association dataset threshold value standardized value NR2F2 ENCODE Transcription Factor Targets 1.0 null GTEX-XBED-1426-SM-4AT4G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ZNF347 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93872 SNU1079 DepMap CRISPR Gene Dependency 1.0 2.06127 AK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.1084 GTEX-WI4N-2726-SM-3LK7Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 VAMP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82427 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51H-06A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-PC-A5DN-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MOSMO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86251 ZNF436 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14298 IKBKG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70684 Myosin X complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.668 SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05325 BCL6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98631 POLR2A_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SIU7-0426-SM-2XCDX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 EXOSC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86096 CAL851 CCLE Cell Line Gene CNV Profiles -1.0 -1.59225 GTEX-XBED-2626-SM-4E3J5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Prostate adenocarcinoma_PRAD_TCGA-KK-A7B3-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WXYG-2226-SM-4E3IM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Promastigote TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.911 mcf7 HPA Cell Line Gene Expression Profiles 1.0 0.990807 IZUMO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39497 ZNF326 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33991 H3K9me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TKT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54736 OCI-AML3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40148 CUX1-19635798-MULTIPLE HUMAN CANCER CELL TYPES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H3K9me3_U2OS_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null UBE3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28077 IQGAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46925 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8003-01A-21R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H810 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-U3ZM-0526-SM-4DXTB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-QESD-1426-SM-2S1R9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GATA1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.73999 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A553-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bone marrow cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060664 GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 2.32096 pc3 HPA Cell Line Gene Expression Profiles 1.0 1.1034 RREB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 134.455 MIER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.35569 muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.066383 TT2609-C02 COSMIC Cell Line Gene Mutation Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GY-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC3526425-1471-2164-13-572-S3.xlsx-STAT6-STAT6_STAT6 Rummagene Transcription Factor Associations 2026 1.0 null NKX2-8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6699 ZNF281 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 145.045 GTEX-WFG7-0005-SM-3GIKM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.71442 GTEX-S4P3-0926-SM-4AD54 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Brain Lower Grade Glioma_LGG_TCGA-S9-A6U6-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hek293 HPA Cell Line Gene Expression Profiles -1.0 -0.826749 MYO18A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34277 RERF-LC-SQ1 COSMIC Cell Line Gene Mutation Profiles 1.0 null ENKD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10065 TE-10 COSMIC Cell Line Gene Mutation Profiles 1.0 null ETV5::HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1255 NKX2-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27229 Brain Lower Grade Glioma_LGG_TCGA-HT-8104-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XLM4-0426-SM-4AT54 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ZNF621 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24017 GID8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7728 GTEX-QLQ7-1526-SM-2S1QA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ASNS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13871 GTEX-QCQG-2026-SM-2S1PH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Urogenital system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.527 SRSF9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.06007 GTEX-POYW-0826-SM-2XCEM GTEx Tissue Sample Gene Expression Profiles 1.0 1.16127 CRIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51607 membrane LOCATE Predicted Protein Localization Annotations 1.0 null Salivary_Gland-naive b cell Tabula Sapiens Gene-Cell Associations 1.0 1.59235 Zic3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.8364 TMEM88B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75684 LARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28371 GTEX-WFG8-2326-SM-3GILF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NR4A2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5305 Brain Lower Grade Glioma_LGG_TCGA-E1-A7Z3-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FUT10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74353 GTEX-SE5C-0008-SM-4B64J GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 MFHAS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46759 Scutellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.779 PAK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00565 GTEX-PWOO-0326-SM-48TDB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-R55G-0926-SM-48FDN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-SSA3-0126-SM-32QPU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 mononuclear cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.139053 Intracranial thrombosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.235 Brain Lower Grade Glioma_LGG_TCGA-FG-8191-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AX-01A-12R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N5-A4RD-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.046143 GTEX-U3ZN-1826-SM-4DXUY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-T6MO-0126-SM-4DM6X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 SLC25A38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80449 DCP1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93483 GTEX-XMK1-2526-SM-4B666 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Male reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.656 CHCHD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40937 GTEX-UJHI-1026-SM-4IHJP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-XOTO-2826-SM-4B65I GTEx Tissue Sample Gene Expression Profiles 1.0 1.43957 GTEX-XMK1-2226-SM-4B673 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QJ-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HSDL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34264 Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SJXC-0008-SM-4DM7G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-S32W-0826-SM-4AD5Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.870185 ABHD17A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4919 Pancreatic adenocarcinoma_PAAD_TCGA-Q3-AA2A-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S4Q7-1426-SM-3K2B9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 BAHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78393 Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RO-01A-12R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null Adrenocortical carcinoma_ACC_TCGA-P6-A5OG-01A-22R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF549 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 64.4237 KPNYS DepMap CRISPR Gene Dependency 1.0 2.30911 RFXANK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37208 RPP25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13955 ELK4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3137 Lung squamous cell carcinoma_LUSC_TCGA-60-2708-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NECTIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50243 ASPSCR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92256 skeletal system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051563 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 hematopoietic system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.062585 PAX5 ENCODE Transcription Factor Targets 1.0 null GTEX-QDVN-2326-SM-2S1PF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.837431 medial mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.26397 ATXN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87128 GTEX-XQ8I-1726-SM-4BOQB GTEx Tissue Sample Gene Expression Profiles 1.0 1.27453 PMC8891017-41586_2022_4394_MOESM4_ESM.xlsx-ST6_-_MAF_enrichment-Unnamed_4_MAF Rummagene Transcription Factor Associations 2026 1.0 null SHOC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15622 occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.947934 GTEX-R55D-0006-SM-3GIJS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Pancreatic gastrinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.097 C15orf62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88678 ENTPD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85437 GTEX-WFON-0426-SM-3GIL4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 TARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06046 hsa-miR-339-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 SARAF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.72197 frontal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.0631 TOMM70 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46643 muscle GTEx Tissue Gene Expression Profiles -1.0 -1.48927 GTEX-UTHO-2726-SM-4JBH9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.45035 GTEX-S7SF-0226-SM-3K2BI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 MGRN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5081 GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 2.21616 GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.73439 SLC39A7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03733 GTEX-R45C-1226-SM-48FEE GTEx Tissue Sample Gene Expression Profiles 1.0 1.20442 SP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77759 KIF1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91674 PCCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.40136 caudal prosubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00362 Rectum adenocarcinoma_READ_TCGA-DY-A1DE-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLHL31 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67319 GTEX-TML8-1526-SM-4DXUX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 CTCF ENCODE Transcription Factor Targets 1.0 null GTEX-PWN1-0226-SM-2S1OZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Lung squamous cell carcinoma_LUSC_TCGA-77-7337-01A-21R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WFON-1726-SM-4LVMQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 CUX1 ChEA Transcription Factor Targets 1.0 null 496100304_HIP_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.11493 prostate carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.248905 GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 2.06152 GTEX-WEY5-0006-SM-3GIKG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-OXRN-2426-SM-2I5EQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ERG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23452 KU812 COSMIC Cell Line Gene Mutation Profiles 1.0 null BCL6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6276 ARID4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.6685 GTEX-QEG5-0926-SM-2TC64 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14195 IM-95M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40148 CSPG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05001 GTEX-U4B1-0126-SM-4DXSN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-P4QS-0726-SM-3NMCZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-QV31-0626-SM-447C5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 vascular smooth muscle cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.267102 ITLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.363 GTEX-X4EP-3226-SM-3P5YR GTEx Tissue Sample Gene Expression Profiles 1.0 1.05347 CERS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17536 DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.60454 ZSCAN31 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.8931 urinary bladder HPA Tissue Gene Expression Profiles -1.0 -1.02139 KLRG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04204 viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050644 GTEX-QLQ7-1726-SM-2S1QQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-R3RS-0008-SM-48FF1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 phagocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.144625 GTEX-VJWN-0726-SM-3GIJ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-S33H-2426-SM-2XCB2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Large latent transforming growth factor-beta complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.509 GTEX-SJXC-0326-SM-2XCFI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 SP1 ENCODE Transcription Factor Targets 1.0 null KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.97003 GTEX-WHPG-1026-SM-3NMBA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-P78B-1626-SM-2S1O1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 MG63 DepMap CRISPR Gene Dependency 1.0 5.06759 Adenomatoid tumor DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.038 EML3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57782 Lung squamous cell carcinoma_LUSC_TCGA-85-8479-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAST1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4084 GTEX-T8EM-1526-SM-3DB7I GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 RI1 DepMap CRISPR Gene Dependency 1.0 2.39494 GTEX-RM2N-1126-SM-48FCY GTEx Tissue Sample Gene Expression Profiles 1.0 1.18835 GTEX-V1D1-2026-SM-3GAF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PGAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13476 GTEX-XBEC-1526-SM-4AT68 GTEx Tissue Sample Gene Expression Profiles 1.0 0.990779 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.10798 GTEX-R55G-0326-SM-48FDM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Apocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.217 GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 1.49975 Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RWS6-2326-SM-2XCB4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ETV7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3144 UNC5D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02985 KLF6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.27464 hepg2 HPA Cell Line Gene Expression Profiles -1.0 -0.826749 GTEX-OIZI-0005-SM-2XCED GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCOR3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84112 Lung adenocarcinoma_LUAD_TCGA-86-A4P8-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UTHO-1026-SM-3GAF7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 STAT3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2774 DOLK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31791 ATOSB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20235 GTEX-XYKS-0926-SM-4BRVG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 RORC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21168 peripheral blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.086948 dexamethasone_homo sapiens_gpl6244_gse20963 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null DOTC2-4510 COSMIC Cell Line Gene Mutation Profiles 1.0 null PL4 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2AphosphoS2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HUP-T4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.62029 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WYBS-0426-SM-3NM9M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 CXCL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76537 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.57922 GTEX-Q2AG-0426-SM-2S1PU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 LRRC14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23599 CFP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69619 HINFP JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8497 496100596_FWM_dementia_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.10277 FH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20531 Prostate cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.656 III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.993686 KRTCAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3673 NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.933666 GRK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62026 GTEX-NPJ8-0007-SM-2D7VX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 abdomen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.076859 UVSSA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36155 oculomotor nuclear complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.22867 CDC42BPG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81017 TRIM45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33965 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null PAX5_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 2.10272 GTEX-WFG8-0326-SM-4LVN4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2269 GTEX-R55E-2526-SM-2TC6H GTEx Tissue Sample Gene Expression Profiles 1.0 0.96014 central gray of the pons, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.836982 639-V COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-PVOW-1026-SM-2XCF9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.22827 RXRG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 95.6713 KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01453 VOPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23298 NPRL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3863 MLEC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60826 GTEX-XAJ8-1226-SM-47JYS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-VUSG-0726-SM-3GIK1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ZBED4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 93.8621 ARID2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73508 LUC7L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92546 GTEX-QMR6-0011-R6A-SM-32PKP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-R55C-0726-SM-48FCN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A9FF-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T2IS-3026-SM-32QPM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 FKRP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.46541 Liver hepatocellular carcinoma_LIHC_TCGA-DD-AA3A-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SJXC-0526-SM-2XCFG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-S341-1826-SM-3K2AB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-S4P3-0006-SM-3K2AW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Prostate adenocarcinoma_PRAD_TCGA-HC-7752-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PVOW-0011-R1A-SM-32PL6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PLXND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50865 AKIRIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23497 TSEN15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22483 POR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65324 