association	dataset	threshold value	standardized value
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01576
hsa-miR-4447	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
visual impairment	HPO Gene-Disease Associations	1.0	null
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.222
PMC3985196-317853.f1.pdf-40-ZNF528_ZNF528	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.927518
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-320d	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
inner ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.545739
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.87155
lysosomal membrane	GO Cellular Component Annotations 2015	1.0	null
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3413
superficial stratum of r3BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02575
hsa-miR-524-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
Perturb_16829_KO_Ras/Apc_SRP306767	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.28764
localization	GO Biological Process Annotations 2015	1.0	null
Prostate disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.939
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38326
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851771
Prostate adenocarcinoma_PRAD_TCGA-EJ-5515-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
optic nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.631205
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20355
SOX3-22085726-MUSCLE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Nr1h3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.2592
Mucopolysaccharidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53043
GTEX-X4XX-0011-R2A-SM-3P623	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22154
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28794
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.838104
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
upper motor neuron dysfunction	HPO Gene-Disease Associations	1.0	null
SLC16A7+ cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.844151
Cortical amygdalar area, posterior part, medial zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.214
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03779
Sarcoma_SARC_TCGA-DX-A3UA-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the anterior segment of the eye	HPO Gene-Disease Associations	1.0	null
shell of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08179
BICR22	CCLE Cell Line Gene CNV Profiles	1.0	2.74314
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
APRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54022
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.939
JHH4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56329
hsa-miR-4291	TargetScan Predicted Conserved microRNA Targets	1.0	0.082179
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7236-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-let-7b	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
TRAPPC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12221
ATP5F1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03247
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972708
VMRCLCP	CCLE Cell Line Gene CNV Profiles	1.0	1.68546
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97269
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3688-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
supraoptic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18481
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nucleus of reunions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32104
ZNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37084
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Globoid cell leukodystrophy disease specific cell type	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.645
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
KYSE-140	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ventral linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05284
interstitial nucleus of the zona limitans	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08179
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3K_Peaks_wtYAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
OCIM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80727
STAT3	ENCODE Transcription Factor Targets	1.0	null
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888368
ae2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.917
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE118816_0_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
PATU8988T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72935
external genital hypoplasia	HPO Gene-Disease Associations	1.0	null
posterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.840612
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03291
THRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71734
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NV-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dentate gyrus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59489
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04422
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00354
GSE188721_2_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6344081-elife-40364-supp8.xlsx-PLZF-Si-diff-expressed-gen-Down-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
negative regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07129
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09657
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF585B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7091
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83515
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17617
PMC6070530-41398_2018_200_MOESM3_ESM.xlsx-regional_cluster_PFC-MSC-age-bin_10_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
C8166	DepMap CRISPR Gene Dependency	1.0	3.65343
PMC8283158-mmc2.xlsx-TCF4_ChIP-symbol_TCF4	Rummagene Transcription Factor Associations 2026	1.0	null
SCLC21H	CCLE Cell Line Gene Expression Profiles	1.0	1.3621
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0774
cystinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.05177
reticular formation of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27698
SUZ12-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.65182
RL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
carboxylic acid transport	GO Biological Process Annotations 2023	1.0	null
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61114
PPARG	ChEA Transcription Factor Targets	1.0	null
LIN28A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11464
l89p	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.213
mantle zone of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61863
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Primary B cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.91907
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41891
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.3037
Hyperprolinemia type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE187006_3_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53296
HLF	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3741
TF1	DepMap CRISPR Gene Dependency	1.0	4.03089
Prostate adenocarcinoma_PRAD_TCGA-G9-6384-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.10211
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.1744
abnormality of higher mental function	HPO Gene-Disease Associations	1.0	null
Mesothelioma	HuGE Navigator Gene-Phenotype Associations	1.0	null
IGFBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66105
REST	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3119	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
ULK2	Kinase Library Serine Threonine Kinome Atlas	1.0	null
PMC10592962-media-4.xlsx-OC2_genes-gene_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
DPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70021
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
icSARS CoV_24Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.31192
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-514b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
Seasonal affective disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.034
abnormal eye morphology	HPO Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05232
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.31065
hsa-miR-4762-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
Lysinuric protein intolerance	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.696
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.843282
hsa-miR-708	TargetScan Predicted Conserved microRNA Targets	1.0	0.085563
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
prostate	HPA Tissue Protein Expression Profiles	1.0	1.56086
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-let-7c	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
abnormal nasal morphology	HPO Gene-Disease Associations	1.0	null
SLC25A19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77363
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37626
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
INSM1_KO_GDS5066_472_mouse_pituitary gland	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29615
Activating signal cointegrator 1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.313
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824625
Perturb_699_KO_INTS6_SRP299234	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.0177
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44892
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
hsa-miR-1	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100281_HIP_probable Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.11261
retinal degeneration	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08436
SNU503	CCLE Cell Line Gene CNV Profiles	1.0	1.58371
HSPA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25418
MTF2	ChEA Transcription Factor Targets	1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.03785
synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.360133
TE6	DepMap CRISPR Gene Dependency	1.0	2.55532
DHFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99564
hsa-miR-873	TargetScan Predicted Conserved microRNA Targets	1.0	0.02226
TM31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56208
GSE205550,GSE205552_2_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
lateral group of nuclei, right, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13094
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25503
SUZ12	ChEA Transcription Factor Targets	1.0	null
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890641
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918644
ALCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.662
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	131.385
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
MFAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01174
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALL-SIL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SOX2_01_350	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.17189
abnormality of the nasal bridge	HPO Gene-Disease Associations	1.0	null
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846085
MT-ND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63706
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831727
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.994561
ventral lateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58082
647V	DepMap CRISPR Gene Dependency	1.0	4.09504
Ost-alpha/Ost-beta complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.091
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE98082_1_v_0_ino80_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of male external genitalia	HPO Gene-Disease Associations	1.0	null
Retinitis pigmentosa 71	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.465
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042369
Autosomal Recessive Retinitis Pigmentosa	DisGeNET Gene-Disease Associations	1.0	null
Carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.939
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.30758
SPI1	ChEA Transcription Factor Targets	1.0	null
Perturb_13844_KD_Hs6st1_SRP371980	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.86769
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.968569
alpha-TC1.6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.011
YY1	ENCODE Transcription Factor Targets	1.0	null
EBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46144
lytic vacuole	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14056
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40217
A-Netherlands-602-2009(H1N1)_7Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.10594
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46234
PMC9232687-13238_2021_887_MOESM3_ESM.xlsx-37_KD_sgCDC20_vs_sgNTC-Differentially_expressed_genes_DEGs_upon_CDC20_knockdown_under_37_culture_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_8658_KO_TP53_SRP251281	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.057008
Perturb_15651_OE_Ccnj_DRP008918	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.12859
body of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34698
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.862
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A4Z3-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Endolysosome lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.738
TMEM258	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91969
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dentate gyrus, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61739
hsa-miR-3652	TargetScan Predicted Conserved microRNA Targets	1.0	0.085563
A-Netherlands-602-2009(H1N1)_48Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.78581
FARAGE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal retinal pigmentation	HPO Gene-Disease Associations	1.0	null
TMEM184A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32508
mitochondrial part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.091767
PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2	Rummagene Transcription Factor Associations 2026	1.0	null
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.913621
Hydranencephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.324
hsa-miR-4747-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS	ChEA Transcription Factor Targets 2022	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MS-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04877
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
496100396_HIP_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1527
GSE171826_1_v_3_rosiglitazone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BICR22	DepMap CRISPR Gene Dependency	1.0	3.09429
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31519
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04313
abnormality of the endocrine system	HPO Gene-Disease Associations	1.0	null
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.3358
H3K27me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KCNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11209
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
LN340	DepMap CRISPR Gene Dependency	1.0	2.85263
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_8601_KO_Pyk2_SRP285527	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.28686
Presynaptic density	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.783
SNU216	DepMap CRISPR Gene Dependency	1.0	2.4913
BRD4-25478319-HGPS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
negative regulation of phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
NCIH2170	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55092
Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the cardiovascular system	HPO Gene-Disease Associations	1.0	null
substantia innominata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.834333
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53053
SPEGNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46805
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.870919
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RMUGS	DepMap CRISPR Gene Dependency	1.0	2.71523
CBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49277
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.226
gamma-aminobutyric acid transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MS-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131887_5_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SUZ12-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE165308_1_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46379
hsa-miR-4712-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01201
Anteverted Nostril	DisGeNET Gene-Phenotype Associations	1.0	null
hsa-miR-548an	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
DYRK1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67181
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00677
CPSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	1.0	null
adrenal_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.03239
amino acid transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RIOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4741
KIF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10438
superficial stratum of the VAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19582
scarring	HPO Gene-Disease Associations	1.0	null
PIP5K1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48486
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01568
Brain Lower Grade Glioma_LGG_TCGA-HT-A74L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98278
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864962
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.70403
CYP26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09472
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.5908
GPRASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60899
cataract	HPO Gene-Disease Associations	1.0	null
LCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57526
dorsal part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.31535
LYSET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16806
NCIH2172	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83566
GSE233679_14_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00619
hsa-miR-330-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28303
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.10209
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4625
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898239
hsa-miR-1285	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41662
Perturb_8662_KO_TP53_SRP251281	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10726
SCH	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CBFA2T2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12118
NR3C1-34362910-WISTARRAT-HIPPOCAMPUS	ChEA Transcription Factor Targets 2022	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0588
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
KPNYN	CCLE Cell Line Gene Expression Profiles	1.0	1.45662
hsa-miR-4446-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36823
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pleural Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
functional abnormality of the inner ear	HPO Gene-Disease Associations	1.0	null
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26768
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827909
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF746	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11911
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05694
REST_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2614
EZH2	ENCODE Transcription Factor Targets	1.0	null
H3K9me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Midline group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49756
REST_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7051-11A-02R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.14507
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.16155
Cochlear hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.109
Nystagmus	DisGeNET Gene-Disease Associations	1.0	null
NH6	CCLE Cell Line Gene Expression Profiles	1.0	1.6503
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RELA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5556
hsa-miR-98	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
central part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65717
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Ophthalmoplegia	DisGeNET Gene-Phenotype Associations	1.0	null
LSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46751
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Congenital nystagmus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
abnormality of the vasculature	HPO Gene-Disease Associations	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.916738
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.0076
