association	dataset	threshold value	standardized value
EJM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
acid	GeneRIF Biological Term Annotations	1.0	null
cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.079769
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.182
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.0081
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.106877
Perturb_6736_KO_NORAD_SRP066895	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.9616
neurons	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-A4P8-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16877
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9411
GTEX-T6MN-0826-SM-32PM4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73789
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.76076
REST_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100642_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00112
GTEX-XPVG-1026-SM-4B64Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907044
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7370-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SJXC-0008-SM-4DM7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K44079161	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66673
GSE76425_0_v_10_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.844303
GTEX-Q2AI-1126-SM-48U19	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885991
GRIN2C	Pathway Commons Protein-Protein Interactions	1.0	null
Enteroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.654
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17569
Cytoplasmic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.884
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
MAP3K20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43782
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
KNS60	CCLE Cell Line Gene CNV Profiles	1.0	1.66231
CHRNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08401
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.24322
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CRCGN015_MCF10A_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.888
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14227
GSE130956_0_v_3_icaritin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PGC1alpha_DEPLETION_GDS4989_283_human_A375P melanoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
sucrase-isomaltase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.726
GTEX-SSA3-0226-SM-32QPN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76646
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
GTEX-Q734-1626-SM-48U1B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0372
cellular process	GO Biological Process Annotations 2015	1.0	null
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061104
GTEX-RWS6-2126-SM-2XCAV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.980338
GTEX-R53T-0526-SM-3GADL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17207
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25685
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.975654
GSE78199_2_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWSA-0126-SM-2XCBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CRCGN008_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81865
GTEX-SIU8-0226-SM-2XCDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04052
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.928127
BRD-K46792957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0453
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.38213
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9834
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K86995890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42671
BRD-K22229373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17634
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52497
BRD-K74568359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1465
PMC9942993-pone.0281645.s002.xlsx-AR-as_non-adaptive-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.964693
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.60608
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Lung squamous cell carcinoma_LUSC_TCGA-56-8628-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24023
AKAP9	Pathway Commons Protein-Protein Interactions	1.0	null
metal ion transport	GO Biological Process Annotations 2023	1.0	null
CRCGN015_MCF10A_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0893
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.7234
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.22931
Theca interna	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
BRD-K32476586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48179
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
MJ	DepMap CRISPR Gene Dependency	1.0	10.8407
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5699
Sodium/solute symporter	InterPro Predicted Protein Domain Annotations	1.0	null
Perturb_15238_KD_TINCR_SRP082178	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.5779
NOC3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34326
GTEX-QDVJ-0226-SM-2I5FV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52897
Perturb_12628_KD_CYGB_SRP388176	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.90747
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.3488
Rectum adenocarcinoma_READ_TCGA-F5-6464-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1807
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.841944
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
solute:sodium symporter activity	GO Molecular Function Annotations 2023	1.0	null
OVKATE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48505
artery disease	GWASdb SNP-Disease Associations	1.0	0.160835
BRD-K77465015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	7.00069
GTEX-XBED-1426-SM-4AT4G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09061
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	2.79583
GTEX-QDVN-0726-SM-4B64L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0033
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.62286
EMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90726
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70507
TPRG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21938
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.1071
CRCGN008_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9784
Sarcoma_SARC_TCGA-SI-A71O-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
SMAD3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RERFLCAD1	DepMap CRISPR Gene Dependency	1.0	2.03024
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50844
SP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63116
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.30959
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22785
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.39682
BRD-M97109212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08136
L-929 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.479
GTEX-TSE9-2226-SM-4DXUR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-XUW1-0326-SM-4BOOR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964056
cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.397423
BRD-K05846874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10982
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056315
SK-MEL-5	GDSC Cell Line Gene Expression Profiles	1.0	2.24748
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SR-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_10_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.928241
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01227
PK59	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39319
GTEX-XQ3S-0001-SM-4B64K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PMC10824666-43018_2023_699_MOESM2_ESM.xls-Suppl_Table_S4-AM-1882_AUC_vs_Gene_Expression_PRISM_Breast_and_Ovarian_Cancer_Cell_lines_n_58_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
KNOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6446
GTEX-PVOW-1026-SM-2XCF9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.36821
VDR	ChEA Transcription Factor Targets	1.0	null
GTEX-WL46-2026-SM-3LK7U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17771
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K78074905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26224
BRD-K37014934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0605
GTEX-QEL4-0526-SM-3GIJ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Lung adenocarcinoma_LUAD_TCGA-55-6969-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Serotonergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.761
PMC9942993-pone.0281645.s002.xlsx-AR-as_all-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K98513899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40435
centromedian nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.932962
apical junction complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.340017
sugars	GeneRIF Biological Term Annotations	1.0	null
VCAP	DepMap CRISPR Gene Dependency	1.0	6.59827
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37462
chr22_32365481_G_A_b38	GTEx eQTL 2025	1.0	1.6427
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-U3ZH-0002-SM-3NMDD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.635013
BL-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE233679_6_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
renal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.744214
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GSE121198,GSE129779_3_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.90728
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.63
Lung adenocarcinoma_LUAD_TCGA-50-6590-01A-12R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEC265	CCLE Cell Line Gene Expression Profiles	1.0	1.51354
Small Cell Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A6RY-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spectinomycin-4773	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K18197334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00804
intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
EID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60133
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.724
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5165
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CRCGN017_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1537
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.287092
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95538
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053759
single-organism localization	GO Biological Process Annotations 2015	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1883
BRD-K75038426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41764
PHOX2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96229
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELK3_ELK3	Rummagene Transcription Factor Associations 2026	1.0	null
SOTAGLIFLOZIN	DGIdb Drug Targets 2026	1.0	1.47033
Brain - Hypothalamus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.739322
GSE148514_0_v_1_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12143321-mmc3.xlsx-Sheet1-NR3C2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
HS578T	CCLE Cell Line Gene CNV Profiles	1.0	1.46783
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5336
BRD-K21124684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06445
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
IGF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66289
ZDBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63027
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
BRD-K63111122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40447
GTEX-RUSQ-0626-SM-2TF5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11539
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.34972
AR	ChEA Transcription Factor Targets	1.0	null
COLO800	DepMap CRISPR Gene Dependency	1.0	7.69882
ZR751	CCLE Cell Line Gene CNV Profiles	1.0	1.33603
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043573
BRD-K97106314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09517
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H5-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PDE6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24501
sglt1	GeneRIF Biological Term Annotations	1.0	null
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.07461
CRCGN015_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.97725
GTEX-V955-0926-SM-4JBJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-X5EB-0426-SM-46MVY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32801
GSE213588_8_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
protophloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.194192
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.850741
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.993518
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06728
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.622575
GHITM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3342
Amino acid transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.901
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.60123
KMS20	DepMap CRISPR Gene Dependency	1.0	2.84792
COLO849	CCLE Cell Line Gene Expression Profiles	1.0	1.64089
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0458
BRD-K05002317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16429
Renal proximal tubule epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
Sodium/solute symporter, subgroup	InterPro Predicted Protein Domain Annotations	1.0	null
Renal tubular transport disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.466
SNU423	DepMap CRISPR Gene Dependency	1.0	2.58371
GTEX-TKQ2-0826-SM-33HB6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.923135
BRD-K25337138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00523
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071136
CBFA2T2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22251
GTEX-REY6-0326-SM-2TF5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8558
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0965
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053274
CMK	CCLE Cell Line Gene Expression Profiles	-1.0	-2.13529
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
oseltamivir-phosphate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75307
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.15659
GTEX-S341-0826-SM-4AD73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918472
Kidney Chromophobe_KICH_TCGA-KN-8424-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
KPNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67045
placenta_3a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851705
VDAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58216
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.57383
muscle	GeneRIF Biological Term Annotations	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Superior mesenteric vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.853
GTEX-Q734-0626-SM-2I3EF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3964
carbohydrate:monoatomic cation symporter activity	GO Molecular Function Annotations 2025	1.0	null
nod2_21335489_hek293_lof_human_gpl570_gds4416	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.013292
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
outer plexiform zone in extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.892373
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06624
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-PLZ6-0426-SM-2I5FG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21127
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.946979
Lung adenocarcinoma_LUAD_TCGA-55-6981-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG7-1726-SM-4LVME	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17513
BRD-K23316938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10977
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6041
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.01084
CAMK2A	Pathway Commons Protein-Protein Interactions	1.0	null
naglucose	GeneRIF Biological Term Annotations	1.0	null
Theca folliculi	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.659
BRD-K99119142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.60829
BRD-K98020844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01008
juxtaglomerular apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.187393
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PIEZO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33007
BRD-K61087440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11525
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210885_3_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GRIN2B	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intestinal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.129521
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
YM-543	DGIdb Drug Targets 2026	1.0	2.2055
TAGLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64263
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.865728
BRD-K84099887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3685
BRD-K58028568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.92032
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.552
PPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99371
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XC-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.355
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K86192746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28114
GTEX-QDT8-0326-SM-32PL1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841181
GTEX-RU1J-0126-SM-2TF6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00453
WM115	CCLE Cell Line Gene Expression Profiles	1.0	1.35539
Prostate adenocarcinoma_PRAD_TCGA-EJ-7792-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61855
DCBLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43572
APH1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7457
T3M10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65499
adrenal cortex disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.12476
COLO-800	GDSC Cell Line Gene Expression Profiles	1.0	1.5267
HIPK2_knockdown_106_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.67615
Renal proximal tubule epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.801
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Perturb_15515_KD_E2F2_SRP314859	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.5598
PMC6451636-NIHMS79910-supplement-Supplementary_table_1.xlsx-MAF_1_not_in_control_exomes-Gene_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
apical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.917177
Lung adenocarcinoma_LUAD_TCGA-86-A4P7-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KELLY	CCLE Cell Line Gene CNV Profiles	1.0	1.45232
SECISBP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37195
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78017
GTEX-W5WG-1326-SM-4LMI9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932693
HDQP1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5086
lung_3e	HPA Tissue Sample Gene Expression Profiles	1.0	0.9096
BRD-K67460571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12826
ZNF416	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71222
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81746
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05623
metaphloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.196569
BRD-K54712090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50188
GSE225982_1_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	-1.0	null
chr22_32430735_G_A_b38	GTEx eQTL 2025	1.0	1.6649
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.77013
VDR-23401126-LCL-AND-THP1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K13534347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59856
PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
RT4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC4407272-elife06857s002.xlsx-Hermes_BRG1-MITF_ComDown-List-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31283
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.76878
RNF145	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07513
GTEX-OXRO-0226-SM-3LK6F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858303
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K93374700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43852
valproic acid-629	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K12613826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23434
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-UPK5-2126-SM-4JBJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2218
BRD-K12431811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85983
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TW-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIRMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2249
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K98161738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.9099
GTEX-WEY5-0001-SM-3P61Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.2356
BRD-K72224143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.2423
Loneliness (multivariate analysis)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
placenta_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
Glucose transporter complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.558
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.852529
496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.56697
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69987
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Basolateral cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.332
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4604
MAPKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60952
H3K27me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-RU1J-0008-SM-46MV9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
SOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25893
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.80898
BRD-K26018295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00107
GSE135312_1_v_2_bmpr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AKNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14372
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040178
CRCGN015_MCF10A_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16025
Perturb_4500_KO_zc3h12a_DRP003625	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds	Reactome Pathways 2014	1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03796
TRAPPC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58303
GTEX-X5EB-0726-SM-46MVR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15699
BRD-K93023309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75725
ATMIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79261
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.51003
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
SUM 159PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.957469
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08876
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
FAM104B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72584
WM2664	CCLE Cell Line Gene Expression Profiles	1.0	1.57926
PMC9942993-pone.0281645.s002.xlsx-AR-as_non-adaptive-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KDM5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34746
BRD-K93774122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56208
BRD-K01699883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12391
BRD-K73830970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63764
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Organism form	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
pulmonary edema	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.52729
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.35049
