn's disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.841
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42692
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.01549
PEER	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65786
CRCGN008_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.99425
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43513
indole metabolic process	GO Biological Process Annotations 2015	1.0	null
abnormality of the urinary system physiology	HPO Gene-Disease Associations	1.0	null
Pronephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.804
BRD-K07385991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3174
Panicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.728
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.50355
Lung adenocarcinoma_LUAD_TCGA-38-4625-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Central element	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.608
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04481
chronic obstructive pulmonary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.132367
methotrexate-3214	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
supramarginal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01451
abnormal glomerular filtration rate	GWASdb SNP-Phenotype Associations	1.0	1.13254
BRD-K44537081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16993
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN015_MCF10A_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.86727
BEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01618
perinuclear region of cytoplasm	GO Cellular Component Annotations 2015	1.0	null
Renal Phosphate Wasting	DisGeNET Gene-Phenotype Associations	1.0	null
Contractile vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.275
ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1987
marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065045
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.8743
Agranular insular area, ventral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00443
Brain Lower Grade Glioma_LGG_TCGA-HT-7601-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K13849122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07646
musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.583163
they	GeneRIF Biological Term Annotations	1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03205
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein complex assembly	GO Biological Process Annotations 2015	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
bepridil-4613	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OCIAML5	Achilles Cell Line Gene Essentiality Profiles	1.0	2.15532
16397240-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
Defective SLC34A1 causes hypophosphatemic nephrolithiasis/osteoporosis 1 (NPHLOP1)	Reactome Pathways 2024	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11071
Transport of inorganic cations/anions and amino acids/oligopeptides	Reactome Pathways 2014	1.0	null
TAL1	MotifMap Predicted Transcription Factor Targets	1.0	null
X-linked dominant hypophosphatemic rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.762
response to peptide	GO Biological Process Annotations 2015	1.0	null
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
DGKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3781
response to extracellular stimulus	GO Biological Process Annotations 2015	1.0	null
apical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.938322
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2566
brush border membrane	GO Cellular Component Annotations 2023	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34495
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.696699
olanzapine_rattus norvegicus_gpl1355_gse2547	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03963
Brain Lower Grade Glioma_LGG_TCGA-DB-A4X9-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10313_OE_hAPOL1_G2_SRP075245	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.8494
abnormal trabecular bone morphology	MPO Gene-Phenotype Associations	1.0	null
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A3-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUGC-3	GDSC Cell Line Gene Expression Profiles	-1.0	-2.30892
OVCAR8	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.28071
BRD-A39521712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17714
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HPAFII	DepMap CRISPR Gene Dependency	1.0	2.43849
BRD-K33573676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17285
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.777348
SULT4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11833
5q35 copy number variation	WikiPathways Pathways 2024	1.0	null
NBAS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00496234
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051462
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39081
Lung squamous cell carcinoma_LUSC_TCGA-85-8479-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
erythroid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.295655
abnormal blood homeostasis	MPO Gene-Phenotype Associations	1.0	null
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.33028
TM6SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22415
BRD-K39326623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67275
DLX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88418
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059449
17404395-TableS1c	GeneSigDB Published Gene Signatures	1.0	null
BRD-K09376136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01559
MT-CYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9444
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07075
hydronephrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.322637
Red blood cell count	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.91549
Infertility	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
external globus pallidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0069
all	GWASdb SNP-Phenotype Associations	1.0	0.056828
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68884923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29655
Renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
KPNYN	DepMap CRISPR Gene Dependency	1.0	2.68086
HOXB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5376
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP1R1A_KO_GDS1920_708_mouse_hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-4777-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Fanconi renotubular syndrome	ClinVar Gene-Phenotype Associations 2025	1.0	null
basolateral plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57973
CRCGN014_HEPG2_3H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43639
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mdck cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.535833
BRD-K15341710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13439
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.985792
Renal parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.985
regulation of sodium-dependent phosphate transport	GO Biological Process Annotations 2015	1.0	null
growth delay	HPO Gene-Disease Associations	1.0	null
BRD-K51228600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18294
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MALME3M	DepMap CRISPR Gene Dependency	1.0	2.26372
Osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.921
nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.060713
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46754
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.037
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.906699
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.910071
BRD-K28596345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02324
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01108
SW900	CCLE Cell Line Gene CNV Profiles	1.0	1.78195
abnormality of the urinary system physiology	GWASdb SNP-Phenotype Associations	1.0	0.286271
Primary hyperparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.102
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24598
aciduria	HPO Gene-Disease Associations	1.0	null
BRD-K21412601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35117
SLC27A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84733
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.568
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09267
abnormal mineral homeostasis	MPO Gene-Phenotype Associations	1.0	null
BRD-K64137284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16487
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01369
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
well	GeneRIF Biological Term Annotations	1.0	null
r10 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1455
Mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.111
superficial stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39832
cor pulmonale	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.304864
Principal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.347
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.70348
Familial (Fpah)	DisGeNET Gene-Disease Associations	1.0	null
Perturb_10322_KO_MYC_SRP310502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.362
decreased body weight	MPO Gene-Phenotype Associations	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
significant	GeneRIF Biological Term Annotations	1.0	null
BRD-K45845217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1726
Entorhinal area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43064
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47242
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.307
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31089
BRD-K75674991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05708
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18914
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
calcium metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.850354
abnormal sterol level	MPO Gene-Phenotype Associations	1.0	null
Pulmonary alveolar microlithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.334
Cotyledon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.868
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7M4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
response to lead ion	GO Biological Process Annotations 2015	1.0	null
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.1793
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.382
cos-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.396844
Serum parathyroid hormone levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.25229
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914276
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07072
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
BRD-K08179047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49763
Lung squamous cell carcinoma_LUSC_TCGA-22-4596-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03855
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.744
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3084
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
h4s	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.114
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.89229
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.115
CRCGN014_HEPG2_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.39217
layer 3 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67622
BRD-K61315077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31397
MYCN-28898695-NB1643-HUMAN-NERVE-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.232
T98G	COSMIC Cell Line Gene Mutation Profiles	1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02188
mantle zone of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38134
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08236
Xanthinuria type I	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
endocytosis	GeneRIF Biological Term Annotations	1.0	null
SNCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33172
lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.25547
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A4-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.060544
impairs	GeneRIF Biological Term Annotations	1.0	null
abnormal skeleton development	MGI Mouse Phenotype Associations 2023	1.0	null
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95822658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01359
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48948
alcohol metabolic process	GO Biological Process Annotations 2015	1.0	null
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.842793
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6134-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
jak2	GeneRIF Biological Term Annotations	1.0	null
BRD-K18488784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.94464
BRD-K63858518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28229
BRD-K10011427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11794
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.206
ATP-independent citrate lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.654
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14792
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
protein domain specific binding	GO Molecular Function Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8504-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K81881801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0721
Eggshell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.841
PMC8755441-mmc3.xlsx-IRF7-Up-Symbol_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04495110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12987
metal ion transport	GO Biological Process Annotations 2015	1.0	null
GSE217776,GSE217829_1_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-C9-A480-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypercalcemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.698
Medullary reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08206
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.26755
GSE180800,GSE180801_0_v_5_tex10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K90902537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86491
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney_CT1_Proximal Tubule Epithelial Cell Segment 1	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
sodium ion transport	GO Biological Process Annotations 2015	1.0	null
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03675
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EH-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66865641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04611
Epiphyseal growth plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.446
BRD-K07485506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80659
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.195639
Phosphates	CTD Gene-Chemical Interactions	1.0	null
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92204
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5442-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K15928912	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4235
nephrocalcinosis	GeneRIF Biological Term Annotations	1.0	null
DFFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03951
Metatarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.954
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.1432
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.67056
U87MG	CCLE Cell Line Gene Expression Profiles	-1.0	-2.18258
congestive heart failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.113734
mo-b cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.587629
BRD-K37657049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47911
HNRNPLL_02_125	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.02237
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE86507,GSE86509_7_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Temporal association areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60598
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.0755
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.064857
response to oxygen-containing compound	GO Biological Process Annotations 2015	1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_upregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
EPCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40051
CCNF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89472
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, mouth, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79243
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.32857
cellular response to hormone stimulus	GO Biological Process Annotations 2015	1.0	null
HSP90AB1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K78082598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72633
ZNF496	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77624
piriform cortex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00731
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.43136
lobeline-2763	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.061
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08834
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10927_KO_Mettl3_SRP363782	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.36022
identical protein binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K71817712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49479
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2464
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.0495
Cluster of actin-based cell projections	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.784
FBXL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8536
496100321_HIP_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.37449
cellular component organization	GO Biological Process Annotations 2015	1.0	null
NVT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.978
Increased Susceptibility To Fractures	DisGeNET Gene-Phenotype Associations	1.0	null
Cystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.548
BRD-K71554049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37362
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9424
Pyloric cecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.595
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Proteinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.83
OVKATE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49028
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.35547
intermediate stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25677
reticular nucleus of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3272
BRD-K94803981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53137
POLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48277
AMO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
tropine-6264	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Osteoporosis	DisGeNET Gene-Disease Associations	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.73953
SPI1	ENCODE Transcription Factor Targets	1.0	null
BRD-K36804307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08294
Renal proximal tubule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.46
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2864
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.53667
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10582
Sodium-dependent phosphate transport protein	InterPro Predicted Protein Domain Annotations	1.0	null
GSE211224_2_v_1_donepezil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K73831546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.45927
BRD-K20590138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09292
Pinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.729
BRD-K87849910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7562
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K22135724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00387
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-A59K-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71381
affinity	GeneRIF Biological Term Annotations	1.0	null
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.105912
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0744
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Nephrolithiasis-Osteoporosis	DisGeNET Gene-Disease Associations	1.0	null
elevated tissue non-specific alkaline phosphatase	HPO Gene-Disease Associations	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.26264
nephrocalcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.939534
mutants	GeneRIF Biological Term Annotations	1.0	null
ETV2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5663
chr5_177390142_G_T_b38	GTEx eQTL 2025	1.0	1.39753
response to growth hormone	GO Biological Process Annotations 2015	1.0	null
Perturb_10280_KO_Mid1ip1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.2739
Perturb_11065_KO_Mettl3_SRP363782	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.46669
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26373865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48045
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.52802
BRD-K16503119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70612
aminoglycoside antibiotic metabolic process	GO Biological Process Annotations 2015	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.473
abnormal circulating hormone level	MPO Gene-Phenotype Associations	1.0	null
GSE137144_2_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74566
15902281-TableS1e	GeneSigDB Published Gene Signatures	1.0	null
purine-pyrimidine metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.199
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1734	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1806	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
abnormality of the kidney	HPO Gene-Disease Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-AA26-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
siblings	GeneRIF Biological Term Annotations	1.0	null
periventricular stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05794
r6 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20686
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.921386
TM6SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09518
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZCCHC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21933
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.46775
BRD-K97588749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03079
ENTPD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22295
MAMSTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90632
Lung adenocarcinoma_LUAD_TCGA-49-6761-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.80969
abnormality of calcium homeostasis	HPO Gene-Disease Associations	1.0	null
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reduced fertility	MPO Gene-Phenotype Associations	1.0	null
SW156	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3137
Bartter disease type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.341
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60311
BRD-K78400597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31758
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
Hyperphosphatemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.991
hsa-miR-3173-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.299
Lung adenocarcinoma_LUAD_TCGA-38-4627-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31407552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40569
ZNF384	ENCODE Transcription Factor Targets	1.0	null
apical	GeneRIF Biological Term Annotations	1.0	null
Pseudohypoaldosteronism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.173057
Xanthinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.333
BRD-K95927760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65412
ZNF365	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00501764
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.0144
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS12BM	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.29237
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08413
modify	GeneRIF Biological Term Annotations	1.0	null
increases	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8011-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
XPodNet - protein-protein interactions in the podocyte expanded by STRING(Mus musculus)	WikiPathways Pathways 2014	1.0	null
Acute kidney tubular necrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.977316
H2BC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79144
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14457
CRCGN013_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.39478
Protein Kinase Inhibitors	CTD Gene-Chemical Interactions	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8324-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GNA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86419
idiopathic	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.73468
HNF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36517
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
decreased body size	MGI Mouse Phenotype Associations 2023	1.0	null
Renal corpuscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.08
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.94933
16397240-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69615
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32971
Hypogonadism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A44S-01A-12R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01817716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11985
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.563
BRD-K18519876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26466
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4784	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42108985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98177
Short Stature	DisGeNET Gene-Phenotype Associations	1.0	null
r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26443
ioversol-3026	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormal circulating phosphate level	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-19a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
BRD-K05205967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54941
TIAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21924
Stolon tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
BRD-K49742819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03978
outer CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45853
BRD-K89000000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08471
BRD-K64860662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44279
ZNF197	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22453
BRD-K28030757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22395
ZNF454	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22296
Lung squamous cell carcinoma_LUSC_TCGA-92-8063-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.4
LHX1_NULL MUTATION - Ablation_GDS1748_749_mouse_Embryonic kidneys (from day E18.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
EPCAM_OE_GDS4887_342_human_IL-28B	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K18601936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99519
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.252
excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
although	GeneRIF Biological Term Annotations	1.0	null
Calciphylaxis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.499
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81372
Oculocerebrorenal syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.922
Hartnup disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.093