abnormality of eye movement	HPO Gene-Disease Associations	1.0	null
PPP1CA	Pathway Commons Protein-Protein Interactions	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14066
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8245
Photophobia	DisGeNET Gene-Phenotype Associations	1.0	null
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.38632
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PU-01A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE129241_1_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4895
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932995
hsa-miR-1224-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
ZNF407	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92159
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	2.05249
PMC4619688-pone.0140684.s004.xlsx-Sheet6-AA_change_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SIAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56138
ANKRD33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79335
organelle inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.160053
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.9521
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64416
PMC12216174-41598_2025_6356_MOESM13_ESM.xlsx-Sheet1-Supplementary_Table_3_Classification_of_amino_acid_AA_transporters_at_four_different_subcellular_localizations_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.993966
PMC9578714-elife-81083-supp2.xlsx-AA_Transporters-Ensembl_ID_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07022
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
RAPGEFL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52986
nucleus of the central acoustic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07821
Perturb_8834_KO_MESP1_SRP345831	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11484
Retinitis pigmentosa	ClinVar Gene-Phenotype Associations 2025	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0723
Rif1_KD_GDS4943_242_mouse_J1 embryonic stem cell (ESCs) line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
amino acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
REST_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLHL42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65613
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2414
benign mesothelioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.633169
visual	GeneRIF Biological Term Annotations	1.0	null
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_up-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-501-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
PR cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.938
cancer	GWASdb SNP-Disease Associations	1.0	0.047456
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r2 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29074
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09175
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
MISP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2565
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.309
496100572_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1779
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
precommissural nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40464
CD200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05986
hsa-miR-3692	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
hsa-miR-3682-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.873491
GSE207787_1_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NSMCE4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34202
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypoplastic male external genitalia	HPO Gene-Disease Associations	1.0	null
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EPLC-272H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.2509
EAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37089
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19748
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.915192
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17577
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4239
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
Central medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04469
Eye degenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.016
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.89288
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29048
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
E4F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16967
abnormality of the nose	HPO Gene-Disease Associations	1.0	null
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83515
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55403
nucleus of the diagonal band, left, vertical division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04516
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03889
SAOS-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-136	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18928
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142684_4_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-450b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044508
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
negative regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
SCMCRM2	DepMap CRISPR Gene Dependency	1.0	2.38082
SERP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12722
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A7HU-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
juvenile	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260945
HMGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13903
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.859298
hsa-miR-4751	TargetScan Predicted Conserved microRNA Targets	1.0	0.17031
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38931
NCI-H1304	COSMIC Cell Line Gene CNV Profiles	1.0	2.26395
HENMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45102
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4662b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6536
intermediate stratum of p2ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08048
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29266
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831502
FBXO33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63134
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HI-7168-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863567
Retinitis Pigmentosa	DisGeNET Gene-Disease Associations	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4607
TMUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05193
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5983
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Nystagmus	DisGeNET Gene-Phenotype Associations	1.0	null
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03811
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
LI7	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57897
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S7C-GENE_LIST_UPLOADED_TO_ENRICHR_MAX_KO_TESTES_627_GENES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
HNF4A	ChEA Transcription Factor Targets	1.0	null
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.84034
Inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.398
spleen	GTEx Tissue Gene Expression Profiles	-1.0	-1.17966
SOX2_01_96	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.61627
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870186
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spinocerebellar ataxia type 34	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
VCX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69699
regulation of dephosphorylation	GO Biological Process Annotations 2015	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A56S-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-520h	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941015
SQSTM1_OE_GDS2653_651_human_IMR-32 neuroblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.854743
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8168-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97505
GSE112860_5_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18269
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Ensembl_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.09513
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22012
RBM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36586
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38384
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
inner SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.907948
SRC_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-539	TargetScan Predicted Conserved microRNA Targets	1.0	0.078844
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.029231
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95511
disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GPR150	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74496
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APH1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89442
SHH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51568
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MT-ND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93334
Synaptic ribbon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.616
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33019
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25252
GSE77108_0_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTV1DM	DepMap CRISPR Gene Dependency	1.0	4.21405
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.95081
Pseudoretinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.341
GLC82	CCLE Cell Line Gene CNV Profiles	1.0	1.3558
PMC8528285-pbio.3001085.s010.xlsx-Fig_7G-MAX_KO_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
PK8	DepMap CRISPR Gene Dependency	1.0	5.74342
YBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35392
superior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.889033
ZNF616	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13126
RAD21	ENCODE Transcription Factor Targets	1.0	null
Dicarboxylic aminoaciduria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.745
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.54862
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10087
BLOC-3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.542
HES7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51707
negative regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
Hyperargininemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
TMEM169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88272
Utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.971
BFTC-905	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09345
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.958266
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00111
hsa-miR-4276	TargetScan Predicted Conserved microRNA Targets	1.0	0.107229
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_5387_KO_Isl1_SRP380182	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.483
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35044
Optic nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.309
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4288
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-544	TargetScan Predicted Conserved microRNA Targets	1.0	0.111118
H3K27me3_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.21271
NT5C3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58662
BCP1	CCLE Cell Line Gene Expression Profiles	1.0	1.3532
pleural cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.795821
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31966
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bestrophinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4472	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Perturb_6012_KD_ERH_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.0494
Endocardium disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
H3K9ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5402-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3504
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24599
REST_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_14_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3617	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043425
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00968
mode of inheritance	HPO Gene-Disease Associations	1.0	null
PMC9810646-41598_2022_27273_MOESM1_ESM.docx-1-ZNF786_ZNF786	Rummagene Transcription Factor Associations 2026	1.0	null
Interanteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.17914
cone-rod dystrophy 16	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869606
XPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71043
carboxylic acid transport	GO Biological Process Annotations 2015	1.0	null
NKM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24102
retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.078492
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.963129
Perturb_9086_KO_YAP_SRP297717	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC11061611-cd-23-0857_table_s4_suppst4.xlsx-Epithelial_F1-pEpi11_FU1_shared_B_ASCL1_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.181607
sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.280796
Prostate adenocarcinoma_PRAD_TCGA-G9-6367-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	1.0	3.71984
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.85187
MYBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66584
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.49652
liminal part of the r6 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61863
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21094
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.39919
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.853714
ChIP_K27me3_17603471_mouseNPC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.53965
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.887867
NCIH3255	CCLE Cell Line Gene CNV Profiles	1.0	1.41721
hsa-miR-448	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
Perturb_13802_KO_Mettl14_SRP286301	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
MEIS1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
Hartnup disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11378
hsa-miR-641	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
Perturb_15647_KD_Hnrnpm_SRP222089	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.78401
AGER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06984
DOT1L_DELETION_GDS4295_428_mouse_AF9 - Mixed Lineage Leukemia (MLL) cells -  7 days	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Refractive error	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.375
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
Cone dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
SDHAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76864
hsa-miR-3121-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.062888
GSE183335,GSE183351_1_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81I-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM1799	DepMap CRISPR Gene Dependency	1.0	3.56204
amino acid metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.372958
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CKAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23705
KLK13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00713
orbital frontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.848588
GSE210101,GSE210114_5_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
negative regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
GSE233679_12_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15565
hsa-miR-3124-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.140752
PCSK1N	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00756
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASH-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Retinitis pigmentosa 66	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.404
Perturb_16520_KD_Pou2f3_SRP343255	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.31957
GSE210101,GSE210114_6_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NOP56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01203
posteroventral (inferior) parietal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.838743
FUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75883
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.842246
SNU1033	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64733
PMC7397849-supp_gad.338681.120_Supplemental_Table_S1.xlsx-S1L_Shared_genes_3way_overlap-Suppl_Table_S1L_Shared_genes_between_YAP1-MAMLD1_YAP1-FAM118B_YAP1-TFE3_in_vitro_human_samples_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.997373
SNU1214	CCLE Cell Line Gene CNV Profiles	1.0	1.46319
PMC12178937-mmc6.xlsx-D_MAFF_KDvsD_C_deg_all-gene_id_MAFF	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17661
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.847148
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960428
Paraventricular nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59197
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.54197
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.0784
RET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52412
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916766
hsa-miR-4701-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Eye disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12768
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cellular metabolism and vesicular transport regulation	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
PMC7862469-13238_2020_779_MOESM4_ESM.xlsx-FOXO3-GE_VS_WT-Symbol_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
RH30	CCLE Cell Line Gene Expression Profiles	-1.0	-2.67154
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.73983
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8503
H3K9me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
KYSE270	CCLE Cell Line Gene CNV Profiles	1.0	1.90168
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE77795_0_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
triangular septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8313
Developmental and epileptic encephalopathy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.581
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CSR_EARLY_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40652
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1671
Prostate adenocarcinoma_PRAD_TCGA-EJ-7317-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.94543
Perturb_4722_KO_Smarcc1/Smarcc2_SRP124677	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.85412
abnormality of the male genitalia	HPO Gene-Disease Associations	1.0	null
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08576
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31839
JUN-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25719
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0438
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Retinal dystrophy	ClinVar Gene-Phenotype Associations 2025	1.0	null
conductive hearing impairment	HPO Gene-Disease Associations	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74513
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXB7-26014856-BT474-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdalohippocampal transition zone, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19179
MXI1	ENCODE Transcription Factor Targets	1.0	null
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04602
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.890663
MYC	ENCODE Transcription Factor Targets	1.0	null
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-485-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18399
SYNGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31468
ZNFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19589
abnormal genital system morphology	HPO Gene-Disease Associations	1.0	null
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-668	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34157
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-S_48h_2-down-regulated_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.34735
thin retina outer nuclear layer	MGI Mouse Phenotype Associations 2023	1.0	null
Choroid disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.243
abnormality of the middle ear	HPO Gene-Disease Associations	1.0	null
Perturb_14267_OE_Mir144_SRP305305	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Brush border membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.866
RCOR1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.690451
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
Physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26751
Oculocutaneous albinism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.005
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18232
