association dataset threshold value standardized value RXRA::VDR JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.6 LIPT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58598 Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PZ-01A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ACCMESO1 CCLE Cell Line Gene CNV Profiles 1.0 1.66599 Nfat5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.6798 CLPX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39461 dorsomedial tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04412 YAMATO DepMap CRISPR Gene Dependency 1.0 2.02754 Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SH-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleus of the diagonal band, left, horizontal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.07466 MZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04579 Subesophageal ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.819 ZNF432 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61925 TAGLN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64263 ZNF816 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.2555 SLC1A6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02413 GPS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62564 hsa-miR-4753-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Skeletal system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ETV7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.7622 IFIT5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8973 MAPKBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.37107 Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.7276 Lung adenocarcinoma_LUAD_TCGA-50-5935-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OBI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.80368 primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.839688 ZIM3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.9059 lateral (dentate) cerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19531 FOSL1::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.124 POLR2A ENCODE Transcription Factor Targets 1.0 null hsa-miR-4499 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 Scrotum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.649 Intrinsic component of endoplasmic reticulum membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.223 TSTD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59125 Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JL-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU1272 CCLE Cell Line Gene CNV Profiles 1.0 1.45036 hsa-miR-3613-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE155162,GSE155169_1_v_3_buparlisib_human RummaGEO Drug Perturbation Signatures -1.0 null ATF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43921 hsa-miR-509-3-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Ventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35401 Digenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.052 KCNK12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95026 MAGI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58319 FAM131A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47949 MOLM-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.8066 Ventromedial hypothalamic nucleus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09605 hydrogen ion transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null SYNGR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90164 Prostate adenocarcinoma_PRAD_TCGA-KK-A7B0-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46783 chr5_151259878_A_G_b38 GTEx eQTL 2025 1.0 1.14324 LOVO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06467 SDF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81457 GRHL3_01_336 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.62571 Neuropil TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.1 ARHGEF10L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9888 ZWINT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71003 MDA-MB-468 COSMIC Cell Line Gene Mutation Profiles 1.0 null sense organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053615 bounding membrane of organelle GO Cellular Component Annotations 2015 1.0 null NCIH2887 DepMap CRISPR Gene Dependency 1.0 2.77639 ZNF766 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0007 HEL COSMIC Cell Line Gene Mutation Profiles 1.0 null polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.26414 GSE111102,GSE111105_8_v_0_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null Invertebrate muscular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.029 ARL4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33912 FOXK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6591 hippocampus (hippocampal formation)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.975742 bounding membrane of organelle GO Cellular Component Annotations 2025 1.0 null MCF10DCIS.COM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.902613 TERB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19408 Heschl's gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00918 UTP18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32623 Cormel TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.4 Nfatc2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.7092 autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.043233 glycine transport GO Biological Process Annotations 2025 1.0 null GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.23461 Uterine Carcinosarcoma_UCS_TCGA-N8-A56S-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CCFSTTG1 DepMap CRISPR Gene Dependency 1.0 2.72202 TAL1-20887958-HPC-7-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE150688_2_v_0_ursolic acid_mouse RummaGEO Drug Perturbation Signatures 1.0 null r6 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2749 NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.4774 r3 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.87962 GSE119978,GSE180930_3_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null 496100315_TCx_no dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.10235 TTLL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63108 HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43438 PU-27001747-CHIP-SEQ-BMDM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Cranial nerve disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.032 C6orf120 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39932 SMURF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79293 SLC35E1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12272 NUB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7888 ZNF581 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80177 SFRP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52761 cellular process GO Biological Process Annotations 2015 1.0 null FAM241B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33715 respiratory system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053052 NCI-H1623 COSMIC Cell Line Gene Mutation Profiles 1.0 null SLC39A13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40268 NCI-H82 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.972682 SDE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8462 EMB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44225 Distal tip TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.613 GSE130081,GSE130082_5_v_1_neil2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Head capsule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.781 ZSCAN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21747 Pseudopodium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.957 MT-ND3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69415 DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.60064 PAX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1912 periventricular stratum of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41929 hydrogen transport GO Biological Process Annotations 2015 1.0 null AR ChEA Transcription Factor Targets 1.0 null THAP10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66462 alanine transmembrane transporter activity GO Molecular Function Annotations 2025 1.0 null hsa-miR-593 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_31_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null Crus 2, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58109 primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.77193 C6orf141 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80187 FOXP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0748 N4BP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60056 ZNF571 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.35478 Basal part of cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.822 VMRCRCZ CCLE Cell Line Gene CNV Profiles 1.0 1.33574 l-alanine transport GO Biological Process Annotations 2015 1.0 null TUHR14TKB CCLE Cell Line Gene CNV Profiles 1.0 2.09259 bed nucleus of stria terminalis, lateral amygdaloid division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21455 NACC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7458 NUDT14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33686 retina BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.837384 ABCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61281 hsa-miR-410 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.978743 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RN-01A-12R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mammillary area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37822 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z4-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZBTB18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.5203 SLC38A10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96081 hsa-miR-122 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 parvocellular part of the r9LRt Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06362 inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.94629 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IX, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.883096 preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.72439 S1P_Deficiency_GDS3654_521_mouse_Liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null RXRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 50.0473 PCDHB7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78783 primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.847639 primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.17101 periventricular stratum of r1BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14876 Palatine uvula TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.8 FGF21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23691 SLX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96502 EPHX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14487 CNBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10236 BICR16 DepMap CRISPR Gene Dependency 1.0 2.97838 smallintestine BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.4092 WDR54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3319 MAP3K21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64453 Parasubiculum, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08361 parastrial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07472 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17225 HNRNPLL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21709 vascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053087 PARP15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25395 UBA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95242 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31748 G361 CCLE Cell Line Gene CNV Profiles -1.0 -2.59447 Sarcoma_SARC_TCGA-DX-A7EO-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC35A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49488 HT-115 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.898 NCIH211 CCLE Cell Line Gene CNV Profiles -1.0 -1.42464 Bhlha15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.5239 UCHL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5147 CLASP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.58445 Brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.054 ZNF675 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.2118 H3K9me3_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null ATG4C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28079 primary auditory cortex (core)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.955394 Pharyngeal muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.577 Congenital myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.0 Lung adenocarcinoma_LUAD_TCGA-55-6971-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null supraoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.54625 A-CA-04-2009(H1N1)MA_Day3_22532695_GSE36328 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.08694 dorsal motor nucleus of the vagus (vagal nucleus) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06201 Mesothelioma_MESO_TCGA-MQ-A6BR-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cuneate nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.898732 TAF12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8879 ARID2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73508 SRCAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54436 CNIH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9102 EZH2_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF676 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38427 Prostate adenocarcinoma_PRAD_TCGA-EJ-5507-01A-01R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SEC14L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69977 SUMO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46197 primary auditory cortex (core)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.22938 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BM-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PYCARD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73455 Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA4_Deletion - for the second exon_GDS2316_712_mouse_Heart ventricles (of GATA4 animals heterozygous) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null paracentral lobule, anterior part, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.70461 NCI-H2023 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.854422 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MSANTD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83297 vacuolar membrane GO Cellular Component Annotations 2015 1.0 null TAPBPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50104 cardiomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.192657 PTGIS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84222 LBH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77006 SLC10A3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42918 ventral tuberomammillary nucleus, intermediate part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16036 primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.991113 H3K27me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE182185_0_v_1_pstk_human RummaGEO Gene Perturbation Signatures -1.0 null alanine transmembrane transporter activity GO Molecular Function Annotations 2023 1.0 null ESX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64955 inorganic ion transmembrane transport GO Biological Process Annotations 2015 1.0 null vacuole COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.085356 TUBB6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17893 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1X3-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Synaptic vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.502 PLPP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51489 USP12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.09168 MDAMB415 CCLE Cell Line Gene CNV Profiles 1.0 1.49175 RL952 CCLE Cell Line Gene CNV Profiles 1.0 1.38355 hsa-miR-548aa TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 periventricular stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75883 posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.30843 Pons BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.875591 cation transport GO Biological Process Annotations 2015 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2PG-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ascl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 52.4971 paraterminal gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.891034 Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV3-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A band COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.94 cingulate gyrus, parietal part, left, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.834839 mRNA_MYBL2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null NR2C2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69322 RC-K8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51899 laminin-10 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.658 NR4A2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7133 LUZP1-20508642-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_3914_KD_CTNNB1_DRP003300 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 2.79392 substrate-specific transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null COR-L88 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.80767 SOX17-20123909-XEN-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null hsa-miR-3188 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YV-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPP2R3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93935 primary motor cortex (area M1, area 4)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.946153 ion transmembrane transport GO Biological Process Annotations 2015 1.0 null TNFRSF12A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19199 PHOX2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02817 GSE161864,GSE161866_4_v_3_ror2_human RummaGEO Gene Perturbation Signatures -1.0 null stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.08303 olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30526 H3K9me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null LGMN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50079 Lung adenocarcinoma_LUAD_TCGA-55-6972-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Supramammillary nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20833 primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.40642 Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.863 ZNF92 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91346 hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10619 SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3556 lateral septal nucleus, intermedio-ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.2639 HCC1419 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.00662 MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.63578 GSE211226_1_v_2_sirpa_mouse RummaGEO Gene Perturbation Signatures -1.0 null SYDE2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02221 ERBB2_knockdown_234_GSE8373 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.67234 proton transport GO Biological Process Annotations 2015 1.0 null carboxylic acid transport GO Biological Process Annotations 2015 1.0 null KG1 CCLE Cell Line Gene CNV Profiles -1.0 -1.94452 inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08518 IRF3 ENCODE Transcription Factor Targets 1.0 null KDM5B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40401 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE100863,GSE100864_2_v_1_tet2_mouse RummaGEO Gene Perturbation Signatures -1.0 null hydrogen ion transmembrane transport GO Biological Process Annotations 2015 1.0 null GSE130081,GSE130082_0_v_1_neil2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Chronic obstructive pulmonary disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.863 primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.977724 Intine COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.64 GSE154767_1_v_5_adam10_mouse RummaGEO Gene Perturbation Signatures -1.0 null L-alanine transmembrane transporter activity GO Molecular Function Annotations 2025 1.0 null pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.44345 TRIM6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89866 HARA COSMIC Cell Line Gene Mutation Profiles 1.0 null H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K27me3_CH12.LX_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-AG-3902-01A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4418 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Testis TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 retromammillary area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33115 ATF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0774 ARMC7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67096 PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.842224 KLF4-25985364-ATHEROSCLEROSIS-LESION-MOUSE ChEA Transcription Factor Targets 2022 1.0 null hippocampus (hippocampal formation)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.17752 AR-21915096-LNCAP-1F5-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H1-4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71636 SYCP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50365 HMGCR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34028 SH2B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.82362 GDF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.86365 DNAJC2-21179169-NT2-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null carboxylic acid transmembrane transporter activity GO Molecular Function Annotations 2025 1.0 null posterior part of anterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34058 superficial stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7452 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HMGCS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81585 C9orf72 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85933 GSE156708_1_v_0_fbxo11_human RummaGEO Gene Perturbation Signatures -1.0 null PcPV part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04484 TMEM50A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14279 Mushroom body TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.464 Paraventricular hypothalamic nucleus, descending division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09866 REEP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93881 ECC10 CCLE Cell Line Gene CNV Profiles -1.0 -1.67068 pre-replicative complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.633 Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A5-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RNF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15428 ZNF337 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98863 hsa-miR-324-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 Mafg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.8241 RAD51B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82938 irf8_00000000_splenic_cd11bplusgrdash1_hdash2b_gen_background_lof_mouse_gpl6887_gse39228 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.654555 Proboscis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.082 gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.04883 Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.004 NCIH1105 CCLE Cell Line Gene CNV Profiles -1.0 -1.61358 GSE112860_5_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null FOSL1::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.7255 Nfatc1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.471 600MPE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.688728 hsa-miR-499-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 OVCAR4 CCLE Cell Line Gene CNV Profiles 1.0 1.88044 TRMT10A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72682 periventricular stratum of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07875 MDA-MB-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01421 hsa-miR-508-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.11662 Pollen coat COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.569 hsa-miR-935 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 Treacher Collins syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.061 gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14339 STK35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31411 primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.842934 hsa-miR-421 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 SUM159PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.694719 UQCC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77524 H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6982-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner CP in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.9917 FOSL2::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9477 PRELID3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11171 THAP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33347 hsa-miR-376b TargetScan Predicted Conserved microRNA Targets 1.0 0.303626 Brain Lower Grade Glioma_LGG_TCGA-TM-A7CA-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null glycine transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null KMS34 CCLE Cell Line Gene CNV Profiles -1.0 -1.36324 BCCIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.90296 inferior olive, medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.50508 RMDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.80291 EIF4A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65988 REL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46616 SLC66A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18322 laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00457 CORL51 CCLE Cell Line Gene CNV Profiles -1.0 -1.387 H zone COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.004 POMGNT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91306 SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.80447 monoatomic cation transmembrane transport GO Biological Process Annotations 2025 1.0 null CHST15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03008 carboxylic acid transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null SKBR3 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.62275 plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.425726 hsa-miR-4436b-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 PAT complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.909 VIIIA, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10654 subgranular zone of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08862 inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46338 DNAJC2-21179169-NT2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33781 Nerve cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.509 DNAL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.17391 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Hemidesmosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.933 H3K27ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 proline transport GO Biological Process Annotations 2015 1.0 null NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.855386 NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.634 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.836407 H2AC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98913 female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ZFP42 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.6136 VZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09136 mediodorsal nucleus of thalamus_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.38426 short insular gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.831912 GSE154464_1_v_3_cdk6_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_15031_Mut_Csf33_SRP347624 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 musculoskeletal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042819 FOXO6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9509 Hnf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.2714 periventricular stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.87348 Muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 METTL25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36561 H2BC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38932 L-alanine transport GO Biological Process Annotations 2023 1.0 null SMG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30763 PPOX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65057 PAFAH1B3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36333 GSE98964_0_v_2_tet2_mouse RummaGEO Gene Perturbation Signatures 1.0 null nitrogen compound transport GO Biological Process Annotations 2025 1.0 null l-amino acid transport GO Biological Process Annotations 2015 1.0 null SUM44PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.695941 MAT2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38198 SMARCD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35456 H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PCBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39696 submammillothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41592 Dorsomedial nucleus of the hypothalamus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09346 Paraflocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80398 CLMP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24788 NRP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03155 primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.33743 nitrogen compound transport GO Biological Process Annotations 2015 1.0 null SRD5A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02544 inferior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15093 orbital frontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.909999 male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BBLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85485 ESRRG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38277 cortex of cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4114 L-proline transmembrane transporter activity GO Molecular Function Annotations 2023 1.0 null skin GTEx Tissue Gene Expression Profiles 1.0 1.44862 neutral amino acid transport GO Biological Process Annotations 2023 1.0 null callosal sling Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.997878 I band COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.48 Basolateral plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.634 PTPRS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14639 KNS42 DepMap CRISPR Gene Dependency 1.0 2.01214 SU-DHL-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22187 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.411251 ZNF799 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87542 NCIH1581 CCLE Cell Line Gene CNV Profiles -1.0 -1.45222 Salivarygland BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.00757 primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.147 Prostate adenocarcinoma_PRAD_TCGA-EJ-8472-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amino acid:monoatomic cation symporter activity GO Molecular Function Annotations 2025 1.0 null superficial stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58444 VZ in midcingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06073 MKN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.917525 TUB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55289 ZNF586 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13583 MOR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.855386 l-proline transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null GSE197555_1_v_2_trametinib_human RummaGEO Drug Perturbation Signatures 1.0 null CGREF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92742 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10646 FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0071 Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.232 SOX17 ChEA Transcription Factor Targets 1.0 null Female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 paraventricular nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7394 BL41 CCLE Cell Line Gene CNV Profiles -1.0 -1.74808 Protocerebrum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.373 AP3M1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44075 Rectum adenocarcinoma_READ_TCGA-AF-2693-01A-02R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC22A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74698 PPARA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.38089 posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.836451 HOXB8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74055 Cortical amygdalar area, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06097 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8311-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intermediate periretromammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.88381 e3 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.561 RFX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3237 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.49806 central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.63678 NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.855386 Lung adenocarcinoma_LUAD_TCGA-44-6147-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mediodorsal nucleus of the thalamus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16742 HCC515 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.21616 RUNX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4988 tuber TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.993249 TMEM151A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26996 Tentacle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.743 PMC5105166-ncomms13331-s11.xlsx-Sheet1-Supplementary_Data_10_Overlap_of_upregulated_genes_in_MEF2D-rearranged_cases_with_public_ChIPseq_RNAseq_data_MEF2D Rummagene Transcription Factor Associations 2026 1.0 null MFSD10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.91428 cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.54375 CCSAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75212 TAF9B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71826 mantle zone of RMa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33167 VIIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.906002 Cortical amygdalar area, posterior part, lateral zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22326 MDAMB157 CCLE Cell Line Gene CNV Profiles 1.0 2.41811 Silique TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.882 MESD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75089 EXT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51586 UBR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47445 AN3-CA COSMIC Cell Line Gene Mutation Profiles 1.0 null proline transmembrane transport GO Biological Process Annotations 2015 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6VC-01A-23R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H2110 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KO-8407-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NB17 DepMap CRISPR Gene Dependency 1.0 7.98261 ARFIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23625 Rectum adenocarcinoma_READ_TCGA-EI-6507-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC7A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33923 THNSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32999 H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null estradiol_mus musculus_gpl4134_gse23072 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Glume TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.322 Perturb_16993_KO_Srsf1_SRP371030 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.37201 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01488 Labellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.512 Brain Lower Grade Glioma_LGG_TCGA-S9-A7J2-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null brain ventricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.108414 NDUFA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01001 Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SN-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC25A39 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15243 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1806 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.75152 ALAS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.01487 TR146 DepMap CRISPR Gene Dependency 1.0 2.64078 Prostate adenocarcinoma_PRAD_TCGA-KC-A7FA-01A-21R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAL-33 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.687 L-amino acid transmembrane transporter activity GO Molecular Function Annotations 2025 1.0 null UFSP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6208 Flocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.35047 X, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.84602 dorsomedial part of VMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47181 cardiovascular system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052606 SFSWAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43299 PMC9578714-elife-81083-supp2.xlsx-AA_Transporters-Ensembl_ID_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null POU3F1-26484290-ESCSS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null heart septal defect DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.648138 Very long chain acyl-CoA dehydrogenase deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.301 IZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19418 artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.062801 NR6A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.0128 III, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.19387 paravermis of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.33462 Spikelet TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.085 Superior colliculus, motor related, intermediate gray layer, sublayer c Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08458 Rennet TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.146 KIF3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57961 TM4SF18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13933 hsa-miR-4517 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 CEP68 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78549 EN COSMIC Cell Line Gene Mutation Profiles 1.0 null disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.181798 planum polare, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.27403 Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ABRACL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32966 RFXANK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37208 GSE155162,GSE155169_1_v_2_buparlisib_human RummaGEO Drug Perturbation Signatures -1.0 null TTC642 DepMap CRISPR Gene Dependency 1.0 3.45066 periventricular stratum of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18866 Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SLC4A7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05895 NCI-H2452 COSMIC Cell Line Gene Mutation Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XK-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RHOD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78096 Dopaminergic A13 group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05976 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7X0-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PPT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57542 Dorsomedial nucleus of the hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55405 TRIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48413 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-RA-A741-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NRM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86407 VSX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25278 Paraventricular hypothalamic nucleus, magnocellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40018 ZNF362 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46028 monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042679 PA1 DepMap CRISPR Gene Dependency 1.0 2.26114 OC314 CCLE Cell Line Gene CNV Profiles -1.0 -1.3617 mantle zone of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12335 GSE136742,GSE136744_0_v_3_setd2_mouse RummaGEO Gene Perturbation Signatures 1.0 null periventricular stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60519 