association	dataset	threshold value	standardized value
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58377
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10792
CNOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18515
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4228
K562_Tie2 kinase inhibitor_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0181622
MCF7_BMS-536924_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.012774
NRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50448
PMC3964217-oncotarget-05-417-s001.xls-Supplemental_Table_3-GABPA-bound_promoters_GABPA	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Andarine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140244
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5117
IRF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46183
POM121C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42371
PMC5059470-ncomms12992-s6.xlsx-CRS-NOCRS-Supplementary_Data_5_Integration_Frequency_in_cirrhotic_CRS_and_non-cirrhotic_no-CRS_Tumor_Samples_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
K562_AMG-900_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0179773
K562_MC1568_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162793
LAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21863
K562_RG108_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0198062
IFITM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09854
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8276
PMC2866657-pone.0010547.s003.xls-ESE3_corr-Genes_correlated_anticorrelated_to_ESE3_EHF	Rummagene Transcription Factor Associations 2026	1.0	null
IWS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10456
K562_Mocetinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0125695
SRSF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00751
K562_Decitabine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0173693
CSAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33985
PMC11602576-mmc11.xlsx-ST12-Table_S12_Output_of_mash_model_of_milk_and_GTEx_eQTL_effects_Related_to_Figure_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2174
A549_Capecitabine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015081
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8512
MCF7_Cimetidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0198043
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8881
PMC9314667-Table_1.xlsx-Regulons-XBP1_XBP1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC3290552-pone.0032232.s006.xls-MUC4-KD_vs_Mock-Unnamed_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TCL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05902
A549_Thalidomide_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173694
K562_WHI-P154_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143422
MCF7_Ki16425_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.025881
K562_Altretamine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146539
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2807
496100401_FWM_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05321
A549_EED226_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150057
MCF7_Aurora A Inhibitor I_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0195459
K562_Amisulpride_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0185689
K562_Fedratinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0185943
A549_Meprednisone_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.011977
A549_Azacitidine_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151599
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETV4_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
KCNMB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61584
POLR2H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11206
K562_Maraviroc_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0186744
PMC6684323-NIHMS1532201-supplement-Table_S6.xlsx-LPS-Sup_Table_6C_Delta_PVE_among_PopDE_genes_LPS_PopDE_FDR_0_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_DOWNREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Obatoclax Mesylate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01187
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6465
K562_AICAR_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014717
PMC7468443-Data_Sheet_2.xlsx-DEG_6h_LPS-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Selisistat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152718
CUL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27238
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
A549_ITSA-1_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0114003
SEZ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05135
K562_SL-327_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148278
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.763
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1977
K562_Cimetidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0184764
MCF7_Tozasertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127446
PMC7316257-pone.0233899.s011.xlsx-AR_regulated_genes-genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7338542-41389_2020_247_MOESM6_ESM.xlsx-BRN2_2_of_3_DOWN_48_h-Symbol_POU3F2	Rummagene Transcription Factor Associations 2026	1.0	null
R3HDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48764
PMC12629827-mmc8.xlsx-DDR2_KD-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Fulvestrant_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0220266
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0041
A549_Belinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0127712
TOMM34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07838
K562_S3I-201_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168074
K562_MLN8054_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161974
A549_Nilotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0133603
MCF7_Glesatinib(MGCD265)_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0241138
A549_Resveratrol_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182116
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25444
K562_Fasudil_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161433
PMC8758144-elife-74272-supp3.xlsx-AP2_REP1-GeneName_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Entinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140051
PMC8384902-mmc7.xlsx-163_NKX2-1_ChIP_3TF-KD-Unnamed_7_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RPAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88573
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9069
MCF7_Streptozotocin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178816
COMMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3535
PEX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00407
A549_PF-3845_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161593
MCF7_Entacapone_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0231471
K562_Veliparib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0303663
NHLH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0646
K562_Ramelteon_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161655
A549_2-Methoxyestradiol_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151796
MCF7_Aminoglutethimide_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0187776
K562_ENMD-2076_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136476
K562_Carmofur_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0233732
MCF7_AG-14361_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130708
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7303
K562_Fulvestrant_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0233428
ADRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3124
PRPF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09514
