association	dataset	threshold value	standardized value
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.0075
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Q7-1026-SM-4AD75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883632
SEKI	DepMap CRISPR Gene Dependency	1.0	4.98844
Colonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.764
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE124932_2_v_1_sarm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TIMM17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19948
CORL23	CCLE Cell Line Gene Expression Profiles	1.0	1.43208
CLDN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67134
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fungal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
Nucleus solitarius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.003
GTEX-R55G-0126-SM-48FDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K10301055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41308
Abnormal Oral Glucose Tolerance	DisGeNET Gene-Phenotype Associations	1.0	null
HT55	CCLE Cell Line Gene Expression Profiles	1.0	1.52396
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.756971
phosphorylation	GeneRIF Biological Term Annotations	1.0	null
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K87617154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00482
BRD-K56761719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24227
Hyperinsulinism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.172
Appendix	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31354
BRD-K86025005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02156
Golgi apparatus subcompartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.659
periventricular stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09017
Tricellular tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.95
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_TCF3_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.518072
Squamous Cell Carcinoma Of Tongue	DisGeNET Gene-Disease Associations	1.0	null
SLC25A15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1521
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.60384
C20orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51809
Mesenteric vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.827
pancreatic	GeneRIF Biological Term Annotations	1.0	null
GLUFOSFAMIDE	DGIdb Drug Targets 2026	1.0	0.389206
Bone resorption disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
BRD-K44936922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00153
all	HPO Gene-Disease Associations	1.0	null
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38697
LIVF001-019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67895
glucoside transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
poor	GeneRIF Biological Term Annotations	1.0	null
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46307
PMC7429792-40104_2020_487_MOESM3_ESM.xlsx-MSC_enriched_miRNA_target-NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Cholinergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75026
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.606
Bicellular tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.039
GSE237040_4_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
transcriptional	GeneRIF Biological Term Annotations	1.0	null
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K24734706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31677
Bromosuccinimide	CTD Gene-Chemical Interactions	1.0	null
G protein-coupled receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.96
5707885-6385	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K05181466	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1397
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040492
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RIE-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.563
GTEX-TMMY-1526-SM-4DXST	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
reabsorption	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4673	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
COPI-coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.017
LS513	CCLE Cell Line Gene Expression Profiles	1.0	2.25557
GSE109285_5_v_4_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CDK7_knockdown_138_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.84705
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38407
GSE246195,GSE246305_4_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2908
hsa-miR-4645-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Non-Small Cell Lung Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85786
increased bone trabecula number	MPO Gene-Phenotype Associations	1.0	null
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986293
CHRNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.705
20412141-Table1	GeneSigDB Published Gene Signatures	1.0	null
dietary	GeneRIF Biological Term Annotations	1.0	null
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.362
Nutritional deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Defective SLC5A1 causes congenital glucose/galactose malabsorption (GGM)	Reactome Pathways 2024	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.593
Microbody	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.793
release	GeneRIF Biological Term Annotations	1.0	null
GSE166004_3_v_6_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
across	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7299-01A-21R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cos-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.296372
TRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49006
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20862
JHH2	CCLE Cell Line Gene CNV Profiles	1.0	2.39988
posttranscriptional	GeneRIF Biological Term Annotations	1.0	null
GSE189683_3_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DLGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18473
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MZT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38439
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
PPP1R15A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33463
Gastrointestinal system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72048
TPBGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26607
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13501
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE112761,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79896
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.539
SRY	ChEA Transcription Factor Targets	1.0	null
MNAT1_Deficiency - Ablation_GDS2561_689_mouse_Heart - 2 week old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5502-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
loaded	GeneRIF Biological Term Annotations	1.0	null
apical plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
LOX-1_OE_GDS4262_434_human_HAECT - aortic endothelial cell line - 12 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
f453	GeneRIF Biological Term Annotations	1.0	null
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
MHH-PREB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Retinoschisis 1, X-Linked, Juvenile	DisGeNET Gene-Disease Associations	1.0	null
vesicle	GO Cellular Component Annotations 2025	1.0	null
hexose transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.567997
GTEX-OXRL-1826-SM-2YUMV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE151612_0_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cystic fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.66
H3-7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36212
GTEX-WQUQ-1326-SM-3MJFF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0461
adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072803
Hypertrophic Obstructive Cardiomyopathy	DisGeNET Gene-Disease Associations	1.0	null
IRAK2_knockout_39_GSE10765	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.24184
Myelencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.012
Acute Myeloid Leukemia_LAML_TCGA-AB-2873-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nitric-oxide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.563
CIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1548
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13396
GSE148692,GSE148695_2_v_4_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE225762_1_v_0_pcmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.68722
Lung squamous cell carcinoma_LUSC_TCGA-22-1017-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4183
ChIP_CHD7_19251738	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BHMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9015
taurine	GeneRIF Biological Term Annotations	1.0	null
GPR176	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64395
496100505_TCx_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0404
TM31	CCLE Cell Line Gene Expression Profiles	-1.0	-2.00688
PMC9942993-pone.0281645.s002.xlsx-AR-as_non-adaptive-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16311
GTEX-WRHU-2826-SM-3MJG8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853806
CL34	CCLE Cell Line Gene Expression Profiles	1.0	1.59397
M059J	GDSC Cell Line Gene Expression Profiles	-1.0	-1.52368
HCC1588	CCLE Cell Line Gene Expression Profiles	1.0	3.40786
BRD-K83952475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92629
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE104022_3_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100658_FWM_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13162
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Brain Lower Grade Glioma_LGG_TCGA-R8-A6MO-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42562
GATA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00458587
Ileum smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
H2AC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25071
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78905
SLC-mediated transmembrane transport	Reactome Pathways 2014	1.0	null
Pneumonia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K47456612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20687
heart_6b	HPA Tissue Sample Gene Expression Profiles	1.0	0.867835
CRCGN015_MCF10A_48H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.048
Cluster of actin-based cell projections	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.46
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.941852
CRCGN015_MCF10A_48H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.17684
GTEX-W5X1-0826-SM-3GILN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06714
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.19
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
containing	GeneRIF Biological Term Annotations	1.0	null
Gut mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.499
MYC-18940864-HL60-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
CIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03749
Ileitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.1562
CANT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66341
GTEX-P4PQ-1526-SM-3NMCK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70565
GTEX-SUCS-0526-SM-4DM56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
biliary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.418861
TRIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48413
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.12185
GTEX-RTLS-2326-SM-46MUH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K21841771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11922
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.412
Rumen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.763
Brain capillary endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.666
membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.003506
AP3D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65996
REDD1_Repression_GDS3558_73_human_Blood Myeloid Cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
r2 part of median raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19945
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.971
GSE209938_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
infants	GeneRIF Biological Term Annotations	1.0	null
RGS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27163
biliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.155418
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11437
Adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930835
exhibits	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5705-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF4	ChEA Transcription Factor Targets	1.0	null
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
HDHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64611
Disease	Reactome Pathways 2024	1.0	null
growth/size/body phenotype	MPO Gene-Phenotype Associations	1.0	null
Malaria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
Prostate adenocarcinoma_PRAD_TCGA-CH-5739-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47988839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37868
Colon adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
PMC10175786-Table4.XLSX-Sheet_1-GSE9750_AND_GSE63514_NOT_GSE7410_NOT_Ferrotosis_genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
postnatal growth retardation	MPO Gene-Phenotype Associations	1.0	null
dapagliflozin	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02874
IMR-5	GDSC Cell Line Gene Expression Profiles	-1.0	-1.56074
Insulin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.195
FAM111A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90827
Perturb_16535_KO_Repin1_SRP108279	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE148695,GSE167284_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LY-294002-318	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE178714_5_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
conserved	GeneRIF Biological Term Annotations	1.0	null
Sodium	HMDB Metabolites of Enzymes	1.0	null
abnormal limb bone morphology	MPO Gene-Phenotype Associations	1.0	null
PMC9942993-pone.0281645.s002.xlsx-AR_as_all_as_maintained-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE100863,GSE100864_3_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Crohn's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.594
Apical plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-T6MN-0926-SM-32PLX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29696
Amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.184
GTEX-PWOO-2226-SM-2S1P1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
transport across blood-brain barrier	GO Biological Process Annotations 2025	1.0	null
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hek293	GeneRIF Biological Term Annotations	1.0	null
GTEX-UPK5-1826-SM-3GAEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.871
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19838
KMS26	CCLE Cell Line Gene CNV Profiles	1.0	2.2263
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830262
ETS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86489
KPNYN	DepMap CRISPR Gene Dependency	1.0	2.00702
trophectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.03961
GRHPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64351
G3BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3421
Food allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
Cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.31
Gastric antrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.888
voltagedependent	GeneRIF Biological Term Annotations	1.0	null
monovalent inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Oral cavity cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
perturbed	GeneRIF Biological Term Annotations	1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.5187
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Median eminence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.978
PMC9376070-41419_2022_5157_MOESM18_ESM.xlsx-Sheet1-Table_S4_Differentially_expressed_genes_of_HNRNPC-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE200352_10_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TUT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04762
Peritoneal dialysis fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
related	GeneRIF Biological Term Annotations	1.0	null
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.177985
EEF1AKMT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.88869
uterine cervix	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089117
NPY5R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35807
MTF2	ChEA Transcription Factor Targets	1.0	null
GTEX-WOFL-0726-SM-3MJG4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
non-Hodgkin lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.114326
LB1047RCC	DepMap CRISPR Gene Dependency	1.0	2.51284
PMC12358249-supplementary_table_s5_ioaf064.xlsx-DMRT1_-_vs_WT__4_months-Unnamed_1_DMRT1	Rummagene Transcription Factor Associations 2026	1.0	null
t66-lung_male_8w	MoTrPAC Rat Endurance Exercise Training	-1.0	-2.90962
endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063013
Lung adenocarcinoma_LUAD_TCGA-95-7947-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE232631_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Early endosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Cardiovascular Diseases	CTD Gene-Disease Associations	1.0	1.72758
GTEX-WY7C-0526-SM-3NB3D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12416
BRD-K32782599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16888
caco-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.518072
GTEX-VUSG-2826-SM-4KKZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
sugar transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.395
RAB22A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07979
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CM-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF284	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96833
BRD-K01452910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03884
transporters	GeneRIF Biological Term Annotations	1.0	null
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
CTDSPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11292
GTEX-UJMC-0526-SM-3GAE3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86199
Bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.076
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63822
SU8686	CCLE Cell Line Gene Expression Profiles	1.0	1.85428
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ATPase dependent transmembrane transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.532
KRT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.319
use	GeneRIF Biological Term Annotations	1.0	null
concentrations	GeneRIF Biological Term Annotations	1.0	null
abnormal body weight	MPO Gene-Phenotype Associations	1.0	null
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
tnfalpha	GeneRIF Biological Term Annotations	1.0	null
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.35763
GTEX-XQ8I-0726-SM-4BOPU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE168604,GSE183859_1_v_0_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
apical part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.304027
17761679-Table1	GeneSigDB Published Gene Signatures	1.0	null
Diabetic neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.375
suboptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.02696
Intestinal absorption	Reactome Pathways 2024	1.0	null
diethylstilbestrol-3812	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-W5WG-1126-SM-4LMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
MDA-MB-157	GDSC Cell Line Gene Expression Profiles	-1.0	-1.76974
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
CACO-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.641
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EJ-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Coronary artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.619
SLC45A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20552
GTEX-SNMC-0226-SM-4DM6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
U-698-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
HMGA2_KO_GSE55340_21_mouse_lung (E18.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
abnormal body size	MPO Gene-Phenotype Associations	1.0	null
BON-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.219
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CDX2_CDX2	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.6349
Capillary endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.171
Muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.37
their	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1678-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2816_KD_SUFU_SRP346101	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.26971
CRCGN017_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19845
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-Q2AG-0926-SM-48U1Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.274045
mRNA_SFPI1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
bridge	GeneRIF Biological Term Annotations	1.0	null
Giardiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
Suprachiasmatic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.903
GSE89729_0_v_1_ppard_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mcf7	GeneRIF Biological Term Annotations	1.0	null
ampk	GeneRIF Biological Term Annotations	1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.546
NLGN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65895
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.9843
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
KLF4-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	3.41751
SNU283	CCLE Cell Line Gene Expression Profiles	1.0	2.04207
plasma membrane part	LOCATE Curated Protein Localization Annotations	1.0	null
Circumventricular organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.336
SCPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32212
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Colon ascendens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.927
extracellular region part	GO Cellular Component Annotations 2015	1.0	null
Cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
RUNX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29435
Mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
GTEX-XV7Q-0726-SM-4BRV6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998177
Renal glycosuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.566
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.91017
FLAD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00572667
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE232631_4_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162276_4_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
into	GeneRIF Biological Term Annotations	1.0	null
Secretory Diarrhea	DisGeNET Gene-Disease Associations	1.0	null
glycosuria	HPO Gene-Disease Associations	1.0	null
TMEM88B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75684
MYLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78605
GTEX-PLZ6-1326-SM-3NB24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-OIZH-1426-SM-3NB1O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18676
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
solute:sodium symporter activity	GO Molecular Function Annotations 2015	1.0	null
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
Glucose-Galactose Malabsorption	CTD Gene-Disease Associations	1.0	2.88009
Salivary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.55
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
r3 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0633
Perturb_11493_OE_Tnfsf15_SRP106312	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.0055
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hemolysis	CTD Gene-Disease Associations	1.0	1.02671
ZNF724	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88536
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1361
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28462
Brush border	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.514
LS180	CCLE Cell Line Gene Expression Profiles	1.0	1.47722
Apical cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.064
Neurohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.03
PLSCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32771
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911934
GSE197630_1_v_0_ruvbl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.16
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4856-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93491540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00489
SC-560-6865	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Left atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.4
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15034
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38892
UT-SCC-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.643
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01831
BRD-K02675272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22022
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
organic substance transport	GO Biological Process Annotations 2015	1.0	null
Microvillus membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.09
GTEX-TKQ1-0526-SM-4DXTG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
UMUC7	DepMap CRISPR Gene Dependency	1.0	2.76271
mRNA_NANOG_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K06308228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01003
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
COMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06122
Lung squamous cell carcinoma_LUSC_TCGA-39-5028-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC-366	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-PK-A5H8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAS	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Abdominal adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.874
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856274
Pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.543
BRD-K66453893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6666
distended cecum	MPO Gene-Phenotype Associations	1.0	null
sodium:potassium-exchanging ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.622
differ	GeneRIF Biological Term Annotations	1.0	null
mapped	GeneRIF Biological Term Annotations	1.0	null
Extracellular space	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.215
HT-29 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.478
GTEX-X62O-1626-SM-46MW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056681
Gut cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.494
Intergeniculate leaflet of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19295
Lung adenocarcinoma_LUAD_TCGA-97-7547-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.703945
BRD-K97242998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.836
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_9_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Glycogen storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
CDK2_knockdown_132_GSE31534	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.24737
NZM42	DepMap CRISPR Gene Dependency	1.0	2.20117
PLPP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13455
Colon cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.576
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.572994
upregulates	GeneRIF Biological Term Annotations	1.0	null
RAB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82526
Renal artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.499
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059022
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01831
SW1116	CCLE Cell Line Gene Expression Profiles	1.0	1.37654
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LGALS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90024
Sox3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8911
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.24213
fucose transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1324	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20037
all	GWASdb SNP-Phenotype Associations	1.0	0.030507
Frond	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
map17	GeneRIF Biological Term Annotations	1.0	null
Allergic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.313
Brain Lower Grade Glioma_LGG_TCGA-DU-5855-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
egfr	GeneRIF Biological Term Annotations	1.0	null
BRD-K83708664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60725
pronounced	GeneRIF Biological Term Annotations	1.0	null
PPP1R1A_KO_GDS1920_708_mouse_hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K99982687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06309
brush border	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.188
GSE158834_0_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
promotes	GeneRIF Biological Term Annotations	1.0	null
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Lung adenocarcinoma_LUAD_TCGA-97-7941-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Type 1 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.139
Congenital glucose-galactose malabsorption	ClinVar Gene-Phenotype Associations 2025	1.0	null
Disorders of transmembrane transporters	Reactome Pathways 2024	1.0	null
Rostral ventrolateral medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
GRIN2B	Pathway Commons Protein-Protein Interactions	1.0	null
Autoimmune disease of musculoskeletal system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
14767473-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
PITPNM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06417
abnormal hormone level	MPO Gene-Phenotype Associations	1.0	null
BRD-K34447537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51989
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.651
hsa-miR-323-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Gastrointestinal allergy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.105
Kidney Chromophobe_KICH_TCGA-KN-8433-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5151-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HIVEP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00592704
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3667
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
skeleton phenotype	MPO Gene-Phenotype Associations	1.0	null
Renal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.765
TMEM41B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77594
slow postnatal weight gain	MPO Gene-Phenotype Associations	1.0	null
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20224
TSC1_Deficiency_GDS4572_347_mouse_Naive CD8 T cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
vascular transport	GO Biological Process Annotations 2025	1.0	null
GTEX-TMZS-0226-SM-3DB9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-XUZC-1626-SM-4BRVP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984077
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19838
BRD-K50443235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6291
Acute Myeloid Leukemia_LAML_TCGA-AB-3006-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.086
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38353
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
disease	GWASdb SNP-Disease Associations	1.0	0.024408
Fanconi-like syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYVS-0326-SM-3NM9V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
hsa-miR-1184	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
Bile duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.589
MITF	ChEA Transcription Factor Targets	1.0	null
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
CRCGN013_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57569
PKM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85478
Prostate adenocarcinoma_PRAD_TCGA-HC-7213-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-6846-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal oral glucose tolerance	HPO Gene-Disease Associations	1.0	null
Venous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.918
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.95178
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43852
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.822
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
PMC8384902-mmc6.xlsx-DEG_ASCL1_3TF_shared-GeneSymbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
SP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.872422
abundance	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-26a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
BRD-K91654198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54932
CRCGN015_MCF10A_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64163
IGR1	CCLE Cell Line Gene CNV Profiles	1.0	1.79275
taken	GeneRIF Biological Term Annotations	1.0	null
HACD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83425
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Duodenal juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary	HPA Tissue Gene Expression Profiles	-1.0	-1.09429
abnormal intestine physiology	MPO Gene-Phenotype Associations	1.0	null
BRD-K47200630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40925
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Exocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.289
Sporulated oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.293
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.01531
Inflammatory bowel disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.003
SCD_KO_GSE24243_46_mouse_Skin (8-9 wk)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC12661646-dmm-18-052290-TableS8.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
sglt2	GeneRIF Biological Term Annotations	1.0	null
19249085-TableE3	GeneSigDB Published Gene Signatures	1.0	null
ASTRA complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.458
PAK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13253
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vii	GeneRIF Biological Term Annotations	1.0	null
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
sodium ion import across plasma membrane	GO Biological Process Annotations 2025	1.0	null
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
intermediate part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15327
tannins	GeneRIF Biological Term Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60386
CHST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46199
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100353_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58237
hsa-miR-3118	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-XUJ4-1126-SM-4BOPC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Bile secretion	KEGG Pathways 2026	1.0	null
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.75603
Female reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.325
layer 1 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18263
PCYOX1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83569
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.774834
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.2288
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.49
Goblet cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.99
medial part of r3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05033
Renal Insufficiency	DisGeNET Gene-Disease Associations	1.0	null
Carotid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
PMC11833364-tcr-14-01-340-supplementary.pdf-59-ZSCAN18_ZSCAN18	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K49507197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84297
GSE148200_0_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03299
BRD-K89108431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.58514
BRD-K32913479	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14196
HCC1599	GDSC Cell Line Gene Expression Profiles	1.0	1.67364
Kidney renal clear cell carcinoma_KIRC_TCGA-EU-5907-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5745-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37253893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8727
BRD-K30220159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39255
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02416
hsa-miR-1301	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
GSE146074_1_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.478
Medullary reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28023
against	GeneRIF Biological Term Annotations	1.0	null
BRD-A44990218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04755
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Sheet3-The_overlapping_genes_between_significantly_co-expressed_genes_and_significantly_differentially_expressed_genes_of_BARX2_in_LIHC_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
duodenum_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.73942
RCC4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86205
HIVEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93835
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4946
dilazep-3665	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-3978	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44632
r10 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.73635
hsa-miR-4276	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K74245698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49358
directly	GeneRIF Biological Term Annotations	1.0	null
intestinal absorption	GO Biological Process Annotations 2015	1.0	null
PXK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0062647
Polycystic ovary syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
RNF125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14727
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.061
GTEX-NFK9-1326-SM-3LK5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
PITPNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79533
GTEX-SNOS-0326-SM-4DM6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K29713418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31017
GTEX-R53T-0826-SM-48FCP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A736-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K50092006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31435
Atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.499
amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.075588
mRNA_SOX2_17515932	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2969-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K06719105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44859
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVMANA	DepMap CRISPR Gene Dependency	1.0	2.46881
GSE129186,GSE129223_0_v_1_aicda_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Fatty acid synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.212
PMC12661646-dmm-18-052290-TableS6.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
Cardiac microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.103
GTEX-RVPU-2326-SM-2TF6R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
NCIH1869	CCLE Cell Line Gene CNV Profiles	1.0	1.67668
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061384
BRD-K49051633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01406
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
Cortical collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.348
GSE127790_9_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.71925
Neoplasms	CTD Gene-Disease Associations	1.0	1.8836
TBX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29233
CRCGN014_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0028
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S05_LF_C2_3h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.57066
Renal fibrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.624
CD83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7158
ondansetron-6153	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tumors	GeneRIF Biological Term Annotations	1.0	null
Na+-dependent glucose transporters	Reactome Pathways 2014	1.0	null
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
SECISBP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48157
CRCGN013_HEPG2_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08569
shock	GeneRIF Biological Term Annotations	1.0	null
GTEX-S4P3-0926-SM-4AD54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
pregeniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34855
CRCGN011_HEPG2_24H:N10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12025
MRFAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94586
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Inositol transporters	Reactome Pathways 2014	1.0	null
TCF3-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.712
UNC93B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0050073
Kidney hypertrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.418
GTEX-P78B-0226-SM-3NB1Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
SLC-mediated transmembrane transport	Reactome Pathways 2024	1.0	null
BRD-K41719231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86206
BRD-K34004579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6766
SOTAGLIFLOZIN	DGIdb Drug Targets 2026	1.0	4.15153
GSE200673,GSE200691_2_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.261
GSE124048,GSE124067_1_v_0_irf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K52735829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16774
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.11863
Mesenteric adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.844
Nuclear receptors meta pathway	WikiPathways Pathways 2024	1.0	null
GTEX-U3ZH-0326-SM-3DB7A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42705
identifying	GeneRIF Biological Term Annotations	1.0	null
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57552
RDH11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0055084
GTEX-VUSG-0626-SM-4KL1Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30498
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.935525
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.3085
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.9838
PRKCI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86037
Calcium	CTD Gene-Chemical Interactions	1.0	null
EZH2-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
liminal part of the r9 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22973
staurosporine-425	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COVID-19	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.439
imatinib_homo sapiens_gpl96_gds3048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K17441474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00097
AGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53959
SCID - Severe combined immunodeficiency_Lung Tissue_GSE3414	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.16884
Disease	Reactome Pathways 2014	1.0	null
Caki-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
BRD-K46588240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71035
GSE82032_3_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.57971
Enteric nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.688
BRD-K81200901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6295
abnormality of body weight	HPO Gene-Disease Associations	1.0	null
TCEAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58548
Submandibular gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.102
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47642
Eating disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
especially	GeneRIF Biological Term Annotations	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.111
BRD-K11757577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1182
Viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.083
ChIP_SUZ12_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Area postrema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.314
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10544
growth abnormality	HPO Gene-Disease Associations	1.0	null
BRD-K47776393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84737
dehydration	HPO Gene-Disease Associations	1.0	null
GSE205550,GSE205552_2_v_3_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAB6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93003
RUNX1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Lipid metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.14
Endosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Prostate adenocarcinoma_PRAD_TCGA-CH-5791-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112765,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GTEX-V955-0126-SM-4JBH5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
diphenylpyraline-6061	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PLZ6-1526-SM-2S1OC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.63631
measurements	GeneRIF Biological Term Annotations	1.0	null
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
sisomicin-4014	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Aorta thoracica	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.95
irinotecan_rattus norvegicus_gpl1355_jejunum_gds3466	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K00048155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47453
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49056