SW837 CCLE Cell Line Gene CNV Profiles 1.0 1.541 Chromosome 19q13.11 deletion syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.335 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QR-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ADAMTS13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61723 TAL1 ChEA Transcription Factor Targets 1.0 null MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.916307 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null FZD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80795 NDUFB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58059 KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.854422 Lung adenocarcinoma_LUAD_TCGA-49-4487-01A-21R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null alanine transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null CROCC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85634 cerebralcortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.891051 hsa-miR-509-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 496100421_PCx_probable Alzheimer's disease_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.0802 r3 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14716 cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041324 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GU-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.147 ion transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRPS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05201 inorganic cation transmembrane transport GO Biological Process Annotations 2025 1.0 null Myosin filament COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.512 striatum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00982 TBX18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68199 LMO2-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null HT144 DepMap CRISPR Gene Dependency 1.0 4.83617 Crohn's disease GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.8699 CLIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64742 RNF185 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85169 Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null mammillary part of PHyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33064 Dorsomedial nucleus of the hypothalamus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.62348 AP5B1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32535 Entorhinal area, medial part, ventral zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10386 SW 982 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22187 MCCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69236 PITPNA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79533 SIX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48475 Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW 837 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28902 NR2F6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.479 NEMP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.52002 Lung adenocarcinoma_LUAD_TCGA-55-8091-01A-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null C18orf25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.91657 BET1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68098 H4K20me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-RY-A843-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor cortex (area M1, area 4)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0576 GSE110178_5_v_6_tranylcypromine_mouse RummaGEO Drug Perturbation Signatures 1.0 null Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.063 hsa-miR-1273g TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Hemidesmosome associated protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.111 BEX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36886 p4 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.737 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040369 COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27866 BT-474 COSMIC Cell Line Gene Mutation Profiles 1.0 null HAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40105 NCI-H2170 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1305 MCF 10A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3556 Strabismus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.089 BMAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6874 mantle zone of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02381 bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06448 SIN3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79896 SPI1-26923725-CHIP-SEQ-HPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MBD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59586 IZ in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.951051 RAB18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.84957 lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.39891 anterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.19154 fallopian tube GTEx Tissue Gene Expression Profiles -1.0 -0.960144 GDF9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6957 H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2913-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE159937_2_v_0_tfcp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-4529-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 MYF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9029 r5 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58444 primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.22152 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 r2 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.7595 IDH3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72695 Calyx TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.842 core part of DTg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12658 caudal ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.941396 Lung adenocarcinoma_LUAD_TCGA-55-6712-01A-11R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null g7 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.528 RUNX1-22412390-EML-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MYC-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Antennal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.005 IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37208 Gli2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.7191 TGBC11TKB COSMIC Cell Line Gene Mutation Profiles 1.0 null liver GTEx Tissue Gene Expression Profiles -1.0 -1.21003 Brain Lower Grade Glioma_LGG_TCGA-S9-A7IZ-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE211931_1_v_3_ncoa4_mouse RummaGEO Gene Perturbation Signatures 1.0 null anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.11403 EPN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20435 Sarcoma_SARC_TCGA-IS-A3K8-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HPS4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7377 yet GeneRIF Biological Term Annotations 1.0 null retina TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.069464 FUT10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74353 coronary artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.267977 TCF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1661 HMGB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.943 hsa-miR-499a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 Usher syndrome type 2C DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.084 LRRC73 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14328 GSE119978,GSE180930_2_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE112860_5_v_4_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null neuropathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.045649 monovalent inorganic cation transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null GSE157555,GSE157556_4_v_7_foxa2_mouse RummaGEO Gene Perturbation Signatures 1.0 null COLO741 CCLE Cell Line Gene CNV Profiles -1.0 -1.40712 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JP-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gonadal sheath cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.802 Lung adenocarcinoma_LUAD_TCGA-44-3398-01A-01R-1107-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DYNC1LI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8316 NCIH1573 DepMap CRISPR Gene Dependency 1.0 7.92284 DDX60L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02813 SBK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78336 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tay-Sachs disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.088 KCTD9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94864 NCI-H727 COSMIC Cell Line Gene Mutation Profiles 1.0 null intermediate stratum of THyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06156 KP-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18751 ECHDC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74593 supramammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.858119 inner SZ in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.28491 mRNA_SOX9_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U5-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intestinal GeneRIF Biological Term Annotations 1.0 null r7 part of cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02306 MIF4GD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29219 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7XN-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ALKBH4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09161 PRDM4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05036 Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.79584 COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.59435 SR-786 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11194 GNAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20104 NIPAL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86076 Flocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.23643 PAX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64186 C11orf96 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17346 GSE195559_6_v_5_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null NABP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51428 Central amygdalar nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22362 NCLN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22194 KBTBD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94541 HCC1319 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.81946 SHH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52199 WDR44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.66119 medial subdivision of central nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.82764 CHCHD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69447 SG in posterior frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.971901 ZNF205 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.08363 polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.909597 KMS-12-PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.22326 NB10 COSMIC Cell Line Gene Mutation Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H4-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null spleen BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.60594 CMK COSMIC Cell Line Gene Mutation Profiles 1.0 null HSBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85116 stratum radiatum of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0208 Brain Lower Grade Glioma_LGG_TCGA-DU-8163-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle part GO Cellular Component Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HW-8321-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ADAM8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14073 surface GeneRIF Biological Term Annotations 1.0 null DDX18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81994 Entorhinal area, medial part, ventral zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15042 Vacuole COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 DCAF17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51062 PLEKHG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45158 caudal interpeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1694 hsa-miR-3929 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 anion transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null U12-type spliceosomal complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.501 Sarcoma_SARC_TCGA-DX-A8BZ-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null subgenual (subcallosal) division of MFC (area 25) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.41846 CKB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29233 BRPF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44622 urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Body wall TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.694 Crus 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5608 periventricular stratum of JcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17292 D423MG DepMap CRISPR Gene Dependency 1.0 2.68358 MZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02021 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7862-01A-21R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPS15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4144 ZSCAN21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72328 CLK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.1645 cytoplasmic part LOCATE Predicted Protein Localization Annotations 1.0 null SCAP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5748 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.58947 Cortical amygdalar area, posterior part, lateral zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19849 SP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08796 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null Rectum adenocarcinoma_READ_TCGA-EI-7002-01A-11R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE159678_4_v_3_chloroquine_human RummaGEO Drug Perturbation Signatures -1.0 null RAB24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50917 Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7591-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SRY-25088423-EMBRYONIC GONADS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null MFE-319 COSMIC Cell Line Gene Mutation Profiles 1.0 null PHAX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26234 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null pallidal amygdala Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12372 Intrinsic component of organelle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.281 Erg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.2739 PIP4P2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55512 SAMD14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22437 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H4-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null active transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null SSRP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94483 CTCF_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXJ2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45178 ZNF559 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51874 PU.1-20513432-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ST6GALNAC6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6251 SETD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75208 AACS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48736 Central nervous system melanocytic neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.074 SARS-CoV MA15_Day7-PFU-10^2_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.9848 TTLL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.23845 amino acid transmembrane transport GO Biological Process Annotations 2023 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.895835 Polyhydramnios DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.383 USP44 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.92254 Liver hepatocellular carcinoma_LIHC_TCGA-EP-A3JL-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EWSR1-FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 144.457 hsa-miR-4735-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 cloh GeneRIF Biological Term Annotations 1.0 null RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10749 posteroventral (inferior) parietal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.845083 SUPT6H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68747 STK11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82039 Excretory canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.513 Podosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.888 r5 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58974 CHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43074 tuberomammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.79904 METTL13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44323 thyroid GTEx Tissue Gene Expression Profiles -1.0 -0.901491 SW579 CCLE Cell Line Gene CNV Profiles -1.0 -1.85782 MECR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.30218 ZNF140 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.7446 GSE124410_6_v_0_stk40_mouse RummaGEO Gene Perturbation Signatures 1.0 null Lef1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.4172 cerebellar white matter Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42005 peduncular nucleus of the stria medullaris Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00747 mRNA_TCF7L2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Lung adenocarcinoma_LUAD_TCGA-73-4677-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRTC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42581 MAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78632 PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-h-Classification_of_camel_SON_basal_genes_-_transporters_SON Rummagene Transcription Factor Associations 2026 1.0 null vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.05313 central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.225144 OCUG1 DepMap CRISPR Gene Dependency 1.0 2.25207 schizophrenia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.157765 hsa-miR-4419b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 intermediate stratum of DgSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.4329 ZR7530 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.893001 posterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.25896 hsa-miR-4700-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 parabigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.30586 ZNF334 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7893 ALDH3A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73839 lateral nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.848881 anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.88525 hsa-miR-3165 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 Purkinje cell layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61383 Cortical amygdalar area, posterior part, lateral zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.57397 Integral component of organelle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.102 GSE109913_1_v_2_bleomycin_mouse RummaGEO Drug Perturbation Signatures 1.0 null blood vessel TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053753 H4C14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28202 neutral amino acid transport GO Biological Process Annotations 2015 1.0 null DMBX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06609 secondary active transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Primary cell wall COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.216 mantle zone of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88114 Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.863 MRPL55 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61702 Renal tubular transport disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.017 GSE167886_3_v_1_chd7_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lung adenocarcinoma_LUAD_TCGA-38-4632-11A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-QH-A65R-01A-21R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Gravid adult TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.958 Phagocytic cup COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.574 glycine transport GO Biological Process Annotations 2015 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5LR-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.914785 frontal pole, right, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.74673 PPARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9884 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.180652 Major island of Calleja Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55513 Lung disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.863 mantle zone of Mam Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37822 g8 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.856 NUP58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07763 primary auditory cortex (core)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.951252 SSH3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31017 single-organism localization GO Biological Process Annotations 2015 1.0 null lysosome LOCATE Predicted Protein Localization Annotations 1.0 null PGM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00267 OAZ2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55022 GSE134191_3_v_5_metformin_mouse RummaGEO Drug Perturbation Signatures 1.0 null SIM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56181 r1 part of dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08826 cognitive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.048278 SUCO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82469 congenital heart disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.410535 emboliform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.48108 lateral part of MM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65208 OPM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.8066 monoatomic cation transmembrane transport GO Biological Process Annotations 2023 1.0 null mRNA_NANOG_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Ar JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.5844 deep layers of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08199 Larval brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.075 PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null CEBPB-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Integrin alphav-beta5 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.794 KO52 CCLE Cell Line Gene CNV Profiles -1.0 -2.23524 eye TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056508 ZNF829 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42624 SEC23B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34472 Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null integral component of membrane GO Cellular Component Annotations 2015 1.0 null SLC25A35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82524 BACE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45814 core of T-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27621 KMS20 DepMap CRISPR Gene Dependency 1.0 2.24912 DESI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40563 TBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4025 OSR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5102 SET-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.50514 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A905-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null perimammillary part of PHyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13758 ART5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40507 LARP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85863 ACAA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21129 LGALS3BP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87177 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IG-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CYB5RL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.39249 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81E-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Piriform-amygdalar area, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2142 endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null layer 4 of PaS Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02194 dorsal lateral geniculate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.4481 Sarcoma_SARC_TCGA-3B-A9HI-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null L-alanine transmembrane transporter activity GO Molecular Function Annotations 2023 1.0 null GSE111102,GSE111105_3_v_0_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null Inflammatory bowel disease GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.45229 intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null Foxo1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.9962 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.81946 testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 r2 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.8873 SALL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82052 fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.96101 L-amino acid transport GO Biological Process Annotations 2025 1.0 null C1GALT1C1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12391 stratum lacunosum-moleculare of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.83448 glycine-tRNA ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.689 MSC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7715 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6MF-01A-12R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A65E-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DOT1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55636 vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.08728 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MV-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Z disc COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.436 Interpeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20466 YWHAQ CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1702 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02076 POLM CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48277 vacuolar membrane GO Cellular Component Annotations 2025 1.0 null C8orf58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77473 mediodorsal nucleus of thalamus_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.830569 hsa-miR-3202 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 HCC364 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16486 ZBTB46 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11342 Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z5-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTPBP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07183 male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CHD1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KMS-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.67503 Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1435 CCLE Cell Line Gene CNV Profiles -1.0 -1.38946 dexamethasone_homo sapiens_gpl4133_gse42619 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Distal tip cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.076 REPIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09478 POTEF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60589 ZNF146 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23078 hsa-miR-3942-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.199275 LU-139 COSMIC Cell Line Gene Mutation Profiles 1.0 null VIIIA, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.46608 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A69L-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CCDC92B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50248 NCIH1781 CCLE Cell Line Gene CNV Profiles -1.0 -2.30004 Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 medial mammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86399 Spadix TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.994 RPMI 8226 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18842 transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null GSE245407,GSE245412_0_v_1_smurf1_human RummaGEO Gene Perturbation Signatures -1.0 null CLCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17448 amygdalo-striatal transition Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03797 Superior central nucleus raphe, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0223 biological_process GO Biological Process Annotations 2015 1.0 null GSE229671,GSE229673_2_v_1_yrdc_human RummaGEO Gene Perturbation Signatures -1.0 null MJ DepMap CRISPR Gene Dependency 1.0 5.19717 GSE112860_5_v_8_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null PROSER3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57375 retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.1166 parolfactory gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.07333 Brain Lower Grade Glioma_LGG_TCGA-P5-A5EU-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CORT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08633 Coelomocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.925 toxic encephalopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.191719 plant reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.34334 NKRF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93395 acid GeneRIF Biological Term Annotations 1.0 null ventrolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.892795 GSE182680,GSE182683_7_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null CERK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13949 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3BZ-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PFN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05981 posterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16886 EFF-1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.154 UQCRH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49168 ARF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48558 Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41R-01A-21R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MGRN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5081 TMED4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55973 EFR3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53318 GSE181821_1_v_3_mov10_mouse RummaGEO Gene Perturbation Signatures 1.0 null AP2A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.00594 solute:proton symporter activity GO Molecular Function Annotations 2023 1.0 null Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.08329 PSPH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88854 CXCR7_Deficiency_GDS3183_604_mouse_Neonatal semilunar valves GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null P2URK562 DepMap CRISPR Gene Dependency 1.0 11.9776 VTI1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94082 VZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.897322 internal granular layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39565 IDH2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55992 retrohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0169 CDX2-21402776-INTESTINAL-VILLUS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PARD6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02729 VRK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68677 Rectum adenocarcinoma_READ_TCGA-AH-6549-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.69792 anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.83377 JDP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7412 SOX30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92922 TEP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40646 NFKB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03179 H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null MZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21159 COMMD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52471 H3K36me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral part of Lat Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66776 mediodorsal nucleus of thalamus_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15215 CHD1 ENCODE Transcription Factor Targets 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZA-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H510A COSMIC Cell Line Gene Mutation Profiles 1.0 null NTS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79227 GSE132948,GSE132949_2_v_5_msi2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE88819_0_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null EIF2AK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71722 SK-BR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.83702 hsa-miR-4652-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 ATPAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60504 DHFR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99564 HCC2688 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.82301 Autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.05 AN3 CA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.902613 intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Anterior hypothalamic nucleus, central part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52538 Paraventricular hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.81539 superficial stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49409 Supramammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3301 primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.949763 MIEN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89397 FAM83F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53553 Edinger-Westphal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.9156 Leukocyte adhesion deficiency 3 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.272 PDHB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81637 Piriform-amygdalar area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37616 intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null USP49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24793 COPRS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.01209 Male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 MLKL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83276 Mr TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.128 GSE132948,GSE132949_2_v_3_msi2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PARP16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41533 CTTNBP2NL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0107 Acute Myeloid Leukemia_LAML_TCGA-AB-2872-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null temporal pole, left, medial aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.16709 Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null principal sensory nucleus of trigeminal nerve Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31931 skeletal muscle HPA Tissue Protein Expression Profiles 1.0 1.70596 ZNF876P CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93129 JcPV part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1737 HTT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03549 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6942-01A-21R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Uterine seam cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.102 paraventricular nucleus, peduncular or principal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.83787 Flocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.43694 ANKS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.9295 VDAC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.9268 peripheral neuropathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.387423 GSE182680,GSE182683_7_v_2_dexamethasone_human RummaGEO Drug Perturbation Signatures -1.0 null ANG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04961 Obstructive lung disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.863 COX18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25957 GSE211931_0_v_3_ncoa4_mouse RummaGEO Gene Perturbation Signatures 1.0 null Crus 2, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54647 lysosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.179459 IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.940628 Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SF-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatal amygdala Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06728 Early phagosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.779 Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30451 Cortical amygdalar area, posterior part, medial zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05654 PROKR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11978 TEAD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79216 KMRC2 CCLE Cell Line Gene CNV Profiles 1.0 1.63298 solute:proton symporter activity GO Molecular Function Annotations 2015 1.0 null Costamere COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.585 neutral L-amino acid transmembrane transporter activity GO Molecular Function Annotations 2025 1.0 null hsa-miR-3978 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 central part of VMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21317 hippocampus (hippocampal formation)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02883 dorsal tuberomammillary nucleus, intermediate part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67561 Ikzf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.53 GSE241701_1_v_0_daxx_mouse RummaGEO Gene Perturbation Signatures -1.0 null Uterine Carcinosarcoma_UCS_TCGA-NA-A4R0-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZC4H2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18487 RUNX1-20887958-HPC-7-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Amino acid transporter, transmembrane InterPro Predicted Protein Domain Annotations 1.0 null organic anion transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null Tcf21 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.4278 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FU-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LIN37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.35285 Dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18623 C8orf76 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32861 Cortical amygdalar area, posterior part, lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25269 ITGB5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.79068 cation transmembrane transport GO Biological Process Annotations 2015 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A3-11A-11R-A22L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-69-8253-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE148066,GSE157787_8_v_7_n4bp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null outer SZ in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10066 Glycoprotein network COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.374 piccolo-bassoon transport vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.764 hippocampus (hippocampal formation)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.1283 cortico-medial group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.93838 Paramedian lobule, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.93699 HS571T CCLE Cell Line Gene CNV Profiles -1.0 -2.07318 PSAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25865 molecular_function GO Molecular Function Annotations 2015 1.0 null cation:amino acid symporter activity GO Molecular Function Annotations 2015 1.0 null POM121C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.48315 MCOLN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07621 organelle LOCATE Predicted Protein Localization Annotations 1.0 null CTSL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23393 VENTX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32188 posteroventral (inferior) parietal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.93712 hippocampus (hippocampal formation)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02581 GUF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57822 FOXA1-21915096-LNCAP-1F5-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K27me3_Fetal Heart Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BPH1 DepMap CRISPR Gene Dependency 1.0 2.42363 r4 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.83577 