association	dataset	threshold value	standardized value
Adrenocortical carcinoma_ACC_TCGA-OR-A5JE-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF674	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80907
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85462
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.968635
layer 2 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06183
Trophectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.181
TCERG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98092
superficial stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19771
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TFCP2L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86946
glycine transport	GO Biological Process Annotations 2015	1.0	null
LS-174T cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63357
DYRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15694
HCC1187	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.11503
PRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62194
granule cell layer of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44346
organic substance transport	GO Biological Process Annotations 2015	1.0	null
TMCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92803
EMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05728
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04097
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044491
KDM5B_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04236
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05677
NKAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47414
C8166	DepMap CRISPR Gene Dependency	1.0	11.5143
r4 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15623
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14769
L-alanine transport	GO Biological Process Annotations 2025	1.0	null
ZNF503	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98105
ZNF558	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23438
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99582
FOS	ENCODE Transcription Factor Targets	1.0	null
GSE216538_1_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23288
GTEX-XPVG-0526-SM-4B65N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52953
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15122
Lung adenocarcinoma_LUAD_TCGA-91-6829-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UMUC9	DepMap CRISPR Gene Dependency	1.0	5.4125
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34723
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19422
ZNF418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95233
r5 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03429
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
cls1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.577
PDIA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34292
PCDHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06615
ZFYVE27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62777
DPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40446
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56456
Field CA3, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59089
Kidney renal clear cell carcinoma_KIRC_TCGA-T7-A92I-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryonic fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.084972
GTEX-P4PQ-1626-SM-2HMKK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895895
GTEX-R55C-1926-SM-2TF4K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98092
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6331
PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
ELP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58008
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1003
PACSIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76624
endoplasmic reticulum	LOCATE Predicted Protein Localization Annotations	1.0	null
MV411	Achilles Cell Line Gene Essentiality Profiles	1.0	1.8149
hsa-miR-4538	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29411
GTEX-P4QS-1726-SM-3NB1V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86759
MRPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6672
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0868
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.54045
Lung adenocarcinoma_LUAD_TCGA-95-7948-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196699_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Field CA3, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68165
SNU1272	CCLE Cell Line Gene CNV Profiles	1.0	1.46025
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042628
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.79311
Palatine uvula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.099
CELSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61909
PLPP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16145
HIBADH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83565
SNU349	CCLE Cell Line Gene CNV Profiles	1.0	2.89642
anion transport	GO Biological Process Annotations 2015	1.0	null
GSE112174_5_v_7_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40446
NANOG-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25304
apical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.319328
Phagocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.564
RIPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54575
BACH1_02_17	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.80735
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.443
UQCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77524
neutral L-amino acid transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
PCDHB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08163
FDFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2566
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLEKHA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55012
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11199
GTEX-T6MN-0526-SM-32PMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4965
GSE145311_0_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FBXW9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64366
SAP30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91125
BAIAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18498
lateral superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43687
CLDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27842
t70-white-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.41975
hsa-miR-1231	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Far Eastern spotted fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
697	Achilles Cell Line Gene Essentiality Profiles	1.0	1.06081
C1GALT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36855
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37129
GTEX-S7SF-2126-SM-3K2B2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933962
primary auditory cortex (core)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72733
SARAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76214
hsa-miR-4749-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
intellectual disability	HPO Gene-Disease Associations	1.0	null
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.1563
UFSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6208
organic anion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.946142
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.41075
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1237
PLB985	CCLE Cell Line Gene CNV Profiles	1.0	1.35837
LRRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28007
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7332
TMED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12785
PGPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48326
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5288
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77327
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31983
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_1426_OE_Mir10a_ERP106848	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.91115
GSE182680,GSE182683_0_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
UBE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6429
anion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
hindlimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.143535
TSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62746
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.358919
GSE196699_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
neutral amino acid transport	GO Biological Process Annotations 2015	1.0	null
Field CA2, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24982
Hyperopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
NR4A1_02_84	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.27302
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.7075
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16492
BHLHA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53303
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3TX-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1930	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39708
ZNF79	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96694
SWAP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35813
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6131
SLC25A33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.207
SLC7A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85958
Pseudopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.012
GSE179031_0_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34649
AGPAT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80033
PLEKHH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11243
Mr	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.927
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S33H-2326-SM-2XCB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17456
CLBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87709
Entorhinal area, medial part, dorsal zone, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0726
TRIM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19522
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.67683
NEXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47274
CCDC82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24097
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.651
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07035
glycine transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE71491_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74926
GPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48339
Brain Lower Grade Glioma_LGG_TCGA-S9-A7J0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149903_6_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Basal node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.681
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.466
TP53INP2_OE_GDS5054_385_mouse_Muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
r7 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09974
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5039
HTR1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1147
recycling endosome membrane	GO Cellular Component Annotations 2025	1.0	null
NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3295
GSE167886_3_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Developmental and epileptic encephalopathy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MKKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13818
UNC119B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85074
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27746
AR-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9817
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10115
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09624
abnormality of vitamin metabolism	HPO Gene-Disease Associations	1.0	null
ZNF385B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6281
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27245
NCIH1581	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66279
PMC6469946-aav1472_Data_file_S3.xlsx-PPARG_targets_UP_RNA-Seq_Young-Supplemental_Table_3_PPARG_targets_up_regulated_in_dKO_vs_CONTROL_RNA-Seq_Young_FDR_0_1_n_376_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52342
Red bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34558
TTLL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9329
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Central lateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08338
MASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70329
RORC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21168
Paranode region of axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.804
TMPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40155
PTS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96516
SW837	CCLE Cell Line Gene CNV Profiles	1.0	1.54877
vacuolar membrane	GO Cellular Component Annotations 2023	1.0	null
NAP1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64736
nucleus subputaminalis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.949657
NAT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04823
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37161
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.913432
DR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66949
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CUL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04219
extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
NABP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05339
SOX2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE226091,GSE226092_3_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
19286929-SuppTable2h	GeneSigDB Published Gene Signatures	1.0	null
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5772
SCNN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36472
Field CA1, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89496
SLC-mediated transmembrane transport	Reactome Pathways 2024	1.0	null
UBALD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17344
BPHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27657
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.17655
Eustachian tube disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.832
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65821
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.66696
CRX	ChEA Transcription Factor Targets	1.0	null
Hydroxyprolinuria	DisGeNET Gene-Phenotype Associations	1.0	null
LHX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03187
DCAF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51062
ELOVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96544
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SG231	DepMap CRISPR Gene Dependency	1.0	2.47415
Intrinsic component of endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.223
ATP2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55269
OSBPL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65349
Lung adenocarcinoma_LUAD_TCGA-97-A4LX-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2721
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
EIF4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66148
ARHGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42904
renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.407073
chr5_151437000_A_C_b38	GTEx eQTL 2025	1.0	4.3135
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hyperglycinuria	OMIM Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5984-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100411_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28613
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847365
layer 4 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04747
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.917775
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
FBXW11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68006
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33099
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831328
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0011
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.874997
SIX5_02_78	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.29768
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_31_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
STRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89266
increased aggression	MGI Mouse Phenotype Associations 2023	1.0	null
DZIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96722
L-amino acid transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-NFK9-0426-SM-2YUNK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21779
Distal tip cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.609
GTEX-VJYA-1726-SM-3NMDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856297
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.29144
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.842404
Amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
abnormality of the urinary system	HPO Gene-Disease Associations	1.0	null
DUSP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31864
LEF1-29337183-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
SMIM20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05504
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4858
GSE185881,GSE185884_2_v_3_ctcf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47101
proline transmembrane transport	GO Biological Process Annotations 2023	1.0	null
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8696
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14243
Nuclear outer membrane-endoplasmic reticulum membrane network	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
DCAF4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51116
conceptus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.540188
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
autoimmune disease of endocrine system	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.323002
r8 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24162
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1126
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.230409
Endometrial gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
RABIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07103
ADAM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08641
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29128
hsa-miR-1268b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
ERCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60649
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.909
GSE110341_1_v_0_lmna_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22196
glycine transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
Intrinsic component of periplasmic side of cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.532
axon part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.112727
Brown adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.917
NDRG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03107
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0135
Outer membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.621
SURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62805
organelle	GO Cellular Component Annotations 2015	1.0	null
GALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34647
mantle zone of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00357
FLYWCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67985
GSE239578_0_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC2935	DepMap CRISPR Gene Dependency	1.0	2.16516
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ST-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.943
Crohn's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.8699
GSE173873_12_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.08784
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06729
ACP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06333
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.127
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8269
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67746
Perturb_18102_KO_Tbx20_SRP007579	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
precentral gyrus, right, bank of the precentral sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22681
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF850	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75507
GTEX-WZTO-1026-SM-3NM9P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19999
CDK19_knockdown_164_GSE38061	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.31893
RAD21	ChEA Transcription Factor Targets	1.0	null
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.925164
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.11109
SLC-mediated transmembrane transport	Reactome Pathways 2014	1.0	null
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36349
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04234
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
FOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12415
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.912233
Oviductal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.196
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.879048
IQSEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97522
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13724
Perturb_947_KO_Vdr_SRP176410	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.9233
ZNF286A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49656
PU.1-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Plant gall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.927
Recycling endosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
organic acid transmembrane transport	GO Biological Process Annotations 2015	1.0	null
GM2 gangliosidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
NADK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07369
IWS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87039
Nkx2-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7591
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5676-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS79	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62763
TMEM151A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26996
DICER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14569
TMEM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.678
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59652
GTEX-XGQ4-2526-SM-4AT57	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989822
GTEX-TKQ1-1326-SM-4DXU7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16652
monovalent inorganic cation transport	GO Biological Process Annotations 2015	1.0	null
C6orf120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39932
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hydroxyprolinuria	HPO Gene-Disease Associations	1.0	null
GPR120_KO_GDS4830_413_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4626-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Transport of inorganic cations/anions and amino acids/oligopeptides	Reactome Pathways 2024	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE203655_0_v_1_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158100,GSE158101_1_v_0_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
glycine-tRNA ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.055
GSE84148,GSE96938_3_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.842404
Subcutaneous adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.566
MYC	ENCODE Transcription Factor Targets	1.0	null
Perturb_2150_KO_Piezo1/Piezo2_SRP226320	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.34569
RAB31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74313
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AKNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14372
C2CD4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44748
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58852
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99663
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03831
extracellular vesicular exosome	GO Cellular Component Annotations 2015	1.0	null
RNF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49322
TBL1Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52692
intralaminar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20959
GTEX-X638-0326-SM-47JY1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82462
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36896
GSE130217_0_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38198
NT5C3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32989
Roe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.716
SOX3-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848264
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1738
AEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49807
MSH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25366
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48157
STXBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2384
main axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.48005
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44926
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4226