intracellular part	GO Cellular Component Annotations 2015	1.0	null
ONS76	CCLE Cell Line Gene CNV Profiles	-1.0	-2.65154
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.832035
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0528
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
CCDC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17952
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.3085
TALL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4434
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83515
regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
anion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
HCC95	CCLE Cell Line Gene CNV Profiles	1.0	1.72475
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6268
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	129.182
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_48h_1-Unnamed_0_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
Hereditary spastic paraplegia 42	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.478
EMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53585
hsa-miR-665	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19685
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12436
OPTN_KD_GDS2892_268_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Glaucoma	DisGeNET Gene-Disease Associations	1.0	null
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42075
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	1.24054
N4BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58072
Perturb_700_KO_INTS6_SRP299234	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-18.9586
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE115542_2_v_4_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
EDEM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54028
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.980097
KYSE-270	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_SUZ12_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
IGROV1	DepMap CRISPR Gene Dependency	1.0	2.21176
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1229
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.98296
ESR1-22446102-UTERI-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
amino acid transmembrane transport	GO Biological Process Annotations 2015	1.0	null
PMC7401461-iovs-61-3-10_s001.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0101
abnormality of the integument	HPO Gene-Disease Associations	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3161	TargetScan Predicted Conserved microRNA Targets	1.0	0.165047
Obesity (extreme)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.6
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05382
Brain Lower Grade Glioma_LGG_TCGA-HT-8109-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1734	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.93185
Perturb_16522_KD_ASXL3_SRP247927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SLC16A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24641
GSE211177,GSE211178_8_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_14_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46775
abnormality of the inner ear	HPO Gene-Disease Associations	1.0	null
RBL1_KO_GDS1932_739_mouse_Neurospheres	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
mitochondrial membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.187333
GSE233679_12_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
chr3_170573143_C_T_b38	GTEx eQTL 2025	1.0	1.69202
Supportive connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.553
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.833549
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27304
496100555_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.77587
LDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32334
ZNF444	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26917
EZH2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ornithine translocase deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90168
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7391
abnormality of the nasal alae	HPO Gene-Disease Associations	1.0	null
Prostate carcinoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.939
GATA3_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34607
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLF17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.5736
GAL3ST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.20009
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PDCD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14861
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.81626
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825286
H3K27me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-548ac	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
hsa-miR-466	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
NCIH1385	CCLE Cell Line Gene Expression Profiles	1.0	1.54121
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE201239_3_v_4_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35236
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Abnormality Of Retinal Pigmentation	DisGeNET Gene-Phenotype Associations	1.0	null
abnormality of the lens	HPO Gene-Disease Associations	1.0	null
NPHP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.855
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837725
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKHEP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55933
SUZ12-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
GSE222574_0_v_2_lmna_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the head	HPO Gene-Disease Associations	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NH-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
Lysosomal membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12759
hsa-miR-4282	TargetScan Predicted Conserved microRNA Targets	1.0	0.078844
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-cARID1A_KD_genes_down-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Olivocerebellar fiber system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.947
dorsal lateral geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21857
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042088
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4448	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.960812
transport	GO Biological Process Annotations 2015	1.0	null
PMC10290283-biol-2022-0622-sm3.pdf-92-ZNF625_ZNF625	Rummagene Transcription Factor Associations 2026	1.0	null
WWP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13426
REST_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
olivary pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79671
DB	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98985
hsa-miR-4647	TargetScan Predicted Conserved microRNA Targets	1.0	0.003282
RFX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4147
Carcinoma, Squamous Cell	CTD Gene-Disease Associations	1.0	1.33081
GSE232564,GSE232566_0_v_2_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13059_Mut|OE_Sik3E13_SRP334442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.66319
disease	GWASdb SNP-Disease Associations	1.0	0.025594
abnormality of the pleura	GWASdb SNP-Phenotype Associations	1.0	0.949798
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS20	DepMap CRISPR Gene Dependency	1.0	4.11804
Retinitis pigmentosa 88	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.4
Prostate adenocarcinoma_PRAD_TCGA-EJ-7331-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835083
lateral part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10736
periventricular stratum of RtC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45823
PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Supplemental_Table_6_Genes_downregulated_in_NEUROG3-_-_hESC_line_differentiated_to_pancreatic_endocrine_progenitors_d13_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.982495
negative regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
ZNF610	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	92.2355
diethylstilbestrol_rattus norvegicus_gpl1355_brown norway_gds2913	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NEURL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86636
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.956984
Mueller cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.947
LBH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77006
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972672
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
night blindness	HPO Gene-Disease Associations	1.0	null
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0775
vacuolar part	GO Cellular Component Annotations 2015	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.924381
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0106
hsa-miR-3121-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE183335,GSE183351_3_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186633_1_v_0_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10736
SLC25A33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27917
MRPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6685
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	2.23401
Outer nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.365
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044278
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FTC-133	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anteromedial nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59107
ophthalmoparesis	HPO Gene-Disease Associations	1.0	null
PMC7893891-12860_2021_343_MOESM1_ESM.xlsx-Fig3C_D13vsD7-FOXP2_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
CTBP1-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100462_PCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.12748
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.1477
hsa-let-7f	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
BICRAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9609
lat1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.838
Precursor Cell Lymphoblastic Leukemia-Lymphoma	CTD Gene-Disease Associations	1.0	1.04126
eye and adnexa disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.299092
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945435
496100491_HIP_no dementia_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08715
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.226
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226249_0_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC-27129775-CHIP-SEQ-CORNEA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.14749
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201401_2_v_0_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHP126	CCLE Cell Line Gene Expression Profiles	1.0	1.42771
eye disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
sensorineural hearing loss	MGI Mouse Phenotype Associations 2023	1.0	null
LU99	DepMap CRISPR Gene Dependency	1.0	3.2311
ChIP_SUZ12_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0723
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8416
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06256
Hereditary night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054193
PDCD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71534
Extratemporal epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
PGRMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66371
HCC364	CCLE Cell Line Gene Expression Profiles	-1.0	-1.45973
RMDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12777
ELOVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86427
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55403
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0723
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.918395
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14912_OE_RARRES1_SRP265304	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSMB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62805
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833364
erg_19359602_huvec_lof_human_gpl570_gds3557	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.465311
HUG1N	CCLE Cell Line Gene CNV Profiles	1.0	2.76234
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906736
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
HELLS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19923
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11661
lateral medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09012
hsa-miR-3652	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.630314
negative regulation of phosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-938	TargetScan Predicted Conserved microRNA Targets	1.0	0.131849
Pancreas-pancreatic delta cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.045789
BLOC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.83
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.7724
DCAF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75728
Retinal macular dystrophy 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pontocerebellar fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.004
MYG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13199
HOXC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01625
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
inner hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.18113
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18383
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.57012
abnormality of the ear	HPO Gene-Disease Associations	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the testis	HPO Gene-Disease Associations	1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37129
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CLDN18_KO_GSE48443_44_mouse_lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KE37	DepMap CRISPR Gene Dependency	1.0	2.64644
abnormality of the optic disc	HPO Gene-Disease Associations	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.06406
organic acid transmembrane transport	GO Biological Process Annotations 2015	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
subiculum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12968
vestibular nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.900467
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC12178937-mmc6.xlsx-L_MAFF_KDvsL_C_deg_all-gene_name_MAFF	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1266
abnormality of the external nose	HPO Gene-Disease Associations	1.0	null
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63991
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.830875
primary auditory cortex (core)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.932951
caudal presubiculum (postsubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06393
ERBB3_drugactivation_31_GDS4361	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.28261
NCIH650	DepMap CRISPR Gene Dependency	1.0	3.76397
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.46903
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
REST_Panc1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27436
superficial stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.24462
orphan	GeneRIF Biological Term Annotations	1.0	null
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.835152
EGFR_druginhibition_83_GSE27640	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.53118
GSE234289_4_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.565
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0919
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.839764
GSE162590_1_v_0_gsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE219195_0_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54924
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
REST_Panc1_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer V of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.916647
TRIM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26031
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
NB6	DepMap CRISPR Gene Dependency	1.0	2.15785
cell type cancer	GWASdb SNP-Disease Associations	1.0	0.335055
cone-rod dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.164
GSE203267_0_v_1_alkbh5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3150a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
GSE183335,GSE183351_1_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
increased or absent threshold for auditory brainstem response	MGI Mouse Phenotype Associations 2023	1.0	null
NCI-SNU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050925
hsa-miR-4718	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00157
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102505_6_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.71746
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210101,GSE210114_5_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ECC12	CCLE Cell Line Gene Expression Profiles	1.0	1.79973
PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_20_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6134-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
photoreceptor	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.592043
OVKATE	CCLE Cell Line Gene CNV Profiles	1.0	1.57731
ZFP92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31804
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05978
De Quervain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
LYPLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45593
GSE142232,GSE142234_0_v_2_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VEZT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62451
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_10_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_14102_KD_PML_SRP221023	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
TNRC6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18026
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62833
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35859
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal electroretinogram	HPO Gene-Disease Associations	1.0	null
mitochondrial inner membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.168101
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_16519_KD_C11orf53_SRP343255	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.39395
abnormality of corneal thickness	HPO Gene-Disease Associations	1.0	null
CORL279	CCLE Cell Line Gene Expression Profiles	1.0	2.25279
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992824
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.066292
single-organism localization	GO Biological Process Annotations 2015	1.0	null
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21681
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29543
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RXYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34167
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828508
organic substance transport	GO Biological Process Annotations 2015	1.0	null
496100500_PCx_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.34135
MED25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28584
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.835172
CEBPB-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32351
TE-441-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of the globe	HPO Gene-Disease Associations	1.0	null
Eye degenerative disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
zona incerta	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.84037
backbone	GeneRIF Biological Term Annotations	1.0	null
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
661W cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.268
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0723
abnormality of carbohydrate metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VW-A7QS-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of body weight	HPO Gene-Disease Associations	1.0	null
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14682
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42069
PMC12358249-supplementary_table_s5_ioaf064.xlsx-DMRT1_-_vs_WT__4_months-Unnamed_1_DMRT1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62833
SPHK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77247
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40255
CHD1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4733-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
NES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73932
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.834
HOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05563
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.302478
abnormality of the uvea	HPO Gene-Disease Associations	1.0	null
CHMP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91948
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rostral group of intralaminar nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00369
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TRAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48859