GTEX-XGQ4-1626-SM-4AT6J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Cluster of actin-based cell projections	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
POLR2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96443
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164874_5_v_1_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SJXC-0126-SM-2XCFF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930637
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KNS81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35037
model	GeneRIF Biological Term Annotations	1.0	null
GTEX-XBEC-1226-SM-4AT65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08676
DPY-21335234-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Ovarian cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
GSE96641_1_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QV44-0826-SM-2S1RG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Sieve tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21051
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45O-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
younger	GeneRIF Biological Term Annotations	1.0	null
ZNF568	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60321
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87508
BRD-K10181552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48702
Superior mesenteric vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
CRCGN017_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54581
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069869
Carbohydrate digestion and absorption	KEGG Pathways 2026	1.0	null
BRD-K85161353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32067
Pneumonitis	DisGeNET Gene-Disease Associations	1.0	null
monosaccharide transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
Epididymis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.342
PDZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19298
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.2437
hexose	GeneRIF Biological Term Annotations	1.0	null
transgolgi	GeneRIF Biological Term Annotations	1.0	null
adrenal gland	HPA Tissue Gene Expression Profiles	-1.0	-1.38422
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05463
PAR polarity complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.697
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SUZ12-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38908
SUZ12-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.229
chronic diarrhea	HPO Gene-Disease Associations	1.0	null
Hypertension	CTD Gene-Disease Associations	1.0	1.92595
ERTUGLIFLOZIN	DGIdb Drug Targets 2026	1.0	1.03788
KAP1-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Chorioallantois	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE150	DepMap CRISPR Gene Dependency	1.0	6.29683
hsa-miR-4329	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
Colorectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.43
Pronephric tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.12
Integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.86
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.860854
zygote	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.139203
monosaccharide transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
HCC33	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82666
Parasitic protozoa infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.56
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Gonadal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.459
Perturb_9766_KO_Shp2_SRP285005	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	19.0
smallintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
GTEX-OXRO-1926-SM-2S1O3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
brush border membrane	GO Cellular Component Annotations 2023	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28318
OE19	CCLE Cell Line Gene Expression Profiles	1.0	1.67568
BRD-K81544427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15733
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.899
Plasma membrane region	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.89
abnormal renal reabsorbtion	MPO Gene-Phenotype Associations	1.0	null
Urinary tract obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.202
protects	GeneRIF Biological Term Annotations	1.0	null
PODXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94225
Kidney Tubular Necrosis, Acute	CTD Gene-Disease Associations	1.0	1.25121
Kidney Failure, Acute	DisGeNET Gene-Disease Associations	1.0	null
SALL4-18804426_ESC-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
d11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.883
endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089079
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	1.69499
Artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.141
long femur	MGI Mouse Phenotype Associations 2023	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.67175
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.52052
Brain Lower Grade Glioma_LGG_TCGA-DU-7306-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216238,GSE216241_0_v_1_tonsl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20196153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04408
Epitrochlearis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.04
PDK1_knockout_80_GSE26290	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.8591
LRIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90835
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Gynoecium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.432
GSE248858_6_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120336_1_v_2_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K08647020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63781
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148692,GSE148695_7_v_4_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TTI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3255
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.641
GTEX-S4Z8-0926-SM-4AD6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Glioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
alpha-glucoside transport	GO Biological Process Annotations 2023	1.0	null
BRD-K12097074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02267
LMAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8547
SERPINB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89918
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84509
Exoskeleton	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	1.0	1.50699
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.971
r3 pontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04487
COLO849	CCLE Cell Line Gene CNV Profiles	1.0	1.6866
PMC11378415-12943_2024_2100_MOESM6_ESM.xlsx-CopyNumberGain_ExpDown-GRHL1_GRHL1	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03845
placenta_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38407
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	1.0	1.79727
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06873
CHD7	ChEA Transcription Factor Targets	1.0	null
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.85551
GTEX-S32W-0626-SM-2XCBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77829
Hepatopancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.847
AOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0174
congenital	GeneRIF Biological Term Annotations	1.0	null
SLC3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98643
ZNF639	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01076
monosaccharide transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE148066,GSE157787_9_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_18392_KO_923large_SRP286259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.39443
GSE135514_8_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Polyketide synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.954
NCI-H1876	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mantle zone of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05252
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
hsa-miR-1297	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3373-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE193177_1_v_2_st266_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65944
ZNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47909
protecting	GeneRIF Biological Term Annotations	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.74834
Renal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.658
CLCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55075
suggests	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-0826-SM-3NMBF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55331
Perturb_9658_KD_SKIDA1_SRP306591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
should	GeneRIF Biological Term Annotations	1.0	null
periventricular stratum of Pal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91758
Cardiomyopathies	CTD Gene-Disease Associations	1.0	1.28027
EPM2AIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19005
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DLAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04089
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91931
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-QEG4-0426-SM-33HC3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35125
Cystinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.743
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.11199
dynamindependent	GeneRIF Biological Term Annotations	1.0	null
medial amygdala, posterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06911
GSE211955_1_v_0_jmjd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K33287655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02668
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7979
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4976-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Peritoneal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.817
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
PCM6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51631
GSE190947_1_v_0_xbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
therefore	GeneRIF Biological Term Annotations	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.184
SALL4-18804426-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZIC3	ChEA Transcription Factor Targets	1.0	null
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851187
Podocyte foot	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.655
Starch grain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.125
STT3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85154
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
jejunum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.963335
SARS-CoV MA15_Day4-PFU-10^4_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.82064
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26485
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.744
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45872
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02193
Viral RNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.562
BRD-K42138859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60418
Hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.915
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GLP-1 levels in response to oral glucose tolerance test (120 minutes)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
GSE183251_4_v_6_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intracellular	GeneRIF Biological Term Annotations	1.0	null
GTEX-XGQ4-1326-SM-4GIDU	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22824
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.838923
established	GeneRIF Biological Term Annotations	1.0	null
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889956
MM1S	DepMap CRISPR Gene Dependency	1.0	3.48606
RBAK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67965
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE206093,GSE206094_1_v_3_isl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLEKHG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06449
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.889019
Brain Lower Grade Glioma_LGG_TCGA-DU-6393-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fruit juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.729
ZBTB43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74757
major	GeneRIF Biological Term Annotations	1.0	null
16143142-Table3	GeneSigDB Published Gene Signatures	1.0	null
BCL2L12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30589
BRD-K91094364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61045
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mesentery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.142
GTEX-P4PP-0426-SM-3NM9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K12984952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08055
lateral tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00408
Insulinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6220-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SFSWAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43299
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.21924
Intestinal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.171
GRINA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52737
GTEX-V955-0426-SM-3GAEL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
INPP4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35425
hsa-miR-1285	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7233
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
SLC39A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42142
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21331
BRD-K39348592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01412
AP1G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55878
sbc2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
BRD-K78643409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15883
Trophectoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.075
symporter activity	GO Molecular Function Annotations 2015	1.0	null
monosaccharide transmembrane transport	GO Biological Process Annotations 2025	1.0	null
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31511
BRD-K37253987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21399
GSE206870,GSE206872_3_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Arteriole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.991
blastula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.416576
Tubulointerstitium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.752
Ileal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.952
other	GeneRIF Biological Term Annotations	1.0	null
CHD7-19251738-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
any	GeneRIF Biological Term Annotations	1.0	null
mantle zone of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33289
BRD-K52570793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05897
REST_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
shortterm	GeneRIF Biological Term Annotations	1.0	null
Osteolysis_Leukocyte - Lymphocyte - B-Lymphocyte - Plasma Cell (MMHCC)_GSE755	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.79949
BEXAGLIFLOZIN	DGIdb Drug Targets 2026	1.0	1.55682
SMARCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.07451
abnormal body composition	MPO Gene-Phenotype Associations	1.0	null
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S33H-0008-SM-4AD6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33089
KYSE-140	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Globus pallidus, external segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41915
KCNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93312
naglucose	GeneRIF Biological Term Annotations	1.0	null
PMC10714175-mmc2.xlsx-KD_Gene_list-Supplemental_Table_3_FAM13B_knockdown_mediated_changes_in_gene_expression_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I5-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE138019_1_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K92479346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14789
PMC10778733__F3	PFOCR Pathway Figure Associations 2024	1.0	null
ChIP_GCN5_20946988	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
septic	GeneRIF Biological Term Annotations	1.0	null
abnormal small intestine morphology	MGI Mouse Phenotype Associations 2023	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.485156
Parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.585
different	GeneRIF Biological Term Annotations	1.0	null
GTEX-XXEK-1026-SM-4BRUW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.72651
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K17790291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64761
TOV112D	DepMap CRISPR Gene Dependency	1.0	2.76391
Capillary	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.02
hsa-miR-3928	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Prestwick-689-6076	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
19658189-TableS8d	GeneSigDB Published Gene Signatures	1.0	null
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05252
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.32392
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A74V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Microvillus inclusion disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.099
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.914292
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19562
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51046
GTEX-P4QT-2626-SM-2I3FM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
CSNK1A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00626
ZDHHC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73355
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.446
IGHMBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92427
GTEX-U3ZH-0426-SM-4DXSE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
ventral subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26585
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040545
Tepal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.597
Necrosis	CTD Gene-Disease Associations	1.0	2.18542
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83735
BRD-K46742113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83668
SHFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60002
DPYSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61494
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29128
turnover	GeneRIF Biological Term Annotations	1.0	null
GTEX-PLZ6-0926-SM-3P5ZQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886483
BRD-K30310320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66247
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10034
phlorizin	GeneRIF Biological Term Annotations	1.0	null
MED14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73641
CEP350	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95702
KYSE-510	GDSC Cell Line Gene Expression Profiles	-1.0	-1.49152
Dermatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
Cortical actin cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.231
Autonomic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.972
Urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.858
ATAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44099
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85808
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.38
T3M10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52927
heart	GTEx Tissue Gene Expression Profiles	1.0	1.01162
Biliary tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
STAT5-23275557-MAMMARY-EPITHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perinatal necrotizing enterocolitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.405
trophoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.503926
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Chloride channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.415
hsa-miR-4717-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13396
RPL22L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77984
GTEX-OXRK-0826-SM-2HMK7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57919
Capsular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.637
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K08730943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22786
TYKNU	DepMap CRISPR Gene Dependency	1.0	2.05979
SNU119	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66655
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76529
ZNF507	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59557
caco2	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72849
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PYCR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01503
CYB561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84918
HSPA1B	Pathway Commons Protein-Protein Interactions	1.0	null
Superior mesenteric artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.087
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059754
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Enterocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.119
BRD-K63462027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03608
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02822
tear gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.361155
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47384
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.64416
Small_Intestine-paneth cell of epithelium of small intestine	Tabula Sapiens Gene-Cell Associations	1.0	1.1568
FGD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32226
NCIH2342	CCLE Cell Line Gene CNV Profiles	1.0	1.47538
Prostate adenocarcinoma_PRAD_TCGA-CH-5790-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94088431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68657
Brush cell (Tuft cell)_Intestinal crypt_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
carboxyl	GeneRIF Biological Term Annotations	1.0	null
kinetic	GeneRIF Biological Term Annotations	1.0	null
BRD-K44212150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05399
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.617
DRAXIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67487
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.2
duodenum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.632335
abnormal glucose homeostasis	HPO Gene-Disease Associations	1.0	null
Lactic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.666
GSE205550,GSE205552_2_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CDK5RAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78478
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-1726-SM-2S1NS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
ACTN2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K62188824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29577
GTEX-T5JC-0226-SM-32PMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4A-Supplemental_Table_S4A_Differentially_expressed_genes_upon_ZFX_Knock_down_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
OVOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26763
hsa-miR-485-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
Hyperparathyroidism, Secondary	HuGE Navigator Gene-Phenotype Associations	1.0	null
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25794
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85629
hsa-miR-3658	TargetScan Predicted Conserved microRNA Targets	1.0	0.065994
Perturb_18149_KO_Ikbkb/Shp2_SRP285005	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.07906
abnormal digestive system physiology	MPO Gene-Phenotype Associations	1.0	null
mantle zone of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88319
layer II of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00426
Perturb_11332_KO_Dicer_SRP041679	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
CAMK2D	Pathway Commons Protein-Protein Interactions	1.0	null
Ureteral disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
Diabetic retinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.621
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.922055
increased urine glucose level	MPO Gene-Phenotype Associations	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81597
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
cyclobenzaprine-4834	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
site	GeneRIF Biological Term Annotations	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	1.0	1.37624
metal ion transport	GO Biological Process Annotations 2015	1.0	null
Peroxisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.794
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12089436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47934
cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064103
Sepsis	DisGeNET Gene-Disease Associations	1.0	null
OSC20	DepMap CRISPR Gene Dependency	1.0	3.0832
Viral infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.647
Myenteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.424
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.863891
Congenital lactase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.125
organ development	GO Biological Process Annotations 2015	1.0	null
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
kidney development	GO Biological Process Annotations 2015	1.0	null
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0329
Antral mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
BRD-K54834493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05794
Uterine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44613
BRD-A56345662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10152
TMEM190	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31277
mRNA_NANOG_16767105	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
abnormal limb long bone morphology	MPO Gene-Phenotype Associations	1.0	null
perinatal necrotizing enterocolitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.440914
BRD-K85275903	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23169
CRCGN017_MCF10A.TP53.M_24H:E08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12891
first	GeneRIF Biological Term Annotations	1.0	null
Bursa of Fabricius	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.958
CRCGN012_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3822
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.156
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE152937_12_v_7_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K80851151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03438
BRD-A77181042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00063
Atrial fibrillation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.79
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.981096
Anus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43038
PMC12451251-BMRI-2025-9283631-s001.xlsx-Target-STAT3_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of THyB-I	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.36518
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.536
CENPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29852
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
native	GeneRIF Biological Term Annotations	1.0	null
cell projection part	GO Cellular Component Annotations 2015	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.862627
Constipation - Functional	DisGeNET Gene-Disease Associations	1.0	null
pl92	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.729
ZNF695	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67286
GSE152937_12_v_1_slc16a13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Apical junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.116
epithelium	GeneRIF Biological Term Annotations	1.0	null
lateral part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4145
DDX25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74553
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.26092
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Pinealocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.898692
sodium ion transport	GO Biological Process Annotations 2015	1.0	null
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Latent autoimmune diabetes in adults	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
ZBTB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53074
OE19	GDSC Cell Line Gene Expression Profiles	1.0	1.56381
enterocytes	GeneRIF Biological Term Annotations	1.0	null
colonic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.319498
Intestinal infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.543
cell part	GO Cellular Component Annotations 2015	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.49079
Adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.243
Anchoring junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.35
BRD-K40988761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3623
C99	DepMap CRISPR Gene Dependency	1.0	2.24207
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
AMZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23319
CRCGN015_MCF10A.TP53.M_24H:J24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21615
GSE181517_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Medial geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08243
GTEX-S4UY-0826-SM-4AD4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915544
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
lateral part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33289
morula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.149535
r2 part of prepontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17661
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.970005
triglyceride-rich plasma lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.616
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930349
Mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.672
current	GeneRIF Biological Term Annotations	1.0	null
SH3BP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26681
GSE164884_2_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
I-cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.033
TFAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32401
OGFOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56392
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0584
reserpine-3003	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.869084
Honey	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.392
upregulation	GeneRIF Biological Term Annotations	1.0	null
inner CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861247
Calcitonin family receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.998
PMC10773028-40364_2023_552_MOESM1_ESM.xlsx-Variants_sheet-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_108_KO_SATB2_SRP307577	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.98657
amediated	GeneRIF Biological Term Annotations	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
DPY19L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22615
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
FGF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45021
ZNF384	ENCODE Transcription Factor Targets	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19838
reduced	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4660	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
Liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.446
KYAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96098
BRD-K73706189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19043
Perturb_6689_KD_LAD1_SRP117048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.0266
GSE73628_8_v_2_igf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55374
HSC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
sglt	GeneRIF Biological Term Annotations	1.0	null
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-QLQ7-0526-SM-2I5G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84482
propylthiouracil-4157	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X3Y1-0226-SM-3P5Z5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3011
YAP1	ChEA Transcription Factor Targets	1.0	null
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5035
RUNX2_NULL MUTATION_GDS2184_719_mouse_Embryonal bone (MG-U74A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC5977767__F6	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907648
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
RFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37717
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-XBED-0526-SM-47JY3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75192
NEFL	Pathway Commons Protein-Protein Interactions	1.0	null
CAMLG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83653
GTEX-P4QT-2426-SM-3NMCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
RBCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01482
A427	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16079
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.964873
GTEX-REY6-1426-SM-48FDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
MDAMB453	CCLE Cell Line Gene CNV Profiles	1.0	1.3679
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.828523
Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.729684
BRD-K19969409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24115
r9 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63502
Lung squamous cell carcinoma_LUSC_TCGA-37-3789-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V955-2526-SM-4JBJG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.43953
renal glycosuria	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.12572
Osmotic diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.453
Gizzard	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.291
glucose transport	GO Biological Process Annotations 2015	1.0	null
conformations	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7372-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.53312
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.943421
PXR (PXR:RXR)	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-XMK1-1726-SM-4B64Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996648
Middle Cerebral Artery Occlusion	DisGeNET Gene-Disease Associations	1.0	null
galactose:sodium symporter activity	GO Molecular Function Annotations 2023	1.0	null
renal proximal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.862627
Oocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.426
GTEX-NPJ8-0226-SM-48TBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831796
BRD-K97226655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42982
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.59
localization	GeneRIF Biological Term Annotations	1.0	null
enterocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.849585
hsa-miR-4650-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Impaired Glucose Tolerance	DisGeNET Gene-Phenotype Associations	1.0	null
myo-inositol transport	GO Biological Process Annotations 2025	1.0	null
MRPS34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54552
Thorax muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.249
BRD-K20073772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92931
inorganic cation import across plasma membrane	GO Biological Process Annotations 2023	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5181-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DYNC1LI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8316
CCDC117	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65535
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE94011_2_v_1_pias3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_11089_Mut_Tak1/Ripk1_SRP256942	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.98304
Urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.866
ZNF44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79497
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:K12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08095
GALR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85553
l6.c11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.596
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.869373
BRD-K75094875	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33646
SNU1079	DepMap CRISPR Gene Dependency	1.0	2.01068
copper sulfate-438	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.97731
vesicle	GO Cellular Component Annotations 2015	1.0	null
Feather vane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.548
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87245
CAV3_KO_GDS3533_357_mouse_mammalian glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K03608799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23429
IKBKE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47456
BRD-K38345640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80106
PDIA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4079
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.4388
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
IgA glomerulonephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
Rectum adenocarcinoma_READ_TCGA-DY-A1DE-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RMI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28648
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ASH2L-23239880-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062403
work	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4682	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Duodenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.702
BRD-K84073439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1149
GSE253799_0_v_1_matn3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15942
Lung adenocarcinoma_LUAD_TCGA-86-7701-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Triple Negative Breast Neoplasms	DisGeNET Gene-Disease Associations	1.0	null
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03381
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7733
metanephros development	GO Biological Process Annotations 2015	1.0	null
GTEX-S4Q7-0326-SM-3K2B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4043
GSE200673,GSE200691_1_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3942-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.111118
BRD-K59957885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1885
Cholera	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.609
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08497
GTEX-WL46-0926-SM-3LK7T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03663
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ovarian	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09488
inorganic anion transmembrane transport	GO Biological Process Annotations 2023	1.0	null
Familial hyperlipidemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
IFT57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11949
examined	GeneRIF Biological Term Annotations	1.0	null
BRD-A52377240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96882
CLDN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25381
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11381
CRCGN016_MCF10A.TP53.M_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12675
Gas bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
CRCGN011_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2932
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
ZNF493	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25557
CORL279	CCLE Cell Line Gene Expression Profiles	-1.0	-1.82719
Renal carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
Ec	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.128
BRD-K90157100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09454
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
SLC15A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22544
GSE112761,GSE112767_4_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
bed nucleus of the stria terminalis, mediocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24536
fp95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.745
Mucous cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.979
f96	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
occluded	GeneRIF Biological Term Annotations	1.0	null
BRD-A24714998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2853
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5503
NCI-H2009	GDSC Cell Line Gene Expression Profiles	1.0	1.66603
BRD-K71647210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43084
GUK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65334
inner SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33801
GSE96641_5_v_0_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMK1-1126-SM-4IHJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
UBE2J2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47384
t70-white-adipose_female_4w	MoTrPAC Rat Endurance Exercise Training	1.0	2.29974
BRD-A69110666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11054
Sarcoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.977
including	GeneRIF Biological Term Annotations	1.0	null
GSE213650_0_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K91962463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39341
Renal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5844-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5K3-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Parotid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.078
BRD-K77082178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46495
NANOG-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
RAP2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8752
GTEX-X8HC-2726-SM-46MUA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Perturb_4484_OE_Msi2_SRP067535	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.33534
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.951168
Perturb_9255_KO_Cftr_SRP067491	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.5836
CAL72	DepMap CRISPR Gene Dependency	1.0	3.80264
Pulp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.985
HDAC2	ENCODE Transcription Factor Targets	1.0	null
p53	GeneRIF Biological Term Annotations	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
PMC9046280-41467_2022_29963_MOESM5_ESM.xlsx-ASCL1_motif-Gene_Name_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
DLX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24545
RPL39L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75658
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
extracellular vesicular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
serum	GeneRIF Biological Term Annotations	1.0	null
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236502_1_v_3_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5481429-41598_2017_4370_MOESM2_ESM.xls-SOM-cluster-genes_transcriptionally_related_to_DNAJC22_in_human_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04043
Gastroduodenal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
distended cecum	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Pancreatic colloid cystadenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
abnormal bone structure	MPO Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4903-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164494_0_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane part	LOCATE Curated Protein Localization Annotations	1.0	null
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TPGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66848
biomarker	GeneRIF Biological Term Annotations	1.0	null
Glucose	CTD Gene-Chemical Interactions	1.0	null
monovalent	GeneRIF Biological Term Annotations	1.0	null
ST6GALNAC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05547
D-glucose import across plasma membrane	GO Biological Process Annotations 2025	1.0	null
Golgi membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.248
nicotine_mus musculus_gpl1261_gse31004	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K82102352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00929
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2626
1,5-anhydroglucitol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.22218
TAF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.354
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.3682
Brain Lower Grade Glioma_LGG_TCGA-DU-A76R-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144443_5_v_3_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01063
ZFP37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52837
Gastric fundus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.739
Perturb_3833_KO_Satb2_SRP307575	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.46657
backbone	GeneRIF Biological Term Annotations	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13501
t70-white-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	6.89903
BRD-K27971671	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32847
D-glucose:sodium symporter activity	GO Molecular Function Annotations 2025	1.0	null
Caco-2/15 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.711
inflammatory	GeneRIF Biological Term Annotations	1.0	null
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.37903
corresponding	GeneRIF Biological Term Annotations	1.0	null
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85909950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2844
POLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13471
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
small intestine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.200916