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.84996
regulation of transmembrane transport	GO Biological Process Annotations 2015	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.66417
SUM185PE	DepMap CRISPR Gene Dependency	1.0	3.66938
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.02941
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049508
ok cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.87546
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52300725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72164
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.05789
phenformin-4283	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Microcytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
NCI-H716	GDSC Cell Line Gene Expression Profiles	1.0	1.51403
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58023
increased susceptibility to fractures	HPO Gene-Disease Associations	1.0	null
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.95255
endosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02747
Syp1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.933
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04481
BRD-K30727702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96342
Kidney	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NECTIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15783
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25932
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
LYL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
UNCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03863
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34234678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.56619
BRD-K85395981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13497
Perturb_10276_KO_31O21Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.35465
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
HMGN3_02_45	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.59991
BRD-K34797601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.35802
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.97953
region	GeneRIF Biological Term Annotations	1.0	null
amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058824
GSE85723,GSE85833_1_v_0_huwe1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gout	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39369
Rickets	DisGeNET Gene-Disease Associations	1.0	null
BRD-K84541452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78202
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.02132
BRD-K99455613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10698
r10 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25747
BRD-K40228963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2397
abnormality of metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.074701
IL2_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_15771_KO_Nrl_SRP219918	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.79302
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
Kidney stones	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.02218
Uterus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.848081
abnormal renal/urinary system morphology	MPO Gene-Phenotype Associations	1.0	null
R3HCC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49923
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
sotos syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.744766
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5967
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.947655
lethargy	MGI Mouse Phenotype Associations 2023	1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
phosphate ion homeostasis	GO Biological Process Annotations 2025	1.0	null
rickets	HPO Gene-Disease Associations	1.0	null
pinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.209858
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01188
arthropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.317909
r9 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99798
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18335
BCAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59896
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nephrolithiasis	HPO Gene-Disease Associations	1.0	null
abnormality of urine homeostasis	HPO Gene-Disease Associations	1.0	null
phagolysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.345314
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04481
ENTREP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44102
r9 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52195
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3WB-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMBRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87378
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endosome	GO Cellular Component Annotations 2015	1.0	null
PMC9248879-supp_gr.275831.121_Supplemental_Table_S2.xlsx-TP53-dependent_proteins-GeneName_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.0573
abnormal enzyme/coenzyme activity	HPO Gene-Disease Associations	1.0	null
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06622
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.72958
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56346
BRD-K69396470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03259
BRD-K73075421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15593
GSE215086_0_v_1_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
Fanconi renotubular syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.212
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spindle	GO Cellular Component Annotations 2023	1.0	null
SNU245	CCLE Cell Line Gene Expression Profiles	1.0	1.36221
cellular response to alkaloid	GO Biological Process Annotations 2015	1.0	null
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormal renal morphology	HPO Gene-Disease Associations	1.0	null
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36241
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
BRD-K95350313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10749
BRD-K54455139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38513
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9992
Osteomalacia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.957
germ plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.192423
PMC5079533__F4	PFOCR Pathway Figure Associations 2023	1.0	null
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9806
increased urine phosphate level	MGI Mouse Phenotype Associations 2023	1.0	null
COL5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76874
cerebrovascular disease	GWASdb SNP-Disease Associations	1.0	2.06032
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845342
MELHO	DepMap CRISPR Gene Dependency	1.0	2.77554
Ferroxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.732
BRD-K93040255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48184
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pole plasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.18796
NRK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.949
monolayer-surrounded lipid storage body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.046
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.940741
sites	GeneRIF Biological Term Annotations	1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Renal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3387
BRD-K91470977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91579
Renal tubular transport disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.635
K562	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
hsa-miR-342-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Enterocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.549
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08953
SNU-283	COSMIC Cell Line Gene Mutation Profiles	1.0	null
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3386
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
response to estradiol	GO Biological Process Annotations 2015	1.0	null
abnormal muscle physiology	MPO Gene-Phenotype Associations	1.0	null
Auditory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.61891
BRD-K45142472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10973
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOMM34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7393
Lung adenocarcinoma_LUAD_TCGA-75-6207-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.9693
stoneforming	GeneRIF Biological Term Annotations	1.0	null
BRD-K80715600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62516
BRD-K51697315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55387
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.5227
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18688395	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10949
SKNEP1	DepMap CRISPR Gene Dependency	1.0	3.43785
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47441131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38307
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.850395
abnormality of cation homeostasis	HPO Gene-Disease Associations	1.0	null
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.80236
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168807_6_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anomalies	GeneRIF Biological Term Annotations	1.0	null
NCIH2342	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69717
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anion homeostasis	GO Biological Process Annotations 2015	1.0	null
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.80666
Prostate adenocarcinoma_PRAD_TCGA-CH-5767-11B-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K55584718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43359
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1915	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_02_25	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	6.07682
heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048682
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.19528
BRD-K97741413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23566
BRD-K23112275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56996
Kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.742
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0233
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0305
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.43617
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EN1	JASPAR Predicted Transcription Factor Targets	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
anion transport	GO Biological Process Annotations 2015	1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.03093
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.032
Renal Insufficiency	CTD Gene-Disease Associations	1.0	1.05685
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.62624
protein dimerization activity	GO Molecular Function Annotations 2015	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.35631
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42E-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.59127
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3598
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976207
TBC1D16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32665
Renal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.666
MRPS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06858
PMC5918774-13287_2018_864_MOESM2_ESM.xls-sheet-AF_MSC_AND_fMSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
CYB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66717
Kidney Calculi	DisGeNET Gene-Disease Associations	1.0	null
Fibula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.8
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	1.1793
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
BRD-K29802952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98769
NCIH211	CCLE Cell Line Gene CNV Profiles	-1.0	-1.335
CRCGN014_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4406
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
FAHD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.029
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11087
BRD-K12524104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34949
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045149
glycosuria	HPO Gene-Disease Associations	1.0	null
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5691-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28655
Late endosome lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.568
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anatomical structure morphogenesis	GO Biological Process Annotations 2015	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
SMC4-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.566
irinotecan_rattus norvegicus_gpl1355_stomach_gds3466	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ficolin-1-rich granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.722
CingulateCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.977291
pdz domain binding	GO Molecular Function Annotations 2015	1.0	null
r4 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42943
Acute Myeloid Leukemia_LAML_TCGA-AB-2992-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Posterolateral visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80988
GSE84922,GSE84924_4_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.363
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041819
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Proximal tubule cell_Kidney_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
glomerulonephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.064512
hsa-miR-2467-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Bartter disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.863
G361	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62319
cancellous bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.275094
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_24_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.24486
abnormal skeleton development	MPO Gene-Phenotype Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7994-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66311249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33263
Bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.742
OLFML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4405
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
encoding	GeneRIF Biological Term Annotations	1.0	null
Kidney failure	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.566
Complex cortical dysplasia with other brain malformations 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03867
NCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14948
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.931298
Primary hypomagnesemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
SLC9A3R2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE165174,GSE165175_0_v_1_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49683
cefapirin-6790	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Galactosemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
hsa-miR-3177-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JT-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27849471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1655
hsa-miR-3607-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Brush border membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE203060_0_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08993
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.895629
hematopoietic system disease	GWASdb SNP-Disease Associations	1.0	0.347289
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.55
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.90869
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.604
response to cadmium ion	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AQ-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
16498405-TableS4	GeneSigDB Published Gene Signatures	1.0	null
CRCGN015_MCF10A_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49107
r9 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21157
Kenny-Caffey syndrome type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRRC58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94224
mechanisms	GeneRIF Biological Term Annotations	1.0	null
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81322
CHD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41985
Congenital sucrase-isomaltase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.76105
cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.5656
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nuclear	GeneRIF Biological Term Annotations	1.0	null
inorganic anion transport	GO Biological Process Annotations 2025	1.0	null
Cancellous bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.559
hsa-miR-940	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Glycogen Storage Disease	DisGeNET Gene-Disease Associations	1.0	null
BRD-K54467766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03479
phosphate ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
immune system disease	GWASdb SNP-Disease Associations	1.0	0.200836
UMRC7	DepMap CRISPR Gene Dependency	1.0	3.30684
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.769
glycerol-3-phosphate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.808
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
IZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.96871
GATA3-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
posterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31167
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BR-01A-32R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.60316
MYL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76172
KDELR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25776
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39081
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.859195
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04991
MEIS2_02_30	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.24793
SLC-mediated transmembrane transport	Reactome Pathways 2014	1.0	null
MRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47498
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PG-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chromosomal deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
PHF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04634
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, trunk, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4055
BRD-K54111001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17996
PLXNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55735
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FU97	CCLE Cell Line Gene Expression Profiles	1.0	1.88058
496100373_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.32245
BRD-K47415214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00534
cellular response to chemical stimulus	GO Biological Process Annotations 2015	1.0	null
hsa-miR-432	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Hypercalcemia	ClinVar Gene-Phenotype Associations 2025	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.164
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18859
hypercalciuric	GeneRIF Biological Term Annotations	1.0	null
BRD-K18623962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16331
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-62-8395-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K39193666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76742
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
small intestine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.179665
Lateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58568
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.07975
regulation of membrane potential	GO Biological Process Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6154-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09634
Tibia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.406
abnormality of phosphate homeostasis	HPO Gene-Disease Associations	1.0	null
previous	GeneRIF Biological Term Annotations	1.0	null
RH-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.54726
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
annulus fibrosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.366007
macromolecular complex binding	GO Molecular Function Annotations 2015	1.0	null
CRCGN012_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69307
P300-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BLMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68621
interleukin-12 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.21646
Raf-1_OE_GDS1925_166_human_Estrogen receptor (ER) alpha positive MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
METTL25B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38949
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
renal	GeneRIF Biological Term Annotations	1.0	null
Episodic ataxia type 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
Bone structure disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.516
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
Measles Chicago-1_24Hour_16492729_GSE980	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.59264
Glomerular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.957
CNTNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44786
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
Primary hyperaldosteronism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24601
SNU626	DepMap CRISPR Gene Dependency	1.0	2.36634
Proximal convoluted tubular cell_Kidney_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.06008
abnormal body weight	MPO Gene-Phenotype Associations	1.0	null
Perturb_11242_KO_Sirt6_SRP190930	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.19597
BRD-K45677596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93542
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.847339
BRD-K08527280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40538
Osteosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3313-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.412011
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.95577
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phosphate-containing compound metabolic process	GO Biological Process Annotations 2023	1.0	null
Measles Chicago-1_6Hour_16492729_GSE980	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.76242
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NF-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K48129913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47607
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2-21901280-H4IIE-RAT	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55800245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06322
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.978503
urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE112860_3_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EMSY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53081
BL41	CCLE Cell Line Gene Expression Profiles	1.0	1.5451
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cystinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.989
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2998
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.977316
BRD-K96764878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61755
Renal glycosuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.576
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.85542
Anterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78615
Perturb_5441_KO_Zeb2_SRP261907	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.9758
CTXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51411
Prostate adenocarcinoma_PRAD_TCGA-J4-A67M-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phosphate ion transport	GO Biological Process Annotations 2025	1.0	null
LMO2-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20382
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
BSPRY	Pathway Commons Protein-Protein Interactions	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.931298
BRD-K22944782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17271
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus pulposus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.918633
BRD-K43306617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06149
nephrocalcinosis	MPO Gene-Phenotype Associations	1.0	null
BRD-K04498687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69617
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08729
Hairy cell leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.605
MM386	DepMap CRISPR Gene Dependency	1.0	2.30719
familial	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41687
EFO21	DepMap CRISPR Gene Dependency	1.0	2.21868
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11223_KO_Mkrn1_SRP149173	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.43613
Hereditary angioedema	ClinVar Gene-Phenotype Associations 2025	1.0	null
active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
delayed bone ossification	MPO Gene-Phenotype Associations	1.0	null
Nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.807
Mineral absorption	KEGG Pathways 2026	1.0	null
PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
models	GeneRIF Biological Term Annotations	1.0	null
BRD-K39159284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17308
napiiic	GeneRIF Biological Term Annotations	1.0	null
BRD-K69918256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07902
SW954	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K95593113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25052
Hypochromic microcytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
CRCGN016_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.71025
sodium:potassium-exchanging ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.624
abnormal voluntary movement	MPO Gene-Phenotype Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LPAR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05882
GSE157594_5_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
IOMMLEE	CCLE Cell Line Gene Expression Profiles	1.0	1.87523
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5082
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.371216
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC_INHIBITION - trichostatin A_GDS2452_709_human_Endothelial cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09267
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.5833
hsa-miR-4802-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.15806
GSE215086_5_v_0_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K21420222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14187
Hypophosphatemic nephrolithiasis/osteoporosis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.989
CRCGN015_MCF10A.TP53.M_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.75179
BRD-K12202458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29298
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04805
BRD-K05411364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58225
Calcium levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
basolateral plasma membrane	GO Cellular Component Annotations 2015	1.0	null
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.38278
Lung squamous cell carcinoma_LUSC_TCGA-96-8170-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32492
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53241
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r6 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01409
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.15596
EB1	CCLE Cell Line Gene Expression Profiles	1.0	1.48054
BRD-K86935536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12675
