association	dataset	threshold value	standardized value
BRD-K35073835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07934
GSE128076_1_v_3_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118766_1_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160817_0_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198380_0_v_1_phgdh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09054
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216538_7_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZSWIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32433
GSE205730,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169571_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
YTHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32763
BRD-K25596713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58704
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37466
GSE110178_5_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216538_0_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.04462
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.36425
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE128076_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A91931411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11165
GSE238018_3_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K13211285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51086
GSE223008_6_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.42196
GSE145249_0_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203308_4_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K27723822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72435
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RPS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12774
GSE113106_3_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7673
GSE77108_4_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213588_9_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE196699_7_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	310.465
EEIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52577
BRD-K85567359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3183
GSE130383_2_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0031
BRD-K26431593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18839
Platelet distribution width	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.4699
NAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06327
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.74115
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE226249_2_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K34130171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14459
PMC8384902-mmc7.xlsx-190_ASCL1_Direct_activated-Unnamed_15_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205976,GSE205978_2_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE60837_2_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9168
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258343
GSE235945_1_v_0_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_12_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K34158806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40506
GSE100316_3_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE132759_4_v_0_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216273,GSE216292_0_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K13559806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7857
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K95815724	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6128
BRD-K07781811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02483
496100366_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0197
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6131
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76937233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.56532
ZNF765	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04337
CRCGN014_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35965
GSE220806_1_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
REXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00729
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC10592471-NIHMS1912771-supplement-2.xlsx-NR2F1-Ind-Upregulated_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K50510764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.5229
CRCGN012_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75052
BRD-K02395808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80947
GSE100316_7_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	362.783
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	176.327
GSE146612_2_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K25447152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48693
BRD-K77903467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73754
BRD-K36852613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.70299
GSE113329,GSE113335_2_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235066_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1639
GSE238018_3_v_5_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149943_2_v_0_cd8a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE209598_1_v_2_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	153.63
BRD-K60784115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26048
GSE231799_2_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K93023309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15744
BRD-K87658102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29891
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Corpus allatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.825
OBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07596
CRCGN011_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61465
MMP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7639
GSE97352_3_v_2_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE201657_0_v_1_ash2l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K74294292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01791
CLMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21661
BRD-K50822286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00497
GSE114992,GSE114993_0_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Vertebrate muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
DCTN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72191
BRD-K97183783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13665
Corpus cardiacum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
BRD-K75584297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06025
BRD-K35897342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02971
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K55877261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.281
GSE255680_1_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.28071
GSE229914_2_v_3_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K75410936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03565
GSE70935_3_v_5_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174383_1_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K37151525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59509
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.4015
BRD-K01699883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2392
GSE137818_3_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K48541282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8429
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.9116
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VA-06-DB75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200167
CRCGN014_HEPG2_3H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.378
BRD-K88080911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28891
BRD-K84688359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68816
GSE125211_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K40019775	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02155
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K44509164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27777
GSE148066,GSE157787_2_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Daphnetin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142539
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8173714-NIHMS1678410-supplement-Supplementary_Table_2.xls-OfficialIPEXsig-Supplementary_Table_2_-_IPEX_signature_genes_with_their_average_IPEX_HD_fold_change_in_Tregs_and_Tconvs_FOXP3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
furafylline	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.68934
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234605
496100618_PCx_probable Alzheimer's disease_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0903
BRD-K35103917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06019
GSE125157_1_v_0_piceatannol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Waist-to-hip ratio adjusted for BMI	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
BRD-K22246901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.58813
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE186810,GSE186813_7_v_0_furin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.062
GOSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10163
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5197
496100575_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13481
ZNF574	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16888
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2149
BRD-K75371115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08976
BRD-K98560805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17245
GSE202434,GSE202438_4_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE248858_4_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_DN3_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140937,GSE140938_0_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.9607
GSE120413,GSE120447_3_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A39521712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04931
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE96641_3_v_4_esrp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112365_0_v_1_sirt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149903_5_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Syntrophin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.546
GSE214514_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.1365
PMC8858874-NIHMS1764275-supplement-Supplemental_Table_2.xlsx-R1_SOX2_bound_genes_5000bp_6-9--Nearest_Ensembl_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196699_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	137.268
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02471
2376_DROSHA_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.673762
CRCGN016_MCF10A.TP53.M_24H:C10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17182
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146687_2_v_0_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K23647045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4511
PMC10542516-media-7.xlsx-EPC_siCTL_vs_EPC_SMAD1-5_Sample-symbol_SMAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE192689_0_v_2_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE113106_2_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_5_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
ECSIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54639
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.14065
GSE131649_6_v_1_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K84663394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20459
GSE198165,GSE198166_5_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3018