migraine with aura	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.430768
GTEX-XXEK-1026-SM-4BRUW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912622
GTEX-XUW1-1026-SM-4BONY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28337
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.917095
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11528
NCIH1915	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72358
BRD-K37308886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37623
portal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.502357
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922824
NTMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33844
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04145
H3K27me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.726507
BRD-K03886176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22549
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1381
alphaglucosidases	GeneRIF Biological Term Annotations	1.0	null
GTEX-RU72-1126-SM-2TF6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855016
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05921
Enteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.721
BRD-K41915268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.47771
GTEX-S7SF-1326-SM-4AD4P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847986
PACADD188	DepMap CRISPR Gene Dependency	1.0	2.37691
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33233
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.91963
SKMEL2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60419
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K72936860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08258
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.05255
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
ATIGLIFLOZIN	DGIdb Drug Targets 2026	1.0	4.411
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HE-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.186
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.49444
GSE210093_3_v_2_taf15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
MDAMB453	CCLE Cell Line Gene CNV Profiles	1.0	1.37692
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_47_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UJHI-0726-SM-3DB92	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50949
EMPAGLIFLOZIN	DGIdb Drug Targets 2026	1.0	0.8822
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.852529
Lung squamous cell carcinoma_LUSC_TCGA-98-8022-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Epstein-Barr Virus_Akata BL clone-4hr starve_None_GSE19761	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.61811
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GSE148692,GSE148695_1_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2104
Mewo	GDSC Cell Line Gene Expression Profiles	1.0	1.63803
small intestine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.191368
possible	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.23589
hk-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.721166
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.995396
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25079
BRD-K24124047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42662
GTEX-WK11-2426-SM-3NMAA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83291
smallintestine_4a	HPA Tissue Sample Gene Expression Profiles	1.0	2.5918
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4347-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
retinal vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.102895
PMC4407272-elife06857s002.xlsx-Hermes_BRG1-MITF_ComDown-List-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-PSDG-0726-SM-2I5FN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03613
Skeletal muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.94
GTEX-RU72-1026-SM-46MUG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5063
NCIH1975	CCLE Cell Line Gene CNV Profiles	1.0	1.62779
BRD-K06486611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8836
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JL-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZQ-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
GTEX-XGQ4-1326-SM-4GIDU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56322
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06138
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Pancreatic alpha cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.263
GTEX-UJMC-0726-SM-3GADX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08749
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K89122173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43039
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
MAP4K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0307
MANEAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23499
GTEX-QLQ7-1826-SM-2S1R5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898288
BRD-K27401646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78356
RHPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17686
Renal proximal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.126074
serotonin-activated cation-selective channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.746
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.9435
striatum_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12801
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZFYVE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6671
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.656837
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.9931
QARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09249
BRD-K65361030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3318
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.656837
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K25426017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21029
BRD-K45893504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50699
Acute Myeloid Leukemia_LAML_TCGA-AB-2837-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.464
GLUFOSFAMIDE	DGIdb Drug Targets 2026	1.0	0.551375
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.868937
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
TMEM242	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12836
BRD-K48171978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44939
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	1.0	2.93179
GSE213588_8_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AR-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.55667
REST_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24446
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8416
NCBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63863
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.472704
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K83045795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66963
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Jun	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.4566
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4011
GTEX-S4UY-1226-SM-4AD51	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17685
t64-ovaries_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	4.6477
HINFP	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CERS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18953
BRD-K65250438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16001
BRD-K91620436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41012
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.698
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40708
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.899
GTEX-TSE9-2626-SM-4DXV2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852274
PCID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13886
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5110-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
D-glucose:sodium symporter activity	GO Molecular Function Annotations 2025	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
jejunum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.385143
WDR18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3355
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1071
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7732
WM983B	CCLE Cell Line Gene Expression Profiles	1.0	1.60687
DEL	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50803
extracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.173273
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.43005
GTEX-RVPV-1226-SM-2TF73	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05695
TOV112D	DepMap CRISPR Gene Dependency	1.0	2.91181
GTEX-RUSQ-1026-SM-2TF6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859051
GTEX-XUJ4-1526-SM-4BONU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909565
adrenal gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.111272
PEX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92462
GTEX-XQ8I-2326-SM-4BOQC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.837725
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ADAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69398
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.927342
18722011-SuppTable2n	GeneSigDB Published Gene Signatures	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28311
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.739
GTEX-WRHU-0926-SM-4E3IG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75166
rostral group of intralaminar nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14339
small intestine	HPA Tissue Gene Expression Profiles	1.0	1.53799
GSE139966_4_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5846
PMC4595011-pgen.1005555.s001.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Renal outer medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.743
CRCGN009_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09685
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A7DS-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUPT5H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.1279
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OW-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUPT4	DepMap CRISPR Gene Dependency	1.0	6.18306
BRD-K89992188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40745
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42635
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K76087404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3105
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.804
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0907
CRCGN015_MCF10A_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.88225
LCLC-103H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.87466
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13831
BRD-K61924932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71064
IGR-1	GDSC Cell Line Gene Expression Profiles	1.0	2.67738
UACC-257	GDSC Cell Line Gene Expression Profiles	1.0	1.75282
BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K08527280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46287
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042897
Fanconi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4908-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16969
CRCGN008_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0127
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0772
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80416
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QY-01A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21417
BRD-A30962679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47777
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01891
sieve tube	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.92291
Lung squamous cell carcinoma_LUSC_TCGA-51-4079-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100442_PCx_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37133
WM-266-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30305
BRD-K62229896	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06222
BRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97884
GTEX-OIZH-0526-SM-2HMKV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882027
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44021
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93218
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9609
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
ZNF772	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16742
BRD-K45380779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32263
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.46511
type	GeneRIF Biological Term Annotations	1.0	null
GTEX-X261-1026-SM-3NMDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59772
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.783
NCIH2228	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38461
GTEX-WFON-1126-SM-4LVMA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
ATP-independent citrate lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.999
GTEx Brain 20-29 vs 30-39	GTEx Tissue-Specific Aging Signatures	1.0	6.00557
BRD-K54931539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10902
GTEX-PX3G-2626-SM-2I3EG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03519
outer SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39067
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4344-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3647
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35949
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855889
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5803
TUHR10TKB	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.933227
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.952023
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX3-fromNode_SOX3	Rummagene Transcription Factor Associations 2026	1.0	null
SRXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17285
bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.178682
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8892
TMEM177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72514
GTEX-QESD-0626-SM-2I5G4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979278
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.12636
CAL51	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35922
IZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.955644
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Liver hepatocellular carcinoma_LIHC_TCGA-5R-AA1D-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18525
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z3-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBJ-0526-SM-48TDK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09377
Lung squamous cell carcinoma_LUSC_TCGA-56-8626-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE94849_1_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PWCY-2226-SM-2S1OP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
SREBF1	JASPAR Predicted Transcription Factor Targets	1.0	null
RPUSD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13238
Perturb_2975_KO_7p15.2_SRP107176	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.66213
ALX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43293
GTEX-OOBJ-2626-SM-2I3F6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39808
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77347
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZE-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of brain morphology	GWASdb SNP-Phenotype Associations	1.0	0.1914
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12367
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.13265
Lung squamous cell carcinoma_LUSC_TCGA-94-8491-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.71956
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EK-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.960979
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.850433
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1278
HSPE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25621
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PPP1R10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44004
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58432
BRD-K04873321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98018
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96664
BRD-K27881453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1871
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.451042
GTEX-VJYA-0426-SM-3GIJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54272
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6868-01B-12R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RS4-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2259
GSE210885_5_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.3135
GTEX-Q2AG-0826-SM-2HMKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30567
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
leaf sheath	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.89902
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.931512
GSE240386,GSE242143_1_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SBNO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37814
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K78015078	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17362
BRD-K81669067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1946
BRD-K63270352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08663
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30391
Cellular hexose transport	Reactome Pathways 2024	1.0	null
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38638
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58679
GTEX-RU72-0126-SM-2TF6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01065
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19963
renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.61559
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6047
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14798
BRD-K06408981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.47195
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.187
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.039187
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
CRCGN016_MCF10A.TP53.M_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0335
42-MG-BA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Orphan transporters	Reactome Pathways 2014	1.0	null
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.45274
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96664
CRCGN013_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78992
ES-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9562
Vastus lateralis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.919
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049871
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC-33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PTPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39246
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54844
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K51270604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5892
exercise	GeneRIF Biological Term Annotations	1.0	null
outer CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08738
Metabolic acidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.251
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.905
GTEX-XXEK-0008-SM-4BRW7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
RVH-421	GDSC Cell Line Gene Expression Profiles	1.0	1.54777
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4759
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
cerebral ischemia	GWASdb SNP-Phenotype Associations	1.0	0.451464
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Intracranial arterial disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
496100602_TCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05443
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28747
hypokalemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.20658
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z6-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
FTO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49723
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36833
Chronic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K19315592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00743
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Brain disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
ZNF229	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97847
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
IKBKE_knockdown_97_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.72703
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.10346
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Taste bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.27
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-OXRL-0526-SM-2I3EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46239
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.466111
COLO 679	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.53645
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.912407
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
HUO-3N1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PIP5KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7069
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GOTO	GDSC Cell Line Gene Expression Profiles	-1.0	-1.80052
Dehydrodolichyl diphosphate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.748
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
Cell projection membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.957
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NA-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6648
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.28631
SNU410	CCLE Cell Line Gene CNV Profiles	-1.0	-2.17261
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.72702
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.838288
BRD-K60828552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51431
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CRCGN016_MCF10A.WT.HP_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01908
NCIH292	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76184
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.49585
CRCGN016_MCF10A.WT.HP_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39229
Acute Myeloid Leukemia_LAML_TCGA-AB-2880-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15878
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07385
CDC25A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3536
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6027-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletal	GeneRIF Biological Term Annotations	1.0	null
GTEX-WRHU-0326-SM-3MJFY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935993
TRA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51657
DDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48121
GTEX-W5X1-0526-SM-3GILH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5233
sclera	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.222699
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.13723
MYCN-21190229-SHEP-21N-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
extracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.115583
BRD-K53319404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34011
GTEX-U4B1-0526-SM-4DXTK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02632
solute:sodium symporter activity	GO Molecular Function Annotations 2025	1.0	null
BRD-K51490301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25101
BRD-K01715539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90685
RELB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10357
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.082182
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.29492