Hypophosphatemic Rickets	DisGeNET Gene-Disease Associations	1.0	null
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0667
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
glycoside metabolic process	GO Biological Process Annotations 2015	1.0	null
abnormality of the nephron	HPO Gene-Disease Associations	1.0	null
kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
NRK-52E cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.883
RCOR3	ChEA Transcription Factor Targets	1.0	null
COV362	CCLE Cell Line Gene Expression Profiles	1.0	1.43745
Grb2-Shc complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.651
cellular response to organonitrogen compound	GO Biological Process Annotations 2015	1.0	null
BRD-K61687409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03576
BRD-K25039453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06436
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4525
Digenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.953
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9797
monocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075149
Glomerulosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14851
Lung squamous cell carcinoma_LUSC_TCGA-L3-A4E7-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.737
F36P	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80301
Secondary hyperparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.451
skin atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.651298
bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.623359
cell part	GO Cellular Component Annotations 2015	1.0	null
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.52838
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19787
CHST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51241
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.931298
enterocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214017
Prostate adenocarcinoma_PRAD_TCGA-G9-6385-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4219345-1471-2121-14-52-S3.xlsx-BORIS_hNP1-Gene_Symbol_CTCFL	Rummagene Transcription Factor Associations 2026	1.0	null
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BtuCD complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.536
nephrocalcinosis	MGI Mouse Phenotype Associations 2023	1.0	null
Urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.728
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46789
abnormal eating behavior	MGI Mouse Phenotype Associations 2023	1.0	null
cellular response to organic cyclic compound	GO Biological Process Annotations 2015	1.0	null
CRCGN014_HEPG2_3H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74783
JM1	DepMap CRISPR Gene Dependency	1.0	4.26121
Metal metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.762
BRD-K11979048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34548
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
IgA glomerulonephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
r8 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23474
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33716
EBF	MotifMap Predicted Transcription Factor Targets	1.0	null
large latent transforming growth factor-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.447656
response to nutrient levels	GO Biological Process Annotations 2015	1.0	null
hela cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.117634
Hypercalciuria	CTD Gene-Disease Associations	1.0	2.88009
NCIH2882	DepMap CRISPR Gene Dependency	1.0	4.1486
496100349_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23162
Claustrum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0743
HG3	DepMap CRISPR Gene Dependency	1.0	3.17948
BRD-K16279128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56878
Perturb_17322_KO_Ppp2ca_SRP330476	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.3744
LIMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63797
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3903
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7395
REH	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.14067
terguride-3082	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K34977825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65096
mantle zone of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17436
sodium-dependent phosphate transport	GO Biological Process Annotations 2023	1.0	null
abnormal cornea morphology	IMPC Knockout Mouse Phenotypes	1.0	null
downregulation	GeneRIF Biological Term Annotations	1.0	null
Tubulointerstitium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.54
intermediate stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22171
renal	GAD High Level Gene-Disease Associations	1.0	0.295739
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12176
LEF1-29337183-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
Basolateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.113
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Renal outer medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
Lung adenocarcinoma_LUAD_TCGA-62-A472-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.943352
periventricular stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10473
frontal pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02583
parvocellular part of r8LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61511
Milk-Alkali Syndrome	DisGeNET Gene-Disease Associations	1.0	null
phosphate ion transport	GO Biological Process Annotations 2023	1.0	null
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.6233
regulation of localization	GO Biological Process Annotations 2015	1.0	null
r10 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39679
x-linked hypophosphatemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.69133
BRD-K61168922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11408
membrane region	GO Cellular Component Annotations 2015	1.0	null
Mesenchymal cell neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.797
abnormality of the kidney	GWASdb SNP-Phenotype Associations	1.0	1.68604
Perturb_11107_KO_Cpt2_SRP303636	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.9208
organ morphogenesis	GO Biological Process Annotations 2015	1.0	null
BRD-K34542210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48196
MSANTD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83297
macromolecular complex subunit organization	GO Biological Process Annotations 2015	1.0	null
response to cadmium ion	GO Biological Process Annotations 2023	1.0	null
ETV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90449
RCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.39638
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
GSE163862_0_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
sodium-dependent phosphate transport	GO Biological Process Annotations 2015	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.973213
BRD-K18176829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10663
Parathyroid adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
Hematocrit	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ncoa_22072566_ly2_lof_human_gpl570_gds4095	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	2.22133
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	45.2108
Glomerular Filtration Rate	DisGeNET Gene-Phenotype Associations	1.0	null
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83751422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27109
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.83857
Sensorineural hearing loss	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
overall	GeneRIF Biological Term Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A0YX-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.795411
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP3R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25129
response to organic substance	GO Biological Process Annotations 2015	1.0	null
PMC5577301-in-17-237-s001.xls-AR_downregulated_DEGs-Kidney_GDS724_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Primary immunodeficiency disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.235
calcium	GeneRIF Biological Term Annotations	1.0	null
monovalent inorganic cation transport	GO Biological Process Annotations 2015	1.0	null
PMC8891017-41586_2022_4394_MOESM4_ESM.xlsx-ST6_-_MAF_enrichment-Unnamed_4_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
part	GeneRIF Biological Term Annotations	1.0	null
abnormal circulating enzyme level	MPO Gene-Phenotype Associations	1.0	null
abnormal consumption behavior	MPO Gene-Phenotype Associations	1.0	null
glis2_17618285_kidney_lof_mouse_gpl2897_gds2817	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.917391
MFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99543
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chloride channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.039
Macropinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.677
abnormality of the renal tubule	HPO Gene-Disease Associations	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14918
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040402
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.909191
Nephrocalcinosis	DisGeNET Gene-Disease Associations	1.0	null
Nuclear body	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
abnormality of skeletal physiology	HPO Gene-Disease Associations	1.0	null
Hypermanganesemia with dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
FEZ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0050017
FHL2	Pathway Commons Protein-Protein Interactions	1.0	null
Hyperparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.592
CNST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98051
SKMEL3	CCLE Cell Line Gene CNV Profiles	1.0	1.3534
Perturb_10683_OE_hURI_SRP026667	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.96456
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
elevated alkaline phosphatase	HPO Gene-Disease Associations	1.0	null
muscle weakness	MPO Gene-Phenotype Associations	1.0	null
abnormal circulating mineral level	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-3605-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
OVCA420	DepMap CRISPR Gene Dependency	1.0	2.00177
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
BRD-K37544873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2305
BRD-K14470344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.42017
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GSE178714_6_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.23221
Metabolism of proteins	Reactome Pathways 2024	1.0	null
increased urine phosphate level	MPO Gene-Phenotype Associations	1.0	null
Familial juvenile hyperuricemic nephropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	6.43275
HT-29	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MG-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Extracellular ferritin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.737
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041552
BRD-K47707657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43958
Jejunum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.539
CRCGN010_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3105
Brain Lower Grade Glioma_LGG_TCGA-HT-7860-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74581
Diabetes insipidus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
BRD-K23535862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2938
Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T3-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K43473008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3421
Apical plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.076
ETS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2697
rhombomere 9	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09908
currents	GeneRIF Biological Term Annotations	1.0	null
PMC9161725-Table_4.xlsx-EHF-CSAG1_EHF	Rummagene Transcription Factor Associations 2026	1.0	null
odontogenesis	GO Biological Process Annotations 2015	1.0	null
Contractile vacuolar membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.308
BRD-K37459038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3256
duodenum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.243918
BRD-K15373812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13808
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.338545
BRD-K66649343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62374
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.9827
Perturb_15133_OE_Klf10_SRP360603	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A4ZB-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WSU-NHL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6216
autosomal dominant inheritance	HPO Gene-Disease Associations	1.0	null
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20414
GSE180525,GSE180528_1_v_0_tbx3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99833695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08138
Ost-alpha/Ost-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.613
Duodenum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.673
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
characteristics	GeneRIF Biological Term Annotations	1.0	null
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061274
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.78226
BRD-K21466747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66615
GSE138019_1_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dexamethasone_rattus norvegicus_gpl1355_gds3746	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZFP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91196
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U0-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A704	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K07307589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00614
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
Chromosomal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4269881__F6	PFOCR Pathway Figure Associations 2023	1.0	null
Perturb_8043_KO_Zeb2_SRP261907	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.21351
BRD-K61520618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49671
BRD-K37486644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51336
cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K76202128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23531
Fibrous dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.774
heterocycle metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
vesicle	GO Cellular Component Annotations 2015	1.0	null
BRD-K07384081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32004
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0202
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15102
hsa-miR-4425	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.494
transporters	GeneRIF Biological Term Annotations	1.0	null
Episodic ataxia type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
promoter	GeneRIF Biological Term Annotations	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.649
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03399
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table4_gnomAD_EAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
FTC238	CCLE Cell Line Gene CNV Profiles	-1.0	-2.51058
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04574
BRD-K48699175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2496
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20663
GSE175787_4_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6593
pulmonary emphysema	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.33066
EZH2	ENCODE Transcription Factor Targets	1.0	null
chemical homeostasis	GO Biological Process Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3I6-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAV2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00561688
BRD-K46161579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56832
BRD-K02809100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38482
GSE245390_2_v_1_acss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.5003
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	1.65083
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.2779
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PIK3R4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99065
hsa-miR-544b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K03852663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86306
r10 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49707
NCIH650	CCLE Cell Line Gene CNV Profiles	1.0	1.42207
BRD-K14139166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05759
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54774
blood coagulation disease	GWASdb SNP-Disease Associations	1.0	2.06032
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.831894
CRCGN009_HEPG2_24H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.15175
provide	GeneRIF Biological Term Annotations	1.0	null
CRCGN014_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2436
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44211
GRIN2D	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7863-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CMTR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55441
ERVK3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50502
Lumbar spine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.488
PHF20L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40485
LLC-PK1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.997
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
Acne_Sebocyte_GSE10432	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.72691
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A	JASPAR Predicted Transcription Factor Targets	1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9587
Gigantocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15788
hsa-miR-4742-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
bp94	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.657
hsa-miR-4701-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4101
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-6846-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU349	CCLE Cell Line Gene CNV Profiles	1.0	1.82678
abnormal bone ossification	MPO Gene-Phenotype Associations	1.0	null
Perturb_8411_KO_Srsf1_SRP252896	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.5736
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82802
BRD-K12624449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13295
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226439,GSE226441_6_v_2_hnf4g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.497
MEC1	DepMap CRISPR Gene Dependency	1.0	2.47988
ETV5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3549
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17164
U2OS	CCLE Cell Line Gene Expression Profiles	-1.0	-2.27143
BRD-K16686330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3026
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.88422
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42F-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5293
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.35595
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.18527
Prostate adenocarcinoma_PRAD_TCGA-FC-A8O0-01A-41R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
BRD-K42789863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08995
Pinealocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.156
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LIVF001-025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.97292
developmental process	GO Biological Process Annotations 2015	1.0	null
PEX19	Pathway Commons Protein-Protein Interactions	1.0	null
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
syndrome	GeneRIF Biological Term Annotations	1.0	null
PU.1-20513432-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
response to lipid	GO Biological Process Annotations 2015	1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.2915
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.3934
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K27525788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18037
Caudoputamen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23886
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sodium:phosphate symporter activity	GO Molecular Function Annotations 2025	1.0	null
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Ureteric bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.155
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26535
abnormal reproductive system physiology	MPO Gene-Phenotype Associations	1.0	null
parts	GeneRIF Biological Term Annotations	1.0	null
r9 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15261
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05863
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00982
Vitamin D-dependent rickets type 1B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.749
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07495
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
Dhori Virus_48Hour_20090954_GSE17400	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.50073
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.03355
Nephridium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
Nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.911
SUDHL10	CCLE Cell Line Gene Expression Profiles	1.0	1.49768
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.682693
rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.1051
BRD-K28811650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08568
GSE210655_1_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K05699155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.352
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.213471
vesicle	GO Cellular Component Annotations 2025	1.0	null
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K50712773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38884
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02318
specific	GeneRIF Biological Term Annotations	1.0	null
DLG4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K14392329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12103
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.85702
free-living state	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.991
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.30672
BRD-K38403252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0036
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
Lateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49797
NEPHROLITHIASIS/OSTEOPOROSIS, HYPOPHOSPHATEMIC, 1	CTD Gene-Disease Associations	1.0	2.88009
PANC0327	DepMap CRISPR Gene Dependency	1.0	2.64863
Iminoglycinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.47
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.7403
PATU8988T	DepMap CRISPR Gene Dependency	1.0	2.13532
SNUC1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.15241
FOXK2_02_31	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.32193
homeostasis	GeneRIF Biological Term Annotations	1.0	null
BRD-K17482962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74138
IGROV1	BioGPS Cell Line Gene Expression Profiles	1.0	0.835674
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.03267
Ulcerative colitis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
HDQ-P1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3689d	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6516-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.3363
ECC4	DepMap CRISPR Gene Dependency	1.0	3.11214
Prostate adenocarcinoma_PRAD_TCGA-G9-6339-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	68.7
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80O-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HPBALL	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84309
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04674
BRD-K89584810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61052
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.838819
hemochromatosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.454093
BRD-K35288606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22464
Anodontia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
Nephrolithiasis	HuGE Navigator Gene-Phenotype Associations	1.0	null
hypophosphatemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.99872
Inflammation	CTD Gene-Disease Associations	1.0	1.13041
BRD-K38737333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17749
organ development	GO Biological Process Annotations 2015	1.0	null
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.25765
BRD-K32434600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25274
CTCF	ENCODE Transcription Factor Targets	1.0	null
BRD-K18865369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03926
Microtubule cytoskeleton	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.90355
LNCAP	BioGPS Cell Line Gene Expression Profiles	1.0	1.27099
Polyuria	DisGeNET Gene-Phenotype Associations	1.0	null
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.25
BRD-K27597444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81542
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.844211
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.47849
Lung squamous cell carcinoma_LUSC_TCGA-56-8625-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.81325
regulation of phosphate transmembrane transport	GO Biological Process Annotations 2015	1.0	null
seem	GeneRIF Biological Term Annotations	1.0	null
CD7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00495336
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10515843-media-1.xlsx-Table_7_Diff_loop_genes_E_v_S-Supplementary_Table_7_Genes_that_involve_significant_differential_looping_in_pediatric_primary_B_cell_CTCF_peaks_compared_to_GM12878_CTCF_peaks_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07644
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.93377
apical part of cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Osteochondrodysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.518
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Fanconi Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K54549319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16873
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19787
CRCGN008_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.87917
meropenem-7180	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065783
Posterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97565
CRCGN014_HEPG2_24H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.79708
BRD-K45428339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04422
Inositol phosphoceramide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.532
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30647
clinically	GeneRIF Biological Term Annotations	1.0	null
BC-3	GDSC Cell Line Gene Expression Profiles	1.0	1.61587
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal eating behavior	MPO Gene-Phenotype Associations	1.0	null
BRD-K42214389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.4245
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Parathyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.571
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IGR39	DepMap CRISPR Gene Dependency	1.0	2.1862
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8891
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3783
BRD-K42716291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81924
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.75604
ARHGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22357
BRD-K05128360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01924
positive regulation of membrane potential	GO Biological Process Annotations 2015	1.0	null
BRD-K19958830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03801
Osteitis fibrosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.645