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.04335
BRD-K46155894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47231
Liver	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.09583
GSE224969,GSE224971_3_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178255_2_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Upregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K95251122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01976
GSE222103_0_v_1_ybx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184399_0_v_2_cnot1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127790_5_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180200,GSE180201_5_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.39719
GSE164529_0_v_2_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4051
IDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10542
GSE201239_3_v_2_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nuclear outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.345
PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-38-GPBP1_GPBP1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193541_1_v_2_nifurtimox_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10061014-Table5.XLSX-C_vs_LD-Table_S5c_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_DEX_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE229973_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE137144_5_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_JQ1_10µM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0097986
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166315_1_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Macrophage_Spleen_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9714459-DataSheet3.xlsx-Supplement_3A-1166_common_elements_in_MSC_and_Fibroblasts_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K38189757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80253
LRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39824
BRD-K11987248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06334
GSE198165,GSE198166_5_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TFAP2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	167.146
Tendon sheath	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K46311453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11746
SHISA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81203
GSE240896,GSE240899_5_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_6_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC2866657-pone.0010547.s003.xls-ERG_corr-Genes_correlated_anticorrelated_to_ERG_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226397_0_v_1_cystine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EFHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29363
GSE146982_3_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217873_1_v_2_nusap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K59709463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46353
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
GSE178255_5_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEp3_UP_NR2F1_ind_UP-NR2F1_Ind_UP_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_5_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:E12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.061
PMC10561055-mmc3.xlsx-LPS_T2-gene_name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15617
NPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34329
BRD-K34506374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49845
GSE120216_3_v_0_cbfb_human	RummaGEO Gene Perturbation Signatures	1.0	null
ASB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34291
GSE48812_11_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11221067-JCMM-28-e18520-s002.xlsx-Supplementary_Table_2-KLF2_KLF2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210885_0_v_4_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.505286
GSE139239_3_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228413_0_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE116810_5_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21999
PMC10803041-elife-86204-supp2.xlsx-Bulk_-_Snc-KD_in_HT-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ATP6V1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10425
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC3636213-pgen.1003459.s012.xlsx-Sheet1-KD_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9336541-Table_3.XLSX-C-vs-H6-L_filter_annot-Unnamed_18_HMX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K19946529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05571
BRD-K32986110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20858
GSE68155_1_v_0_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K48263613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36653
BRD-K15947051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18583
GSE85995_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.18685
GSE181003_3_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
WBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36262
GSE149442_1_v_0_gdpd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.109
GSE148066,GSE157787_5_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3833
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K02990757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17197
BRD-K77053153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03715
GSE65617_2_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K88195243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12663
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9964
H2AC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14424
CPNE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65285
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3098
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cyclocytidine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01346
GSE147943_7_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196699_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240027,GSE240030_5_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21695
BRD-K46623934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24761
GSE147366_1_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K05060234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0429
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111247_11_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1145
SDAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28705
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.9449
GSE143830_0_v_1_trex1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE120413,GSE120447_0_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K41423946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05506
BRD-K87854506	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20237
GSE184087_2_v_3_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE143847_2_v_3_inhba_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP2CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07474
BRD-K33385950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14014
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CWR22-Rv1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.611
PMC12240782-Table3.xlsx-Sheet1-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140997_4_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_3_SED-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE228162_2_v_5_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_11_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K76706127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.75181
GSE228413_2_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EIF4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30403
TNNC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16562
BRD-K94409042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0898
GSE140997_4_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K69768745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12608
BRD-K78983822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17124
b69	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.347
BRD-K37225211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49531
GSE197564,GSE198513_2_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178340_7_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K47348275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15263
BRD-K87617154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22293
BRD-K19911709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32443
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Amino acid transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.785
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44253
BRD-K34234678	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61932
BRD-K05475237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42168
GSE189609_1_v_0_hax1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-AA_up_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221327_4_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR2C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17678
GSE247862,GSE247863_4_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
5525_NDOR1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.625423
GSE100316_7_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.364
BRD-K40219231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74118
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE252864_0_v_3_smad4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	152.455
GSE131673_0_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE82032_3_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lymph node	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.164
GSE128730_3_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MCHR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71506
CRCGN012_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06038
CRCGN015_MCF10A.TP53.M_24H:F17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1634
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBC1D2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50245
GPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07985
GSE110268_2_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MIN-6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.393
BRD-M94053246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11522
KCNIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57677
BRD-K80888628	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96516
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.91651
GSE149903_4_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UBE3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11117
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE115763_3_v_1_klf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.80853
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.36287
GSE147210_2_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5083
GSE148692,GSE148695_5_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8724844-bt-30-1-98-supple2.xlsx-Hallmark_pathways-KLF2_KLF2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN008_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5654
GSE89018_11_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
INSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86836
GSE221327_5_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Synovium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_14_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3256
GSE189609_1_v_2_hax1_human	RummaGEO Gene Perturbation Signatures	1.0	null
fleroxacin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20613