GTEX-S4UY-0126-SM-3K2BB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ELF1-20517297-JURKAT-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null SHISA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07408 OCI-LY-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.910293 RHEB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06381 GTEX-SNMC-0626-SM-4DM6H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 NB13 COSMIC Cell Line Gene Mutation Profiles 1.0 null RANBP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35073 POLR2A ENCODE Transcription Factor Targets 1.0 null ZNF213 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 77.7424 Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41O-01A-12R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100543_FWM_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.29996 GTEX-NPJ8-2426-SM-3MJHL GTEx Tissue Sample Gene Expression Profiles 1.0 1.04121 GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 2.04441 GTEX-SNMC-1626-SM-4DM52 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00187 MCM8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40915 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null PPP1R3E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84351 GTEX-Q734-2226-SM-3GAD9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T8EM-0426-SM-4DM7E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 lateral hypothalamic area, tuberal region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.963879 aorta TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.144087 cytoplasmic membrane-bounded vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.068447 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MH-01A-12R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STEAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10875 NBPF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9475 HUS1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90663 PMC9686236-41598_2022_24611_MOESM1_ESM.xlsx-Suppl_Table_10-Supplemental_Table_10_Significant_genes_in_MR_analyses_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-PWCY-0426-SM-48TCW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-QCQG-1526-SM-48U25 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-X4XX-0011-R11A-SM-46MWQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.922499 496100474_FWM_possible Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.10608 MAGED4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29309 GTEX-QCQG-0126-SM-48U27 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 TMEM167B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50386 GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 1.73496 GSTP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87093 DANG DepMap CRISPR Gene Dependency 1.0 2.3273 cholera DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.157765 CRB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12061 HAPLN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54551 Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A55Z-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IGFBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60842 HES2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7924 GTEX-UPIC-0726-SM-3GADW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WFON-0926-SM-4LVMK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-RVPV-1226-SM-2TF73 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 CTCF_kidney_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-POYW-0006-SM-2XCF4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 MLXIPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70456 GTEX-OIZI-0526-SM-2XCEG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Acute Myeloid Leukemia_LAML_TCGA-AB-2983-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF135 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89956 ZNF354C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8125 outer CP in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00778 SNU-449 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.892319 GTEX-OXRP-2326-SM-2S1NL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Obesity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.95 megakaryocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.149237 monocyte-derived dendritic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.305001 Lipid metabolism disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.075 GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 2.50923 mononuclear phagocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.160897 dorsal lateral geniculate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22727 GTEX-XPVG-1826-SM-4B64X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PAX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24687 GTEX-WCDI-0426-SM-4GIAL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-XBED-1326-SM-4AT4F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-P4PP-1426-SM-3NM9L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 RAD52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6474 GTEX-OHPM-0326-SM-33HCA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 MTAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39876 layer I of piriform cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.953885 central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.96817 Hmga1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.4843 MRPL16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6804 KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28316 multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02211 PMC10274973-media-3.xlsx-ST18-Unnamed_9_ST18 Rummagene Transcription Factor Associations 2026 1.0 null ZFAND4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78681 PPP1CB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5798 GSE195559_0_v_4_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LL-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U412-0826-SM-3DB9K GTEx Tissue Sample Gene Expression Profiles 1.0 1.19883 NR2C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2184 GTEX-RVPV-0011-R3A-SM-2TF63 GTEx Tissue Sample Gene Expression Profiles 1.0 0.925632 lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06273 Gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.037 Insulin Resistance HuGE Navigator Gene-Phenotype Associations 1.0 null GTEX-N7MS-2625-SM-3LK77 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81W-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-W3-A824-06A-21R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WXYG-2326-SM-4E3I6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 DDX27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76455 KIAA1549 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35893 GTEX-UTHO-0011-R4A-SM-3GIJP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 G292CLONEA141B1 CCLE Cell Line Gene CNV Profiles 1.0 2.59972 POU2F2 JASPAR Predicted Transcription Factor Targets 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8336-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MPST CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16066 INKA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84452 ZNF184 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.6279 PGBD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.36879 P31-FUJ COSMIC Cell Line Gene Mutation Profiles 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null GTEX-N7MS-0011-R8a-SM-2YUMK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EC-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S95S-1626-SM-2XCDJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 SKMEL24 DepMap CRISPR Gene Dependency 1.0 2.40964 FZD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77944 GIPC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77349 PIGH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60558 PRRT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13279 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.95 GTEX-U412-2026-SM-4DXSI GTEx Tissue Sample Gene Expression Profiles 1.0 0.829117 GTEX-W5WG-0006-SM-3GIJT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 extrinsic allergic alveolitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.480566 GTEX-OXRO-1226-SM-48TDL GTEx Tissue Sample Gene Expression Profiles 1.0 0.95064 PDCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82919 MDAPCA2B CCLE Cell Line Gene CNV Profiles 1.0 1.47597 posterior group of nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.936875 OPM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.850492 LTO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98812 GTEX-WFG7-0326-SM-3GILI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04107 ascospore-type prospore COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.751 RHPN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37257 hematopoietic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060499 familial hyperlipidemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.30631 RAPGEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68867 GTEX-UJMC-0226-SM-4IHLH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-Q2AH-1626-SM-3GAF8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-T2YK-0008-SM-4DM6M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.922142 BRCA1 JASPAR Predicted Transcription Factor Targets 1.0 null medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.49918 Lung adenocarcinoma_LUAD_TCGA-55-6969-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RH-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 2.29035 Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PPIG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05138 angiosarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.471468 GSE216273,GSE216292_14_v_2_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.9833 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF804A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90888 CDY2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89653 IKZF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09307 GTEX-S7SF-2026-SM-3K2AS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-OHPK-1826-SM-2YUMR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 NACC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56753 Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RNASEH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95822 FOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 89.563 Lung adenocarcinoma_LUAD_TCGA-50-5051-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PL4 DepMap CRISPR Gene Dependency 1.0 3.71183 GTEX-S4P3-0626-SM-4AD59 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6972-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100367_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.03404 GTEX-RVPU-0011-R9A-SM-3NM8E GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ETV2::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.5786 GTEX-RWS6-2126-SM-2XCAV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 POLR2AphosphoS2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HGS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71978 SURF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42513 NCIH2023 DepMap CRISPR Gene Dependency 1.0 2.89104 ESR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.4613 FOXE1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.3928 GTEX-OHPM-0526-SM-2YUMJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PCBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.19986 RNF126 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11025 GTEX-QDVJ-1826-SM-2S1P3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 H3K36me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05074 Prostate adenocarcinoma_PRAD_TCGA-KK-A7AU-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NDUFB9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.63739 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.925458 cingulate gyrus, retrosplenial part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.873193 central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.92897 Dyslipidemias HuGE Navigator Gene-Phenotype Associations 1.0 null GTEX-R53T-2026-SM-3GIJF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 NCI-H1648 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZNF490 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.35451 RBBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.21282 GTEX-QMR6-0011-R4A-SM-32PKU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NPTX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85465 GTEX-V955-2026-SM-3GAFA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 temporal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.85483 SLC38A5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31017 hl60 HPA Cell Line Gene Expression Profiles -1.0 -0.826749 Lung adenocarcinoma_LUAD_TCGA-95-A4VP-01A-21R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 97.2179 GTEX-T2IS-0011-R3A-SM-32QPB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041784 Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T3-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XXEK-0126-SM-4BRVU GTEx Tissue Sample Gene Expression Profiles 1.0 1.38339 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46975 GTEX-WFG8-0426-SM-3GILD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.02407 GTEX-PWN1-2526-SM-48TDS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 rnf2_21051595_92dot1_lof_human_gpl10558_gse24896 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.059434 GTEX-QEL4-0526-SM-3GIJ4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 KCL22 CCLE Cell Line Gene CNV Profiles 1.0 1.94519 POLR2A_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58459 GTEX-XQ3S-0626-SM-4BOOB GTEx Tissue Sample Gene Expression Profiles 1.0 1.32749 ZNF75A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87774 SKNMC CCLE Cell Line Gene CNV Profiles 1.0 2.073 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.423265 leukocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063299 SERPING1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20142 GTEX-XXEK-0326-SM-4BRVV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Cell type cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.656 CHD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4215 motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06686 GTEX-R55G-1126-SM-48FDG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Edinger-Westphal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.1656 substantia nigra, pars reticulata, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.11535 CRIP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.19662 Hyalocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.761 BXPC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.835073 CBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24475 GTEX-U3ZM-0426-SM-3DB73 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Acute Myeloid Leukemia_LAML_TCGA-AB-3011-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55G-1226-SM-48FDC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-WFG7-2326-SM-3GIKV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 SARS-CoV_60Hour_23935999_GSE47961 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.51117 CABIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21128 AMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85796 ZNF609 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60899 496100314_HIP_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.37838 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.46113 GTEX-SE5C-0926-SM-4BRUF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 CYCS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50858 VMRCLCD DepMap CRISPR Gene Dependency 1.0 3.56449 GTEX-UJHI-0226-SM-4IHJL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 VIIB, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.906773 GTEX-XAJ8-0006-SM-46MVM GTEx Tissue Sample Gene Expression Profiles 1.0 1.09215 PIDD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25554 GTEX-OIZH-0926-SM-48TBR GTEx Tissue Sample Gene Expression Profiles 1.0 1.2623 prostate cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.074487 outer SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16391 GTEX-SIU8-0826-SM-2XCDQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.42386 JHH-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82532 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MF-01A-12R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.66442 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7383-01A-11R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TSE9-3126-SM-4DXSY GTEx Tissue Sample Gene Expression Profiles 1.0 0.990104 OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.2615 cardiovascular cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.543155 PDPR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.77849 Prostate adenocarcinoma_PRAD_TCGA-EJ-7789-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dendritic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.142135 Intracellular immature spore COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.718 GTEX-OOBJ-2626-SM-2I3F6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.964733 GSE201657_0_v_1_ash2l_human RummaGEO Gene Perturbation Signatures 1.0 null rostral migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13595 DCAF17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51062 GTEX-TMZS-0006-SM-3DB8G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.969332 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44R-06A-41R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Organ system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.656 SLC1A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02413 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HX-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Disease of cellular proliferation DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.656 GTEX-POYW-1226-SM-2XCEP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-QDT8-0011-R1A-SM-32PKS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A-Netherlands-602-2009(H1N1)_3Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.23183 MEOX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15308 GTEX-T6MO-1526-SM-4DM57 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 LPXN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04365 SELENOV CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8657 ZNF532 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68862 POLR2H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27915 dentate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.951651 GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.49025 HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06815 Sarcoma_SARC_TCGA-DX-A6BH-01A-12R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.42162 GTEX-WHSE-0011-R8A-SM-3P5Z1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.93957 H3K9me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Syndrome HuGE Navigator Gene-Phenotype Associations 1.0 null GTEX-WHWD-2426-SM-3LK6S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.973222 CHSA0011 COSMIC Cell Line Gene Mutation Profiles 1.0 null culture condition TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.347038 IM-95 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.58438 GTEX-WFG7-1326-SM-4LMK1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Intracranial sinus thrombosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.676 ZZEF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0377 GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 1.70722 TOP2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.35858 GTEX-VJYA-0326-SM-3GAEX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 