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21364
iic	GeneRIF Biological Term Annotations	1.0	null
cell projection membrane	GO Cellular Component Annotations 2023	1.0	null
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.62628
SOX2	ChEA Transcription Factor Targets	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
xenopus	GeneRIF Biological Term Annotations	1.0	null
GSE145639_7_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K95147720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71084
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Posterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20949
Muscular Dystrophy_Muscle - Striated (Skeletal) (MMHCC)_GSE2507	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.68155
GSE157594_3_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
r9 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05983
hsa-miR-4736	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66183
Hip joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
LN464	Achilles Cell Line Gene Essentiality Profiles	1.0	1.07726
RD	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85173
LN235	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.12274
BRD-K29144638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00359
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45013233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35845
Perturb_1736_OE_NHD13_SRP068420	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6MF-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.209
cisplatin_homo sapiens_gpl570_gse23553	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29263
FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0923
NR6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.15296
STAT1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE180575_1_v_0_fmo5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76513704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81546
response to mercury ion	GO Biological Process Annotations 2025	1.0	null
SLR24	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.12697
decreased birth weight	MGI Mouse Phenotype Associations 2023	1.0	null
Sinus node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
496100365_HIP_probable Alzheimer's disease_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47479
response to potassium ion	GO Biological Process Annotations 2015	1.0	null
GSE149264,GSE149267_4_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K17659275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02204
rilmenidine-3133	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878456
Basal ganglia disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.341
cellular nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
all	HPO Gene-Disease Associations	1.0	null
PDZK1-NaPiIIa-MAP17 complex	CORUM Protein Complexes	1.0	null
hsa-miR-4673	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
abnormality of amino acid metabolism	HPO Gene-Disease Associations	1.0	null
membrane raft	GO Cellular Component Annotations 2015	1.0	null
BRD-K59064238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55154
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039931
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Caov-4	GDSC Cell Line Gene Expression Profiles	-1.0	-1.41871
KASUMI1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.15829
Transmembrane transport of small molecules	Reactome Pathways 2014	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.561
Primary somatosensory area, unassigned, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92602
cycle	GeneRIF Biological Term Annotations	1.0	null
Macula densa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.859
MITF	ChEA Transcription Factor Targets	1.0	null
H2AC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41174
496100363_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.54064
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12308
RKN	Achilles Cell Line Gene Essentiality Profiles	1.0	1.02094
STK35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31411
Nephrolithiasis	ClinVar Gene-Phenotype Associations 2025	1.0	null
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.83947
Lung adenocarcinoma_LUAD_TCGA-55-6987-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58568
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07108
bone remodeling	GO Biological Process Annotations 2015	1.0	null
TCF7L2-21901280-H4IIE-RAT	ChEA Transcription Factor Targets 2022	1.0	null
Synaptic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.125
olanzapine_rattus norvegicus_gds2608	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
response to estrogen	GO Biological Process Annotations 2015	1.0	null
hsa-miR-4692	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
brush border	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
growth abnormality	HPO Gene-Disease Associations	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal urine phosphate concentration	HPO Gene-Disease Associations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-M8-A5N4-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Calcium metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.744
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Neck	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.04
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	2.10857
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05266
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.46461
HIV_Infected-mDC_None_GSE42058	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.18721
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.057222
response to drug	GO Biological Process Annotations 2015	1.0	null
BRD-K13970506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29724
Adrenal gland hyperfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
Renal papilla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.981
SLC9A3R1	Pathway Commons Protein-Protein Interactions	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16317
Dental pulp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
voltage	GeneRIF Biological Term Annotations	1.0	null
Anterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.02118
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
biotin-3289	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.15444
NFI-21473784-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TRAPPC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93313
Creatinine Measurement, Serum (Procedure)	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K25426017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08652
Perturb_11199_KD_Scap_SRP311091	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.59779
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EK-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
interleukin-23 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.225622
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02229
whereas	GeneRIF Biological Term Annotations	1.0	null
BRD-K16044155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16141
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60416
Urinary tract obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.555
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.93466
homeostatic process	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-7020-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K40367360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43108
HSP90AB1	Hub Proteins Protein-Protein Interactions	1.0	null
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.338191
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.877247
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	1.0	1.48257
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.27304
oxprenolol-6145	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10084
fibrous dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.470711
DNAJC2-21179169-NT2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K41008930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26577
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30468
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7404
Vitamin D-dependent rickets type 2A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.784
Glomerular endothelium fenestra	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.59
Generalized Aminoaciduria	DisGeNET Gene-Phenotype Associations	1.0	null
ANHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25832
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4C9-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01687
GSK3A_KD_GDS4305_182_human_THP-1 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7797-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70518736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15271
Dental abscess	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.145
Dicarboxylic aminoaciduria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-2.32905
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.122085
hsa-miR-338-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
BRD-K20091931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09333
sirolimus_rattus norvegicus_gpl1355_gse19366	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN009_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23423
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_11112_KO_Gmfb_SRP359344	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.93123
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4476	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
binds	GeneRIF Biological Term Annotations	1.0	null
Periosteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.229
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC0327	CCLE Cell Line Gene CNV Profiles	1.0	1.69261
Primary somatosensory area, lower limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46418
Long bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.476
cohort	GeneRIF Biological Term Annotations	1.0	null
ZBTB48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83607
CAMK2G	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Uranium	CTD Gene-Chemical Interactions	1.0	null
reticulotegmental nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07759
MDA-MB-330	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4969-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.44484
Tuberculosis	DisGeNET Gene-Disease Associations	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15737
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
C32	Achilles Cell Line Gene Essentiality Profiles	1.0	1.51483
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
kidney	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1954	CCLE Cell Line Gene CNV Profiles	1.0	2.26839
ERA-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Fanconi Renotubular Syndrome	DisGeNET Gene-Disease Associations	1.0	null
ACTN2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8040704-jcav12p2673s2.xlsx-Down-regulated_genes_in_EBF1-Unnamed_0_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.63413
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.126
RAD9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27453
SMAD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31057
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Podocyte foot	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.685
abnormal urine phosphate level	MPO Gene-Phenotype Associations	1.0	null
CRCGN014_HEPG2_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16888
cotransporter	GeneRIF Biological Term Annotations	1.0	null
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
HS172T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.766
proton	GeneRIF Biological Term Annotations	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Phagolysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.14
BRD-K36713925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63998
BRD-K30284601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50746
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.84307
hsa-miR-4443	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
BRD-K01639343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42513
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GR-ST	GDSC Cell Line Gene Expression Profiles	-1.0	-1.82265
Lung squamous cell carcinoma_LUSC_TCGA-21-1082-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4283	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
muscle phenotype	MPO Gene-Phenotype Associations	1.0	null
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5545
braf	GeneRIF Biological Term Annotations	1.0	null
BCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49914
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.08325
Primary somatosensory area, mouth, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02746
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29487
YH-13	GDSC Cell Line Gene Expression Profiles	1.0	1.87424
allowed	GeneRIF Biological Term Annotations	1.0	null
BRD-K98095706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05039
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878456
Hyperphosphatemic familial tumoral calcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.787
ZNF30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42077
napiiib	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-3191	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.349
BRD-K04013642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12885
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00006
intracellular part	GO Cellular Component Annotations 2015	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ectorhinal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42928
BRD-K32205799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39689
Brush border	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
ethotoin-4366	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6252
HEC151	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01187
FOXA1-25552417-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Arterial calcification of infancy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.643
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K09454191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4747
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.984228
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.39579
organic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
phosphorus metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.8701
BRD-K19946529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42344
response to organic cyclic compound	GO Biological Process Annotations 2015	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4546
methylprednisolone_rattus norvegicus_gpl85_gds965	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Primary somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37356
496100376_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.24437
r6 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06109
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.907938
NCIH929	CCLE Cell Line Gene Expression Profiles	1.0	1.56135
RMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48836
positive regulation of anion transport	GO Biological Process Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VK-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Connecting tubule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.885
abnormality of the upper urinary tract	GWASdb SNP-Phenotype Associations	1.0	0.366225
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.156513
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SET2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64274
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.03308
skimmianine-2504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
Perturb_10319_KO_Pdk2_SRP216037	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Autosomal dominant polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
SJSA1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.26532
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ureteral obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.431
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19731
SW 982	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1541
reabsorption	GeneRIF Biological Term Annotations	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M4-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.77908
X-linked recessive hypophosphatemic rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.954
SCA7_Knock-in_GDS3545_560_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
LS1034	DepMap CRISPR Gene Dependency	1.0	5.07233
CAS1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.18347
r8 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17768
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.577581
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TC32	CCLE Cell Line Gene Expression Profiles	1.0	1.47411
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70612
sodium:phosphate symporter activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K54456668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05314
BRD-K69482343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16975
phosphate	GeneRIF Biological Term Annotations	1.0	null
nephrolithiasis	GWASdb SNP-Phenotype Associations	1.0	0.804323
oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.15495
Kidney Failure, Chronic	HuGE Navigator Gene-Phenotype Associations	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.33511
other	GeneRIF Biological Term Annotations	1.0	null
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inorganic ion homeostasis	GO Biological Process Annotations 2015	1.0	null
spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.223662
BRD-K94442101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52392
MED12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1988
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42937
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7179
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.836209
COA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0397
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC transporter disorders	Reactome Pathways 2024	1.0	null
Polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.44
cell projection membrane	GO Cellular Component Annotations 2015	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Cortical collecting duct cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
CLEC2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81824
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal protein level	MPO Gene-Phenotype Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RC-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-6845-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CORL279	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34073
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25154
humans	GeneRIF Biological Term Annotations	1.0	null
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878456
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878456
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8S8-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
Stolon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10953
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
kidney	GTEx Tissue Gene Expression Profiles	1.0	2.18987
abnormal survival	MPO Gene-Phenotype Associations	1.0	null
BRD-K50008138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51884
EP300	ENCODE Transcription Factor Targets	1.0	null
cation transport	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8392-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of transmembrane transport	GO Biological Process Annotations 2015	1.0	null
NCIH1105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37482
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7UY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23854
BRD-K33456231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70082
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10178
HNRNPA1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23944
GCT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.999219
TFAP2C	JASPAR Predicted Transcription Factor Targets	1.0	null
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04612
together	GeneRIF Biological Term Annotations	1.0	null
GSE210655_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Anterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3003
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.336
RBBP5	ENCODE Transcription Factor Targets	1.0	null
NPY1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05518
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.836547
CXCR7_Deficiency_GDS3183_604_mouse_Neonatal semilunar valves	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cellular response to staurosporine	GO Biological Process Annotations 2015	1.0	null
BRD-K15879529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71294
Paragigantocellular reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25254
pdz1	GeneRIF Biological Term Annotations	1.0	null
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.34641
abnormal body composition	MPO Gene-Phenotype Associations	1.0	null
tertiary granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.393162
cellular process	GO Biological Process Annotations 2015	1.0	null
response to ammonium ion	GO Biological Process Annotations 2015	1.0	null
SAP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02174
SLC38A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3514
BHT101	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49805
RHOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90131
Hemochromatosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
abnormal birth body size	MPO Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.21785
growthrelated	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5676-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29361
WSU-NHL	GDSC Cell Line Gene Expression Profiles	1.0	2.13987
Temporal association areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76077
understanding	GeneRIF Biological Term Annotations	1.0	null
organism	GeneRIF Biological Term Annotations	1.0	null
BRD-K93337444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16825
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051533
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.926491
Filtration diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.864
entorhinal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09516
BRD-K34747076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43396
Small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.923
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23541
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.837549
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3153
Hypophosphatemic Rickets With Hypercalciuria, Hereditary	DisGeNET Gene-Disease Associations	1.0	null
Sarcoidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
cSARS Bat SRBD_0Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.928134
BRD-K23956044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68401
Basal labyrinth	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.873
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32445732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29564
VCAP	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.66932
BRD-K29560103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75769
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.28585
BRD-K29200961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55698
inner CP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.849809
BRD-K85347477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41381
H3K36me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPS6KA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.254
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30234
Disorders of transmembrane transporters	Reactome Pathways 2024	1.0	null
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.546472
NAPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75783
Kyphosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.52
BRD-K10911459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08054
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.943583
Kidney_CT1_Proximal Tubule Epithelial Cell Segment 2	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
hematopoietic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066151
BRD-K37790543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04433
HSP90AA1	Hub Proteins Protein-Protein Interactions	1.0	null
ZNF880	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38289
layer 2 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54444
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.834597
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12475
experiments	GeneRIF Biological Term Annotations	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30468
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
Pelvis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.902829
decreased body size	MPO Gene-Phenotype Associations	1.0	null
D-283MED	GDSC Cell Line Gene Expression Profiles	-1.0	-1.83742
esophagus	HPA Tissue Protein Expression Profiles	1.0	1.1793
decreased birth weight	MPO Gene-Phenotype Associations	1.0	null
GSE147662_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.069171
Focal segmental glomerulosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
Phosphorus levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.2699
Tetraamelia syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
positive regulation of inorganic anion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
RBPMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8037
fanconi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.475634
kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.791721
Connecting tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.845
BRD-K73562260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70827
BRD-K09227140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56143
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CJ-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vesicle	GO Cellular Component Annotations 2023	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.326
Hyperuricemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5079533__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Thyroid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.136
FOXA1-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K26237438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27877
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06547
TATDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.065
response to lead ion	GO Biological Process Annotations 2025	1.0	null
SLR25	CCLE Cell Line Gene CNV Profiles	1.0	1.88959
RUNX1-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
elevated alkaline phosphatase of bone origin	HPO Gene-Disease Associations	1.0	null
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC70	Achilles Cell Line Gene Essentiality Profiles	1.0	1.28828
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24804
JUND	ENCODE Transcription Factor Targets	1.0	null
Gustatory areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1627
gentamycin metabolic process	GO Biological Process Annotations 2015	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.41918
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.907591
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.16512
Perturb_11108_KO_Cpt2/Ppara_SRP303636	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.2265
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
CAMK2A	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN014_HEPG2_3H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4185
Plasma membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.301