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GY-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA3-26560356-CHIP-SEQ-TH1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SOX14 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.1696 PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null PEX5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60337 Brain Lower Grade Glioma_LGG_TCGA-HT-A618-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PLXND1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50865 lateral septal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.875063 QTRT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59371 Mesothelioma_MESO_TCGA-TS-A7P0-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE195559_6_v_4_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null IFNGR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74611 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6AW-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRUNE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44915 cell part GO Cellular Component Annotations 2015 1.0 null COLO-818 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02965 SMARCAL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17038 DIPK2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52041 amygdaloid complex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.980886 layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03729 IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29933 primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.944326 Lung adenocarcinoma_LUAD_TCGA-86-8585-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GRHL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63941 PUSL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40921 Lung adenocarcinoma_LUAD_TCGA-97-8174-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lytic vacuole LOCATE Predicted Protein Localization Annotations 1.0 null proton transmembrane transport GO Biological Process Annotations 2025 1.0 null KNS-42 COSMIC Cell Line Gene Mutation Profiles 1.0 null AU565 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.806988 superficial stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80881 subparafascicular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.865866 NCIH292 DepMap CRISPR Gene Dependency 1.0 4.06348 AR-22383394-PROSTATE-CANCER-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Sox7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.7182 RASL10B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67902 Kidney Chromophobe_KICH_TCGA-KN-8432-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZBTB22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84917 EZH2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-1305 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE172146_2_v_0_mettl1_human RummaGEO Gene Perturbation Signatures 1.0 null CPNE3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50773 Prostate adenocarcinoma_PRAD_TCGA-EJ-7784-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.439507 DDX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8463 MHH-NB-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29216 posteroventral (inferior) parietal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.94047 SP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07507 G-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null PSS008 DepMap CRISPR Gene Dependency 1.0 3.04142 Lung squamous cell carcinoma_LUSC_TCGA-63-A5MV-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null neutral amino acid transport GO Biological Process Annotations 2025 1.0 null Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.585 ZNF658 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62414 primary motor cortex (area M1, area 4)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.896232 MIB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4065 ST486 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null 928 MEL Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18751 caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.15246 M band COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.012 PPIC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29342 supramarginal gyrus, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24005 C3orf62 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82378 NTERA-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01421 outer CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.68313 H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Growth cone membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.544 OARD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53019 COX5A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56579 EP300 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9591 ITGB1BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99918 inner SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.72268 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.937498 Prostate adenocarcinoma_PRAD_TCGA-G9-6333-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU349 CCLE Cell Line Gene CNV Profiles 1.0 2.89061 VI, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.31734 VIIIB Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.89192 TUSC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53095 PMC9578714-elife-81083-supp2.xlsx-AA_Transporters-Common_Name_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null posterior tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32754 Cuticle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.325 IKZF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09307 Integrin alphav-beta8 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.704 solute:cation symporter activity GO Molecular Function Annotations 2015 1.0 null GSE195559_2_v_4_notch1_human RummaGEO Gene Perturbation Signatures -1.0 null icSARS-Cov_Day2_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.90067 BTBD17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55808 H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1581 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.5568 laminin-8 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.638 Lung adenocarcinoma_LUAD_TCGA-55-6975-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EDC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67639 Hand1::Tcf3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.5517 Sarcomere COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.493 Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.205 NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26155 NB7 DepMap CRISPR Gene Dependency 1.0 4.78254 piriform cortex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.857384 Muscle tendon junction COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.224 Brain Lower Grade Glioma_LGG_TCGA-HT-8011-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-A75M-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-587 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 nucleus of the stria terminalis, medial division, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42338 mantle zone of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.83577 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Ventromedial hypothalamic nucleus, dorsomedial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35755 PLB985 CCLE Cell Line Gene CNV Profiles 1.0 1.34618 TMEM41B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.77594 SKBR3 CCLE Cell Line Gene CNV Profiles 1.0 1.88044 JAK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61152 temporal pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.24047 MON DepMap CRISPR Gene Dependency 1.0 3.07674 hsa-miR-3689a-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.517189 whole plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.4634 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.30234 PU.1-20513432-BCELLS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null A101D COSMIC Cell Line Gene Mutation Profiles 1.0 null fruit TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.344079 SRMS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54682 periventricular stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.212 Prostate adenocarcinoma_PRAD_TCGA-EJ-A46E-01A-31R-A250-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE82104,GSE82299_1_v_0_acriflavine_human RummaGEO Drug Perturbation Signatures -1.0 null Perturb_14847_KD_PEG10_SRP055517 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.88185 ZNF239 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.73922 HNF4G JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.0047 PLIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0881 C11orf71 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18014 RDX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56506 U-937 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.914344 GZF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.07103 SPCS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7594 NKX1-1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24709 FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.040732 vacuolar part GO Cellular Component Annotations 2015 1.0 null PGLS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55631 GSE218907_3_v_2_opa1_mouse RummaGEO Gene Perturbation Signatures -1.0 null CDV3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48622 hsa-miR-4709-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 ZNF486 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.05111 cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.068588 stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.1183 stimulates GeneRIF Biological Term Annotations 1.0 null Integral component of endoplasmic reticulum membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.223 NPAS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21727 facial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.3067 organic anion transport GO Biological Process Annotations 2015 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K7-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MEOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80627 precentral gyrus, right, bank of the precentral sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.50824 CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07259 RALBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53416 periventricular stratum of AStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0391 H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteromedial cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1314 ZMYND19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.99101 CC2D1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61403 ZNF317 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5879 intracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.046573 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040544 TE-5 COSMIC Cell Line Gene Mutation Profiles 1.0 null CDC42BPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.1989 nucleus accumbens TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.289582 GSE211226_1_v_0_sirpa_mouse RummaGEO Gene Perturbation Signatures -1.0 null early-onset myopathy-areflexia-respiratory distress-dysphagia syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.104 NRDC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15456 METTL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96023 Rectum adenocarcinoma_READ_TCGA-AH-6547-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null molecular layer of CbHCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.4013 Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.2122 TNRC6C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42013 Esophageal atresia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.178 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02037 PCYOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.37162 HTRA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10193 psychotic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.077507 proton transmembrane transport GO Biological Process Annotations 2023 1.0 null POU2AF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11033 Perturb_16679_KO_SiglecE_SRP350344 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.0852 PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null carboxylic acid transport GO Biological Process Annotations 2025 1.0 null PHC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51546 ZSCAN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92109 Rectum adenocarcinoma_READ_TCGA-F5-6465-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null t69-brown-adipose_female_4w MoTrPAC Rat Endurance Exercise Training -1.0 -3.29349 Prostate adenocarcinoma_PRAD_TCGA-G9-6365-11A-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null Tooth agenesis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.055 HDAC2 ENCODE Transcription Factor Targets 1.0 null intracellular part GO Cellular Component Annotations 2015 1.0 null H3C2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98491 hsa-miR-4478 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Brain Lower Grade Glioma_LGG_TCGA-DB-A64X-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11495 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5365-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null M040416 DepMap CRISPR Gene Dependency 1.0 2.23199 BHLHE40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28463 layer III of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.6083 LCN12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03545 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7301-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PAPOLB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84448 periodontal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.234573 hsa-miR-4257 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 GSE200673,GSE200691_2_v_0_hmga2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE233679_6_v_8_nicotinamide_human RummaGEO Drug Perturbation Signatures -1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ED-A66Y-01A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Entorhinal area, medial part, ventral zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23795 FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.4454 Sox5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.1048 EIF4E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.47933 Cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.32328 CCN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.04704 ZDHHC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5661 USP54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.18432 ST6GALNAC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05547 SG in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.833207 gonad TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null SLC11A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49003 GSE88819_5_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null MFSD14B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.1538 SCAF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29522 interstitial nucleus of Cajal, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.02442 GSE124410_3_v_0_stk40_mouse RummaGEO Gene Perturbation Signatures 1.0 null SLC24A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41991 medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.95117 RV16_0Hour-B2B_None_GSE28904 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.08255 SFT2D1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83546 hippocampus (hippocampal formation)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.864116 Acute Myeloid Leukemia_LAML_TCGA-AB-2833-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null H4C8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99858 ZNF547 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.7529 mammillary part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37764 r2 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.86888 bronchus HPA Tissue Protein Expression Profiles 1.0 0.895746 CA12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9781 SEMA7A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76293 BACH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.0622 WDR75 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22282 YY1 MotifMap Predicted Transcription Factor Targets 1.0 null peduncular part of dorsomedial hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.82277 External female genital organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.755 BAG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05322 SZ in rostral cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.951802 496100375_FWM_dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.53092 ZNF16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 54.7527 GCM2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.6416 prepositus hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.866455 H3K9me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SEPTIN7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22873 PTGR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30306 Nanog JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.1332 UGT3A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4249 SW 1116 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.2121 p2 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.62 Brain Lower Grade Glioma_LGG_TCGA-FG-A60K-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AGFG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37219 Cochlear nucleus, subpedunclular granular region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.77525 TRAPPC13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.45967 Vacuolar membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 CAL-85-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.855386 SUDHL4 DepMap CRISPR Gene Dependency 1.0 2.19443 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3975 dorsomedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.15102 Paraventricular hypothalamic nucleus, parvicellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.91004 alanine transport GO Biological Process Annotations 2025 1.0 null CHRNA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08401 ENAH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51182 hsa-miR-1290 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 H2AFZ ENCODE Transcription Factor Targets 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FKBP7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82367 OVCAR-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35352 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.43375 FOSL2::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9698 Dense body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.255 magnocellular interstitial nucleus of the posterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43229 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NG-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAFK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4636 RBCK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01482 HCC1954 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.659417 GSE112860_5_v_7_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null Paramedian lobule, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.28873 UBE2NL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6385 VI Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.919035 AARD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65091 transporter activity GO Molecular Function Annotations 2015 1.0 null slc26a6 GeneRIF Biological Term Annotations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-CH-5767-11B-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAMA1 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.47665 Pollen wall COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.797 Arbuscule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.558 H2AC15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13823 CENPT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17561 CLASRP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93361 GSE144443_0_v_1_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null