vesicle	GO Cellular Component Annotations 2023	1.0	null
early endosome	GO Cellular Component Annotations 2025	1.0	null
treatments	GeneRIF Biological Term Annotations	1.0	null
BRD-K33865795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07339
medial geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20286
Urinary bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.969
MRPS14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06378
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8564-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
basis	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4325-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM187	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8381
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6MF-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
downregulated	GeneRIF Biological Term Annotations	1.0	null
496100522_PCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07611
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28983
J82	DepMap CRISPR Gene Dependency	1.0	4.23186
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
renal tubular transport disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.295851
PRDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15243
CAL33	DepMap CRISPR Gene Dependency	1.0	2.62994
Perturb_16533_KO_Cdk8_SRP351257	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
developmental process	GO Biological Process Annotations 2015	1.0	null
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	1.0	null
chlorcyclizine-6053	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K39267096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22891
abnormal cecum morphology	MPO Gene-Phenotype Associations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.928215
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.542
CD2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90697
brush border membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
mRNA_FEM1B_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Jejunal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.509
Urinary bladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.306
position	GeneRIF Biological Term Annotations	1.0	null
hexose transport	GO Biological Process Annotations 2015	1.0	null
Cervix disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12522
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE232631_4_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Pyelonephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.568
LACTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29081
TPBG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59531
packing	GeneRIF Biological Term Annotations	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Pyelitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
NAMALWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
support	GeneRIF Biological Term Annotations	1.0	null
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.126237
SLC4A1AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99603
access	GeneRIF Biological Term Annotations	1.0	null
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.275
MSTO-211H	GDSC Cell Line Gene Expression Profiles	-1.0	-2.20192
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5004-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NOTCH_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
BRD-A63342325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73314
BRD-K37515001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26271
BRD-K82401173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09498
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.513
GTEX-S4Q7-0226-SM-4AD5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
COPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26226
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-A6W5-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
nadolol-4139	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
highcapacity	GeneRIF Biological Term Annotations	1.0	null
TP53I3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10307
glucose	GeneRIF Biological Term Annotations	1.0	null
GSE230744,GSE237803_0_v_3_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-1245b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
Liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.503
CGN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36184
abnormal glucose tolerance	HPO Gene-Disease Associations	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8143-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08243
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GRIN2C	Pathway Commons Protein-Protein Interactions	1.0	null
Renal tubular acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
RAB3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03779
GSE112761,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7165319-3896263.f6.xlsx-List_of_significantly_diffenent-Significantly_different_proteins_between_AA_pool_and_CON_pool_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
D-glucose transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
abnormal total tissue mass	MPO Gene-Phenotype Associations	1.0	null
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
inhibitory	GeneRIF Biological Term Annotations	1.0	null
Terminal loop	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.08
GTEX-XPVG-1526-SM-4B66C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
SW620	DepMap CRISPR Gene Dependency	1.0	2.37604
MOB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44572
mantle zone of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43257
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.49077
ISG15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9801
GSE255432_6_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
aortic endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.185221
rectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.14165
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.76269
Bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.048
PMC4013402__F1	PFOCR Pathway Figure Associations 2024	1.0	null
Epiglottis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
ZNF280C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16951
alteration	GeneRIF Biological Term Annotations	1.0	null
GSE210885_5_v_6_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Berry	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.961
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Glycosuria	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0368
GTEX-SNMC-1626-SM-4DM52	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-UJMC-1326-SM-4IHLS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955723
salivary gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219707
vesicles	GeneRIF Biological Term Annotations	1.0	null
BICD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95359
Perturb_13243_KD_Lnc956_SRP345092	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
duodenum	HPA Tissue Gene Expression Profiles	1.0	1.56884
nedd42	GeneRIF Biological Term Annotations	1.0	null
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.149
central amygdaloid nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7624
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Supplementary_Table_2E_Contrast_ATF4-def_Tg_8h_vs_HCT116_Tg_8h_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-2W-A8YY-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.804
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blastomere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.145966
Uterine horn	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.783
IGSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96707
superficial stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03398
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-8254-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
schizophrenia	GWASdb SNP-Phenotype Associations	1.0	0.57836
TBC1D25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76973
496100523_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.215
Peritoneal mesothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
carbonyl	GeneRIF Biological Term Annotations	1.0	null
Asthma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
Dysentery	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.468
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.76534
Glomerulonephritis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K39013648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19766
GSE115542_5_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NEK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00470658
Metabolism	Reactome Pathways 2014	1.0	null
Gall bladder epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.37624
GSE193282_3_v_1_cd44_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
t99-vena-cava_male_4w	MoTrPAC Rat Endurance Exercise Training	1.0	1.37313
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
abnormal hindlimb stylopod morphology	MPO Gene-Phenotype Associations	1.0	null
decreased circulating glucose level	MGI Mouse Phenotype Associations 2023	1.0	null
BICR10	DepMap CRISPR Gene Dependency	1.0	2.49516
Mucilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
Perturb_11474_OE_SOX9_SRP341040	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.0739
described	GeneRIF Biological Term Annotations	1.0	null
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE70883,GSE71179_0_v_1_pbx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
apple	GeneRIF Biological Term Annotations	1.0	null
Hyperuricemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.698
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48124
leading	GeneRIF Biological Term Annotations	1.0	null
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.992
Gastric gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.165
seems	GeneRIF Biological Term Annotations	1.0	null
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
Coronavirus infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.444
Balanitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.954
Infertility, Male	CTD Gene-Disease Associations	1.0	1.41368
cervical cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.242054
primary motor cortex (area M1, area 4)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.87342
surface	GeneRIF Biological Term Annotations	1.0	null
Congestive heart failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.702
PMC4695334-mmc3.xls-HCC_SMAD3_DNA_Me-HCC-unique_genes_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K81281620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59614
PANK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83858
inhibitors	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-513b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
DIPK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9295
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
hutu80	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.31613
BRD-K27599706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64421
HUH6	DepMap CRISPR Gene Dependency	1.0	4.30509
PMC7923230__F6	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K53326976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83055
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
ENAVOGLIFLOZIN	DGIdb Drug Targets 2026	1.0	1.55682
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-6690-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain microvascular endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.805
abnormal trabecular bone morphology	MPO Gene-Phenotype Associations	1.0	null
Rectum adenocarcinoma_READ_TCGA-F5-6813-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53942
Fasciitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
intestinal D-glucose absorption	GO Biological Process Annotations 2025	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DENND10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95531
chain	GeneRIF Biological Term Annotations	1.0	null
Clove	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18813
GTEX-RTLS-0826-SM-2TF5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12797
Hemoglobin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.403
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E1-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal postnatal growth/weight/body size	MPO Gene-Phenotype Associations	1.0	null
inorganic anion transmembrane transport	GO Biological Process Annotations 2025	1.0	null
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14459
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NEK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93589
CRCGN015_HEPG2_48H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16382
periventricular stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26428
HCC38	DepMap CRISPR Gene Dependency	1.0	3.63687
GTEX-TKQ2-0226-SM-4DM6V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.928215
Sarcoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.475
Congenital Glucose-Galactose Malabsorption	DisGeNET Gene-Disease Associations	1.0	null
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.298371
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K51278788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39092
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042665
Lung squamous cell carcinoma_LUSC_TCGA-37-4141-01A-02R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8049-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver Cirrhosis, Experimental	CTD Gene-Disease Associations	1.0	1.09262
BLZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5888
GTEX-O5YW-0426-SM-3MJHJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
myenteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217139
BRD-K34343777	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64398
brush border membrane	GO Cellular Component Annotations 2025	1.0	null
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06414
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054842
had	GeneRIF Biological Term Annotations	1.0	null
GTEX-O5YV-0226-SM-48TBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Perturb_11492_OE_Tnfsf15_SRP106312	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.9143
PMC12703266-gutjnl-75-1-s002.pdf-29-HES6_HES6	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4672	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825165
Brain Lower Grade Glioma_LGG_TCGA-DU-A7T6-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TC138	DepMap CRISPR Gene Dependency	1.0	2.68829
GTEX-XQ3S-1326-SM-4BOPQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Intestinal hexose absorption	Reactome Pathways 2024	1.0	null
19249085-Table4	GeneSigDB Published Gene Signatures	1.0	null
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.059
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10545357-medi-102-e35220-s002.xlsx-intersection_targets-NR3C2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF512	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86881
NCI-H1648	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SARS-CoV MA15_Day7-PFU-10^5_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.55899
MGAT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65239
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K80414383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51055
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
NANOG-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CGB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02565
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
abnormal large intestine morphology	MPO Gene-Phenotype Associations	1.0	null
Caco-2/BBe cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.119
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-1126-SM-48TZ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.299
patient	GeneRIF Biological Term Annotations	1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_MYOD1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pleated septate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.863
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Neonatal diabetes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
White adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.06
Fructose	CTD Gene-Chemical Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6790-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.687
Hypoglycemia	DisGeNET Gene-Disease Associations	1.0	null
GSE173873_2_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Renal parenchyma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.007
Lung adenocarcinoma_LUAD_TCGA-55-A491-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Xylanosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.543
GTEX-XPT6-0226-SM-4B65L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08452
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5164-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82324807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27566
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054111
BRD-K14476597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33926
chlorpromazine-426	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EmrE multidrug transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.62
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.930971
GSE130217_5_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K28848179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89454
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
myo-inositol:sodium symporter activity	GO Molecular Function Annotations 2025	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Activating signal cointegrator 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.728
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.625
HSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27201
HT-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ATP-binding cassette (ABC) transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.851
Amylin receptor complex 2	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.79
LRCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26642
GTEX-NFK9-0226-SM-2HMKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97338
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49996
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.456809
lateral periretromammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81244
GSE210655_3_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE200352_9_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83655
SW403	CCLE Cell Line Gene Expression Profiles	1.0	2.27828
HNRNPD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84097
Dede	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6854
r6 part of ventral gigangocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55021
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36198
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MS-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Submucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.54
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.28122
PMC4416014-pone.0125585.s010.xls-d_-BNC_network-Interactor_B_BNC1	Rummagene Transcription Factor Associations 2026	1.0	null
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02135
PMC12703266-gutjnl-75-1-s002.pdf-18-ATOH1_ATOH1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Glucose Intolerance	CTD Gene-Disease Associations	1.0	1.10942
Gastroenteritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.521
CRCGN017_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4811
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19838
Prostate adenocarcinoma_PRAD_TCGA-CH-5761-11A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Moggccm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
colorectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.30032
BRD-K52989901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43131
fluorescence	GeneRIF Biological Term Annotations	1.0	null
improved glucose tolerance	MGI Mouse Phenotype Associations 2023	1.0	null
Malabsorption, Ctcae	DisGeNET Gene-Phenotype Associations	1.0	null
Perturb_3820_KO_Satb2_SRP307573	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.985
NCI-H28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3941	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
Anorexia	DisGeNET Gene-Disease Associations	1.0	null
GSE112763,GSE112767_4_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47085
ADD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3249
r10 part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1946
A-CA-04-2009(H1N1)_0Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.79183
MMP17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1942
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852045
galactose transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7209-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sodium	CTD Gene-Chemical Interactions	1.0	null
Cardiac muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.194
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66198
moiety	GeneRIF Biological Term Annotations	1.0	null
Hexose transport	Reactome Pathways 2014	1.0	null
CAL148	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67175
Obesity	DisGeNET Gene-Disease Associations	1.0	null
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22164
BRD-K90769476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1199
POU5F1-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
HLTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40956
PAQR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41274
Hypothyroidism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
Omasum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.887
GTEX-O5YT-1826-SM-32PK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.497
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.59913
extracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.0648
TGIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28901
NANOG-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
DLG4	Pathway Commons Protein-Protein Interactions	1.0	null
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.973493
dopamine-491	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ChIP_H3K27me3_18600261_mouseWholeBrain	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r9 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22365
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37577
PMC9942993-pone.0281645.s002.xlsx-AR-as_all-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SMARCD1-25818293-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Myocardial Ischemia	DisGeNET Gene-Disease Associations	1.0	null
NCIH524	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54052
KPNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41441
SPI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.885
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.83918
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.148
GTEX-WEY5-0826-SM-4LMIH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
FTSJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06946
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.11775
Gastric mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.463
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4164-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gramine-3999	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
INCENP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57197
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.877291
premature death	MPO Gene-Phenotype Associations	1.0	null
actin-based cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.179
Leukemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.3711
decreased circulating glucose level	MPO Gene-Phenotype Associations	1.0	null
GM2493	BioGPS Cell Line Gene Expression Profiles	1.0	1.02411
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
Dicarboxylic aminoaciduria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
GSE210383_0_v_1_trim71_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23241
hsa-miR-203	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
abnormal bone trabecula morphology	MPO Gene-Phenotype Associations	1.0	null
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Integumentary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.522
inward	GeneRIF Biological Term Annotations	1.0	null
FAHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00272
GSE165122_2_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K37790543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06628
Phosphorus metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47289
hsa-miR-4643	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
absorption	GeneRIF Biological Term Annotations	1.0	null
BCL2L10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84519
GTEX-PWCY-2126-SM-48TEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-OIZH-1326-SM-3NB1H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE246053_1_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
fulvestrant-6867	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K64509887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39941
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.674941
Clara cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
Sodium/solute symporter	InterPro Predicted Protein Domain Annotations	1.0	null
contributes	GeneRIF Biological Term Annotations	1.0	null
CAMK2A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE178340_5_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Parasympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.73
Gastrointestinal Tract Vascular Insufficiency	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5192-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bile duct epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.261284
G cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.11
Pancreatic islet cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
quipazine-1789	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
who	GeneRIF Biological Term Annotations	1.0	null
Jejunal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.14
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11247
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97327
blood vessel endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.067184
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.033
GSE213650_3_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
Adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.325
transporter	GeneRIF Biological Term Annotations	1.0	null
ChIP_SUZ12_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XAJ8-0526-SM-47JYK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26885
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10605
leak	GeneRIF Biological Term Annotations	1.0	null
participates	GeneRIF Biological Term Annotations	1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.138
Angioedema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
BRD-K37656403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21476
BRD-K58996625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34183
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.78
BRD-K15290974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43427
GSE158197_0_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069069
facing	GeneRIF Biological Term Annotations	1.0	null
HHEX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27972
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
sugar	GeneRIF Biological Term Annotations	1.0	null
UNC45A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62199
hsa-miR-4645-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
Perturb_10683_OE_hURI_SRP026667	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.872
Ventromedial hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.861
r6 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09243
Chemoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.894
independent	GeneRIF Biological Term Annotations	1.0	null
Choroid plexus epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.182
BRD-K83690550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58206
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.211
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38407
benzathine benzylpenicillin-4140	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6229-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.503
CEP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78549
GRIN1	Pathway Commons Protein-Protein Interactions	1.0	null
G protein-coupled receptor heterodimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.775
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.6891
extracellular organelle	GO Cellular Component Annotations 2015	1.0	null
Mineral absorption	KEGG Pathways 2026	1.0	null
TRNP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77894
IRF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21002
ATG9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60037
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Listeriosis	DisGeNET Gene-Disease Associations	1.0	null
RKN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10295
PMC6902611-40104_2019_400_MOESM2_ESM.ods-FA-SNA-Total_of_1_054_out_of_1_627_proteins_were_considered_for_analyses_65_SNAI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
KLF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58137
abnormal circulating insulin level	MPO Gene-Phenotype Associations	1.0	null
PMC7603494-41467_2020_19353_MOESM6_ESM.xlsx-Ch_TCF3_up_and_binding_Overlapp-Unnamed_6_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
nih3t342	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.283
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
(+/-)-catechin-4837	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22462
Juxtaglomerular apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.281
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23545
free	GeneRIF Biological Term Annotations	1.0	null
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.297
L-929 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.44
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Fatty Acids	CTD Gene-Chemical Interactions	1.0	null
abnormal eating behavior	MPO Gene-Phenotype Associations	1.0	null
chloride transport	GO Biological Process Annotations 2025	1.0	null
L3MBTL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72269
BRD-K81370109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34565
YWHAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78938
pentose transmembrane transport	GO Biological Process Annotations 2023	1.0	null
Metatarsal bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.008
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053601
myo-inositol:sodium symporter activity	GO Molecular Function Annotations 2023	1.0	null
Primary somatosensory area, trunk, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04859
rsc1a1	GeneRIF Biological Term Annotations	1.0	null
RASGRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91374
MRPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55971
BRD-A80081229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18774
SMC3	ENCODE Transcription Factor Targets	1.0	null
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Portal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.025
BRD-K76755209	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13827
digestive/alimentary phenotype	MPO Gene-Phenotype Associations	1.0	null
abnormal postnatal growth	MPO Gene-Phenotype Associations	1.0	null
Muscular Diseases	CTD Gene-Disease Associations	1.0	1.0784
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.994121
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.048
Brockmann body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.337
GTEX-U8XE-1126-SM-3DB8W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2533
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5200-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17915
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40727
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0026
SNU182	DepMap CRISPR Gene Dependency	1.0	4.91123
water transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
LRRC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12128
GTEX-Q2AI-1426-SM-2S1P5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-POYW-1126-SM-48TCI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Perturb_3934_KO_TFAP2A_SRP273704	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.3665
Female reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.63
GTEX-XQ3S-0526-SM-4BOQA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14085
GTEX-R55D-0826-SM-48FEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
abnormality of urine homeostasis	HPO Gene-Disease Associations	1.0	null
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
S2 proximal cell_Kidney_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cytoprotection	GeneRIF Biological Term Annotations	1.0	null
cell projection membrane	GO Cellular Component Annotations 2025	1.0	null
BRD-K29086754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28722
GTEX-RN64-0726-SM-48FCV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
KDM5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88617
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.06808
Asthma	CTD Gene-Disease Associations	1.0	1.23584
Medulla oblongata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.005
Mouselcells	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.925
ITK_defectivemutant_125_GSE28200	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.42154
abnormal circulating hormone level	MGI Mouse Phenotype Associations 2023	1.0	null
PMC5412308__F4	PFOCR Pathway Figure Associations 2024	1.0	null
JM1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZNF428	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3638
ZNF853	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47111
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-XUYS-0126-SM-47JWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942259
GSE255432_4_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-361-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.41837
PA1	DepMap CRISPR Gene Dependency	1.0	2.00943
Acute myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.465
ZR751	CCLE Cell Line Gene CNV Profiles	1.0	1.32915
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33953
HMV-II	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848712
POU5F1	ChEA Transcription Factor Targets	1.0	null
Secretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.413
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14357
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45915
GSE215849_2_v_1_muc1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KCNIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07312
PPP1R18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66802
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
outward	GeneRIF Biological Term Annotations	1.0	null
FGFR3_knockdown_173_GSE41035	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.49796
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.318635
RPH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53027
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0028
lowdensity	GeneRIF Biological Term Annotations	1.0	null
Perturb_11321_KO_Dicer_SRP041679	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903582
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36941678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50829
Medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.305
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.048
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12414
GABRA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5047
GTEX-OHPM-1826-SM-2YUNF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
abnormality of carbohydrate metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
brush border membrane	GO Cellular Component Annotations 2015	1.0	null
EPHB6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0046478
t99-vena-cava_male_1w	MoTrPAC Rat Endurance Exercise Training	1.0	1.93024
Transient cerebral ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
MDCK-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.757
LRRFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61744
BRD-K24549321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51824
BRD-K37203945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32695
CANAGLIFLOZIN	DGIdb Drug Targets 2026	1.0	1.03788
molecular layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65337
oxidized	GeneRIF Biological Term Annotations	1.0	null
GTEX-S32W-0526-SM-4AD6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
REST_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3617	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
intermediate stratum of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18382
GTEX-P44H-0326-SM-2XCES	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051564
GSE157777_1_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
PMC12703266-gutjnl-75-1-s002.pdf-32-CDX1_CDX1	Rummagene Transcription Factor Associations 2026	1.0	null
SMC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01353
abnormal homeostasis	MPO Gene-Phenotype Associations	1.0	null
Gut epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.885
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.772
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27692
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.73846
Arteriosclerotic cardiovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.964
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.7521
TCEAL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23092
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09387
BRD-K68072222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99523
HPAC	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5725
Hairy cell leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.638
TCCSUP	CCLE Cell Line Gene Expression Profiles	-1.0	-2.39158
Perturb_10916_KO_Ghr_SRP269490	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.8659
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
observations	GeneRIF Biological Term Annotations	1.0	null
CARD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63588
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
hsa-miR-466	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
cotransporter	GeneRIF Biological Term Annotations	1.0	null
TCF3-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5557-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.72199
mRNA_ID1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Myocardial Infarction	DisGeNET Gene-Disease Associations	1.0	null
hartnup disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.10846
physiological	GeneRIF Biological Term Annotations	1.0	null
MCF7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
acids	GeneRIF Biological Term Annotations	1.0	null
cardiac	GeneRIF Biological Term Annotations	1.0	null
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PC-3_[JPC-3]	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A9WH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70029
states	GeneRIF Biological Term Annotations	1.0	null
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.125
Vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.012
Gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.821
Basal plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.518
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.594
C12orf76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19347
Tanycyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MACROH2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45983
renal distal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.437205
SUZ12-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HS6ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94448
ESRRG_Deficiency_GDS2811_637_mouse_Fetal heart - Heterozygous null mutant	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48459
SLC35F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6209
BRD-K96663576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02061
biological_process	GO Biological Process Annotations 2015	1.0	null
Basolateral part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.725
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
r7 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0622
Hyperglycemia	DisGeNET Gene-Disease Associations	1.0	null
nutrient	GeneRIF Biological Term Annotations	1.0	null
BRD-K16705729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41883
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adipocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.01
t66-lung_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	4.97512
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
transepithelial water transport	GO Biological Process Annotations 2023	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.557
BRD-K58140298	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03778
GSE100863,GSE100864_2_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
extracts	GeneRIF Biological Term Annotations	1.0	null
synaptic cleft	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.264581
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93391
BRD-K89760040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29331
jak2	GeneRIF Biological Term Annotations	1.0	null
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39571
Perturb_4485_OE_Mir29a/Mir29b1_SRP220351	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.12849
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_18400_KO_Wnk1_SRP247391	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.6803
Antropyloric mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0008
Cervical cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7906
JHH7	CCLE Cell Line Gene CNV Profiles	1.0	1.97585
form	GeneRIF Biological Term Annotations	1.0	null
GSE158834_0_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Renal outer medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.645
D502MG	DepMap CRISPR Gene Dependency	1.0	4.02647
BRD-K11008696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18368
ethosuximide-1433	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27361
hsa-miR-4729	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6147-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04035
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.37892
PMC7708794-mmc2.xlsx-DGE_table_Imm-high_vs_Imm-low-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
GFPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70589
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999789
cellular_component	GO Cellular Component Annotations 2015	1.0	null
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K78347804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00321
Brain Lower Grade Glioma_LGG_TCGA-QH-A65S-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperaldosteronism	DisGeNET Gene-Disease Associations	1.0	null
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65808
Skin Neoplasms	CTD Gene-Disease Associations	1.0	1.02821
Renal corpuscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.324
hsa-miR-607	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
BRD-K63169405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34707
Perturb_10236_KD_Kat7_SRP174052	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.10068
Leishmaniasis	DisGeNET Gene-Disease Associations	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90909
types	GeneRIF Biological Term Annotations	1.0	null
GSE109285_3_v_4_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K85996308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80607
CFAP418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62099
mRNA_RHOX6_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HASPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68982
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30374
inorganic cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-S4P3-0526-SM-4AD58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Perturb_11288_KO_Dicer_SRP041679	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Paraventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.187
GTEX-SUCS-0326-SM-32PLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30765
PDE12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98161
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.71315
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11633
Terminal bronchiole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.647
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4904-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paclitaxel_rattus norvegicus_gpl890_gse5337	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
KMS21BM	CCLE Cell Line Gene CNV Profiles	1.0	1.53072
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23804
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Chronic Constipation	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-QV44-2226-SM-447A3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
PCBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00989
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0015
intermediate stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07786
abnormal survival	MPO Gene-Phenotype Associations	1.0	null
glucosedependent	GeneRIF Biological Term Annotations	1.0	null
TEKTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02369
GTEX-OHPK-2026-SM-3MJH7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
hsa-miR-4536	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
mRNA_GADD45A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961617
GTEX-PX3G-2426-SM-48TZZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
heart	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_6688_KD_LAD1_SRP117048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.42935
DNASE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36187
renal/urinary system phenotype	MPO Gene-Phenotype Associations	1.0	null
SNCA_KO_GDS4153_528_mouse_cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
LPIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.71251
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
Uterine fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.314
insulin	GeneRIF Biological Term Annotations	1.0	null
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PLZ5-0326-SM-3P614	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Extracellular exosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE102870_3_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87366
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.34869
BRD-K43969492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52457
BRD-A44068497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10357
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7647-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oral epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.625
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-TCGA_Sparse_KM-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.914608
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1845
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Colon descendens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.861
1321N1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.49455
epididymis	HPA Tissue Protein Expression Profiles	1.0	0.777853
Collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.885
REST	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Meprin A complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.896
GTEX-XQ8I-0926-SM-4BOOF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878436
DIMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88683
Brain Lower Grade Glioma_LGG_TCGA-DU-8167-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RJ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
renal absorption	GO Biological Process Annotations 2025	1.0	null
HMBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10596
lethality at weaning	MPO Gene-Phenotype Associations	1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.059
membrane	GO Cellular Component Annotations 2015	1.0	null
Perturb_15286_KO_Trp73_SRP067006	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.25292
Lung adenocarcinoma_LUAD_TCGA-86-7953-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intercalated cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.223
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RM2N-0926-SM-48FD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15299
SMAD1-26771354-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
SNCA_KO_GDS4153_442_mouse_Cerebellum - 6 month	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WL46-0726-SM-3LK5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913386
BRD-K49368687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49229
epithelial	GeneRIF Biological Term Annotations	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
Prestwick-642-4594	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MBOAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15992
Infertility, Female	CTD Gene-Disease Associations	1.0	1.166
LAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90139
r2 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15544
Psoriasis vulgaris_Skin tissue_GSE6710	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.34974
GSE111035,GSE111040_3_v_13_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
UACC812	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09714
GSE226452_1_v_0_imiquimod_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ATP5IF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91593
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU1J-0226-SM-2TF5Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Atrophy	CTD Gene-Disease Associations	1.0	1.45352
GTEX-P44H-0726-SM-48TBT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35344
status	GeneRIF Biological Term Annotations	1.0	null
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909754
Extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Chylomicron	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.727
polymorphic layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50078
EPCAM_OE_GDS4887_342_human_IL-28B	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K08113936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48387
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916832
SPG7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00459421
description	GeneRIF Biological Term Annotations	1.0	null
Perturb_5941_KD_PHB_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.9355
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.75183
Proteinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.904
OCEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56519
apical part of cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Metabolic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.645
Cardia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.82
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.869106
ZSCAN5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66361
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.75
PPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99371
L-363	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cation transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.959752
GTEX-XV7Q-2126-SM-4BRVX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924365
Nephrocalcinosis	DisGeNET Gene-Disease Associations	1.0	null
PMC7165319-3896263.f6.xlsx-List_of_AA_outlier_pool-AA_outlier_pool_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SH3GLB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69872
Gonadotrophic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.312
KIAA0232	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90482
FARAGE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NDUFS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09986
intermediate stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54355
TMEM268	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37874
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03048
HLA-DOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84828
GTEX-QDVJ-1826-SM-2S1P3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Pancreatic duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.119
sulfabenzamide-6634	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58144
ChIP_POU5F1_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47085
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931992
GTEX-TML8-2026-SM-32QOP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE232631_0_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Supplemental somatosensory area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38382
Transit amplifying (TA) cell_Intestinal crypt_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
BRD-K07812227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59329
HOP62	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35225
SUM185PE	DepMap CRISPR Gene Dependency	1.0	3.47368
GSE179036_1_v_0_trim24_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Ileocecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.799
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02035
GTEX-R53T-0926-SM-3GADH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49551
hsa-miR-3187-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.131
SUN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48509
Congenital glucose-galactose malabsorption	ClinVar Gene-Phenotype Associations	1.0	null
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19125
BRD-K07781811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2749
PPIP5K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71387
YIPF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44068
laevis	GeneRIF Biological Term Annotations	1.0	null
means	GeneRIF Biological Term Annotations	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.127
UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.543
EBLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43944
Oral squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.012
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S27_LF_C2_24h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
Hemorrhage	CTD Gene-Disease Associations	1.0	1.23962
pathogenesis	GO Biological Process Annotations 2015	1.0	null
Cortical amygdalar area, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24295
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K36me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85722200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51797
generate	GeneRIF Biological Term Annotations	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Hyperactive Bowel Sounds	DisGeNET Gene-Phenotype Associations	1.0	null
Arterial blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.354
SUZ12-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
thus	GeneRIF Biological Term Annotations	1.0	null
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
r10 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97347
H3K27me3_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9657_KD_NKX25_SRP306591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CD63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49011
Glossopharyngeal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
sodiumglucose	GeneRIF Biological Term Annotations	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.764
BRD-K70315531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0757
UBIAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95626
Autonomic neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
GTEX-U3ZN-1026-SM-4DXTC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K60430111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22938
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75645
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29208
Gastroparesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.42
Pulmonary Disease, Chronic Obstructive	CTD Gene-Disease Associations	1.0	1.13963
porcine aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.429165
GSE228727_2_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5998
BRD-K95577144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10001
barrier	GeneRIF Biological Term Annotations	1.0	null
IEC-18 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.836
LAPTM4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40728
abnormal skeleton morphology	MPO Gene-Phenotype Associations	1.0	null
SNUC4	CCLE Cell Line Gene Expression Profiles	1.0	1.49729
PRDM14-21183938-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
DAPAGLIFLOZIN PROPANEDIOL	DGIdb Drug Targets 2026	1.0	0.778412
transporter activity	GO Molecular Function Annotations 2015	1.0	null
TM-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.026
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.56738
Egg white	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.723
Outer kinetochore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.747
Hypokalemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.374
Meconium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.749
Coronary Arteriosclerosis	DisGeNET Gene-Disease Associations	1.0	null
Cecum cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.727
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9275
BRD-K90697692	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4482
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05279
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86374
GTEX-OIZH-0226-SM-2YUMH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
ZNF676	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38427
CRCGN011_HEPG2_24H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0473
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2431
bed nucleus of the stria terminalis, laterocentral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92051
Abdomen Distended	DisGeNET Gene-Phenotype Associations	1.0	null
involving	GeneRIF Biological Term Annotations	1.0	null
BRD-K86109840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04607
METAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69114
Liver Cirrhosis	CTD Gene-Disease Associations	1.0	1.29875
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K91944762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21155
Lung non-small cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23223
there	GeneRIF Biological Term Annotations	1.0	null
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
colorectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.301039
Bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
abnormal small intestine morphology	MPO Gene-Phenotype Associations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24367
EW7	DepMap CRISPR Gene Dependency	1.0	2.02108
ATP2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50634
Gut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.173
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.728
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.00602
SUZ12	ChEA Transcription Factor Targets	1.0	null
Soleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.043
496100447_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58861
PMC11384093-mmc1.xlsx-886-drug_target-VDR_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K09414286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04213
COLO205	CCLE Cell Line Gene Expression Profiles	1.0	1.41339
GTEX-XUW1-0226-SM-4BOOS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_14539_KO_Kras_SRP311976	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.13522
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10493
Sucrose	CTD Gene-Chemical Interactions	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33263
reside	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gastric ulcer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE148692,GSE148695_1_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P4PQ-0226-SM-2S1NK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K73581966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.44436
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40691
hsa-miR-140-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
G57321FI	GlyGen Glycosylated Proteins	1.0	null
Nephrolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.429
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.834617
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29175
Cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.998
Extrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
GOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25211
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.172038
HCMV_TB40E_24Hour_19951172_GSE14816	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.16143
PMC7887593-ADVS-8-2003526-s002.xlsx-LCM_AR_vs_BR-Gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29125
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.38855
VEZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7305
G29068FM	GlyGen Glycosylated Proteins	1.0	null
MARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10855
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Hyperglycemia	CTD Gene-Disease Associations	1.0	1.60105
BRD-A68323834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11222
Urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.609
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.37624
BRD-K02024244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09121
SCC25	CCLE Cell Line Gene Expression Profiles	-1.0	-2.10878
glucose import across plasma membrane	GO Biological Process Annotations 2023	1.0	null
hsa-miR-3653	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
kinase	GeneRIF Biological Term Annotations	1.0	null
Canagliflozin	DrugBank Drug Targets	1.0	null
apical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.309986
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
JARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32952
slc5a1	GeneRIF Biological Term Annotations	1.0	null
Nephrotic syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
ABHD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40333
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.946
Infundibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.953
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.978858
Apical part of cell	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
membrane region	GO Cellular Component Annotations 2015	1.0	null
trafficking	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-3120-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.327
correlates	GeneRIF Biological Term Annotations	1.0	null
Uterine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.964
sugars	GeneRIF Biological Term Annotations	1.0	null
gallbladder_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.903509
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056411
ZXDC1_KD_GSE45417_686_human_U937	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GRIN2A	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7817-01B-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leads	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-548ag	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Colonic mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.499
PCDHB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49937
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.91739
Hypokalemia	CTD Gene-Disease Associations	1.0	1.19246
galactose transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
extracellular matrix part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051024
principal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26664
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.0194
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2ML-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oxyntic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.124
GTEX-WH7G-0326-SM-3NMBH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34796
LLC-PK1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.841
GSE166004_3_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63725
Perturb_9765_KO_Ikbkb/Shp2_SRP285005	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.97805
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13706
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.382
GSE203329_0_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
galactose	GeneRIF Biological Term Annotations	1.0	null
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21180458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26717
GTEX-R55C-1126-SM-48FCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07937
IPO8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9802
dorsolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.893306
GTEX-XGQ4-0626-SM-4AT56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
periventricular stratum of Dg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24295
RCOR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73267
Cardiac muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.044
SOX2-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormal circulating glucose level	MGI Mouse Phenotype Associations 2023	1.0	null
19249085-TableE4	GeneSigDB Published Gene Signatures	1.0	null
NOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52558
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19993
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52425
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1304
Proximal tubule transport	WikiPathways Pathways 2024	1.0	null
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.492
OTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51177
single-organism localization	GO Biological Process Annotations 2015	1.0	null
Candidiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
Respiratory Hypersensitivity	CTD Gene-Disease Associations	1.0	1.02634
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Glycogen storage diseases	Reactome Pathways 2014	1.0	null
PACADD188	DepMap CRISPR Gene Dependency	1.0	2.31188
ZFY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86873
CYTH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97257
GTEX-R55C-1926-SM-2TF4K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
JKAMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35113
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28318
Inward rectifying potassium channel	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.729
Mitochondrial outer membrane translocase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.939
Metabolic Acidosis	DisGeNET Gene-Phenotype Associations	1.0	null
T-84 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.369
H3K9me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC4013402__F1	PFOCR Pathway Figure Associations 2023	1.0	null
GTEX-WL46-0126-SM-3TW8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
COLO205	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S23_LF_C1_24h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K04722226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04519
GSE71491_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-QLQW-0626-SM-447A6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-WHPG-1026-SM-3NMBA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901251
glucose transmembrane transport	GO Biological Process Annotations 2023	1.0	null
GSE153189_1_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
effect	GeneRIF Biological Term Annotations	1.0	null
GTEX-QDT8-0226-SM-32PL4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Enterocyte_Small intestine_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Penile disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
BRD-K75981085	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51533
dfs	GeneRIF Biological Term Annotations	1.0	null
Glucose transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.686
early endosome	GO Cellular Component Annotations 2023	1.0	null
alpha-glucoside transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92411
Prediabetes syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.336
Taste bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.86
Cough	CTD Gene-Disease Associations	1.0	1.12426
CAPN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66678
GTEX-XUZC-0526-SM-4BOPF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-NPJ8-1726-SM-2YUNB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
RPL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92319
sodium ion import across plasma membrane	GO Biological Process Annotations 2023	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Intestinal juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.988
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9207
BRD-K90697694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24323
Intestinal Atresia	DisGeNET Gene-Disease Associations	1.0	null
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.083
empagliflozin	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
ventral posterolateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19983
REST_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12199
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDT8-1026-SM-43V6X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K98225007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21407
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4204
LHX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60777
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.976233
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76529
TWF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50391
Pancreatic adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
likely	GeneRIF Biological Term Annotations	1.0	null
BRD-K43336921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2957
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cyclin B2-CDK1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.998
YIPF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26022
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.688139
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06901
MMP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88593
Hyperekplexia 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
PMC11447041-41598_2024_74391_MOESM2_ESM.xlsx-E_ATF4-def_vs_HCT116_Tg8-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
apical	GeneRIF Biological Term Annotations	1.0	null
PMC12661646-dmm-18-052290-TableS5.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.775014
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4878-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Podocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.637
Acute Myeloid Leukemia_LAML_TCGA-AB-2848-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Morbid obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.686
GTEX-RTLS-1226-SM-46MUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
properly	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_MCF10A.TP53.M_24H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0911
r10 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33289
fucose transmembrane transport	GO Biological Process Annotations 2023	1.0	null
Brain endothelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.796
MAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78632
GTEX-PWN1-1826-SM-2S1PE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Feather	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.017
Human brain microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
supragenual nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00539
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
critically	GeneRIF Biological Term Annotations	1.0	null
regulated	GeneRIF Biological Term Annotations	1.0	null
TOFOGLIFLOZIN ANHYDROUS	DGIdb Drug Targets 2026	1.0	1.03788
Lung squamous cell carcinoma_LUSC_TCGA-60-2707-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
extending	GeneRIF Biological Term Annotations	1.0	null
GSE224131_3_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
aimed	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5377-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19G-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTPRK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00525352
ATP7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50796
GSE226355,GSE226357_1_v_4_ybx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.066
Glycocalyx	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.22
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Ovarian disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
Renal proximal tubule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.176
G58001LT	GlyGen Glycosylated Proteins	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KH-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
damages	GeneRIF Biological Term Annotations	1.0	null
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38407
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.972293
lethality at weaning, complete penetrance	MGI Mouse Phenotype Associations 2023	1.0	null
Galactosemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.365
abdominal distention	HPO Gene-Disease Associations	1.0	null
Perturb_4499_KO_Cftr_SRP067491	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
ANKRD39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58987
FAM217B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48737
Brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.5
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.450271
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5859
PMC12822963-pone.0339296.s005.xlsx-Sheet1-HIF1A_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
LTA4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0555
leptin	GeneRIF Biological Term Annotations	1.0	null
GSE139987_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
describes	GeneRIF Biological Term Annotations	1.0	null
SELENOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8321
BRD-K73357447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08387
ongoing	GeneRIF Biological Term Annotations	1.0	null
Sleep disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
smallintestine_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.49215
GSE216538_1_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
CHST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51241
RNF2-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Disorders of fructose metabolism	WikiPathways Pathways 2024	1.0	null
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Microvillus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.289
IEC-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.499
BRD-K69613314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4103
BRD-K67533212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59302
PMC9942993-pone.0281645.s002.xlsx-AR_as_all_as_maintained-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.689013
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table6_gnomAD_EUR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
Epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.241
Interrenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.514
Renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.039
BRICD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04569
xylometazoline-2270	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAPK8IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01134
GTEX-QCQG-0126-SM-48U27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GP2D	CCLE Cell Line Gene Expression Profiles	1.0	1.78539
accumbens nucleus, core domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26585
docebenone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35846
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
HCC15	DepMap CRISPR Gene Dependency	1.0	3.03403
Vascular Diseases	CTD Gene-Disease Associations	1.0	1.15391
AMPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55921
BAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05322
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59204
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PARP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94913
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
mediates	GeneRIF Biological Term Annotations	1.0	null
RYBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83938
GTEX-XQ3S-0626-SM-4BOOB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47991
Newcastle disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.242
BRD-K11419664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91768
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
exhibit	GeneRIF Biological Term Annotations	1.0	null
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
APUD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.576
L-428	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23973
GSE191015_1_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A550-01A-61R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10794847-mmc2.xlsx-PBRM1_KD_up-Table_S1_Differentially_expressed_genes_with_PBRM1_knockdown_in_the_progenitor_state_Related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FBXO45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51507
Neuralgia	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K33016067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57751
colorectal	GeneRIF Biological Term Annotations	1.0	null
BRD-K22338979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25695
TFCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10801
mantle zone of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15498
r9 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23458
Kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.87
suggesting	GeneRIF Biological Term Annotations	1.0	null
BRD-K24970278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4196
diabetes	GeneRIF Biological Term Annotations	1.0	null
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.155
Renal tubular transport disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.1
orlistat-6383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.984327
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LB-11A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K90151990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25732
Perturb_3935_KO_TFAP2A_SRP273704	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
TRAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84295
decreased body weight	MGI Mouse Phenotype Associations 2023	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.39673
SW1463	GDSC Cell Line Gene Expression Profiles	1.0	2.0813
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Ileum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.84
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:M23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0675
SPG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49518
BRD-K60701773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2185
Style	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.409
SIRT6	ENCODE Transcription Factor Targets	1.0	null
SP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.974012
GSE149901_3_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal glucose homeostasis	MPO Gene-Phenotype Associations	1.0	null
conceptus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.10314
increased bone trabecula number	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K53544328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72941
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
sergliflozin 	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
Vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE200839,GSE233826_3_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPL-1326-SM-3MJGG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE248858_4_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060841
bemegride-3051	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Neovascularization, Pathologic	CTD Gene-Disease Associations	1.0	1.21631
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43852
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
decreased total tissue mass	MPO Gene-Phenotype Associations	1.0	null
Uterine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.031
tRNA-splicing ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.631
Connecting tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.493
glucocorticoidinducible	GeneRIF Biological Term Annotations	1.0	null
SLC4A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03133
GSE114232_8_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
water	GeneRIF Biological Term Annotations	1.0	null
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4XY-0526-SM-46MW1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
mRNA_T_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MGST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16171
HSPA1A	Hub Proteins Protein-Protein Interactions	1.0	null
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Familial combined hyperlipidaemia_Blood monocyte_GSE11393	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.5176
EIF3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00877
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
19249085-Table3	GeneSigDB Published Gene Signatures	1.0	null
abnormal femur morphology	MPO Gene-Phenotype Associations	1.0	null
CCDC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14621
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39437
ChIP_NANOG_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTMR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89212
hsa-miR-342-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K00551139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75743
Left Ventricular Dilatation	DisGeNET Gene-Disease Associations	1.0	null
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C32	CCLE Cell Line Gene CNV Profiles	1.0	1.46049
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Adermatoglyphia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.776
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07674
GTEX-R55G-0426-SM-48FDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-U3ZN-0426-SM-4DXSH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
vesicle	GeneRIF Biological Term Annotations	1.0	null
PMC3705551__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GSE183335,GSE183351_3_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Heart ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.495
Colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.555
minute	GeneRIF Biological Term Annotations	1.0	null
NTHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19508
SNCA_KO_GDS4153_444_mouse_Cerebellum - 21 month	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.149
RBM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13531
presentation	GeneRIF Biological Term Annotations	1.0	null
GTEX-REY6-0326-SM-2TF5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941661
GTEX-XUZC-1426-SM-4BRV3	GTEx Tissue Sample Gene Expression Profiles	1.0	3.00157
GSE148066,GSE157787_11_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
part	GeneRIF Biological Term Annotations	1.0	null
CAL-85-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19295
Cortical amygdalar area, anterior part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25717
CRCGN017_MCF10A.TP53.M_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1703
lower basal lateral hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26742
DETROIT562	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02043
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25Y-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
19658189-TableS3	GeneSigDB Published Gene Signatures	1.0	null
ZNF813	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42297
GSE133213_6_v_5_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.744122
potent	GeneRIF Biological Term Annotations	1.0	null
CHRNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20512
GTEX-T5JW-0426-SM-4DM7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Septicemia	DisGeNET Gene-Disease Associations	1.0	null
chloride transmembrane transport	GO Biological Process Annotations 2025	1.0	null
GSE126463_1_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A88381870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40173
protein-containing complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.016
IGF1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53277
causes	GeneRIF Biological Term Annotations	1.0	null
GTEX-VUSG-1426-SM-3GIJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09071
Perturb_10230_KD_FOXC1_SRP068208	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.86152
BRD-K69543414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1007
3T3-L1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.504
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
intermediate stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74383
renal	GeneRIF Biological Term Annotations	1.0	null
NCIH1092	DepMap CRISPR Gene Dependency	1.0	3.10933
intermediate stratum of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42225
MHH-ES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE232944_1_v_0_ctnnb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ETNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33914
POU4F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62541
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_KLF4_19030024	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49757
abnormal circulating glucose level	MPO Gene-Phenotype Associations	1.0	null
Apical plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.806
cardiovascular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Heart	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.121
Vertebrate muscular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.37
abnormal renal glucose reabsorption	MPO Gene-Phenotype Associations	1.0	null
CHAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84205
AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20108
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4834
intermediate stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04706
Glomerulosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
ZNF136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38258
signals	GeneRIF Biological Term Annotations	1.0	null
Glycogen granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.661
BRD-K13788250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20731
Congenital diarrhea 5 with tufting enteropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.801
Cystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
gate	GeneRIF Biological Term Annotations	1.0	null
colonic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.122253
BRD-K92210988	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40893
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_27_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
apoptotic	GeneRIF Biological Term Annotations	1.0	null
GTEX-QV31-1326-SM-2S1QE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Cardiofibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.228
SFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78699
BRD-K98408839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07156
HCC1143	CCLE Cell Line Gene Expression Profiles	1.0	1.64089
clopidol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02406
Hyperphosphatemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
ASH1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98871
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.374666
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
hsa-miR-4692	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
hsa-miR-3064-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE157233_2_v_4_a1cf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreatic Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XV7Q-2426-SM-4BRV8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905284
GTEX-NPJ7-1726-SM-2YUNA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
hsa-miR-3934	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.584
LS-1034	GDSC Cell Line Gene Expression Profiles	1.0	1.73311
GSE136311_1_v_0_lyz2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211226_1_v_2_sirpa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
glut2	GeneRIF Biological Term Annotations	1.0	null
rescue	GeneRIF Biological Term Annotations	1.0	null
Chronic Diarrhea	DisGeNET Gene-Disease Associations	1.0	null
cell projection membrane	GO Cellular Component Annotations 2023	1.0	null
BRD-K19958830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35559
Perturb_15778_KO_Nmnat2_SRP360949	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.43013
chemdependency	GAD High Level Gene-Disease Associations	1.0	0.293278
oocytes	GeneRIF Biological Term Annotations	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PMC9942993-pone.0281645.s002.xlsx-AR-as_non-adaptive-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.22436
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.753713
Wing	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.962
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.99419
variety	GeneRIF Biological Term Annotations	1.0	null
r9 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66723
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84509
NCIH2052	DepMap CRISPR Gene Dependency	1.0	2.9978
RAD21	ENCODE Transcription Factor Targets	1.0	null
HELLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6043
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AFF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46405
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0015
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45742
fucose transmembrane transport	GO Biological Process Annotations 2025	1.0	null
GTEX-TMMY-0126-SM-4DXTP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935529
uterine endometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.517678
GSE192771_2_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Congenital malabsorptive diarrhea 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.269
Mitral cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.734
ZNF717	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52355
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-A04691170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05731
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT5A	ChEA Transcription Factor Targets	1.0	null
intracellular vesicle	GO Cellular Component Annotations 2025	1.0	null
Fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.003
COLO-205	GDSC Cell Line Gene Expression Profiles	1.0	2.52856
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913253
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055169
GTEX-U4B1-0326-SM-3DB8K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08001
TMEM9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28271