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15901
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_16_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
KARPAS299	CCLE Cell Line Gene Expression Profiles	1.0	1.45118
Ulcerative colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.235
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0195
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17425
nsd1	GeneRIF Biological Term Annotations	1.0	null
response to hormone	GO Biological Process Annotations 2015	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
solute:sodium symporter activity	GO Molecular Function Annotations 2025	1.0	null
ZNF556	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08784
calcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.922149
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.872071
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.753623
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP63_NULL MUTATION_GDS1434_308_mouse_Skin at embryonic age E18.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
positive regulation of phosphate transmembrane transport	GO Biological Process Annotations 2015	1.0	null
BRD-K40292034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11203
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051448
GSE214823,GSE214824_6_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162575,GSE162609_3_v_2_tfe3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044063
Perturb_8417_KO_Srsf1_SRP252896	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.37302
Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Chondrocalcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.048
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A686-06A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.0828
Brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.904
achieves	GeneRIF Biological Term Annotations	1.0	null
positive regulation of sodium-dependent phosphate transport	GO Biological Process Annotations 2015	1.0	null
BRD-K38932508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44938
CRCGN014_HEPG2_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.48053
Sotos syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.467
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08412
ZC3H12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1726
BRD-K16838444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68779
Apical part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.446
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01594
binding	GO Molecular Function Annotations 2015	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31365
single-organism transport	GO Biological Process Annotations 2015	1.0	null
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Fanconi renotubular syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.057
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of anion transport	GO Biological Process Annotations 2015	1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05546
CFPAC-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.46941
CFTR_Deficiency_GDS1843_191_mouse_Lungs - Animals examined at 3 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
handling	GeneRIF Biological Term Annotations	1.0	null
FASTKD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60978
postcentral gyrus, right, inferior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.85274
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29511
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A-Vietnam-1203-2004(H5N1)_2day-TNFRSF1BKO_None_GSE40792	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.96018
Leukemia	DisGeNET Gene-Disease Associations	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nephrogenic diabetes insipidus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9933
KIAA1671	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73023
PMC3296722-pone.0032481.s009.xlsx-Sheet_1_MSC_vs_references-Gene_Symbol_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
macropinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.328708
BRD-K81510336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39253
Distal arthrogryposis type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
macromolecular complex assembly	GO Biological Process Annotations 2015	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39369
hela-s3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283191
H3K27me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
surface	GeneRIF Biological Term Annotations	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-33	GDSC Cell Line Gene Expression Profiles	1.0	1.83903
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal hormone level	MPO Gene-Phenotype Associations	1.0	null
establishment of localization	GO Biological Process Annotations 2015	1.0	null
cellular response to endogenous stimulus	GO Biological Process Annotations 2015	1.0	null
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.06448
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LATS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05902
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22882
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.187
AG-013608-6395	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Surfactant metabolism	Reactome Pathways 2024	1.0	null
layer 3 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04358
muscle weakness	HPO Gene-Disease Associations	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47285393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18662
SNX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56141
Uterine Carcinosarcoma_UCS_TCGA-N8-A56S-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
irinotecan_rattus norvegicus_gpl1355_gds3466	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.268969
Nephrolithiasis/osteoporosis	ClinVar Gene-Phenotype Associations 2025	1.0	null
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	1.1793
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.4463
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62326
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.74627
BRD-K84707727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76082
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08751
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08991
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06898
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63545
oocyte	GeneRIF Biological Term Annotations	1.0	null
BRD-K04680784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18676
kidney	HPA Tissue Gene Expression Profiles	1.0	2.24804
BRD-K50315405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1829
Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4492	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
abnormal motor capabilities/coordination/movement	MPO Gene-Phenotype Associations	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-MEL-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
decreased circulating parathyroid hormone level	MGI Mouse Phenotype Associations 2023	1.0	null
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15396
Cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
medial part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28557
body of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32455
Striatum dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2397
how	GeneRIF Biological Term Annotations	1.0	null
cell projection membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.65509
Inner ear disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
Perturb_10279_KO_Lyplal1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.24322
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
LMO2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0559
MYOD1	ENCODE Transcription Factor Targets	1.0	null
liver	GTEx Tissue Gene Expression Profiles	1.0	1.06381
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86002795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42416
biological_process	GO Biological Process Annotations 2015	1.0	null
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K33274327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02673
CRCGN013_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43109
BRD-K43729445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25676
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tooth enamel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.205
CRCGN017_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26623
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0865
RT112	DepMap CRISPR Gene Dependency	1.0	4.67395
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.14697
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.79484
Lung squamous cell carcinoma_LUSC_TCGA-22-4595-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10085
BRD-K65875972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48553
Renal artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.133
contributes	GeneRIF Biological Term Annotations	1.0	null
BRD-K28522188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69621
tropicamide-2309	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K21119095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00388
Transport of small molecules	Reactome Pathways 2024	1.0	null
Chronic kidney disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.566
Renal osteodystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.861
Primary somatosensory area, unassigned	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23055
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10284009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28008
CRCGN015_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.85497
mantle zone of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22479
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36316
BRD-K18077898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87802
BRD-K51666223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07343
napi	GeneRIF Biological Term Annotations	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.037
Urinary tract infection	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
CRCGN015_MCF10A.WT.HP_24H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.36452
8505C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Primary somatosensory area, lower limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1754
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EA-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85115
SKRC20	CCLE Cell Line Gene Expression Profiles	1.0	1.64232
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059212
H3-7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36212
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.87369
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46125
abnormal renal morphology	GWASdb SNP-Phenotype Associations	1.0	0.286699
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6011-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0877
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FS-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K33734659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3586
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.39113
Hypercalcemia	DisGeNET Gene-Disease Associations	1.0	null
brush border membrane	GO Cellular Component Annotations 2025	1.0	null
BRD-K38084509	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48047
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
rosiglitazone_rattus norvegicus_gpl1355_gds3396	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Waist-to-hip ratio adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.7
MFE-280	GDSC Cell Line Gene Expression Profiles	-1.0	-1.58513
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.32595
osteoporosis	HPO Gene-Disease Associations	1.0	null
Perturb_11054_KO_Mettl3_SRP363782	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.49212
superficial stratum of ERCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09478
De Toni-Debre-Fanconi Syndrome	DisGeNET Gene-Disease Associations	1.0	null
reduced	GeneRIF Biological Term Annotations	1.0	null
RRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.64818
critical	GeneRIF Biological Term Annotations	1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Creatinine levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_10903_KO_Ppp1r3c_SRP019798	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.28021
MT-CO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65857
Nephrolithiasis/osteoporosis, hypophosphatemic, 1	ClinVar Gene-Phenotype Associations	1.0	null
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.974116
BRD-K64356525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59509
PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11876052-DataSheet2.xlsx-Endo2-GATA3_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.172334
hypochromic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.879424
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SP-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r8 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.33052
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.104267
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.79688
decreased circulating phosphate level	MPO Gene-Phenotype Associations	1.0	null
BRD-K37379978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33886
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.1228
Subapical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.28
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.31669
SRCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54436
NCIH747	DepMap CRISPR Gene Dependency	1.0	2.61177
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79284
Prostate adenocarcinoma_PRAD_TCGA-CH-5768-11A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.06198
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.859392
BRD-K09144377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75819
STK25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79896
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4643	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
MYO18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34277
abnormal renal physiology	HPO Gene-Disease Associations	1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8118
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.5016
hsa-miR-3202	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K74701308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49757
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59601
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.4634
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.958678
response to metal ion	GO Biological Process Annotations 2015	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.671285
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, unassigned, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.49745
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4851
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_206_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K57084585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.50449
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.519798
decreased birth body size	MPO Gene-Phenotype Associations	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r10 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19622
GSE235234_2_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3X2-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Parathyroid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.594
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178560_0_v_1_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.5186
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.94414
Renal proximal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.121
MCF7	CCLE Cell Line Gene Expression Profiles	1.0	1.70517
TP63	ChEA Transcription Factor Targets	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
NCIH1105	CCLE Cell Line Gene Expression Profiles	-1.0	-2.66642
Urinary electrolytes (magnesium/calcium ratio)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.822185
PMC6073502__F4a	PFOCR Pathway Figure Associations 2024	1.0	null
DCANP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13289
brush border membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
organonitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K29468949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21079
r8 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32429
AR-22383394-PROSTATE-CANCER-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
odontogenesis of dentin-containing tooth	GO Biological Process Annotations 2015	1.0	null
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.53
BRD-K44363090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66559
Calcium oxalate nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
CD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.946
GATA3-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42695
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052436
mitotic spindle	GO Cellular Component Annotations 2023	1.0	null
hsa-miR-3944-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57758
AKT1_knockdown_43_GSE12291	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.80449
FEV	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3535
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
layer 4 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02142
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67801
BRD-K76701247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39551
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.74009
Failure To Thrive	DisGeNET Gene-Disease Associations	1.0	null
PCI-6A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.894484
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08131
HEK 293 T-rex    	BioGPS Cell Line Gene Expression Profiles	1.0	1.08147
ion homeostasis	GO Biological Process Annotations 2015	1.0	null
Mesangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.357
Fanconi-Bickel Syndrome	DisGeNET Gene-Disease Associations	1.0	null
carboxylic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.906
BRD-K26689527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.69171
BRD-K16976282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38678
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
cellular response to nitrogen compound	GO Biological Process Annotations 2015	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.3522
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	2.30386
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.22246
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K95863777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8591
U343	CCLE Cell Line Gene Expression Profiles	1.0	1.42325
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30914
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.00752
Contractile vacuole complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.16
BRD-K08107521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3428
abnormal circulating protein level	MPO Gene-Phenotype Associations	1.0	null
BRD-K44225498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22483
SPAG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46281
Perturb_10282_KO_Phpt1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.7747
Familial hypocalciuric hypercalcemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.682
Inflammatory bowel disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.778
Glomerular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.848
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80013
E2F6	ENCODE Transcription Factor Targets	1.0	null
abnormality of urine calcium concentration	HPO Gene-Disease Associations	1.0	null
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061488
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
BRD-K56179613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31642
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7124
Potassium	CTD Gene-Chemical Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TZ-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
GSE190534,GSE190536_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
response to chemical	GO Biological Process Annotations 2015	1.0	null
Bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.176
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055589
ZR-75-30	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51579
CRCGN017_MCF10A.WT.HP_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03824
abnormal urine calcium level	MPO Gene-Phenotype Associations	1.0	null
PRR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4966
picrotoxinin-4260	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
large	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.27271
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7857731-elife-63093-supp5.xlsx-ECMdegs-MITF-X6_vs_EVSkMel28-Unnamed_36_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
parathyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.118357
Bartter disease type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
bone marrow	HPA Tissue Protein Expression Profiles	1.0	1.1793
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A43Y-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K12836153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41459
SKMM2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.28305
cebplike	GeneRIF Biological Term Annotations	1.0	null
response to mercury ion	GO Biological Process Annotations 2015	1.0	null
Fatty acid elongase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.681
increased circulating calcium level	MGI Mouse Phenotype Associations 2023	1.0	null
TMEM143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05978
BRD-K28057105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09023
cellular component assembly	GO Biological Process Annotations 2015	1.0	null
PMC6995218-12864_2020_6525_MOESM3_ESM.xlsx-D2FAST48h_vs_D3REFED24h_1198_AR-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Hypercalcemia	DisGeNET Gene-Phenotype Associations	1.0	null
ZNF385A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74204
BRD-K66463856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36385
ATCAY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25933
Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6084392-oncotarget-09-30253-s006.xls-geneset2-TF-miRNA-net-GFI1_GFI1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K45717258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26136
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.64308
intermediate stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23748
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.26691
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.241716
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
abnormal circulating calcium level	MPO Gene-Phenotype Associations	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Brn3a_KO_GDS1651_248_mouse_Embryonic (day 13.5) trigeminal ganglia - homozygous	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5691-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CORL51	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45573
mccune albright syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.401572
positive regulation of transport	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6960-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phosphate ion transport	GO Biological Process Annotations 2015	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Potassium Deficiency	DisGeNET Gene-Disease Associations	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.064465
ABHD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44663
BRD-K03606830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45486
chronic renal failure; kidney failure, chronic	GAD Gene-Disease Associations	1.0	null
Primary somatosensory area, upper limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22397
BRD-K03995743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81207
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW954	DepMap CRISPR Gene Dependency	1.0	2.20614
Enamel organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.886
subset	GeneRIF Biological Term Annotations	1.0	null
Osteocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.434
Red Blood Cell Count Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
PMC6073502__F4a	PFOCR Pathway Figure Associations 2023	1.0	null
HS936T	DepMap CRISPR Gene Dependency	1.0	3.54585
Collecting duct cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
intracellular phosphate ion homeostasis	GO Biological Process Annotations 2025	1.0	null
NANOG-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K33805386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37612
Synaptonemal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.777
mode of inheritance	HPO Gene-Disease Associations	1.0	null
BRD-K53443165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65368
CRCGN013_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11894
CORL279	DepMap CRISPR Gene Dependency	1.0	2.44344
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
BRD-K27373956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2944
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8071-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypophosphatemia	DisGeNET Gene-Phenotype Associations	1.0	null
OV-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
response to nitrogen compound	GO Biological Process Annotations 2015	1.0	null
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1374
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.54275
BRD-K40251180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2211
RTL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12712
abnormal glucose homeostasis	HPO Gene-Disease Associations	1.0	null
CDCA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87035
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.56467
Perturb_11290_KO_Bmal1_SRP153814	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.74418
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ectorhinal area/Layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28615
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
homozygous	GeneRIF Biological Term Annotations	1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.4104
lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.070838
abnormal ion homeostasis	MPO Gene-Phenotype Associations	1.0	null
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64303
BRD-K76329122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00406
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17425
BRD-K56562541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19993
transport	GeneRIF Biological Term Annotations	1.0	null
Primary somatosensory area, unassigned, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01896
CHD2	ENCODE Transcription Factor Targets	1.0	null
brush border	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.51074
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.184817
Spinal nucleus of the trigeminal, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54154
BRD-K44371786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0215
SMPDL3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8931
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MU-A5YI-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypoparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.915
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.136885
Choanomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
MIR140_OE_GDS3461_575_mouse_C3H10T1/2 fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K91239327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15461
abnormality of divalent inorganic cation homeostasis	HPO Gene-Disease Associations	1.0	null
496100414_TCx_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.26577