GSE114992,GSE114993_0_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1-21170310-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Ost-alpha/Ost-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.801
KYAE-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TFDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77876
MAFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33692
H3K27me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4453	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GSE193282_3_v_1_cd44_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
TNRC6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22434
AMIGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45537
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88601
Umbilical cord blood cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.551
Hailey-Hailey disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
PHF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82669
Posterolateral visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41478
GTEX-XPVG-2826-SM-4B66J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1488
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.880029
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65981
GSE246195,GSE246305_2_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Endoplasmic reticulum subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Perturb_7086_KO_Srsf5_SRP309981	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.35247
RT112	DepMap CRISPR Gene Dependency	1.0	2.47877
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MP-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
estradiol_homo sapiens_gpl570_gse16683	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43074
Lung adenocarcinoma_LUAD_TCGA-MP-A4T9-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41399
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43811
carboxylic acid transmembrane transport	GO Biological Process Annotations 2025	1.0	null
hsa-miR-548s	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TMEM165	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51301
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7728
MT-CO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81949
Perturb_1692_KO_Prmt5_SRP059561	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.57176
methotrexate_homo sapiens_gpl570_gse11440	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984854
Subdural space	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.866
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
L-alanine transport	GO Biological Process Annotations 2023	1.0	null
Α-METHYL-D,L-TRYPTOPHAN	DGIdb Drug Targets 2026	1.0	13.233
schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.199681
FGF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17104
Petiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
NR0B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7851
endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064604
LRRC61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8798
TXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67179
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
MOSPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.55949
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.91178
CANT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56205
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20978
DIFI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.487886
CINP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22656
GSE119978,GSE180930_2_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.619
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CF-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAV1_KO_GDS3551_366_mouse_mouse heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HDAC3_KO_GDS4886_66_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SVEC4-10 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
CSAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86409
SNX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8629
nitrogen compound transport	GO Biological Process Annotations 2015	1.0	null
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JUN	JASPAR Predicted Transcription Factor Targets	1.0	null
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2091
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55939
GBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48598
proton transmembrane transport	GO Biological Process Annotations 2025	1.0	null
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.838255
PCSK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31487
GSE111102,GSE111105_8_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2656
outer CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.950296
H3K27me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5514
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.863
NCOR-22465074-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EFE184	DepMap CRISPR Gene Dependency	1.0	7.11683
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.978342
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23058
r6 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65738
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10176
GSE111102,GSE111105_1_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234334,GSE234336_1_v_0_zhx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8956
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.880029
BL41	CCLE Cell Line Gene CNV Profiles	-1.0	-2.28863
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
HCC70	DepMap CRISPR Gene Dependency	1.0	2.97188
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8434
PTTG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47744
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.9806
GTEX-X3Y1-2426-SM-3P5Z7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0711
RFX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29898
adiposetissue	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2431
LEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43212
Varicosity	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.73
r4 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00357
GTEX-Q2AG-0626-SM-2S1PV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15665
MFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64608
mantle zone of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17862
SEC24C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15747
PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52089
hsa-miR-450b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
CYB561A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49074
amino acid transmembrane transport	GO Biological Process Annotations 2015	1.0	null
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08775
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886838
DTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94929
Perturb_6330_KO_Lonp1_SRP304502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.06284
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20076
forelimb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.13652
DOT1L_DELETION_GDS4295_427_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells - 5 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88654
post-anaphase microtubule array	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.647
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06247
KIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4704
claw	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.03522
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PDLIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53067
ERLEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63428
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82015
GTEX-WYVS-2426-SM-3NMA9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23586
STAT3_deficiency_GDS3106_58_mouse_type II alveolar cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FN-7833-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE246195,GSE246305_2_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110178_4_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57089
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04202
GSE143994_2_v_3_ythdf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
amino acid transmembrane transport	GO Biological Process Annotations 2023	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.976268
TBX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12984
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5434
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.42224
solute:proton symporter activity	GO Molecular Function Annotations 2025	1.0	null
ANKMY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75607
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.280717
glycine transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
Dentate gyrus, granule cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36424
DPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98231
ASB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5895
urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055447
Typhus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.926
GSE185944_5_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ILF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21798
Lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.863
LYRM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79959
Myotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
Nephrolithiasis	DisGeNET Gene-Disease Associations	1.0	null
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19559
methionine-importing ABC transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.914
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AU565	CCLE Cell Line Gene CNV Profiles	1.0	1.59181
GSE179031_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11544
INPP5K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13974
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Glycoprotein network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.782
ZNF354C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35692
L-amino acid transport	GO Biological Process Annotations 2023	1.0	null
ZNF548	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24361
NUPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57271
DCAF12L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12837
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.215
ARL2BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67186
mRNA_NANOG_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
intermediate part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02923
amino acid:monoatomic cation symporter activity	GO Molecular Function Annotations 2025	1.0	null
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Tay-Sachs disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.107
outer CP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17575
CABLES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9927
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12723
abnormality of carboxylic acid metabolism	HPO Gene-Disease Associations	1.0	null
PU.1	MotifMap Predicted Transcription Factor Targets	1.0	null
vacuolar part	GO Cellular Component Annotations 2015	1.0	null
IZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05544
DB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39934
SCRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25042
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BD-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54471
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.886763
MIF4GD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29219
glycine-gated chloride channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.552
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.910986
GSE220520_5_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adipocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.066
inorganic ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062166
VAL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47316
A band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.236
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44266
Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44204
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MY-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85758
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Endocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03285
CORT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18292
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93901
GSE68155_1_v_0_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-371b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
HMGB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59602
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AMIGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07751
TMEM9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28271
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
ARSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90967
skeletal system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852807
GSE178255_3_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903027
INMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27823
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57663
mantle zone of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09867
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60062
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.06691
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
IL17RC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60218
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
brownfat	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36925
CDK5RAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89486
DDX56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33027
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.885803
AMBRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73803
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2168
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09563
MLLT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09952
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPS4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60627
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045957
ITM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1914
NR3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94227
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
COQ5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51814
Ebolavirus(ZEBOV)_1day_Liver_None_GSE57214	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.09164
MTFP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46966
Hyperglycinuria	ClinVar Gene-Phenotype Associations 2025	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spinocerebellar ataxia type 34	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
Ventral nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.844
ACIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91029
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0331
vesicle	GO Cellular Component Annotations 2015	1.0	null
PSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77599
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UBE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39395
TLNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28686
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
KG1C	CCLE Cell Line Gene CNV Profiles	1.0	1.53651
WTAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.51871
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.9515
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051836
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057585
ST14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47052
AQR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37238
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.780336
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7045-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5402-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_pos_targets-Gene_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
NEK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43562
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34558
UTP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96201
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20136
HOOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67357
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	2.01892
ZSCAN16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15186
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172247,GSE172250_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130396_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
L-amino acid transport	GO Biological Process Annotations 2025	1.0	null
ZNF362	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46028
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03176
CACHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84661
inorganic cation transmembrane transport	GO Biological Process Annotations 2025	1.0	null
IRF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.17794
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.923021
TARBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77044
ZNF408	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36166
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18575
GTF3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27904
U87MG	Achilles Cell Line Gene Essentiality Profiles	1.0	1.01481
hsa-miR-3622a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.862608
organic anion transport	GO Biological Process Annotations 2015	1.0	null
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3334
POLI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35047
PU.1-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_791_KD_Irf3_SRP074478	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PPM1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10205
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-1826-SM-2XCE2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20923
Entorhinal area, medial part, dorsal zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07669
gefitinib_homo sapiens_gpl570_gse20854	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.900828
PLEKHA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12145
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43086
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDK2AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48942
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210476_11_v_7_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4187
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LK-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
apical part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.313344
Nephrotic syndrome type 21	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF3_02_54	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.73697
RTCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01286
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8Q9-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
hsa-miR-27a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EHBP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71285
r7 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62676
SOX2-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Persistent severe asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.037
subcallosal cingulate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25227
496100506_PCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.3766
GCNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01919
TM7SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75011
KG1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21048
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4768
MOLM16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38694
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.844
Perturb_7129_OE_Ppp3cc_SRP321708	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
r4 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2001
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-TML8-1626-SM-32QOO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25635
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
MNAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75254
TSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02604
hsa-miR-4433	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Retinitis pigmentosa 68	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
Perturb_1687_KO_Kmt2c_SRP283007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.43668
SF295	Achilles Cell Line Gene Essentiality Profiles	1.0	1.02497
DNMT3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5498
A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_2day-MOI-10^4_None_GSE37572	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.6595
OTUD7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8295
CRACR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02303
hsa-miR-23b	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
GLOD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03445
hypersensitivity reaction type ii disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.06839
Hip joint	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.768
sciatic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.305001
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0408
VDR-24787735-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE196699_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.28766
Hypodermal seam cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.076
GSE203308_4_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LPIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49587
PGC-1alpha_Deficiency_GDS4904_310_mouse_Aged gastrocnemius muscle - 10 weeks	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
L-alanine transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09674
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-S32W-2526-SM-2XCB8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933626
CHGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34995
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
r7 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38758
LEAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60427
lytic vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.21646
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cycloserine	DrugBank Drug Targets	1.0	null
C1orf35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.277
DG-75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02043
Rocky Mountain spotted fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.9
IER5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0834
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.971395
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
UBXN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41911
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872661
FOSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.72191
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
A-CA-04-2009(H1N1)MA_Day3_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.89872
INA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.901
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51296
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28806
Inflammatory bowel disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.45229
GSE246195,GSE246305_4_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RB1CC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86846
TMEM126A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91048
paclitaxel_homo sapiens_gpl570_gse19136	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC10810548-pone.0289518.s002.xlsx-SOM_w_identifiers-target_gene_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of the upper urinary tract	HPO Gene-Disease Associations	1.0	null
INAFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7735
GTPBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39327
NME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73313
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
EHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87654
biological_process	GO Biological Process Annotations 2015	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050738
hsa-miR-593	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PSAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70945
NB13	DepMap CRISPR Gene Dependency	1.0	2.22031
GSE134316_1_v_0_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FLT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12507
neutral amino acid transport	GO Biological Process Annotations 2023	1.0	null
GCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2362
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35581
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28325
Endoplasmic reticulum	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
NCIH1437	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.07252
L-proline transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28549
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE228162_2_v_5_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
COX5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47355
autosomal dominant inheritance	HPO Gene-Disease Associations	1.0	null