KDM5B_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 18691415-Table5d GeneSigDB Published Gene Signatures 1.0 null GTEX-POMQ-0126-SM-48TD6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.916349 Processed meat consumption GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.939794 lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.30661 GTEX-QCQG-1726-SM-3GIJ9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-QDVJ-0005-SM-2TC5X GTEx Tissue Sample Gene Expression Profiles 1.0 1.19245 GTEX-X585-0005-SM-46MV3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19101 RABEP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98313 AAAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9856 Liver hepatocellular carcinoma_LIHC_TCGA-EP-A3JL-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TML8-2026-SM-32QOP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-OOBK-0005-SM-2YUMG GTEx Tissue Sample Gene Expression Profiles 1.0 1.12483 GTEX-TSE9-0726-SM-3DB8C GTEx Tissue Sample Gene Expression Profiles 1.0 1.06896 GTEX-UPK5-1626-SM-4JBHI GTEx Tissue Sample Gene Expression Profiles 1.0 1.60739 SNG-M COSMIC Cell Line Gene Mutation Profiles 1.0 null ZNF582 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.058 Nutrition disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.95 rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04695 dyslipidemias; hypertriglyceridemia GAD Gene-Disease Associations 1.0 null SGPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22587 ERV3-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43924 outer plexiform zone in extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.952858 GTEX-U3ZN-0826-SM-4DXSZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.896599 GTEX-PLZ6-1726-SM-2S1O6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-S32W-2526-SM-2XCB8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.881 Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-11A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2BC18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38286 ARID4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81512 COMMD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03588 cell culture TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.432225 IZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.987453 GTEX-XBED-2326-SM-47JYR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Acute Myeloid Leukemia_LAML_TCGA-AB-2848-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QVJO-1626-SM-2S1QW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 SEC24A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87207 APEX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68043 MOB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44572 ICC4 DepMap CRISPR Gene Dependency 1.0 2.19307 Amastigote TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.901 Lung adenocarcinoma_LUAD_TCGA-55-7574-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040863 GTEX-V955-1226-SM-4JBI9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 LDAH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12089 disease by infectious agent DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040063 SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2264 GOSR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0652 TRIP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76107 CTNS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72746 DU-145 COSMIC Cell Line Gene Mutation Profiles 1.0 null TFAP4::ETV1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.3678 SFXN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.99654 MCCC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18375 GTEX-TMZS-0326-SM-3DB9P GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 MSRB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16029 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84779 ROBO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13972 WWC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24497 GTEX-WFON-0226-SM-3GIKR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 periventricular nucleus, preoptic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.63032 SOX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3553 GTEX-R55F-1226-SM-2TF59 GTEx Tissue Sample Gene Expression Profiles 1.0 0.849415 MED29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.9212 ERCC6L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.68397 GTEX-XLM4-0005-SM-4AT4P GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 DUXB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93697 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6488-01A-12R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050474 Lung squamous cell carcinoma_LUSC_TCGA-56-A4ZJ-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T5JC-0011-R11A-SM-32PMB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Prospore membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.753 GTEX-P4QT-1826-SM-2S1NJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 CTAGE4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61345 TTC549 DepMap CRISPR Gene Dependency 1.0 4.0962 facial motor nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.26344 Genetic Predisposition to Disease HuGE Navigator Gene-Phenotype Associations 1.0 null ACTR5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23993 JHH4 CCLE Cell Line Gene CNV Profiles -1.0 -2.29292 HCC70 COSMIC Cell Line Gene CNV Profiles -1.0 -3.12964 GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.2566 Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A50I-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.06503 496100603_PCx_probable Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.74548 FANCF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61137 DPM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36374 superior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04801 GTEX-RM2N-1926-SM-48FCU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-Q734-1926-SM-2I5EV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 smooth muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.117889 EamA domain InterPro Predicted Protein Domain Annotations 1.0 null ERF::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3454 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040902 OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.31658 Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TTLL13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42308 Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-11A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2877-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T5JC-1526-SM-4DM68 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Lower respiratory tract disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.656 epidermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.447961 Rhoptry neck COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.589 MZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.41167 medial orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.912487 GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 1.59322 EmrE multidrug transporter complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.605 posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.905371 FCHO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15277 RNF213 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95653 LAMA84 CCLE Cell Line Gene CNV Profiles 1.0 1.39258 GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 2.3593 GTEX-TSE9-2526-SM-4DXUS GTEx Tissue Sample Gene Expression Profiles 1.0 0.983208 GTEX-XV7Q-0926-SM-4BRVQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.84013 GTEX-UTHO-0011-R5A-SM-3GIJD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 SMARCB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65296 SP8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 77.7248 GTEX-WFG8-1826-SM-4LVM4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11241 Lung squamous cell carcinoma_LUSC_TCGA-98-A539-01A-31R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.98534 capillary TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.922055 TCF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46843 CTSK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03232 SIG-M5 COSMIC Cell Line Gene Mutation Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-DY-A1DF-01A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WHSE-0011-R1A-SM-3P5ZK GTEx Tissue Sample Gene Expression Profiles 1.0 1.15199 496100316_TCx_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.09843 PPM1F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76344 GTEX-RN64-1626-SM-48FD7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.982149 COLO783 CCLE Cell Line Gene CNV Profiles 1.0 1.56843 NF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86499 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BK-01B-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sperm plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.633 FARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87493 GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 2.02008 CSNK1G2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51519 OCUM-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.949557 Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SH-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SYCP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50365 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GTEX-NFK9-1526-SM-3LK7B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PMC9164515-5-12-22-eQTL_Supplemental_tables_ScientificReport.xlsx-Suppl_Table_8-Supplemental_Table_8_Significant_genes_in_MR_analyses_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null PMC10882188-ADB-29-e13365-s002.xlsx-ST18-Unnamed_8_ST18 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.7083 basal ventral medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08154 GTEX-SNMC-1326-SM-2XCFK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-VUSG-1726-SM-4KKZL GTEx Tissue Sample Gene Expression Profiles 1.0 1.5336 GTEX-T6MO-0426-SM-32QOI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 B3GNT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56531 GTEX-P4PP-1726-SM-2S1NS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GSE171572_3_v_2_tp53_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-T6MN-0126-SM-32PLP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 DNAAF9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93347 SLC25A13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03983 Reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.527 MRPL23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18341 ACADVL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13444 Lung adenocarcinoma_LUAD_TCGA-78-7535-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null t47d HPA Cell Line Gene Expression Profiles -1.0 -0.826749 INF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.09865 ECC10 CCLE Cell Line Gene CNV Profiles 1.0 1.66068 MOLM13 CCLE Cell Line Gene CNV Profiles 1.0 1.65637 PIM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75782 GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 1.91574 TMEM222 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56161 8505C DepMap CRISPR Gene Dependency 1.0 2.51529 NLRP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13659 NCI-H460 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-SJXC-0726-SM-2XCFJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 blood plasma TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.33413 ATP1A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25545 SOCS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09541 HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28316 scale TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.212586 Chronic obstructive pulmonary disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.656 GTEX-UTHO-0011-R6A-SM-3GIJW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 RBM15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19595 PRAME CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09836 GTEX-X5EB-2426-SM-4E3HX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 POLR2AphosphoS5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null WSU-DLCL2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40148 COX6A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85818 BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.906981 SMC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61191 SLC39A10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42142 Schizont TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.008 TFPI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56228 LATS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4429 UNKL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38826 GTEX-QESD-1626-SM-2S1RB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EO-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TESMIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89093 GTEX-WFJO-0626-SM-4LVMC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.6917 TRIM32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23718 fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.60508 ZNF878 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11207 EWSR1-FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 295.6 ISCA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36115 ELF1 ChEA Transcription Factor Targets 1.0 null TP53 JASPAR Predicted Transcription Factor Targets 1.0 null CKLF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32368 NCI-H2009 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.988143 MMP25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41682 Acquired metabolic disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.95 MT-CYB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9444 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.99132 LYL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29617 GTEX-TSE9-0005-SM-4DXUF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ZNF184 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21935 GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 1.37125 Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OCI-AML5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.58474 STK40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9586 CSNK2A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12549 Prostate adenocarcinoma_PRAD_TCGA-M7-A724-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NB10 DepMap CRISPR Gene Dependency 1.0 6.94683 NB17 COSMIC Cell Line Gene Mutation Profiles 1.0 null XPA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30082 spleen HPA Tissue Gene Expression Profiles 1.0 1.00761 APOBEC3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.2701 RFX8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.29898 GTEX-QXCU-0626-SM-2TC69 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.54788 ANKRD13C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55664 AHSA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73438 MTHFD1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69258 SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.48072 GSE77108_0_v_1_saha_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-UTHO-1826-SM-3GAFE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OOBK-0226-SM-2YUMF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-NFK9-0008-SM-4E3JE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-REY6-0326-SM-2TF5A GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 TBX2-33478486-IMR90-HUMAN-LUNG ChEA Transcription Factor Targets 2022 1.0 null E2F6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.4488 GTEX-X62O-0826-SM-46MW8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.31032 PRDM16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18467 membrane part GO Cellular Component Annotations 2015 1.0 null GTEX-V1D1-2626-SM-4JBJH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 2.0758 vascular cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.570329 STRADB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24711 496100643_TCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.11475 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6011-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MKN7 CCLE Cell Line Gene CNV Profiles -1.0 -1.34959 GTEX-S7SE-0726-SM-2XCD7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.984675 PFKL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27299 CHPT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70207 Oxyntic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.817 SCC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A204 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XAJ8-0626-SM-47JY4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.14324 ZFP42 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.6895 GTEX-S4Q7-0006-SM-3K2AT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-WL46-2826-SM-3LK81 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-XYKS-1326-SM-4BRUN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.68492 Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZN-0006-SM-3DB7Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-T5JW-0926-SM-4DM5K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PHF20L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40485 GTEX-WL46-0526-SM-3LK7W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ZNF263 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 118.739 OXNAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09164 SEMA3G CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54402 GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 2.91817 rostral subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09679 Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QLQW-0126-SM-447BK GTEx Tissue Sample Gene Expression Profiles 1.0 0.995836 IRF2 JASPAR Predicted Transcription Factor Targets 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNRNP40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69059 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GTEX-Q2AI-1526-SM-3GIJ3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ZNF681 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25048 GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.95542 H3K9me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CEBPD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07274 HTR3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.57928 Lung adenocarcinoma_LUAD_TCGA-55-A48X-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null salivary gland HPA Tissue Gene Expression Profiles -1.0 -1.02139 PATZ1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 183.987 Familial combined hyperlipidemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.39 GTEX-WFG8-0926-SM-3GIKJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 MRE11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95178 TEFM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34775 GTEX-QMR6-0011-R11A-SM-32PKK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 SPATA24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52464 NO11 DepMap CRISPR Gene Dependency 1.0 2.39052 GTEX-PLZ5-0006-SM-2S1NZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.33857 Lung adenocarcinoma_LUAD_TCGA-53-A4EZ-01A-12R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZM-1526-SM-3DB9D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PRDM13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.38787 ANKRD30A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35754 GTEX-OHPK-2426-SM-3MJGH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 CEP95 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78202 SLFN14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57168 TOPBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45249 high-density lipoprotein particle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.927 ZBTB24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53074 H3K9me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SLC16A13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15572 GTEX-Q734-0626-SM-2I3EF GTEx Tissue Sample Gene Expression Profiles 1.0 0.900151 HG3 DepMap CRISPR Gene Dependency 1.0 7.20972 AJUBA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21144 IZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11869 PMC11653668-ADVS-11-2400133-s002.pdf-8-TEF_TEF Rummagene Transcription Factor Associations 2026 1.0 null CYTH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99287 GTEX-QMR6-0011-R7A-SM-32PKL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 COV318 DepMap CRISPR Gene Dependency 1.0 2.76481 GUCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4847 Kidney Chromophobe_KICH_TCGA-KO-8409-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-33-4583-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LASP1NB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80581 aortic smooth muscle cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.644074 Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H345 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25019 HS 940.