GSE86507,GSE86509_0_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K55992427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0232
BRD-K19776718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90671
PMC8384902-mmc7.xlsx-190_ASCL1_Direct_activated-Unnamed_7_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151119_3_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K41574893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23091
GSE113221,GSE113968_6_v_1_prdm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
7648_SAP18_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.531959
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145311_0_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE218500_0_v_3_ruxolitinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K12181036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33271
Synovial tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE154464_1_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE224969,GSE224971_0_v_1_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K12347309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04051
TFB2M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75338
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE124375_13_v_0_chd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216538_7_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4823
BRD-K07497357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26163
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-AR-gene_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:B06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08485
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_6_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1378
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN017_MCF10A.WT.HP_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.171
BRD-K22474245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07211
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149035_1_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE197555_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6694122-41467_2019_11591_MOESM7_ESM.xlsx-a_GATA2_R361_Subclone_4_DEGs-SubGene_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6549
chr2_11158139_G_A_b38	GTEx eQTL 2025	1.0	3.15273
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE125025_2_v_3_lyl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227698_5_v_0_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:P08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.80415
BRD-K04269696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04522
6709_PPY_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.689217
PMC12685885-Table1.xlsx-Table_S9-Du_PanCancer_SOX6_TrsFib_SOX6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K15525634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14442
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.36626
GSE220693_1_v_0_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE212074_0_v_1_pus1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PAFAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45389
GSE94849_1_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148263_6_v_9_trim3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2894
GSE132408_1_v_3_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Spindle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
GSE199541_2_v_4_mbd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193258,GSE193259_5_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12216174-41598_2025_6356_MOESM13_ESM.xlsx-Sheet3-Supplementary_Table_3_Classification_of_amino_acid_AA_transporters_at_four_different_subcellular_localizations_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2143
LIVF001-029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12824
GSE101336_1_v_0_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Retrocerebral complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.771
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236416
BRD-K07390518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35877
GSE171837_1_v_2_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE246053_4_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_6_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K42091424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54228
RRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11216
7024_RAB32_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.57406
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198165,GSE198166_9_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEP3_UP_AA_UP-AA_UP_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	286.574
BRD-K55030454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00041
BRD-K10089296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69916
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K31616862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11827
novobiocin-na	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62101
BRD-K45811188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82681
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K48427969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4555
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K37912617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04008
BRD-K79887735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.71789
GSE131161_2_v_6_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_6_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8143797-elife-62857-fig4-data2.xlsx-TAZ-CAMTA1_ChIP_RNAseq_merged-ENSEMBL_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
canthaxanthin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34342
GSE48812_0_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE96641_5_v_2_esrp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K39422601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04342
GSE216538_0_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE87412,GSE92423_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K62418408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12924
BRD-K18304318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05571
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152441,GSE152442_1_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K31682048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0479
GSE111247_14_v_12_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GMPPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00028
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE181959_1_v_0_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE229102_1_v_0_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.043
GSE133683_3_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41263
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:F08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14743
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7128
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pituitary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.07038
RD-50-EO07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.274612
1197_CARS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.754043
BRD-K50435683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55913
GSE205163,GSE205164_9_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256109
3447_GNL3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.631154
GSE77178_2_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K81960205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41861
GSE117730,GSE117732_0_v_2_apobec2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CCDC88C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24727
GSE101537_4_v_2_neurog3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	218.472
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1711
GSE128333_4_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
C3orf18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16122
BRD-K66868536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2062
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206779_4_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K85352360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49524
CRCGN017_MCF10A.WT.HP_24H:P09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3418
ZC3H10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53954
PMC12216174-41598_2025_6356_MOESM13_ESM.xlsx-Sheet1-Supplementary_Table_3_Classification_of_amino_acid_AA_transporters_at_four_different_subcellular_localizations_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.4235
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K84170953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97513
GSE152666,GSE152668_2_v_1_carm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203308_1_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.315
Gonadal mitotic phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE189859,GSE189861_0_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101546_3_v_4_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K39913135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02516
2495_EFHD1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.841472
GSE130383_1_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111247_2_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K64165176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45903
CRCGN010_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7034
GSE178255_2_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.135
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K48140215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67892
BRD-K37015376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76908
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79718
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.39781
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.6598
CRCGN017_MCF10A.WT.HP_24H:N23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52495
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STOML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42553
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Macrophage_Brain_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE186810,GSE186813_7_v_0_furin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
6794_PRPF38A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.549454
301_ANAPC10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.700654
BRD-K01022714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6824
BRD-K81575721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29064
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_LF_species_not_found_in_common_genes_of_R_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0806
BRD-K62625902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06437
GSE217363_4_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201381_0_v_1_bhlhe22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K95877349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.63394
BRD-K34028745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24285
GSE178255_5_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178340_7_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
7581_RSU1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.650287
CRCGN008_HEPG2_24H:A06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05145
Uterus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.211
BRD-K32037893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45575
CCT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13074
BRD-K62794454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08326
DHX36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.392
GSE240896,GSE240899_10_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.062