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9471
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RNF2	ChEA Transcription Factor Targets	1.0	null
BRD-K09328667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72872
GLP 1 secretion from intestine to portal vein	WikiPathways Pathways 2024	1.0	null
GSE145215_0_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
metabolic	GAD High Level Gene-Disease Associations	1.0	0.293278
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848867
BRD-K47784292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32874
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68608
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.994
GTEX-O5YV-0326-SM-2I5H2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18153
Urinary tract infection	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.424
smallintestine_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.60048
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.979519
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Vulvovaginitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.856
superficial stratum of THyB-D	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40255
LHX1_NULL MUTATION - Ablation_GDS1748_749_mouse_Embryonic kidneys (from day E18.5)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Renal glomerular capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.771
TGF-beta_OE_GDS2974_137_mouse_corneas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE185944_2_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SREBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98964
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.241
Renal Insufficiency	CTD Gene-Disease Associations	1.0	1.35647
heterologous	GeneRIF Biological Term Annotations	1.0	null
Osteoporosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
Cadmium	CTD Gene-Chemical Interactions	1.0	null
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S01_LF_C1_3h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
ABHD16B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.69046
bcl2	GeneRIF Biological Term Annotations	1.0	null
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.1368
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38476
Transport of small molecules	Reactome Pathways 2024	1.0	null
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.13279
H3K27me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Mucous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.993
BMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51158
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K30530468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19289
active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5898
Rectum adenocarcinoma_READ_TCGA-AF-2693-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Villus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.654
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.777
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7926-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182727_1_v_0_busulfan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.83707
GTEX-U4B1-1226-SM-4DXT7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE150215_1_v_0_etl4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cause	GeneRIF Biological Term Annotations	1.0	null
Abdominal aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.042
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table8_gnomAD_AFR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
CREB3L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8039
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.41
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
Gastric epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.955
boost	GeneRIF Biological Term Annotations	1.0	null
organic hydroxy compound transport	GO Biological Process Annotations 2023	1.0	null
plant-type cell wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.947
MED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08695
BRD-K78741913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10618
PMC7923230__F6	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
NKX1-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37227
NCIH727	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72693
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Gastrointestinal endocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.573
metal ion transport	GO Biological Process Annotations 2023	1.0	null
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6435
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.29719
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SA-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Glomerular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.646
hsa-miR-4514	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
DACT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15857
Subapical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.647
Perturb_3907_KO_DUSP6_SRP229874	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Small intestine mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.475
PMC5412308__F4	PFOCR Pathway Figure Associations 2023	1.0	null
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WM983B	DepMap CRISPR Gene Dependency	1.0	3.29566
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r6 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0033
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGFR	Pathway Commons Protein-Protein Interactions	1.0	null
Subcutis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.423
Colorectal adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.99
inhibition	GeneRIF Biological Term Annotations	1.0	null
GTEX-RU72-0826-SM-46MUS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
laterostriatal stripe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47268
Glucose Tolerance Test	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K17956418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30313
cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-XQ8I-0226-SM-4BOPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33429
SUZ12-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
density	GeneRIF Biological Term Annotations	1.0	null
GLYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46262
TM-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.339
GSE185953_1_v_3_tlr3_human	RummaGEO Gene Perturbation Signatures	1.0	null
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047351
does	GeneRIF Biological Term Annotations	1.0	null
GRIN2D	Pathway Commons Protein-Protein Interactions	1.0	null
Atherosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.963
BRD-K41355839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82518
PMC9942993-pone.0281645.s002.xlsx-AR_as_non-adaptive_as_maint-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210476_9_v_7_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
GTEX-PX3G-0326-SM-2I3EO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36726
Perturb_3415_KO_Cdx2_SRP093647	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE155162,GSE155169_1_v_0_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41128
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.29522
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
BRD-K18176829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54741
prostate	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.12787
PINLYP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70784
membrane	GeneRIF Biological Term Annotations	1.0	null
Breast Cancer_Mammary Gland Tissue_GSE1379	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.22383
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.02404
Muscularis mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
JARID1B-DAIN-22020125-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958499
abnormality of urine glucose concentration	HPO Gene-Disease Associations	1.0	null
chr22_31969737_G_A_b38	GTEx eQTL 2025	1.0	1.62015
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
USP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89891
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_39_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Muscular coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.019
Colorectal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.457
outer CP in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21895
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.145747
PMC12808183-41598_2025_31780_MOESM7_ESM.pdf-1-FOXN1_FOXN1	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM258	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29118
BRD-K63401195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37986
HCC56	CCLE Cell Line Gene Expression Profiles	1.0	2.64934
HMGB1P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3059
SALL4	ChEA Transcription Factor Targets	1.0	null
galactose transmembrane transport	GO Biological Process Annotations 2023	1.0	null
disulfide	GeneRIF Biological Term Annotations	1.0	null
POU5F1-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NRF2 pathway	WikiPathways Pathways 2024	1.0	null
Fanconi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.461
hippocampus (hippocampal formation)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.97358
modulates	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17291
Nipple	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.201
RHOXF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31705
ChIP_TCF3_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
strawberry	GeneRIF Biological Term Annotations	1.0	null
GSE130864_0_v_1_tincr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PSPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88854
GSE147876,GSE147877_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A2780	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE144115_2_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54622
Essential hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
ANO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98517
hsa-miR-641	TargetScan Predicted Conserved microRNA Targets	1.0	0.165047
BRD-K51446586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49163
Prostate adenocarcinoma_PRAD_TCGA-HC-7744-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intestinal D-glucose absorption	GO Biological Process Annotations 2023	1.0	null
ZNF491	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11643
Traumatic brain injury	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.054
anterior cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28969
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059209
medial part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42861
targeting	GeneRIF Biological Term Annotations	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.680656
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.772
Scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.949
Renal distal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.436
IRS4_KO_GDS1219_306_mouse_brown preadipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
oncoprotein	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE80098,GSE80366_0_v_6_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.703536
BRD-A07195938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10542
upper basal lateral hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0787
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.409
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133213_11_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Proventriculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.209
Cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.242
Inner mucus layer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.611
NDUFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20536
uterine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.371994
BRD-K16937802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28382
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.8538
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
well	GeneRIF Biological Term Annotations	1.0	null
cell-cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-PSDG-0926-SM-2I5FP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50741
berry	GeneRIF Biological Term Annotations	1.0	null
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20799
TGFBR3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85664
PMC10891378-tau-13-01-91-supplementary.pdf-17-TBX1_TBX1	Rummagene Transcription Factor Associations 2026	1.0	null
Slit diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.744
GTEX-S7SE-0526-SM-2XCD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
ion transport	GO Biological Process Annotations 2015	1.0	null
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Supplementary_Table_2_Differentially_expressed_genes_upon_knockdown_of_SUFU_compared_to_control_in_HCC1954_cells_Related_to_Figure_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic alpha cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.296
Lung adenocarcinoma_LUAD_TCGA-86-A4P7-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE181517_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hydrophobicity	GeneRIF Biological Term Annotations	1.0	null
GTEX-XV7Q-2226-SM-4BRVY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chloride transmembrane transport	GO Biological Process Annotations 2023	1.0	null
ASIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53069
Perturb_16459_KO_Nf1_SRP155510	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.4754
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
NCIH1573	DepMap CRISPR Gene Dependency	1.0	3.17754
Epididymal white adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.957
Triple-Negative Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
explained	GeneRIF Biological Term Annotations	1.0	null
GTEX-QCQG-0726-SM-48U1Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Mitochondrial permeability transition pore complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.29
superficial stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22426
studies	GeneRIF Biological Term Annotations	1.0	null
polyphenols	GeneRIF Biological Term Annotations	1.0	null
tsA-201 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02242
Focal segmental glomerulosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.28672
return	GeneRIF Biological Term Annotations	1.0	null
Rectum adenocarcinoma_READ_TCGA-DY-A0XA-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.594
CTCF	ENCODE Transcription Factor Targets	1.0	null
SPEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88569
Disorders of galactose metabolism 	WikiPathways Pathways 2024	1.0	null
Pinosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.651
Glial cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.044
ChIP_PRDM14_21183938	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.858
TRAPPC2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3076
Muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.37
OK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.865
CRCGN016_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26143
interact	GeneRIF Biological Term Annotations	1.0	null
BRD-K44426506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03473
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K56055036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61119
abnormal limb morphology	MPO Gene-Phenotype Associations	1.0	null
parasubthalamic nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47453
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.615
PMC3705551__F2	PFOCR Pathway Figure Associations 2023	1.0	null
BRD-K98856654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19181
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24941
INAFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15089
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
inorganic cation import across plasma membrane	GO Biological Process Annotations 2025	1.0	null
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Nrd1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.936
Endomembrane system	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
IKZF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22616
Neutropenia	CTD Gene-Disease Associations	1.0	1.15022
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.214
Amino acid transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.378
HOXD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82436
BRD-K18332967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01787
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49474
ZNF202	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47465
ZNF775	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02179
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.9758
Peripheral artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
depression	GWASdb SNP-Phenotype Associations	1.0	0.57836
NANOG-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN008_HEPG2_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2006
REC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49765
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46193
GTEX-XPT6-0426-SM-4B672	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
NUGC4	CCLE Cell Line Gene Expression Profiles	1.0	2.22404
colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.271256
Perturb_958_KO_Abca3_SRP116949	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.63263
Gestational diabetes	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
Testicular cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.224
ZNF800	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92847
GTEX-O5YV-1626-SM-2YUNJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Apical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.065
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.478
SF3B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64251
complete lethality at weaning	MPO Gene-Phenotype Associations	1.0	null
pancuronium bromide-2909	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53J-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DHX32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31872
TOLLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19026
BRD-K75380271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3369
PMC10773028-40364_2023_552_MOESM2_ESM.xlsx-Variants_sheet-TFT_TBXT	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ8-1826-SM-2YUNC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-TKQ1-1326-SM-4DXU7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
ZNF74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31935
Paneth cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.75
FAM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29615
Postgastrectomy syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.451
PPM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36129
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cation transport	GO Biological Process Annotations 2015	1.0	null
Pneumonia	CTD Gene-Disease Associations	1.0	1.40036
t67-small-intestine_female_1w	MoTrPAC Rat Endurance Exercise Training	1.0	1.50555
KM-H2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.95587
PTPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64978
hexose transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
GTEX-XGQ4-0526-SM-4AT6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25854
BRD-K90408478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52089
hpv18	GeneRIF Biological Term Annotations	1.0	null
BRD-K20061970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.44445
Sarcolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.68
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
INO80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02775
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Hypertrophic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
Growth Disorders	CTD Gene-Disease Associations	1.0	1.38863
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-TML8-0926-SM-4DXSJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Bronchial disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.317
hsa-miR-548ai	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE241701_4_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5260-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K88313926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19997
SLC19A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62875
agranular insular cortex (area Iag)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.97419
Plasma lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.193
ADAM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40635
sodium ion transport	GO Biological Process Annotations 2023	1.0	null
prognosis	GeneRIF Biological Term Annotations	1.0	null
GSE116299_0_v_3_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IFT25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16903
Macrophage foam cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.73
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00994
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
voltage-gated sodium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.76
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_57_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
ADGRA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98945
Perturb_16478_OE_Klk6_SRP245408	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10605
CRCGN015_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6714
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840827
PPP2R1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12815
Lung squamous cell carcinoma_LUSC_TCGA-43-6771-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS411N	CCLE Cell Line Gene Expression Profiles	1.0	1.74339
BRD-K60166659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19825
periventricular stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19342
GTEX-WI4N-1126-SM-3LK7Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
tissues	GeneRIF Biological Term Annotations	1.0	null
resolution	GeneRIF Biological Term Annotations	1.0	null
GTEX-QDVN-0326-SM-2I3FS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62047
ZDHHC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94004
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05155
outer	GeneRIF Biological Term Annotations	1.0	null
ZNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7403
Sarcoma_SARC_TCGA-DX-A3UB-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.2437
Aleurone layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
aorta endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.171831
RAMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26649
NCI-H847	COSMIC Cell Line Gene Mutation Profiles	1.0	null
charge	GeneRIF Biological Term Annotations	1.0	null
monoatomic anion transmembrane transport	GO Biological Process Annotations 2023	1.0	null
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ChIP_NANOG_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
EMPAGLIFLOZIN	DGIdb Drug Targets 2026	1.0	0.622729
Bile canaliculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.939
coupling	GeneRIF Biological Term Annotations	1.0	null
FGFR3_knockdown_34_GDS4454	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.498
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.88
Hypertriglyceridemia	CTD Gene-Disease Associations	1.0	1.19379
Perturb_11866_OE_Il13_ERP005901	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
ACAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93467
BRD-K73730918	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50955
cell junction	GO Cellular Component Annotations 2015	1.0	null
Right colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.387
Mucus layer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.078
Inner medullary collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.175
BRD-K43240808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44047
MDCK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.563
abnormal circulating hormone level	MPO Gene-Phenotype Associations	1.0	null
SREK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66371
CRCGN008_HEPG2_24H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3583
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K71109636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46076
GSE169356_0_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
targeted	GeneRIF Biological Term Annotations	1.0	null
extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
hsa-miR-4673	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
Duodenum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.817
Irritable bowel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.709
ZNF37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23222
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Enteroendocrine cell_Intestinal crypt_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
residues	GeneRIF Biological Term Annotations	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE88819_5_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R53T-0726-SM-48FCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
truncated	GeneRIF Biological Term Annotations	1.0	null
renal D-glucose absorption	GO Biological Process Annotations 2025	1.0	null
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857049
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4961
Malignant astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.34702
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.932912
GTEX-X4XX-0011-R2A-SM-3P623	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-WYVS-1726-SM-3NMAY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899183
Ulcerative colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.501
GSE145215_2_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K47962810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61886
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.501
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044582
Supplemental somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10033
GP5d	GDSC Cell Line Gene Expression Profiles	1.0	1.74593
Metabolic Syndrome X	DisGeNET Gene-Disease Associations	1.0	null
HLCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92098
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Pectoral muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.366
r9 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23413
BRD-K59064238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00188
GTEX-REY6-1026-SM-2TF4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972676
SPAG9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60593
BRD-K61551386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53379
Diabetes insipidus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
describe	GeneRIF Biological Term Annotations	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S12_LF_C1_8h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
Pyruvate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.462
CMK115	DepMap CRISPR Gene Dependency	1.0	2.54599
ingestion	GeneRIF Biological Term Annotations	1.0	null
GSE210655_1_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.412
GTEX-R55D-1826-SM-48FEF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23626
metal ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
mortality/aging	MPO Gene-Phenotype Associations	1.0	null
PAWR	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S16_LF_C2_8h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K32423836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29031
inhibiting	GeneRIF Biological Term Annotations	1.0	null
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910452
extracellular region	LOCATE Curated Protein Localization Annotations	1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Albedo	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
Trachea	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05163
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
Lymphatic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.29
Renal cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
RASD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65596
hsa-miR-593	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Filtration diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.743
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4859-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04653
Cholera	DisGeNET Gene-Disease Associations	1.0	null
kidney	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.11399
GSE234340_12_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ileal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.43414
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
uptake	GeneRIF Biological Term Annotations	1.0	null
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
CRCGN012_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38856
membrane region	LOCATE Curated Protein Localization Annotations	1.0	null
HT-29-MTX cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.94
myo-inositol transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
Colon sigmoideum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.2059
GTEX-XBED-1426-SM-4AT4G	GTEx Tissue Sample Gene Expression Profiles	1.0	3.24204
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.86437
aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.178765
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
t99-vena-cava_female_4w	MoTrPAC Rat Endurance Exercise Training	-1.0	-23.2318
A704	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870118
A2058	COSMIC Cell Line Gene Mutation Profiles	1.0	null
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66708
BRD-K48029682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10591
internal globus pallidus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51866
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table7_gnomAD_AMR_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157777_1_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Caco-2/TC7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.547
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.151
Orphan transporters	Reactome Pathways 2014	1.0	null
Metabolism of carbohydrates	Reactome Pathways 2014	1.0	null
Renal proximal tubule epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.647
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41826
MBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10692
GTEX-S95S-1626-SM-2XCDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
PMC12143321-mmc3.xlsx-Sheet1-NR3C2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
DHODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05932
BRD-K20435953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12818
increased length of long bones	MPO Gene-Phenotype Associations	1.0	null
Glucosidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.322
Perturb_16477_KO_Cyp26b1_SRP015254	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BRD-K77987907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23217
Primary somatosensory area, lower limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06623
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.02386
Lung adenocarcinoma_LUAD_TCGA-55-7570-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6702
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57328
sglt1dependent	GeneRIF Biological Term Annotations	1.0	null
PELO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31859
MTRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6867
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.179896
BRD-K03515786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38791
Heart	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cis-Golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.174
GSE162276_2_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ChIP_ZIC3_20872845	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSTK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57886
myo-inositol transport	GO Biological Process Annotations 2023	1.0	null
PMC4531812-13058_2015_618_MOESM11_ESM.xlsx-Metabric_Sparse_KM_976-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
COLO678	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7554
Heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.411
Yolk plasma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.528
Conceptus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.419
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K48681121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16713
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	-1.0	-2.21518
GSE200839,GSE233826_2_v_0_tnrc18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PLZ4-1326-SM-2S1O7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
cell projection membrane	GO Cellular Component Annotations 2015	1.0	null
BRD-K35341092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54179
PIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52367
COPI-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.079
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.337
Stolon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.523
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111247_11_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Vascular Insufficiency Of Intestine	DisGeNET Gene-Disease Associations	1.0	null
large	GeneRIF Biological Term Annotations	1.0	null
Guanylate cyclase complex, soluble	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.218
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TNFRSF10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98354
PMC7495487-41598_2020_71030_MOESM2_ESM.xlsx-Sheet1-NR1A1_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-93-7348-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sleep apnea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
GTEX-WFON-1426-SM-4LVMT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09321
SAMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48154
Renal proximal tubule epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
Perturb_16479_OE_Klk6_SRP245408	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-QCQG-1826-SM-2S1P2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-P4PQ-1726-SM-3NB15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Fluorouracil	CTD Gene-Chemical Interactions	1.0	null
HMGA2_KO_GDS5048_26_mouse_embryonic lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K57115335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03485
RVH421	CCLE Cell Line Gene CNV Profiles	1.0	2.06109
Lung squamous cell carcinoma_LUSC_TCGA-63-7021-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CIDEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73519
GSE241036_4_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH292	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60681
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S8-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K39227064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08138
Perturb_11712_KO_Kpna3_ERP009054	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46538
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.068
Gout	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.206
nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.093898
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L8-01A-21R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Coccidiosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
BRD-K85440939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30573
GTEX-PWOO-1326-SM-48TCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02318
establishment of localization	GO Biological Process Annotations 2015	1.0	null
PLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35146
Pancreatic islet cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.562
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table2_ChinaMAP_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE60837_0_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LRFN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63621
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11273
GSE148692,GSE148695_7_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.408
Jejunum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.144
GSE162276_4_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K23556321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7276
Diabetic ketoacidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.785
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
OXSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83604
BRD-K02788568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13225
E2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32315
upper (rostral) rhombic lip_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19328
renal glucose absorption	GO Biological Process Annotations 2023	1.0	null
GTEX-P4QT-2026-SM-3NMCJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BTK_KO_GDS1346_302_mouse_splenic B cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
immunohistochemistry	GeneRIF Biological Term Annotations	1.0	null
superficial stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19983
ligands	GeneRIF Biological Term Annotations	1.0	null
Df	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3305
hsa-miR-3190	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
levocabastine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37334
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WY7C-1126-SM-3NB3A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957811
renal absorption	GO Biological Process Annotations 2023	1.0	null
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76933
BRD-A55063801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02535
small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K65873444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34896
Proteinuria	CTD Gene-Disease Associations	1.0	1.26421
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.881
BRD-K94993773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25685
Arteriosclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.995
GTEX-QDVN-1326-SM-48TZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890982
Rectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
monoatomic anion transmembrane transport	GO Biological Process Annotations 2025	1.0	null
GTEX-WZTO-1326-SM-3NM8X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48155
cell-cell junction	GO Cellular Component Annotations 2015	1.0	null
conformation	GeneRIF Biological Term Annotations	1.0	null
GSE134029_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6878
impaired	GeneRIF Biological Term Annotations	1.0	null
loop	GeneRIF Biological Term Annotations	1.0	null
LCLC103H	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91274
Seizures	CTD Gene-Disease Associations	1.0	1.50928
BRD-K21409337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29523
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
Pulmonary hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
hypertonic dehydration	HPO Gene-Disease Associations	1.0	null
BRD-K30891382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13126
PMC10760404-NIHMS1688779-supplement-Supplementary_Table_S3.xlsx-Top_PrEC_CREB_Targets-symbol_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
vascular transport	GO Biological Process Annotations 2023	1.0	null
Premature Birth	CTD Gene-Disease Associations	1.0	1.2944
Vascular endothelial glycocalyx	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.973
Human aortic endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.81
Colonic epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.54
mode of inheritance	HPO Gene-Disease Associations	1.0	null
IPRAGLIFLOZIN	DGIdb Drug Targets 2026	1.0	1.03788
H4K20me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HEXIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56813
HMOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4093
ae2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.465
BRD-K94191869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16244
MSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74546
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843025
vascular	GeneRIF Biological Term Annotations	1.0	null
GSKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36269
GTEX-WK11-0626-SM-3NMAV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05261
H-EMC-SS	GDSC Cell Line Gene Expression Profiles	-1.0	-2.25389
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	2.81385
BRD-K90694955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11732
Perivascular astrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.532
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08723
GTEX-WYJK-0326-SM-3NMA8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Fetallung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.71121
Liver Diseases	CTD Gene-Disease Associations	1.0	1.25682
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18515
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060442
Myocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.093
CITED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57055
CHFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35015
BRD-K86792405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37954
Renal proximal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.895
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68862
IGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0311
CTSH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52113
extracellular region part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Cecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.194
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92411
DPPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78154
BRD-K00078503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09529
ATP6V1C1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00524548
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4742-01A-02R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.832145
PSRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48982
AP3M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44075
CCDC134	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91011
CW2	CCLE Cell Line Gene Expression Profiles	1.0	1.56848
GTEX-WFG8-2126-SM-3GIKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947377
Glucose intolerance	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.225
Lung Diseases	CTD Gene-Disease Associations	1.0	1.07947
bind	GeneRIF Biological Term Annotations	1.0	null
GTEX-P4PP-1826-SM-2S1NT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SLC transporter disorders	Reactome Pathways 2024	1.0	null
periventricular stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7949
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.927539
Nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.956
NHLRC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20928
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-T8EM-1626-SM-3DB7K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.056
GTEX-P4PP-1426-SM-3NM9L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23254
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2854
Perturb_9258_KO_Mr1_ERP107271	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.51718
murine	GeneRIF Biological Term Annotations	1.0	null
members	GeneRIF Biological Term Annotations	1.0	null
Hypocalcemia	CTD Gene-Disease Associations	1.0	1.01174
Hypertrophy	CTD Gene-Disease Associations	1.0	1.95375
TP63	ChEA Transcription Factor Targets	1.0	null
Gall bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.531
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_11_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
MZ2-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927273
intermediate stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26528
PMC11263707-41419_2024_6896_MOESM6_ESM.pdf-67-SIX3-AS1_SIX3	Rummagene Transcription Factor Associations 2026	1.0	null
ESO51	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAT5-23275557-MAMMARY-EPITHELIUM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBK-0226-SM-2YUMF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SARS-dORF6_0Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.55734
Stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.018
canagliflozin	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
maturity-onset diabetes of the young type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.31
Essential fructosuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0224
BRD-K87929769	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30858
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
heart_6a	HPA Tissue Sample Gene Expression Profiles	1.0	0.859368
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.882
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19838
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.098
OCRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23864
thr	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4476	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Bile ductule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.503
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_46_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-94-A4VJ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112761,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37031
Sodium/solute symporter, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K13190943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72975