BRD-K10398797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.68966
HOXC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84266
instead	GeneRIF Biological Term Annotations	1.0	null
hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.543542
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K54872884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38844
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
abnormality of cerebral artery	GWASdb SNP-Phenotype Associations	1.0	0.351763
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.5344
MED26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58526
BRD-K00793226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06719
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053596
RAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12325
blood	GTEx Tissue Gene Expression Profiles	-1.0	-2.09212
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851705
metal ion transport	GO Biological Process Annotations 2025	1.0	null
RCH-ACV	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN009_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.402
PECAPJ41CLONED2	DepMap CRISPR Gene Dependency	1.0	5.99594
CANAGLIFLOZIN	DGIdb Drug Targets 2026	1.0	1.47033
GTEX-X4EP-0526-SM-3P5YW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924082
AKAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38331
impaired renal function disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.189244
Insulin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.968
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1562
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22481
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.89698
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETS1_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.923227
Septicemia	DisGeNET Gene-Disease Associations	1.0	null
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20136
NIF3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58426
Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
renal tubular transport disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.596402
single-organism transport	GO Biological Process Annotations 2015	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6342
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57859
MAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89601
NCI-H2596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32513
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.927869
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28024
GTEX-RM2N-1826-SM-2TF5B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8CQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
subapical complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.752716
ureteral disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.215653
Adrenocortical carcinoma_ACC_TCGA-OR-A5LO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873099
BRD-K68683482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98263
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0403
BRD-K60823407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02066
CRCGN015_MCF10A_48H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.28636
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1206
CRCGN014_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14663
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32172
GSE148692,GSE148695_7_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-W5X1-0426-SM-3GILB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07306
TPSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79535
TRIM56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40932
BRD-K16074065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13087
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80298
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CEBPG_CEBPG	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6156-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.70199
BRD-K42526449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23923
CGTH-W-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.03745
Diabetic ketoacidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.343
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.5336
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74136
BRD-K49525275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14836
BRD-K59389251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05935
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.77934
496100599_TCx_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.84011
LAMTOR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04416
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HPAC	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63252
GTEX-P4QT-2026-SM-3NMCJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09745
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.4807
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33465
PANC-04-03	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MPST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16066
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26012
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.247719
STK38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83814
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96664
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74581
Enterocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.854
GET3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76524
sugar	GeneRIF Biological Term Annotations	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.952524
BRD-K75999096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91493
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-XMD1-0826-SM-4AT52	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995044
Cerebrovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
BRD-K44103530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28339
BRD-K02866760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49622
BCOR-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.793
GTEX-S7SF-1826-SM-3K2AD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834727
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32513
BRD-K21897482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23116
BRD-K82107433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23738
KMS21BM	CCLE Cell Line Gene CNV Profiles	1.0	1.54692
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4338-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesenteric vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.003
GTEX-UTHO-0726-SM-3GAEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K01772946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51795
Neuromuscular junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.463
BRD-K40876208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04772
RARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30507
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.941134
GTEX-S7SE-0826-SM-4AT4D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03417
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OIZG-0526-SM-2HMLF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887839
GSE196671_6_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PGR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65799
BRD-K24848743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22352
Myoclonic epilepsy of Lafora	Reactome Pathways 2014	1.0	null
NCI-H1437	GDSC Cell Line Gene Expression Profiles	-1.0	-1.41879
GTEX-WRHU-0726-SM-3MJFL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86239
FBXO48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08427
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-Q2AH-0726-SM-2I3EA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15137
Median nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.975
BRD-K50721666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18263
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K26130452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25609
Intracranial aneurysm	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
SMAD4-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.464174
CRCGN008_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0444
GTEX-S7SE-0926-SM-2XCD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33795
BRD-K40018788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27498
RFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72842
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.834375
Lung squamous cell carcinoma_LUSC_TCGA-66-2768-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJYA-0926-SM-4KL1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69655
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS-STRESS	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Renal proximal tubule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.28
Submucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.305
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
functions	GeneRIF Biological Term Annotations	1.0	null
CAL148	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85713
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.865475
Caco-2/TC7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.604
ACTN2	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K24479270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49444
GTEX-XXEK-0426-SM-4BRVW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-SIU8-0826-SM-2XCDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974891
Lung adenocarcinoma_LUAD_TCGA-55-6970-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DKC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62625
Small_Intestine-enterocyte of epithelium of small intestine	Tabula Sapiens Gene-Cell Associations	1.0	5.59868
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SIU7-1626-SM-4BRUK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885939
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.46766
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70057550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46256
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.69205
BRD-K56870772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13554
parahippocampal gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.88917
BRD-K20203758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18944
SERPINB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98646
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6595-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CNOT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32855
Perturb_4854_KD_ZEB2_SRP059197	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	12.7443
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7377
GSE251992_1_v_0_saracatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0418
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35503
WIPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67623
SLC7A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77075
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	1.40231
PMC4595011-pgen.1005555.s002.xlsx-MITF_DOWN_in_30kb-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
COLO205	BioGPS Cell Line Gene Expression Profiles	1.0	0.832074
NOTCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45974
GTEX-NFK9-1026-SM-2HMK1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2678
stratum oriens of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.919786
BRD-K81082554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37978
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.54034
GOLGA6L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69426
GTEX-PWN1-2626-SM-2I3FH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42253
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.96728
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Infundibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.03865
TRAIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46739
amygdalohippocampal transition zone, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.88449
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Supplementary_Figure_15l-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
ABL1_knockdown_100_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.53694
vascular bundle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.756604
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.89813
H3K27me3_CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ut1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.968606
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.213291
SP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8479
GTEX-P4PQ-2626-SM-33HC9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14199
dorsal lateral geniculate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.868107
Perturb_9711_KD_SMARCB1_SRP279089	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.51379
CRCGN011_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6573
SNU1076	DepMap CRISPR Gene Dependency	1.0	5.44275
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5523
GTEX-NPJ7-0008-SM-4E3JS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34747
GTEX-W5WG-2226-SM-4LMI3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K36099605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3494
BRD-K77214724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04964
GTEX-P4PP-3026-SM-3P61O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16143
BRD-K09144377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95799
CRCGN013_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66684
vascular tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.592444
GTEX-RTLS-2426-SM-46MUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11805
GTEX-RU72-2626-SM-4GIE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24275
Gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PSMA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45172
BRD-K94637240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67896
Ileum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.722
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6612
stele	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.775249
TUB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03431
BRD-K48853765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50876
CRCGN016_MCF10A.TP53.M_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48455
PMC7495487-41598_2020_71030_MOESM2_ESM.xlsx-Sheet1-NR1A1_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Metabolism	Reactome Pathways 2014	1.0	null
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19455
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-RWS6-0008-SM-47JYV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.74178
Brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.219
kidney disease	GWASdb SNP-Disease Associations	1.0	1.14065
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.915352
MITF	ChEA Transcription Factor Targets	1.0	null
SKMEL28	CCLE Cell Line Gene CNV Profiles	1.0	1.96298
cation transport	GO Biological Process Annotations 2015	1.0	null
LLC-PK1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.162
Primary hematopoietic stem cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.826237
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.970922
BRD-K39709536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0904
MSTO-211H	GDSC Cell Line Gene Expression Profiles	-1.0	-1.6218
PMC6879454-Data_Sheet_1.xlsx-AA_in_vitro-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2163
Cervix - Ectocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	1.47015
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07568
COLO849	CCLE Cell Line Gene CNV Profiles	1.0	1.76113
BRD-K87722624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50386
NICN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71873
MASTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43213
ZNF44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08108
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
duodenal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.237216
CL11	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68564
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7182
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.673518
Perturb_4852_KD_ZNF503_SRP059197	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.86255
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RN64-0626-SM-2TC5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37838
NOTCH_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
BRD-K24499562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11227
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.0884
GTEX-X638-0003-SM-47JZ1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
imino	GeneRIF Biological Term Annotations	1.0	null
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.92404
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RIC8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88613
BRD-K39342915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38986
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
THAP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56036
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
MYCN-21190229-SHEP-21N-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GRIN1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN013_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11192
BRD-K80239721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86986
BRD-K02190643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09975
PSMB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63692
JIMT-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.918893
BRD-K01960204	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37658
COMMD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15643
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.250389
Inward rectifying potassium channel	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.819
tissues	GeneRIF Biological Term Annotations	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Alimentary canal	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.751
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EY-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47707
other	GeneRIF Biological Term Annotations	1.0	null
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07225
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11497
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
KDM5A	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.57436
MED1_OE_GDS4846_11_human_LNCaP prostate cancer cell	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
EPLC272H	CCLE Cell Line Gene CNV Profiles	1.0	1.54582
hsa-miR-664	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-OHPM-0126-SM-2YUN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
RPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12909
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.3786
Small intestine	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06044
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39228
I-cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
GTEX-P78B-0726-SM-2S1O2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10178
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05454
duodenum_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.73257
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Hydranencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
CBLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3936
GSE112714_2_v_3_ctnnb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-3926-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063321
MAGOH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85112
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.09755
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3224
artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055945
MELHO	CCLE Cell Line Gene Expression Profiles	1.0	1.84278
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.08083
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.491
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903311
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.593
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.876307
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851705
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5231-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C80	DepMap CRISPR Gene Dependency	1.0	2.13434
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16515
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6682
Prostate adenocarcinoma_PRAD_TCGA-2A-A8VT-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4267
BRD-K11307720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03162
HOPX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5707
intestinal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.232881
CGB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10929
LRRC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23599
BRD-A01717111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14924
GTEX-QDT8-0226-SM-32PL4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837112
heart_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
ureteral obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.258417
BRD-K35848924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28694
BRD-K29331543	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56618
GM97	BioGPS Cell Line Gene Expression Profiles	1.0	1.40371
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.291365
retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057649
GTEX-XV7Q-1426-SM-4BRWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.915409
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050449
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05315
COLO678	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99415
SH4	CCLE Cell Line Gene Expression Profiles	1.0	1.53039
HLCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92098
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.984991
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
basolateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.39832
Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1055
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14349
DDX47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02299
sodium ion transport	GO Biological Process Annotations 2015	1.0	null
BRD-K80098154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89371
LAGE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2714
GTEX-W5WG-2426-SM-4LMI6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GSE183994_3_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054718
ZNF771	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84775
DEOC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23113
connecting tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.193558
organic substance transport	GO Biological Process Annotations 2015	1.0	null
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.399492
ELMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64073
Uterine Carcinosarcoma_UCS_TCGA-N8-A56S-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RU72-0626-SM-46MUI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921546
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46608
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
MONO-MAC-6	GDSC Cell Line Gene Expression Profiles	-1.0	-1.89661
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05623
BRD-K56916066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1219
hsa-miR-576-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GSE245270_2_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
G361	CCLE Cell Line Gene Expression Profiles	1.0	1.40339
TRIM33_KD_GDS4071_449_human_HMEC-TR mammary epithelial cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08065
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.363
NUP205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30329
BRD-K42789863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26546