MCF7_BMS-911543_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144026
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6746
PMC11263707-41419_2024_6896_MOESM4_ESM.pdf-13-CREB3L4_CREB3L4	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Temsirolimus_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0180662
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9804
K562_Nilotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0118116
A549_Filgotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0181784
K562_Roscovitine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136293
COA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11797
K562_Andarine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174716
CDC23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07164
PMC5527282-ncomms16041-s3.xlsx-M_LPS_-_gene_signature-Supplementary_Data_2_Full_gene_list_of_M_LPS_-_signatures_as_defined_in_figure_3_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
DDX31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0939
UBFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76002
MCF7_MK-0752_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164559
A549_Anacardic Acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0250756
PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
CTNND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26095
CCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85161
A549_SGI-1776 free base_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0218144
PMC11627398-pone.0315219.s005.xlsx-MTF1-symbol_MTF1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.3449
A549_Tazemetostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0129041
PPIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17391
MCF7_Thalidomide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0208789
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.1926
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8125
NOP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03149
A549_Aurora A Inhibitor I_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0121387
GDF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17876
MCF7_MK-5108_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169778
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.86965
K562_Cerdulatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176703
AGAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21803
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5815
MCF7_Meprednisone_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156355
PMC8481886-Table_2.xlsx-A_subsets-common_MSC_AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4648
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.2278
MCF7_PD98059_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0184149
SLIRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44164
K562_ENMD-2076 L-Tartaric acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0181905
HRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70084
VPS28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05373
TBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1225
K562_Lenalidomide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146344
K562_Alendronate sodium trihydrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0198875
MCF7_ZM 447439_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132945
A549_Entacapone_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167386
A549_PF-3845_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0202301
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4975
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6189
MCF7_Vandetanib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015718
K562_Flavopiridol HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0174442
NCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78783
K562_Tanespimycin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0211512
A549_Alvespimycin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155491
IPPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38631
496100593_TCx_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16004
PMC5113908-pone.0166185.s004.xlsx-Supp_1-Supplementary_Table_1_mRNA_expression_correlates_with_STAT3_phosphorylation_for_1279_genes_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
SEC61A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81406
VPS37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10644
PMC2263127-pone.0001816.s001.xls-E2F3_down_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_UNC0379_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0199882
DCAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36576
A549_MC1568_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134958
CTDSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39836
PMC11531655-MCO2-5-e754-s001.docx-0-IRF7_Regulon_5_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12375500-41388_2025_3449_MOESM1_ESM.xlsx-DBP_up-gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Nilotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0133145
PMC7616986-EMS181817-supplement-Supplemenatry_tables.pdf-287-ZNF480_ZNF480	Rummagene Transcription Factor Associations 2026	1.0	null
DGCR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45918
K562_PF-3845_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0185273
K562_Cerdulatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0239545
K562_Vandetanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0216137
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9295
PSMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49819
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2885
A549_AG-490_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158924
MCF7_Capecitabine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162142
MCF7_2-Methoxyestradiol_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147387
PMC9942321-12916_2023_2766_MOESM1_ESM.xlsx-S5-Supplementary_Table_5_Differentially_expressed_genes_DEGs_distributed_per_SOM_profile_based_on_Euclidean_distance_GRHL3	Rummagene Transcription Factor Associations 2026	1.0	null
PAQR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01557
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7198
PMC10149505-41392_2023_1393_MOESM2_ESM.xlsx-CPCMR-Hugo_Symbol_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
K562_SL-327_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0187095
PMC12663032-mmc7.xlsx-Supp_T6-Supplemental_Table_6_Dual_treated_vs_vehicle_treated_MSC_top_DEGs_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Zfx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.1629
NME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23196
K562_Temsirolimus_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141714
PMC12585103-pbio.3003444.s013.xlsx-List_of_genes_for_GO_analysis-List_of_genes_undergoing_significant_MXE_upon_PRMT5_KD_under_hypoxia_AR	Rummagene Transcription Factor Associations 2026	1.0	null
A549_SRT3025 HCl_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0127863
MCF7_Tofacitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139044
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2092
496100385_TCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14265
A549_Bosutinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015783
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1611
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.3091
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0516
MCF7_NVP-BSK805 2HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0132327
K562_Curcumin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153799
MCF7_Ofloxacin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0189976