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32771 sarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.111346 DPY30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28789 Lung adenocarcinoma_LUAD_TCGA-05-4422-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR2C2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 94.5037 NSUN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49516 MZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14734 GTEX-P4QS-2026-SM-3NMCG GTEx Tissue Sample Gene Expression Profiles 1.0 1.1265 GTEX-R53T-1826-SM-3GIJX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 496100411_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.56514 Lung adenocarcinoma_LUAD_TCGA-86-7701-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XGQ4-0826-SM-4AT4T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GOLM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63961 TRPS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51952 GTEX-W5X1-2326-SM-3GIL6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 dorsomedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.824359 FSBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95183 GTEX-PW2O-1726-SM-2S1OO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 MPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72316 other source TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.431077 CCDC93 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.72687 GTEX-WHSE-3126-SM-3P5ZI GTEx Tissue Sample Gene Expression Profiles 1.0 0.937555 GTEX-T5JC-0426-SM-32PLO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.757 TAF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48784 Cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.656 ZNF35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95296 THP1 CCLE Cell Line Gene CNV Profiles 1.0 1.37639 organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.0418 GTEX-P4PP-1626-SM-2HMJF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Lung adenocarcinoma_LUAD_TCGA-50-5044-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XMD1-0011-R11A-SM-4AT5J GTEx Tissue Sample Gene Expression Profiles 1.0 1.16358 Disease of metabolism DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.95 DAN-G COSMIC Cell Line Gene CNV Profiles 1.0 2.14311 GTEX-QCQG-0006-SM-2S1OW GTEx Tissue Sample Gene Expression Profiles 1.0 1.07903 stratum pyramidale of rostral CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05345 IV, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34304 GTEX-QVUS-0011-R4A-SM-3GAE7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PMC10274973-media-3.xlsx-ST18-Supplementary_Table_18_476_Bonferroni_significant_results_P_2_67_x_10-6_of_gene_based_association_analyses_H-MAGMA_dlPFC_cortical_neurons_for_sensation_seeking_factor_ST18 Rummagene Transcription Factor Associations 2026 1.0 null DOV13 DepMap CRISPR Gene Dependency 1.0 4.37918 culture medium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.254239 TCEAL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58548 GTEX-QDT8-0326-SM-32PL1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.5852 EBV-B cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.641 ORC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29707 KLF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 124.629 GTEX-RU72-1226-SM-2TF6N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 BHLHE22 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.8934 ARSK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0095 TMEM19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2618 RBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78688 TOV-112D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.892319 SAOS-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-TMZS-0226-SM-3DB9N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-XPVG-0926-SM-4B651 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-QDT8-0006-SM-32PL3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 DV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40148 GLI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82064 ZNF709 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53344 GTEX-PX3G-1026-SM-48TZW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PRSS8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28828 PRDX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4375 GTEX-U8T8-0126-SM-3DB94 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 RARRES2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8231 hemoglobinopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.488549 Brain_Hippocampus_Middle Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 2.19494 posterior orbital gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.81394 Reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.929 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67V-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S341-1626-SM-3K2B8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 MOSPD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08974 HCC1954 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.90038 SNTB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21893 MZ in dorsomedial parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.70702 inherited metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.050995 GTEX-WH7G-0926-SM-4LVMJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 KLF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 86.7001 GTEX-S7SE-0011-R2A-SM-2XCDC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 RNF114 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11493 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06736 GTEX-RU72-1326-SM-2TF6T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 496100659_PCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.11178 GTEX-P4PP-2426-SM-3P61L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 MYNN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14695 ZFTA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7907 GTEX-PLZ6-0526-SM-3P61C GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 CAPNS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05712 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RN-01A-12R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5441-01A-01R-1514-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAB29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51244 GSE106661,GSE106665_2_v_3_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-S7SF-0526-SM-3K2BC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 LARP4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69795 GSE195559_3_v_4_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58864 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055457 GTEX-Q2AG-0226-SM-2S1P4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-OIZH-2026-SM-3NB1M GTEx Tissue Sample Gene Expression Profiles 1.0 1.35572 KLF9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 70.6535 HELZ2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34404 COR-L303 COSMIC Cell Line Gene Mutation Profiles 1.0 null HOXC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1613 TPD52L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06997 ventromedial hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.057 MAPKBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37815 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.77857 Acute Myeloid Leukemia_LAML_TCGA-AB-2925-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null P2RX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7402 Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NI-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR2F2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WK11-0526-SM-3NB3O GTEx Tissue Sample Gene Expression Profiles 1.0 0.847577 connective tissue cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.044669 outer CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.064 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.74009 TGBC52TKB DepMap CRISPR Gene Dependency 1.0 2.98576 SEC31B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25044 ZNF425 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99428 NPAS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48831 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70R-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-6407-02B-11R-A36H-07,TCGA-DU-6407-02A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.656 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R9-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null frontal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -3.31006 Prostate adenocarcinoma_PRAD_TCGA-G9-6498-01A-12R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZBTB7C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.7251 VZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33388 GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 2.49765 PIK3CD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24736 zona incerta, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36745 GTEX-TSE9-0426-SM-3DB81 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-S7SE-0526-SM-2XCD8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 MED25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19443 GTEX-NL3H-0006-SM-2I3FW GTEx Tissue Sample Gene Expression Profiles 1.0 0.849111 GTEX-XQ3S-0426-SM-4BOOA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 22RV1 COSMIC Cell Line Gene Mutation Profiles 1.0 null KMT2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96041 GTEX-XUYS-0226-SM-47JX1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 primary bacterial infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042702 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 2.00098 ZNFX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19589 tail of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.997453 C21orf91 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.399 MAN1B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82251 GTEX-RWS6-2026-SM-2XCB5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null ALPK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.75942 BRAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25229 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040641 cardiovascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.538209 Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ANG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04961 Lung adenocarcinoma_LUAD_TCGA-78-7166-01A-12R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral septal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17988 GTEX-XXEK-1626-SM-4BRUZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PMEPA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66341 ZBTB45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17395 GTEX-RWSA-2026-SM-47JX8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.38272 periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33797 CARMIL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05381 GTEX-X585-0011-R11B-SM-46MUZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.00632 DMRT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7295 HCC202 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40133 GTEX-RM2N-0726-SM-48FD5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 A253 DepMap CRISPR Gene Dependency 1.0 2.35917 GTEX-UTHO-0011-R2A-SM-3GIKC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 STARD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29109 interstitial lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.077874 CTDK-1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.354 CALHM6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44369 GTEX-TKQ1-0526-SM-4DXTG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 NSUN5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90969 GTEX-RVPU-0005-SM-2TF6L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 OVCA420 DepMap CRISPR Gene Dependency 1.0 2.78677 KMOE-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-T5JW-0426-SM-4DM7M GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 UBE2T CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20142 NUDT15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91859 GTEX-WHSE-0011-R11A-SM-3P5YY GTEx Tissue Sample Gene Expression Profiles 1.0 1.16682 GTEX-WFON-1826-SM-3GILG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-REY6-0005-SM-2TF54 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042648 SARS-CoV_84Hour_23935999_GSE47962 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.05725 GTEX-RN64-1226-SM-2TC6E GTEx Tissue Sample Gene Expression Profiles 1.0 1.1748 BT549 CCLE Cell Line Gene CNV Profiles 1.0 1.59896 GTEX-U4B1-1426-SM-4DXTX GTEx Tissue Sample Gene Expression Profiles 1.0 1.36364 ASPC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.892319 Kidney Chromophobe_KICH_TCGA-KL-8346-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.079688 VPS13A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53843 SP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.45694 solitary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.2328 KDM5B ENCODE Transcription Factor Targets 1.0 null Posterior midgut TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.692 GTEX-P78B-0726-SM-2S1O2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 SGF29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3686 MYOZ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.59066 GTEX-QCQG-1926-SM-2S1PI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-QVUS-0226-SM-3GIJY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 TMED8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09729 GTEX-PWCY-1326-SM-48TCU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ITGA2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31226 Hypertriglyceridemia HuGE Navigator Gene-Phenotype Associations 1.0 null EPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96055 CTXN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51411 fallopian tube GTEx Tissue Gene Expression Profiles -1.0 -1.00669 DCBLD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02665 Kidney renal papillary cell carcinoma_KIRP_TCGA-WN-A9G9-01A-12R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GOLGA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56514 Lung adenocarcinoma_LUAD_TCGA-44-A47G-01A-21R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null bone marrow TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060269 connective tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052226 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A7D0-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-62-A471-01A-12R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Epimastigote TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.514 GTEX-XQ3S-0526-SM-4BOQA GTEx Tissue Sample Gene Expression Profiles 1.0 0.852687 SOX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.9985 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70W-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57247 OCI-AML2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.915719 Antral mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.89 GTEX-REY6-2126-SM-48FD9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13413 GTEX-QDT8-0011-R3A-SM-32PKR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 C2orf15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92296 anemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.105844 GTEX-S95S-1426-SM-2XCDM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02667 RAB42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43168 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2IP-01A-11R-A180-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BAIAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18498 hemolytic anemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.186811 Gastric antrum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.804 inferior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.40398 Prostate adenocarcinoma_PRAD_TCGA-WW-A8ZI-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STBD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78429 GTEX-NFK9-1326-SM-3LK5I GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PIK3R4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99065 TACSTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77875 ZBTB7B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2265 ZNF708 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4488 GTEX-Q734-0226-SM-48U1A GTEx Tissue Sample Gene Expression Profiles 1.0 0.873189 culture condition:antigen-presenting cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.705993 NR1H2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49554 GTEX-UPK5-2026-SM-4JBIM GTEx Tissue Sample Gene Expression Profiles 1.0 1.43742 SW1417 CCLE Cell Line Gene CNV Profiles -1.0 -1.7067 GTEX-XBED-0126-SM-47JY7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 H2731 COSMIC Cell Line Gene Mutation Profiles 1.0 null LC-2-AD COSMIC Cell Line Gene Mutation Profiles 1.0 null pigment granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.366623 NR3C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6568 GTEX-PWN1-2026-SM-48TD9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 SLC26A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.05019 melanocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.469987 Endometriosis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.929 HCC366 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10527 UNC93B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11127 Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HI-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RBMY1A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.091 megakaryoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.13889 GCIY COSMIC Cell Line Gene Mutation Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.757 GTEX-X4EO-2726-SM-4E3HS GTEx Tissue Sample Gene Expression Profiles 1.0 1.24969 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34983 intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 MDAMB361 CCLE Cell Line Gene CNV Profiles -1.0 -1.48179 GTEX-X638-0326-SM-47JY1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Sarcoma_SARC_TCGA-DX-A240-01A-32R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PC3 CCLE Cell Line Gene CNV Profiles -1.0 -1.69688 GTEX-RUSQ-0626-SM-2TF5V GTEx Tissue Sample Gene Expression Profiles 1.0 0.859465 GTEX-RVPV-0011-R5A-SM-2TF69 