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25557
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95017
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.9506
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-876-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_48h_2-down-regulated_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
IL27RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54101
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEIS2_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1549
abnormality of the genital system	HPO Gene-Disease Associations	1.0	null
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.895682
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.844381
PPP1CC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38576
GEMIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39032
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.7286
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-548n	TargetScan Predicted Conserved microRNA Targets	1.0	0.123298
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219928
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-96	TargetScan Predicted Conserved microRNA Targets	1.0	0.017945
CADOES1	CCLE Cell Line Gene Expression Profiles	1.0	2.12458
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.82943
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855183
JHH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78477
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE171826_1_v_0_rosiglitazone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ventral medial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11579
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26339
GPR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26958
UPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09703
cone-rod dystrophy 12	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.409
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
A2058	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72786
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
medial group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56389
Rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.36918
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
paraventricular nucleus, peduncular or principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0446
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06577
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1152
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MM1S	DepMap CRISPR Gene Dependency	1.0	2.4562
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.16749
diabetes mellitus	HPO Gene-Disease Associations	1.0	null
retinal atrophy	HPO Gene-Disease Associations	1.0	null
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12561
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998677
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.94543
transstimulated	GeneRIF Biological Term Annotations	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0723
enzalutamide_homo sapiens_gpl570_gse44905	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Digitum minimus pedis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.061
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906736
CYFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22338
ATF2	ENCODE Transcription Factor Targets	1.0	null
GSE133763_0_v_1_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF549	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.4036
superficial stratum of DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61739
abnormal involuntary eye movements	HPO Gene-Disease Associations	1.0	null
REST_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CNIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84778
mitochondrial membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.144777
all	HPO Gene-Disease Associations	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.967495
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3767
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28597
vitamin c_mus musculus_gpl6246_gse19378	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-4647	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
hsa-miR-4500	TargetScan Predicted Conserved microRNA Targets	1.0	0.065994
Perturb_17338_KO_Mageb4_SRP259999	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.5448
superficial stratum of r5Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01722
Bladder Urothelial Carcinoma_BLCA_TCGA-2F-A9KW-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP-independent citrate lyase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.118
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.1009
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
granule cell layer of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61239
amino acid transport	GO Biological Process Annotations 2015	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7920-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A116-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.872838
GSE140997_4_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.029201
496100559_FWM_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.3974
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IREB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10373
chr3_170474455_C_A_b38	GTEx eQTL 2025	1.0	1.77059
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2331
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32713
hsa-miR-4659b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
NHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.3189
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.848419
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3136-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A465-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IPC298	CCLE Cell Line Gene CNV Profiles	-1.0	-2.17394
Perturb_9377_KO_lincRNAEPS_SRP354151	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.51308
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18257
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PCF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46027
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47948
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04847
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041745
PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Amplified_upregulated_genes_B_identified_as_synthetic_lethal_with_gene_A_deletion_downregulation_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
Mediodorsal nucleus of the thalamus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3821
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV4-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.508
SUM159PT	DepMap CRISPR Gene Dependency	1.0	3.07497
spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.712959
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49627
BLOC-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.502
negative regulation of phosphatase activity	GO Biological Process Annotations 2015	1.0	null
Retinal rod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.284
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1184	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
EZH2-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SW1271	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CORL24	CCLE Cell Line Gene Expression Profiles	1.0	2.64964
H3K27me3_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAPN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25308
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-1271	TargetScan Predicted Conserved microRNA Targets	1.0	0.015875
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPMI8226	DepMap CRISPR Gene Dependency	1.0	2.0506
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.51061
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05166
MSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11186
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53493
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22473
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04683
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
primary auditory cortex (core)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.948484
phospholipid-translocating ATPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.034
CLDN18_KO_GDS4961_28_mouse_whole lung tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ALYREF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23172
Perturb_1076_KO_Mr1_ERP107271	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.51477
H3K27me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
HNRNPUL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52129
GSE216147_0_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neuro2a	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
superficial stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18214
hearing impairment	HPO Gene-Disease Associations	1.0	null
Stickler syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
GSE245407,GSE245412_0_v_1_smurf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Synaptic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.59
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08048
PPHLN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75154
Spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.264
OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC4686761-ncomms10068-s3.xlsx-S2G-MSC_down_specific-Supplementary_Data_2G_-_expression_of_down-regulated_genes_2_fold_change_specifically_in_MSC_PTEN-_-_vs_MSC_PTEN_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ7-0011-R9a-SM-2TC5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37946
GSE77108_4_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cluster of actin-based cell projections	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.354
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.5935
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047763
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05664
KLK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77323
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38403
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226249_0_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
18318837-TableS2	GeneSigDB Published Gene Signatures	1.0	null
Sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
REST_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.605694
Hyperreflexia	DisGeNET Gene-Phenotype Associations	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6332
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050665
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74767
GATA1-19941827-MEL86-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
r7 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47867
TRIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18466
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01311
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50579
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1132
TP53RK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03689
gata4_16914500_e9dot5_atrioventricular_canal_lof_mouse_gpl1261_gds3663	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.726873
hsa-miR-1289	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
H3K9me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10153
GSE200673,GSE200691_1_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lysosomal membrane	GO Cellular Component Annotations 2025	1.0	null
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.92763
Vestibular hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.306
superficial stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18297
GSE159728,GSE159730_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162087_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NRTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07128
nitrogen compound transport	GO Biological Process Annotations 2015	1.0	null
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.764
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10402
hsa-miR-4755-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.893108
OVK18	CCLE Cell Line Gene Expression Profiles	1.0	1.60775
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916935
layer 1 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08827
basomedial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12407
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12436
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831763
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 part of the trigeminal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18297
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.37142
Lytic vacuole membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
TSG101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74408
REST_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of nervous system physiology	HPO Gene-Disease Associations	1.0	null
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22121
VZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.942335
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.8439
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24248
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991689
GSE210377_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05979
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0327
NB17	DepMap CRISPR Gene Dependency	1.0	3.80418
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07312
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09899
PTTG1IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45339
Hypogonadism	DisGeNET Gene-Disease Associations	1.0	null
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51471
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1966
RAB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52072
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216273,GSE216292_0_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
carrying	GeneRIF Biological Term Annotations	1.0	null
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.915695
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cortical amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26603
APLP2_KO_GDS4414_536_mouse_adult cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
EKVX	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41759
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEx Brain 20-29 vs 40-49	GTEx Tissue-Specific Aging Signatures	-1.0	-6.41377
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34069
8MGBA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5313
abnormality of the face	HPO Gene-Disease Associations	1.0	null
CD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44893
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.940706
EJM	DepMap CRISPR Gene Dependency	1.0	2.58289
DMAC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3978
RPE1SS119	DepMap CRISPR Gene Dependency	1.0	3.2644
KNTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27656
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01468
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3944
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.878909
hsa-miR-505	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
TAF7	ENCODE Transcription Factor Targets	1.0	null
abnormality of the choroid	HPO Gene-Disease Associations	1.0	null
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69211
SMC3	ENCODE Transcription Factor Targets	1.0	null
TMEM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38731
RALBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24789
ERG_01_17	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60329
PMC6347712-pnas.1812449116.sd06.xlsx-iPSC_IRF7_48h_rest_RNAExpress-Gene_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.76053
REST_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02249
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.593247
hsa-miR-3140-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
PcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01526
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909827
GSE120595_5_v_4_arid2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CORL95	CCLE Cell Line Gene Expression Profiles	1.0	1.48539
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050792
hsa-miR-4496	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_downregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.82195
hsa-miR-499a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE118816_2_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
DAUDI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TEAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79237
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.617
mantle zone of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19839
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35004
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8012850__F6	PFOCR Pathway Figure Associations 2024	1.0	null
hsa-miR-3925-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861017
LN464	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61667
SKNFI	CCLE Cell Line Gene Expression Profiles	1.0	2.41055
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49616
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.915192
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.939
hsa-let-7g	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
IFT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2951
PMC7335061-41467_2020_17150_MOESM4_ESM.xlsx-Table_S3-LIN28B_correlates_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE140997_4_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
lateral terminal nucleus of the accessory optic tract, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14353
RCC10RGB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE102467_3_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H727	COSMIC Cell Line Gene Mutation Profiles	1.0	null
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.49366
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2015
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FBXO11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.147
TEAD4_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
REST_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04232
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11213
Cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.265
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49637
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869741
periventricular stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60714
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906687
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.903159
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.9379
wide nasal bridge	HPO Gene-Disease Associations	1.0	null
retinitis pigmentosa 68	OMIM Gene-Disease Associations	1.0	null
Medial geniculate complex, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13005
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SM-01A-12R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867723
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00496
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP5MC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0813
VPS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09059
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.920495
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5441
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827373
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETV4_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Microphthalmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.305
Brain Lower Grade Glioma_LGG_TCGA-DU-A76R-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.92946
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07961
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.20253
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26339
Perturb_4867_KO_HES1/NEUROG3_ERP110708	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.7917
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10166
skin fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.536625
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17537
increased body weight	HPO Gene-Disease Associations	1.0	null
superficial stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28981
PTGR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57612
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE132759_4_v_5_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3123	TargetScan Predicted Conserved microRNA Targets	1.0	0.047969
behavioral abnormality	HPO Gene-Disease Associations	1.0	null
UPCISCC152	DepMap CRISPR Gene Dependency	1.0	7.11046
CRLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8717
HELA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.83515
GSE234289_5_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.911974
musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.161716