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
K029AX	CCLE Cell Line Gene Expression Profiles	1.0	1.45156
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.474
G118	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.04576
Renal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.26
GTEX-UPIC-0826-SM-3GADQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997625
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26456
CRCGN009_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.68691
Kidney Chromophobe_KICH_TCGA-KL-8333-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.92656
PLK3_knockdown_121_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.65485
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.413912
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.423818
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	2.81652
BRD-K72993421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88523
H3K27me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
duodenum_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.35974
Lung squamous cell carcinoma_LUSC_TCGA-56-8503-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU668	DepMap CRISPR Gene Dependency	1.0	2.3495
inner CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.912936
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K34086616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14862
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-RWS6-0626-SM-2XCAS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988001
BRD-K49742819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28198
RH30	CCLE Cell Line Gene Expression Profiles	-1.0	-2.33038
glucose transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
BRD-K00233837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19636
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01991
CALML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66297
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4961-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K04613932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35413
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.887329
YMB1	CCLE Cell Line Gene CNV Profiles	1.0	1.75515
GTEX-POMQ-1226-SM-3P61F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04109
ATP5PF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68244
BRD-K57365604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05106
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7823
BRD-A05635986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18048
LIVF001-023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18485
amygdaloid complex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13282
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.917084
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.57228
coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059582
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.06907
extracellular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.173273
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.972008
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39427
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01333
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48361
BRD-K35726223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.7308
C11orf54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33667
Liver epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.096
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.886993
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JJ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16462
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.90435
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913758
GTEx Heart 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	7.43152
NKX2-6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09811
GTEX-QLQ7-1526-SM-2S1QA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06947
ATM_knockdown_113_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.72312
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.35913
RPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59842
small intestine	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.84
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.557629
GSE106661,GSE106665_2_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09745
ZNF382	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18596
CHCHD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45714
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.986294
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.545236
GTEX-W5X1-2326-SM-3GIL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847201
Tongue epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.209
octreotide	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61861
BRD-K44212150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48972
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.869483
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_17277_KO_Kdm1a_SRP185978	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.87249
Renal proximal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.935
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.79897
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.940623
CRCGN012_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78927
hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.717635
mediodorsal nucleus of thalamus_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10953
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20W-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vascular disease	GWASdb SNP-Disease Associations	1.0	0.117791
ZNF765	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26005
apical part of cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.909716
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
carbohydrate transport	GO Biological Process Annotations 2015	1.0	null
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.50556
VDR-23401126-LCL-AND-THP1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-1226-SM-4GICG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
sodium ion transport	GO Biological Process Annotations 2023	1.0	null
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7671
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PMC8088646-13148_2021_1081_MOESM1_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I0-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59024
GTEX-WI4N-1426-SM-3LK7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877751
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
tRNA-splicing ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.383
BRD-K47482563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73377
BRD-A00327403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19244
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
IRF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11256
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
CRCGN016_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6559
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Embryonic structure	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
BRD-K37795187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96389
amygdaloid complex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51967
RCBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25413
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K34161817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1724
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.980007
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Immunosuppression	DisGeNET Gene-Disease Associations	1.0	null
DHRS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10372
Lung squamous cell carcinoma_LUSC_TCGA-56-7823-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NPJ8-2526-SM-2HML8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37373
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79035
TMEM86A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31676
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-SN8G-0926-SM-4DM5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09018
cerebrovascular disease	GWASdb SNP-Disease Associations	1.0	1.25596
COLO800	CCLE Cell Line Gene Expression Profiles	1.0	1.5275
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K53547009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34461
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
stroke	GWASdb SNP-Phenotype Associations	1.0	0.451464
brain_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.205
RVH421	CCLE Cell Line Gene Expression Profiles	1.0	1.43308
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.060613
KLHL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16543
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.134967
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.11132
GTEX-P4PP-2526-SM-3P61P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13829
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.853169
BRD-K46774516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.37665
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07101
BRD-A78125048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68145
renal glycosuria	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.96918
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
converts	GeneRIF Biological Term Annotations	1.0	null
HK-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22874
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04429
BCPAP	CCLE Cell Line Gene Expression Profiles	1.0	1.47672
GSE160817_7_v_6_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
amino	GeneRIF Biological Term Annotations	1.0	null
496100473_TCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.85859
CRCGN015_HEPG2_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64042
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GSE213588_8_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.86231
BRD-K95096346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25365
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.85778
Mouselcells	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
Ost-alpha/Ost-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.972
Paraventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.977
BRD-K71247208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05771
GTEx Esophagus 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	19.1018
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.75469
BRD-K47275094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27463
respiratory failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.239101
GTEX-OOBK-0226-SM-2YUMF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951327
GTEX-Q2AH-1226-SM-48TZL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
single	GeneRIF Biological Term Annotations	1.0	null
BRD-K06330738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12111
GTEX-QDT8-0626-SM-48TYW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00777
CRCGN015_HEPG2_48H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55041
REC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61342
renal proximal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.35222
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.16993
Duodenal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.737
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13828
SLC-mediated transmembrane transport	Reactome Pathways 2014	1.0	null
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.54137
GTEX-RM2N-0926-SM-48FD1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
candidate	GeneRIF Biological Term Annotations	1.0	null
BRD-K10864752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2595
Synaptic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.471
GTEX-WOFL-0726-SM-3MJG4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58511
GSE176008_8_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
COLO818	CCLE Cell Line Gene Expression Profiles	1.0	1.75478
BRD-K60437668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39061
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1278
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
cortical collecting duct cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.724863
NCI-H82	GDSC Cell Line Gene Expression Profiles	-1.0	-1.95222
CRCGN016_MCF10A.WT.HP_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08517
BRD-A98795688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57507
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GN-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902315
SNB75	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
vagus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.420385
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Sepsis	DisGeNET Gene-Disease Associations	1.0	null
Autoimmune disease of endocrine system	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
GTEX-PW2O-0526-SM-2I3DX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879317
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18082
RERFLCAD1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46095
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.72431
acute kidney tubular necrosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.379256
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8639
GTEX-R53T-1526-SM-48FEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873516
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.903745
renal outer medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.18201
sodium ion transport	GO Biological Process Annotations 2025	1.0	null
SYK_DEPLETION_GDS3609_36_human_MCF10A	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCCSTCK140	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86041
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02473
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29Q-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE219274,GSE219276_3_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.70563
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K46239950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15383
TCF4	ChEA Transcription Factor Targets	1.0	null
substrate	GeneRIF Biological Term Annotations	1.0	null
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.781888
cranial nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.298883
BRD-K88925664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89955
PTPRU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59787
CLN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05578
SW837	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36569
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JB-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.980287
Cerebrovascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29686
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18209
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851705
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.872893
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GSE224131_3_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A98714080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73598
GTEX-QLQ7-0726-SM-2I5G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28629
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7072-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sweet taste receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.844
RPMI7951	DepMap CRISPR Gene Dependency	1.0	2.42105
GTEX-QCQG-1826-SM-2S1P2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89088
PMC9942993-pone.0281645.s002.xlsx-AR_as_all_as_maintained-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5748
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37554
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
SF539	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.854487
HEC6	CCLE Cell Line Gene Expression Profiles	1.0	1.38523
COLO 849	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.83334
PMC4595011-pgen.1005555.s001.xlsx-MITF_DOWN-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-QLQ7-1926-SM-2S1R6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34574
CRCGN010_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38505
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
nephrogenic diabetes insipidus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.404557
GTEX-QXCU-0326-SM-2TC63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10353
PCM6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63788
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GRIN2A	Pathway Commons Protein-Protein Interactions	1.0	null
SOX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8633
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.23604
DLG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94634
urine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.818576
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
SKMEL3	CCLE Cell Line Gene Expression Profiles	1.0	2.19452
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EPS8L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39177
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.713601
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
SCG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67403
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MS-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94876980	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.35553
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X5EB-1626-SM-4E3IV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80675
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894738
COLO792	CCLE Cell Line Gene Expression Profiles	1.0	2.99047
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
transporter activity	GO Molecular Function Annotations 2015	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2162
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54699
GTEX-T2IS-0008-SM-4DM75	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-P4QT-0526-SM-2I3EX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18155
carbohydrate:monoatomic cation symporter activity	GO Molecular Function Annotations 2023	1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1278
PMEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78691
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.909
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056474
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39804
lateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.827384
ZIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94235
Skeletal muscle myofibril	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.772
GTEX-TML8-0326-SM-4GICN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25529
PAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5543
transporter	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054715
HCC202	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COLO-792	GDSC Cell Line Gene Expression Profiles	1.0	2.17342
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.738676
BRD-K75806288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08933
MKN28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.837011
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
interstitial nucleus of Cajal, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.63205
TRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18952
BRD-K75293299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53206
thiamine-responsive megaloblastic anemia syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.342
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.58251
BRD-K61248288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48184
CRCGN015_MCF10A_48H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10658
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4355-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K87180723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8219
Sarcoma_SARC_TCGA-DX-A3LW-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K59709463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34009
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.58549
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26012
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.302122
GTEX-XBED-1626-SM-47JYN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00917
BRD-K59919062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43984
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1435
CRCGN009_HEPG2_24H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13837
GTEX-X585-1026-SM-46MW6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49814
SKMEL5	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
ASCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21263
GTEX-XMK1-0926-SM-4B66X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915099
Microbody membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.724
extracellular vesicular exosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.173273
PI4K2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37809
GTEX-N7MT-0726-SM-3TW8S	GTEx Tissue Sample Gene Expression Profiles	1.0	3.76792
CRCGN015_MCF10A.WT.HP_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40681
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-UPK5-1826-SM-3GAEB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52813
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50686
BRD-K08558441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51982
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.56483
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Dorsal claustrum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67024
BRD-A09115727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90782
smallintestine_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.27698
ADAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21504
SLC12A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94188
liver epithelial cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.829453
SLITRK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76348
BRD-K56591923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10896
SF767	DepMap CRISPR Gene Dependency	1.0	4.20593
NRF1	ENCODE Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2851-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.872893
BRD-K19387722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22878
DAPAGLIFLOZIN PROPANEDIOL	DGIdb Drug Targets 2026	1.0	1.10275
WM88	DepMap CRISPR Gene Dependency	1.0	2.45558
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CRCGN008_HEPG2_24H:A06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0257
BRD-K16843478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30921
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.488667
MEWO	CCLE Cell Line Gene Expression Profiles	1.0	1.70607
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
RHOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14024
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-RNOR-0008-SM-48FEY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.037
K029AX	DepMap CRISPR Gene Dependency	1.0	11.6236
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K8-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91138
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0679
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PMC4595011-pgen.1005555.s003.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
IGR1	CCLE Cell Line Gene Expression Profiles	1.0	1.90634
BRD-K02445308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56145
PMC4595011-pgen.1005555.s001.xlsx-BPTF_DOWN-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7305081-10120_2020_1045_MOESM1_ESM.xlsx-Tab2-Mutation-MAF_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64301
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041288
BRD-K93483334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21442
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
smallintestine_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.50538
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25614