GSE118766_2_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195663_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE129725_1_v_5_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CD164L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16191
GSE100863,GSE100864_3_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3371315-NIHMS350140-supplement-13.xls-MCF7-T47D-SK-453_Up_Common_xls-Supplementary_Table_6_Luminal_Signature_Genes_increased_in_all_four_cell_lines_MCF7_T47D_MB-453_SKBR3_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.38109
PMC8752721-42003_2021_2991_MOESM4_ESM.xlsx-Fig3_E2F2-gene_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K23666684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.77485
SPCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1908
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.16834
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	190.178
CRCGN017_MCF10A.WT.HP_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.43965
GSE151612_0_v_3_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Golgi-associated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.249
7524_RPS3_P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.653197
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE116810_5_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE86507,GSE86509_7_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K57228212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42182
GSE151612_0_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.5676
GSE165122_0_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
t67-small-intestine_female_1w	MoTrPAC Rat Endurance Exercise Training	-1.0	-1.83505
GSE169152_5_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE100863,GSE100864_2_v_1_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K51843685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66243
GSE152432_3_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137144_5_v_6_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149035_2_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4388
PMC7203476-Table_2.XLSX-MI_treat_vs_control-Unnamed_0_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K77504251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27859
CA-25-LR28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.274684
BRD-K68470956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69708
GSE168473_0_v_1_isoniazid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5505
BRD-K19042305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89583
OGFOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21085
GSE223334_3_v_0_bcl11b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64262
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4943
PMC10082046-41467_2023_37049_MOESM7_ESM.xlsx-Sheet1-Supplementary_Data_4_Genes_upregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
IK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18315
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE70935_1_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.7323
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE203308_7_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K97994060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49521
BRD-K19523037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6221
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE186767_1_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K82764092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84733
GSE184356_3_v_0_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE141624_3_v_0_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.4716
GSE158458_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K47707657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.66805
GSE151090_5_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K92904754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30256
Apical cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
BRD-K91341416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02345
GSE221577_4_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178714_1_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GB-46-CK08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252431
BRD-K27049948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31257
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	222.05
BRD-K31606237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03717
GSE135439_0_v_1_pax5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PIWIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07317
GSE242290_1_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147056_4_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114258_1_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.289
GSE146982_3_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K77591784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85076
SLFN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14223
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	2.87502
GSE216043_7_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.56867
GSE127790_11_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203308_7_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2348
CRCGN015_MCF10A_48H:E21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12536
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K23326916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2032
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-Aza_atRA_DE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165647_2_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211955_1_v_0_jmjd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9143
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_19_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148066,GSE157787_0_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LIVF001-027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.44514
PMC9691391-7945884.f3.pdf-41-ENSG00000166261_ZNF202	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K69918256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0463
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC5113908-pone.0166185.s004.xlsx-Supp_1-Supplementary_Table_1_mRNA_expression_correlates_with_STAT3_phosphorylation_for_1279_genes_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bleomycin-sulfate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.81814
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130383_1_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.38277
GSE169571_3_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10561055-mmc3.xlsx-LPS_T2-hgnc_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_3H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5749
NOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.08746
BRD-K78847404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0904
Zymogen granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.628
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2929
GSE77108_0_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE249146_2_v_3_dusp6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ODAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17583
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.13759
PMC11465047-mmc3.pdf-2-ZBTB6_ZBTB6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE115395_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K77901830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41256
GSE178255_2_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227698_2_v_1_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70322
BRD-K95935249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16816
GSE178255_5_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K61533770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14373
BRD-K32718105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01431
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-Partitions_EPC1-PHF1-FLAG-Unnamed_20_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K18139667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.32827
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.3477
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K10092312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01852
GSE139540_4_v_1_menadione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE223008_0_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07037
BRD-K14199536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68319
CLSPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21843
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7001
GSE125219,GSE125221_3_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K79829201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89504
4147_INTS2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.65607
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.8815
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226544_1_v_0_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE198165,GSE198166_9_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220520_6_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48657
GSE202434,GSE202438_3_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE224969,GSE224971_0_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K65250438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09225
GSE213228_2_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Golgi trans cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.47
WC-59-RG09_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206706
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.30288
5732_NOL10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.643944
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.60563
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
CCNYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24261
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-CCRF-CEM_EV_vs_ectopic_TET2_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
Esophagus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.054
GSE109140_2_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE141624_3_v_6_cocaine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_15_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE153189_2_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K70681322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06988
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_upregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
CYB5R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42631
CRCGN016_MCF10A.WT.HP_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6011
BRD-K88351048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.58786
BRD-K14719962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.77771
AR4-2J cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.612
SMG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49188
1464_CDYL_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.612684
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRKCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31583
GSE114992,GSE114993_0_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE100316_0_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Golgi stack	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.034
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE246195,GSE246305_4_v_5_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K48260102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19646
GSE129725_4_v_0_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE155305_3_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE122101,GSE122103_0_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE67266_7_v_3_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.1708