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
supraoptic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.39039
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01038
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73733
primary auditory cortex (core)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19023
hsa-miR-3591-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
dorsolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.969889
HCC202	DepMap CRISPR Gene Dependency	1.0	2.99023
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU840	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77796
short photoreceptor outer segment	MGI Mouse Phenotype Associations 2023	1.0	null
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.20138
KNS42	DepMap CRISPR Gene Dependency	1.0	3.9102
disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal glucose homeostasis	HPO Gene-Disease Associations	1.0	null
PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-28-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
Photoreceptor disc membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.213
abnormality of the skin	HPO Gene-Disease Associations	1.0	null
mitochondrial outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.362422
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-283	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30652
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26596
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00831
WM793B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE206093,GSE206094_1_v_3_isl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
ASNSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66937
GSE77108_6_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-DX-A23U-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.12316
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45635
FOXP2	ChEA Transcription Factor Targets	1.0	null
PMC9232687-13238_2021_887_MOESM3_ESM.xlsx-37_KD_sgCDC20_vs_sgNTC-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16076
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18257
r3 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02659
PMC10510228-13287_2023_3481_MOESM7_ESM.xlsx-DEGs-Differentially_expressed_genes_DEGs_in_bone_marrow-derived_MSCs_from_six_human_donors_cultured_at_high_confluency_MSC-HC_versus_low_confluency_MSC-LC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
KNS-62	COSMIC Cell Line Gene CNV Profiles	1.0	2.26395
HIRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09249
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Neuromast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.91
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
neoplasia of the pleura	GWASdb SNP-Phenotype Associations	1.0	0.949798
GSE102505_6_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-let-7i	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.854005
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28732
GSE94849_1_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NKX6-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02165
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01693
Retinal degeneration	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
generalized abnormality of skin	HPO Gene-Disease Associations	1.0	null
INSM1_lack of the seven N-terminal amino acids_GDS5066_404_mouse_pituitary glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
anion transport	GO Biological Process Annotations 2015	1.0	null
cognitive impairment	HPO Gene-Disease Associations	1.0	null
Lateral habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12252
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the nares	HPO Gene-Disease Associations	1.0	null
GSE210101,GSE210114_2_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Retinitis pigmentosa 84	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.455
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39831
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.834303
LMO2-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
putamen, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02068
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
retinal disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
Influenza_B Cell Lymphocyte_GSE3203	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.79204
nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
PMC4051124-1471-2164-15-256-S16.XLSX-WES_IPD-RBCK1_2-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40874
hilus of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45374
hsa-miR-4661-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.004732
intermediate stratum of DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45586
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GDF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6957
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Intraciliary transport particle B	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.786
SMG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3805
Aland Island eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
ZNF681	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18834
PMC4387713-supp_gad.255984.114_Table_S4.xlsx-S4A-Down_Nanog_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-6867-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16508_OE_Rest_SRP314492	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Thymic carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.78
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890739
LAMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.45523
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.906736
Retinal pigment epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.478
GSE228992_0_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
carboxylic acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.37908
hsa-miR-4659a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830397
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pou5f1_20526341_human_embryonic_stem_cells_hesc_lof_human_gpl6947_gse21135	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.157289
CTPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03452
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04025
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98979
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06779
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47638
TO14	DepMap CRISPR Gene Dependency	1.0	2.98206
GSE178907_4_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21678
cellular_component	GO Cellular Component Annotations 2015	1.0	null
SKBR3	DepMap CRISPR Gene Dependency	1.0	2.68775
AR	ChEA Transcription Factor Targets	1.0	null
inner SZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.880606
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Nyctalopia	DisGeNET Gene-Disease Associations	1.0	null
GLIS3_KO_GDS3812_500_mouse_Embryonic pancreas at E15.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
basal nucleus of Meynert	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35487
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	121.438
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860975
SNRNP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41306
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34945
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876761
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21862
GSE211177,GSE211178_9_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.226
atypical scarring of skin	HPO Gene-Disease Associations	1.0	null
hsa-miR-634	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29015
lysosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3920	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.1607
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bietti crystalline corneoretinal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
mantle zone of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.3177
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.909706
EBF1-22473956-LYMPHODE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.875173
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4727-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-RA-A741-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
253J	DepMap CRISPR Gene Dependency	1.0	2.50463
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.08803
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15384
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.901419
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.939
Peripheral retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
transporter activity	GO Molecular Function Annotations 2015	1.0	null
Obesity	DisGeNET Gene-Disease Associations	1.0	null
A375	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32445
MAK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57451
optic atrophy	HPO Gene-Disease Associations	1.0	null
ZNF784	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2668
hsa-miR-513c	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.270214
GSE230656_0_v_1_gsdmd_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Infertility, Male	CTD Gene-Disease Associations	1.0	1.22306
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.02848
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	36.8632
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_72h_2-down-regulated_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
organic anion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0979
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09723
M040416	DepMap CRISPR Gene Dependency	1.0	2.04828
Glycolate oxidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.631
Uterine Carcinosarcoma_UCS_TCGA-NA-A5I1-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-320c	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
paraventricular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20664
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164874_5_v_11_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825692
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70085
PANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25499
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063885
PMC11799530-12276_2024_1380_MOESM1_ESM.xlsx-DEG_KD_PC-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chimera	GeneRIF Biological Term Annotations	1.0	null
magnocellular (medial) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01227
abnormality of the retina	HPO Gene-Disease Associations	1.0	null
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.939
organic acid transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-206	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	2.17942
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PMC12448905-vlaf042_supplementary_data.pdf-82-NPAS2_NPAS2	Rummagene Transcription Factor Associations 2026	1.0	null
Cell type cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.939
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071776
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.875242
abnormality of the vasculature of the eye	HPO Gene-Disease Associations	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-384	TargetScan Predicted Conserved microRNA Targets	1.0	0.042355
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.832934
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866452
hsa-miR-365	TargetScan Predicted Conserved microRNA Targets	1.0	0.131849
hsa-miR-4747-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
P53-22387025-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07487
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.857047
SPI1-23127762-K562-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09038
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25431
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19189
MRPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73279
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.2746
Paraventricular hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00056
hsa-miR-3978	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
Glucosidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.142
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4007
SLR23	DepMap CRISPR Gene Dependency	1.0	2.74782
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Developmental delay and seizures with or without movement abnormalities	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.401
RUNX1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZSCAN5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02261
H2BC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00478
HDQP1	CCLE Cell Line Gene CNV Profiles	1.0	1.36227
Fatty Liver	CTD Gene-Disease Associations	1.0	1.25276
LRRC41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16507
Retinitis pigmentosa 68	ClinVar Gene-Phenotype Associations	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TGFBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3905
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
functional abnormality of the middle ear	HPO Gene-Disease Associations	1.0	null
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1734	COSMIC Cell Line Gene CNV Profiles	1.0	2.26395
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95555
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-656	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.956321
GSE233679_6_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.76227
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82341
ERI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.56965
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.414
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10546
Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Progressive Night Blindness	DisGeNET Gene-Phenotype Associations	1.0	null
ventromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76417
vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.592444
GSE217363_0_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131887_1_v_4_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPI1-23127762-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86531
NCIH2342	CCLE Cell Line Gene CNV Profiles	1.0	1.41388
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2262_KO_Uhrf2_SRP105534	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.16343
SUZ12_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_6496_KD_PIEZO1_SRP392492	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Unnamed_4_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE113734_3_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01254
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
OCI-AML3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.94013
abnormality of head or neck	HPO Gene-Disease Associations	1.0	null
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.824625
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.915192
hsa-miR-3613-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
Ureteral disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.57459
ventral posterior parvicellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45586
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05075
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880116
r9 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68038
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.967315
hsa-miR-4695-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39922
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02139
PMC9170821-JCMM-26-3183-s001.xlsx-Oligo_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38249
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31893
NCIH23	CCLE Cell Line Gene CNV Profiles	-1.0	-2.35108
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_13056_Mut|OE_Sik3E13_SRP334442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.7515
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19512
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.517
GSE98360,GSE98362_1_v_0_uhrf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.90321
Exudative vitreoretinopathy 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.502
RDES	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65151
JAK2_knockout_79_GSE26188	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.86783
TJP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36916
LC1F	CCLE Cell Line Gene CNV Profiles	1.0	1.44031
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09625
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53074
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30412
hsa-miR-562	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
absent inner hair cell stereocilia	MGI Mouse Phenotype Associations 2023	1.0	null
FBRSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.82069
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07979
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.69029
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13247
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23411
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_5586_KO_RELA_SRP149723	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.13239
ZSCAN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34798
Perturb_15661_KD_Hnrnpc_SRP313287	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.15014
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33367
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.194
Spontaneous preterm birth without premature rupture of membranes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
superficial stratum of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14269
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-SYMBOL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
posterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07832
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878188
sensory system disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830762
reticular formation of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26603
Dorsal part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09827
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13263
slc7a14	GeneRIF Biological Term Annotations	1.0	null
Ventral posteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30394
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75247
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.918177
LASV_FML29_24hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.782046
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMARCA4	ChEA Transcription Factor Targets	1.0	null
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01988
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4858-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12263605-DataSheet1.pdf-415-LIN54_LIN54	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_4868_KO_NEUROG3_ERP110708	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.638
NR4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98694
hsa-miR-4426	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE102505_1_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Retinitis pigmentosa 46	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.483
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041766
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07946
Bardet-Biedl syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10732
acidic amino acid transport	GO Biological Process Annotations 2025	1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.975426
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11634
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
SCH	DepMap CRISPR Gene Dependency	1.0	5.9979
PCBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82878
PMC8012850__F6	PFOCR Pathway Figure Associations 2023	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-520g	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59697
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38708
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.253
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02117
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KPNRTBM1	CCLE Cell Line Gene Expression Profiles	1.0	2.05695
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31181
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95836
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.2137
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27226
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00677
GSE155031_6_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-N7MT-0011-R2a-SM-2I3GI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37791
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Eye-retinal bipolar neuron	Tabula Sapiens Gene-Cell Associations	1.0	1.05022
ZNF827	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2594
HARA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CAOV3	DepMap CRISPR Gene Dependency	1.0	2.80571
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52688
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1897	CCLE Cell Line Gene CNV Profiles	1.0	1.60263