cytoplasmic part GO Cellular Component Annotations 2015 1.0 null MAFK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05193 NIPBL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70421 bed nucleus of the stria terminalis, medioseptal division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07911 muscular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.051757 Hypodermal seam cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.757 NAGLU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24471 hsa-miR-4799-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 EXOSC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02704 f95 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.039 GSE88819_7_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null DGKK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92534 hsa-miR-376a TargetScan Predicted Conserved microRNA Targets 1.0 0.31417 nfe2l2_23639809_whole_esophagus_lof_mouse_gpl7202_gse39629 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 1.52859 NCI-H2171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.00344 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5374-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.21383 BANF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75243 DCANP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13289 Perturb_11917_KO_Apoe_SRP135284 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.5264 NT5DC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94291 amygdaloid complex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.41865 Coelomic fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.903 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DW-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tendril TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.827 Protonema TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.24 Protein digestion and absorption KEGG Pathways 2026 1.0 null SMAD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87791 INA complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.963 glycine transport GO Biological Process Annotations 2023 1.0 null lytic vacuole COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.179459 localization GO Biological Process Annotations 2015 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.412771 ITM2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2565 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Lung adenocarcinoma_LUAD_TCGA-75-5122-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.949763 photoreceptor TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.223906 mediodorsal nucleus of thalamus_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.22164 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BS-01A-21R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXO4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2322 NLGN4Y CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78852 ChIP_YY1_21170310 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE94849_6_v_0_pinometostat_human RummaGEO Drug Perturbation Signatures 1.0 null VAX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.70224 inorganic cation transmembrane transport GO Biological Process Annotations 2015 1.0 null stomach BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.25634 NCI-H1648 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.895519 LS1034 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.842224 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.497 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5369-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE119978,GSE180930_2_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null superficial stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27384 Basomedial amygdalar nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0788 Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATP5MC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.56087 Ventromedial hypothalamic nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.93173 CARNMT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.70561 AGO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77238 Microspore TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.012 Prostate adenocarcinoma_PRAD_TCGA-HC-7078-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nucleus of the stria terminalis, medial division, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01547 amino acid:monoatomic cation symporter activity GO Molecular Function Annotations 2023 1.0 null SRY-25088423-EMBRYONIC-GONADS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE143782_6_v_5_calcitriol_human RummaGEO Drug Perturbation Signatures 1.0 null PNP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.8152 Lung adenocarcinoma_LUAD_TCGA-38-4626-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EBLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43944 SKMEL2 DepMap CRISPR Gene Dependency 1.0 2.19405 OAW42 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00515 MUTZ8 DepMap CRISPR Gene Dependency 1.0 2.07113 H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.47642 muscle tissue disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.052455 KPNB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42233 parvicellular interstitial nucleus of the posterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09793 SARM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.88645 FIS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22744 IKZF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.663 PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2 Rummagene Transcription Factor Associations 2026 1.0 null brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051314 Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.117 HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.854422 intermediate stratum of PHyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.88664 ZNF671 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42833 suprachiasmatic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.29986 COLO668 CCLE Cell Line Gene CNV Profiles -1.0 -1.34149 TRIM25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19522 FAM200A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.60822 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3Y4-01A-51R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43181 SMC1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.24677 NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50594 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null medial mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.91813 autosomal recessive disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.049082 SR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22187 reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null DDX11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.43478 GSE245134_2_v_3_atg5_mouse RummaGEO Gene Perturbation Signatures -1.0 null PKIG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83658 amino acid:proton symporter activity GO Molecular Function Annotations 2023 1.0 null NCI-H2081 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.53865 intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.044011 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.19068 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KNS42 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 epithelial GeneRIF Biological Term Annotations 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7XP-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7687-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7858-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FKBP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.61221 mantle zone of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.86965 Respiratory system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.863 ANKMY2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75607 hsa-miR-3975 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 Ansiform lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28342 DDT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.03755 Hic1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.1553 RIOK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75027 STAC3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32101 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A6QX-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null single-organism process GO Biological Process Annotations 2015 1.0 null Central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.155 membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.046427 TRMO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94743 GSE214212_2_v_0_chd6_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null L-amino acid transport GO Biological Process Annotations 2023 1.0 null SDHAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79703 WDCP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.45193 TBX22 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.00308 ZBTB26 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4942 CTSF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4286 H3K27me3_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null multiform (lateral) division of MD Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.45546 Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HV-06A-21R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.14762 Female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PLEK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44204 COLO 679 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0423 PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33781 L-1236 COSMIC Cell Line Gene Mutation Profiles 1.0 null alanine transport GO Biological Process Annotations 2023 1.0 null intermediate stratum of AStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0799 Gut granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.511 Uterine anchor cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.634 LIN54 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.38715 Brain Lower Grade Glioma_LGG_TCGA-S9-A6WD-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VIIB, right, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.931055 Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QW-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Anterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38115 Acute Myeloid Leukemia_LAML_TCGA-AB-2954-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LMO2-20887958-HPC-7-MOUSE ChEA Transcription Factor Targets 2022 1.0 null paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.917416 SET2 DepMap CRISPR Gene Dependency 1.0 3.31988 myopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.052833 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RUNX1 ChEA Transcription Factor Targets 1.0 null Myoepithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.89 ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.0941 SLC2A8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95496 NCIH1648 CCLE Cell Line Gene CNV Profiles 1.0 1.6514 Adrenocortical carcinoma_ACC_TCGA-PK-A5H8-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.3301 Lung adenocarcinoma_LUAD_TCGA-97-8176-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Basomedial amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02343 HRC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93944 Gonad TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 DENND4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57904 HT144SKINFV2 DepMap CRISPR Gene Dependency 1.0 3.96889 TCF7L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.05123 GLIS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99486 periventricular stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0169 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A7PW-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CGB7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02565 Caulonema TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.479 Kidney Chromophobe_KICH_TCGA-KO-8408-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MCM core complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.67 trachea TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.278251 glycine transmembrane transporter activity GO Molecular Function Annotations 2025 1.0 null Vertebrate muscular system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Basal plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.73 H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MRPL52 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.06382 PEDS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65268 cellular_component GO Cellular Component Annotations 2015 1.0 null periventricular stratum of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04484 PXDN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25653 heart muscle HPA Tissue Protein Expression Profiles 1.0 0.895746 Hemispheric regions Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45982 striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.924961 ZNF587B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46631 IFIH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31526 organic acid transport GO Biological Process Annotations 2015 1.0 null V, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.15085 shoot TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.065736 dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10823 transport GO Biological Process Annotations 2015 1.0 null SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null KS-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Ventral nerve cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.568 r1 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.33218 SET2 CCLE Cell Line Gene CNV Profiles -1.0 -1.66279 mp3 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.565 Meningeal melanomatosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.172 ACAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74478 Uterine epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.653 dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.80149 apical GeneRIF Biological Term Annotations 1.0 null Lung adenocarcinoma_LUAD_TCGA-97-A4M2-01A-12R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MCHR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74625 proline transmembrane transport GO Biological Process Annotations 2025 1.0 null amino acid transmembrane transport GO Biological Process Annotations 2015 1.0 null ORMDL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46607 IFT122 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81043 ELP6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84454 SPI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null RAB14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.90802 THAP12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.6352 Kenyon cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.255 VPS11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54107 PFEIFFER Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.11194 PRKDC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54676 NFATC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1385 MYT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.29119 artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057013 SMAD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07061 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-485-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 transverse gyri, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.973986 TIGD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15069 EME1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06658 Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M6-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNRPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56577 G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.41653 PIAS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.54088 KURAMOCHI COSMIC Cell Line Gene Mutation Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-XS-A8TJ-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF652 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1241 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A8O6-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA3-20176728-TROPHOBLAST STEM CELLS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null NCI-H716 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07259 SLC22A5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0174 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EK-01A-12R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AGFG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5213 tooth disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.192031 PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D Rummagene Transcription Factor Associations 2026 1.0 null rostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15068 posteroventral (inferior) parietal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.51171 RTCA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01286 outer CP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.969627 RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06467 membrane GO Cellular Component Annotations 2015 1.0 null Subdural space TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.067 heart disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.157765 Junctional epidermolysis bullosa non-Herlitz type DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.217 paraventricular nucleus, cap part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29819 NCIH209 CCLE Cell Line Gene CNV Profiles -1.0 -2.00109 CCDC97 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19469 rhombomere 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20459 BAD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95795 GSE100863,GSE100864_3_v_0_tet2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.215 dorsolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.928012 mouth disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.165435 ANAPC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15227 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CL-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YA-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ROS50 DepMap CRISPR Gene Dependency 1.0 5.17693 CoPV part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18825 PWWP2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7444 ZNF93 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7929 CALU-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43438 FOSL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.71 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04028 globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13962 TENM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21929 PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.957016 outer plexiform zone in extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.13736 Glycoprotein Ib-IX-V complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.392 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null post-anaphase microtubule array COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.787 hydrogen:amino acid symporter activity GO Molecular Function Annotations 2015 1.0 null SARS-CoV MA15_Day1-PFU-10^2_None_GSE33266 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.95758 posteroventral (inferior) parietal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.28877 Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A9DB-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superior parietal lobule, left, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00675 SOX13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7687 RIF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06445 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ACOT8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07038 ventrolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.67206 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.28902 SOWAHD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.42698 ZNF85 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19892 