SULF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89262
horsetail-astral microtubule array	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.559
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MIDEAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33774
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.2425
EOLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09615
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5862
hsa-miR-2278	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CMAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97774
LYL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FOSL1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GCT	CCLE Cell Line Gene CNV Profiles	1.0	1.60826
ARFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23625
renal	GAD High Level Gene-Disease Associations	1.0	0.293278
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
ASPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10596
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ABHD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92412
GSE216538_0_v_3_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KYSE-270	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23222
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24448
at1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.869
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38548
thyroiditis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.463527
Brain Lower Grade Glioma_LGG_TCGA-DU-8163-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03802
GSE169617_1_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GON4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76766
WWC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24497
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03405
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86667
GHITM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49951
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
TRIM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38454
SW 982	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22196
HCC56	DepMap CRISPR Gene Dependency	1.0	3.07773
excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49707
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38408
ARID3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95479
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10638
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.988908
PRDM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5303
extracellular organelle	GO Cellular Component Annotations 2015	1.0	null
Pollen tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.135
r4 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04201
FTC-133	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal renal morphology	HPO Gene-Disease Associations	1.0	null
ZNF521	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81436
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060615
RHOBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72479
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Invertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.124
PMC9643473-Table1.xls-MAF_0_005-HGVS_gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
ACCMESO1	CCLE Cell Line Gene CNV Profiles	1.0	1.67096
Gastrointestinal stromal tumor_Gastric Tissue_GSE15966	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.53229
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982009
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.20859
GSE216147_2_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
B3GALT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22986
dorsal lateral geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40342
ICC8	DepMap CRISPR Gene Dependency	1.0	2.25875
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67403
ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095613
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QXCU-0126-SM-2TC5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831751
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I0-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30626
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061483
Field CA3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66847
neurodevelopmental abnormality	HPO Gene-Disease Associations	1.0	null
LRRC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03151
skeletal muscle	HPA Tissue Gene Expression Profiles	1.0	1.32283
BLZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5888
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.325
Lung adenocarcinoma_LUAD_TCGA-93-A4JQ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPK-1726-SM-48TC4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958815
Endosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE149903_6_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00302
Dentate gyrus, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3503
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
Transmembrane transport of small molecules	Reactome Pathways 2014	1.0	null
myelinating schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.967657
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40431
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.907773
Perturb_15582_KO_Ctnnb1_SRP251042	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.05918
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.50022
BTRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44794
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17635
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF683	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13062
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZC3H7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48895
CCDC92B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50248
METTL7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33216
nitrogen compound transport	GO Biological Process Annotations 2025	1.0	null
MRPL47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5837
DDX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09039
NAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22726
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22558
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.880029
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
precuneus, right, inferior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.901663
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917984
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838882
Lung adenocarcinoma_LUAD_TCGA-44-3398-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13574
SMCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92235
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11508
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930467
HPCAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01646
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.86427
KHDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41985
MLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30642
C3orf18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45239
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dentate gyrus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2929
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54357
GTEX-Q2AH-1826-SM-2S1Q2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27765
GATOR2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.832
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.198
DHCR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31981
GTEX-T8EM-1526-SM-3DB7I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19474
PTP4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26814
MTERF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33149
Perturb_3223_KO_Nhe1_SRP366933	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.38928
Claw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.708
Perturb_788_KD_Foxk2_SRP145105	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.471
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37672
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44229
Perturb_7125_KO_Prkce_SRP049245	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.78378
TMEFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5636
C15orf62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87071
Perturb_1109_KO_Nkx2_SRP032537	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-9.18024
GLUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77879
SMRT-22465074-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PPP1R14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61701
hsa-miR-3689c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
SNU410	CCLE Cell Line Gene CNV Profiles	1.0	2.30752
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2613
PHLDA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23446
GSE239578_5_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pedunculo(pontine) tegmental  nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36557
LY6E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92796
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47207
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053062
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FN-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.863
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46658
Tentacle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
GSE88819_7_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23798
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4511
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
CD164L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04168
STS-0421	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intermediate stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11183
foot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.499615
endosome membrane	GO Cellular Component Annotations 2023	1.0	null
GOSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05725
ion transport	GO Biological Process Annotations 2015	1.0	null
ATF3_02_180	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.45943
monoatomic ion transport	GO Biological Process Annotations 2025	1.0	null
PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-Proximal_Tubule_Enriched_Genes_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Proton-coupled neutral amino acid transporters	Reactome Pathways 2024	1.0	null
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058704
RKN	Achilles Cell Line Gene Essentiality Profiles	1.0	1.32061
ZNF491	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11643
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.59802
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DM-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-organism transport	GO Biological Process Annotations 2015	1.0	null
DiaA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.756
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02189
SNU840	DepMap CRISPR Gene Dependency	1.0	2.42075
GTEX-QDT8-0526-SM-3NMD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15223
RUNX1_KO_GDS1511_250_mouse_Embryos at E8.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
doxycycline_homo sapiens_gpl570_gse21912	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormality of glutamine family amino acid metabolism	HPO Gene-Disease Associations	1.0	null
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.51222
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PIGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25234
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A8O6-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916426
GTEX-T2YK-0326-SM-4DM7D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33453
vacuolar membrane	GO Cellular Component Annotations 2015	1.0	null
VCY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52806
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
B9D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03284
Brill-Zinsser disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.508
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.877439
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3923
H3K27me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD2-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
H3K27me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC2A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.97691
RPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75851
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30453
GTEX-WRHK-1626-SM-3MJFH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868645
l-alanine transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
TAF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37804
YWHAE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.38468
hsa-miR-3689a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE255432_7_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Tuber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.16
TRIP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76107
PYGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37236
MAPRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46468
SARS-CoV MA15_Day2_None_GSE49262	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.55383
layer 2 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05718
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92081
ANP32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80614
IPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82304
RAB11FIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97782
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055661
Leydig cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.988
EVX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94143
hsa-miR-424	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
ZNF606	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19304
Integral component of postsynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.588
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.1604
BAIAP2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68041
FOXM1-26456572-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.848
establishment of localization	GO Biological Process Annotations 2015	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.842404
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.863003
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE220520_1_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PIAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46308
ZNF212	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75776
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03724
FOXA1-25552417-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6667-01A-12R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
celiac disease	GAD Gene-Disease Associations	1.0	null
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939801
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32006
C1RL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5375
MMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56132
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.29684
hsa-miR-1271	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
LRIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77619
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE111102,GSE111105_4_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ventral posteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12213
Hyperplasia	CTD Gene-Disease Associations	1.0	1.20361
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.883447
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.76512
PCOLCE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50002
GSE130396_0_v_2_braf_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166169_1_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.946109
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
all	HPO Gene-Disease Associations	1.0	null
CDON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
ATP-binding cassette (ABC) transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.642
ELOVL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91424
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
KMT2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96052
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050706
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.997973
RPS27L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86557
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.917644
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0458
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.66957
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6222-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PROSER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61285
vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07111
Hypodermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.287
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3863
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ERF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42486
PRELID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11171
Perturb_9488_KD_Appbp2_SRP359770	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.1406
GSE105406_0_v_3_ptcd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DDX28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77944
POLR3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62097
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
Childhood spinal muscular atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0495
leg	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.155906
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	1.0	2.09745
GSE196699_4_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C1orf159	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58835
EKVX	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20588
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05451
inorganic cation transmembrane transport	GO Biological Process Annotations 2023	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4EO-0126-SM-3P5YN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18097
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.62869
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17127
L-proline transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
PEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56951
SHROOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36348
HSD17B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56283
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05744
EEF1AKMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30515
CD151	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07706
carboxylic acid transport	GO Biological Process Annotations 2025	1.0	null
intermediate stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2466
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MDAMB157	CCLE Cell Line Gene CNV Profiles	1.0	2.42207
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20039
SEMA4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.22196
GTEX-VUSG-2626-SM-4KKZI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965536
OE21	DepMap CRISPR Gene Dependency	1.0	2.05182
FEZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91097
PLPPR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02208
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13733
GSE149124,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PSAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25865
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30253
TRMT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49529
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43667
ASH3	DepMap CRISPR Gene Dependency	1.0	2.37876
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
COG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95034
EVA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85231
Integral component of endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.223
CCNYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61697
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A1CF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82003
Integral component of postsynaptic density membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.794
GSE184902_3_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-X88G-0326-SM-47JZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6061
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61602
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20501
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.96514
estradiol_homo sapiens_gpl96_gse4668	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Chronic obstructive pulmonary disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.863
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.00027
ae2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.624
disease	GWASdb SNP-Disease Associations	1.0	0.02751
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61127
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QLQ7-1826-SM-2S1R5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993444
MYCBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46674
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998146
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70316
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hippocampal formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22471
ZNF513	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59128
Biceps femoris	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.953
PPP1R13L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44994
FGF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45021
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39311
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.572
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGA2_KO_GSE55340_21_mouse_lung (E18.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
methotrexate_homo sapiens_gpl571_gse9412	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
MG-63	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inner SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10219
ATP6V1F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56232
ATRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02826
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.78264
ALKBH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10453
STAT3-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54159
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
autoimmune thyroiditis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.480945
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A5RJ-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vacuolar membrane	GO Cellular Component Annotations 2025	1.0	null
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
FLVCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8669
KDM5B	ENCODE Transcription Factor Targets	1.0	null
psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.198709
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.825395
GSE178255_5_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IFT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90672
hsa-miR-4284	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6024
GTEX-POYW-0426-SM-2XCEV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918539
496100535_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.12604
prolinuria	HPO Gene-Disease Associations	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.399492
abnormal autopod morphology	IMPC Knockout Mouse Phenotypes	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5696-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05968
periventricular stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11521
Rennet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.945
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38271
PMC9643473-Table1.xls-MAF_0_005-Gene_refGeneWithVer_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Failure, Chronic	HuGE Navigator Gene-Phenotype Associations	1.0	null
MFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96321
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25728
TMEM143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01567
hsa-miR-3160-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
HCC1395	DepMap CRISPR Gene Dependency	1.0	3.39813
TRIM39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60757
GSE149123,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
VWA5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81596
hsa-miR-3919	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
ULK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75557
Renal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
kidney	HPA Tissue Protein Expression Profiles	1.0	0.808111
CCDC163	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28846
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.00399
prostate	HPA Tissue Gene Expression Profiles	1.0	0.832763
BRD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55349
KLF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62201
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22188
Gonadal sheath cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.431
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1275