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.878627
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
GARIN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03629
ANKRD40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08186
C8G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13904
HCC15	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83638
glis3_19805515_embryonic_pancreas_lof_mouse_gpl1261_gds3812	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.458367
G0S2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29604
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65353
KCNK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64137
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2642
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04185
IFNGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52613
U-698-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
AATF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51002
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15218
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
hearing abnormality	HPO Gene-Disease Associations	1.0	null
hsa-miR-3148	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HT55	DepMap CRISPR Gene Dependency	1.0	2.12332
Dentate gyrus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63976
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.824248
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16387
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2988
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nephronophthisis 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072473
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4766-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
hsa-miR-4711-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6238
MAX	ENCODE Transcription Factor Targets	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.22566
U2OS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54921
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.73655
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47034
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16627
A-CA-04-2009(H1N1)_48Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.88021
GSE77108_0_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
JcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1852
lateral superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40874
Hyperekplexia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.39
USP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10302
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.57499
obesity	HPO Gene-Disease Associations	1.0	null
Mouse - Motor Cortex - Cluster - vascular lepotomeningeal cell_7	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE224294_3_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the penis	HPO Gene-Disease Associations	1.0	null
hsa-miR-4429	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
Restless legs syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.764
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.77986
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01706
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4264	TargetScan Predicted Conserved microRNA Targets	1.0	0.059817
H3K27me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.46794
DIFI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3910	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
anterior paraventricular nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55094
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3120-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Amaurosis	DisGeNET Gene-Disease Associations	1.0	null
H3K27me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
GSE223008_9_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.302698
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872062
H3K27me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-548ah	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29921
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21857
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14084
abnormality of the cornea	HPO Gene-Disease Associations	1.0	null
H3K27me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5385_KO_Isl1_SRP380182	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.7212
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3373
abnormality of connective tissue	HPO Gene-Disease Associations	1.0	null
CTCF-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.712407
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PSMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45586
hsa-miR-1303	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
Type 1 diabetes mellitus_T lymphocyte_GSE10586	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.53698
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.13997
Perturb_8731_KD_HERV_SRP343980	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_5349_OE_Dux_SRP201141	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.3245
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.17311
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.26732
cSARS Bat SRBD_24Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.52542
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
STON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89636
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10939
POLR3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25646
single-organism transport	GO Biological Process Annotations 2015	1.0	null
Leber congenital amaurosis 14	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
TRMT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2267
outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.162763
VZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.985366
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CALCOCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49637
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054649
Paraventricular hypothalamic nucleus, magnocellular division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29798
SGCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39994
PMC6814198-NIHMS1538462-supplement-2.xlsx-Transitory_415genes-SNAI2_SNAI2	Rummagene Transcription Factor Associations 2026	1.0	null
malignant mesothelioma	GWASdb SNP-Phenotype Associations	1.0	0.408753
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0723
KYSE-180	COSMIC Cell Line Gene CNV Profiles	1.0	2.26395
abnormality of metabolism/homeostasis	HPO Gene-Disease Associations	1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86946
Leber Congenital Amaurosis	DisGeNET Gene-Disease Associations	1.0	null
pleural mesothelioma	GWASdb SNP-Phenotype Associations	1.0	0.949798
TYSND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17416
Pathologic nystagmus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
hsa-miR-495	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
nucleus subceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.893574
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-Fay_Heat_LPStoThermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
retinitis pigmentosa	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.10313
cholesterol, hdl	GAD Gene-Disease Associations	1.0	null
hsa-miR-3139	TargetScan Predicted Conserved microRNA Targets	1.0	0.078844
cd8.Tcell	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.847677
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10988
Nucleus of the optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55482
BFTC905	DepMap CRISPR Gene Dependency	1.0	4.56842
vacuole	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
496100516_FWM_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.12989
PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4480	TargetScan Predicted Conserved microRNA Targets	1.0	0.015875
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Retinal cone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.226
submedius thalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.52833
Motor nucleus of trigeminal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4211
Sensorineural Hearing Loss (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
Male reproductive system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.939
KYSE-450	COSMIC Cell Line Gene Mutation Profiles	1.0	null
retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.239799
Bardet-Biedl syndrome 20	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.44
WM983B	DepMap CRISPR Gene Dependency	1.0	2.32408
COLO792	DepMap CRISPR Gene Dependency	1.0	3.12597
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12158
KRBOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21701
NCIH2066	CCLE Cell Line Gene Expression Profiles	1.0	1.40547
NCIH510	CCLE Cell Line Gene Expression Profiles	1.0	1.75451
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.957325
THOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17667
superficial stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5802
GSE77108_5_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
MSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51117
RPP38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47311
GSE233679_5_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4775	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6602
HDAC2	ENCODE Transcription Factor Targets	1.0	null
MED20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65809
MDST8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ESRRB-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SHP77	CCLE Cell Line Gene Expression Profiles	1.0	1.59624
intermediate stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05028
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29438
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.9287
GSE210101,GSE210114_6_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MAX_KO_TESTES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE155031_6_v_2_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.913052
mediates	GeneRIF Biological Term Annotations	1.0	null
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.538
KYSE180	CCLE Cell Line Gene CNV Profiles	1.0	1.36148
r2 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02319
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.352227
TP63	ChEA Transcription Factor Targets	1.0	null
Perturb_4158_KO_Mir137_SRP072457	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.5587
ACAD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.6861
primary visual cortex (striate cortex, area V1/17)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05844
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042248
hsa-miR-4662b	TargetScan Predicted Conserved microRNA Targets	1.0	0.002088
Mesothelioma_MESO_TCGA-MQ-A4LP-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13054_OE_HDAC4_SRP334442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.5513
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Eye disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.775
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	189.942
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043604
GSE226249_2_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
establishment of localization	GO Biological Process Annotations 2015	1.0	null
hsa-miR-548aa	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EIF3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08316
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.959629
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.888296
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977863
NRL_Deficiency_GDS1693_238_mouse_Photoreceptors cells of retinas at P10	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PPARG-20176806-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4709-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
Bardet-Biedl syndrome 21	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.501
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.841599
medial group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27619
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
Retinitis pigmentosa	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18383
Cytoplasmic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.829
NANOG-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1623	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OCUG1	DepMap CRISPR Gene Dependency	1.0	5.1891
KKU213	DepMap CRISPR Gene Dependency	1.0	4.2322
GSE129241_4_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.8067
hsa-miR-4794	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07908
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9me3_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29591
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1684
ADA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2103
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1048	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3825
COLO668	CCLE Cell Line Gene Expression Profiles	1.0	1.71339
DAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16095
Ventral anterior-lateral complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48926
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Male reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.939
PRKAR2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11557
FOXD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03549
RPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16936
outer SZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.838379
GSE112760,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STAT3-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857629
WDR81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74198
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.56575
TAF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3456
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
synapse part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.075271
APP_KO_GDS4414_370_mouse_prefrontal cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
REST_01_145	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.02737
hsa-miR-1299	TargetScan Predicted Conserved microRNA Targets	1.0	0.02452
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.7061
hsa-miR-4484	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
suggests	GeneRIF Biological Term Annotations	1.0	null
GTEX-OHPN-0011-R9A-SM-4DXUH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88384
GSE154936_3_v_4_remdesivir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-125a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
ANKRD54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69776
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
496100463_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.20329
Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31138
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17752
REST_Panc1_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eye and adnexa disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
ZNF740	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	112.065
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897172
EPHB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70273
ESR1-22446102-UTERUS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
REST_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18257
abnormal eye electrophysiology	MGI Mouse Phenotype Associations 2023	1.0	null
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.4139
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-421	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41284
A388	COSMIC Cell Line Gene CNV Profiles	1.0	2.26395
periventricular stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18395
Breast Cancer_Mammary Gland Tissue_GSE3744	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.18144
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14561
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33626
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840481
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3588
inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051197
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
neoplasm of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.333011
FKBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01033
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14439
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6956-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6155
transport	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-323-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.959629
short-rib thoracic dysplasia 10 with or without polydactyly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
Retinitis pigmentosa 54	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
MON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74867
Retinitis pigmentosa 89	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
hsa-miR-513a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.165047
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03765
ZNF229	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40524
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226249_0_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CPNE7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06857
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970628
Retinitis pigmentosa 68	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.262
hsa-miR-3613-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
Rod photoreceptor outer segment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.154
MED19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57602
hypoplasia of penis	HPO Gene-Disease Associations	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6907-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.874715
REST_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51069
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7288-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6040_KD_MRTO4_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.38998
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CAL-39	COSMIC Cell Line Gene CNV Profiles	1.0	2.26395
periventricular stratum of p3ZL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08135
hsa-miR-922	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04606
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.8507
Perireunensis nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5237
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89024
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847727
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16118
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.73076
GTEX-N7MT-0011-R3a-SM-2I3GC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29216
Retinal degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.02
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10504
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07885
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34476
connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.210589
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-3646	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16627
H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MT-CO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40557
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169617_1_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33619
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00677
KIAA0319L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07073
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE153064,GSE153065_1_v_2_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38132
r6 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34561
496100551_PCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.0564
REST	ChEA Transcription Factor Targets	1.0	null
ELF3-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Retinitis pigmentosa 45	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
Cationic amino acid transporter, C-terminal	InterPro Predicted Protein Domain Annotations	1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34561
Brain Lower Grade Glioma_LGG_TCGA-S9-A7J1-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.719
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32438
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4742-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963486
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82954
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R9A-SM-32PLV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68483
Brain Lower Grade Glioma_LGG_TCGA-HT-7616-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57585
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57656
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960698
SEC14L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09079
VIRMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2249
Retinitis pigmentosa 42	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.497