SMC3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE145639_7_v_4_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
abnormal fertility/fecundity	MPO Gene-Phenotype Associations	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878456
YY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25131
Glomerulonephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.473
Vitamin D-Dependent Rickets	DisGeNET Gene-Disease Associations	1.0	null
plasma membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.007697
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13859
BRD-K38073091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43991
ficolin-1-rich granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.894
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47183
r10 part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28201
BRD-K37830990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89116
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF536	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21859
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00619
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Breast Cancer_Mammary Gland Tissue_GSE3744	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.5968
Hypercalcemia	CTD Gene-Disease Associations	1.0	2.88009
Perturb_18151_KO_Cdk1_SRP287303	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.68592
lateral amygdaloid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64664
Hydronephrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.02486
Renal glomerulus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.018
hsa-miR-1912	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13701
cuneus, right, peristriate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.5221
regulation of inorganic anion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
r9 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60311
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.84172
zfpm2_19411579_heart_lof_mouse_gpl1261_gds3659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.016559
BRD-K97746859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58211
r9 portion of vagal motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77968
Hypothyroidism	DisGeNET Gene-Disease Associations	1.0	null
Renal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.096
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HF-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parathyroid	GeneRIF Biological Term Annotations	1.0	null
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30468
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.80575
ZNF653	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41953
endocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.476429
rhombomere 10	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03591
496100563_PCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.28087
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31861
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4451	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
INA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.774
transporter activity	GO Molecular Function Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6982-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_6_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r9 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50277
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79809
pedigrees	GeneRIF Biological Term Annotations	1.0	null
BRD-K26748243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05059
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44956
GSE112860_5_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal lipid homeostasis	MPO Gene-Phenotype Associations	1.0	null
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Throat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.093
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11203_KO_Mettl3_SRP322470	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.47188
disruption	GeneRIF Biological Term Annotations	1.0	null
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23941
OCUB-M	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53034
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.88648
U118MG	DepMap CRISPR Gene Dependency	1.0	7.50828
Mulchandani-Bhoj-Conlin syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
HPCAL1	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A59Z-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.1787
metabolic process	GO Biological Process Annotations 2015	1.0	null
decreased circulating parathyroid hormone level	MPO Gene-Phenotype Associations	1.0	null
Pulmonary emphysema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.273
urinary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.02486
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0305
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.850981
cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060924
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4071
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.998329
Acidosis	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K19652287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75302
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Choroid plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.457
Decreased total lymphocyte count	ClinVar Gene-Phenotype Associations 2025	1.0	null
TYK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97006
symporter activity	GO Molecular Function Annotations 2015	1.0	null
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21446
ion transport	GO Biological Process Annotations 2015	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8427
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.00062
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.31765
phosphate ion homeostasis	GO Biological Process Annotations 2023	1.0	null
plasma	GeneRIF Biological Term Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23478
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.849035
DUSP1_Deficiency_GDS1606_765_mouse_Spleen	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K06743908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49701
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1059
HEC50B	CCLE Cell Line Gene CNV Profiles	1.0	1.99023
BRD-K45272675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87599
TMEM158	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01151
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41612
connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.086717
form	GeneRIF Biological Term Annotations	1.0	null
SW1783	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.29276
PMC6688518-medscimonit-25-5700.nxml--SOX6_SOX6	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.977316
abundance	GeneRIF Biological Term Annotations	1.0	null
abnormality of ion homeostasis	HPO Gene-Disease Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20U-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.01681
CRCGN015_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55052
leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069455
Acute Myeloid Leukemia_LAML_TCGA-AB-2898-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69548
Ureteral disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.81
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.87023
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71883
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0855
response to alcohol	GO Biological Process Annotations 2015	1.0	null
BRD-K93866368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66661
precentral gyrus, right, inferior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38268
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nephron epithelial cell_Kidney_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE158197_2_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8755441-mmc3.xlsx-IRF7-Up-Symbol_1_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
HNF4A	ChEA Transcription Factor Targets	1.0	null
AIF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74301
mantle zone of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14422
Linear nevus sebaceous syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.57
Osteoarthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
MALME 3M	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K56384677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1739
Reticulate body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
PMC11511846-42003_2024_7078_MOESM3_ESM.xlsx-ST18-Unnamed_19_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
Gill	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.028
linkers	GeneRIF Biological Term Annotations	1.0	null
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43422
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8992
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78719595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25331
renal/urinary system phenotype	MPO Gene-Phenotype Associations	1.0	null
Brush border	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.836
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9412
organic cyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914276
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.969366
HCC2814	CCLE Cell Line Gene Expression Profiles	1.0	1.52675
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
osteomalacia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.21652
abnormal postnatal growth/weight/body size	MPO Gene-Phenotype Associations	1.0	null
phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068291
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22574
RCOR1-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Myosin IV complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.533
D423MG	DepMap CRISPR Gene Dependency	1.0	2.07807
Renal glomerular capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.871
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.1633
CRCGN014_HEPG2_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02501
Primary somatosensory area, barrel field	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44588
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
hematopoietic stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062755
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular response to organic substance	GO Biological Process Annotations 2015	1.0	null
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Osteoglophonic dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.753
Cytoplasmic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.675
BRD-K50300854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39995
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K58005972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05915
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.52435
BRD-K81665173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0475
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_14_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.25415
CatSper complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.767
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.837107
PNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.28566
LXR-22292898-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-A79884839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14793
BRD-K06619604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09745
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.4988
genetic	GeneRIF Biological Term Annotations	1.0	null
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_24Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.36322
Cystinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.08
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.01049
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.34372
NEURL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86636
Activated Partial Thromboplastin Time Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
Juxtaglomerular apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.923
HSP90AA1	Pathway Commons Protein-Protein Interactions	1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.894379
Glomerular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.808
mantle zone of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28557
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K61439686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13955
inner CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09286
hsa-miR-4268	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4178
PMC5216924-oncotarget-07-47061-s002.xlsx-Blatt1-LPS_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6356-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K25952063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41528
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Proximal Tubulopathy	DisGeNET Gene-Phenotype Associations	1.0	null
TemporalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.888228
Alport syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JNK_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
response to alkaloid	GO Biological Process Annotations 2015	1.0	null
periventricular stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79809
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transporter	GeneRIF Biological Term Annotations	1.0	null
BRD-K32037893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19431
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WV-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dent disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.553
outer CP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02652
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46608
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
HCC1419	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.14701
metal metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.26124
nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.26734
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830182
BRD-K30933750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43305
BRD-K22748970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18358
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
response to organonitrogen compound	GO Biological Process Annotations 2015	1.0	null
r8 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55099
lateral orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.864162
abnormal enzyme/ coenzyme level	MPO Gene-Phenotype Associations	1.0	null
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
lytic vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.25547
BRD-K96448434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29137
hsa-miR-588	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BL70	CCLE Cell Line Gene Expression Profiles	1.0	1.83028
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06699
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41O-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.977316
Basal part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.1
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.979572
PAFAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82456
BRD-K26079895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71214
r9 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23681
BB30-HNC	GDSC Cell Line Gene Expression Profiles	-1.0	-2.45527
Perturb_10283_KO_Selenbp1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.28079
icSARS CoV_7Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.17526
Perturb_10320_KO_HDAC1/HDAC2_SRP255858	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.03597
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VG-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, nose	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17665
PANC-03-27	GDSC Cell Line Gene Expression Profiles	-1.0	-1.55193
directly	GeneRIF Biological Term Annotations	1.0	null
JHH1	DepMap CRISPR Gene Dependency	1.0	2.13425
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9744938-DataSheet1.PDF-1-ZHX2_ZHX2	Rummagene Transcription Factor Associations 2026	1.0	null
urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CRCGN017_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6919
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.408
Primary somatosensory area, upper limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84049
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE157594_3_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Osteoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.084
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.900997
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Cluster of actin-based cell projections	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
CRCGN017_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.52212
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE181821_1_v_3_mov10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81841
dependency	GeneRIF Biological Term Annotations	1.0	null
macrophage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.243294
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.536
Fanconi Syndrome	CTD Gene-Disease Associations	1.0	2.88009
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
evidence	GeneRIF Biological Term Annotations	1.0	null
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.991641
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58133
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17021
CAMA1	DepMap CRISPR Gene Dependency	1.0	6.84122
GSE137914_4_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Inflammatory bowel disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
Posterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15118
BRD-K16754572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41457
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040241
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.927932
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
GSE244072_10_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LC1SQSF	CCLE Cell Line Gene CNV Profiles	1.0	1.8285
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6962-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22047
BRD-K46348476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10305
BRD-K28531276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6679
nephrolithiasis	GWASdb SNP-Disease Associations	1.0	0.914528
Hypophosphatemic nephrolithiasis/osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.459
superior temporal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.970225
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
polyol metabolic process	GO Biological Process Annotations 2015	1.0	null
LXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A8-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884973
Craniosynostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
BRD-K43834805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67555
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.80563
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.140478
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.41066
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.77306
Vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.77
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
response to transition metal nanoparticle	GO Biological Process Annotations 2015	1.0	null
ACO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00725
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Cell projection membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
BRD-K29842194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94769
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.34537
response to mercury ion	GO Biological Process Annotations 2023	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.872
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
affinities	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4477b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE144838_7_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bone deterioration disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
caudate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11441
BRD-K42654859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12334
BRD-K44492160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7856
obstructive lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.089042
SUDHL8	DepMap CRISPR Gene Dependency	1.0	3.56456
CRCGN015_HEPG2_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.25083
Primary somatosensory area, lower limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17787
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HQ-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of carboxylic acid metabolism	HPO Gene-Disease Associations	1.0	null
hsa-miR-492	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
abnormal circulating alkaline phosphatase level	MPO Gene-Phenotype Associations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4939
MalFGK2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.684
periventricular stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11225
Apical plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
DARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59513
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
methylprednisolone_rattus norvegicus_gpl341_gds964	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
imatinib_homo sapiens_gpl96_gds3049	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
periventricular stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77669
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.225
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1585
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.03382
RFX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77621
OCILY3	CCLE Cell Line Gene Expression Profiles	1.0	1.43085
Henles loop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.174
PMC8596853-41586_2021_4103_MOESM4_ESM.xlsx-ST18-Unnamed_5_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
Parathyroid hormone synthesis, secretion and action	KEGG Pathways 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AV-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEFL	Pathway Commons Protein-Protein Interactions	1.0	null
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.862256
kidney disease	GWASdb SNP-Disease Associations	1.0	1.29372
rare	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30468
putamen, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45253
abnormal fat-soluble vitamin level	MPO Gene-Phenotype Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J9-A52C-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCCSUP	CCLE Cell Line Gene Expression Profiles	-1.0	-2.24655
mitotic spindle	GO Cellular Component Annotations 2025	1.0	null
abnormality of urine glucose concentration	HPO Gene-Disease Associations	1.0	null
hsa-miR-4771	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AEBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82601
Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4254	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.52671
olanzapine_rattus norvegicus_gpl1355_gds2608	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K67096761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36167
parietal cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22566
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02336
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39402
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney failure	GWASdb SNP-Disease Associations	1.0	0.871531
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6030-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Plasma membrane bounded cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BRD-K52842821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82994
brush border membrane	GO Cellular Component Annotations 2015	1.0	null
ZNF511	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66951
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.03107
Plasma membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ZNF587	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0891
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB436	CCLE Cell Line Gene CNV Profiles	1.0	1.59741
hsa-miR-1207-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.66962
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Idiopathic juvenile osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0305
SLC15A4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00552206
X-linked dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.011
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02872
layer 4 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53493
TGFBR2_knockout_292_GSE46150	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.39705
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.40348
RCOR1	ENCODE Transcription Factor Targets	1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the skeletal system	HPO Gene-Disease Associations	1.0	null
localization	GO Biological Process Annotations 2015	1.0	null
BRD-K23628938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04786
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6333-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.86293
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67689282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53898
HCC1954	DepMap CRISPR Gene Dependency	1.0	2.04404
NB13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Hemorrhage	CTD Gene-Disease Associations	1.0	1.1529
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9466
Calyx	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.821
PER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52683
abnormality of coagulation	GWASdb SNP-Phenotype Associations	1.0	2.02598
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.14605
Familial hypophosphataemic rickets_Renal Tissue_GSE868	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.29645
cellular response to ammonium ion	GO Biological Process Annotations 2015	1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.931298
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Symbiosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.543
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1443
BRD-K68497273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84994
hsa-miR-3661	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.32586
hsa-miR-1912	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Lung adenocarcinoma_LUAD_TCGA-95-8494-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
OV7	DepMap CRISPR Gene Dependency	1.0	8.53757
sodium-dependent phosphate transport	GO Biological Process Annotations 2025	1.0	null
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.1579
H3K27me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	1.0	4.19111
response to inorganic substance	GO Biological Process Annotations 2015	1.0	null
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.842793
response to endogenous stimulus	GO Biological Process Annotations 2015	1.0	null
periventricular stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28411
hypercalciuria	GeneRIF Biological Term Annotations	1.0	null
increased circulating calcium level	MPO Gene-Phenotype Associations	1.0	null
BRD-K39491844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05219
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.22831
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIN7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.621
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7397
MAST2	Pathway Commons Protein-Protein Interactions	1.0	null
sodium ion transport	GO Biological Process Annotations 2023	1.0	null
GSE138019_3_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.994
hsa-miR-4514	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