PMC12179525-mmc1.xlsx-Group_HNF4A_vs_Null_sign-Supplemental_Table_S1_Differentially_expressed_genes_in_HNF4A-transduced_cells_vs_Null_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
CAL-72	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22648
RAD21-21589869-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kco	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
GSE189772,GSE189773_3_v_2_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
iminoglycinuria, digenic	OMIM Gene-Disease Associations	1.0	null
Perturb_17775_OE_Tgfb1_SRP325964	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.72557
SRF_KO_GDS3732_148_mouse_HSC	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
kidney	HPA Tissue Gene Expression Profiles	1.0	1.68543
YY1-21170310-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE138019_1_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
t70-white-adipose_male_2w	MoTrPAC Rat Endurance Exercise Training	1.0	1.78557
RPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82686
PRSS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28828
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8237
Ornithine translocase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.553
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A0C8-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOB3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75314
Lysosomal lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.641
Glume	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.989
Mat-Ly-Lu cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
cell part	GO Cellular Component Annotations 2015	1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2838
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
GSE179974_3_v_4_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.50555
GSE214596,GSE214598_1_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.61682
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GALNT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01449
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13754
TCEAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58548
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
SMAD4	ChEA Transcription Factor Targets	1.0	null
HDH_CAG knock-in_GDS3935_569_mouse_Striatum and cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GB1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.11223
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4935
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961138
D283MED	DepMap CRISPR Gene Dependency	1.0	2.13329
MLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41677
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00379
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43359
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053777
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09238
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054631
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.66889
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	1.88402
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00946
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0918
GMPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01986
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.249
PPIH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89792
kidney disease	GWASdb SNP-Disease Associations	1.0	1.39396
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35581
mantle zone of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38758
GTEX-RU72-1126-SM-2TF6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13876
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830155
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25694
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52041
hsa-miR-4435	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Intrinsic component of postsynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.557
mode of inheritance	HPO Gene-Disease Associations	1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24918
superficial stratum of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39937
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042219
GTEX-WRHU-0826-SM-3MJFN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44264
P4HTM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40196
decitabine_homo sapiens_gpl571_gse29077	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.994404
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE156907,GSE160237_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-154	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6695
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27647
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22196
RFX5_02_61	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.87447
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
NCI-H2452	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15122
GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82219
Brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.211
GTEX-WYBS-0326-SM-3NM8S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12862
BICR31	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5982
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
urinary system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5615
PALM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15885
BNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78836
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PAT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.881
PLCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27922
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4269
496100530_FWM_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.52499
DQX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37902
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.893584
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17441
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20819
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.3296
ZNF804B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01525
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16916
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NOL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50559
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1918
EZH2	ENCODE Transcription Factor Targets	1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0779
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055089
FUS-26573619-CHIP-SEQ-HEK293-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE119978,GSE180930_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.872561
RBM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43605
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.917644
SLC7A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15065
NCIH196	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.24167
Field CA3, stratum lucidum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85026
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C2CD4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27302
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939801
BABAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96271
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26168
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-5096	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82015
organic cation transport	GO Biological Process Annotations 2025	1.0	null
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF217	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66657
ZNF141	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08942
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.981797
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_18392_KO_923large_SRP286259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.5278
PNMA6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48356
hsa-miR-940	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
SDHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91076
intracellular part	GO Cellular Component Annotations 2015	1.0	null
RBCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01482
SEC23IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47641
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3705
SMAD3-21741376-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
amygdaloid complex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07361
GTEX-SNMC-1626-SM-4DM52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33791
PU-27001747-CHIP-SEQ-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
M band	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.308
col7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.99
ZNF33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19421
oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.824013
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.933447
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-153	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05058
Vacuolar membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Olivocerebellar fiber system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
Primary visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35404
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149903_6_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A816-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
HSPB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33015
NCIH82	DepMap CRISPR Gene Dependency	1.0	3.07409
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3547
Hartnup disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
Perturb_4659_OE_Mir18a_SRP322958	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.1029
abnormality of urine homeostasis	HPO Gene-Disease Associations	1.0	null
Amino acid transporter, transmembrane	InterPro Predicted Protein Domain Annotations	1.0	null
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053154
Shelterin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.893
GSE158431_5_v_1_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SUCS-1726-SM-32PM8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981608
Trachea	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.6756
OR2B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85325
central lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0171
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7915
muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Iminoglycinuria	ClinVar Gene-Phenotype Associations 2025	1.0	null
inner SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00039
GSE172020_1_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH1963	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35755
LN-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.123347
Nephrotic syndrome type 22	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.104
PROSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86572
Lung adenocarcinoma_LUAD_TCGA-05-4422-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R3RS-0526-SM-3GADG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6163
GSE218907_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173873_4_v_6_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PTGIS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84222
intermediate stratum of DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42694
HdhQ111/111_Knock-in_GDS4534_744_mouse_Striatum and cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046551
LRRC55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76515
UPCISCC029A	DepMap CRISPR Gene Dependency	1.0	2.08397
FZD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60268
GSE96991,GSE97117_5_v_2_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE113106_0_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bacteriocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.555
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13835
vitamin c_homo sapiens_gpl570_gse11919	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF704	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09562
UGGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99951
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.932408
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62258
LRATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90857
Periplasmic side of cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.532
VEZF1_02_179	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.48543
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.661523
DAGLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70395
ALAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41751
496100369_PCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11634
hsa-miR-1827	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ZBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73171
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
toxin-antitoxin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.01
H3K27me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8329-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYNM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51342
CKAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06772
Astigmatism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
stomach	HPA Tissue Protein Expression Profiles	1.0	1.79385
GTEX-PWCY-2126-SM-48TEC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864231
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31752
RCOR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84112
TAF2-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
pm85	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.15
r3 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17862
GTEX-NPJ7-1726-SM-2YUNA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08492
SMARCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40559
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31686
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6068
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE81193_3_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
F8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9238
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.630485
SMIM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24732
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3171
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ABHD17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77244
ZNF595	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98876
ISHIKAWAHERAKLIO02ER	DepMap CRISPR Gene Dependency	1.0	4.18314
TOR1AIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25874
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61192
H3K27me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A172	Achilles Cell Line Gene Essentiality Profiles	1.0	1.72378
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.913
l-amino acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Perturb_4354_KD_ERK3_SRP238353	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PSN1	Achilles Cell Line Gene Essentiality Profiles	1.0	2.70384
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.7734
Anteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.199
Field CA3, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14618
ZNF662	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54819
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.09506
DPY30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28789
SLC44A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27022
QGP1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.68261
TCF4_01_185	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59155
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146074_0_v_11_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.715
NISCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53228
NAP1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13119
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
PBDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7422
SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.881972
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02043
Perturb_12745_KO_Cd274_SRP080936	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.81703
IDH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12572
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.45482
FHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83137
HIRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66282
HMGB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11614
Kidney renal clear cell carcinoma_KIRC_TCGA-6D-AA2E-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.857148
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4787
Dorsal fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.14
OPM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36364
PROSER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15998
AHCY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97664
MCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54429
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88826
Hyperekplexia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40971
Dorsal part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30924
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.839694
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PCDHB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30381
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.881265
GTEX-PWN1-1726-SM-2S1O9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848106
GSE179031_3_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.175411
SSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31017
Spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60749
Acrocallosal syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
Otosalpingitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.152
SNX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49139
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.51222
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PANC0327	DepMap CRISPR Gene Dependency	1.0	2.85725
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SH3BGRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54596
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.29853
CHD1_02_187	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.90689
intermediate stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.158
PUF60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20379
SMAD2/3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MAP3K6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56062
NR4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98694
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
OPM2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.36468
GTEX-XYKS-2526-SM-4BOPX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0728
Perturb_7040_KO_Srsf5_SRP309981	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.31366
Conceptus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.367
hsa-miR-323-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20166
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59937
RXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92334
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.946
DCLRE1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82504
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68276
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Biceps	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.736
extracellular vesicle	GO Cellular Component Annotations 2015	1.0	null
IFT25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16903
GSE228894_3_v_2_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Phagolysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.056
SAP130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74503
ETV1_01_161	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.63001
DAPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13008
amino acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
HT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4755-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62208
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37513
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	72.9264
Activating signal cointegrator 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.546
aminoaciduria	HPO Gene-Disease Associations	1.0	null
STAT6_02_57	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.16993
alanine transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07907
Pollen wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.647
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me1_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ABHD17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4919
EMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87587
hsa-miR-4486	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
JAR cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
UCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10632
ZNF195	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61667
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30392
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13134
ANKLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81368
CTBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33791
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6649
OGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80339
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.90128
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01997
SIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0592
HOXA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57349
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.856411
layer 3 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1059
Hydranencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.180367
periventricular stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24038
SP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77759
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.336
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59483
MAFG_02_189	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.69188
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43552
Perturb_7054_KO_Tead1_SRP229838	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.19619
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09563
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
Perturb_8069_KD_SFPQ_SRP281189	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.72215
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cormel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.199
CEBPB-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CAVIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84269
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35401
PMC9950457-mmc3.xlsx-GRHL2_overexpression_UP-gene_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
HNRNPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54526
SCMH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12993
transporter activity	GO Molecular Function Annotations 2015	1.0	null
NDUFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20536
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80696
5-hydroxy-L-tryptophan	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
IGR1	DepMap CRISPR Gene Dependency	1.0	2.34448
GSE88819_6_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MIX23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66186
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARHGEF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87788
GSE226091,GSE226092_3_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050858
KLF7_KO_GDS2069_68_mouse_olfactory epithelia	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.7557
NPIPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75638
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
superficial stratum of CA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59577
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HT144SKINFV1	DepMap CRISPR Gene Dependency	1.0	12.9922
Perturb_16630_KO_Plxnd1_SRP385920	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.04223
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
TCF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74304
SMAD4-21741376-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SEMA4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23244
Recycling endosome membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
NRSN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07431
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30431
endoplasmic reticulum membrane	GO Cellular Component Annotations 2025	1.0	null
aciduria	HPO Gene-Disease Associations	1.0	null
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.845591
TANGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00308
PU.1-20513432-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897326
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.9619
TSC22D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69558
Nexine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.835
GSE88819_0_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01037
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.877864
SOX10_KO_GDS3480_257_rat_Schwannoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Obstructive lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.863
KMS12BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46495