PMC7941712-40478_2021_1135_MOESM12_ESM.xlsx-Table_S4D_DEG_ST-EPN-RELA-Unnamed_6_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.32941
PMC4051124-1471-2164-15-256-S15.XLSX-WES_IPD-RBCK1_1-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26532
PGBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05637
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZDHHC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05143
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE188721_3_v_1_mesp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56022
BEN	CCLE Cell Line Gene Expression Profiles	1.0	1.52991
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE226249_0_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.47289
hsa-miR-4678	TargetScan Predicted Conserved microRNA Targets	1.0	0.092495
496100337_HIP_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.40835
MFE-280	COSMIC Cell Line Gene CNV Profiles	1.0	2.26395
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.948249
cationic	GeneRIF Biological Term Annotations	1.0	null
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28616
nfe2l2_18059474_liver_lof_mouse_gpl1261_gds3406	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.118395
GSE187006_0_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.959629
H3K27me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ECC10	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54044
Retinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.024
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.04734
Fundus dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.853
NOCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.923
hsa-miR-1263	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3K_Peaks_wtYAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.01
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.890705
hsa-let-7d	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
Disease of cellular proliferation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.939
autosomal recessive inheritance	HPO Gene-Disease Associations	1.0	null
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11745
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.3292
TEAD4_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988265
Stargardt disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
posteroventral (inferior) parietal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.943206
NCIH1373	DepMap CRISPR Gene Dependency	1.0	2.98104
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0723
OCT4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the optic nerve	HPO Gene-Disease Associations	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3624
hsa-miR-345	TargetScan Predicted Conserved microRNA Targets	1.0	0.31417
CDK8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44164
MCF7	DepMap CRISPR Gene Dependency	1.0	3.32765
SF3A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00917
Retinitis pigmentosa 26	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854352
medial parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.833087
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.9202
PTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38169
SCAMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7315
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879479
GSE102505_6_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-211	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
DDX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60325
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.891592
KDM1A	ENCODE Transcription Factor Targets	1.0	null
REST_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12959
GSE77108_0_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
regulation of phosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
Atypical Scarring Of Skin	DisGeNET Gene-Phenotype Associations	1.0	null
MFN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95916
lytic vacuole membrane	GO Cellular Component Annotations 2025	1.0	null
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872077
superficial stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.47867
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4251	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050687
Disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
ARMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67096
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8334-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.969
Lysosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SNU626	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63273
regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
Inner plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.902
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMCH1	DepMap CRISPR Gene Dependency	1.0	2.34108
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JN-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.831458
BFTC-905	COSMIC Cell Line Gene CNV Profiles	1.0	2.26395
lateral habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.22477
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042797
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Horizontal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.048
IMMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4008
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Peroxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.669
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10106
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.06313
r8 part of nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07783
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_72h_1-Unnamed_0_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-612	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
KOSC2	DepMap CRISPR Gene Dependency	1.0	3.28797
TBX4-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31544
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89404
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.52675
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4700-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66171
Myopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
amino acid transport	GO Biological Process Annotations 2023	1.0	null
GSE77108_8_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-586	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
TE4	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58299
CHURC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65349
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15104
hsa-miR-128	TargetScan Predicted Conserved microRNA Targets	1.0	0.283838
r7 part of nucleus prepositus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13089
ae3	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.537
Leukodystrophy disease specific cell type	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.645
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Blastocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.995
hsa-miR-4426	TargetScan Predicted Conserved microRNA Targets	1.0	0.003282
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2626
hsa-miR-660	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
HMGN2_02_20	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.42626
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21391
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960735
Perturb_16507_OE_Rest_SRP314492	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Keratoconus	DisGeNET Gene-Disease Associations	1.0	null
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.566
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16527
CTCF	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55361
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Proteasome core complex, alpha-subunit complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.221
Perturb_8899_KD_IQGAP3_SRP359044	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE169263_1_v_0_armc5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
visual field defect	HPO Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-5962-01B-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.989509
cSARS Bat SRBD_30Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.38826
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ARPE-19 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.766
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827562
MMAC	DepMap CRISPR Gene Dependency	1.0	2.00223
hsa-miR-182	TargetScan Predicted Conserved microRNA Targets	1.0	0.02452
GSE224969,GSE224971_0_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68102
negative regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
abnormal pyramidal signs	HPO Gene-Disease Associations	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938345
hsa-miR-4769-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K9me3_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ULK1	Kinase Library Serine Threonine Kinome Atlas	1.0	null
lateral medullary reticular group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24028
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19424
NCIH854	CCLE Cell Line Gene CNV Profiles	1.0	1.91994
leber hereditary optic neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.04293
Cystic Fibrosis_Lung_GSE3100	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.97645
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MCM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34846
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12240782-Table3.xlsx-Sheet1-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
TNFAIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40982
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90579
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28221
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.959629
abnormality of the posterior segment of the eye	HPO Gene-Disease Associations	1.0	null
r3 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12837
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.181607
GSE210101,GSE210114_2_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF596	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43906
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5839
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R9-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BICR18	CCLE Cell Line Gene CNV Profiles	1.0	1.50882
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054365
PHOX2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46834
mRNA_POU5F1_20526341	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Ribbon synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.519
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-204	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
RBBP5	ENCODE Transcription Factor Targets	1.0	null
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4725-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
MED30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46039
IKZF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10172
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-326	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
Optic disk drusen	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.4092
CAPAN-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.26395
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98703
Muscle - Skeletal	GTEx Tissue Gene Expression Profiles 2023	1.0	1.66035
SIN3B	ChEA Transcription Factor Targets	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
NCIH1694	CCLE Cell Line Gene Expression Profiles	1.0	1.9525
Perturb_1075_KO_Il17a_ERP107271	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.08822
SCN4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3422
growth abnormality	HPO Gene-Disease Associations	1.0	null
SHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22173
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00575
Vestibular sensory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.259
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.63637
GSE77108_3_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16439
KLF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5716
Optic Atrophy	DisGeNET Gene-Disease Associations	1.0	null
GSE89032,GSE89033_0_v_1_sfpq_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.965171
PMC6117931-12864_2018_5033_MOESM3_ESM.xlsx-BrtoFay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23456
KBTBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23144
NICN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07455
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Outer plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.32
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07865
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DMS79	CCLE Cell Line Gene Expression Profiles	1.0	1.85396
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.87163
ENY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65098
hsa-miR-4668-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE174701_1_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.996643
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.94424
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98031
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17281
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-122	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10745
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
carboxylic acid transmembrane transporter activity	GO Molecular Function Annotations 2023	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18257
type ii diabetes mellitus	HPO Gene-Disease Associations	1.0	null
organelle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.068498
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
m1 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56453
Retinitis pigmentosa 69	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.421
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
METTL25B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17411
Perturb_5882_KD_EZH2_SRP106792	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Infective endocarditis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.282
epididymis	HPA Tissue Protein Expression Profiles	1.0	0.821089
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.26267
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14433
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.07518
GSE206093,GSE206094_1_v_0_isl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100448_TCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.2363
nystagmus	HPO Gene-Disease Associations	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Oligo_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-545	TargetScan Predicted Conserved microRNA Targets	1.0	0.082179
NCI-H211	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34166
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59637
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30482
ESYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54916
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
496100461_PCx_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.65273
NCIH1092	CCLE Cell Line Gene Expression Profiles	1.0	1.64627
SMARCA4-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3658	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Lytic vacuole	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01611
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.059156
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35719
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38109
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC12211354-12915_2025_2224_MOESM6_ESM.xlsx-Sheet1-Sheet1_The_source_list_of_zebrafish_Npas4b_targets_from_human_NPAS4_targets_in_CHEA3_database_NPAS4	Rummagene Transcription Factor Associations 2026	1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.49835
ear	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.445268
Hailey-Hailey disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59506
MFE280	CCLE Cell Line Gene CNV Profiles	1.0	1.86096
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3491
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the genitourinary system	HPO Gene-Disease Associations	1.0	null
Triangular nucleus of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26497
SKCO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44376
ZNF174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30712
abnormality of vision	HPO Gene-Disease Associations	1.0	null
Perturb_3502_KO_Tmem106b_SRP249535	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.97964
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Hyperekplexia 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.463
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
Neuroendocrine cell_Trachea_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5124
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06668
ZNF148	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	131.04
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1488
hsa-miR-320a	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11895
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-194	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K27me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20259
GSE210101,GSE210114_2_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96435
RNF44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44156
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.964594
FOXP1	ChEA Transcription Factor Targets	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42446
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8424-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cholesterol, HDL	dbGAP Gene-Trait Associations	1.0	0.32177
PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_4_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TRIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20918
REST_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88206
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.840479
hsa-miR-3673	TargetScan Predicted Conserved microRNA Targets	1.0	0.099701
HROB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58456
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-S_48h_1-Unnamed_0_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042471
Pancreas-pancreatic beta cell	Tabula Sapiens Gene-Cell Associations	1.0	1.53734
NCIH2171	CCLE Cell Line Gene Expression Profiles	1.0	3.40781
hsa-miR-502-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.800582
abnormal rod electrophysiology	MGI Mouse Phenotype Associations 2023	1.0	null
Endocarditis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.159
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36512
dorsolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.835029
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7151
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11879
JPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58441
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09981
C33A	DepMap CRISPR Gene Dependency	1.0	2.1642
CEBPB	ENCODE Transcription Factor Targets	1.0	null
Retinitis pigmentosa 72	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.487
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03285
SKMEL19	DepMap CRISPR Gene Dependency	1.0	4.41612
SIMA	CCLE Cell Line Gene Expression Profiles	1.0	1.91855
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GRM	CCLE Cell Line Gene CNV Profiles	-1.0	-2.85696
cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.519575
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24535
CHD7	ENCODE Transcription Factor Targets	1.0	null
NOC3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01611
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62521
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.842405
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC4686057-pone.0145107.s001.xlsx-PAA-CAA-Unnamed_0_TSHZ1	Rummagene Transcription Factor Associations 2026	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.62854
REST_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24224
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.49345
Retinitis pigmentosa 47	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4641
hsa-miR-1262	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16642
GSE80446_2_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4456	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HMGXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70038
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Modiolus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.979
ventral posteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41029
Spastic tetraplegia, thin corpus callosum, and progressive microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.351
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06626
negative regulation of biological process	GO Biological Process Annotations 2015	1.0	null
anion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2736