GSE145215_2_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203308_7_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7532671-thnov10p10957s2.xlsx-Table_S6A-Table_S6A_Differentially_expressed_genes_DEGs_in_DDX5_KD_versus_WT_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56506
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8175556-42003_2021_2140_MOESM6_ESM.txt--KLF2_KLF2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE215086_3_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K75206417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01864
GSE161846,GSE161849_4_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	1.0	null
5165_MPHOSPH8_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.573915
BRD-K41513047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.116
GSE227698_5_v_3_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08067
GSE98755,GSE98756_1_v_0_fbxl19_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210885_0_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SH3BGRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16282
GSE119603_1_v_0_oxaliplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.50049
U2AF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.54
GSE202434,GSE202438_12_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147210_3_v_4_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_3H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52957
BRD-K45380779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03519
GRIN3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67309
GSE182680,GSE182683_0_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205316,GSE205317_0_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PNISR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73249
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
10623_ZNF774_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.901669
BRD-K16064200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25986
NDUFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01003
GSE100316_5_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10894266-42003_2024_5898_MOESM9_ESM.xlsx-EPC_siCTL_vs_EPC_SMAD1-5_Sample-gene_id_SMAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE118794_2_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6566
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K73573090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09767
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Myosin XVI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.955
GSE185944_2_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10061014-Table5.XLSX-C_vs_L-Table_S5a_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K81144230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02141
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33687
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203308_15_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K28932578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30181
BRD-K30436657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05654
BRD-K01780082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05461
9420_TUBB_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.642518
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138815,GSE138817_0_v_2_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K96295480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28561
GSE180200,GSE180201_5_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8283158-mmc2.xlsx-TCF4_Glut-Gene_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE188870,GSE188871_1_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18555
8645_TACC3_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.514098
trans-Golgi network transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.148
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	126.956
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.944647
Stomach	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.55895
PMC9974104-jci-133-159940-s019.xlsx-GT3-INCP-GATA3_co-bound_genes-Gene_Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8405683-41419_2021_4120_MOESM2_ESM.xlsx-Sheet1-Table_S2_MYCN-responsive_gene_list_1_5_fold_p_0_05_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8481886-Table_2.xlsx-A_subsets-common_MSC_AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
MLXIPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01455
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE141328_1_v_0_rock2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06466
GSE232631_5_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K95323755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4311
CLINDAMYCIN-PO4	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3206
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	1.0	2.23018
BRD-K37527074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72482
GSE220520_6_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
3086_FIP1L1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.810197
HA-22-CY42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.208886
BRD-K02681754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12016
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.17438
GSE110178_1_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-h-Classification_of_camel_SON_basal_genes_-_transporters_SON	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K84706257	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34742
FZD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46782
CRCGN013_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4818
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3563
BRD-K06344882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82798
GSE89018_6_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K72773830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29651
GSE199081_0_v_1_insr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131649_2_v_1_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K80239721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14387
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPS6KA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13336
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205556_2_v_0_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K04104496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44517
GSE213588_8_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	138.157
PEG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05046
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE124375_10_v_9_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.34123
BRD-K45037973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09371
4758_MAGEA12_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.612033
NUBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00056
GSE233679_6_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221327_5_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A82843133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.102
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Hereditary sensory neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.248
GSE147876,GSE147877_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213588_9_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SERINC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69445
BRD-K04116560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3823
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE168676_0_v_1_dach1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K76420749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21967
TMEM30B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24445
BRD-K41026056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16856
BRD-K23591737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17768
PMC8384902-mmc6.xlsx-DEG_ASCL1_3TF_shared-GeneSymbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE116810_2_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1672
GSE149000_2_v_0_cyp3a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7934233-13059_2021_2293_MOESM8_ESM.xlsx-Fibroblast_ATF1-gene_ATF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE186620_0_v_1_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142430_3_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE82032_3_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K81956993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52445
GSE171837_0_v_3_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE190947_2_v_0_xbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K55692246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92025
6855_PSMB6_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.596209
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	176.3
BRD-K44921931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9299
BRD-K27882424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07031
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE151090_0_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11237033-41419_2024_6873_MOESM3_ESM.xls-Supplementary_Appendix_2-KLF2_KLF2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K06177900	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36985
BRD-K70198986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28967
GMCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16498
BRD-K05657319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12676
GSE184884_4_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8384902-mmc7.xlsx-190_ASCL1_Direct_activated-Unnamed_1_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN010_HEPG2_24H:J23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42194
PMC9013128-NIHMS1795992-supplement-4.xlsx-SKmel147_ARID2_KO_Upregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
Waist-hip index	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.939794
GSE152441,GSE152442_6_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157777_1_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K66852478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.238
GSE178255_5_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K63008302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61106
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Vermiform appendix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.109
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.50835
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	233.752
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.4204
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6141
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-Gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ZHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12408
GSE202434,GSE202438_9_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN017_MCF10A.WT.HP_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.31205
GSE208254_4_v_5_irf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K81277520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8353
GSE198165,GSE198166_8_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6772115-JCB-120-18332-s003.xlsx-TP53-Unnamed_1_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CDK12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60087
RWDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35911
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE223008_7_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210580_5_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE89767_2_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TELO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14961
GTEx AdiposeTissue 20-29 vs 30-39	GTEx Tissue-Specific Aging Signatures	1.0	4.84799
GSE161771_0_v_1_secretin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100404_PCx_possible Alzheimer's disease_TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.26664