MCF7_Cyclocytidine HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134333
K562_TMP195_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151123
PMC10154349-41418_2023_1142_MOESM6_ESM.xlsx-Sheet1-Supplementary_data_3_Genes_positively_correlated_with_HOXC13-AS_in_skin_granular_cells_correlation_coefficients_cor_0_FDR_0_05_HOXC13	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Aurora A Inhibitor I_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0203376
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02008
TTI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23201
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6033
CMTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44198
BECN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17672
MCF7_Tazemetostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0219852
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7673
PMC9207509-DataSheet_1.docx-3-FOXK1_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
RPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4681
MCF7_Belinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0113366
K562_BMS-754807_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014108
A549_Mesna_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0121737
K562_Gandotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161387
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4703
K562_ITSA-1_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0343656
K562_Trametinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0112021
PMC10652340-ACEL-22-e13915-s007.xlsx-FOXJ2-SYMBOL_FOXJ2	Rummagene Transcription Factor Associations 2026	1.0	null
A549_AC480_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147453
K562_PD98059_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0206212
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Up_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7647
TAF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3456
RIOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13355
CCDC113	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18932
MYADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57399
PMC9950457-mmc3.xlsx-AP2A_binding_sites_GRHL2_KO-LRRC32_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.575
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.8754
MCF7_Mercaptopurine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126461
A549_Tozasertib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153256
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8683
PMC3419980-leu201249x6.xls-RUNX1-DHS-1000bp-Unnamed_0_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.6532
Colorectal cancer (alcohol consumption interaction)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
NACA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76118
MCF7_Crizotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164121
PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
CTBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23663
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25382
K562_Curcumin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0179388
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1539
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4123
A549_Avagacestat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169981
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5929
K562_Divalproex Sodium_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153536
K562_Zileuton_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0219352
K562_Fluorouracil_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0232409
K562_S3I-201_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170053
MCF7_GSK-LSD1 2HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142774
PMC4383005-ncomms7500-s3.xlsx-Supplementary_Table3-Supplementary_Data_2_HES5_vs_HES5-_expression_intensity_ratios_during_NSC_progression_HES5	Rummagene Transcription Factor Associations 2026	1.0	null
PGPEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01775
DLG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88401
LRRC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26989
PMC8384902-mmc6.xlsx-DEG_3TF_KD_unique-GeneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Downregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PHB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18692
CKS1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36798
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6203
UVSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35187
DCAF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29658
K562_Droxinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156401
NUTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23342
IRF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8322
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Glesatinib(MGCD265)_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148401
MCF7_Tie2 kinase inhibitor_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161531
MCF7_Rigosertib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0116542
A549_S-Ruxolitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131081
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6463
POC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51569
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3735
PMC12079334-ADVS-12-2501734-s002.pdf-101-ENSG00000175787_ZNF169	Rummagene Transcription Factor Associations 2026	1.0	null
SVIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39519
K562_FLLL32_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0196712
PMC8384902-mmc7.xlsx-163_NKX2-1_ChIP_3TF-KD-Unnamed_15_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SERPING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07661
PMC5777794-oncotarget-08-115570-s002.docx-0-HOXA10_HOXA10	Rummagene Transcription Factor Associations 2026	1.0	null
K562_JQ1_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0191615
RPL31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37052
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2932
K562_ENMD-2076_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159583
PMC11976845-pr4c00864_si_003.xlsx-Data_S2E_HeLa_LF-Unnamed_4_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9675
MCF7_Ramelteon_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.01394
TLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41296
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0874
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.393
496100637_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18486
A549_Iniparib_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155207
A549_Flavopiridol HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159564
NUMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08064
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6159
K562_Dasatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0110401
HSD11B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24188
POLR2E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23186
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.119
A549_2-Methoxyestradiol_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150665
A549_AICAR_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0143644
ASRGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21116
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2845
K562_Cimetidine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0211072
K562_Quercetin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142593
A549_Baricitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144351
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1097
MCF7_NVP-BSK805 2HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00989815
THOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49087