Activating signal cointegrator 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.1
Ileocecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.609
496100593_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58861
pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.108108
TGBC1TKB	DepMap CRISPR Gene Dependency	1.0	2.24456
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.882562
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912113
BRD-K19168437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25885
BRD-K24156533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05641
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09609
Lung adenocarcinoma_LUAD_TCGA-49-6744-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.72822
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05309
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
MFHAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6548
BRD-K54621976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50447
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SK-01B-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06138
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8509
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7221
GSE213588_10_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Figure_4f-FOSL2_ChIP_WT-exclusive_genes_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
gramine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33003
Gut wall	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.222
GSE130956_0_v_1_icaritin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K17209411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23799
Sarcoma_SARC_TCGA-DX-A23R-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49293
BRD-K45315294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15972
BRD-K64571715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29074
ventral anterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.877847
SNU81	CCLE Cell Line Gene Expression Profiles	-1.0	-2.43542
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.49754
macula densa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.489057
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25572
migraine	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.155378
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
MLLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34857
urinary tract obstruction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.168854
GTEX-REY6-0426-SM-2TF5G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61463
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3393
glucose	GeneRIF Biological Term Annotations	1.0	null
GTEX-QV31-1426-SM-2S1QD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Neurotic Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
ZNF57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19387
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
MTFR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20662
GTEX-PWOO-0926-SM-2I3EC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69843
MYT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77786
H3K27me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3497
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.2991
GCT	DepMap CRISPR Gene Dependency	1.0	2.47324
BRD-K44779670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32898
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1581
determination	GeneRIF Biological Term Annotations	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4033
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.29658
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.299
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
skin cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060495
CRCGN008_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53275
GTEX-XUJ4-0726-SM-4BOOP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04032
henles loop	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.845805
LICOGLIFLOZIN	DGIdb Drug Targets 2026	1.0	1.47033
lat1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
duodenum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.161338
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K41620124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15746
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18166
TESK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4242
GSE213588_9_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
cotransporter	GeneRIF Biological Term Annotations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.89078
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8317-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GSE94849_7_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K00057967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47226
BRD-K71592817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27285
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.05986
GTEX-UJMC-0326-SM-3GAE2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.942919
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30391
Acute Myeloid Leukemia_LAML_TCGA-AB-2973-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K97247086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24296
diclazuril	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78264
CDKN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12433
liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.432991
collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.12571
similar	GeneRIF Biological Term Annotations	1.0	null
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.195918
Lung squamous cell carcinoma_LUSC_TCGA-77-7142-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K09699976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26376
Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20243
GSE173873_1_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4391
Prostate	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.14722
GTEX-T6MN-0626-SM-32PM9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94795
CCER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32638
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-XUZC-1426-SM-4BRV3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05944
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
Perturb_12667_OE_MX2_SRP308919	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.63201
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42078
TMEM39B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13696
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055738
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3984
20460173-ImmPortComprehensiveListofImmune-RelatedGenes	GeneSigDB Published Gene Signatures	1.0	null
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3098
ZNF784	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27886
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z3-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32209551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06003
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HLA-A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06824
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.862745
Perturb_17250_KO_Il17a_SRP069071	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PRICKLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25782
GTEX-PLZ6-1126-SM-3P5ZR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857147
GTEX-WXYG-0926-SM-3NB2O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973927
BET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58837
GTEX-QDT8-2526-SM-48TYX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69197
membrane	GeneRIF Biological Term Annotations	1.0	null
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18209
GSE193258,GSE193259_5_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38045
SKMEL5	CCLE Cell Line Gene Expression Profiles	1.0	2.40871
A3KAW	DepMap CRISPR Gene Dependency	1.0	4.7183
sglt	GeneRIF Biological Term Annotations	1.0	null
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K03848296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1223
Bae	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93312
TTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48571
MAN2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17551
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8046
Urinary tract infection	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-4104-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma	GeneRIF Biological Term Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3349-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.868937
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-02A-12R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A08759443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08398
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.9459
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043593
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69033
Perturb_9257_KO_Il17a_ERP107271	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.59186
GTEX-WH7G-1026-SM-4LVML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PKCA_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37462
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3408
BRD-K74056311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29755
BRD-K44548010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30747
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
root	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.212413
GTEX-U3ZH-0226-SM-3DB7B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16975
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERTUGLIFLOZIN	DGIdb Drug Targets 2026	1.0	1.47033
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.829167
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.918502
REST_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH7	CCLE Cell Line Gene CNV Profiles	1.0	1.98608
GSE173873_10_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.450657
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.035
BRD-K00808919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0081
SUIT-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.54983
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04883
G141	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00259
MTRFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65947
monovalent inorganic cation transport	GO Biological Process Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.09837
BRD-K36617229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04901
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GSE193157_0_v_1_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89939
ADD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03028
Circular smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.946
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30685
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K61753872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20717
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
D502MG	DepMap CRISPR Gene Dependency	1.0	2.00886
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.1621
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25051
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.05841
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Basal labyrinth	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.797
BRD-K25866212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68628
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Intestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.88
CELSR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3905
cellular_component	GO Cellular Component Annotations 2015	1.0	null
TMEM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33194
Hexose transport	Reactome Pathways 2014	1.0	null
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.931
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.157943
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.44249
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.652
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MU-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
into	GeneRIF Biological Term Annotations	1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IMPACT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85738
enterocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.424581
C32	CCLE Cell Line Gene CNV Profiles	1.0	1.47371
TECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03646
MYO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02873
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86836
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35922
proximale tubular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.406947
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.93966
GSE168797_2_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6612
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-P4QS-2626-SM-2I3EV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863538
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17389
BRD-K99377541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.993
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81746
DNAJB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04697
GSE210870_0_v_2_snai1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.939576
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3223
GSE134375_4_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Glycogen storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.235
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.322
duodenum	HPA Tissue Gene Expression Profiles	1.0	1.40876
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.918463
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04956
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.89714
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5271
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K96101240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39096
JVM-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076654
BRD-K09376136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37866
BRD-K72648699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02576
DCPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72681
CRCGN012_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92427
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Glutamate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.845
BRD-K31889353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03283
BRD-K61440521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22113
GTEX-QLQW-1326-SM-2S1QS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919452
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1701
BRD-K66299486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51339
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.8695
MRPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52748
DNAJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31929
BRD-K84423439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26938
BRD-K18316646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34329
GTEX-UPK5-1126-SM-3GAEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24774
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05474
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4991-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35665
GTEX-T6MN-0002-SM-3NMAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
smallintestine_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.40015
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0244
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-SSA3-0526-SM-32QPL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04151
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045187
Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gut	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.102523
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
Transport of small molecules	Reactome Pathways 2024	1.0	null
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23531
Sodium/solute symporter, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
S100A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38884
HT29	BioGPS Cell Line Gene Expression Profiles	1.0	1.17985
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26326
SKMEL30	CCLE Cell Line Gene Expression Profiles	1.0	2.18739
APUD cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.653
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4117-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEL9217	DepMap CRISPR Gene Dependency	1.0	2.79256
STEEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31272
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.886993
GTEX-P4PP-0926-SM-48TBZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59022
BRD-K75007044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86882
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.37379
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A148-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92669
blood plasma	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.540981
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.07515
BRD-K34985075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82178
chr22_32353182_G_A_b38	GTEx eQTL 2025	1.0	1.79074
CAMK2G	Pathway Commons Protein-Protein Interactions	1.0	null
Renal glycosuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.986
SUDHL10	DepMap CRISPR Gene Dependency	1.0	4.21163
STN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66008
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
disease	GWASdb SNP-Disease Associations	1.0	0.031241
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
NEFL	Pathway Commons Protein-Protein Interactions	1.0	null
leptospirosis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.909376
SK-MEL-3	GDSC Cell Line Gene Expression Profiles	1.0	2.03173
BRD-K15620114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22952
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.32406
SNU478	CCLE Cell Line Gene CNV Profiles	1.0	1.4171
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWN1-1726-SM-2S1O9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0539
GSE202434,GSE202438_10_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T2IS-0626-SM-32QP6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850764
periods	GeneRIF Biological Term Annotations	1.0	null
Metabolism of carbohydrates	Reactome Pathways 2014	1.0	null
amygdaloid complex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.9937
GTEX-P4PQ-0526-SM-2HMKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01741
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-A4W0-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.82556
localization	GO Biological Process Annotations 2015	1.0	null
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	1.0	1.2322
myenteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.679025
respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.057245
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.0848
YKG1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03276
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.592
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
OCIM2	DepMap CRISPR Gene Dependency	1.0	3.89235
BRD-K43624274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07932
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9414
BRD-K32972218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03596
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7207
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Lung squamous cell carcinoma_LUSC_TCGA-43-6647-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XYKS-1226-SM-4BRVI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40814
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
kidney	GeneRIF Biological Term Annotations	1.0	null
BRD-K53662389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73256
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3243
all	GWASdb SNP-Phenotype Associations	1.0	0.032532
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.831175
GTEX-UJMC-2026-SM-3GADR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39312
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18209
CRCGN008_HEPG2_24H:A15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1652
BRD-K93675803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14711
GTEX-N7MS-2326-SM-2HMLD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71246
BRD-K88441035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12859
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.48578
BCKDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41875
BRD-K49628278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20708
CRCGN013_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2177
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
scutellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.70927
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-A4SR-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FZD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56835
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6101
Glycogen metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.234
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855127
BRD-K59560948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51369
GTEX-RWS6-2326-SM-2XCB4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7027
PRMT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66408
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07385
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.950653
SAP30BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33334
CLMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24788
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
Perturb_15514_KD_E2F1_SRP314859	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.68976
adult respiratory distress syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.416521
GSE148096_1_v_0_erlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
XRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65371
KMS26	CCLE Cell Line Gene CNV Profiles	1.0	2.23342
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
Central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.941444
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854102
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K74817844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37049
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
melanoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06295
BRD-K70237115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13167
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37308
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K11310449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0941
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K64992851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82122
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4999-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K62263376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30024
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.484376
GM1600	BioGPS Cell Line Gene Expression Profiles	1.0	0.856738
BRD-K09454191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04718
kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.308118
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Lung squamous cell carcinoma_LUSC_TCGA-77-7138-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LCLC103H	CCLE Cell Line Gene CNV Profiles	-1.0	-2.29812
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0683
GTEX-R55E-0008-SM-48FCG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
chr22_32371551_A_G_b38	GTEx eQTL 2025	1.0	1.06164
SOWAHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8585
adrenal gland hyperfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.140438
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.54013
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.121445