BRD-K94452277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88179
GSE73561,GSE73563_0_v_1_mef2c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89018_1_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K12342133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30942
7422_RPAP1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.616482
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
HC-01-FD24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.344975
COPZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36343
PMC11563688-jci-134-173448-s017.xlsx-EC2-gene_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
GSE208254_3_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196699_7_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TF-04-RX73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.237879
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102505_4_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DPYSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0589
BRD-K33371292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35595
BRD-K30292003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17328
AC-83-LN99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27996
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IQSEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12203
GSE82104,GSE82299_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE242083,GSE242098_3_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193402_0_v_3_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MA-58-RR04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214038
GSE210101,GSE210114_11_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2206
GSE173997_3_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE126776_2_v_1_pelp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Connective tissue	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NLGN4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75842
GYG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83873
BRD-K39587434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21634
CRCGN012_HEPG2_24H:O17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02396
GSE178255_3_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE137818_5_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_0_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7008
Gut microbiota (bacterial taxa, hurdle binary method)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	393.787
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5455
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10290283-biol-2022-0622-sm3.pdf-408-FOXJ2_FOXJ2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K43896262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07278
GSE173262_2_v_5_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S2.xlsx-S2B_in_vivo_shared-Suppl_Table_S2B_shared_genes_between_RCAS-YAP1-MAMLD1-dR3R1_RCAS-YAP1-FAM118B_RCAS-YAP1-TFE3_in_vivo_tumors_RCAS_mouse_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6414
GSE80098,GSE80366_0_v_6_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59402
MFGE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50723
GSE171486_4_v_6_ddx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE126463_1_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K59434830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13582
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_6_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K16228393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35534
CRCGN015_MCF10A.TP53.M_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8613
PMC8858874-NIHMS1764275-supplement-Supplemental_Table_2.xlsx-R1_SOX2_bound_genes_5000bp_6-9--Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180800,GSE180801_0_v_5_tex10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.5515
CRCGN014_HEPG2_24H:C03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2678
BRD-K52721673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10183
5005_METTL4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.512156
9655_USP39_P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.526389
GSE165579_0_v_1_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BE-27-RQ61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236083
t67-small-intestine_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	3.82345
BRD-K62714735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.32599
GSE100316_3_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K21466747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.39402
GSE202434,GSE202438_8_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60154
GALNT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59607
GSE128076_2_v_3_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain - Cerebellum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.37014
PMC7934233-13059_2021_2293_MOESM8_ESM.xlsx-Fibroblast_HOXC6-gene_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE113106_3_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75235
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7638
A549_AR-42_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126907
GSE180200,GSE180201_3_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110178_1_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120413,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199899_1_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5303304-13073_2017_407_MOESM4_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_2-Table_S3_Genes_differentially_expressed_by_24h_RA_and_48h_Dox_co-treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K27083306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14155
KIAA1143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16527
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.274162
BRD-K05496005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66864
BRD-K41684304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29767
BRD-K21206585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1509
GSE110178_2_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K26620362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06263
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.18505
NAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13567
GSE205316,GSE205317_0_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K76329122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80705
GSE165174,GSE165175_0_v_1_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3637
CRCGN011_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1084
Hematopoietic stem cell_Bone marrow_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
BRD-K16247913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.6136
PMC12381255-41389_2025_576_MOESM3_ESM.xlsx-Differentiated_SRCAP-1879-Gene_SRCAP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240896,GSE240899_2_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.28585
BRD-K01691949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18605
GSE220520_6_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.18376
GSE148510_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE71491_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K40960913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22204
GSE221327_5_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_0_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3462
GSE130383_2_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBC1D24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01123
Perivitelline space	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.669
BC-26-LE04_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.256672
GSE180200,GSE180201_15_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203308_9_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE240439_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9513
CRCGN011_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6823
2339_DPCD_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.553803
GSE152432_1_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63728
RPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68985
BRD-K37975989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24436
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60002
BRD-K12012973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07267
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.383622
Golgi cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.499
GSE239844_4_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
569_ASB8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.852283
BRD-K99172965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40777
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FAM72D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30856
PMC6225799-annrheumdis-2018-213524supp003.xlsx-Activated-state-LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4091
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217776,GSE217829_2_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.678
GSE184399_0_v_3_cnot1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142684_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225684_0_v_2_tfap4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K07988588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22672
BRD-K67592986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42613
GSE146982_4_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RDH14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84762
BRD-K48069820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99267
GSE128730_3_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.062
MRPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39965
PMC10561055-mmc3.xlsx-LPS_T0-hgnc_symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152441,GSE152442_7_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE203308_6_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3898078-1471-2164-15-40-S1.pdf-66-POU1F1_POU1F1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A71933035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34697
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SGCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04184
GSE88819_3_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ileocecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.109
GSE195568_6_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K89179622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4252
CRCGN014_HEPG2_3H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0954
BRD-K93459372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05877
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1c-List_of_1682_genes_differentially_regulated_by_GLI1_FDR_0_1_GLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE77108_3_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K71015709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87952
BRD-K61354849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20287
9311_TRMT44_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.579321
DPP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09401
GSE94849_7_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K75136523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04573
BRD-K02927989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00505
GSE168807_6_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-61-BE07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275868
GSE208254_4_v_2_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-493-ENSG00000186487_MYT1L	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K53228569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8527