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8063
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5413
DYNC2I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03539
K562_Selisistat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0206046
FOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0619
K562_Alvespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0133359
TAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09844
K562_Meprednisone_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0213166
SMARCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88841
MCF7_Clevudine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141521
A549_Capecitabine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178332
MCF7_AZD1480_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161216
CUX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30522
RFX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06205
A549_NVP-BSK805 2HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015396
PMC6879454-Data_Sheet_1.xlsx-AA_in_vitro-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8752721-42003_2021_2991_MOESM4_ESM.xlsx-Fig3_E2F2-gene_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF534	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43876
PMC12956708-DataSheet1.xlsx-Supplementary_Table_7-Supplementary_Table_6_The_DEGs_from_high_altitude_between_AMS_and_non-eAMS_group_of_GSE75665_TWIST2	Rummagene Transcription Factor Associations 2026	1.0	null
BCL11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17384
A549_CYC116_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154245
AKTIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23433
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.3424
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4931
NOMO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08962
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5061
K562_Busulfan_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0218885
MCF7_GSK1070916_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0117644
K562_Anacardic Acid_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176979
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7728
K562_WHI-P154_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0254437
496100602_TCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.19603
PMC3296722-pone.0032481.s009.xlsx-Sheet_1_MSC_vs_references-Gene_Symbol_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
ENTREP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42171
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9544
A549_Quercetin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138422
PMC10335698-pone.0285806.s007.xlsx-DMKN-shRNA_KD_Vs_ShSrc-Unnamed_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SLC4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05539
A549_Momelotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0104806
A549_Cerdulatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00975549
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6549
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Flavopiridol HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157029
S100A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27653
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8002
MCF7_Ramelteon_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0228999
PMC6357748-aau9223_Table_S1.xlsx-CD4_T_-_LPS-Unnamed_0_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Prednisone_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0242761
GRPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0223
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4737
ABHD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49069
PMC8803621-mmc5.xlsx-54JIB-04genes_w_GATA4_motif-GATA4_Q3_GATA4	Rummagene Transcription Factor Associations 2026	1.0	null
ABLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43518
CCDC61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18703
ACTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27186
GON4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10039
CFAP410	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08264
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_EC109_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SH3GLB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42917
RABL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38862
K562_Tacedinaline_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0186278
MCF7_Decitabine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0109172
PMC10624900-41467_2023_42825_MOESM13_ESM.xlsx-Module_19-TFAP2B_TFAP2B	Rummagene Transcription Factor Associations 2026	1.0	null
496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.62003
MCF7_TGX-221_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168487
MCF7_JNJ-7706621_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159825
MCF7_UNC1999_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157783
MCF7_Costunolide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0216049
ZNF880	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38866
SLC16A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81388
K562_AT9283_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132887
K562_SL-327_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.019738
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5902
MCF7_Carmofur_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0192971
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1271
K562_Entinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156098
496100575_PCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.34371
K562_Motesanib Diphosphate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0208685
K562_Ivosidenib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0277616
A549_PCI-34051_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158084
NFATC2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3034
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4527
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.925
C17orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0131
496100626_FWM_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2815
K562_UNC0631_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0216453
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7168
MCF7_SL-327_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157135
K562_Temsirolimus_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136668
PMC4026482-pone.0097702.s010.xlsx-LPS_1_8FC_3hour-Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
A549_BMS-911543_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0182241
MCF7_Alisertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.012797
K562_MLN8054_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0218817
IGDCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13335
PIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01857
MCF7_Valproic acid sodium salt_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145059
K562_XAV-939_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0250154
PMC5140759-NIHMS819001-supplement-supp_dataset3.xlsx-d_GFPoe_vs_CPEB1oe-Table_S3d_APA_events_in_CPEB1_overpressing_HFFs_CPEB1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05587
A549_IOX2_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0198387
ATF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1325
STRADA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02117
A549_PD98059_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0246061
MCF7_Navitoclax_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128068
FNBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20502
MCF7_Mesna_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0230018