BRD-K10398797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48305
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.788033
duodenum cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.474119
Renal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.734
CRCGN013_HEPG2_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0762
protein homooligomerization	GO Biological Process Annotations 2015	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCCSUP	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.14324
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.49648
disease	GWASdb SNP-Disease Associations	1.0	0.086244
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.2143
PMC7825356-8844261.f3.docx-32-ZNF284_ZNF284	Rummagene Transcription Factor Associations 2026	1.0	null
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.778
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4784
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17047
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.52671
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Osteogenic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.207
NANOGNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45501
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60502
plasma membrane region	GO Cellular Component Annotations 2015	1.0	null
PTRH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43592
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.753623
intracellular phosphate ion homeostasis	GO Biological Process Annotations 2023	1.0	null
SKNFI	CCLE Cell Line Gene CNV Profiles	-1.0	-2.87538
YIF1A	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HN-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE244072_10_v_3_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Chronic kidney disease	GWAS Catalog SNP-Phenotype Associations	1.0	0.817441
ITK_defectivemutant_125_GSE28200	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.10515
Medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.158
16651409-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.006776
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r10 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38441
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
abnormal vitamin d level	MPO Gene-Phenotype Associations	1.0	null
Autoimmune disease of gastrointestinal tract	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.235
Spindle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
response to nutrient	GO Biological Process Annotations 2015	1.0	null
Vascular Calcification	DisGeNET Gene-Phenotype Associations	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_32_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.1793
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A3-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3454
LOUCY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97023
contiguous	GeneRIF Biological Term Annotations	1.0	null
Perturb_10926_KO_Lis1_SRP126777	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-19.699
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Podocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.833
TMEM267	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29147
DAPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43076
BRD-K36883526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16736
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
apical plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Hypophosphatemia	CTD Gene-Disease Associations	1.0	2.88009
Proximal tubular cell_Kidney_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
fludroxycortide-7378	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYK_knockdown_279_GDS3609	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.38418
Proximal tubule transport	WikiPathways Pathways 2024	1.0	null
cellular response to parathyroid hormone stimulus	GO Biological Process Annotations 2015	1.0	null
BRD-K51207618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24631
Callus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.974
Osteoclast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.67
Small intestine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.546
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.982212
BRD-K04544693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18176
BRD-K08241590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05921
Adrenal gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
Medullary Nephrocalcinosis	DisGeNET Gene-Disease Associations	1.0	null
ERF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0873
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5248-01A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.09094
hsa-miR-330-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.197
OVCAR4	CCLE Cell Line Gene CNV Profiles	1.0	1.43457
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Muscle Weakness	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K44779507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56607
BRD-K62707745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07265
BRD-K76617730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27195
electroneutral	GeneRIF Biological Term Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCTD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70334
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68435627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5896
RUNX1	ChEA Transcription Factor Targets	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gustatory areas, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17416
BRD-K64593260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33567
CRCGN014_HEPG2_3H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1492
OCIMY7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42915
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Microsporidian	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.548
Actin filament bundle of actin-based cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.568
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inner medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
inner CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40574
RAD21_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ISL1-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-3918-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ae2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.818
Inorganic Phosphate Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
Femur	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.612
Hypomagnesemia	DisGeNET Gene-Phenotype Associations	1.0	null
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
abnormal calcium ion homeostasis	MPO Gene-Phenotype Associations	1.0	null
Perturb_10270_KO_Camk2d_SRP281889	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.83973
ZNF814	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30862
BRD-K41206520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39539
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.651026
PFKL_OE_GDS1980_203_mouse_dermal fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
somatic embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.603295
nacoupled	GeneRIF Biological Term Annotations	1.0	null
Renal distal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.61
spindle	GO Cellular Component Annotations 2025	1.0	null
SLC-mediated transmembrane transport	Reactome Pathways 2024	1.0	null
CH157MN	CCLE Cell Line Gene Expression Profiles	1.0	2.01886
Hypoglossal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43811
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893293
Primary somatosensory area, unassigned, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0925
CXXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30564
first	GeneRIF Biological Term Annotations	1.0	null
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
response to peptide hormone	GO Biological Process Annotations 2015	1.0	null
GRIN2C	Pathway Commons Protein-Protein Interactions	1.0	null
Activated partial thromboplastin time	GWAS Catalog SNP-Phenotype Associations 2025	1.0	8.72219
KRBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80612
NCI-H1623	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hypophosphatemia	GeneRIF Biological Term Annotations	1.0	null
Malignant Glioma	DisGeNET Gene-Disease Associations	1.0	null
r4 part of medial paralemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50112
SYK_druginhibition_152_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.29611
BRD-K07781811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02908
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.58931
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
BRD-K42899395	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16119
HUTU80	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.00098
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.67
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K23164928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53734
Type III protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.838
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.990881
CRCGN008_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.46895
Nephrolithiasis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.037
primary visual cortex (striate cortex, area V1/17)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23722
CRCGN012_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04837
Vertebra	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.299
fanconi renotubular syndrome 2	OMIM Gene-Disease Associations	1.0	null
Blount's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
Primary somatosensory area, barrel field, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46191
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.88785
CAV3_Deficiency_GDS3552_558_mouse_Hearts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Rectum adenocarcinoma_READ_TCGA-EF-5830-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5K4-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A641-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Enthesopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.038
NOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42354
Lung adenocarcinoma_LUAD_TCGA-L9-A443-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mononuclear phagocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074154
GSE163275_1_v_0_irf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-7696-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Williams-Beuren syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.438
CAL851	CCLE Cell Line Gene Expression Profiles	-1.0	-2.14619
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.149
BRD-K93993174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09723
Hypercalciuria	DisGeNET Gene-Phenotype Associations	1.0	null
protein oligomerization	GO Biological Process Annotations 2015	1.0	null
cell projection part	GO Cellular Component Annotations 2015	1.0	null
OVSAHO	CCLE Cell Line Gene CNV Profiles	1.0	1.54419
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33745
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein homodimerization activity	GO Molecular Function Annotations 2015	1.0	null
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.58141
Phosphate Diabetes	DisGeNET Gene-Disease Associations	1.0	null
Estimated glomerular filtration rate in non-diabetics	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.6699
BRD-K23393992	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33008
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2682
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81V-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40384
tricarboxylic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
basolateral amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16637
CRCGN016_MCF10A.WT.HP_24H:O09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09145
MC3T3-E1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.21
Cheek pouch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.236
REEP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39916
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.58705
BRD-K82105033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23054
Lung adenocarcinoma_LUAD_TCGA-MP-A4SY-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RABAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03396
CRCGN008_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1029
BRD-K23503923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2721
BRD-K22246901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02364
Hairy root	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.538
organic hydroxy compound metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K21955645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29781
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17933
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055668
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MJ-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
Waist-to-hip ratio adjusted for BMI x sex x age interaction (4df test)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
cell surface	GO Cellular Component Annotations 2015	1.0	null
CXCR6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0046289
INSIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95879
ASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55131
abnormal homeostasis	MPO Gene-Phenotype Associations	1.0	null
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.57635
Phosphorus Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
strychnine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14032
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.18355
contractile vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.35899
BRD-K86349956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17711
response to vitamin	GO Biological Process Annotations 2015	1.0	null
Entorhinal area, lateral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19692
BRD-K67905771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00768
FBXW9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64366
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28689
Microvillar actin bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.576
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74647
McCune Albright syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.051
Lung squamous cell carcinoma_LUSC_TCGA-77-8154-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-635	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
generalized aminoaciduria	HPO Gene-Disease Associations	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40495
Bacteroid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.239
BRD-K20271299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09736
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23131
SMAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92081
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.151
Kidney hypertrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.31
glycosyl compound metabolic process	GO Biological Process Annotations 2015	1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
Intercalated cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.962
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5636
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27726
secretory granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.085695
increased urine calcium level	MPO Gene-Phenotype Associations	1.0	null
Nuclear speck	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Nephrocalcinosis	ClinVar Gene-Phenotype Associations 2025	1.0	null
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
H2369	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HARA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A3KAW	DepMap CRISPR Gene Dependency	1.0	2.10435
Renal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.808
8MGBA	CCLE Cell Line Gene CNV Profiles	1.0	1.50824
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
secondary active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.9416
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5402-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4498	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
increased circulating alkaline phosphatase level	MPO Gene-Phenotype Associations	1.0	null
BRD-K43495666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14761
GATA3-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Abdominal aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.804
vagina	HPA Tissue Protein Expression Profiles	1.0	1.1793
abnormality of the musculature	HPO Gene-Disease Associations	1.0	null
Phimosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
Adenine phosphoribosyltransferase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
cell projection part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.828855
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.925834
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052335
cellular aromatic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100383_HIP_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12546
ZBTB21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40322
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal body size	MPO Gene-Phenotype Associations	1.0	null
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076131
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4278286__F4	PFOCR Pathway Figure Associations 2023	1.0	null
dorsal endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47347
BRD-K35943892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31675
SARS-CoV NSP16_Day7_None_GSE49263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.7188
hairy cell leukemia cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.534251
Primary somatosensory area, trunk, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58508
GSE203060_0_v_1_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.95592
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6228-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51047687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72117
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_31_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.56045
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.84172
monoatomic anion transport	GO Biological Process Annotations 2023	1.0	null
Pup	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.275
BRD-K23342427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07527
BRD-K32965188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00422
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2207
GSE158197_6_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Choroid plexus epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.615
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Metabolic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.753
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.500398
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81T-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal locomotor behavior	MPO Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A70Y-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1224-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
PMC4278286__F4	PFOCR Pathway Figure Associations 2024	1.0	null
NCIH1436	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12224
OVCAR4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51867
CEBPB-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN016_MCF10A.WT.HP_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05493
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.62085
Renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.006
dexamethasone_rattus norvegicus_gpl85_gse6216	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-37-3783-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
indirectly	GeneRIF Biological Term Annotations	1.0	null
Mesangial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.223
response to lead ion	GO Biological Process Annotations 2023	1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metal ion transport	GO Biological Process Annotations 2023	1.0	null
Tooth germ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.054
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.32294
CLIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06341
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100331_TCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.20342
kidney disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.02486
Methane monooxygenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.136
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YC-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HEL9217	DepMap CRISPR Gene Dependency	1.0	2.63271
Renal proximal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.061
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38929571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83059
decreased total tissue mass	MPO Gene-Phenotype Associations	1.0	null
ossification	GO Biological Process Annotations 2015	1.0	null
hsa-miR-4747-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
697	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.14672
BRD-K72083510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53372
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27898
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1675
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82874
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.852484
Perturb_15759_KO_Msi1_SRP353788	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.03202
CITED2_02_38	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.70044
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51209
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of alkaline phosphatase activity	HPO Gene-Disease Associations	1.0	null
PMC9387164-Table_2.XLSX-Sheet1-CLOCK_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
ATPase dependent transmembrane transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.006
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.798
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal circulating parathyroid hormone level	MPO Gene-Phenotype Associations	1.0	null
PAT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.751
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T6-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.235
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
PURB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30323
ASNSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66937
RAD21	ENCODE Transcription Factor Targets	1.0	null
abnormal vitamin D level	MGI Mouse Phenotype Associations 2023	1.0	null
small intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.410909
abnormal urinary electrolyte concentration	HPO Gene-Disease Associations	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
kidney development	GO Biological Process Annotations 2015	1.0	null
GRIN2A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81N-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B2-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE202933_1_v_0_ugt2b28_human	RummaGEO Gene Perturbation Signatures	1.0	null
SKRC20	DepMap CRISPR Gene Dependency	1.0	6.92903
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62275
Temporal association areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3665
abnormal renal/urinary system physiology	MPO Gene-Phenotype Associations	1.0	null
hormone	GeneRIF Biological Term Annotations	1.0	null
tissue remodeling	GO Biological Process Annotations 2015	1.0	null
RARB-27405468-CHIP-SEQ-BRAIN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Primary somatosensory area, upper limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14799
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28089
Pseudohypoparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.466
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.211942
Sodium-coupled phosphate cotransporters	Reactome Pathways 2014	1.0	null
BRD-K60837711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42283
BL70	DepMap CRISPR Gene Dependency	1.0	8.32409
Large latent transforming growth factor-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.538
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054211
CRCGN011_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07355
aminoaciduria	HPO Gene-Disease Associations	1.0	null
BRD-K59046641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19893
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.93953
UBE2R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36596
Colitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.235
decreased body weight	MGI Mouse Phenotype Associations 2023	1.0	null
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fraser syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE239844_1_v_12_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	1.02486
SOX2-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25159
vascular disease	GWASdb SNP-Disease Associations	1.0	0.287801
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.2333
Autosomal dominant hypocalcemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.531
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31834
Somatic embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.87
SNU520	CCLE Cell Line Gene Expression Profiles	1.0	2.66366
OCIMY7	DepMap CRISPR Gene Dependency	1.0	4.3915
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.4492
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.20145
r9 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47008
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.89097
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CMK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
putamen, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.74061
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.922
CCLFPEDS0003T	DepMap CRISPR Gene Dependency	1.0	4.70755
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.52671
HCT116	CCLE Cell Line Gene Expression Profiles	1.0	1.66027
contribute	GeneRIF Biological Term Annotations	1.0	null
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64303
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.991605
17210682-Table2b	GeneSigDB Published Gene Signatures	1.0	null
End stage renal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.107
Reperfusion Injury	DisGeNET Gene-Disease Associations	1.0	null
cellular response to metal ion	GO Biological Process Annotations 2015	1.0	null
NET1_KD_GDS4196_436_human_AGS - gastric adenocarcinoma cells - (63 shRNA Knock-Down)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TBX2-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154767_1_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.298
Phosphorus metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.296
Familial isolated hypoparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.345
16397240-Table1a	GeneSigDB Published Gene Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intervertebral disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.754537
PPARA-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Renal Insufficiency	DisGeNET Gene-Disease Associations	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
Adult Fanconi Syndrome	DisGeNET Gene-Disease Associations	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03538
Osteoblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.779
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IT-01A-31R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.086981
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.931298
AHR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8502
Gracile nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38985
regulation of phosphate transport	GO Biological Process Annotations 2015	1.0	null
RAC3-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.985816