proliferative diabetic retinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.304142
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
cortical collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.844545
Myenteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.674
Mesothelioma_MESO_TCGA-LK-A4NW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4UY-1426-SM-4AD6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66173
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.94674
Type VI protein secretion system complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.744
GSE163862_0_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.055749
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10R-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3605
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Lung adenocarcinoma_LUAD_TCGA-55-6972-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0127
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.842973
BRD-K60937893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1823
GTEX-S7SE-0226-SM-2XCD4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09103
BRD-K13888422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4053
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
RPMI-6666	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P4QS-0226-SM-3NB1U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850374
BRD-K18313650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29895
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.855127
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.861678
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ZBTB26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50547
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.832913
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LN319	DepMap CRISPR Gene Dependency	1.0	3.39615
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18209
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0829
BRD-K24525269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29306
CRCGN008_HEPG2_24H:I03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.67725
MPP89	DepMap CRISPR Gene Dependency	1.0	2.15947
BRD-K76738405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01635
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
IPC-298	GDSC Cell Line Gene Expression Profiles	1.0	1.83719
MZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.906928
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0441
hyperinsulinism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.180652
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.807305
BRD-K32718105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00058
renal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.21446
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.97679
GTEX-VUSH-0008-SM-47JWK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.817
Whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Portal vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.683
L-6 myoblast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
IK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48167
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04872
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12411
COLO679	CCLE Cell Line Gene Expression Profiles	1.0	2.72104
ATXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30338
ECC12	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46488
GTEX-TML8-2026-SM-32QOP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851068
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K67194214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1773
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K45813167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48078
DOK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-S341-0326-SM-2XCAU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995547
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Type 1 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
Tbx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.4875
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SCML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12422
Small intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.02
GSE224131_2_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cecum cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.065
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53794
GOLM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33119
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47465
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A44O-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.842275
GTEX-RUSQ-1926-SM-2TF6K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Renal distal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.111
RUFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27202
GTEX-WHSE-1126-SM-3NMBU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
SW982	DepMap CRISPR Gene Dependency	1.0	2.52395
Lung squamous cell carcinoma_LUSC_TCGA-51-4080-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07993
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.17709
GTEX-OXRP-0326-SM-33HBJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06248
phloem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.410111
LSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46751
BRD-K10696228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74787
Dicarboxylic aminoaciduria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
BRD-K59191599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28875
kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.501527
Inositol transporters	Reactome Pathways 2014	1.0	null
CRCGN015_MCF10A.WT.HP_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30986
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01014
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.73376
Perturb_98_KD_INTS8_SRP262320	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.35151
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K62983405	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43859
Vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.775
Atf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5204
OPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37821
GTEX-QCQG-0326-SM-2I3ES	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876295
BRD-A88691416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2203
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22699
GTEX-RU1J-0226-SM-2TF5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31694
CRCGN012_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57443
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.928127
Perturb_17251_KO_Il17ra_SRP069071	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.2621
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25881
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52546
proximale tubular epithelium cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.719113
brush border	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.326829
JEKO1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81851
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.852529
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
STAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48323
PTGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32563
PMC10248509-Data_Sheet_5.CSV--GSE66724_DE-Genes_AND_GSE41177_DE-Genes_NOT_Autophagy_NOT_GSE58294_DE-genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157233_2_v_4_a1cf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NV-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cranial nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.622
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Juxtaglomerular apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.124
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78017
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.19454
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K57517066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.73812
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.935212
heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.244696
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Lung adenocarcinoma_LUAD_TCGA-55-6980-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.917366
GSE139987_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K32582260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10864
BRD-K97526959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04389
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.435672
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
outer SZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.928869
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
ischemic stroke	GWASdb SNP-Phenotype Associations	1.0	1.1002
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K35588268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27508
GTEX-V1D1-0003-SM-3NMDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Kidney Chromophobe_KICH_TCGA-KN-8433-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSC-2	GDSC Cell Line Gene Expression Profiles	-1.0	-2.21209
GTEX-QVJO-1826-SM-447C9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00338
BRD-K27109474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2092
BRD-K40034229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56035
MSI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42546
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70322
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
MRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42032
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.920191
BRD-K62800316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15952
BRD-K93165404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00021
mutating	GeneRIF Biological Term Annotations	1.0	null
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	2.07594
BRD-K60631127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02094
Disease	Reactome Pathways 2014	1.0	null
ethoxyquin-3764	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X4XY-0526-SM-46MW1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EF-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW780	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66063
IPC298	CCLE Cell Line Gene Expression Profiles	1.0	1.68258
SLC-mediated transmembrane transport	Reactome Pathways 2024	1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05809
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.326
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.39146
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Longitudinal smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Sarcoma_SARC_TCGA-SI-A71O-06A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
compared	GeneRIF Biological Term Annotations	1.0	null
Perturb_13306_KO_Hnf4a/Cdx2_SRP049189	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08864
Hypoglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.78
CRCGN015_MCF10A.WT.HP_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04502
fanconi syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.557897
SLC27A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77792
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.872382
TOFOGLIFLOZIN ANHYDROUS	DGIdb Drug Targets 2026	1.0	1.47033
REST_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29L-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P78B-0926-SM-2I5FA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18237
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K17649115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87642
GTEX-U3ZH-1426-SM-4DXSR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930897
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.31381
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.963189
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.913758
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GSE158197_6_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9399
BRD-K48592348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11762
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.442194
PMC9942993-pone.0281645.s002.xlsx-AR_as_non-adaptive_as_maint-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SLC25A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14501
diabetic retinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.131105
GSE173873_8_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Thyroid	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.18122
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0294
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3236
active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
PMC9942993-pone.0281645.s002.xlsx-AR_as_all_as_maintained-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96664
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14193
Esophagus - Mucosa	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.756318
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K62157654	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63683
Chylomicron	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.936
hsa-miR-3658	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
RRP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45729
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.408212
cefepime-6159	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-V1D1-0826-SM-3P5ZA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97027
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0198
Cerebrovascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-N7MT-0126-SM-2D7VT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85273
spinal trigeminal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.933465
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K05702937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27709
BRD-K04402444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54531
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Psoriasis vulgaris_Skin tissue_GSE14905	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.65058
POTEF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09804
secondary active transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.76655
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.01745
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.85404
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
cos-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.406694
Acute Myeloid Leukemia_LAML_TCGA-AB-2964-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47999752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34633
Prostate adenocarcinoma_PRAD_TCGA-HI-7169-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.4672
BLTP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40252
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.873398
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13499
principal sensory nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06921
AsPC-1	GDSC Cell Line Gene Expression Profiles	-1.0	-3.18462
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4283
enteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.667215
BRD-K17171256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26619
ZNF747	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91997
REST	ENCODE Transcription Factor Targets	1.0	null
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05912
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.858
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72225
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18166
BRD-K78965436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22129
GTEX-WZTO-0426-SM-3NM99	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939718
Ec	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.36
CHST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40855
glucose:sodium symporter activity	GO Molecular Function Annotations 2023	1.0	null
BRD-A94420133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09332
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898046
Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GSE226249_5_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K18462967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30252
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.01545
CAL-148	COSMIC Cell Line Gene Mutation Profiles	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4869
CRCGN014_HEPG2_3H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36591
CEP120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65086
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.91963
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.957469
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K26620362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45985
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-UPK5-2326-SM-3P5Z8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.50691
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934355
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5517
Perturb_9406_KD_GATA6AS_SRP279802	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.14868
ANKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63914
LCLC-103H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1458
GTEX-T2YK-2226-SM-32QPT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16739
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.844284
PTCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41575
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K55135464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30247
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
RNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86075
CAMK2B	Pathway Commons Protein-Protein Interactions	1.0	null
renal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.721577
GRIN2D	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.283899
C32	DepMap CRISPR Gene Dependency	1.0	2.79322
HUP-T4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U8T8-2326-SM-3DB96	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07608
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComDown-List-Gene_name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148692,GSE148695_1_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148695,GSE167281_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K39131701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02539
NCIH1869	CCLE Cell Line Gene CNV Profiles	1.0	1.69383
Adrenocortical carcinoma_ACC_TCGA-OR-A5LB-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040325
BRD-K66865641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.50961
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K71132173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23809
SMRT-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ACTR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02221
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GSE213588_10_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
gut epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.643263
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.833172
CAMK2D	Pathway Commons Protein-Protein Interactions	1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9211
establishment of localization	GO Biological Process Annotations 2015	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.03039
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.86123
BRD-K55044152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83885
GTEX-RWS6-0001-SM-3NMAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cotyledon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.597263
496100394_TCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.26949
BRD-K66896657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00728
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.3786
vestibular nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25892
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40276
INSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03885
psych	GAD High Level Gene-Disease Associations	1.0	0.293278
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
SSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53914
BRD-K22447639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53924
sensor	GeneRIF Biological Term Annotations	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
NFXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46548
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.469987
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
orlistat-6383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HOP62	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
TXNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29526
SLC38A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34169
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K59095205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11373
HCaRG_OE_GDS2426_711_human_HEK293 kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
cholinergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.346298
EBC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
outer SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30238
NCIH2342	CCLE Cell Line Gene CNV Profiles	1.0	1.41807
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K45318035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87844
GTEX-R53T-0226-SM-48FEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.032598
NFIX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19704
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18209
Area postrema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.157
IGR-37	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.64531
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A4P5-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
specificity	GeneRIF Biological Term Annotations	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.96664
NSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53909
CERS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20788
UACC62	CCLE Cell Line Gene Expression Profiles	1.0	1.38179
SHISA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24533
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7751
GTEX-PLZ6-0126-SM-48TC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62995
GTEX-XOT4-0526-SM-4B66O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
R3HDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12222
CRCGN008_HEPG2_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28545
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K44244207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87274
GTEX-T2IS-1926-SM-4DM74	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937435
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7Q0-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K71514806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3206
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11056
m1 melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.338914
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6448
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CREB5_CREB5	Rummagene Transcription Factor Associations 2026	1.0	null
fatty-acyl-CoA synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.621
BRD-K93819193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83075
BRD-K32120119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1409
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A706-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Tongue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.301
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-93-A4JP-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100456_TCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31419
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
L3.6pl cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.529
GTEX-O5YW-0526-SM-2YUMX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24045
metal ion transport	GO Biological Process Annotations 2015	1.0	null