NCOA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48074
Abdominal adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.218
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11939
S100A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95286
GTEX-SSA3-0326-SM-32QPS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80727
ATP1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26008
Plastid thylakoid lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.918
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11855
DDRGK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.471
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860408
GSE88819_0_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZBTB7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06517
hydrogen transport	GO Biological Process Annotations 2015	1.0	null
SMAD2	ChEA Transcription Factor Targets	1.0	null
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898541
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0112
SLC66A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92467
Matrix fibroblast_Lung_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
HDAC3_KO_GDS4886_29_mouse_heart - 6 week old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Microbody membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.975
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28611
Brain Lower Grade Glioma_LGG_TCGA-HT-7858-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08784
RCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.93103
cingulate gyrus, retrosplenial part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36693
MT-ND4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28111
r3 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24786
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DYNLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11351
SKMM2	DepMap CRISPR Gene Dependency	1.0	2.20838
Perturb_787_KD_Irf3_SRP074478	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.8019
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30265
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10194
umbilicalcord	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.974429
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.908623
PRR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44314
H3K4ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
INO80B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74285
APEH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26914
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mRNA_ZFAND3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
NRARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5292
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21394
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
SNRNP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41306
496100356_TCx_probable Alzheimer's disease_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02294
cellular process	GO Biological Process Annotations 2015	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100402_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16197
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
cation transport	GO Biological Process Annotations 2015	1.0	null
IQGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39681
SLC38A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58192
estradiol_homo sapiens_gpl570_gse23610	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-578	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.857063
FUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66544
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SLC39A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42142
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.830442
GSE114258_1_v_0_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-96	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044333
Distal tip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.135
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Preadipocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.051
HCST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16578
hsa-miR-4795-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Endemic typhus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.868
PTMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34581
DOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54633
STOML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67499
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GP2D	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.38881
RUNX3	ENCODE Transcription Factor Targets	1.0	null
TEAD4_02_40	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.11548
MAP2K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52013
Type V protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.209
LRRC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56517
NIPAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86076
3t3-l1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.281423
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
SAMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48154
NDUFA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16033
PNKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59046
hsa-miR-3926	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.432
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.99942
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.927026
GSE233256_0_v_1_rbms1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
urinary tract	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Inferior colliculus, central nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24347
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.032512
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PD-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_7072_OE_hMYL2_SRP182648	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
MRPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08904
Iminoglycinuria	DisGeNET Gene-Disease Associations	1.0	null
GSE165308_1_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Synaptic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.3
Human - Kidney - L2 - Proximal Tubule Epithelial Segment 1	HuBMAP Azimuth Cell Type Annotations	1.0	null
OCIAML2	Achilles Cell Line Gene Essentiality Profiles	1.0	1.1389
REPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09478
abnormality of metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
subcallosal cingulate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.93153
KIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46488
HOXB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90726
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21764
neutral L-amino acid transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CLEC11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86553
r5 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07344
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178255_3_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CAPZB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50344
hydrogen ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
dorsal cortical nucleus of inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86197
PMC10290283-biol-2022-0622-sm3.pdf-349-TFE3_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
thiamine-responsive megaloblastic anemia syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
Field CA2, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90375
hsa-miR-518a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.107229
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07502
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
EIF2AK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07272
GTEX-UPJH-0626-SM-4IHJN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955975
NCI-H2023	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.879048
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03891
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vincristine_homo sapiens_gpl570_gse7556	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-328	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3136
Posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11005
primary motor cortex (area M1, area 4)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0472
SAC3D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55826
NHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53444
UCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29716
PMC12216174-41598_2025_6356_MOESM13_ESM.xlsx-Sheet1-Supplementary_Table_3_Classification_of_amino_acid_AA_transporters_at_four_different_subcellular_localizations_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
HTC-C3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47747
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956938
Type IV secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.78
GPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49058
GTEX-QESD-1726-SM-2S1R7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08843
GTEX-QLQW-1426-SM-2S1QU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907812
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831813
TP53INP2_OE_GDS5053_312_mouse_Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TXNL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34297
hsa-miR-769-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28917
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10754
Type VI protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.995
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.842404
mature ovarian follicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.104344
t60-adrenal_male_1w	MoTrPAC Rat Endurance Exercise Training	1.0	2.31939
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.876419
hilus of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42628
organic acid transport	GO Biological Process Annotations 2015	1.0	null
GSE216538_0_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Intrinsic component of cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.532
estradiol_homo sapiens_gpl570_gse5102	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
layer 1 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30441
SLC25A39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15243
CRTAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10523
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10754
Lung adenocarcinoma_LUAD_TCGA-73-4676-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8048-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145445,GSE145454_0_v_1_cop1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPSA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76554
cation transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5K0-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chloroplast thylakoid lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.936
Gangliosidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08656
Rhinencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.045
Perturb_11901_KO_Irf8_SRP265303	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.280717
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.895654
r4 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11349
GSE143499_0_v_1_gata6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.205
alanine transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0194
White adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.919
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46595
SMARCA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01711
NCIH1648	CCLE Cell Line Gene CNV Profiles	1.0	1.65673
GTEX-R55F-0226-SM-48FCI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25807
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34347
Field CA1, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4531
SH3D19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35436
GTEX-PLZ5-1626-SM-3NB21	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842687
TOB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3018
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MED10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49974
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH1836	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42654
TULP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69858
GSE179974_3_v_2_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_1_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
GFI1B	ChEA Transcription Factor Targets	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18975
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Boutonneuse fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.94
HOXC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99566
CDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53441
HMGB1P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3059
CENPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45888
ZNF280A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5061
H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Type II spiral ganglion neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283545
Lymphnode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.79931
GTEX-X638-0426-SM-47JY2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.584
TUBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64204
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-X4XX-0626-SM-3NMC1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52945
Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDC25C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19913
amino acid transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60236
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43468
microbody	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-QDT8-0326-SM-32PL1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848491
ATOH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43052
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50125
MAP1LC3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64058
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spotted fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.93
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28308
bounding membrane of organelle	GO Cellular Component Annotations 2023	1.0	null
GNG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17558
GTEX-XQ8I-0726-SM-4BOPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26475
FXYD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27057
Chloronema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.886
TBX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80314
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.207709
solute:proton symporter activity	GO Molecular Function Annotations 2023	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864767
GTEX-Q2AH-1926-SM-2S1PN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8455
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5691-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99369
H4C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85171
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TMMY-0526-SM-33HBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09045
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09227
carboxylic acid transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.874638
cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Amino acid transport across the plasma membrane	Reactome Pathways 2014	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
ZNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98484
carboxylic acid transport	GO Biological Process Annotations 2015	1.0	null
carboxylic acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Transport of inorganic cations/anions and amino acids/oligopeptides	Reactome Pathways 2014	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
ZSCAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60759
periventricular stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17624
adipose-derived stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.071
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1572
CORL51	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56571
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.81049
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52604
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0142
DCTPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2365
calcium nephrolithiasis	HPO Gene-Disease Associations	1.0	null
tretinoin_homo sapiens_gpl96_gse5007	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_789_KD_Foxk2_SRP145105	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.00208
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058717
GSE239578_2_v_3_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179031_3_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_pos_targets-ID_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
MAVER1	DepMap CRISPR Gene Dependency	1.0	4.52325
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23778
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20588
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5948
HOXD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82436
Field CA1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50929
GRK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36244
RCBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33828
Treacher Collins syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
ERFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42186
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83751
EPCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40051
Acute disseminated encephalomyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
MFSD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10154
hsa-miR-527	TargetScan Predicted Conserved microRNA Targets	1.0	0.107229
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02436
ZNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43888
Perihypoglossal nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70682
GTEX-XBED-2526-SM-47JYD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935605
GSE180200,GSE180201_3_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Seh1-associated complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.695
CNPY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19823
Tonsil	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.25725
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.87323
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	1.0	1.34806
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50945
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5988-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
cation:amino acid symporter activity	GO Molecular Function Annotations 2015	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A44G-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CPNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46492
CPXCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95052
Field CA1, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55354
KLLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70632
ACAD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3749
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
Spastic tetraplegia, thin corpus callosum, and progressive microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.592
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTPBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6003
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_18394_KO_Ivl_SRP286259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.03166
Field CA2, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.29685
ARHGAP45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27902
HCC515	DepMap CRISPR Gene Dependency	1.0	2.14753
DGKQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57589
GSE88819_6_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hereditary spastic paraplegia 42	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902742
Field CA2, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60486
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28917
Iminoglycinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.033
hsa-miR-23a	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
Perturb_1429_KO_Prkcd_SRP386893	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
ENTREP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67309
ENSG00000284691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30719
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56779
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998146
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10815
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	5.09791
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.325
CNMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02791
NAP1L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5976
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial pallium (hippocampal allocortex)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28062
symporter activity	GO Molecular Function Annotations 2015	1.0	null
Inferior colliculus, dorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22249
SETDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51794
hsa-miR-4786-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Amino acid transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.985
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965891
lateral group of nuclei, left, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01868
GTEX-XPT6-2126-SM-4B66P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16386
Myelinating Schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.133
Bam protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.532
active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-1268	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
FNDC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22615
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC25A52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9781
Iminoglycinuria	CTD Gene-Disease Associations	1.0	2.88009
LMBR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28878
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4321
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40215
SLC12A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6073
PMC8755441-mmc3.xlsx-IRF1-UP-Symbol_IRF1	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.0453
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dense body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.425
PRRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73578
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48032
NFKB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03179
corpus luteum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.355942
hydrogen:amino acid symporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924556
GSE235234_2_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE245134_0_v_1_atg5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10038
vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.172735
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
GATOR1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.774
BRD4-27068464-CHIP-SEQ-AML-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
r6 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09867
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	5.6137
SYS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51936
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79315
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
Vacuole	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Perturb_7093_OE_Ppp3cc_SRP310497	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.5698
proline:proton symporter activity	GO Molecular Function Annotations 2025	1.0	null
proline transmembrane transport	GO Biological Process Annotations 2015	1.0	null
SH3BP5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08912
DMS153	CCLE Cell Line Gene CNV Profiles	-1.0	-2.23797
ZIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44636
TAT protein transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.063
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10260405-41588_2023_1409_MOESM6_ESM.xlsx-ST12-Supplementary_Table_12_Most_likely_causal_genes_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946349
Intrinsic component of postsynaptic specialization membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.687
SARM_KO_GDS4842_411_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3886
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.366381
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.624
RHBDL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96756
SLC25A28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36692
HCC1171	CCLE Cell Line Gene CNV Profiles	1.0	1.66386
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76328
GSE179974_3_v_5_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PAPOLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59217
GSE81193_0_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZCRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03706
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.22373
IL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21692
GORASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58064
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.93474
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.616
Chromosome 19q13.11 deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39572
PIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75782
CRX-20693478-ADULT_RETINA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84409
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056581
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Body Mass Index	dbGAP Gene-Trait Associations	1.0	0.248184
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03891
metabolic	GAD High Level Gene-Disease Associations	1.0	0.293278
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_6228_KO_Mbnl1/Mbnl2_SRP142522	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.38274
icSARA deltaORF6_30Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.47798
abnormality of amino acid metabolism	HPO Gene-Disease Associations	1.0	null
PKN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66674
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69185
RUNX1	ChEA Transcription Factor Targets	1.0	null
TAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04603
GSE145215_0_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RMI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2905
Medial cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.798
GSE138872,GSE138874_0_v_1_il33_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
hsa-miR-4448	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3EV-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Field CA3, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61394
SRC_activemutant_51_GSE15815	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.56781
H3K27me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14426
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.85089
DCAF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02689
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79209
GFI1B-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZG-0326-SM-47JXN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0745
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.47322
hsa-miR-4289	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hypersensitivity reaction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058242
GTEX-SSA3-0526-SM-32QPL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21255
hyperglycinuria	HPO Gene-Disease Associations	1.0	null
L-amino acid transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
TRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9685
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050469
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7402
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE205316,GSE205317_2_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6919
RIPPLY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06532
Perturb_2149_KO_Piezo1_SRP226320	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.39706
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74691
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37964
MOR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.880029
KHDRBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41066
MRPL38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43855
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SPRING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79308
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11199
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06443
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34749
ARFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61006
l-proline transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE178255_1_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S95S-1526-SM-2XCDH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04851
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03575
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ventral posteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19219
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55251
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051739
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.316224
GSE111102,GSE111105_2_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE68147_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-0326-SM-2TF6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08162
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Intermediate spinal muscular atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
CELF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35214
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.4515
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73553
SNU620	DepMap CRISPR Gene Dependency	1.0	2.61443
LCMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99876
Digenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.833
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14591
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29304
ALDOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53639
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Myosin filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.028
HOXC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38131
LN-229	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Juvenile spinal muscular atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.404
anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.91266
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86544
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.834454
GTEX-WL46-0426-SM-3TW8J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916518
DDX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45373
Very long chain acyl-CoA dehydrogenase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
GTEX-OHPN-2726-SM-2I5H4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.11076
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
intermediate stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01103
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.30259
SREBF2	JASPAR Predicted Transcription Factor Targets	1.0	null
Primary cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.625
IQCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87015
GTEX-XXEK-2526-SM-4BRUR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04845
TP53INP2_OE_GDS5054_276_mouse_SKM-Tg - Skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE114690_1_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NB7	DepMap CRISPR Gene Dependency	1.0	2.21342
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10545
SW1088	CCLE Cell Line Gene CNV Profiles	1.0	1.34358
ZNF587	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0891
GTEX-NPJ8-1726-SM-2YUNB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04373
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF385A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74204
abnormality of proline metabolism	HPO Gene-Disease Associations	1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916426
Nodulus (X)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80448
METTL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78578
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39311
r6 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17505
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
Palpus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
HCT116	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.30351
precuneus, right, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14009
HYPERGLYCINURIA	CTD Gene-Disease Associations	1.0	2.88009
Parasubiculum, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11897
embryonic fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083289
GSE157594_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE255432_7_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5353
Cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00522
FLI1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MCCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69236
Proximal tubule transport	WikiPathways Pathways 2024	1.0	null
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50121
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10965
GSE113106_2_v_1_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
L-alanine transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
H2AC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43353
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AP-3 adaptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.038
EYA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99955
PLPPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79447
proline transport	GO Biological Process Annotations 2015	1.0	null
inner CP in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.947727
GATA2	ChEA Transcription Factor Targets	1.0	null
GEMIN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43431
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.00424
METTL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93219
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GFI1B-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27013
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51938
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.320956
Queensland tick typhus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.913
GSE208254_4_v_1_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC38A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34169
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SNAPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16118
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
organic acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64039
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
α-methyl-D L-tryptophan	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
IFT57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11949
SLC30A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43313
EXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08678
PMC9666480-Table_4.xlsx-P73_Class_I-Unnamed_1_TP73	Rummagene Transcription Factor Associations 2026	1.0	null
NTMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97162
TCF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14601
SHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.235
abnormality of serine family amino acid metabolism	HPO Gene-Disease Associations	1.0	null
hsa-miR-2392	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Glycinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.84
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ARID3A	JASPAR Predicted Transcription Factor Targets	1.0	null
ZNF398	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13524
PARP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25395
hsa-miR-4792	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35373
SEMA4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29305
HES3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64922
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.3865
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051107
hsa-miR-23c	TargetScan Predicted Conserved microRNA Targets	1.0	0.111118
GTEX-P4QT-1726-SM-2S1NQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918465
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05396
single-organism process	GO Biological Process Annotations 2015	1.0	null
orbital frontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.934842
Adult spinal muscular atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.542
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55617
STN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66008
mantle zone of CA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59495
Brain Lower Grade Glioma_LGG_TCGA-DU-5870-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04247
PMC3245917-supp_gkr685_nar-01129-x-2011-File015.xls-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
H4K20me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CCDC152	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61193
WDR5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63597
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	212.924
Hyperekplexia 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWS6-2426-SM-2XCB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05748
ADAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69398
Ventral anterior-lateral complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0721
GTEX-T6MO-2026-SM-33HB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13863
RMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.586
ALG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44918
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.0189
SCAMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84098
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
kidney	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
VERO-76 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.646
hsa-miR-508-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
FAM124B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49374
Vacuolar lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.798
OCUG1	DepMap CRISPR Gene Dependency	1.0	6.6808
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.26578
inferolateral temporal cortex (area TEv, area 20)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0772
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39575
Cervicovaginal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24654
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872338
GSE255432_6_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.133314
PMC7305081-10120_2020_1045_MOESM1_ESM.xlsx-Tab2-Mutation-MAF_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0198
IGLON5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44853
anion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4106
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
c16	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AR-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25099
GSE216147_0_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r7 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04044
GTEX-OXRK-0426-SM-3NB2E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08357
GTEX-QCQG-2026-SM-2S1PH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963345
extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CHD7	ENCODE Transcription Factor Targets	1.0	null
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01047
HCC44	DepMap CRISPR Gene Dependency	1.0	3.98145
SF539	DepMap CRISPR Gene Dependency	1.0	2.02781
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83298
schwann cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.317679
Adrenocortical carcinoma_ACC_TCGA-OR-A5JL-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Defective SLC36A2 causes iminoglycinuria (IG) and hyperglycinuria (HG)	Reactome Pathways 2024	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6107
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.987354
ZNF774	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72773
INSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63333
TIMM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44181
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50274
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z5-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180200,GSE180201_15_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_9485_KD_Appbp2_SRP359770	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.8947
Japanese spotted fever	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.261
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950876
Perturb_14436_OE_Cyp17_SRP340317	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.53929
METAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69114
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18226
PRODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3307
glycine transport	GO Biological Process Annotations 2023	1.0	null
hsa-miR-1285	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14418
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HAND1_cust_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TSE9-0526-SM-3DB7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964157
Mesocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
CXCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44312
hsa-miR-4752	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Abnormality Of The Eye	DisGeNET Gene-Phenotype Associations	1.0	null
GSE220813_0_v_1_zfp750_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S3XE-1926-SM-3K2B3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92455
MARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21281
Spadix	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.793
CEP170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04892
3T3-L1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.186
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15122
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.99395
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A197-06A-32R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.920897
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00907
hsa-miR-3613-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
hsa-miR-4495	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Cytoplasmic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8348
lat1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.78
Polygenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.76
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.77556
H3K27ac_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-CI-6624-01C-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29128
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1216
SMAD3	ChEA Transcription Factor Targets	1.0	null
Integral component of postsynaptic specialization membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.718
MTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72943
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.842404
MINDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37701
GSE184884_6_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6030-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
subgenual (subcallosal) division of MFC (area 25)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0422
paranode region of axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.901818
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31812
EGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18371
OVCAR8	Achilles Cell Line Gene Essentiality Profiles	1.0	1.58319
Mitochondrial DNA depletion syndrome 7	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
RAB6D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27261
ATOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20235
TM9SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34906
CR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64031
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.096121
Prostate adenocarcinoma_PRAD_TCGA-VN-A88K-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93669
ERMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04578
GSE111385_0_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218580_1_v_4_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FCHSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23948
TIAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21924
Skin aging (microtopography measurement)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
Amino acid and oligopeptide SLC transporters	Reactome Pathways 2014	1.0	null
AGAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77478
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04103
SND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65202
alanine transport	GO Biological Process Annotations 2015	1.0	null
SWI5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3412
Hip	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.833
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15408
Disease	Reactome Pathways 2024	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZU-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-27b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43468
OCIMY5	DepMap CRISPR Gene Dependency	1.0	5.80108
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.928229
carboxylic acid transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
single-organism localization	GO Biological Process Annotations 2015	1.0	null
hsa-miR-612	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE152055_0_v_1_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Posterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02414
PMC12706077-44318_2025_598_MOESM21_ESM.xlsx-Dataset_EV19-hKidney_TPP-PISA-Genes_ZNF568	Rummagene Transcription Factor Associations 2026	1.0	null
GSE251992_1_v_0_saracatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56852
MCF10DCIS.COM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902742
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0013
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27675
GSE89767_6_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adipocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.913
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3637
SZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.854223
molecular layer of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4134
IOMMLEE	Achilles Cell Line Gene Essentiality Profiles	1.0	1.29205
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.68556
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.676664
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39551
mantle zone of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02769
MALME3M	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76859
hsa-miR-483-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8002-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12569
GTEX-X4EP-0726-SM-3P5YJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05245
Field CA1, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13907
GTEX-WOFL-0626-SM-3MJG3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04735
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80736
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.815699
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.895741
CRX-20693478-ADULT-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KIAA1549	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35893
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NACA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78296
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.86093
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3259
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
COMMD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05983
Costamere	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.139
Dentate gyrus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24637
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Hmgn1_KO_GDS5010_406_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CLDN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20488
TNPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71068
GTEX-XUJ4-2726-SM-4BOQ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02425
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
Cell envelope Sec protein transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.596
ARHGEF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05506
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040318
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.855273
muscle	GTEx Tissue Gene Expression Profiles	1.0	1.27979
cellular_component	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-3622b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Perturb_6985_OE_Ppp3cc_SRP321708	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PTPN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35264
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YV-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65557
LAPTM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57302
ZNF814	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30862
CTNNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45041
GSE185944_5_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MDFIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45583
PABPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93199
Fat pad	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.892
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
superficial stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04201
KIAA0232	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90482
CHERP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.34711
PMC3470785-NIHMS377161-supplement-3.pdf-548-POU6F1_POU6F1	Rummagene Transcription Factor Associations 2026	1.0	null
CLSTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15211
TLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06062
Postsynaptic density membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.521
solute:proton symporter activity	GO Molecular Function Annotations 2015	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3-20064451-CD4+T-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042162
MRPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12958
NME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09511
Lung adenocarcinoma_LUAD_TCGA-97-A4M2-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MM160113	DepMap CRISPR Gene Dependency	1.0	9.35633
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Strabismus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
Sarcosine	HMDB Metabolites of Enzymes	1.0	null
ATP2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12278
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.99765
Integral component of organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.168
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.02341
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
CPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6794
Lung adenocarcinoma_LUAD_TCGA-44-3918-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06471
GSE81193_3_v_4_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
superficial stratum of DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41206
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.224645
EXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17868
MESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75089
Posterior parietal association areas, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16662
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13909
ZNF613	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6479
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JD-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34314
METAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06775
GSE81193_0_v_4_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amino acid transport	GO Biological Process Annotations 2015	1.0	null
MTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81866
Perturb_1818_KO_Adam17_SRP394864	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.8665
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
5-HYDROXYTRYPTOPHAN	DGIdb Drug Targets 2026	1.0	4.411
TIGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17857
peroxisome	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77403
SG in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.956506
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.920741
ARMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19684
organelle part	GO Cellular Component Annotations 2015	1.0	null
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28549
all	GWASdb SNP-Phenotype Associations	1.0	0.030334
ZNF648	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90654
ATP1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25545
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.8554
PMC5097440-12864_2016_3198_MOESM4_ESM.xlsx-Adipose_ind-INDEPENDENT_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
recycling endosome membrane	GO Cellular Component Annotations 2023	1.0	null
vascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071402
Lung adenocarcinoma_LUAD_TCGA-MP-A4TK-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DPPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78154
GSE242167_1_v_2_cd40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ASH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58569
l-amino acid transport	GO Biological Process Annotations 2015	1.0	null
ICC3	DepMap CRISPR Gene Dependency	1.0	7.88417
ACSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84781
COL9A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57669
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.230409
GTEX-POYW-0526-SM-2XCEY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12436
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
Field CA3, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75736
E2F4	ENCODE Transcription Factor Targets	1.0	null
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AP1B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62321
Endoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Israeli tick typhus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
H2BC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77795
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
GTEX-WRHU-0626-SM-3MJFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36585
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1086
FHIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29821
COL6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34942
FLII	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41768
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.2647
PMC12216174-41598_2025_6356_MOESM13_ESM.xlsx-Sheet2-Supplementary_Table_3_Classification_of_amino_acid_AA_transporters_at_four_different_subcellular_localizations_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GDPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.66328
PPM1K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10884
pretectal region	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27561
SMAD3-21741376-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
ZNF605	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18337
SLC37A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82539
GSE149903_5_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
olfactory tubercle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10523
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06471
MBLAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02101
GSE180200,GSE180201_2_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amino acid transport	GO Biological Process Annotations 2025	1.0	null
LTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91972
SUCLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02603
GSE114258_1_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49689
RERF-LC-SQ1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IFFO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65541
NCIH1105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94414
lateral part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19177
CDK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07411
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2687-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32747
ZNF575	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29915
ZNF724	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67497
COLO-792	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hippocampal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50929
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.843037
SHISAL2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57048
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.848481
KNS-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
micropexophagy-specific membrane apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.047
superior periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55402
Extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01021
ECC10	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07318
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.880029
NCIH211	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62131
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CAV1_Deficiency_GDS3551_559_mouse_Hearts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.061152
Caulonema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
CAMKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75574
SH3YL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26355
toe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.867686
HERC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5783
E2F4_02_200	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.62803
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0282
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-h-Classification_of_camel_SON_basal_genes_-_transporters_SON	Rummagene Transcription Factor Associations 2026	1.0	null
KDM4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7052
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03415
PMC11976269-41375_2025_2519_MOESM3_ESM.xlsx-ChIP_GATA2_Cluster_A-GeneName_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0367
CAL51	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.287
UXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36213
PLIN5_OE_GSE44192_482_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRUNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44915
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
ZNF395	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79258
Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPTC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9477
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.64464
GSE88819_11_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF620	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93679
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.871852
DNAJB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62685
DCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90521
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.132954
recycling endosome	GO Cellular Component Annotations 2025	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37738
VCX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50396
cisplatin_homo sapiens_gpl570_gse15372	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.08136
VANGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48183
COLO668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50097
Lateral dorsal nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06388
hydrogen ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00434
posterior (ventral) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16933
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endosome membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nephrolithiasis	HPO Gene-Disease Associations	1.0	null
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0053
aorta endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.501182
Perturb_17757_KD_Esrra/Esrrg_SRP217321	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04015
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.614
Renal tubular transport disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.947
Macronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.845
JPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26684
SMAD4-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01618
SCARB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99134
FXYD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90273
proton transport	GO Biological Process Annotations 2015	1.0	null
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
TM-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.997
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amino acid transport	GO Biological Process Annotations 2023	1.0	null
peripheral neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.482084
H1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1114
SIRPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79693
SMAD3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PIWIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84481
CLPSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61877
Preadipocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.682
GTEX-OXRO-1726-SM-3LK6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872402
SMAD3-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07507
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49178
17975224-TableS6	GeneSigDB Published Gene Signatures	1.0	null
ROMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06257
inorganic cation transmembrane transport	GO Biological Process Annotations 2015	1.0	null
GSE149903_0_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDK5RAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88943
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80736
TNFAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02898
RUNX2	ChEA Transcription Factor Targets	1.0	null
r8 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03429
TUBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55371
CACNG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50749
GTEX-WHWD-2326-SM-3LK6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907298
Pontocerebellar fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
ZNF675	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60519
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IKZF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64067
ATP-independent citrate lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.828
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879133
PMC9643473-Table1.xls-MAF_0_005-Gene_refGenecanonical_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.21646
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39871
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LIN54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47384
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887019
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.47767
hsa-miR-346	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
TP53INP2_OE_GDS5054_545_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Foveal hypoplasia 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A85H-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SS18L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6361
GTEX-RNOR-0326-SM-2TF51	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951523
amino acid:proton symporter activity	GO Molecular Function Annotations 2023	1.0	null
ZNF615	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03883
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60261
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.906904
ZNF461	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42581
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Agranular insular area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06131
NB1	DepMap CRISPR Gene Dependency	1.0	2.61977
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7376
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21011
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.479
secondary active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78444
Body wall muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.263
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
embryoday6.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.85578
Gyrate atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40699
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13107
REST	ENCODE Transcription Factor Targets	1.0	null
SMAD2-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RPS6KA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.254
CCNDBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42455
creb1_22108299_heart_left_ventricle_lof_mouse_gpl1261_gds3660	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.09581
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09987
CH25H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24383
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
HIPK1_knockout_170_GSE39253	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.828974
calcium oxalate nephrolithiasis	HPO Gene-Disease Associations	1.0	null
NSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19707
LATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4429
ZNF180_02_177	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.63743
Organelle subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05543
Prostate adenocarcinoma_PRAD_TCGA-J4-8200-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149903_0_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_7053_KO_Tead1_SRP229838	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
localization	GO Biological Process Annotations 2015	1.0	null
ABAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96371
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27034
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904061
MZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.83504
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZH-1626-SM-3DB74	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35368
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MPHOSPH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23419
ACOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52265
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE216538_1_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-XOTO-0326-SM-4B66K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30244
BACH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7509
alanine transport	GO Biological Process Annotations 2025	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-A46L-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3614-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.107229
Superior olivary complex, periolivary region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24532
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.978827
HIPK2_knockout_171_GSE39253	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.5861
RPS6KA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96038
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.979652
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.41822
Endomysium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
ZBED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24224
SELENOV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8657
C17orf49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23116
H1-10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14438
SHISA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.16347
hsa-miR-4311	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PMC10123531-NIHMS1874945-supplement-Table_S3.xlsx-SOX17_BCAT_cobound_coreg_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.944652
GSE107854_2_v_0_prmt5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0287
496100502_TCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.12604
EPLC-272H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PSDG-0426-SM-2S1OF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973453
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05925
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEL4-0426-SM-3GACZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947196
COL4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11009
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7286
GSE184892_0_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178255_5_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Transport of small molecules	Reactome Pathways 2024	1.0	null
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43012
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MMAC-SF	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.92734
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_2198_KO_Map3k7_SRP237503	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.40366
extracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-R55G-2126-SM-2TC67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843214
XPNPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79944
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15065
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4465
IGSF9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97917
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.880029
PRR5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8664
IFNLR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61181
RALY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41812
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051895
FAM216A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95011
Hyperglycinuria (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
SELENOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33247
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930266
carboxylic acid transport	GO Biological Process Annotations 2023	1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.115
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.69026
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70404
Ammon's horn	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64376
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Longissimus thoracis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.877
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.168
hsa-miR-556-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Intracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
LHX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50468
IFT122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81043
LRRC8D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45412
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56757
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00155
Adams apple	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
Yolk granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.71
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.030376
REXO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70702
SRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69066
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934142
Heterocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.997
spinal trigeminal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.894649
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
LARP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85863
CCDC160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30343
CD68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95111
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02043
H2AB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14457
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07744
DU-4475	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Stomodeum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.831
bounding membrane of organelle	GO Cellular Component Annotations 2025	1.0	null
Proton-coupled neutral amino acid transporters	Reactome Pathways 2014	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.863
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14782
GSE111102,GSE111105_3_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AKT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86097
Blepharochalasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
Brain Lower Grade Glioma_LGG_TCGA-HT-7884-01B-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3185	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
EIF4E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94369
amino acid:proton symporter activity	GO Molecular Function Annotations 2025	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.844693
posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.960738
recycling endosome	GO Cellular Component Annotations 2023	1.0	null
Vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.83467
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16492
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MU-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4425-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESPNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42107
GTEX-SNOS-1626-SM-3NMA4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909717
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.203604
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM131B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41596
SSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92718
hsa-miR-187	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Perturb_18400_KO_Wnk1_SRP247391	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.05324
Fatty acid elongase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.69
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	1.21853
subgranular zone of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29304
r8 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11521
abnormality of the kidney	HPO Gene-Disease Associations	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
UBL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37903
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.064454
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54154
GSE114272_0_v_1_clk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89922
SOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67865
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68188
Amino acid transport defects IEMs 	WikiPathways Pathways 2024	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.917556
Subcutis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.549
Lung adenocarcinoma_LUAD_TCGA-38-4625-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20234
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.940791
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.807
NRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38062
Human - Kidney - L3 - Proximal Tubule Epithelial Segment 1	HuBMAP Azimuth Cell Type Annotations	1.0	null
NPAS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48831
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79938
superficial stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30626
A427	DepMap CRISPR Gene Dependency	1.0	3.74251
B4GAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67524
AXIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64663
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060983
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