mortality/aging	MPO Gene-Phenotype Associations	1.0	null
ZNF584	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42517
Hypophosphatemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.26
Adrenocortical carcinoma_ACC_TCGA-OR-A5K0-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
TCF7L2	ChEA Transcription Factor Targets	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976207
GRIN2B	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_14531_KO_Ptf1a_SRP111204	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BRD-K22071228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37732
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.7401
HCC15	CCLE Cell Line Gene Expression Profiles	1.0	1.57674
Microvillus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.26
PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-Proximal_Tubule_Enriched_Genes_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
medial part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14231
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.764527
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
increased urine calcium level	MGI Mouse Phenotype Associations 2023	1.0	null
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.755
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27964
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.68385
BRD-K40490682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.17584
central gray of the pons, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.961531
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
PLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16858
Waist-to-hip ratio adjusted for BMI (age <50)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.652288
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1273f	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Mesonephric duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
skeleton phenotype	MPO Gene-Phenotype Associations	1.0	null
decreased birth body size	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K72997741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02518
FGF23 signaling in hypophosphatemic rickets and related disorders	WikiPathways Pathways 2024	1.0	null
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.63421
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
Sodium-dependent phosphate transport protein 2A	InterPro Predicted Protein Domain Annotations	1.0	null
U178	Achilles Cell Line Gene Essentiality Profiles	1.0	1.12655
Ectorhinal area/Layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32695
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A6V1-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27882
single-organism process	GO Biological Process Annotations 2015	1.0	null
Factor XII deficiency disease	ClinVar Gene-Phenotype Associations 2025	1.0	null
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070998
Calcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.265
CRCGN012_HEPG2_24H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04446
GSK3B_KD_GDS4305_179_human_HL-60 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.38115
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33716
DELE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74971
BRD-K20912596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13335
renal proximal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.89513
mecamylamine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28799
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2745
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.53028
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE234340_1_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Estimated glomerular filtration rate in diabetes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K17136501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23512
BRD-K35404627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48593
Primary hyperoxaluria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
Estimated glomerular filtration rate	GWAS Catalog SNP-Phenotype Associations 2025	1.0	5.92218
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.458
abnormal bone structure	HPO Gene-Disease Associations	1.0	null
therefore	GeneRIF Biological Term Annotations	1.0	null
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.09911
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.037
BRD-K13526564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36153
BRD-K35413741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0531
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMAD1-26771354-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
A673	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55557
muscle weakness	MGI Mouse Phenotype Associations 2023	1.0	null
Perturb_14960_KO_Tfap4_SRP212619	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.75146
ARHGAP35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17222
abnormal mineral level	MPO Gene-Phenotype Associations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-US-A774-01A-21R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7045-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K24950073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33695
BRD-K27229533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44983
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12176
CAMK2D	Pathway Commons Protein-Protein Interactions	1.0	null
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7412
Autosomal dominant hypophosphatemic rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.841
REH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0305
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.87
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.18
hypersensitivity reaction type ii disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047139
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dendritic spine neck	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.936
abnormal vitamin level	MPO Gene-Phenotype Associations	1.0	null
NB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59212
Kidney Chromophobe_KICH_TCGA-KL-8329-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K10302728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64568
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5696-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stratum intermedium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.568
GSE132759_4_v_0_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_10325_KO_Gsdmd_SRP318237	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
monoatomic ion transport	GO Biological Process Annotations 2023	1.0	null
SW403	DepMap CRISPR Gene Dependency	1.0	2.02812
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27232
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27976
BRD-K15236933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0591
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43969
glycoprotein metabolic process	GO Biological Process Annotations 2015	1.0	null
HEL9217	CCLE Cell Line Gene Expression Profiles	1.0	3.01199
FOXP1	ChEA Transcription Factor Targets	1.0	null
G292CLONEA141B1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.89323
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
SMUG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68887
PMC7335061-41467_2020_17150_MOESM4_ESM.xlsx-Table_S3-LIN28B_correlates_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
Kenny-Caffey syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
VMRC-RCW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
JMJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01342
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.874092
abnormal lipid level	MPO Gene-Phenotype Associations	1.0	null
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.02833
hsa-miR-3142	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5385
OVISE	CCLE Cell Line Gene CNV Profiles	1.0	1.34926
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.977316
GSE225684_0_v_2_tfap4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2827
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.858649
Tertiary granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.797
r8 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21771
CCRF-CEM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXA2-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IH-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.268969
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21526
Oncogenic Hypophosphataemic Osteomalacia	DisGeNET Gene-Disease Associations	1.0	null
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-regulation_of_membrane_potential_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1954	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GRIN1	Pathway Commons Protein-Protein Interactions	1.0	null
LHX1_NULL MUTATION - Ablation_GDS1748_748_mouse_Embryonic kidneys (from day E14.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
Transport of inorganic cations/anions and amino acids/oligopeptides	Reactome Pathways 2024	1.0	null
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5308
PHOX2B-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CG-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
U87MG	DepMap CRISPR Gene Dependency	1.0	2.41865
Dwarfism	DisGeNET Gene-Disease Associations	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.49202
Bone resorption disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.945
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12139
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.386208
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypoparathyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.160203
TE125T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66042
polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.394863
hydroxyamphetamine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00315
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976207
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03344
postnatal lethality	MGI Mouse Phenotype Associations 2023	1.0	null
Gitelman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.325
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
renal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.07662
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.399492
Chronic Kidney Disease	DisGeNET Gene-Disease Associations	1.0	null
Apical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.446
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.902
cSARS Bat SRBD_12Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.62881
Nephrocalcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.94
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2679
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.96089
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.902389
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.911169
proximal tubulopathy	HPO Gene-Disease Associations	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
delayed bone ossification	MGI Mouse Phenotype Associations 2023	1.0	null
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.056757
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
sodiumdependent	GeneRIF Biological Term Annotations	1.0	null
CRCGN012_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56446
Vitamin D-dependent rickets	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.308
Interstitial matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.523
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WZ-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
SW1463	DepMap CRISPR Gene Dependency	1.0	2.4876
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_215_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.07169
renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.74226
phosphate transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
BRD-K22193148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5689
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28804
Chronic kidney disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46789
Nephrotic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
BRD-A14484404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67643
Kidney_CT1_Proximal Tubule Epithelial Cell Segment 2	HuBMAP ASCT+B Annotations	1.0	null
Nephrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.254
chronic kidney failure	GWASdb SNP-Disease Associations	1.0	1.78856
Vitamin D-dependent rickets type 2B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.674
abnormal skeleton morphology	MPO Gene-Phenotype Associations	1.0	null
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Parathyroid gland benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
HS294T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83447
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28089
FOXA1-27270436-LNCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72596
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basolateral nucleus (basal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.848499
BICR22	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54983
GSE193177_1_v_3_st266_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Basal ganglia calcification	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
cases	GeneRIF Biological Term Annotations	1.0	null
BRD-K54837534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13605
GSE210377_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5258-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney diseases	GAD Gene-Disease Associations	1.0	null
BRD-K12683022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31237
MRPS34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54552
excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	1.01738
Kidney Diseases	dbGAP Gene-Trait Associations	1.0	1.1785
ankylosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.759008
ecl1	GeneRIF Biological Term Annotations	1.0	null
HCC-78	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K38538662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3789
fusiform gyrus, left, bank of cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.937141
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34798837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01075
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.62728
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.758673
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Von Willebrand Disease	DisGeNET Gene-Phenotype Associations	1.0	null
GSE158197_0_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
reduced fertility	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7091
SIGMAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32873
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059619
hsa-miR-326	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CTCF_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEL270	DepMap CRISPR Gene Dependency	1.0	3.21633
Clear cell renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
hsa-miR-4726-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
H3K9ac_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
DSH1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.25525
SLC25A13	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00409492
vacuole-isolation membrane contact site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.531
CBFB_01_43	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.30256
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.88094
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Elementary body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
Renal fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.451
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0305
r9 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41531
BRD-K00938872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73688
BRD-K86155080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51151
abnormality of skeletal morphology	HPO Gene-Disease Associations	1.0	null
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
Ossifying fibroma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.68809
hyperphosphaturia	HPO Gene-Disease Associations	1.0	null
Cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.641
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Type 2 diabetes mellitus_Pancreas_GSE2470	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.26937
Hereditary angioneurotic edema	ClinVar Gene-Phenotype Associations 2025	1.0	null
Metaphyseal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.712
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093848
BRD-K20420220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20741
HS 294T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.878456
BRD-K97067262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01275
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25147
nephrolithiasis/osteoporosis, hypophosphatemic, 1	OMIM Gene-Disease Associations	1.0	null
Capsular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.833
GSE234340_10_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K27121064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03096
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1331
CRCGN017_MCF10A.TP53.M_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55211
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7885-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_17339_KO_Plag1_SRP095348	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.58197
cellular response to inorganic substance	GO Biological Process Annotations 2015	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
Bone matrix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.401
Phosphorus, Dietary	CTD Gene-Chemical Interactions	1.0	null
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39092
SNU520	CCLE Cell Line Gene CNV Profiles	-1.0	-2.33272
Hypophosphatasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.794
Nephrolithiasis	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.10458
inorganic anion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Jansen's metaphyseal chondrodysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.915
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34503
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.38253
GPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80735
hypophosphatemia	HPO Gene-Disease Associations	1.0	null
GSE107581_0_v_1_cd27_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Parathyroid hormone secreting cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.909
Lung squamous cell carcinoma_LUSC_TCGA-94-8491-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Failure, Chronic	DisGeNET Gene-Disease Associations	1.0	null
BRD-K93127164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83347
BRD-K44722555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12053
SK-MEL-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAMK2B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE180321_0_v_1_imperatorin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3713	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
npt2a	GeneRIF Biological Term Annotations	1.0	null
MLPH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0048593
Plantlet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.985
abnormality of the urinary system	HPO Gene-Disease Associations	1.0	null
BRD-K98140933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0378
Perturb_10916_KO_Ghr_SRP269490	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.4807
Hypophosphatemic nephrolithiasis/osteoporosis	ClinVar Gene-Phenotype Associations 2025	1.0	null
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12137
regulation of transport	GO Biological Process Annotations 2015	1.0	null
abnormality of body height	HPO Gene-Disease Associations	1.0	null
PMC12263605-DataSheet1.pdf-257-IKZF3_IKZF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE185865_0_v_1_celf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K34277236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15733
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3526
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041556
BRD-K15478534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57988
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.753
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42933
786O	DepMap CRISPR Gene Dependency	1.0	2.04037
BRD-K50129495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43913
BRD-K60337516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29268
Bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.658
MAX	ENCODE Transcription Factor Targets	1.0	null
membrane	GeneRIF Biological Term Annotations	1.0	null
Osteogenic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.228
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55434
Primary somatosensory area, trunk, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0925
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K68667113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54333
CRCGN016_MCF10A.WT.HP_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68969
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 5 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1225
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
Kidney_CT1_Proximal Tubule Epithelial Cell Segment 1	HuBMAP ASCT+B Annotations	1.0	null
Lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41724
hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044323
Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92646316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21084
outer CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03955
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A6I9-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
control	GeneRIF Biological Term Annotations	1.0	null
Episodic ataxia type 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.134
C1QL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2152
molecular_function	GO Molecular Function Annotations 2015	1.0	null
BRD-K64804596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54353
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6579
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Human - Kidney - L3 - Proximal Tubule Epithelial Segment 1	HuBMAP Azimuth Cell Type Annotations	1.0	null
RALA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1826
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Somatosensory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3459
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
type	GeneRIF Biological Term Annotations	1.0	null
Chronic Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
OK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.472
CRCGN016_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5042
periventricular stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11401
membrane part	GO Cellular Component Annotations 2015	1.0	null
BRD-K19161227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03905
small molecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A6C0-01A-12R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17705111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69367
CRCGN012_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5522
BRD-K16403365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77465
Ankylosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
Pod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-h-Classification_of_camel_SON_basal_genes_-_transporters_SON	Rummagene Transcription Factor Associations 2026	1.0	null
Urinary system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	2.037
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
XRCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31217
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1033
cellular response to stimulus	GO Biological Process Annotations 2015	1.0	null
BRD-K19118372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.90819
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.23058
NCI-H524	GDSC Cell Line Gene Expression Profiles	1.0	1.82195
GSE181821_1_v_4_mov10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
low	GeneRIF Biological Term Annotations	1.0	null
AdrenalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.35678
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.982212
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4275	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
BRD-A97270959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.142
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.569
cervical adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.117634
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30106
postnatal lethality	MPO Gene-Phenotype Associations	1.0	null
BRD-K63107801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07907
BRD-K09106444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32625
Hereditary hypophosphatemic rickets with hypercalciuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.962
OV7	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46975
lethargy	MPO Gene-Phenotype Associations	1.0	null
Ureter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.18
inorganic anion transport	GO Biological Process Annotations 2023	1.0	null
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GFI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07313
response to magnesium ion	GO Biological Process Annotations 2015	1.0	null
step	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autoimmune disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.235
BRD-K32702774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61925
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0467
superficial stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44048
Apical part of cell	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Entorhinal area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36216
abnormal bone structure	MPO Gene-Phenotype Associations	1.0	null
DDT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03755
modulation	GeneRIF Biological Term Annotations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Basal plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.044
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nephrolithiasis	DisGeNET Gene-Disease Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80M-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.091311
ZNF542P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73681
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053022
DFCI024	CCLE Cell Line Gene Expression Profiles	1.0	1.48324
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
divalent inorganic anion homeostasis	GO Biological Process Annotations 2015	1.0	null
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070493
Odontoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.138
NFYA_02_76	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	6.19967
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.603
IRF8-27001747-CHIP-SEQ-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K33702515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4804
hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050338
abnormal trabecular bone morphology	MGI Mouse Phenotype Associations 2023	1.0	null
increased circulating alkaline phosphatase level	MGI Mouse Phenotype Associations 2023	1.0	null
NADK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21889
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.78498
SW1990	DepMap CRISPR Gene Dependency	1.0	2.4709
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864403
HS-445	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7XN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus of the solitary tract, commissural part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50277
FKBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46059
periventricular stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46687