SH3GLB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69872 Prostate adenocarcinoma_PRAD_TCGA-KK-A8IK-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OS9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.06578 Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.673 BMP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44319 8505C DepMap CRISPR Gene Dependency 1.0 2.24107 496100514_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.48127 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043644 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A431-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1305 DHCR24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.85564 DCUN1D2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76639 ZFYVE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99046 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EJ-11A-11R-A155-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PEG10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40482 TUSC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9587 MT-CO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55461 hsa-miR-659 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 molecular layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.957302 internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null IZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00551 Lung adenocarcinoma_LUAD_TCGA-93-A4JN-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRIM46 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14136 Sarcoma_SARC_TCGA-3B-A9HQ-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-LT-A5Z6-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null core part of the anterobasal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30596 GSE88819_6_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Superior central nucleus raphe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07693 SIX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4052 SNCB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25335 TP53BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82255 disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.041265 periodontitis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.30342 EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.917525 integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 periventricular stratum of TPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66128 gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null hsa-miR-1264 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 Pollen tube TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.248 HDLM2 CCLE Cell Line Gene CNV Profiles -1.0 -1.51631 ACSM2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.81546 ventrolateral prefrontal cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.04577 hsa-miR-516b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 DPP9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12565 Lung adenocarcinoma_LUAD_TCGA-55-6969-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CBY3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80036 Prostate adenocarcinoma_PRAD_TCGA-HC-7745-01A-11R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFIL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57125 acute myocardial infarction DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.552075 testis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-8299-01A-11R-2287-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null IZ in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.95089 Deutocerebrum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.099 r3 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.74584 cerebellar cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.842934 UXS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47327 496100473_TCx_possible Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.12177 JHOS4 CCLE Cell Line Gene CNV Profiles 1.0 1.86076 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7048-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterolateral cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2742 ABI3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36399 CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.965472 Acute Myeloid Leukemia_LAML_TCGA-AB-2818-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GR-M Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.61143 intermediate stratum of Mam Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86399 SKNEP1 DepMap CRISPR Gene Dependency 1.0 2.38698 Hypothalamic medial zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06083 EPHA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.65462 mammillary body, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.66069 NSMF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15958 Crus I, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.05321 HT3 DepMap CRISPR Gene Dependency 1.0 2.20918 Root hair COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.017 N4BP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34813 cingulate gyrus, parietal part, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.846525 monovalent inorganic cation transport GO Biological Process Annotations 2015 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5441-01A-01R-1514-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-A87Q-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KIF4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27838 Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09902 NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1305 Dorsomedial nucleus of the hypothalamus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.32453 LPS510 DepMap CRISPR Gene Dependency 1.0 2.81129 core of P-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64331 GSE208171_0_v_1_zc4h2_human RummaGEO Gene Perturbation Signatures 1.0 null posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.12768 FUBP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10576 Skin Cutaneous Melanoma_SKCM_TCGA-FR-A726-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DDIT4L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.59285 lateral subdivision of area 9 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.66629 Fruit capsule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.877 ARFGEF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18218 Lung adenocarcinoma_LUAD_TCGA-05-4425-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ATF6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3833 superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.662 myocardial infarction DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.30848 posteroventral (inferior) parietal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.50897 UBR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15938 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2ME-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A5QV-01A-22R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW1088 CCLE Cell Line Gene CNV Profiles 1.0 1.33121 neutral L-amino acid transmembrane transporter activity GO Molecular Function Annotations 2023 1.0 null TGOLN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.59612 organelle membrane GO Cellular Component Annotations 2015 1.0 null Larva TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.57 CITED2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0504 KCTD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93172 r7 part of the posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49409 hsa-miR-4667-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 HNF4A JASPAR Predicted Transcription Factor Targets 1.0 null ELMOD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47673 PARP14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41659 RNA polymerase II termination complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.555 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ALDH9A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.57535 Hypodermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.804 HCC1493 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.830246 Dorsal nerve cord TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.841 LO68 DepMap CRISPR Gene Dependency 1.0 2.09351 ITM2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31665 Perturb_3915_KD_CTNNB1_DRP003300 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.30842 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.276495 Shoot apical meristem TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.981 AGBL5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25004 SG in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.98249 Adrenocortical carcinoma_ACC_TCGA-OR-A5JP-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FBF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41942 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null inferolateral temporal cortex (area TEv, area 20)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.43866 amino acid transport GO Biological Process Annotations 2015 1.0 null DiaA complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.906 solute:proton symporter activity GO Molecular Function Annotations 2025 1.0 null hsa-miR-3689c TargetScan Predicted Conserved microRNA Targets 1.0 0.568687 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.87301 ZNF35 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95296 TMEM69 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57438 EHBP1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71285 Integrin alpha9-beta1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.536 single-organism cellular process GO Biological Process Annotations 2015 1.0 null ZSCAN23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28891 genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042091 MAP4K3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.0307 BLACAT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.71428 AR-22383394-PROSTATE_CANCER-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.59262 Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1Q0-01A-21R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TMEM168 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.966 Brain Lower Grade Glioma_LGG_TCGA-S9-A6TW-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KCTD11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07083 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09493 AU565 CCLE Cell Line Gene CNV Profiles 1.0 1.58514 REP15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55643 H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null rostral interpeduncular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26763 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.95675 lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.832547 ZNF709 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50795 Posterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.81298 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-2687-01A-02R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.2114 hsa-miR-4781-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.598666 SG in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.69696 Kidney Chromophobe_KICH_TCGA-KO-8405-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AQP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.50822 dorsolateral prefrontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.958977 GSE119978,GSE180930_0_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE131588,GSE131690_1_v_0_setd2_mouse RummaGEO Gene Perturbation Signatures 1.0 null PCBP4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.19986 hsa-miR-583 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 mantle zone of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38862 Anterior hypothalamic nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.41858 H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null retromammillary area, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67561 CUX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68696 NCIH1963 CCLE Cell Line Gene CNV Profiles -1.0 -1.76343 Bed nucleus of the anterior commissure Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.88664 lateral ventricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.148811 ZNF638 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.55007 GLB1L3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.88995 EBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75615 ventromedial hypothalamic nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.45525 Nexine COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.985 ventrolateral prefrontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.859032 496100661_PCx_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.20548 hsa-miR-4425 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Liver hepatocellular carcinoma_LIHC_TCGA-5C-A9VH-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mediodorsal nucleus of thalamus_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.43043 G22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.0423 Kindler syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.797 transmembrane transport GO Biological Process Annotations 2015 1.0 null CEBPB-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE153484_2_v_0_foxp3_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCDN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64315 L-amino acid transmembrane transporter activity GO Molecular Function Annotations 2023 1.0 null Paramedian lobule Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.08449 mRNA_SOX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CDY2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.89653 Nr2f6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 51.0604 RCC4 CCLE Cell Line Gene CNV Profiles 1.0 1.92725 HEXA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.76108 r3 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.2108 A-427 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.842224 l-alanine transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07165 ESRRB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.41459 Lung adenocarcinoma_LUAD_TCGA-05-4384-01A-01R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8494348-pone.0257161.s002.xlsx-only_D20_-_OXT_NOT_ext-Gene_Name_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null Chloronema TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.735 MEL-JUSO COSMIC Cell Line Gene Mutation Profiles 1.0 null membrane part GO Cellular Component Annotations 2015 1.0 null Flower bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.838 vacuole LOCATE Predicted Protein Localization Annotations 1.0 null SPRR2F CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57296 ATP7B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47822 Leukocyte adhesion deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.217 G111 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.916307 TMEM132A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.03078 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ZSCAN16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.1261 USP21 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.30845 neutral amino acid transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null MM1S DepMap CRISPR Gene Dependency 1.0 2.10343 SARS-CoV MA15_Day2-C57BL6_None_GSE50878 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 0.91179 Prostate adenocarcinoma_PRAD_TCGA-M7-A71Y-01A-22R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BAMBI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.37152 Sarcoma_SARC_TCGA-DX-A6YR-01A-33R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CSF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48736 GNA13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.69803 lambdoid septal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23124 NDUFV3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85668 GMCL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18426 RFX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4176 MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.842224 Brain Lower Grade Glioma_LGG_TCGA-VM-A8CH-01A-12R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null amino acid transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null Rectum adenocarcinoma_READ_TCGA-AG-3591-01A-01R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Thoracic ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.974 GSE151494_10_v_3_nrp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null RET_mutant_23_GDS3319 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.74843 vacuolar membrane GO Cellular Component Annotations 2023 1.0 null SOX17-20123909-XEN-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Cco TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.765 CIAO3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76395 AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA ChEA Transcription Factor Targets 2022 1.0 null hsa-miR-3976 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 UCKL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16391 Umbilical cord blood cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.752 SOCS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.38532 SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22639 MED16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89232 SLC16A14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6463 ISCA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36115 mantle zone of AStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06655 mantle zone of PHyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13758 proline transmembrane transport GO Biological Process Annotations 2023 1.0 null Runx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.269 HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02037 JRKL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.3922 chr5_151303752_C_G_b38 GTEx eQTL 2025 1.0 1.02142 Cell body fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.651 CLIC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67258 H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41177 GCSH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53504 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null intermediate stratum of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67724 intercalated amygdaloid nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14054 WWP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89614 MAP2K7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95595 HCC4011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43181 periventricular stratum of PPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.83787 interpositus (intermediate) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.855313 THAP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52218 ENTREP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67309 DSTYK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23083 Piriform-amygdalar area, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50031 r4 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80953 VIIB, right, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.850662 Spz1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.9167 CAMA1 CCLE Cell Line Gene CNV Profiles 1.0 1.83113 BT-549 COSMIC Cell Line Gene Mutation Profiles 1.0 null Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30451 Anterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.93484 Brain Lower Grade Glioma_LGG_TCGA-DH-A7UV-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_bone marrow_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.972682 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null FOSB::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.9771 GLO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89491 ventrolateral prefrontal cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08933 mediodorsal nucleus of thalamus_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14483 OVCAR433 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.10749 TMEM89 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.94709 ZFP36L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55757 primary motor cortex (area M1, area 