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.859501
GSE164874_5_v_7_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
outside	GeneRIF Biological Term Annotations	1.0	null
GSE158632_3_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.37426
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
abnormal consumption behavior	MPO Gene-Phenotype Associations	1.0	null
Intermediate coronary syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.549
GTEX-PLZ5-0626-SM-2I5F8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27832
PURG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96995
ZIC3-20872845-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Egg yolk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.185
METRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8713
Gata-4_KO_GDS4782_329_mouse_Adult heart during pressure overload	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0718
ChIP_RNF2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Ebolavirus(EBOV)_3day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.73277
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intracellular vesicle	GO Cellular Component Annotations 2023	1.0	null
SMAD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00693857
Edema	CTD Gene-Disease Associations	1.0	1.59755
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38407
PMC10714175-mmc2.xlsx-KD_Gene_list-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
extracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
abnormal renal glucose reabsorption	MGI Mouse Phenotype Associations 2023	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Intestinal obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
protein binding	GO Molecular Function Annotations 2015	1.0	null
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table5_gnomAD_SAS_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
used	GeneRIF Biological Term Annotations	1.0	null
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.92453
PMC10933075-Table2.XLS-Gypenosides_related_target_gene-STAT3_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
r9 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02664
PMC11694450-Table_1.xlsx-MR_to_MM_at_2_DPI-Supplementary_Table_1_1_Differentially_expressed_genes_in_the_cecal_tonsil_transcriptome_in_the_M_R_group_compared_to_the_M_M_group_at_2_DPI_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K20987582	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17035
Aerial part	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.968
Testicular Leydig cell tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
metabolic process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-4755-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Forestomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.658
Epitrochlearis muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
Lung adenocarcinoma_LUAD_TCGA-55-8096-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A3I0-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.501
Gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.151
GTEX-W5WG-2426-SM-4LMI6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885415
carbohydrate transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23299
PREB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51965
liminal part of the r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88461
dorsal terminal nucleus of the accessory optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26742
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87952
BRD-K88494268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14548
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5519
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
braf	GeneRIF Biological Term Annotations	1.0	null
BRD-A77440546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1652
GSE138818_1_v_3_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118077_7_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
SPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92966
cations	GeneRIF Biological Term Annotations	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.639214
HCC2998	BioGPS Cell Line Gene Expression Profiles	1.0	1.66945
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Actomyosin contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.942
LCTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49616
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Internal secretion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
Nephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
Calprotectin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.89
iloprost-427	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
transepithelial water transport	GO Biological Process Annotations 2025	1.0	null
Pediatric Failure To Thrive	DisGeNET Gene-Disease Associations	1.0	null
BRD-K25791914	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5151
RCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78645
GTEX-T6MO-1926-SM-32QOJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
decreased body size	MPO Gene-Phenotype Associations	1.0	null
BRD-K73768826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22929
GSE166004_1_v_0_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
metal ion transport	GO Biological Process Annotations 2025	1.0	null
SLC25A51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92592
Primary somatosensory area, upper limb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00037
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Urinary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.471
PTPN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29775
nacoupled	GeneRIF Biological Term Annotations	1.0	null
BRD-K59747214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90211
Ureter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.009
newborn	GeneRIF Biological Term Annotations	1.0	null
herein	GeneRIF Biological Term Annotations	1.0	null
Perturb_11310_KO_Dicer_SRP041679	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39444
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.270909
GTEX-O5YT-1426-SM-3MJHC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01063
BRD-K92700781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10743
Epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.446
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
clinical	GeneRIF Biological Term Annotations	1.0	null
COS-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.485
Ovarian dysfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
CKAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21602
abnormal large intestine morphology	MGI Mouse Phenotype Associations 2023	1.0	null
Familial Renal Glucosuria	DisGeNET Gene-Disease Associations	1.0	null
GTEX-RUSQ-1926-SM-2TF6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
hsa-miR-579	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Septic Shock	DisGeNET Gene-Phenotype Associations	1.0	null
TCF3	ChEA Transcription Factor Targets	1.0	null
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-2.83163
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.4392
PMC10890982-13555_2024_1097_MOESM1_ESM.pdf-4-ZBTB20_ZBTB20	Rummagene Transcription Factor Associations 2026	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28462
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE57871_1_v_12_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
than	GeneRIF Biological Term Annotations	1.0	null
IRS3P_KO_GDS1219_305_mouse_brown preadipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
regulator	GeneRIF Biological Term Annotations	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.313683
GTEX-XGQ4-2526-SM-4AT57	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
ANP32D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11712
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:M04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63875
Lung adenocarcinoma_LUAD_TCGA-50-6673-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Metabolic dysfunction-associated steatohepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.684
BRD-K56253099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0042
Acetolactate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.513
TNNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92684
medial tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.81146
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925234
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.37
BRD-K17474512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10894
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K25097691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12933
nuclear membrane	GO Cellular Component Annotations 2025	1.0	null
Vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.34
GSE164874_5_v_4_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12381255-41389_2025_576_MOESM2_ESM.xlsx-Progenitor_SRCAP-1879-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
ASH2L	ChEA Transcription Factor Targets	1.0	null
FAM83E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85374
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.677
BRD-K22633587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2881
andor	GeneRIF Biological Term Annotations	1.0	null
carbohydrate transport	GO Biological Process Annotations 2023	1.0	null
PMC10794847-mmc5.xlsx-PIAS1_KD_up-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.17701
GSE210225_0_v_1_inosine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.115
DUS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20478
ES3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1143	GDSC Cell Line Gene Expression Profiles	1.0	2.19812
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.586184
ileum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.928478
localization	GO Biological Process Annotations 2015	1.0	null
DMS53	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83122
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE145215_2_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hematologic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.365
organic hydroxy compound transport	GO Biological Process Annotations 2025	1.0	null
PTTG1IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.952
hsa-miR-4465	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
CIDEC_KO_GDS3776_552_mouse_Brown and white adipose tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88584
GTEX-XOT4-1126-SM-4B66E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28955
applying	GeneRIF Biological Term Annotations	1.0	null
BRD-K86373784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4708
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
t67-small-intestine_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.33814
Medial amygdalar nucleus, posterodorsal part, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3076
CRCGN015_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34275
LS-411N	GDSC Cell Line Gene Expression Profiles	1.0	1.95518
Capillary endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.021
GTEX-SSA3-0226-SM-32QPN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
H2AC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11812
OSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87173
SDR42E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28626
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.329
PLEKHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92628
BRD-K32727528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80048
hsa-miR-1279	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.553
STRADB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24711
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.969321
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
layers	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-134	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
DPY30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28789
BRD-K77820593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27996
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.996295
kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.073204
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU407	CCLE Cell Line Gene Expression Profiles	1.0	1.57381
GTEX-X5EB-0626-SM-46MVQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4777
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43719
mantle zone of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05033
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60587
PMC2883591-pgen.1000979.s003.xls-NRSF_GENELISTS_WitOut_GeneSig_g-Supplemental_Table_3_REST	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC11868582-41423_2025_1264_MOESM4_ESM.xlsx-Table_S10-Table_S10_List_of_FICZ-induced_or_FICZ-suppressed_and_OVOL1-dependent_genes_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-96-8170-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.635
HCoV-EMC2012_7Hour_23631916_GSE45042	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.36837
aging	GAD High Level Gene-Disease Associations	1.0	0.293278
brush border	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Liver epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.056
Memory Disorders	CTD Gene-Disease Associations	1.0	1.26113
improved glucose tolerance	MPO Gene-Phenotype Associations	1.0	null
GSE232631_0_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE82032_3_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal glucose tolerance	MPO Gene-Phenotype Associations	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.891
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
vascular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069069
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_DNMT3B_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE174406_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
External plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
Brain Lower Grade Glioma_LGG_TCGA-WY-A85E-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
increased urine glucose level	MGI Mouse Phenotype Associations 2023	1.0	null
Cardiomyoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45665
YMB1	CCLE Cell Line Gene CNV Profiles	1.0	1.73878
Puberty, Precocious	CTD Gene-Disease Associations	1.0	1.03122
cervical cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.238108
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-h-Classification_of_camel_SON_basal_genes_-_transporters_SON	Rummagene Transcription Factor Associations 2026	1.0	null
KIF4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27838
Mitochondrial creatine kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.555
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3056
glucose transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
sglt1	GeneRIF Biological Term Annotations	1.0	null
Vagus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.992
Pericarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.269
GTEX-Q2AH-2026-SM-2S1PX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-R55C-1626-SM-48FEG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.292651
RH30	CCLE Cell Line Gene Expression Profiles	-1.0	-2.3144
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6032-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12093_KO_Malat1_SRP132307	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.4131
ZKSCAN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55312
Eggshell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.175
plasma membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.00547
side	GeneRIF Biological Term Annotations	1.0	null
alpha-glucoside transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
normal	GeneRIF Biological Term Annotations	1.0	null
Midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.315
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45794
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPVG-1826-SM-4B64X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84908
BRD-A71722688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52922
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872829
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4643
Necrotizing fasciitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.174
KNS60	CCLE Cell Line Gene CNV Profiles	1.0	1.6446
water transport	GO Biological Process Annotations 2025	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.705
SW1463	CCLE Cell Line Gene Expression Profiles	1.0	1.93554
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12775
Saos-2	GDSC Cell Line Gene Expression Profiles	-1.0	-2.23119
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
lower basal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.239
Supportive connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.595
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826504
Balanoposthitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.52
ZCCHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6668
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.061135
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51831
llc-pk1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.25858
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.858729
SARS-CoV MA15_Day4-PFU-10^3_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.32903
HSPA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69775
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878406
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
osmotic diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.3372
Hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
r10 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04922
CW-2	GDSC Cell Line Gene Expression Profiles	1.0	1.42931
FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
pentose transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
MIZAGLIFLOZIN	DGIdb Drug Targets 2026	1.0	3.11365
Upper respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
Lung squamous cell carcinoma_LUSC_TCGA-56-8622-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64138
ileocecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.844126
Pancreatic beta cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.515
HIVEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62972
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50591
Muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.451
NTSR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00667454
WDR18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90108
PRDM14-21183938-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
BRD-K25045770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32142
GSE181966_5_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55G-0526-SM-2TC5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44836
abnormality of fluid regulation	HPO Gene-Disease Associations	1.0	null
BRD-K73780763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3641
Basal part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.526
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12397
Optic Atrophy	DisGeNET Gene-Disease Associations	1.0	null
very-low-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.624
BRD-K01121723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44372
GSE158197_6_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173873_10_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Glutathione hydrolase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.14
Lung squamous cell carcinoma_LUSC_TCGA-33-4589-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW948	GDSC Cell Line Gene Expression Profiles	1.0	1.46293
glucose:sodium symporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE148066,GSE157787_5_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
quinpirole-456	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
identification	GeneRIF Biological Term Annotations	1.0	null
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.076
TNFAIP8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77234
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14004
SKOV3	BioGPS Cell Line Gene Expression Profiles	1.0	0.964139
transporter1	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44325
intermediate stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24813
PMC8016886-41419_2021_3630_MOESM6_ESM.xlsx-Sheet1-Table_S5_Differentially_expressed_genes_identified_between_HOXC6-low_and_HOXC6-high_expression_CRCs_using_TCGA_cohort_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
Cerebrovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
CPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00659
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38871
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1463
flavonoids	GeneRIF Biological Term Annotations	1.0	null
Cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.661
PLCB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67041
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.02386
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5261-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sepsis	CTD Gene-Disease Associations	1.0	1.01212
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.9473
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pkcdependent	GeneRIF Biological Term Annotations	1.0	null
STX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71861
intermediate stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02874
abnormal blood homeostasis	MPO Gene-Phenotype Associations	1.0	null
Myoclonic epilepsy of Lafora	Reactome Pathways 2014	1.0	null
Perturb_15188_KD_BRG1/BRM_SRP056637	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Germinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.918
Skeletal muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.159
MAP7D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88292
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8515-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU349	CCLE Cell Line Gene Expression Profiles	-1.0	-2.34108
TCF3-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
chlorogenic acid-4142	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39129
Intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.0
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Enteroendocrine precursor cell_Intestinal crypt_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
observation	GeneRIF Biological Term Annotations	1.0	null
U-87-MG	GDSC Cell Line Gene Expression Profiles	-1.0	-1.89443
GTEX-WHWD-0426-SM-3LK83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6285
periventricular stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03096
foregut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.348519
PMC12661646-dmm-18-052290-TableS9.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
represents	GeneRIF Biological Term Annotations	1.0	null
KLF2_02_29	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.90689
Perturb_9611_KO_Sufu/Spop_SRP117241	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.83498
GSE158632_3_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	Reactome Pathways 2014	1.0	null
GSE213228_2_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brush border	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Pancreatic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
Hindgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.682
hexose import across plasma membrane	GO Biological Process Annotations 2023	1.0	null
BRD-K31490008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13832
BRD-K07482874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11049
20460542-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
DRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63368
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06873
Hearing Loss	CTD Gene-Disease Associations	1.0	1.03604
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01174
NT5DC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00395262
colorectal adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.314409
STREPTOZOCIN	DGIdb Drug Targets 2026	1.0	0.135376
SPHK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99853
Insular cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.862
Muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.44
ILF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.21798
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.56946
PSME1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86704
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.840143
Rectal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.991
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63329
r8 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14515
PCBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01867
plasma membrane region	LOCATE Curated Protein Localization Annotations	1.0	null
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074995
PHF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09595
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29805
SEZ6L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28474
BRD-K79855662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40529
cell projection membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Nasopharyngeal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
decreased circulating insulin level	MPO Gene-Phenotype Associations	1.0	null
intermediate stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76532
polydatin	CTD Gene-Chemical Interactions	1.0	null
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87818
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IC-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.675
TCF3-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-NPJ8-1326-SM-3LK6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Squamous Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XGQ4-2626-SM-4AT6B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927549
bile duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.240826
Respiratory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.824
Small intestine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.133
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
metabolic acidosis	HPO Gene-Disease Associations	1.0	null
U2904	DepMap CRISPR Gene Dependency	1.0	2.3676
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	-1.0	null
gentamicin C	CTD Gene-Chemical Interactions	1.0	null
BRD-K11823863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01226
xenopus	GeneRIF Biological Term Annotations	1.0	null
Tight junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.473
Peripheral vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
Skeletal muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.227
Perturb_1393_KO_Rad9_SRP214104	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.49814
MMP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10742
GTEX-XUW1-0926-SM-4BONX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853129
Congenital sucrase-isomaltase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.968
GSE143212_0_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7881-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUDT18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65701
SNU620	CCLE Cell Line Gene Expression Profiles	1.0	1.45008
Acute Myeloid Leukemia_LAML_TCGA-AB-2866-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9656_KD_MEF2C_SRP306591	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.89867
SARS-BatSRBD_0Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.23927
time	GeneRIF Biological Term Annotations	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.870705
AIRE_KO_GDS2274_246_mouse_Medullary thymic epithelial cells (with high CD80 expression)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
myoepithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.175113
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K74391203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00867
GSE74528_0_v_1_trex2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K43911180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12369
Carcass	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.431
GTEX-U4B1-0226-SM-4DXU8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-RUSQ-1026-SM-2TF6V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Duodenal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.796
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919956
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5892-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
digestive system process	GO Biological Process Annotations 2015	1.0	null
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.977958
Prostate adenocarcinoma_PRAD_TCGA-EJ-5511-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3162
GTEX-P4QT-1826-SM-2S1NJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
sodium ion transmembrane transport	GO Biological Process Annotations 2023	1.0	null
BRD-K49635910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19166
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44N-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4539	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Squamous cell carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
largeintestine	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vulvovaginal candidiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
THEM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72522
SF539	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.863232
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848867
BRD-K68558540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39809
MAX	ENCODE Transcription Factor Targets	1.0	null
Metabolic dysfunction-associated steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.971
Contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.828
hsa-miR-4782-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
inner CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.854716
bleomycin_mus musculus_gpl1261_gse25640	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Mouth disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
Mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.994
LS 180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
renal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.179441
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60399
GSE125862_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
tinidazole-3813	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.542
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_42_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Tuber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
Extracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BRD-K14258088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24788
SBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
named	GeneRIF Biological Term Annotations	1.0	null
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K41063113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22701
Lung squamous cell carcinoma_LUSC_TCGA-66-2777-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Apical recycling endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.864
CASKIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29922
NCIH508	CCLE Cell Line Gene Expression Profiles	1.0	1.93365
TUFM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00545668
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-612	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
BRD-K73840377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44137
changes	GeneRIF Biological Term Annotations	1.0	null
GTEX-PWCY-0426-SM-48TCW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
PRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05201
apical plasma membrane	GO Cellular Component Annotations 2015	1.0	null
either	GeneRIF Biological Term Annotations	1.0	null
MSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17213
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03649
BRD-K57404319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11037
Malignant exocrine pancreas neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.096
lifethreatening	GeneRIF Biological Term Annotations	1.0	null
CCDC160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30343
superficial stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05358
SNCA_KO_GDS4153_529_mouse_cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K11846531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3675
Rectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.6
CRCGN016_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53683
GTEX-OIZI-1326-SM-3NB1B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905401
BRD-K12312755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11702
Intracellular canaliculus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.042
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.993419
KLF4-19030024-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34606
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.45458
Cation channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.708
chromosome	GeneRIF Biological Term Annotations	1.0	null
GTEX-XV7Q-1426-SM-4BRWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-POMQ-0326-SM-2I5FO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46302
small molecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Heart conduction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.77
SPI1	ENCODE Transcription Factor Targets	1.0	null
viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
CCNJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31669
Dumping syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.467
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857675
Colitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.712
because	GeneRIF Biological Term Annotations	1.0	null
GIP levels in response to oral glucose tolerance test (120 minutes)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.75229
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7411-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78676275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46422
hsa-miR-4509	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
mantle zone of r2BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14278
RNASE11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26347
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.788
Efflux pump complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.374
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kna	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
abnormal urine glucose level	MPO Gene-Phenotype Associations	1.0	null
Perturb_10228_KO_Nfat5_SRP337224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.8854
abnormal renal/urinary system physiology	MPO Gene-Phenotype Associations	1.0	null
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
ACTR1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00568659
CORO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75024
Intestinal wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.766
CUEDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17697
Perturb_3706_OE_Hif2a_SRP316426	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.3877
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.185
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.028
SNB-19 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.905
Glomerular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.681
mantle zone of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24941
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.869347
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PLK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1215
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953091
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13501
Primary somatosensory area, upper limb, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.341
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95277
Zonula adherens	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.501
Acute Myeloid Leukemia_LAML_TCGA-AB-2955-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6811
SLC44A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27022
BRD-K67426191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00295
G43417UB	GlyGen Glycosylated Proteins	1.0	null
ACER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3475
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84071
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-T5JC-1826-SM-4DM6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
PMC8218521__F2	PFOCR Pathway Figure Associations 2024	1.0	null
STAT5A-24692510-EPITHELIUM-MOUSE-MAMMARY	ChEA Transcription Factor Targets 2022	1.0	null
CHD7-19251738-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intestinal hexose absorption	GO Biological Process Annotations 2023	1.0	null
BRD-K67011787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70423
GTEX-WFG8-1626-SM-4LVMB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03737
Cervicovaginal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.122
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.71857
BRD-K67430561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42666
NP5	DepMap CRISPR Gene Dependency	1.0	3.21648
NADPH oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.717
NCIH1666	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46351
aspartate	GeneRIF Biological Term Annotations	1.0	null
B-cell lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.035
typical	GeneRIF Biological Term Annotations	1.0	null
GTEX-OIZI-0226-SM-2XCEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.26868
induction	GeneRIF Biological Term Annotations	1.0	null
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
unstirred	GeneRIF Biological Term Annotations	1.0	null
Carpel	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.433
galactose transmembrane transport	GO Biological Process Annotations 2025	1.0	null
Heart Failure	DisGeNET Gene-Disease Associations	1.0	null
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
High grade glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
Columnar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.073
GTEX-PX3G-0426-SM-48U1C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
CHO-K1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.995
nutritional deficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.109241
Colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.412
IBTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38927
GSE157594_3_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Autoimmune disease of endocrine system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.051
Sweet taste receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.243
DCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65705
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.82274
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.213
PMC9942993-pone.0281645.s002.xlsx-AR_as_non-adaptive_as_maint-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
sgk1	GeneRIF Biological Term Annotations	1.0	null
indicates	GeneRIF Biological Term Annotations	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.330827
BRD-K89014570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52462
Mitochondrial respiratory chain complex I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.601
Cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Fat pad	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.008
Paragigantocellular reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18978
Enteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.432
BRD-K69438930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00472
Lamina propria	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.614
system process	GO Biological Process Annotations 2015	1.0	null
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4371880-12885_2015_Article_1101.pdf-13-SIX2_SIX2	Rummagene Transcription Factor Associations 2026	1.0	null
BLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23343
H4K20me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
igf1r	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K62909976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2958
Gut wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.784
obtained	GeneRIF Biological Term Annotations	1.0	null
Bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.721
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MA-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.413532
EP300_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hyperlipidemias	CTD Gene-Disease Associations	1.0	1.15593
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20389
BRD-K85943445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0939
STAT5B-24692510-EPITHELIUM-MOUSE-MAMMARY	ChEA Transcription Factor Targets 2022	1.0	null
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WDR45B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61248
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OTULINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77083
TSPOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52812
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4884-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Golgi-associated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.924
Early enterocyte precursor cell_Intestinal crypt_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
Superior central nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25551
myo-inositol transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
abnormal food intake	MPO Gene-Phenotype Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G1-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A77X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05673
BT16	DepMap CRISPR Gene Dependency	1.0	3.7028
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.967223
REST_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cardiovascular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
VAPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39755
NLRP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13659
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210225_0_v_1_uba6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.78628
Kidney Chromophobe_KICH_TCGA-KL-8323-01A-21R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBR7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78125
hexose transmembrane transport	GO Biological Process Annotations 2025	1.0	null
MT-CO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78704
BRD-A47137250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59964
Hyperplasia	CTD Gene-Disease Associations	1.0	1.66253
GSE148695,GSE167281_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K10775155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12291
BRD-K88997070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44645
Nephrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
Pancreatic juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.04
Adrenocortical carcinoma_ACC_TCGA-OR-A5K4-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.858876
periventricular stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15089
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.03055
GSE132386_2_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Acute kidney tubular necrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
mainly	GeneRIF Biological Term Annotations	1.0	null
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09524
apud cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.7335
Cerebral Infarction	DisGeNET Gene-Disease Associations	1.0	null
extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69851
RPRD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72365
pentose transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
AUP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96111
GSE144115_1_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
medial part of r2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14399
BRD-K99525048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08772
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58619
DACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19977
juxtaglomerular apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.185734
1184 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
superficial stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15781
membraneembedded	GeneRIF Biological Term Annotations	1.0	null
BRD-K39824708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49738
GSE246195,GSE246305_2_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
gastrointestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111393
SKMEL28	CCLE Cell Line Gene CNV Profiles	1.0	1.95191
IMR32	DepMap CRISPR Gene Dependency	1.0	7.05718
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30498
primary	GeneRIF Biological Term Annotations	1.0	null
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
NANOG-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.64959
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81439
GSE57397,GSE57399_1_v_0_fbxw7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JRK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72508
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859673
TBCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20449
BRD-K61929684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22667
Interrenal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
smallintestine_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.34337
Phlorhizin	CTD Gene-Chemical Interactions	1.0	null