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15612 GTEX-XUJ4-1826-SM-4BOOU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 LMBR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23871 granulation tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.360782 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.46921 HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3493 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45R-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.047618 hematopoietic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.50275 RCHY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60952 GSE182185_0_v_1_pstk_human RummaGEO Gene Perturbation Signatures 1.0 null COPE CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87667 USP36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18696 HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04887 GTEX-RVPU-0011-R5A-SM-2XCAD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-R53T-0326-SM-48FEC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-REY6-0826-SM-2TF4S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 RAB5IF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09202 NCIH209 CCLE Cell Line Gene CNV Profiles 1.0 2.1826 GTEX-XXEK-1126-SM-4BRUX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PTP4A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26814 GSU CCLE Cell Line Gene CNV Profiles 1.0 1.62246 GSU DepMap CRISPR Gene Dependency 1.0 4.51318 GTEX-UPK5-0426-SM-3GAEK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 KP-1N COSMIC Cell Line Gene Mutation Profiles 1.0 null RCH-ACV COSMIC Cell Line Gene Mutation Profiles 1.0 null ING1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61736 APOA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81109 Adductor TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.799 SLC16A11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.31552 Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X585-1226-SM-46MW7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.23563 ZNF155 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.07716 GTEX-PVOW-1626-SM-48TC9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-RWS6-0826-SM-47JXF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 THRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 75.0081 Laryngotracheitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.161 blood vessel TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.561644 ZBTB41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15703 GTEX-NL3H-0011-R11A-SM-2I3E6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.2347 Prostate disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.656 GTEX-QESD-0626-SM-2I5G4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4 Rummagene Transcription Factor Associations 2026 1.0 null melanoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.199356 peritoneal exudate TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.436438 GTEX-SUCS-0226-SM-32PLQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.916495 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5436-01A-01R-1514-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SPARC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.43192 HMGXB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70038 PPP2R5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.13519 DDX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8463 Lung adenocarcinoma_LUAD_TCGA-MN-A4N1-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NKX2-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6336 Brain Lower Grade Glioma_LGG_TCGA-DH-A66D-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.048346 GTEX-W5X1-2626-SM-4LMI8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GNG12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.54183 FBXO34 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85773 hela HPA Cell Line Gene Expression Profiles 1.0 1.44603 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5361-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE198982,GSE198986_1_v_2_daunorubicin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-PX3G-0926-SM-48U12 GTEx Tissue Sample Gene Expression Profiles 1.0 0.976358 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null KURAMOCHI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2269 HCC1599 CCLE Cell Line Gene CNV Profiles -1.0 -1.40279 ZNF77 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92851 GTEX-XV7Q-2226-SM-4BRVY GTEx Tissue Sample Gene Expression Profiles 1.0 0.892074 WSB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42476 Lung squamous cell carcinoma_LUSC_TCGA-56-8628-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NL3H-0011-R7a-SM-2I3G5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.00471 GTEX-OOBJ-0926-SM-48TDO GTEx Tissue Sample Gene Expression Profiles 1.0 1.37394 KMS27 DepMap CRISPR Gene Dependency 1.0 4.14536 ZNF675 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.808 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IFI6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23465 RORB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81535 GTEX-XAJ8-1126-SM-47JYA GTEx Tissue Sample Gene Expression Profiles 1.0 0.968887 GTEX-XGQ4-2526-SM-4AT57 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 NCI-H2198 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.906981 NHLRC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20928 SIX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91708 ZNF223 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90007 GTEX-X8HC-0626-SM-4E3HQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.825293 MTX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5489 GTEX-VUSH-0008-SM-47JWK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-TSE9-0126-SM-3DB83 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 MBIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1744 Merozoite TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.843 blood vessel GTEx Tissue Gene Expression Profiles -1.0 -0.866891 GTEX-RN64-1026-SM-48FDX GTEx Tissue Sample Gene Expression Profiles 1.0 0.943648 GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.54588 GTEX-R3RS-0726-SM-3GIJR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ZKSCAN5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 83.4196 MZ in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.903666 capan2 HPA Cell Line Gene Expression Profiles -1.0 -0.826749 PGAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25147 NDUFV3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85668 ZNF639 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01076 GTEX-OXRP-0526-SM-2I3EW GTEx Tissue Sample Gene Expression Profiles 1.0 1.14826 GTEX-WEY5-0226-SM-3GIKN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 CPZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39658 GTEX-SNOS-0826-SM-4DM5N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.91574 SU-DHL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32771 BRCC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79091 GTEX-QV31-1426-SM-2S1QD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 MV-4-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00092 PANO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81654 GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 2.18773 PANC 08.13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10573 amastigote TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.571619 ELK1::SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 60.4029 ZNF80 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60566 GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.65356 GTEX-XOT4-1126-SM-4B66E GTEx Tissue Sample Gene Expression Profiles 1.0 0.948369 ADCYAP1R1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16251 EMX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.12962 layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.27016 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MH-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLIRP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44164 inner CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08625 EN COSMIC Cell Line Gene Mutation Profiles 1.0 null FTO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.44288 GTEX-XUW1-0226-SM-4BOOS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-WL46-0726-SM-3LK5Z GTEx Tissue Sample Gene Expression Profiles 1.0 0.965335 cuneus, right, peristriate Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.1347 medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.03906 RCN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00088 TRMT12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37372 outer CP in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.834939 GTEX-QDT8-0626-SM-48TYW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Methylmalonic acidemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.249 TBC1D16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32665 superior colliculus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.888865 GTEX-O5YT-1826-SM-32PK9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ZNF768 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9551 MZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.839896 GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 2.16096 GTEX-WFG8-2226-SM-3GIL9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Liver hepatocellular carcinoma_LIHC_TCGA-BD-A2L6-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 1.65076 GTEX-QVJO-0011-R9A-SM-2S1QH GTEx Tissue Sample Gene Expression Profiles 1.0 0.952534 496100319_HIP_no dementia_TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.11082 GTEX-VJYA-1326-SM-3GIJC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 1.80897 SYTL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16502 integral component of membrane GO Cellular Component Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-A75L-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null P3H1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45626 ZSWIM8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46811 Acute Myeloid Leukemia_LAML_TCGA-AB-2869-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SNOS-1726-SM-32PLN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 NMT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.23488 TMEM221 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31419 GTEX-TMMY-1526-SM-4DXST GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.656 GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 2.87719 GTEX-X4XY-0626-SM-4E3IN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 MAFK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.289 ZNF846 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5185 MAPKAPK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.24834 GTEX-P44H-0006-SM-2XCFB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ZBED1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40533 Lung adenocarcinoma_LUAD_TCGA-L4-A4E6-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null musculoskeletal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043825 GTEX-RM2N-0006-SM-2TF5H GTEx Tissue Sample Gene Expression Profiles 1.0 1.12974 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A194-01A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRKACB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76862 KCNG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58748 STAT3 JASPAR Predicted Transcription Factor Targets 1.0 null Overnutrition DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.95 YBX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55276 YARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09631 TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC ChEA Transcription Factor Targets 2022 1.0 null GTEX-OOBJ-0526-SM-48TDK GTEx Tissue Sample Gene Expression Profiles 1.0 1.25727 GTEX-OXRP-0926-SM-48TC1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.941784 GTEX-T2IS-2626-SM-32QPP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 TIAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21924 KCNK12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95026 Uterine Carcinosarcoma_UCS_TCGA-N9-A4PZ-01A-22R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PE-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null WDR91 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.56371 E2F3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9941 GTEX-S3XE-1726-SM-3K2AM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-SIU7-0006-SM-2XCE6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.847994 GTEX-RWSA-0826-SM-2XCBF GTEx Tissue Sample Gene Expression Profiles 1.0 0.836378 GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 2.49651 PPARD JASPAR Predicted Human Transcription Factor Targets 2025 1.0 61.4484 MTA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73974 ATP2C1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63439 POLR2A_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LU99 CCLE Cell Line Gene CNV Profiles -1.0 -1.4627 Lung adenocarcinoma_LUAD_TCGA-97-8172-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial parabrachial nucleus,right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36875 GTEX-UJMC-2026-SM-3GADR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 TAF1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79062 GTEX-RWSA-0126-SM-2XCBB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-XYKS-1626-SM-4BRUQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ME-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.972229 PPIA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11997 GTEX-PX3G-0008-SM-48U2L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-W5X1-0006-SM-3GIJZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.01873 GTEX-P4PP-1826-SM-2S1NT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 KIAA1191 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.27531 KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null layer III of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.24744 GTEX-WHSE-2926-SM-3NMBG GTEx Tissue Sample Gene Expression Profiles 1.0 1.21604 CCDC50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51726 LRP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97296 MEAK7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67826 GTEX-POMQ-2126-SM-2S1OJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-SSA3-0226-SM-32QPN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 KLF5 JASPAR Predicted Transcription Factor Targets 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAL-85-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16479 TBC1D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49683 VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.39694 GTEX-RUSQ-1826-SM-2TF6E GTEx Tissue Sample Gene Expression Profiles 1.0 0.961674 CDCA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2292 PTCH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91041 KCL-22 COSMIC Cell Line Gene Mutation Profiles 1.0 null PPARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 51.6874 parahippocampal gyrus, left, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.826539 MOB3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56753 HMGB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11614 DYNLT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45842 periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.75148 PRDM9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 202.165 GTEX-R55E-0011-R5A-SM-2TC5N GTEx Tissue Sample Gene Expression Profiles 1.0 0.836095 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25019 GTEX-WFG7-2426-SM-3GIL2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 SLC25A46 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83538 GSE145990_1_v_4_ibrutinib_human RummaGEO Drug Perturbation Signatures -1.0 null USP24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02449 DUSP11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95905 MTG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45037 GTEX-UJMC-0005-SM-3GACU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PPARG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83096 GTEX-NFK9-1126-SM-3LK78 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Prostate adenocarcinoma_PRAD_TCGA-HC-8260-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE236502_2_v_3_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null Ehlers-Danlos syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.0 UKE-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.58769 Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KO-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100514_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.28177 FAM217B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48737 HCC70 CCLE Cell Line Gene CNV Profiles -1.0 -3.20997 cuneiform nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.46587 PFEIFFER Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.896599 TEPSIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89934 GTEX-RWS6-1026-SM-47JXD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null midbrain reticular formation, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.985882 membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04982 HCC1171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.939343 SEPHS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54732 GTEX-WI4N-1126-SM-3LK7Q GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 SPTBN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08884 H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.961808 GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 2.14575 GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 1.69201 medial parabrachial nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.908372 GTEX-VUSG-1026-SM-4KKZN GTEx Tissue Sample Gene Expression Profiles 1.0 1.06005 pituitary GTEx Tissue Gene Expression Profiles 1.0 0.827485 TRMO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94743 KYSE-410 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-85-A510-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZH-0926-SM-4DXU4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15865 GTEX-PSDG-0626-SM-2S1OE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-RVPU-0011-R1A-SM-2XCAI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 CZIB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46551 alveolar macrophage TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.841188 outer CP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.874217 CDO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48134 GSE195559_8_v_4_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-T2IS-1926-SM-4DM74 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0648 normocytic anemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.184128 Lung squamous cell carcinoma_LUSC_TCGA-33-4589-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Fetal_Brain_Female Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 1.46018 VGF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67957 H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WEY5-2126-SM-3GILK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-PSDG-0005-SM-3GADC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 3.2178 Lung squamous cell carcinoma_LUSC_TCGA-39-5040-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A24D-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 1.61846 MTARC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78623 496100539_HIP_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.2148 IL18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21692 olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10703 ZFAND5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60405 RAD23B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77434 PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2837 Asynchronous muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.065 TECPR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20374 EHD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21695 Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RC-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XBEC-1226-SM-4AT65 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13006 SG in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.59002 NCI-H2804 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.906981 ZNF260 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67873 SW1116 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XGQ4-0926-SM-4AT4U GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 FYN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25731 U2AF1L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06644 VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.12486 Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KNDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67776 Lung adenocarcinoma_LUAD_TCGA-MP-A4SY-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2814 CCLE Cell Line Gene CNV Profiles -1.0 -1.79844 GTEX-QVUS-0426-SM-48FE3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Prostate carcinoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.656 vascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.541773 vascular smooth muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.229032 TADA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69897 GTEX-RVPU-2326-SM-2TF6R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Lung squamous cell carcinoma_LUSC_TCGA-56-7822-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.740503 ZNF883 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8094 GTEX-U412-0226-SM-3NMC8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UN-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2986-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFON-0526-SM-4LVLY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-R55D-0926-SM-3GAEU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-XUYS-0126-SM-47JWZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 MYC ENCODE Transcription Factor Targets 1.0 null Mesothelioma_MESO_TCGA-MQ-A4LV-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-86-8674-01A-21R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T5JC-0226-SM-32PMA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 SMZ1 DepMap CRISPR Gene Dependency 1.0 2.67144 SJSA1 CCLE Cell Line Gene CNV Profiles 1.0 1.37551 GTEX-O5YU-0008-SM-4E3I7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 DVL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11516 496100443_HIP_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.04662 L1236 DepMap CRISPR Gene Dependency 1.0 2.02412 GTEX-U4B1-0726-SM-4DXUA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-T6MN-0826-SM-32PM4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.990807 GSE196117_1_v_0_clarithromycin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-R55E-1326-SM-48FCR GTEx Tissue Sample Gene Expression Profiles 1.0 0.883706 GTEX-VJYA-1126-SM-3GIJU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MI-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XPVG-1326-SM-4B65P GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 epidermal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.312957 POU5F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52164 CAL 54 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.892319 496100369_PCx_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.10508 GTEX-QXCU-0926-SM-48FEP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 TYK-NU.CP-R Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.19157 PPP1R16A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64018 GTEX-XBEC-0006-SM-4AT5T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GOLGA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02584 KAT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04612 GTEX-RWSA-1126-SM-2XCAZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-WH7G-0626-SM-4LVMO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Lung squamous cell carcinoma_LUSC_TCGA-52-7811-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PLS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.30056 RECQL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0363 JHH-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.90038 triglycerides GAD Gene-Disease Associations 1.0 null SMYD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22957 MBD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59395 NOL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 5.9248 DQX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37902 OARD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53019 A-CA-04-2009(H1N1)_6Hour_23935999_GSE47961 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.64426 GTEX-OIZG-1026-SM-3LK5X GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A3Y1-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RNOR-1326-SM-48FDE GTEx Tissue Sample Gene Expression Profiles 1.0 0.964924 Triglycerides GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.752288 GTEX-P44H-0226-SM-2XCEU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MB-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IKZF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7125 GTEX-QCQG-2126-SM-2S1P8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-OXRK-0008-SM-3NB28 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06243 KLF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 77.4281 SH3BGRL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52884 NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.48072 Lung adenocarcinoma_LUAD_TCGA-86-8673-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CDA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55352 GTEX-PSDG-1126-SM-2S1ON GTEx Tissue Sample Gene Expression Profiles 1.0 1.06125 MINDY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99218 LOX-IMVI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02585 KCNH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12246 THRA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.78587 USP39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44717 GTEX-Q734-0726-SM-48TZP GTEx Tissue Sample Gene Expression Profiles 1.0 0.8837 Antropyloric mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.886 Lateral sinus thrombosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.256 THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40148 GTEX-PLZ5-2026-SM-2S1O4 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-WL46-3026-SM-3LK7Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.13989 TAC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21137 GTEX-T5JW-0726-SM-4DM6D GTEx Tissue Sample Gene Expression Profiles 1.0 0.86331 NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40148 stratum spinosum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.108212 496100669_FWM_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.11475 ZNF667 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9755 PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-h-Classification_of_camel_SON_basal_genes_-_transporters_SON Rummagene Transcription Factor Associations 2026 1.0 null hematopoietic stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.133217 MAGEL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63785 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040448 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null TBL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43888 GTEX-PLZ4-0006-SM-2S1NY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 granular layer of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.989734 MAZ JASPAR Predicted Human Transcription Factor Targets 2025 1.0 87.6116 GTEX-RU1J-0006-SM-2TF6M GTEx Tissue Sample Gene Expression Profiles 1.0 1.34257 ZNF530 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 71.6318 HDAC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1341 RGPD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34455 SUCLG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65753 GTEX-QLQ7-1926-SM-2S1R6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-N7MS-0011-R4a-SM-2HMKW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 trunk TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053507 ATG2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36048 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DE-01A-22R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22934 GTEX-QEG5-0626-SM-2S1PP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ZNF502 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71715 H1-6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17819 cytoplasmic vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.06736 cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042076 Adrenocortical carcinoma_ACC_TCGA-OR-A5JK-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.045587 ZNF860 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78424 GTEX-XGQ4-1826-SM-4AT6F GTEx Tissue Sample Gene Expression Profiles 1.0 0.849682 Prostate adenocarcinoma_PRAD_TCGA-KK-A7AV-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null protein-carbohydrate complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.763162 GTEX-U3ZH-2026-SM-3DB78 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 DDX11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5195 BRD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81121 GTEX-RWS6-0226-SM-2XCA9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-QLQ7-0826-SM-447B3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-QMR6-1326-SM-32PLB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5435-01A-01R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RL DepMap CRISPR Gene Dependency 1.0 2.26103 SP1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PHF19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63966 GTEX-WFG8-0726-SM-3GILP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 lateral subdivision of area 9 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.964347 PNLDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.26141 IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.83056 Lung adenocarcinoma_LUAD_TCGA-50-5930-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEIS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.70747 AGO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34029 Lung squamous cell carcinoma_LUSC_TCGA-39-5028-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X3Y1-2026-SM-3P5YM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-T5JW-1326-SM-4DM5G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-PWN1-1826-SM-2S1PE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 pyramidal layer of caudal subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05297 GTEX-WFG8-2126-SM-3GIKQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-WEY5-1026-SM-4LMK9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 CTAGE9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42332 GTEX-TMMY-1026-SM-4DXTI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 KLF17 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 66.0168 SCARB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99134 SRMS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54682 GTEX-UPIC-0926-SM-4IHLV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-S4P3-1626-SM-3K2AZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 LYL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null CTRL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56373 CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.58864 NUGC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07689 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B0-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94226 Cardiovascular Diseases HuGE Navigator Gene-Phenotype Associations 1.0 null GTEX-XQ3S-1026-SM-4BOPJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.23085 GTEX-U8XE-2526-SM-4E3IT GTEx Tissue Sample Gene Expression Profiles 1.0 1.18253 Brain morphology (MOSTest) GWAS Catalog SNP-Phenotype Associations 2025 1.0 2.5301 LGR4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36066 GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.69317 MSH4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73552 Lung adenocarcinoma_LUAD_TCGA-05-4432-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null principal sensory nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31975 GTEX-WHPG-0826-SM-3NMBF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.982458 precommissural nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07095 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02667 TRPT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10458 8p23 1 copy number variation syndrome WikiPathways Pathways 2024 1.0 null UBE2O CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8098 LS-123 COSMIC Cell Line Gene Mutation Profiles 1.0 null MAF::NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.4743 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X5EB-1826-SM-4E3K8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06988 KML1 DepMap CRISPR Gene Dependency 1.0 5.5118 PUSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40921 GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.67484 GTEX-RNOR-0011-R4A-SM-3GAD3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 HUPT4 DepMap CRISPR Gene Dependency 1.0 21.1141 ATN-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-WOFM-0005-SM-3MJF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 RNASE8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52407 marrow cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.143711 GTEX-Q2AI-0626-SM-48TZU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ENTPD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4305 MCAS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.97309 NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02099 GTEX-X261-0926-SM-3NMCY GTEx Tissue Sample Gene Expression Profiles 1.0 0.839665 PMC11096100-41588_2024_1714_MOESM3_ESM.xlsx-ST18-Unnamed_1_ST18 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-X4EO-0926-SM-3P5Z2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02396 Lung adenocarcinoma_LUAD_TCGA-55-6968-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WH7G-0726-SM-3NMBM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 kaposi's sarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.295132 GTEX-R55C-0005-SM-3GAE9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-RWS6-0526-SM-4GIAJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 KDM4D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04613 GTEX-V955-1826-SM-4JBIL GTEx Tissue Sample Gene Expression Profiles 1.0 1.40181 GTEX-Q2AG-1026-SM-33HBW GTEx Tissue Sample Gene Expression Profiles 1.0 1.15842 central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.3047 BE2M17 DepMap CRISPR Gene Dependency 1.0 3.34842 MIF4GD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29219 DPH6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59607 JUN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.43524 IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.11506 FAM161A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29615 GTEX-TMMY-0726-SM-33HBE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-PLZ4-0008-SM-48TE6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 FZD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87516 NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.907268 ZFYVE19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86816 GTEX-WI4N-1026-SM-3LK7N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 1.40977 PRSS50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89655 C17orf49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23116 PKDCC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03562 HCC202 CCLE Cell Line Gene CNV Profiles -1.0 -1.45488 inner CP in (rostral) midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.987315 GTEX-W5X1-0826-SM-3GILN GTEx Tissue Sample Gene Expression Profiles 1.0 1.13974 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JD-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-Q2AH-0226-SM-48U1I GTEx Tissue Sample Gene Expression Profiles 1.0 0.911798 u87 HPA Cell Line Gene Expression Profiles -1.0 -0.826749 GTEX-XMK1-1126-SM-4IHJ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 CDC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06286 SW 480 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12117 SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.850834 GTEX-V955-1726-SM-4JBHF GTEx Tissue Sample Gene Expression Profiles 1.0 1.03266 lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.050857 GTEX-QVJO-0011-R10A-SM-2S1QJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-WRHU-0926-SM-4E3IG GTEx Tissue Sample Gene Expression Profiles 1.0 1.02467 ETV6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.1523 GTEX-T8EM-0526-SM-4DM64 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A110-11A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF780B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69953 membrane-bounded vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.06736 ECSCR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59844 GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.5346 ZNF682 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.3885 GTEX-PWN1-0126-SM-2I3FK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Fatty acid elongase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.651 lipid metabolism disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.227988 Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null blood platelet TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.232317 GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 1.59952 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.929 Brain Lower Grade Glioma_LGG_TCGA-DU-6392-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6024-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100657_FWM_probable Alzheimer's disease_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.10675 BT-20 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10573 monocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.162992 HOUAI DepMap CRISPR Gene Dependency 1.0 2.61153 POU2F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72606 GTEX-R55F-0126-SM-48FCK GTEx Tissue Sample Gene Expression Profiles 1.0 0.870242 H3K9me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A5TW-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ABCC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.71318 MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.0286 KIF18B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11651 RBM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78905 PPT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92715 PGAM5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82824 SPI1 ChEA Transcription Factor Targets 1.0 null GTEX-R55D-1426-SM-48FEN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Lung squamous cell carcinoma_LUSC_TCGA-43-A56V-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-Q734-2026-SM-3GADA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-XOTO-0226-SM-4B66H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-TKQ2-1226-SM-4DXSV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 tonsil TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.263327 NUP43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5868 outer CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43584 GTEX-U4B1-0926-SM-4DXUV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 FNDC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.40688 GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.84949 NCI-H1770 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-T5JW-1826-SM-3GAE1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF Rummagene Transcription Factor Associations 2026 1.0 null H2BW2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.15502 GTEX-WEY5-1126-SM-4LMIE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Breast_Myoepithelial_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.95906 Lung adenocarcinoma_LUAD_TCGA-55-8514-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TSE9-0526-SM-3DB7Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-SJXC-1226-SM-4DM78 GTEx Tissue Sample Gene Expression Profiles 1.0 0.934221 PMC7849364-supp_gad.342378.120_Supplemental_Table_S4_.xlsx-Hoja1-Table_S4-_SIX2-associated_genes_identified_by_CUT_RUN_overlapping_with_differential_expression_by_SIX2_knockdown_SIX2 Rummagene Transcription Factor Associations 2026 1.0 null FAM98A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18569 SLC29A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52274 GTEX-XQ3S-1226-SM-4BOPP GTEx Tissue Sample Gene Expression Profiles 1.0 1.24579 GTEX-XUJ4-0005-SM-4BOQ6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01734 CDC42EP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04493 PMC11263707-41419_2024_6896_MOESM6_ESM.pdf-67-SIX3-AS1_SIX3 Rummagene Transcription Factor Associations 2026 1.0 null MEIOC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52313 chr8_11330261_C_G_b38 GTEx eQTL 2025 1.0 1.01968 ZNF474 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23856 SNU245 CCLE Cell Line Gene CNV Profiles -1.0 -2.57901 496100467_FWM_probable Alzheimer's disease_no TBI_89_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.10646 GTEX-U3ZN-0526-SM-4DXTH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 MCAS CCLE Cell Line Gene CNV Profiles -1.0 -2.07668 UCK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29716 ARRDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.01839 Diabetes Mellitus, Type 2 HuGE Navigator Gene-Phenotype Associations 1.0 null GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.53303 TRAPPC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20013 Fetal_Intestine_Large Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.65368 GSE148200_3_v_2_gemcitabine_human RummaGEO Drug Perturbation Signatures 1.0 null GMIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88218 limitans nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.898607 Acute Myeloid Leukemia_LAML_TCGA-AB-2840-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-POMQ-1926-SM-3NB1Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-WOFM-1726-SM-3MJFA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-S4Z8-2026-SM-3K2A9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 bj HPA Cell Line Gene Expression Profiles 1.0 0.9508 GTEX-XUJ4-0626-SM-4BOOO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34601 BPHL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27657 GTEX-RU72-0011-R7A-SM-2TF5U GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-P44H-0326-SM-2XCES GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 AKT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73399 Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SNMC-0226-SM-4DM6F GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-REY6-1426-SM-48FDK GTEx Tissue Sample Gene Expression Profiles 1.0 1.06558 BC3C CCLE Cell Line Gene CNV Profiles 1.0 1.48231 type 2 diabetes GAD Gene-Disease Associations 1.0 null GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 2.52308 SRPK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90611 ARL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33745 trypanosomoid form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.337072 SLC27A5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02024 MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0094 spleen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.126972 GTEX-S341-0226-SM-2XCAX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 NCI-H929 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.971335 Brain Lower Grade Glioma_LGG_TCGA-QH-A6CZ-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR1H2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.68 GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.93373 ZBTB7A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.5489 HUP-T4 COSMIC Cell Line Gene CNV Profiles 1.0 2.14311 Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A856-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81V-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ovary HPA Tissue Gene Expression Profiles -1.0 -1.02139 ENSG00000286190 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0636 A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_3Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.57111 CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.870476 TCF25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3753 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-XS-A8TJ-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EHD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14153 POLQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85922 NANOS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56682 GTEX-RU72-0011-R11A-SM-2TF6J GTEx Tissue Sample Gene Expression Profiles 1.0 0.830398 GTEX-WFJO-0005-SM-3GIKY GTEx Tissue Sample Gene Expression Profiles 1.0 0.875092 blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.481259 NR2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1397 GTEX-QVUS-0006-SM-3GAE8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 HNRNPDL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11452 GTEX-XQ3S-2526-SM-4BOOG GTEx Tissue Sample Gene Expression Profiles 1.0 1.467 GTEX-U4B1-0226-SM-4DXU8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Liver hepatocellular carcinoma_LIHC_TCGA-UB-AA0V-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null langerhans cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.25457 EVSAT CCLE Cell Line Gene CNV Profiles -1.0 -1.65928 inner CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28086 GTEX-RNOR-0011-R9A-SM-2TF52 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-QV44-0926-SM-2S1RH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.83537 PLD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80943 Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A7I0-01A-22R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null congenital hemolytic anemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.393374 ACSF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.096 GTEX-P44H-0726-SM-48TBT GTEx Tissue Sample Gene Expression Profiles 1.0 0.963434 Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null G cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.91 SIPA1L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24389 vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.065869 GTEX-RNOR-0426-SM-2TF4U GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 OVCAR-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01286 A-CA-04-2009(H1N1)_0Hour_None_GSE37571 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.27209 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QMR6-0011-R1A-SM-32PKW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 A-Vietnam-1203-2004(H5N1)_7Hour_21865398_GSE28166 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.60085 G140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.835073 NCI-H1155 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40148 MZ in posteroventral (inferior) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.14069 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.242983 F8A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.9238 GTEX-WFON-0326-SM-3GIKX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 VZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16032 GTEX-P4QR-0426-SM-2S1NV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6325-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C15orf40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13896 MMP24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18616 GSE195559_6_v_4_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5977-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NL3H-0011-R2a-SM-2I3GG GTEx Tissue Sample Gene Expression Profiles 1.0 0.917907 GTEX-WVLH-0226-SM-3MJG6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 hsa-miR-511 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Rhoptry COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.149 SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.870963 Reproductive organ cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.656 CTCF_A549_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null peritoneal cavity TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.191728 ESR2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.5766 GTEX-RU72-1026-SM-46MUG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 DLX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98905 ZNF41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99376 H3K9me3_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SRRD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.22713 LITAF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78608 GTEX-REY6-0426-SM-2TF5G GTEx Tissue Sample Gene Expression Profiles 1.0 1.22766 GTEX-XAJ8-0126-SM-47JYG GTEx Tissue Sample Gene Expression Profiles 1.0 1.11244 OSBPL8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5914 GTEX-XMD1-2826-SM-4AT5F GTEx Tissue Sample Gene Expression Profiles 1.0 1.22157 CREB3L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.859 P30-OHK COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-T2IS-0126-SM-4DM6O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 icSARS CoV_0Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.63054 GTEX-R55C-1726-SM-3GADJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 EFO-27 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-OIZF-0006-SM-2I5GQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.941569 MDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44617 ACAD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.3749 GTEX-UPIC-1026-SM-4IHLT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-WVLH-0006-SM-3MJF7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-WFG7-1026-SM-4LMK8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 A-Netherlands-602-2009(H1N1)_30Hour_None_GSE40844 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.32826 GTEX-X8HC-0126-SM-4E3JW GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ZSCAN10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.31775 MYD88 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77831 ZNF362 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46028 E2F1 JASPAR Predicted Transcription Factor Targets 1.0 null NIHOVCAR3 DepMap CRISPR Gene Dependency 1.0 3.76535 GTEX-R45C-0006-SM-3GAD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Pancreatic adenocarcinoma_PAAD_TCGA-H8-A6C1-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YR-01A-12R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLF15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 92.1252 CERK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.13949 NCIH2023 CCLE Cell Line Gene CNV Profiles 1.0 2.3467 PMC5130036-oncotarget-07-40690-s006.csv--AR_signature_for_GSEA_AR Rummagene Transcription Factor Associations 2026 1.0 null GTEX-PWN1-0626-SM-48TDT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Male reproductive organ cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.656 TCTA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85352 SNU620 CCLE Cell Line Gene CNV Profiles 1.0 1.41817 GTEX-X5EB-0006-SM-46MV5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-PX3G-2426-SM-48TZZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ZNF580 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.47541 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null SAP130 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74503 GTEX-SN8G-0006-SM-32PLD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-W5X1-2526-SM-3GILC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ZNF551 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73601 WM88 CCLE Cell Line Gene CNV Profiles -1.0 -1.37958 EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38301 blast cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.131842 HLF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21211 GTEX-T2IS-1026-SM-32QP1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PROCA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85179 EDRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84817 IZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09278 Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P4PP-3026-SM-3P61O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PAX5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-PW2O-0126-SM-48TC8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18279 GTEX-PWOO-2526-SM-2S1PG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GSE184087_2_v_1_tert_human RummaGEO Gene Perturbation Signatures -1.0 null SPI1-20517297-HL60-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null C5orf24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33459 Prostate adenocarcinoma_PRAD_TCGA-XJ-A83G-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Crus I, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.46734 lymph node HPA Tissue Gene Expression Profiles 1.0 1.58903 GTEX-RM2N-0008-SM-48FF3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-R55D-1826-SM-48FEF GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 HCC12 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40148 SP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.996508 ATPase dependent transmembrane transport complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.006 MPHOSPH8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.34697 vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.57097 GTEX-QXCU-0126-SM-2TC5Q GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21205 GTEX-UJHI-0326-SM-4IHJE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 UBE2NL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6385 GTEX-OIZH-3026-SM-3NB1G GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GSE151612_4_v_2_pracinostat_human RummaGEO Drug Perturbation Signatures 1.0 null MEG01 CCLE Cell Line Gene CNV Profiles 1.0 1.55 GTEX-U3ZN-0626-SM-3DB7U GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-SIU8-0426-SM-4BRUE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XQ3S-0006-SM-4BOQ4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.12084 GTEX-T5JC-0005-SM-4DM7B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-R55G-0826-SM-2TC5U GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 FU97 COSMIC Cell Line Gene Mutation Profiles 1.0 null LIMD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27188 PIP4K2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.555 UFC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32422 OVOL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26763 NPIPB11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12422 GTEX-XUJ4-1326-SM-4BOQ9 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 MAP4K4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58107 GTEX-VJWN-0126-SM-3GIK7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 anterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.947269 SNU61 CCLE Cell Line Gene CNV Profiles -1.0 -1.50052 KDM5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40401 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 1.87333 GTEX-SUCS-1426-SM-4DM5W GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 familial combined hyperlipidemia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.585108 HCC1171 CCLE Cell Line Gene CNV Profiles -1.0 -1.98218 GTEX-WZTO-0426-SM-3NM99 GTEx Tissue Sample Gene Expression Profiles 1.0 1.39677 PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4 Rummagene Transcription Factor Associations 2026 1.0 null H3K9me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null WSUDLCL2 CCLE Cell Line Gene CNV Profiles 1.0 1.46994 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8041-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WHSB-0326-SM-3LK6K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WM-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-P4PQ-1026-SM-3NMCN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 CAMSAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61598 GTEX-TKQ2-1726-SM-4DXUP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 SNU475 CCLE Cell Line Gene CNV Profiles -1.0 -1.84762 ZNF781 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87941 GTEX-UPJH-0326-SM-3GADU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 lower respiratory tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.049477 496100353_HIP_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.25883 GTEX-UTHO-0011-R1A-SM-3GIJO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Systemic lupus erythematosus GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.509691 DCTD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89637 ventral anterior nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.28094 GTEX-Q2AH-1126-SM-48TZM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-T2IS-0426-SM-32QPE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 CXCL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44312 T-T COSMIC Cell Line Gene Mutation Profiles 1.0 null Respiratory system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.656 caco2 HPA Cell Line Gene Expression Profiles -1.0 -0.826749 GTEX-NFK9-0006-SM-3GACS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 adipose tissue HPA Tissue Gene Expression Profiles -1.0 -1.02139 Pharate pupa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.547 GTEX-S7SE-0011-R4A-SM-2XCDB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-U3ZM-0226-SM-4DXTA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 YIPF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6571 ENDOU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82452 MKS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51677 KURAMOCHI CCLE Cell Line Gene CNV Profiles -1.0 -1.46473 PANC-02-03 COSMIC Cell Line Gene Mutation Profiles 1.0 null SNAI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.20115 SH3BGRL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32959 NR2C2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69322 NCBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95517 Lung squamous cell carcinoma_LUSC_TCGA-56-5898-01A-11R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PLZ4-2726-SM-3P61A GTEx Tissue Sample Gene Expression Profiles 1.0 0.834562 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.18796 GTEX-QVJO-1325-SM-2S1QX GTEx Tissue Sample Gene Expression Profiles 1.0 0.90793 GTEX-T6MN-0526-SM-32PMS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OD-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-S4UY-0006-SM-3K2A7 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-NPJ8-2626-SM-2D7W2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.19131 GTEX-XOT4-1426-SM-4B65T GTEx Tissue Sample Gene Expression Profiles 1.0 1.2107 cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.60263 C6orf132 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84766 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A69I-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KIF1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24426 cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.048512 macrophage TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.610943 Brain Lower Grade Glioma_LGG_TCGA-HT-A74J-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PHRF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15135 