PMC8143797-elife-62857-fig4-data2.xlsx-TAZ-CAMTA1_ChIP_RNAseq_merged-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125782_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN014_HEPG2_3H:J03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1936
RNF122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69881
GSE129293_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-44-MYT1L_MYT1L	Rummagene Transcription Factor Associations 2026	1.0	null
GSE183335,GSE183351_1_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178255_1_v_0_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165579_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K28195874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05619
GSE232564,GSE232566_0_v_2_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.67292
BRD-K20138377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07779
GSE240896,GSE240899_2_v_4_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_TAZ-CAMTA1_vs_EV-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226316_0_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K30288714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00686
GSE152441,GSE152442_6_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210885_0_v_7_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TMEM185A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39403
GSE232558_0_v_1_fbxl12_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K61431055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.90385
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.38626
496100442_PCx_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21342
GSE209938_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
oltipraz	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56731
delavirdine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23432
Trabecula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.661
BRD-A89038047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.611
GSE129244_0_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184087_0_v_3_tert_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE255432_4_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
AC-41-IB85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207349
496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.61508
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.16067
BRD-K31230200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33116
GSE152432_1_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10561055-mmc3.xlsx-LPS_T0-gene_name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PARP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05672
GSE180200,GSE180201_12_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89154_1_v_0_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04009
GSE180200,GSE180201_5_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE190384,GSE190386_1_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
Mitotic fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
BRD-K55187504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06656
GSE217105_0_v_1_gemcitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE75976_3_v_6_abl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE118794_0_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K69387464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32913
GSE240027,GSE240030_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K26361872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4111
GSE218356_1_v_0_cited1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE190235_0_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217873_1_v_0_nusap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K36099605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05453
GSE100316_0_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153124_4_v_0_dsg2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
INTS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09467
PMC6357748-aau9223_Table_S1.xlsx-CD4_T_-_LPS-Unnamed_0_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226249_0_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56413
GSE149621_0_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227891_5_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K81665173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53923
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K41504921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47079
GSE89767_1_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7788918-13058_2020_1379_MOESM2_ESM.xlsx-S9-S9_limma_voom_differentially_expressed_genes_ESR1_depleted_recurrences_vs_matched_primaries_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE101537_1_v_3_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41177
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE154767_2_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133691_1_v_3_lgr5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10542516-media-7.xlsx-EPC_siCTL_vs_EPC_SMAD1-5_Sample-gene_id_SMAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K20846358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53389
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.3972
GSE209898,GSE209899_0_v_1_flcn_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.1096
OB-06-WW76_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237179
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.9381
BRD-K62555617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33185
BRD-K34595193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97827
BRD-K23162004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85141
GSE149035_1_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K03902845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0054
GSE215086_8_v_6_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K85907501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44276
CRCGN016_MCF10A.WT.HP_24H:D04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3579
GSE171712_0_v_1_scgb1a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11906354-41588_2025_2087_MOESM4_ESM.xlsx-ST12-Unnamed_3_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226316_3_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200352_4_v_8_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K02811477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60265
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LIVF001-007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19784
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K44427106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01835
PMC10684125-cm9-136-2712-s001.xlsx-Sheet1-KLF2_KLF2	Rummagene Transcription Factor Associations 2026	1.0	null
CCZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12903
GSE201361_0_v_1_mpst_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Alimentary canal	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE180200,GSE180201_2_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3022822-1471-2164-12-11-S10.XLS-Suppl_7_newLN229_SOX2_KO_MOCK_2-Unnamed_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.93798
CRCGN016_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6869
BRD-K41972460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.77838
PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K05002317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26491
MXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01701
PMC11684804-jci-135-174981-s193.xlsx-DESeq2_pseudobulk_AA_Ag_vs_Pre-Gene_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE137818_2_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_14_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4905481-oncotarget-07-11397-s002.xlsx-Pinin_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K66189308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19894
GSE121866_0_v_3_six4_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3356
GSE202434,GSE202438_4_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158969_1_v_2_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
Gastrointestinal tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.1106
BRD-K93923246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47188
GSE180277_0_v_1_bach2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
1651_CLEC2L_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.658901
BRD-K41645779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12776
PMC8567280-EMBR-22-e53014-s007.xlsx-Sheet1-Nearest_genes_to_BAZ2A-bound_C2-Enhancers_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE239844_4_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EC-82-LV30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.220706
UTP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31829
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE189772,GSE189773_3_v_2_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K32173944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76427
NDRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8666
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE165548_2_v_8_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BA-59-EN38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.207456
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K97729706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12584
CRCGN011_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.6237
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nr1h3::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.7336
PMC10894266-42003_2024_5898_MOESM9_ESM.xlsx-EPC_siCTL_vs_EPC_SMAD1-5_Sample-symbol_SMAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K17749779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30765
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K58826761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25835
GSE209898,GSE209899_0_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35142
C19orf44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3044
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K14037093	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21163
GSE67266_7_v_4_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K70673311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01149
CRCGN010_HEPG2_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1846
SECISBP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58634
CRCGN011_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50065
BRD-K23118252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37092
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE232558_0_v_2_fbxl12_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7300082-41598_2020_66556_MOESM11_ESM.xlsx-Supplementary_Table_10-KLF2_KLF2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE93309_1_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.062
GSE171177,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147626_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
U2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54329
CRCGN008_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
BRD-K22314621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85364
GSE117042_0_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE159148_0_v_1_sdc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6604
BRD-K97255584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02147
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.27713
BRD-K21568472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22129
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210951_1_v_0_islr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6137307-mmc2.xlsx-STAT2-IFNa-Table_S1_STAT2-IFNa_Related_to_Figures_1_4_STAT2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE91015_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H358 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_DOWNREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12343830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72189