4)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.21062 496100552_PCx_possible Alzheimer's disease_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.79072 spleen GTEx Tissue Gene Expression Profiles 1.0 1.09547 IRF8-27001747-CHIP-SEQ-BMDM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null inferior frontal gyrus, triangular part, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.975532 GIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33838 PF-382 COSMIC Cell Line Gene Mutation Profiles 1.0 null Myoepithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.992 ZNF662 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74621 FOXA1-25552417-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Lower respiratory tract disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.863 MEF2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.3512 SMAD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.62336 Paraflocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.9665 urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.270561 HCC2218 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.147 midbrain reticular formation, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.12291 Lateral septal nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06926 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70V-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Craniodiaphyseal dysplasia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.012 KLF11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.21444 H1-10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14438 SRY ChEA Transcription Factor Targets 1.0 null DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27866 TAL1-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null LMO2 ChEA Transcription Factor Targets 1.0 null NR2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.7546 r5 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6057 RIDA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5089 Lung adenocarcinoma_LUAD_TCGA-55-7724-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.50668 ventrolateral prefrontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.33425 JUN::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.9751 Brain Lower Grade Glioma_LGG_TCGA-TM-A84L-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DMS153 CCLE Cell Line Gene CNV Profiles -1.0 -1.72733 NFATC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99758 Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Supramammillary nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51286 Intercalated amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06728 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K27me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A97P-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4782-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 fertilizedegg BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07371 GSE214823,GSE214824_0_v_1_crtc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Gli1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.7539 posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.23485 shell of P-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.84033 hippocampus (hippocampal formation)_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00846 organic acid transmembrane transport GO Biological Process Annotations 2015 1.0 null GOT1L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77042 BTG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80699 L-proline transmembrane transporter activity GO Molecular Function Annotations 2025 1.0 null PMC9284696__F2 PFOCR Pathway Figure Associations 2024 1.0 null anion transmembrane transport GO Biological Process Annotations 2015 1.0 null hsa-miR-4293 TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 GSE180277_0_v_1_bach2_mouse RummaGEO Gene Perturbation Signatures -1.0 null pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.951011 primary motor cortex (area M1, area 4)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.19605 Foxo3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.1761 hsa-miR-577 TargetScan Predicted Conserved microRNA Targets 1.0 0.212286 CPEB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32933 NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18842 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.842224 CEP85 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35077 PODXL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22438 KY821 COSMIC Cell Line Gene Mutation Profiles 1.0 null l-amino acid transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null GATA3 ChEA Transcription Factor Targets 1.0 null lmx1b_18351676_hind_limb_bud_lof_mouse_gpl1261_gds3320 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.026069 MESP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01087 HCC1171 CCLE Cell Line Gene CNV Profiles 1.0 1.65872 ECPAS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7001 mantle zone of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58877 Eggshell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.796 SELENBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2134 long insular gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.832675 Piriform-amygdalar area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58252 inorganic cation transmembrane transport GO Biological Process Annotations 2023 1.0 null Host cellular component COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.631 hsa-miR-485-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 H3K9me3_CH12.LX_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null Ebolavirus(ZEBOV)_3day_Liver_None_GSE57214 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.4018 Nerve ring TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.876 HAUS7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.48106 PL-21 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.895455 GSE211931_2_v_3_ncoa4_mouse RummaGEO Gene Perturbation Signatures 1.0 null MUS81 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.13617 MALME3M CCLE Cell Line Gene CNV Profiles -1.0 -1.51946 Acute Myeloid Leukemia_LAML_TCGA-AB-2971-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4717-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 SF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.7969 DMS79 CCLE Cell Line Gene CNV Profiles -1.0 -1.42882 Lung squamous cell carcinoma_LUSC_TCGA-85-A50Z-01A-21R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-38-4625-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.49228 ETV2-25802403-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE144443_5_v_1_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null oocyte BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.10692 paraventricular nucleus, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50722 KP4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02037 MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.99948 H3K27me3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organic cation transport GO Biological Process Annotations 2025 1.0 null intermediate stratum of THyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16036 amino acid:proton symporter activity GO Molecular Function Annotations 2025 1.0 null septohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.97455 IRF3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.855386 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19D-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VN-A88R-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051873 GCT CCLE Cell Line Gene CNV Profiles 1.0 1.60186 PML CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47101 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6R0-01A-12R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-35-5375-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HTR1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68669 DNAJC2 ChEA Transcription Factor Targets 1.0 null Epilepsy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.071 MARK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19005 MAFF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4305 Entorhinal area, medial part, ventral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16309 496100534_FWM_probable Alzheimer's disease_no TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.62008 Dorsal premammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37764 H3K27me3_CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null epidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.931844 ACTRT3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.4148 TRIM41 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.89181 H3K9me3_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Lateral plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.858 MAML3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24835 ML-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null known GeneRIF Biological Term Annotations 1.0 null 496100638_FWM_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.34744 MCL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01003 Skeletal muscle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NOL9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54545 NSD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65129 stratum oriens of rostral CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.837268 cystic fibrosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.235268 basomedial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17805 ventricular septal defect DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.783526 RUNX1-20887958-HPC-7-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GSE153871_1_v_3_cytarabine_human RummaGEO Drug Perturbation Signatures 1.0 null medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.82559 COLO-792 COSMIC Cell Line Gene Mutation Profiles 1.0 null NPEPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50886 cerebellar hemisphere Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38938 cation transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null ETV5::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5769 GSE133070_3_v_1_prss1_mouse RummaGEO Gene Perturbation Signatures -1.0 null BACH1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6624 Sarcoma_SARC_TCGA-MJ-A68J-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r1BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24048 membrane LOCATE Predicted Protein Localization Annotations 1.0 null Female pudendum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.759 anion transport GO Biological Process Annotations 2015 1.0 null establishment of localization GO Biological Process Annotations 2015 1.0 null CORL279 CCLE Cell Line Gene CNV Profiles -1.0 -1.32661 CDC25C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19913 PANC 04.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.914344 SAP30 ENCODE Transcription Factor Targets 1.0 null Zfp335 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.0833 HOMER3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61323 H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-502-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 carboxylic acid transmembrane transport GO Biological Process Annotations 2025 1.0 null symporter activity GO Molecular Function Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC4A11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03133 GATA3-20176728-TSCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null organic substance transport GO Biological Process Annotations 2015 1.0 null KG1C CCLE Cell Line Gene CNV Profiles 1.0 1.52844 FOSL1::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.5883 Brain Lower Grade Glioma_LGG_TCGA-DB-A75O-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SF3B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.41556 Mammillary body Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12203 L-alanine transport GO Biological Process Annotations 2025 1.0 null Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.252 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null DLX6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88418 Prostate adenocarcinoma_PRAD_TCGA-HC-8262-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.71218 GATA2-21186366-BM-HSCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HIRIP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19264 Adrenocortical carcinoma_ACC_TCGA-OR-A5KY-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE88819_1_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Subparaventricular zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.21649 single-organism transport GO Biological Process Annotations 2015 1.0 null NYNRIN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.31919 r4 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.87423 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DU4475 DepMap CRISPR Gene Dependency 1.0 4.73229 SAP30_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null substrate-specific transporter activity GO Molecular Function Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A737-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Granular lamina of the cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.65246 SGPL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22587 SRY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.31332 Yy1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.5017 TNRC6A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22434 rostral ventral respiratory cell group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.15636 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GN-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Jun JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.7397 LUC7L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01096 Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBCCD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72068 isolated GeneRIF Biological Term Annotations 1.0 null organic acid transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null M140325 DepMap CRISPR Gene Dependency 1.0 2.25284 lysophosphatidic GeneRIF Biological Term Annotations 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GX-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSTP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87093 RCN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44917 cell part LOCATE Predicted Protein Localization Annotations 1.0 null IL4R CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.79493 superficial stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.8873 paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10001 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.36848 FOSL2::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.448 PRRC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82262 RGP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83904 Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73748 Sox17 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.5709 Elf5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.1937 lateral hypothalamic area, tuberal region, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.00324 dorsalstriatum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.46902 SKIDA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02125 LZTS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9566 Iminoglycinuria DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.103 RMGI DepMap CRISPR Gene Dependency 1.0 2.66442 SNU410 CCLE Cell Line Gene CNV Profiles 1.0 2.30287 dorsolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.49607 Lung adenocarcinoma_LUAD_TCGA-62-A46Y-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WZ-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE152432_9_v_0_zrsr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Spermatheca TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.092 EIF3K CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23091 periventricular stratum of RMa Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67561 Sox3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.7803 NO36 DepMap CRISPR Gene Dependency 1.0 2.73936 alanine transport GO Biological Process Annotations 2015 1.0 null paraventricular nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3296 IZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31076 exchange GeneRIF Biological Term Annotations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U8-11A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12216174-41598_2025_6356_MOESM13_ESM.xlsx-Sheet1-Supplementary_Table_3_Classification_of_amino_acid_AA_transporters_at_four_different_subcellular_localizations_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null LRP5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19588 PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A183-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular organelle part GO Cellular Component Annotations 2015 1.0 null LACC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78201 extrinsic cardiomyopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.210253 Body wall muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.169 Amino acid transport complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.396 Paraflocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.65246 Striated muscle cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.695 496100374_HIP_possible Alzheimer's disease_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.84101 C2orf49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87266 ion transport GO Biological Process Annotations 2015 1.0 null NCIH510 DepMap CRISPR Gene Dependency 1.0 4.63704 Myelinating Schwann cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.66 Brain Lower Grade Glioma_LGG_TCGA-S9-A7QW-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null glycine transmembrane transporter activity GO Molecular Function Annotations 2023 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MU-06A-21R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XB-01A-11R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DDX20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6159 nucleus incertus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17213 C6orf226 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27733 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RH-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STOML1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92138 FXYD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68972 inorganic cation transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null C9orf40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15602 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKIC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31651 Kidney Chromophobe_KICH_TCGA-KN-8421-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pulmonary artery TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.233446 periventricular stratum of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21455 PAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.1679 HCC2157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.16486 TDP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.66024 NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.855386 ZCCHC18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21933 PMC9578714-elife-81083-supp2.xlsx-AA_Transporters-Gene_Name_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null TNIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09588 Gametophore TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.639 Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49444 Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4224-01A-01R-1436-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NPIPA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68293 rostral paraventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.66128 bounding membrane of organelle GO Cellular Component Annotations 2023 1.0 null HCC1599 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.13305 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.1305 ODF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.02435 TAB3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08256