CEP120 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65086 NCI-H322T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.961808 lymph node TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.072105 ENOPH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72579 aortic smooth muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.576015 GTEX-V1D1-0226-SM-4JBHG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-RWSA-0726-SM-2XCBE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-UJMC-0526-SM-3GAE3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-SE5C-2126-SM-4BRUJ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 MPZ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65865 MT-CO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55461 GTEX-XUZC-0326-SM-4BOO8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ZNF701 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 61.9981 GLIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 55.6812 laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1613 SUCLG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.81079 RALBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53416 GTEX-WY7C-2526-SM-3NB2N GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PPCS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89705 GTEX-X4EP-0526-SM-3P5YW GTEx Tissue Sample Gene Expression Profiles 1.0 0.951296 GTEX-OHPM-0226-SM-3LK61 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 SLC22A23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67142 GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 1.92522 JHOS4 CCLE Cell Line Gene CNV Profiles -1.0 -2.23102 Prostate adenocarcinoma_PRAD_TCGA-VN-A88N-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QCQG-0526-SM-48U2A GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 SLC2A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47509 GTEX-WEY5-1926-SM-3GIL8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Prostate adenocarcinoma_PRAD_TCGA-M7-A723-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATP5IF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91593 GTEX-QVJO-0011-R5A-SM-2S1QM GTEx Tissue Sample Gene Expression Profiles 1.0 1.1005 TOR1AIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25874 GTEX-RUSQ-0126-SM-47JWV GTEx Tissue Sample Gene Expression Profiles 1.0 1.44895 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17165 MG-63 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02585 Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FAM86C2P CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2546 RT4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13524 cellular_component GO Cellular Component Annotations 2015 1.0 null C4orf36 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65416 lateral parabrachial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.35996 GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.38216 GTEX-OHPK-1326-SM-3MJGN GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-PWN1-2426-SM-48TDD GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 RUNX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1476 GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 2.26662 PAX5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-A494-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CD320 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.99887 GTEX-OXRP-0126-SM-3NB32 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 intracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.050042 CHMP4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22219 IGFLR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7619 TE-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null RERF-LC-KJ Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.34983 Lung adenocarcinoma_LUAD_TCGA-69-A59K-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CCDC115 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20875 GSPT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98969 prostate GTEx Tissue Gene Expression Profiles 1.0 1.52729 CTV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZBTB11 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.8568 H3K9me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-Q2AH-1026-SM-48TZI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-RU72-1126-SM-2TF6H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-PX3G-0826-SM-48TZS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1706 NH-12 COSMIC Cell Line Gene Mutation Profiles 1.0 null Erythrocytic stage TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.786 substantia innominata, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.0501 GTEX-N7MS-0926-SM-2HMIZ GTEx Tissue Sample Gene Expression Profiles 1.0 0.847746 STXBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43956 YY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25131 subthalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.667 GTEX-RUSQ-1026-SM-2TF6V GTEx Tissue Sample Gene Expression Profiles 1.0 1.17953 ETV5::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.0457 CHRNA9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13968 GTEX-SNMC-0526-SM-4DM69 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PUF60 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20379 hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.834204 COLO684 CCLE Cell Line Gene CNV Profiles 1.0 1.70409 MZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.47743 XKR8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99473 SNU-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.849599 Obstructive lung disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.656 myeloid progenitor cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.14212 GTEX-UPIC-0226-SM-3GADO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-XV7Q-2926-SM-4BRUL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Fish- and plant-related diet GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.1699 STRN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89266 NSMCE4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34202 SW1116 CCLE Cell Line Gene CNV Profiles -1.0 -1.47134 DOLPP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23042 MASP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77132 GTEX-Q2AI-1126-SM-48U19 GTEx Tissue Sample Gene Expression Profiles 1.0 0.950127 CCDC61 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90336 GTEX-OIZG-1326-SM-2HMIQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 NFIX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.0252 ZNF69 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62098 GTEX-XV7Q-1426-SM-4BRWA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 SERHL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7542 TMEM43 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28682 IZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1951 GTEX-UTHO-0011-R3A-SM-3GIK8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 melanosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.386979 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T2IS-0926-SM-4DM5B GTEx Tissue Sample Gene Expression Profiles 1.0 1.13583 temporal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.887263 SNAI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.4185 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51627 Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OIZH-0005-SM-2HMJN GTEx Tissue Sample Gene Expression Profiles 1.0 0.923335 STAT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.5839 Lung squamous cell carcinoma_LUSC_TCGA-58-8388-01A-11R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USP25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71062 GTEX-XQ8I-0626-SM-4BOPT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-T6MO-1226-SM-4DM5S GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-WRHU-1326-SM-4E3K7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.27009 Lung adenocarcinoma_LUAD_TCGA-MP-A4T8-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.99154 male reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.052481 NCI-H2023 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.97003 GTEX-TKQ1-1026-SM-4GICL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 lymphoid tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055324 COLO-704 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11835 CFLAR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37876 ZNF730 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0564 GTEX-VJYA-0426-SM-3GIJK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 POLR1H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22536 SOX17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63008 BRD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92459 ZNF257 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 90.3808 ZBTB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49129 GTEX-P4PQ-0626-SM-3NMCU GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-WL46-0426-SM-3TW8J GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-PWN1-1626-SM-2S1OL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-U3ZN-0226-SM-3DB8D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 a549 HPA Cell Line Gene Expression Profiles -1.0 -0.826749 PSN1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71E-01A-31R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXA6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83823 KP-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K9me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null FGF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02616 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40133 TAL1-30185409-K562-MOUSE-BONEMARROW-LEUKEMIA ChEA Transcription Factor Targets 2022 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-8146-01A-11R-2247-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LTF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91972 GTEX-T5JW-1226-SM-3GACY GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-WRHU-1026-SM-4E3ID GTEx Tissue Sample Gene Expression Profiles 1.0 0.911805 GTEX-TSE9-2926-SM-3DB77 GTEx Tissue Sample Gene Expression Profiles 1.0 0.946316 NCI-H446 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZNF483 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16355 APOBEC3H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38172 bacterial infectious disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042276 GTEX-XBEW-1326-SM-4AT63 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.037 B3GNT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44969 SEC23A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34995 RBPJ JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6103 PPARG JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-V955-0126-SM-4JBH5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-XAJ8-0726-SM-47JY5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.830368 H2AB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.8037 HT29 CCLE Cell Line Gene CNV Profiles -1.0 -1.90111 GTEX-R55F-0011-R8A-SM-2TF4F GTEx Tissue Sample Gene Expression Profiles 1.0 1.06035 PAX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64186 L3MBTL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78113 Anterior midgut TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.511 adult stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.108608 GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.7217 GTEX-NPJ8-0011-R11A-SM-2YUMS GTEx Tissue Sample Gene Expression Profiles 1.0 0.891823 GTEX-VUSG-0006-SM-3GIK9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.956346 GT3TKB COSMIC Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-77-7463-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CDY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61273 GTEX-U3ZH-0626-SM-4DXT3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PHH TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.197 496100418_TCx_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.38558 GTEX-S32W-2426-SM-2XCAT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Fetal_Intestine_Small Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -2.02783 GTEX-QEL4-1426-SM-447AC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-XBEW-1526-SM-4AT4K GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 GTEX-XGQ4-1526-SM-4AT6H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.53325 NDOR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70715 KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.19918 GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.80943 GTEX-XBED-1926-SM-47JYP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.40148 MTMR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79309 GTEX-RU1J-0226-SM-2TF5Y GTEx Tissue Sample Gene Expression Profiles 1.0 0.832299 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QEG4-1226-SM-2S1P6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 PMC11906354-41588_2025_2087_MOESM4_ESM.xlsx-ST12-Unnamed_3_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null GSE226355,GSE226357_3_v_4_ybx1_human RummaGEO Gene Perturbation Signatures 1.0 null FAM117A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42889 Lung squamous cell carcinoma_LUSC_TCGA-22-4604-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X62O-2226-SM-46MW3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.2041 globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.25201 ADSS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74564 GTEX-S7SF-0006-SM-3K2B6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 vertebrate muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.068215 PAX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100376_FWM_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.25314 inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12647 NUDT7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70398 Lung adenocarcinoma_LUAD_TCGA-L9-A443-01A-12R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HMGB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.943 TRIM39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60757 GTEX-XV7Q-0126-SM-4BRVK GTEx Tissue Sample Gene Expression Profiles 1.0 1.01134 RNF121 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84807 FOXG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45586 NAMALWA cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.606 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HT-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WH7G-1726-SM-4LVKY GTEx Tissue Sample Gene Expression Profiles 1.0 1.28249 GTEX-SIU7-1826-SM-2XCE2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 NUP58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07763 MDM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10934 GTEX-RTLS-0006-SM-2TF58 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 NCI-H1781 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07689 SMIM26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26325 SS18L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6361 GTEX-RNOR-0005-SM-2TF4Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Fruit consumption GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.804576 EXT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51586 HCC2157 CCLE Cell Line Gene CNV Profiles -1.0 -1.48179 GTEX-T6MN-0011-R9A-SM-32QOZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 SMC1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.24677 GTEX-P4PQ-0008-SM-48TDX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RN64-1826-SM-48FDV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 ZBTB14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.59567 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6962-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null skin TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.397979 FOXJ1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30651 ZNF441 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54866 Lung adenocarcinoma_LUAD_TCGA-NJ-A4YP-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hippocampus minor TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.578 Ring stage TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.825 Brain Lower Grade Glioma_LGG_TCGA-DU-A6S7-01A-21R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.33063 Rectum adenocarcinoma_READ_TCGA-DY-A1H8-01A-21R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SYCP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13939 Acute Myeloid Leukemia_LAML_TCGA-AB-2913-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CG-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WFON-2526-SM-3LK7P GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Lung squamous cell carcinoma_LUSC_TCGA-39-5037-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.46345 BCL7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17247 JHOS-4 COSMIC Cell Line Gene CNV Profiles -1.0 -3.12964 cation-transporting ATPase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.27 QPRT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24094 reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042336 VZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.9643 H3K9me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NAGK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52559 Lung squamous cell carcinoma_LUSC_TCGA-21-1082-01A-01R-0692-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-EI-6507-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RBCK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01482 SVBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72303 Female reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 0.929 ZKSCAN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31822 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-PN-A8MA-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 496100288_HIP_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.11244 Brain Lower Grade Glioma_LGG_TCGA-WY-A85C-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-MR-A8JO-01A-12R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DQ-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null promastigote TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.518465 KALS-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-QMR6-0011-R10A-SM-32PKO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 spleen GTEx Tissue Gene Expression Profiles 1.0 1.30735 GTEX-OXRO-0326-SM-33HBM GTEx Tissue Sample Gene Expression Profiles 1.0 0.923462 dyslipidemias; syndrome GAD Gene-Disease Associations 1.0 null protozoan form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.158528 RP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53666 GTEX-TSE9-1226-SM-4DXTM GTEx Tissue Sample Gene Expression Profiles 1.0 1.21694 ARID5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77137 RLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55566 CASTOR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01382 COLO-783 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44361 NCI-H292 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.84779 GTEX-S4Z8-0006-SM-3K2AQ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 Lung squamous cell carcinoma_LUSC_TCGA-96-A4JK-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PSDG-1026-SM-48TCV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 an3ca HPA Cell Line Gene Expression Profiles -1.0 -0.826749 ANKS1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64123 respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.045594 RXRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 86.7539 KCNA5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93312 GTEX-SNMC-0126-SM-2XCFO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.908327 DANG CCLE Cell Line Gene CNV Profiles 1.0 3.2803 Microneme COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.207