Asthma, allergic_Lung Tissue_GSE3184	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.97354
GTEX-QDVJ-0626-SM-48U1T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-X4EP-0326-SM-3P5Z6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884577
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-WI4N-0626-SM-3TW8Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38142
Ventriculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.264
BRD-K72360839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66937
neuronal	GeneRIF Biological Term Annotations	1.0	null
Cardiomyopathy	DisGeNET Gene-Disease Associations	1.0	null
PMC8881251-18_2022_4183_MOESM3_ESM.xlsx-ERM_vs_P4-DEGs_ERM_versus_P4_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
SLC2A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9788
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE241036_4_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84337
NFIC_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.911
glucoside transport	GO Biological Process Annotations 2023	1.0	null
19036130-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
GTEX-W5WG-2726-SM-4LMIC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.26076
GSE148066,GSE157787_9_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LICOGLIFLOZIN	DGIdb Drug Targets 2026	1.0	2.07576
vascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075038
HOP-62	GDSC Cell Line Gene Expression Profiles	-1.0	-1.50769
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07795
PMC9253713-mmc3.xls-sufu_KD_HCC1954_DEGs-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147056_4_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Biliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.364
TMEM259	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49761
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
overexpression	GeneRIF Biological Term Annotations	1.0	null
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.92311
PCCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82611
abdominal symptom	HPO Gene-Disease Associations	1.0	null
cis-Golgi network membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.059
SERGLIFLOZIN	DGIdb Drug Targets 2026	1.0	1.55682
GSE183251_1_v_6_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07118
cefuroxime-6088	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QEL4-0926-SM-3GAD1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26149
hsa-miR-4705	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
FAM169A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18502
Mesenteric artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.287
enteroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.752057
PMC10120965-pwac038_suppl_supplementary_table_s4.xlsx-siFOXP1-2_vs_siNC-Differentially_Expressed_Genes_DEGs_in_hCMs_upon_Silence_of_FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
Galactose	CTD Gene-Chemical Interactions	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
BRD-K21443215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77461
Epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.825
permeability	GeneRIF Biological Term Annotations	1.0	null
SW1116	GDSC Cell Line Gene Expression Profiles	1.0	1.56508
Renal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.104
HT-29	GDSC Cell Line Gene Expression Profiles	1.0	2.44512
epithelial fluid transport	GO Biological Process Annotations 2025	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.757
BRD-K46014233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02297
VRK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00398787
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.32816
ZXDC_KD_GDS5070_504_human_U937	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ZBTB40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42044
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.873172
abnormality of the urinary system physiology	HPO Gene-Disease Associations	1.0	null
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0091
Uterine disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.267
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
Lymphoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
Retinal vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.585
type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.171286
Left ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.487
HES6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33827
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Subfornical organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
trachea	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Foregut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.273
HCMEC/D3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.691
Congenital diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.237
Perturb_9563_KO_Ogt_SRP110508	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.77506
Pulmonary vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.531
UMUC1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.19743
Visceral mass	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.114
PMC12703266-gutjnl-75-1-s002.pdf-37-HES6_HES6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WYJK-1126-SM-3NM9Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0731
technique	GeneRIF Biological Term Annotations	1.0	null
LIN54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47384
GTEX-P4QT-1526-SM-3NMCT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8638-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZDHHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42194
Fundus of striatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37488
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Plant reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.286
Cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.508
nadglucose	GeneRIF Biological Term Annotations	1.0	null
Brain endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.187
Rectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.429
TLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65833
Brain microvascular endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.753
BRD-K95952081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60431
Mesangium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.71
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53085
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.247501
glucose/galactose malabsorption	OMIM Gene-Disease Associations	1.0	null
EZH2	ChEA Transcription Factor Targets	1.0	null
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
transfection	GeneRIF Biological Term Annotations	1.0	null
GSE116299_4_v_3_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH647	DepMap CRISPR Gene Dependency	1.0	2.27865
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85275
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876536
family	GeneRIF Biological Term Annotations	1.0	null
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26634
Phellem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
selective	GeneRIF Biological Term Annotations	1.0	null
BRD-K32214429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22902
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0015
ZNF254	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36342
structural	GeneRIF Biological Term Annotations	1.0	null
GTEX-OIZF-1526-SM-3MJGY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59499
premature death	MGI Mouse Phenotype Associations 2023	1.0	null
SmoothMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.879674
GTEX-WH7G-0426-SM-3NMBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15735
GSE88819_5_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24446
Starch utilization system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.298
Pulmonary Edema	CTD Gene-Disease Associations	1.0	1.08126
Weight Gain	CTD Gene-Disease Associations	1.0	1.25276
ZNF846	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5185
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.858729
cell projection part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1361
gut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.121472
BRD-K47092271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14026
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.857675
BRD-K28433349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80409
hsa-miR-26b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
NCI-H378	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH1915	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57963
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.73282
NRK-52E cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
plasma	GeneRIF Biological Term Annotations	1.0	null
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.932912
BRD-K81220870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4786
Osmotic Diarrhea	DisGeNET Gene-Disease Associations	1.0	null
Failure To Thrive	DisGeNET Gene-Disease Associations	1.0	null
Perturb_979_OE_NANOGP8_SRP065951	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.15198
decreased food intake	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-P4QT-1426-SM-3NMCX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824313
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.10216
BRD-K33005275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70186
Golgi stack	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.624
cAMP-dependent protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.756
abnormal urine homeostasis	MPO Gene-Phenotype Associations	1.0	null
single-organism transport	GO Biological Process Annotations 2015	1.0	null
ME2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00375918
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5152-01A-02R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.812
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55217
Sertoli cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.032
Head and neck cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
BRD-K17889110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54572
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.542
Meckel's diverticulum	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.744
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44757
Rhizome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.895
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.325
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.1495
KELLY	CCLE Cell Line Gene CNV Profiles	1.0	1.43984
GTEX-XAJ8-1426-SM-47JYM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844768
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
remogliflozin	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
SIMA	DepMap CRISPR Gene Dependency	1.0	2.26563
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8516-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34052
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventricular Dysfunction	CTD Gene-Disease Associations	1.0	1.19999
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61136
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64712
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09163
MARK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00586934
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B5-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.179
COPI vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.02
ventromedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15322
PMC7887593-ADVS-8-2003526-s002.xlsx-TT_AR_vs_BR-Gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870579
GTEX-X3Y1-0426-SM-3P5Z4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73499
ZFYVE21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66764
hsa-miR-4719	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Crypt	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.503
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Leydig cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.329
Cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.795
sublayer 6b of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19448
Tongue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.781
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062625
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, upper limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3587
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.695763
Neuroendocrine tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.931
lateral mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19448
Medial geniculate complex, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36122
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44866
CDK5RAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89486
carbohydrate transport	GO Biological Process Annotations 2015	1.0	null
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rin5f	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.725
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.971454
PMC8755441-mmc3.xlsx-IRF7-Up-SUZ12_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
rectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.30032
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
decreased circulating insulin level	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K52613522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5734
Perinuclear region of cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
KCNA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0060207
Amniotic fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.115
SLC25A35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82524
GSE216538_5_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
1,3-beta-D-glucan synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.566
CHD1	ENCODE Transcription Factor Targets	1.0	null
hexose transmembrane transport	GO Biological Process Annotations 2023	1.0	null
Macula densa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.543
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RU72-0326-SM-2TF5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35432
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16951
GTEX-VJYA-0926-SM-4KL1N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10255
GSE210655_3_v_0_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K53443314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68846
GTEX-UPIC-0626-SM-4IHK2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
HOPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89516
GTEX-U3ZH-0626-SM-4DXT3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06873
sucrase-isomaltase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.391
mercaptopurine-667	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pyloric cecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.555
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.931055
GSE151612_0_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.86286
Glomerular endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.758
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.19433
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.29011
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-RVPV-0226-SM-2TF6W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K49999779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60933
decreased body weight	HPO Gene-Disease Associations	1.0	null
Bone remodeling disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
BRD-K78939372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06792
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
cefotaxime-5830	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE7958	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.48527
GTEX-SE5C-1326-SM-4BRUH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Pronephros	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.391
downregulation	GeneRIF Biological Term Annotations	1.0	null
OCT4-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GRB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63242
reorganization	GeneRIF Biological Term Annotations	1.0	null
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
limbs/digits/tail phenotype	MPO Gene-Phenotype Associations	1.0	null
pentose transmembrane transport	GO Biological Process Annotations 2025	1.0	null
PMC12661646-dmm-18-052290-TableS7.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
anteroventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0435
STEAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79738
r3 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05571
hsa-miR-4650-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
BRD-K02979518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17972
Intestinal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.759
Renal glomerulus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.328
mediated	GeneRIF Biological Term Annotations	1.0	null
MARK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4655
r8 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24941
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.57541
GSE144838_7_v_5_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAKI2	DepMap CRISPR Gene Dependency	1.0	2.33514
496100364_TCx_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38481
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4634-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCH	DepMap CRISPR Gene Dependency	1.0	2.51691
hexose transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
Mitral cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
GSE162276_2_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ABCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57807
GIPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29381
Intracellular vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
change	GeneRIF Biological Term Annotations	1.0	null
JHUEM1	DepMap CRISPR Gene Dependency	1.0	3.14861
CTSF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4286
Head kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
CENPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.15437
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0846
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4644-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6510-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cefsulodin-4148	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
compartments	GeneRIF Biological Term Annotations	1.0	null
mantle zone of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41711
Arterial tortuosity syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.014
galactose:sodium symporter activity	GO Molecular Function Annotations 2025	1.0	null
Heart valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_TAZ-CAMTA1_vs_EV-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
cysteine	GeneRIF Biological Term Annotations	1.0	null
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K27067020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1593
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.23584
GSE112762,GSE112767_1_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
near	GeneRIF Biological Term Annotations	1.0	null
GSE210655_1_v_6_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SYT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83302
pellagra	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.9717
PRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82946
BRD-K64602559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31021
multi-organism process	GO Biological Process Annotations 2015	1.0	null
long femur	MPO Gene-Phenotype Associations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I7-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU478	CCLE Cell Line Gene CNV Profiles	1.0	1.4059
HDQP1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.90379
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.914292
Diarrhea	DisGeNET Gene-Phenotype Associations	1.0	null
TARBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77044
Hepatocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.934
GTEX-PW2O-0426-SM-48TCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
chloride transport	GO Biological Process Annotations 2023	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99818
colorectal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.136281
Coronary artery endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.175
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02593
malignancy	GeneRIF Biological Term Annotations	1.0	null
DUSP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44206
Nectar	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.237
INO80B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8462
Lung adenocarcinoma_LUAD_TCGA-78-7154-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.16854
discussed	GeneRIF Biological Term Annotations	1.0	null
Inflammatory diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
hsa-miR-137	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
ZNF878	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11207
PRSS22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97131
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.674
cd14	GeneRIF Biological Term Annotations	1.0	null
PMC9942993-pone.0281645.s002.xlsx-AR-as_all-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
r6 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25307
abnormality of acid-base homeostasis	HPO Gene-Disease Associations	1.0	null
MG63	CCLE Cell Line Gene CNV Profiles	-1.0	-3.08565
step	GeneRIF Biological Term Annotations	1.0	null
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.699
lubiprostone_mus musculus_gpl1261_gds4251	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XUJ4-1526-SM-4BONU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Perturb_10216_KO_Csnk1a1/Trp53_ERP021472	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.48497
NUDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79989
Diabetic Neuropathy_Sciatic Nerve_GSE11343	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.67897
GTEX-S4Z8-0126-SM-4GICC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-OXRK-1726-SM-3NB16	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922906
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8348
Perturb_6708_KO_KDM3A_SRP128505	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.4703
dglucose	GeneRIF Biological Term Annotations	1.0	null
GSE164874_5_v_8_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.45902
19658189-TableS5	GeneSigDB Published Gene Signatures	1.0	null
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.625
Ileum smooth muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
GTEX-R55E-1026-SM-2TC5S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27236
Pancreatic islet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.561
intergeniculate leaflet	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0501
NANOG-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Taste Sweet	DisGeNET Gene-Phenotype Associations	1.0	null
Prostatic Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
Anemia	CTD Gene-Disease Associations	1.0	1.38555
abnormal kidney physiology	MPO Gene-Phenotype Associations	1.0	null
methionine-importing complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.753
PER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39762
abnormal digestive system morphology	MPO Gene-Phenotype Associations	1.0	null
ZNF485	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86183
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872829
cholangiocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.346668
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.587833
BRD-K83475223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31459
R3HCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27833
BRD-K01605333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14483
predicted	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UT-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NOMO1	DepMap CRISPR Gene Dependency	1.0	2.30312
SUPT20H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74017
myoepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.262304
Golgi cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.617
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 2 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05033
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fanconi-Bickel Syndrome	DisGeNET Gene-Disease Associations	1.0	null
COLO824	DepMap CRISPR Gene Dependency	1.0	2.37484
Testicular sex cord-stromal neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
GTEX-PSDG-0626-SM-2S1OE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-RUSQ-1826-SM-2TF6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Median nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
enteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.190291
Fibrosis	CTD Gene-Disease Associations	1.0	1.50852
GTEX-OOBJ-2626-SM-2I3F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Desmosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.203
Adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.241
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65461
solute:sodium symporter activity	GO Molecular Function Annotations 2025	1.0	null
resveratrol	CTD Gene-Chemical Interactions	1.0	null
hsglt1	GeneRIF Biological Term Annotations	1.0	null
NFE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38542
GTEX-XUZC-0126-SM-4BOO6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE230744,GSE237803_0_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
G53434XO	GlyGen Glycosylated Proteins	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20U-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral hypothalamic area, tuberal part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21069
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ACSS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2007
ovary_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38407
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.22145
SPINT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01411
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05033
intermediate stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.41782
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87174
Hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.282
endothelial	GeneRIF Biological Term Annotations	1.0	null
FUT8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00493045
NCI-H1838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
YAP1-20516196-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0926-SM-48FDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84509
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.749
BRD-K32949071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67628
CCDC96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.26992
C11orf86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45681
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.90909
PMC8995879-Table_1.xlsx-exome_variants_MAF_0_01-Gencode_34_hugoSymbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Transmembrane transport of small molecules	Reactome Pathways 2014	1.0	null
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.048271
Skin disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.508
GSE112763,GSE112767_2_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
solute:cation symporter activity	GO Molecular Function Annotations 2015	1.0	null
hexose import across plasma membrane	GO Biological Process Annotations 2025	1.0	null
extracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-O5YW-1826-SM-2YUN2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-XUZC-0626-SM-4BOPG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Dilated cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
ZBTB47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00008
BRD-K55220938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90864
Scd1_DELETION_GDS4910_309_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Aortic endothelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.931
SCCPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62509
STAT1-17558387-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K04968881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26783
496100385_TCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.14833
Medial amygdalar nucleus, posterodorsal part, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39129
D-glucose transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
Apical part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.064
Catalase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.267
CRCGN017_MCF10A.WT.HP_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23765
water transport	GO Biological Process Annotations 2023	1.0	null
ZNF611	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27981
H3K27me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9518
Renal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.251
Pallidum, dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49829
conformational	GeneRIF Biological Term Annotations	1.0	null
BRD-K70735803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58733
BRD-K87343552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08977
GSE199606_6_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
rostral putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24153
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0491
Left colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.483
CIRBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18925
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
higher	GeneRIF Biological Term Annotations	1.0	null
Ebolavirus(EBOV)_1day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.77009
RNF34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28943
Heart Defects, Congenital	CTD Gene-Disease Associations	1.0	1.04721
abnormal glucose homeostasis	MGI Mouse Phenotype Associations 2023	1.0	null
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.186243
FOXA1-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
NCIH1975	CCLE Cell Line Gene CNV Profiles	1.0	1.60973
BRD-K97921950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05205
GSE166294_0_v_1_etv5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FAM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50122
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chronic Rhinosinusitis With Nasal Polyps	DisGeNET Gene-Disease Associations	1.0	null
malabsorption	GeneRIF Biological Term Annotations	1.0	null
BRD-K50271780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00692
troglitazone	CTD Gene-Chemical Interactions	1.0	null
intermediate stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22365
sodium ion transport	GO Biological Process Annotations 2025	1.0	null
small intestine	GTEx Tissue Gene Expression Profiles	1.0	1.37662
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4148-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Classic dopamine transporter deficiency syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
BRD-K90759274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57878
intestinal absorption	GO Biological Process Annotations 2023	1.0	null
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058785
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HK-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Juxtaglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.177
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.570913
K2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAMK2B	Pathway Commons Protein-Protein Interactions	1.0	null
Glomerulonephritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.306
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00112
TBC1D10C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00637767
Urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.811
NCI-H716 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.881
sodium ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Bradycardia	CTD Gene-Disease Associations	1.0	1.10734
Hartnup disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
MYC-18940864-HL60-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Mdr2_KO_GDS1990_286_mouse_Livers of 12 month old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-R55G-1226-SM-48FDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46819
cytoskeleton	GeneRIF Biological Term Annotations	1.0	null
trend	GeneRIF Biological Term Annotations	1.0	null
BRD-K55584718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98882
r9 portion of vagal motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15202
r10 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41581
intestinal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.112018
GTEX-U3ZN-0926-SM-4DXTU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883572
Congestive Heart Failure	DisGeNET Gene-Disease Associations	1.0	null
BRD-K08982277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64162
Cortical collecting duct cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.928
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4838-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LY-294002-5937	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE144838_7_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K37931645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2032
GTEX-P4QR-0426-SM-2S1NV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Pancreatic delta cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.139
failure to thrive	HPO Gene-Disease Associations	1.0	null
EM2	DepMap CRISPR Gene Dependency	1.0	2.25689
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69812
INPP5J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52184
BRD-K94771818	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01332
substrate	GeneRIF Biological Term Annotations	1.0	null
RASSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01859
GTEX-VUSG-0726-SM-3GIK1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913885
BRD-K63119190	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27187
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17332
glucose transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.09429
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cycle	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG7-1726-SM-4LVME	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24575
BRD-K22608982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42872
intestinal absorption	GO Biological Process Annotations 2025	1.0	null
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TNFRSF9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00553361
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
transport	GeneRIF Biological Term Annotations	1.0	null
GTEX-XYKS-2626-SM-4BRUT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
better	GeneRIF Biological Term Annotations	1.0	null
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.789587
requiring	GeneRIF Biological Term Annotations	1.0	null
medial part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05462
exposed	GeneRIF Biological Term Annotations	1.0	null
carrier	GeneRIF Biological Term Annotations	1.0	null
Golgi trans cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.5
hsa-miR-892b	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
holding	GeneRIF Biological Term Annotations	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.727
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868417
LRRK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00505229
PWR-1E	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OVMIU	DepMap CRISPR Gene Dependency	1.0	3.81437
Primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.386
Sodium/solute symporter, subgroup	InterPro Predicted Protein Domain Annotations	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Hypertonia	DisGeNET Gene-Disease Associations	1.0	null
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.850961
GSE142232,GSE142234_0_v_2_gcgr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REMOGLIFLOZIN	DGIdb Drug Targets 2026	1.0	1.55682
TGFBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66591
Uterine luminal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.271
GTEX-WFON-0926-SM-4LVMK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59232
Perturb_13258_KO_Pcgf3/Pcgf5_SRP115638	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.38385
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.046722
GTEX-P78B-0426-SM-2I5F5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24749
Trachea	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SNU410	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85247
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8719356-NIHMS1762846-supplement-2.xlsx-cluster_EC2_x_cluster_EC1-ID_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
sodiumdependent	GeneRIF Biological Term Annotations	1.0	null
hrs1	GeneRIF Biological Term Annotations	1.0	null
ZNF628	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40601
CRCGN008_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7744
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54042
L-6 myoblast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
carbohydrate metabolic process	GO Biological Process Annotations 2015	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2355
hydrophilic	GeneRIF Biological Term Annotations	1.0	null
GTEX-QCQG-1526-SM-48U25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRCA1_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.914292
Perturb_16833_Mut_Runx3_SRP349093	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.45301
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.584
BRD-K59772014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10061
SG in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07515
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.970466
Reticular nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56788
Colonic epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.212
PF-00562151-00-6863	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TNKS_INHIBITION_GDS5029_280_human_SW480 KRAS-mutant colorectal cancer cell line - 4hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
POR_KO_GDS1678_760_mouse_Colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Nasopharyngitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.512
CYYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.18977
BARHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43048
Celiac disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.579
NCI-H226Br cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.567
SNU46	DepMap CRISPR Gene Dependency	1.0	2.98622
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051911
GSE132759_4_v_2_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.276
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2899
BRD-K02274100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55361
NB6	DepMap CRISPR Gene Dependency	1.0	2.74014
H9c2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.244
MCCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69236
NANOG-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Vitamin metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
acidosis	HPO Gene-Disease Associations	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
NBN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00675322
Intestinal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.559
Perturb_14644_KO_PC_SRP388542	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.2591
Transmembrane transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.002
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9524
gln	GeneRIF Biological Term Annotations	1.0	null
PRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62194
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.529
Lung squamous cell carcinoma_LUSC_TCGA-60-2714-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5970-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12199
foxa2_20483781_p15_lung_lof_mouse_gpl1261_gse19204	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.184618
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
after	GeneRIF Biological Term Annotations	1.0	null
GLYATL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60813
PICK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77277
r9 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56985
synapse part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.069675
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.842
epithelial fluid transport	GO Biological Process Annotations 2023	1.0	null
NR2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47803
Brown adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.043
hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.54393
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-944	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PBK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22751
Nucleus of the optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04131
PMC12126244-jci-135-184115-s239.xlsx-Table_3_Suppl_Fig_16-Genes_down-regulated_in_SOX9_low_tumors_744_genes_SOX9	Rummagene Transcription Factor Associations 2026	1.0	null
Heart Diseases	CTD Gene-Disease Associations	1.0	1.52262
R3HDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68173
BRD-K62147342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03394
Functional gastric disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.64
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ventral posterolateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1393
GTEX-QEL4-0326-SM-3GAE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37228
Hypertrophic Cardiomyopathy	DisGeNET Gene-Disease Associations	1.0	null
GSE148692,GSE148695_7_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200673,GSE200691_2_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UNCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03863
abnormal appendicular skeleton morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K20051655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25053
D-glucose transmembrane transport	GO Biological Process Annotations 2025	1.0	null
Vulvitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
Type III protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.889
ATP5ME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77994
ChIP_NANOG_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-NFK9-1726-SM-3TW8P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Cardiovascular system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.121
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.20108
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.214
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.03877
existence	GeneRIF Biological Term Annotations	1.0	null
GSE121198,GSE129779_0_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-346	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
smallintestine_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.27005
GSE118617,GSE118619_2_v_3_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHRNB4_Deficiency_GDS2309_714_mouse_Brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-R53T-2026-SM-3GIJF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
PMC8253095-MOL2-15-1942-s005.xlsx-gene_lists-Genes_associated_with_H3K27ac-positive_sample_selective_AR_sites_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Paneth cell_Intestinal crypt_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
r8 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43257
mRNA_RXRA_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE226983_2_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Swim bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
BRD-K52083268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00429
oxidative	GeneRIF Biological Term Annotations	1.0	null
Perturb_6697_KD_LAD1_SRP117048	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.23363
Renal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.212
glycerol-3-phosphate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.034
SMARCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88841
MFE319	DepMap CRISPR Gene Dependency	1.0	4.51709
CKMT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88018
BRD-K93933512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73752
EPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94088
A431	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.584
LIVF001-007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20087
abnormal intestine morphology	MPO Gene-Phenotype Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SJ-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39395
local	GeneRIF Biological Term Annotations	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03262
dorsal subnucleus of MG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11826
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Glucagon-Like Peptide-1 Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
GSE135352_2_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Phospholamban complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.99
ZNF784	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96256
r10 part of vagal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.03252
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K62018188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68029
Brush border membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GTEX-PSDG-1626-SM-48TCQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-WHSB-1626-SM-3LK6J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