non-suppurative otitis media	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.649
THAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54927
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.45066
496100381_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06793
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040558
Nodulus (X), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.97967
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
layer 1 of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05873
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
FOSL1::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.089
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.989025
aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093737
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PPM1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89321
FLI1	ChEA Transcription Factor Targets	1.0	null
GSE111102,GSE111105_1_v_5_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80842
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Field CA1, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5263
ESRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62265
DSG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98829
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Uterine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.931
basomedial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45217
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
paclitaxel_homo sapiens_gpl570_gse11550	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
INSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50388
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4321
MDAMB415	CCLE Cell Line Gene CNV Profiles	1.0	1.50073
CMBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41909
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NGRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85669
CORL88	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36689
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16975
alanine transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
MAPK15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6444
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73028
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
abnormal autopod morphology	MGI Mouse Phenotype Associations 2023	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LN443	Achilles Cell Line Gene Essentiality Profiles	1.0	1.00159
CASKIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29922
monoatomic cation transmembrane transport	GO Biological Process Annotations 2025	1.0	null
GSE114992,GSE114993_8_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16191
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
renal proximal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.56005
Prostate adenocarcinoma_PRAD_TCGA-HC-7821-01A-12R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
glycine transport	GO Biological Process Annotations 2025	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peripeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14225
KAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90626
IFT20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53266
MTARC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92453
GMPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85234
endosome membrane	GO Cellular Component Annotations 2025	1.0	null
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41157
GCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92297
gemcitabine_homo sapiens_gpl96_gse6914	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
C7orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61877
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4342
NSMAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70665
FASTKD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64273
Excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PRKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27098
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21625
Perturb_16093_OE_Jun_ERP104759	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.5302
hsa-miR-4425	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
GSE100316_7_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13324
KNS60	DepMap CRISPR Gene Dependency	1.0	2.34417
endoplasmic reticulum membrane	GO Cellular Component Annotations 2023	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
NRDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15456
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964266
16166618-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
ACAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93467
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Telomerase catalytic core complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.66
KMS34	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53179
Sarcoma_SARC_TCGA-K1-A6RT-01A-32R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12909843-41467_2026_68388_MOESM4_ESM.xlsx-fig3g-up-regulated_gene_expression_in_OTX2-KO_8CLCs_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Supportive connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.583
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.886796
RSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24679
KMRC2	CCLE Cell Line Gene CNV Profiles	1.0	1.63878
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.879048
Spikelet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.91577
Rectal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
monoatomic cation transmembrane transport	GO Biological Process Annotations 2023	1.0	null
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11399
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34723
RAD21_02_190	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	5.24793
GSE196699_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
proton transmembrane transport	GO Biological Process Annotations 2023	1.0	null
decitabine_homo sapiens_gpl570_gse30985	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ARID3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11085
trigeminal	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
WTIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56599
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nih-3t3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.185424
esophagus	HPA Tissue Gene Expression Profiles	1.0	0.890972
CARD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63588
HMGA2_KO_GDS5048_26_mouse_embryonic lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE180200,GSE180201_2_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
l-alanine transport	GO Biological Process Annotations 2015	1.0	null
a11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
hsa-miR-4717-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PMC9578714-elife-81083-supp2.xlsx-AA_Transporters-Common_Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WY7C-2626-SM-3NB2P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967142
monoatomic ion transport	GO Biological Process Annotations 2023	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48061
Symbiosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.139
GSE111102,GSE111105_3_v_5_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
principal sensory nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.852004
SMAD4-21741376-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE127970_1_v_3_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900959
Peripheral blood stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
PGC-1alpha_Deficiency_GDS4904_311_mouse_Aged gastrocnemius muscle - 24 months	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.82988
hippocampus (cortex Ammonis)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59577
ARPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60528
DPRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58998
Dicarboxylic aminoaciduria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.699
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53363
Perturb_6991_KO_Trx1_SRP190456	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE184902_3_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046691
proline:proton symporter activity	GO Molecular Function Annotations 2023	1.0	null
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2017
SMAD3-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
RHOD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78096
496100476_TCx_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04177
GTEX-S341-1926-SM-3K2BA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26243
STAT3	ChEA Transcription Factor Targets	1.0	null
hsa-miR-3614-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.03694
NDST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05848
GTEX-V955-2526-SM-4JBJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07282
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.2185
LSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39569
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9578714-elife-81083-supp2.xlsx-AA_Transporters-Ensembl_ID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
ENGASE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51586
Primary somatosensory area, trunk, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30318
HSP90AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51053
GTPBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57506
GTEX-XUW1-0626-SM-4BOP4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966458
SLR21	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.18207
GSE96991,GSE97117_5_v_0_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16768
ARPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47449
GATA2-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.874858
SH2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55
nitrogen compound transport	GO Biological Process Annotations 2023	1.0	null
OXSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83604
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831767
SET2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05406
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.23582
RNF166	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10858
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.67631
GSE220520_6_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.065573
Perturb_14520_KO_Gata6_SRP023469	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.37692
Lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
GSE113005_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
alanine transport	GO Biological Process Annotations 2023	1.0	null
nerve	GTEx Tissue Gene Expression Profiles	1.0	0.986413
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40882
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
METTL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23479
LYL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
WDR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59784
PMC9618568-41467_2022_34255_MOESM4_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
KPNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42233
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3182_KO_Actn2_SRP218915	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0572
r3 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19713
PMC9578714-elife-81083-supp2.xlsx-AA_Transporters-Gene_Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.32028
CX3CL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00015
CASC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92679
GSE130217_5_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prolinuria	DisGeNET Gene-Disease Associations	1.0	null
Perturb_4306_KO_TET1/TET2/TET3_SRP251780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.5021
CIPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07454
GSE212299_3_v_0_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146074_6_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FABP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90457
transport	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TW-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29518
SOX9-26525672-CHIP-SEQ-LIMBBUDS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC9666480-Table_1.xlsx-P73-Unnamed_1_TP73	Rummagene Transcription Factor Associations 2026	1.0	null
SHISA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07408
STAT3	ENCODE Transcription Factor Targets	1.0	null
periventricular stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03943
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_9752_KO_Rnf20/Rnf40_SRP228497	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.45312
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20501
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31333
GTEX-U3ZH-1926-SM-4DXTR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19958
R3HDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74437
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56923
GSE96991,GSE97117_5_v_1_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
methionine-importing complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.913
RARA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
monovalent inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
CORL279	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48034
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3336
TNFRSF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28211
abnormality of glycine metabolism	HPO Gene-Disease Associations	1.0	null
hsa-miR-3922-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
abnormality of the urinary system physiology	HPO Gene-Disease Associations	1.0	null
p95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.915
Field CA2, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53978
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.42217
Amino acid transport across the plasma membrane	Reactome Pathways 2024	1.0	null
PLEKHB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48207
PES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30078
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06434
UST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8632
NCI-H1573	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41942
Human - Kidney - L1 - Proximal Tubule	HuBMAP Azimuth Cell Type Annotations	1.0	null
HIF1A_01_348	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.76158
Disorders of transmembrane transporters	Reactome Pathways 2024	1.0	null
CBX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55518
mantle zone of r4BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19059
Vertebral endplate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.75
Perturb_147_KD_Zfp407_SRP051775	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE198254_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053105
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0571
RBBP5	ENCODE Transcription Factor Targets	1.0	null
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04101
excretory gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
central nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16898
superficial stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09907
Field CA2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59413
STRADA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03237
adrenalgland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02933
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5734
increased aggression	IMPC Knockout Mouse Phenotypes	1.0	null
Celiac Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE137144_2_v_0_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterine anchor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.433
mantle zone of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03276
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30422
GSE185944_2_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.13011
A375SKINCJ3	DepMap CRISPR Gene Dependency	1.0	2.31097
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05128
Peroxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.976
YY1	ChEA Transcription Factor Targets	1.0	null
COLO741	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59495
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926124
MBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10692
CENPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29808
H3K27me3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
solute:cation symporter activity	GO Molecular Function Annotations 2015	1.0	null
RNASE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37727
hsa-miR-4636	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
P2RY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41545
PTPRZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58808
FOSL1	ENCODE Transcription Factor Targets	1.0	null
SLR25	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.15363
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
IVNS1ABP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77982
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
icSARS CoV_7Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.89938
U2SURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97599
COCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98995
H3K27me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06625
GTEX-WH7G-2626-SM-3NMBE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980353
496100522_PCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.02251
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.351485
VPS33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4349
Epidemic typhus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.144
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DNAJB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54798
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6255
neutral amino acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-OXRP-2526-SM-2S1NO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1028
NCIH2887	DepMap CRISPR Gene Dependency	1.0	4.63571
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
proline transmembrane transport	GO Biological Process Annotations 2025	1.0	null
Microspore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.783
RIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18347
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60869
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Intergeniculate leaflet of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00003
hsa-miR-3187-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Primitive endoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19772
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A267-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4684-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
Mosaic variegated aneuploidy syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.025
GATA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.082
IRAK4_Deficiency_GDS2641_653_mouse_Embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
body mass index	GAD Gene-Disease Associations	1.0	null
ZNF510	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71408
RAD21-21589869-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.20839
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.21327
dexamethasone_homo sapiens_gpl3921_gse28896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MSS51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72879
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38117
MGAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95382
GTEX-VUSG-2726-SM-4KKZJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938093
BMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77752
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5589-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C15orf39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00018
SEMA4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34241
STK17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24319
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55364
immune	GAD High Level Gene-Disease Associations	1.0	0.295739
Muscle tendon junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.074
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r5 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01151
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49H-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGPAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39445
TP53INP2_OE_GDS5054_387_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
GPANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34049
Superior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17624
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.83845
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21175
GTEX-OHPN-2926-SM-3LK65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951102
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7725-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Yolk	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.669
Nucleus of the solitary tract, gelatinous part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50362
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30751
TARS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38344
neutral amino acid transport	GO Biological Process Annotations 2025	1.0	null
CCNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56578
GTEX-R55E-0426-SM-2TC65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30865
METTL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64549
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RNF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07091
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intrinsic component of organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.286
extracellular vesicular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3257
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PNMA6F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66796
hsa-miR-632	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Female pudendum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.18
Protein digestion and absorption	KEGG Pathways 2026	1.0	null
BAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27732
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.23065
GTEX-POMQ-2026-SM-2S1OD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990376
WDFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72493
GSE113106_2_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE100316_7_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04891
DUSP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28092
Acute Myeloid Leukemia_LAML_TCGA-AB-2971-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SGPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22587
GSE178255_3_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6987-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PHLPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8616
ZNF879	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26692
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04779
DLG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88401
NUDT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46131
H3K27me3_iPS-20b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RWDD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37059
FOXH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04543
MEST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44312
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
amino acid:monoatomic cation symporter activity	GO Molecular Function Annotations 2023	1.0	null
HEG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90283
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Extracellular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
superficial stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03379
External female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.177
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OVCAR4	CCLE Cell Line Gene CNV Profiles	1.0	1.88402
MORC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34197
CORL311	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43408
RELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1988
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56852
ZNF677	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46827
KLHL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54109
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87272
MTFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5237
GSE100732,GSE100733_0_v_1_lrpprc_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC transporter disorders	Reactome Pathways 2024	1.0	null
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00889
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.863
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7478
LYL1	ChEA Transcription Factor Targets	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.830071
Intrinsic component of postsynaptic density membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.776
ARRDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.446
Colon - Sigmoid	GTEx Tissue Gene Expression Profiles 2023	1.0	4.3565
GTEX-WYJK-0326-SM-3NMA8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953421
DNAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17391