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4429
RPSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26808
MAD2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14942
SUOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05428
K562_Pirarubicin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0191424
MCF7_UNC1999_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162613
MCF7_Regorafenib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126784
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.81989
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7826
A549_Droxinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0196705
K562_ENMD-2076 L-Tartaric acid_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0182415
MCF7_Pelitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125377
PMC12824661-BLOOD_BLD-2024-027020-mmc6.xls-Table_S14-HES4_Down_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Azacitidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151813
MCF7_Thiotepa_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144902
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_up-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33586
K562_AC480_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0182449
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TFDP1_TFDP1	Rummagene Transcription Factor Associations 2026	1.0	null
COX7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13998
PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
POU4F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4859
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.554
NR2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21326
PMC9714459-DataSheet3.xlsx-Supplement_3A-1037_elements_included_exclusively_in_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Fasudil_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0190492
K562_BMS-265246_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0223297
PIGW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60708
K562_PCI-34051_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0227814
A549_Mesna_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154778
SPPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10838
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4961
K562_BMS-911543_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0321707
K562_Carmofur_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0198828
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.03764
ENTPD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04252
EFTUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20994
A549_Thiotepa_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153577
K562_Amisulpride_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155434
RAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01257
A549_Altretamine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131867
K562_GSK-LSD1 2HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173729
PMC4909989-ncomms11840-s2.xlsx-up-regulate-The_YAP_TEAD4-FL_YAP_TEAD4-S_and_YAP_RBM4_regulated_genes_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0129
RHEBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97483
K562_Motesanib Diphosphate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0186171
A549_Tucidinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130287
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-DDX5_KD_K562-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Gandotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168186
MCF7_Avagacestat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126461
Zfp335	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.631
MCF7_Cyclocytidine HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.013972
PMC11474056-pnas.2404841121.sd01.xlsx-Supplemental_Table_8_Fig1G-H-Supplemental_Table_8_Transcriptomic_overlap_between_LPS_and_Sepsis_and_or_Tuberculosis_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
A549_PHA-680632_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0187932
FAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3551
A549_FLLL32_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01683
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_14_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Disulfiram_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0201845
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53041
TMEM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4028
PMEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05911
K562_Momelotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0183756
PMC12068594-pgen.1011693.s007.xlsx-MCR_vs_FCG_chr-gene_id_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55587
PMC6935105-40170_2019_206_MOESM9_ESM.xlsx-HIF1_down_VENN-1175_elements_included_exclusively_in_HIF1_down_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
IFRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14033
LSM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22395
FBXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32818
UTP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1599
MCF7_Entacapone_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0201103
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7783
PMC6484770-41388_2018_602_MOESM5_ESM.xlsx-up_P53_vs_con-Unnamed_1_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
K562_Disulfiram_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0218045
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0949
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
ERI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16545
K562_Momelotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146644
SLC52A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.028
K562_Capecitabine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172972
PMC12500496-262_2025_4178_MOESM2_ESM.xlsx-THP1_enriched_for_control-gene_name_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8384902-mmc7.xlsx-163_NKX2-1_ChIP_3TF-KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
K562_PF-3845_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176555
K562_S3I-201_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0300328
A549_MK-5108_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01678
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7721
ATP2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00872
A549_Enzastaurin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164508
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
ADNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2131
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9129
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2362
ZNRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50658
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4113
A549_Belinostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167165
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35796
PMC10760404-NIHMS1688779-supplement-Supplementary_Table_S6.xlsx-EMP_CREB_Targets-symbol_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11839389-PUL2-15-e70058-s003.xlsx-FLF_TBX4_mergeRNAseqChIPseq-symbol_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
CFAP157	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41983
A549_PF-3845_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133752
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0114
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.1501
K562_SRT1720 HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0248595
K562_UNC1999_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0246594
UGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34601
DOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37336
NID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20189