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29521
BRD-K09975370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81424
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9057
PMC9942993-pone.0281645.s002.xlsx-AR-as_all-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q7-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LCLC103H	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62188
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11923
diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.615138
PMC4595011-pgen.1005555.s003.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K84054400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06088
medial intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1819
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8271
NCI-H226Br cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.707
BRD-K44260904	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81338
GSE86813,GSE86814_0_v_1_atf7ip_human	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2458
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19131
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854102
CAL33	CCLE Cell Line Gene Expression Profiles	-1.0	-2.71877
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-WYVS-2526-SM-3NMAT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K97086358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01469
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
Renal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.822
SDHAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17125
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.28515
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04995
GTEX-XAJ8-0726-SM-47JY5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
RAB26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68591
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A431	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BON-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.741
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-X8HC-0726-SM-46MWG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858921
NCI-H716 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.218
GTEX-WHPG-1426-SM-3NMBB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886701
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.9792
BRD-K39498165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36873
BRD-K24047785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89647
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
vivo	GeneRIF Biological Term Annotations	1.0	null
INCENP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57197
A101D	GDSC Cell Line Gene Expression Profiles	1.0	1.76434
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.40813
Jejunal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
SOHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74686
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.978729
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.26805
GSE148692,GSE148695_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SQSTM1_OE_GDS2653_651_human_IMR-32 neuroblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K05286676	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.22084
GTEX-OXRO-0326-SM-33HBM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.028
RFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76383
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
ORAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02573
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.217554
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A820-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WK11-0926-SM-3NMAU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58808
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22874
SU-DHL-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.852529
viscus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33574
Asthma, allergic_Bronchial epithelium_GSE3004	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.84362
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
GTEX-XMK1-1126-SM-4IHJ8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991888
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.70507
primary bacterial infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.189244
GTEX-U3ZH-0526-SM-3DB75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0446
Transmembrane transport of small molecules	Reactome Pathways 2014	1.0	null
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
SNUC4	DepMap CRISPR Gene Dependency	1.0	3.42527
BRD-K67835515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52622
BRD-K45043387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03533
GTEX-QMRM-0826-SM-3NB33	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952185
PBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61513
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33657
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.910835
PRDM15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5303
BRD-K57042334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65532
UNCX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29471
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.830492
GTEX-R55C-0626-SM-2TF4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4339
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K89537738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6553
LY-294002-5576	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CRCGN015_HEPG2_48H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.23626
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
YAMATO	DepMap CRISPR Gene Dependency	1.0	3.67436
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
RAB38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39994
GTEX-T2YK-0326-SM-4DM7D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968421
GTEX-PX3G-2526-SM-48TZV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859081
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.2691
Benign familial infantile epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.286
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K29379469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10343
GSE165071,GSE165072_1_v_0_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
YBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19839
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53922
lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.071688
changes	GeneRIF Biological Term Annotations	1.0	null
BRD-K07390518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7323
BRD-K85622666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75897
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4937
Lung adenocarcinoma_LUAD_TCGA-50-5932-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.833819
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9307
Becker	GDSC Cell Line Gene Expression Profiles	-1.0	-1.46542
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8924
GTEX-O5YW-0008-SM-4E3IE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8854
membrane part	GO Cellular Component Annotations 2015	1.0	null
BRD-K83708628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35866
SPART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33365
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.7321
BRD-K65506286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99275
GTEX-OXRK-0826-SM-2HMK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
extracellular region part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044003
GTEX-X638-0426-SM-47JY2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861938
MAK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57451
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Perturb_13927_OE_ESRRG_SRP363188	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.15705
GTEX-WVLH-0626-SM-3MJG7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17365
Lymphoma_burkitts(Daudi)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.895159
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Attention Deficit Disorder	DisGeNET Gene-Disease Associations	1.0	null
GTEX-RN64-1226-SM-2TC6E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.30242
BRD-K73895377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03447
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.899074
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4774-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4595011-pgen.1005555.s001.xlsx-MITF_DOWN-regulated-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882419
Subfornical organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
BRD-K83270266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.146
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.982908
GTEX-RTLS-0926-SM-2TF5X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72776
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IPRAGLIFLOZIN	DGIdb Drug Targets 2026	1.0	1.47033
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.808887
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.72085
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-R53T-0008-SM-48FEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0242
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.43489
congestive heart failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.451831
GTEX-UJHI-1326-SM-4IHJO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11788
GTEX-Q2AG-0526-SM-2S1PW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Bladder Urothelial Carcinoma_BLCA_TCGA-YC-A8S6-01A-31R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5498
Sodium	HMDB Metabolites of Enzymes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YI-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.28424
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CRCGN011_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5778
BRD-K11641139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15351
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.45512
SLC29A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52274
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder transitional cell papilloma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
Kidney renal papillary cell carcinoma_KIRP_TCGA-UN-AAZ9-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KW-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-2.22767
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.234191
IGR1	CCLE Cell Line Gene CNV Profiles	1.0	1.80778
BRD-K63154470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24435
cell-cell junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.203361
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-W5X1-0008-SM-4LMKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
RRP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72231
P2RX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09878
CRCGN013_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80789
GSE202017,GSE202018_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
connecting tubule cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.275794
myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.166319
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.055622
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47717
CL-34	COSMIC Cell Line Gene Mutation Profiles	1.0	null
placenta	HPA Tissue Gene Expression Profiles	-1.0	-1.38213
BRD-K73874262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05912
GTEX-U3ZM-1126-SM-4DXUB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.982738
Median eminence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.11
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UL-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SSA3-0126-SM-32QPU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97564
Hailey-Hailey disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10926
lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.067962
BRD-K78596805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.09654
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05785
NR3C1-34362910-WISTARRAT-HIPPOCAMPUS-STRESS	ChEA Transcription Factor Targets 2022	1.0	null
limb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.657054
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2234
GTEX-XOT4-1426-SM-4B65T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38187
BRD-K24396618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06676
Intestinal cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.037
BRD-K07557785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20805
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39931
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919452
CCD-18Co cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
BRD-K56013842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15181
BRD-K07196884	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2137
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lung_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.895902
BRD-K27824953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34723
BRD-K18598482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18437
GTEX-QEL4-0826-SM-3GAF2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982089
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7828-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6836-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22066
DLG4	Pathway Commons Protein-Protein Interactions	1.0	null
Rinm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.605
GTF2H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42045
UACC257	CCLE Cell Line Gene Expression Profiles	1.0	1.97131
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PMC9942993-pone.0281645.s002.xlsx-AR_as_non-adaptive_as_maint-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QXCU-0626-SM-2TC69	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826388
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.62052
ATP11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1486
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.07511
hyperaldosteronism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.470332
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
JHH7	DepMap CRISPR Gene Dependency	1.0	2.26762
DLST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33799
BRD-K03093950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23017
Perturb_3997_KO_HIC2_SRP317427	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.26549
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.8005
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.831175
CHMP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70365
RFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19114
IRF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21002
placenta_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
NUBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81381
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Vagus nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.736
IZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06377
BRD-K23440419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99375
NCI-H196	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854102
RPL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08194
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
renal distal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.02381
BRD-K18077898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27802
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.852529
Perturb_12666_OE_GFP_SRP308919	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.1978
retinopathy of prematurity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.384822
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	1.0	2.81282
FAM181B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24489
GTEX-S7SF-0226-SM-3K2BI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16942
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Arterial tortuosity syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
GM2493	BioGPS Cell Line Gene Expression Profiles	1.0	1.02285
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927051
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3319-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K19657374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37749
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K12986423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.844
Macula densa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.417
BRD-K90562751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46761
CRCGN012_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7175
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.631
KNS81	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42859
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K95148987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.80027
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K03765511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47654
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4171
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11819
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2969
GTEX-OHPK-2326-SM-3MJH2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902984
GTEX-P44H-1126-SM-48TBU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929768
D-glucose transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
TEPSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89934
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.43078
PTK7_KD_GSE50138_675_human_H2009	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
central nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53025
BRD-K48691065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35052
SCABER	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2709-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047251
GTEX-WYJK-1626-SM-3NM9J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940297
GSE210885_2_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
ERVV-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59751
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.854102
DSN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56553
NOTCH_INHIBITION_GDS2794_61_human_MOLT4 (T-cell acute lymphoblast leukemia) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Glucosidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.848
ZIC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73269
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057819
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044234
GTEX-R55C-0008-SM-48FCF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
AAMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84187
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K84518331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04734
BRD-K97226655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90348
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63817
BRD-K39649723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43675
GTEX-QEG4-0526-SM-48TZD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47343
GSE62292,GSE62295_2_v_0_col4a3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.92213
GTEX-TSE9-0726-SM-3DB8C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29056
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Radicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.616
SH10TC	DepMap CRISPR Gene Dependency	1.0	3.27761
UMRC7	DepMap CRISPR Gene Dependency	1.0	2.00291
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.839749
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U0-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.842279
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.11525
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.486
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS	ChEA Transcription Factor Targets 2022	1.0	null
Artery disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
IGR37	CCLE Cell Line Gene Expression Profiles	1.0	2.0477
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PLEKHG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0938
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Jejunum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.767
Nuclear receptors meta pathway	WikiPathways Pathways 2024	1.0	null
Ventromedial hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.019
RPL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16886
GTEX-T5JW-1226-SM-3GACY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828844
BRD-A50287893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42102
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.451813
GTEX-Q2AH-0426-SM-2I3EP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01127
melanocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060651
ALVA31	BioGPS Cell Line Gene Expression Profiles	1.0	0.909837
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.84367
GTEX-T6MN-0226-SM-32PMD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917476
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.498085
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908173
Small intestine epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.886
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
ae2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.823
CRCGN008_HEPG2_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.01275
MUSTN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62247
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.78017
MYCN	ChEA Transcription Factor Targets	1.0	null
SOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30521
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
those	GeneRIF Biological Term Annotations	1.0	null
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33257
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
UVSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36155
GTEX-PX3G-3026-SM-48TZR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23485
Perturb_7286_KD_HNRNPG_SRP064870	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.40272
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Enterokinase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5494
piriform cortex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29508
NDUFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08574
Depressive Disorder, Major	HuGE Navigator Gene-Phenotype Associations	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8344-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.936391
PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
UACC-62	GDSC Cell Line Gene Expression Profiles	1.0	1.77673
ZNF721	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89135
ABHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76336
REMOGLIFLOZIN ETABONATE	DGIdb Drug Targets 2026	1.0	4.411
BRD-K37283718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72884
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DDX18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84613
SNU886	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56477
BRD-K75065750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99034
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1521
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02827
GTEX-POYW-1226-SM-2XCEP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17691
GTEX-QV31-1326-SM-2S1QE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944924
BRD-K40627098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18159
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1797
BRD-K87511374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47258
Gut epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.123
Renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.83
Renal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.655
NFKBIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17704
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14186
Perturb_3941_OE_SNAI2_ERP138229	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.51652
STAT3	ENCODE Transcription Factor Targets	1.0	null