GSE178255_3_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K59185421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49246
GSE110178_2_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE201217_4_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145445,GSE145454_0_v_1_cop1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128076_2_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCall_EPC1-PHF1_FLAG_K562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196699_7_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153189_2_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240439_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8224457-MSB-17-e9760-s005.xlsx-C_Ctrl_v_HMGB1-KD_IMR90-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233679_6_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193685_2_v_3_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE218378_1_v_0_pbx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Tendon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE205163,GSE205164_5_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240896,GSE240899_3_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A64374397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55958
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16424
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1369
BRD-K75143842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	6.69478
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
6870_PSMD2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.06736
NFIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00838
BRD-K77004285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15558
GSE201042_2_v_4_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K26586614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49643
CRCGN012_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.30956
GSE183316,GSE183317_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12297
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.13315
BRD-K85235446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39214
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.08195
GSE165647_5_v_4_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K33760789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21404
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1175
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154081_1_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PRCC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53395
GSE208254_3_v_1_irf8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14556
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273644
GSE144838_1_v_5_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE126345_11_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8033524-EMMM-13-e13162-s004.xlsx-d_GREAT_on_NFIB_bound-genes_HF-Unnamed_0_NFIB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE103068_0_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DLG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17817
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.83665
GSE124304_1_v_0_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K91239327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2486
GSE77178_5_v_3_ccnd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06082
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.7758
BRD-K41779994	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79233
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	210.541
GSE175787_13_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110178_5_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.6686
CRCGN012_HEPG2_24H:J05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49195
PMC9424213-41467_2022_32537_MOESM6_ESM.xlsx-siHNRNPK_cyto-DEGs_for_hnRNPK_KD_cytoplasmic_RNA_of_HeLa_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0626
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZSWIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14457
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K10987837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02311
GSE161295_4_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12216174-41598_2025_6356_MOESM13_ESM.xlsx-Sheet2-Supplementary_Table_3_Classification_of_amino_acid_AA_transporters_at_four_different_subcellular_localizations_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-Unnamed_4_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE100316_0_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_4_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228413_4_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K87530935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78708
BRD-K02073410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02401
CRCGN015_MCF10A.WT.HP_24H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.50825
GSE129389_0_v_4_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152441,GSE152442_0_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K40814141	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84852
GSE227698_2_v_4_g0s2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	176.167
LIVF001-013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36834
FTSJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00945
GSE244940_0_v_1_edf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.334311
BRD-K77465015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10241
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.0786
BRD-K89832379	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20417
INTS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20878
BRD-K88278778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04259
BRD-K11428617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05861
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0639
GSE169571_3_v_4_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	201.038
GSE153341_2_v_3_atf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0132
BRD-K09615275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2908
Stomach	GTEx Tissue Gene Expression Profiles 2023	1.0	1.02998
BRD-K34206995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34046
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE70935_3_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
craniofacial-deafness-hand syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
GSE213588_9_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE224004,GSE224005_0_v_8_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140445,GSE140448_1_v_0_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154464_1_v_3_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147283_1_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151090_0_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K26636241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02729
GSE162384_1_v_0_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
5599_NELFB_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.553059
TYRO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81953
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE128730_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38982
CHMP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70365
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K47482563	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36423
GSE233679_5_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7672319-mmc3.xlsx-Senescence_MSigDB62-ONGUSAHA_TP53_TARGETS_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205163,GSE205164_3_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE240896,GSE240899_10_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
UCHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47679
CRCGN015_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34761
PMC6694122-41467_2019_11591_MOESM7_ESM.xlsx-c_GATA2_R361_whole_sample_DEGs-Gene_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152432_6_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_9_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PHB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83187
GSE203308_14_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102505_1_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28528
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE89018_10_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K95125640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13171
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270221
SH3BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12807
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7429792-40104_2020_487_MOESM3_ESM.xlsx-MSC_enriched_miRNA_target-NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50876
YME1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10654
7538_RPS8_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.528375
GSE235682_1_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_1_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ADCY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30331
GSE193900,GSE193905_1_v_0_pura_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174383_6_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
7141_RBBP5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.612712
Testis	GTEx Tissue Gene Expression Profiles 2023	1.0	1.21741
GSE137818_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102486,GSE102490_1_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102505_6_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.758
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13916
BD-96-HO33_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230417
GSE179880_1_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K99338550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26517
CRCGN017_MCF10A.WT.HP_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62555
BRD-K53293966	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66413
GSE144838_1_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178255_3_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ring gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.0
GSE129244_3_v_5_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE190384,GSE190386_2_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
XC-81-LR46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.210116
SOX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16206
BRD-K65887908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.2799
GSE248045,GSE248046_4_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K56916066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28864
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN014_HEPG2_3H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.108
GSE118794_2_v_1_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BB-74-RX30_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229101
GSE248935_1_v_0_cd14_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193402_0_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10933434-44319_2024_69_MOESM1_ESM.xls-HRV16_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131161_2_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30245
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112714_2_v_0_ctnnb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224793
BRD-K16838397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12196
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.392415
GSE203655_0_v_1_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K94647035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02538
BRD-K25718630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.82899