reticular formation of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03982
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858723
CHRNA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12798
macula densa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.442194
PMC10154349-41418_2023_1142_MOESM6_ESM.xlsx-Sheet1-Supplementary_data_3_Genes_positively_correlated_with_HOXC13-AS_in_skin_granular_cells_correlation_coefficients_cor_0_FDR_0_05_HOXC13	Rummagene Transcription Factor Associations 2026	1.0	null
Signal recognition particle receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.681
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
CRCGN008_HEPG2_24H:J15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07855
ACOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52265
TENT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07044
LIN7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69326
GTEX-P4QS-1726-SM-3NB1V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
further	GeneRIF Biological Term Annotations	1.0	null
SUZ12-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Basomedial amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4387
BRD-K05786443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76286
hyperparathyroidism, secondary	GAD Gene-Disease Associations	1.0	null
hsa-miR-4789-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
Autonomic nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
mitochondrial	GeneRIF Biological Term Annotations	1.0	null
BRD-K19429335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0801
ABHD17B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77244
GSE195559_8_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDVJ-1126-SM-48U1U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.581
Bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.66
EME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54334
Failure To Thrive In Infant	DisGeNET Gene-Disease Associations	1.0	null
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.66346
BRD-K58491882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23665
AP2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39062
Small intestine cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.829
SARNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59848
cotransport	GeneRIF Biological Term Annotations	1.0	null
MT-4 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
hsa-miR-105	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
COS cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.494
rhombomere 10	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51527
developmentally	GeneRIF Biological Term Annotations	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
GSE112763,GSE112767_4_v_5_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HK-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
LAGE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66501
CAV3_KO_GDS3533_17_mouse_mammary glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Hair follicle outer root sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.803
demonstrate	GeneRIF Biological Term Annotations	1.0	null
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43316
GSE135514_8_v_6_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
provide	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-324-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Fatty Liver	CTD Gene-Disease Associations	1.0	1.62335
Lung adenocarcinoma_LUAD_TCGA-55-8506-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caspasedependent	GeneRIF Biological Term Annotations	1.0	null
sevenstate	GeneRIF Biological Term Annotations	1.0	null
GTEX-Q734-1626-SM-48U1B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Lung squamous cell carcinoma_LUSC_TCGA-77-7338-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cholangiocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.385
lead	GeneRIF Biological Term Annotations	1.0	null
Basolateral cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.209
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.456809
GTEX-PWN1-1426-SM-48TDF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96017
FLI1-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SPECC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5405
lpsinduced	GeneRIF Biological Term Annotations	1.0	null
GTEX-T6MO-1126-SM-4DM5D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.277
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906739
Colorectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.428
Brain Lower Grade Glioma_LGG_TCGA-HT-7468-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS578T	CCLE Cell Line Gene CNV Profiles	1.0	1.45485
Cellular hexose transport	Reactome Pathways 2024	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
induced	GeneRIF Biological Term Annotations	1.0	null
PGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13476
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.0001
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061448
NEUROD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01735
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE148692,GSE148695_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
diarrhea	HPO Gene-Disease Associations	1.0	null
Bile	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
rs1	GeneRIF Biological Term Annotations	1.0	null
TCEA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70216
Immune System Diseases	CTD Gene-Disease Associations	1.0	1.08091
Ebolavirus(EBOV)_7day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.34164
ischemia	GeneRIF Biological Term Annotations	1.0	null
Basolateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.508
GSE112763,GSE112767_0_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abamectin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09425
GSE112761,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RHBDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5291
GTEX-WEY5-1126-SM-4LMIE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
cervical carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.083146
Immune system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
Rumen epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.41
GTEX-XQ8I-1326-SM-4BOPV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7924-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149010_0_v_4_dars2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
URI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10488
Brain Lower Grade Glioma_LGG_TCGA-FG-5962-01B-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Periglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28029
REC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44758
ZBTB38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83218
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27361
BRD-K19039329	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10986
NCKAP5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86744
MGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30094
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Acute kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
TMEM106B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7075
Exocarp	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.147
GTEX-T8EM-0626-SM-4DM62	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13501
empty	GeneRIF Biological Term Annotations	1.0	null
tlr	GeneRIF Biological Term Annotations	1.0	null
GSE210476_11_v_7_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.04636
Hypoglossal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07638
BUD31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29361
CNPY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19823
Lung adenocarcinoma_LUAD_TCGA-55-8091-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48651
Digestive juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.618
CRCGN015_MCF10A_48H:D20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29638
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
Brown-Vialetto-Van Laere syndrome 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.468
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09704
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE73628_1_v_2_igf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
LAMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65455
N4BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29388
Lateral reticular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.79915
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
assay	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5935-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
carbohydrate:monoatomic cation symporter activity	GO Molecular Function Annotations 2025	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_45_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K81288338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06207
H4C15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66766
LC4-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.53212
Malnutrition	DisGeNET Gene-Disease Associations	1.0	null
GTEX-N7MS-0826-SM-2HML4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88808
HT115	CCLE Cell Line Gene Expression Profiles	1.0	1.73989
tretinoin-6243	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96781
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.991
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.34869
GTEX-OHPM-1426-SM-3TW8Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04281
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848867
BRD-K87088675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39688
GTEX-O5YV-0626-SM-3LK64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30849
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.15274
GSE130383_2_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226355,GSE226357_1_v_0_ybx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Potassium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.709
decreased food intake	MPO Gene-Phenotype Associations	1.0	null
hsa-miR-5047	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
PMC7305081-10120_2020_1045_MOESM1_ESM.xlsx-Tab2-Mutation-MAF_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GALE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00467561
GTEX-U8XE-1926-SM-3DB98	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K78106941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05696
Digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.588
BRD-K51068004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05124
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
RPA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75851
intestinal	GeneRIF Biological Term Annotations	1.0	null
GTEX-RNOR-0826-SM-2TF5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35094
GPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96769
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1649
na2	GeneRIF Biological Term Annotations	1.0	null
reflecting	GeneRIF Biological Term Annotations	1.0	null
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.181222
SKHEP1	DepMap CRISPR Gene Dependency	1.0	2.88807
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97503
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20002
DCAF12L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12837
abnormal hindlimb morphology	MPO Gene-Phenotype Associations	1.0	null
BRD-K28140029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20191
GTEX-SNOS-0226-SM-32PLR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
ELOA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96876
DASH complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.849
Lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
FGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96266
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29G-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NMUR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88834
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.687184
GTEX-OHPK-2526-SM-3MJH9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88642
GSE196671_5_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K78748401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38418
bicuculline-4397	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
extracellular vesicular exosome	GO Cellular Component Annotations 2015	1.0	null
r8 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15899
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12025
NSMAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70665
TMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70805
Cortical amygdalar area, anterior part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11826
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	3.097
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-0826-SM-4DXU6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
plasma membrane region	GO Cellular Component Annotations 2015	1.0	null
adrenal_4a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.38407
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.694709
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.71705
mRNA_ETV3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K89931949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22404
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.935261
Roe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.758
GPR150	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60993
Globus pallidus, internal segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72527
GSE173873_10_v_13_stra8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01578
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00047
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4874-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144838_1_v_5_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K40776502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31118
GSE248858_6_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFON-2526-SM-3LK7P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.14362
Gastrointestinal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.108
adenocarcinomas	GeneRIF Biological Term Annotations	1.0	null
TBX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00308
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Anthranilate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.751
GTEX-XYKS-0226-SM-4BRW3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10286
BRD-K56415410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08039
BRD-K02630367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05329
Inflammation	CTD Gene-Disease Associations	1.0	2.27131
Death	CTD Gene-Disease Associations	1.0	1.23837
SLC27A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81204
GTEX-U8T8-2326-SM-3DB96	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Brain Lower Grade Glioma_LGG_TCGA-DU-8163-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal long bone morphology	MPO Gene-Phenotype Associations	1.0	null
Gastric juice	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.223
LS-513	GDSC Cell Line Gene Expression Profiles	1.0	1.92596
apoptosis	GeneRIF Biological Term Annotations	1.0	null
MAP1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00470667
GSE144443_5_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PCSK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37141
Inferior vena cava	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
monovalent inorganic cation transport	GO Biological Process Annotations 2015	1.0	null
Goblet cell_Intestinal crypt_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
MHHNB11	DepMap CRISPR Gene Dependency	1.0	2.48316
FAM91A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63405
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
low-density lipoprotein receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.977
Plasma membrane bounded cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
UBQLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56421
Spindle matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.655
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.72263
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XYKS-0426-SM-4BRW4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-A91823394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46859
TNS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74201
Heart Failure	CTD Gene-Disease Associations	1.0	1.58724
BRD-K89811208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45466
GSE144443_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K25646425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69333
EEF1E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30046
IGR1	DepMap CRISPR Gene Dependency	1.0	4.25827
etidronic acid-2985	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PDHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02395
GTEX-T5JW-1726-SM-3GADN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4444
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42799
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943607
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	5.68272
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100389_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32483
JHOS-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
bonds	GeneRIF Biological Term Annotations	1.0	null
SCRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88138
GSE230744,GSE237803_5_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
terminus	GeneRIF Biological Term Annotations	1.0	null
SHSY5Y	DepMap CRISPR Gene Dependency	1.0	4.25528
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K32431589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27493
SCRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25042
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7632-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
septopallidal core nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05082
Glutaminase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.07
solute:sodium symporter activity	GO Molecular Function Annotations 2023	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OF-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08697
aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089079
Gastric cecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.675
Cardiac arrest	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
TMEM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09076
GTEX-WYJK-1026-SM-3NM8W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52592
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
GSE158197_2_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
glucoside transport	GO Biological Process Annotations 2025	1.0	null
codes	GeneRIF Biological Term Annotations	1.0	null
monosaccharide transport	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7478-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S32W-1426-SM-4AD66	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
stage	GeneRIF Biological Term Annotations	1.0	null
CEP290	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96754
GRPEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06298
ZNF215	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18187
BICR31	DepMap CRISPR Gene Dependency	1.0	2.75022
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Intestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.681
TNFRSF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14957
Arrhythmias, Cardiac	CTD Gene-Disease Associations	1.0	1.07482
MMS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05468
ATP-independent citrate lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.558
End stage renal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.255
ZNF564	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84123
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83225
GTEX-PSDG-0526-SM-2S1OH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
t70-white-adipose_female_8w	MoTrPAC Rat Endurance Exercise Training	1.0	6.94385
HIF-2alpha_DEPLETION_GDS2760_643_human_Hypoxic MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lipoproteininduced	GeneRIF Biological Term Annotations	1.0	null
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.545
PAX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54122
GSK-1614235	DGIdb Drug Targets 2026	1.0	3.11365
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-591-ZNF774_ZNF774	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF648	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90654
diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.605372
IRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34185
Cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.532
DMRTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33114
TCF3-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K55779851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14307
Ischemia	CTD Gene-Disease Associations	1.0	1.51456
RBMY1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.091
GSE112760,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PSDG-0326-SM-48TCP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K68970089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14658
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.565
GTEX-XPVG-0726-SM-4B658	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04614
abnormality of the abdomen	HPO Gene-Disease Associations	1.0	null
BRD-K73296174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49811
CXorf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52222
biperiden-5279	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Ion channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.806
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C11orf68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.943
effects	GeneRIF Biological Term Annotations	1.0	null
r10 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.04955
GSE157594_3_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30647
GSE148692,GSE148695_1_v_4_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3444-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hindgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.405935
Perturb_11297_KO_Dicer_SRP041679	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
ZSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21747
Glycogen metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
Colonic adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.459
methionine-importing ABC transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.755
SAMD4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59913
Terminal web	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.522
voltage-gated calcium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.984
KCTD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33987
Pars recta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.243
PMC12496224-mmc5.xlsx-Correlation_between_GSC-Unnamed_1_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
glucoside transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Enteroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.577
Superior central nucleus raphe, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04273
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.643263
IgA immunoglobulin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.509
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26011
Acute pancreatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
HEC1B	DepMap CRISPR Gene Dependency	1.0	2.53665
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
SW1271	DepMap CRISPR Gene Dependency	1.0	2.57642
GSE196199_0_v_1_zbtb20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QEL4-1526-SM-447AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K53706972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69418
superficial stratum of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81052
KS-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47452
Gut	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
small intestine	HPA Tissue Gene Expression Profiles	1.0	1.36321
GTEX-RWS6-0326-SM-2XCAP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74159
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02593
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35908
GSE155162,GSE155169_1_v_3_buparlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Synaptic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.719
Vitamin B12 deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04843
PK59	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32045
organelle	GO Cellular Component Annotations 2015	1.0	null
glucose:sodium symporter activity	GO Molecular Function Annotations 2023	1.0	null
Small_Intestine-mature enterocyte	Tabula Sapiens Gene-Cell Associations	1.0	1.67402
residue	GeneRIF Biological Term Annotations	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.261624
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13692
Prostate adenocarcinoma_PRAD_TCGA-EJ-5521-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phenolic	GeneRIF Biological Term Annotations	1.0	null
Bile duct epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.364
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
6-phosphofructokinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.234
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCMCRM2	DepMap CRISPR Gene Dependency	1.0	2.46618
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
glut5	GeneRIF Biological Term Annotations	1.0	null
cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A196-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08792
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055855
GTEX-XOT4-0426-SM-4B66T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE212628_2_v_1_mier1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUJ4-1326-SM-4BOQ9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0619
BRD-K34980742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70218
GTEX-WHWD-0326-SM-3LK6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22809
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Intestinal epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.528
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
Medullary reticular nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60402
BRD-A57353172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02721
BRD-K08409548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31348
COX7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16021
Embryo Loss	CTD Gene-Disease Associations	1.0	1.08019
Ischemic Cardiomyopathy	DisGeNET Gene-Disease Associations	1.0	null
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907663
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.158
Plasma membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
PRDM14	ChEA Transcription Factor Targets	1.0	null
BRD-K23280067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11213
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25985
GTEX-S4Q7-0526-SM-4AD5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Adrenocortical carcinoma_ACC_TCGA-OR-A5JZ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
global	GeneRIF Biological Term Annotations	1.0	null
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.116894
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K32988853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00572
Plasma membrane bounded cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.665
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Central amygdalar nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43332
Perturb_9601_KO_Satb2_SRP307576	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BRD-K32522318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59449
NT5DC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22296
HEY	DepMap CRISPR Gene Dependency	1.0	4.04382
examines	GeneRIF Biological Term Annotations	1.0	null
intermediate stratum of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04862
markers	GeneRIF Biological Term Annotations	1.0	null
insertion	GeneRIF Biological Term Annotations	1.0	null
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01918
estimation	GeneRIF Biological Term Annotations	1.0	null
GSE199606_6_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Ost-alpha/Ost-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.888
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
pipi	GeneRIF Biological Term Annotations	1.0	null
GSE230744,GSE237803_5_v_3_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
Husk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.95
Poisoning	CTD Gene-Disease Associations	1.0	1.33494
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
BRD-K02715134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20971
Trachea	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.527
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.942179
SW948	CCLE Cell Line Gene Expression Profiles	1.0	1.38591
METTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96023
C6orf47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67016
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055158
Colonic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.603
Parotid acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S341-0726-SM-4AD5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Cell projection membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Stomach cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
carbohydrate transporter activity	GO Molecular Function Annotations 2015	1.0	null
using	GeneRIF Biological Term Annotations	1.0	null
together	GeneRIF Biological Term Annotations	1.0	null
sirna	GeneRIF Biological Term Annotations	1.0	null
identify	GeneRIF Biological Term Annotations	1.0	null
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.755
abnormality of the urinary system	HPO Gene-Disease Associations	1.0	null
BRD-K79517375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15707
MBD3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05735
Brain ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.527
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K64730761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00197
GTEX-OXRP-2426-SM-2S1NR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
496100640_PCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.52508
apical plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
intestinal hexose absorption	GO Biological Process Annotations 2025	1.0	null
Lactose intolerance	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.655
Uterine endometrial epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.984
extracellular vesicle	GO Cellular Component Annotations 2015	1.0	null
BRD-K47636083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59061
MITF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.11217
LMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65476
thioglycoside	GeneRIF Biological Term Annotations	1.0	null
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.762397
slow postnatal weight gain	MGI Mouse Phenotype Associations 2023	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40882
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
ZNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
chr22_32082985_A_AG_b38	GTEx eQTL 2025	1.0	1.14277
GTEX-SUCS-1726-SM-32PM8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
network	GeneRIF Biological Term Annotations	1.0	null
BRD-K99000702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67556
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.858723
LXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
feedback	GeneRIF Biological Term Annotations	1.0	null
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE149880_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12245139-Supplementary_material-Suppl.2-s2.xlsx-Table_S4_AR_transmission-Unnamed_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.753713
monosaccharide transmembrane transport	GO Biological Process Annotations 2023	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040251
unconventional myosin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.248578
UBLC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67879
KPNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34635
Brain Lower Grade Glioma_LGG_TCGA-HT-8114-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHORDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.808
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K58963469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01772
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_980_OE_NANOGP8_SRP065951	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.83797
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.78
STC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.112
Choroid plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.214
Lung adenocarcinoma_LUAD_TCGA-55-A494-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
KM12	BioGPS Cell Line Gene Expression Profiles	1.0	1.11279
Insulin Resistance	CTD Gene-Disease Associations	1.0	1.18751
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73P-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mutant	GeneRIF Biological Term Annotations	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
hsa-miR-331-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
YAP1-20516196-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormal intestine physiology	MGI Mouse Phenotype Associations 2023	1.0	null
alpha-glucoside transport	GO Biological Process Annotations 2025	1.0	null
sodium ion transmembrane transport	GO Biological Process Annotations 2025	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
transport across blood-brain barrier	GO Biological Process Annotations 2023	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A69B-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.4105
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Protein N-acetylglucosaminyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.772
EPLC272H	CCLE Cell Line Gene CNV Profiles	1.0	1.52965
BRD-K12306640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52378
Lymphatic system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
Metanephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.598
KMS27	DepMap CRISPR Gene Dependency	1.0	3.22703
Henles loop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.84
hsa-miR-4798-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
TSPAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04345
CYB561D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99363
Leukemia_chronicMyelogenousK-562	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.891417
ZNF436	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94366
Cranial nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.89
BRD-K80495774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63747
Short bowel syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.11
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.994461
CAMK2G	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K98065679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66009
low-density lipoprotein particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.098
Vitelline membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.042
Intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.361
SELENOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33247
Sodium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.114
ARFGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18218
BRD-K98133478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69831
Endocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.561
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Secretory diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.176
SNU1272	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81339
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13929
Rectal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.429
GTEX-QEG5-0926-SM-2TC64	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826347
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
CRCGN015_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46804
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09208
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.596
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
COL4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11009
BRD-K96567801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14915
NXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39718
Membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.971
AKAP9	Pathway Commons Protein-Protein Interactions	1.0	null
Malabsorption	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K40939137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72611
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848867
Silent myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
Saliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.536
defects	GeneRIF Biological Term Annotations	1.0	null
Mesangial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.506
BRD-K67670670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1292
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.914292
Renal proximal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	3.106
BRD-K19523047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50989
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TR-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
contribute	GeneRIF Biological Term Annotations	1.0	null
Myocarditis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
mantle zone of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22973
BRD-K66621600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30135
Small_Intestine-immature enterocyte	Tabula Sapiens Gene-Cell Associations	1.0	7.69422
GMEB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40575
BRD-K21367867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74425
BRD-K91271834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11458
GSE191015_1_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
serotonin-activated cation-selective channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.888
trans-Golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.452
Endometrial luminal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
Creatine kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.587
tanespimycin-428	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Hypoglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.96
QRICH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00697931
Abomasum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.587
diarrhea	GeneRIF Biological Term Annotations	1.0	null
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.78414
Colon carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
BRD-K45904306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02779
TBRG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47612
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
BRD-K42363982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08816
hsa-miR-4764-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
carbohydrate:monoatomic cation symporter activity	GO Molecular Function Annotations 2023	1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
GSE171837_1_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
lat1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.823
r10 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74383
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-X5EB-1626-SM-4E3IV	GTEx Tissue Sample Gene Expression Profiles	1.0	3.07002
hsa-miR-3663-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
rectal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.30032
duodenum_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.665
Cardiomegaly	CTD Gene-Disease Associations	1.0	1.11673
hsa-miR-3914	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Digestion and absorption	Reactome Pathways 2024	1.0	null
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.04761
Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DEDD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67255
secondary active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K60760423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43982
rate	GeneRIF Biological Term Annotations	1.0	null
hoct2	GeneRIF Biological Term Annotations	1.0	null
Perturb_3445_OE_Sca17_SRP248035	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.47713
Intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.45
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.921173
Non-alcoholic Fatty Liver Disease	CTD Gene-Disease Associations	1.0	1.42481
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.917078
BRD-K37971917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45069
GSE164494_0_v_2_rab22a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848867
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.41274
NPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51951
BRD-K97977764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.46049
Lung adenocarcinoma_LUAD_TCGA-05-5715-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FSP27_KO_GDS3768_514_mouse_White adipose tissue  (WAT)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Fruit	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.286
methylglucoside	CTD Gene-Chemical Interactions	1.0	null
maturity-onset diabetes of the young	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
cation-transporting ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.599
Thrombosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
ENDOU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82452
MMP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76019
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.38908
Seed coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.942
BRD-K05304510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30731
GSE130217_0_v_3_sesn2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210655_1_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CDK8_knockdown_163_GSE38061	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.05381
Prospore contractile ring	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.065
ChIP_SALL4_18804426	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
decreased body weight	MPO Gene-Phenotype Associations	1.0	null
BRD-A06158172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22727
small_intestine	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
GSE171401_1_v_0_adnp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nephrocalcinosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
Sympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.737
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94514
GTEX-OIZH-1826-SM-2YUNP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
ZNRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82246
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.857153
Carcinoma	CTD Gene-Disease Associations	1.0	1.04239
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_18Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.18644
fucose transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WD-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57484
water transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
dysfunction	GeneRIF Biological Term Annotations	1.0	null
IFNAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30471
Jugular vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.39
Pancreatic beta cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.01986
ZIC3-20872845-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K20068050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36599
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_1076_KO_Mr1_ERP107271	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.01762
GSE148066,GSE157787_5_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Blood plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.603
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2634
Grb2-Shc complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.355
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.889684
GTEX-X8HC-0226-SM-4E3K1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00512
ZNF492	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45946
Colonic adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
caused	GeneRIF Biological Term Annotations	1.0	null
BRD-K36320220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58355
Subcutaneous adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.439
oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.03873
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.1513
myosin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.080689
stress	GeneRIF Biological Term Annotations	1.0	null
GSE248858_4_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12522
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4151-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19645475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43356
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31971
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.831
appear	GeneRIF Biological Term Annotations	1.0	null
GSE113329,GSE113335_2_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4965-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE148066,GSE157787_3_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RNF2-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-A48913311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62711