abnormality of the cerebral vasculature	GWASdb SNP-Phenotype Associations	1.0	0.326354
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
GSE214514_1_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K27719710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21205
GTEX-WXYG-2226-SM-4E3IM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990603
Cholinergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.922
ZNF729	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81688
OS-RC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T8EM-0226-SM-3DB7C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843449
BRD-K82374143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32543
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.1221
BRD-K19776718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.41512
Chloride channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.994
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.33542
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82432417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11708
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.81465
FAM76A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73724
496100499_PCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.24735
xylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.638809
docebenone	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21892
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.26345
chr22_32341341_G_A_b38	GTEx eQTL 2025	1.0	1.79717
endocrine pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.203604
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.0876
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.12776
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-SUCS-0002-SM-3NMAJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.43115
LIVF001-016	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09651
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
KM12	BioGPS Cell Line Gene Expression Profiles	1.0	1.14548
Perturb_4898_KO_NSUN6_SRP233222	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.89668
depressive disorder, major	GAD Gene-Disease Associations	1.0	null
Enteric nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.177
GAK	GDSC Cell Line Gene Expression Profiles	1.0	1.67866
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1181
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
outer SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31264
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
jejunal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.34334
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25881
DLX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.98905
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.918927
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HL-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KIF20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24101
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.487307
ion transport	GO Biological Process Annotations 2015	1.0	null
MZ7-mel	GDSC Cell Line Gene Expression Profiles	1.0	2.42856
GTEX-VJYA-0326-SM-3GAEX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53415
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9163
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05233
CRCGN015_MCF10A.TP53.M_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1143
Lung adenocarcinoma_LUAD_TCGA-50-5939-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCRF-CEM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K44624253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77957
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
DBTRG-05MG	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TE1	DepMap CRISPR Gene Dependency	1.0	2.51643
BRD-K74568352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35504
Cerebral arterial disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
BRD-K06237859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56035
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05442
protoxylem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.231343
JHH2	CCLE Cell Line Gene CNV Profiles	1.0	2.40433
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.94246
496100366_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5962
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.194
novobiocin-na	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.36677
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7807
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63U-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HMGB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35908
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K49005954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29133
BRD-K71414336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64238
Peroxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.725
BRD-K14255526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16815
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K46623934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28523
UPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17613
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41039
DMS53	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13427
Glycogen storage diseases	Reactome Pathways 2014	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
melanoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061506
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K87053028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04765
NUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56068
PUM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14896
BRD-K67666705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61373
BRD-K85567359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72696
BRD-K51196703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12196
GTEX-OHPK-2626-SM-2HMK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0403
BRD-K69468381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30137
GTEX-U412-0826-SM-3DB9K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20588
ACKR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31968
primary auditory cortex (core)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68377
Cerebrospinal T-tau levels	GWAS Catalog SNP-Phenotype Associations	1.0	0.22914
BRD-K07431402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33698
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CRCGN016_MCF10A.TP53.M_24H:P16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10998
DMBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1439
BRD-K75657700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.75184
GTEX-SN8G-1526-SM-4DM79	GTEx Tissue Sample Gene Expression Profiles	1.0	1.86602
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
mineral metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.078036
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9101
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96235
Lung adenocarcinoma_LUAD_TCGA-MN-A4N4-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K03849840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20266
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16554
EZH2	ENCODE Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE214382,GSE214383_0_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
acute kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.290103
Perturb_16531_KO_Cdk8/Cdk19_SRP351257	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.40366
BRD-K45091989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40926
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1818
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
C1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4462
PTEN_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.886993
SLC25A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93361
GTEX-PWN1-0226-SM-2S1OZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891724
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.3823
BRD-K32480492	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33805
GTEX-VJYA-0001-SM-3NMDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
exosome (rnase complex)	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.173003
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81043
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
DYRK1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48869
BRD-K91022335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51843
GTEX-X15G-1626-SM-3NMB3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857015
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.567227
GTEX-T2IS-0526-SM-32QP9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05089
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.509197
Tanycyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.13
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.18559
Gastrointestinal endocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.65
BRD-K16267084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21893
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08547
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26684
GTEX-XUZC-2026-SM-4BRW9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
SLFN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25397
GTEX-WFJO-0226-SM-3GIKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850735
CRCGN012_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.28751
Lung adenocarcinoma_LUAD_TCGA-44-5645-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.545236
WARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7417
CRCGN010_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37154
Carotid body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
SLFN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30325
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T8-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
procambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.188555
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9601
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.2878
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
MSH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35428
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.81465
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33126
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42074
CENPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05055
GTEX-V955-2426-SM-3GAEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K31215362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07615
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.99698
chr22_32353798_TAC_T_b38	GTEx eQTL 2025	1.0	1.8731
SNU719	CCLE Cell Line Gene Expression Profiles	-1.0	-2.42895
GSE168602,GSE168604_2_v_6_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K63008302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21967
BRD-K28790383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00343
URB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19505
CALU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18809
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.954198
BRD-K03070961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24054
IGROV1	DepMap CRISPR Gene Dependency	1.0	2.13137
PCBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49584
CRCGN015_MCF10A_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.34089
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GSE209698_2_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2655-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65134
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6031
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
MES-23.5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.726
KLKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21075
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33327
Carboxypeptidase N deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
Hypertension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.063
ZNF544	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03738
BRD-K38935430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19677
LN464	CCLE Cell Line Gene Expression Profiles	1.0	1.80551
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.1993
BRD-K19770687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35709
type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.455978
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.838717
Hereditary spastic paraplegia 42	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.367
ECC10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35251
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-1026-SM-4LMK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Cluster of actin-based cell projections	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.077
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.174617
GTEX-R55D-1826-SM-48FEF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K19536737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01533
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K24343201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2717
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Acute Myeloid Leukemia_LAML_TCGA-AB-2972-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stomach	GTEx Tissue Gene Expression Profiles 2023	1.0	1.6401
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6842
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1923
GTEx Esophagus 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	1.0	3.05025
VPS9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75877
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073119
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35503
ZC3H14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32969
GTEX-PLZ6-1326-SM-3NB24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64016
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.541
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	169.449
MBD3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80658
BRD-K98711518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29211
BRD-K69699301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15983
Perturb_4440_KO_Atoh1_SRP076034	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.65812
BRD-K59670689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13365
GTEX-SN8G-0226-SM-4DM6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33856
M059J	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-QDT8-0126-SM-48TZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907534
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.182886
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.302122
U20S	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.58224
BRD-K03599766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.50554
BRD-K26122955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52442
Brush border	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.123
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_12629_KD_CYGB_SRP388176	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.67274
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE250560_1_v_0_foxo1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XV7Q-0005-SM-4BRWI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KNS60	DepMap CRISPR Gene Dependency	1.0	7.49928
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.73376
BRD-K29684372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72129
familial hemiplegic migraine	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.557509
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6135
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.848995
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10319
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K41355409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30885
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.921946
Muscular coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
SAP30	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6826-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.993058
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
JAK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32545
GTEX-X638-0226-SM-47JZ9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910405
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11396
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3376-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
GTEX-S7SF-0826-SM-4AD4W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83667
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	80.0668
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.466498
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-OHPK-0526-SM-2HMJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97341
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03193
BRD-K14306031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19316
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
PMC4407272-elife06857s002.xlsx-501M_BRG1-MITF_ComDown-List-Ensembl_gene_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF491	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.18512
smoothmuscle_8b	HPA Tissue Sample Gene Expression Profiles	1.0	0.892441
Primary immunodeficiency disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
GTEX-RNOR-0926-SM-2TF56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834167
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43894
CYB561D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77223
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
EED	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18018
HNRNPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41982
ANKLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82511
HSF1_KD_GDS1733_752_human_HeLa cells - 2 Hour by siHSF1_1	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K65752097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.39651
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
Molybdopterin cofactor (Moco) biosynthesis adenylyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.697
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1583
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
PF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89749
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.486
GTEX-PX3G-2026-SM-48U1H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41512
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.48594
MEX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29703
GTEX-S32W-0326-SM-2XCBI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999961
symporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE173873_8_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I7-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WK11-0526-SM-3NB3O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.72854
FOXP1_01_209	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	2.93193
KPL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18082
chr22_32354332_T_C_b38	GTEx eQTL 2025	1.0	1.64824
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.143
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.81465
BRD-K18778674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07093
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K71839680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11774
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11497
GTEX-N7MS-0926-SM-2HMIZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5431
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048552
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.658818
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Gut	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.0
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07993
BRD-K30761927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25332
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37167
PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
SLC17A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62008
PTPRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04673
oltipraz	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87777
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043449
CCNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52615
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CRCGN017_MCF10A.WT.HP_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2506
PLAAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66179
H3K27me3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.635
cholinergic	GeneRIF Biological Term Annotations	1.0	null
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.60249
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HO-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.866569
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07993
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A6NJ-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
BRD-K22715231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43217
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.04005
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17333
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	1.0	1.81221
BRD-K94766933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70344
GTEX-T2IS-2226-SM-4DM65	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995839
SK-MEL-30	GDSC Cell Line Gene Expression Profiles	1.0	1.47525
Na+-dependent glucose transporters	Reactome Pathways 2014	1.0	null
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.991279
METTL21C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2402
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3327
ARX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30535
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6011-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-2526-SM-4DXUS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92555
NRF2 pathway	WikiPathways Pathways 2024	1.0	null
Glycinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.011
GTEX-TML8-1226-SM-32QON	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17779
KYSE30	DepMap CRISPR Gene Dependency	1.0	2.43923
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058259
BRD-K06117861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21141
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.4011
BRD-K08389897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.08107
PDLIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01665
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.77643
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.29399
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.245807
Duodenum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.838
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-QDT8-0926-SM-32PL2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.85664
GTEX-O5YV-2026-SM-2D7VS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
JHOM2B	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80245
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.5209
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
IZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.986476
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.1743
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-XUYS-0008-SM-47JYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
RVH421	CCLE Cell Line Gene CNV Profiles	1.0	2.06989
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904905
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.2221
BRD-K72591075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59452
POLR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14782
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04302
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75115
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05048
TUBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00301
CRCGN015_MCF10A_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.84265
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.70473