HDAC1	ENCODE Transcription Factor Targets	1.0	null
Intermediodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14476
REST_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gamma-aminobutyric acid transport	GO Biological Process Annotations 2025	1.0	null
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4789-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
cortico-medial group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.888179
Cataract	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.992579
CLDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22751
CV-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.704
SAP30	ENCODE Transcription Factor Targets	1.0	null
GSE226249_0_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1265
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.0511
hsa-miR-491-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
LXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary auditory cortex (core)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11343
gamma-aminobutyric acid import	GO Biological Process Annotations 2025	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74561
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WL-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0046
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.971666
hsa-miR-1283	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13269
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OTOL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15598
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18257
Atrophic Retina	DisGeNET Gene-Disease Associations	1.0	null
Perturb_15240_KD_ERCC6L2_SRP349996	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.70969
visual pathway disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.624927
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
B4GALT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66424
Leber congenital amaurosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.697
Ornithine carbamoyltransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.581
malignant mesothelioma	GWASdb SNP-Disease Associations	1.0	1.085
PMC8384902-mmc6.xlsx-DEG_ASCL1_3TF_shared-GeneSymbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30562
Brain Lower Grade Glioma_LGG_TCGA-DB-5279-01A-03R-2347-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7445411-CPR-53-e12862-s006.xlsx-Sheet1-Supplementary_Table_S4_Gene_expression_profiling_of_NT-MSC_and_III-MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.57811
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.889317
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_12_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4726-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
SSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55587
MARCHF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01654
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1857
monocarboxylic acid transmembrane transporter activity	GO Molecular Function Annotations 2025	1.0	null
Globoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.645
BGC823	CCLE Cell Line Gene CNV Profiles	1.0	1.52947
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09345
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33976
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
malignant pleural mesothelioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.798692
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.459532
periventricular stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23303
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01611
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833493
NANOG-16518401-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE250534_2_v_3_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MBNL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91583
abnormality of the eye	HPO Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6668-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EK-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Arsenic	CTD Gene-Chemical Interactions	1.0	null
abnormality of central motor function	HPO Gene-Disease Associations	1.0	null
hsa-miR-4729	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.92703
globe disease	DISEASES Curated Gene-Disease Association Evidence Scores	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55403
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5437
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41371
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of the retinal vasculature	HPO Gene-Disease Associations	1.0	null
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47339
LN319	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78182
Amino acid/polyamine transporter I	InterPro Predicted Protein Domain Annotations	1.0	null
hsa-miR-1287	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
arginine	GeneRIF Biological Term Annotations	1.0	null
FU97	DepMap CRISPR Gene Dependency	1.0	3.00133
SNU349	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64362
hsa-miR-548z	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
IQCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00565
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Night blindness	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.76
Glycinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.13
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26424
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	2.19034
fused inner hair cell stereocilia	MGI Mouse Phenotype Associations 2023	1.0	null
Cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
Tfcp2l1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.506
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09697
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00141
TEAD4	ENCODE Transcription Factor Targets	1.0	null
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.72891
Cochlear ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.99
NCI-H1993	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50053
hsa-miR-4778-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.071548
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.848103
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
PMC9578714-elife-81083-supp2.xlsx-AA_Transporters-Gene_Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Vacuolar membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ESR1	ChEA Transcription Factor Targets	1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05305
DMRTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10886
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54434
BICR22	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Reproductive organ cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.939
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-3200-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
GSE77108_6_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.192
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18257
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838992
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9385
hsa-miR-548d-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
hsa-miR-4477a	TargetScan Predicted Conserved microRNA Targets	1.0	0.199275
P300-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZDHHC23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32207
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08981
FOXP2-21765815-NEURO2A-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC12178937-mmc6.xlsx-L_MAFF_KDvsL_C_deg_all-gene_id_MAFF	Rummagene Transcription Factor Associations 2026	1.0	null
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22473
slc7a2	GeneRIF Biological Term Annotations	1.0	null
JHUEM3	CCLE Cell Line Gene Expression Profiles	-1.0	-2.02168
Dentate gyrus, granule cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74453
Conductive Hearing Loss	DisGeNET Gene-Disease Associations	1.0	null
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-5394-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22724
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PPARD	ChEA Transcription Factor Targets	1.0	null
Dehydrodolichyl diphosphate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.62
lateral group of nuclei, left, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11514
KLF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	89.1768
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16199
GSE84148,GSE96938_0_v_2_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.882346
r5 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1547
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.08008
RT-112	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_6497_KD_PIEZO1_SRP392492	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
anterior pretectal nucleus, dorsal superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.24462
ventral reuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.57618
Anterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03087
GSE184892_7_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.42467
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07898
H3K27me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46B-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased corneal thickness	HPO Gene-Disease Associations	1.0	null
NCIH446	DepMap CRISPR Gene Dependency	1.0	5.71745
anterior cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16496
SRRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12779
PMC4590705-13062_2015_86_MOESM1_ESM.xlsx-Gene_A_-_TP53-Unnamed_8_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11061611-cd-23-0857_table_s4_suppst4.xlsx-Epithelial_B-pEpi13_B_shared_FU1_ASCL1_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.915023
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Macular degeneration	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
Lateral posterior nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.65852
SLC12A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24027
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14109
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lysosome	GO Cellular Component Annotations 2025	1.0	null
HSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65506
Mesothelioma	DisGeNET Gene-Disease Associations	1.0	null
UMUC14	DepMap CRISPR Gene Dependency	1.0	3.6644
CRY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94589
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05657
hsa-miR-590-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877886
VAV1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08002
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-let-7a	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
nitrogen compound transport	GO Biological Process Annotations 2023	1.0	null
PTPRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41946
membrane	GO Cellular Component Annotations 2015	1.0	null
superficial stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31026
UBF1/2-26484160-CHIP-SEQ-HMEC-DERIVED-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3048
hsa-miR-3647-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226249_0_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
EIF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36988
ATP5MG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15039
ovary	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.955326
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857126
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.92628
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3999
Congenital Hypoplasia Of Penis	DisGeNET Gene-Disease Associations	1.0	null
Electroretinogram Abnormal	DisGeNET Gene-Phenotype Associations	1.0	null
Lassa Fever Virus_4hr_24069471_GSE41300	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.00738
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
COLO-741	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10373
Sensory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.761
KELLY	CCLE Cell Line Gene Expression Profiles	1.0	1.48758
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2227	CCLE Cell Line Gene Expression Profiles	1.0	1.40069
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC4A1AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8218
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.90285
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.35521
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
Pancreatic alpha cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49362
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11056
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.947826
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10152
PMC10684515-41467_2023_43264_MOESM7_ESM.xlsx-HOXA9_ChIP-seq_peaks_in_SEM-Closest_Gene_HOXA9	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-875-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.011888
hsa-miR-1273d	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
hsa-miR-1273g	TargetScan Predicted Conserved microRNA Targets	1.0	0.111118
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.38229
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
Renal tubule epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.88
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.916766
Brain Lower Grade Glioma_LGG_TCGA-HT-8105-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Submedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.28518
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.912455
Microbody membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.669
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.83395
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17942
RPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59842
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.826639
KDM4A	ENCODE Transcription Factor Targets	1.0	null
MT-ND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3587
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
CBX3	ENCODE Transcription Factor Targets	1.0	null
Perturb_12858_KO_Ift88_SRP125630	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.57579
Neural retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.178
CLDN34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13515
GSE155031_6_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
Central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.764
S1PR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62654
ATP5ME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77994
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907865
PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-453-HIC2_HIC2	Rummagene Transcription Factor Associations 2026	1.0	null
negative regulation of dephosphorylation	GO Biological Process Annotations 2015	1.0	null
H3K9me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
WDR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12395
gigantocellular group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.953994
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-374b	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59363
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07697
THRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30206
H3K27me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-433	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.7645
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4789-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19629
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AL-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBPMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94237
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51171
NCIH1755	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44358
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
H3255	COSMIC Cell Line Gene CNV Profiles	1.0	2.26395
organic anion transport	GO Biological Process Annotations 2015	1.0	null
Cystoid macular edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
Brain Lower Grade Glioma_LGG_TCGA-DU-7302-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6847
ALG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15988
superficial stratum of r5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05198
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45445
GSE236437_2_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBC1D15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52284
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81147
KYSE-220	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cystinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.882
RCM1	DepMap CRISPR Gene Dependency	1.0	2.78847
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842619
hsa-miR-202	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE30	DepMap CRISPR Gene Dependency	1.0	3.248
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KCNE5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28613
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36619
decreased inner hair cell stereocilia number	MGI Mouse Phenotype Associations 2023	1.0	null
GSE111660_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lens disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.053
hsa-miR-4430	TargetScan Predicted Conserved microRNA Targets	1.0	0.088999
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.959629
Perturb_16637_KO_Drd2m_SRP377988	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.781
r6 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16071
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994211
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04558
hsa-miR-4646-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
SK-MEL-28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.870076
hsa-miR-3187-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548ad	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
GTEX-RNOR-0011-R9A-SM-2TF52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61662
REST_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6793-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60923
LC-1-SQ	COSMIC Cell Line Gene CNV Profiles	1.0	2.26395
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17616
Mpf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.573
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6060_KD_RBMX_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.40939
PMC12178937-mmc6.xlsx-D_MAFF_KDvsD_C_deg_all-gene_name_MAFF	Rummagene Transcription Factor Associations 2026	1.0	null
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.31006
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.31495
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
phenotypic abnormality	HPO Gene-Disease Associations	1.0	null
ZNF433	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94717
POLR2A	ENCODE Transcription Factor Targets	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
ATP7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50796
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
IRS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95357
KDM5A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Retinal edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
Usher syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.774
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00619
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05465
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.63057
PRIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19199
Ventral posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17415
Hereditary retinal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
Outer hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.384
T47D	CCLE Cell Line Gene CNV Profiles	1.0	1.43533
r8 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20186
organelle outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.340773
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE225901_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34001
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R7A-SM-2HMJP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08431
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-4795-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
periventricular stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01526
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18383
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04965
decreased total retina thickness	MGI Mouse Phenotype Associations 2023	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NHOK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
brain	HPA Tissue Gene Expression Profiles	1.0	1.90694
superficial stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41288
ChIP_H3K27me3_20682450_humanESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NLGN3_KD_GDS4759_336_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89796
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11579
Perturb_15770_KO_Uxt_SRP240277	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Iminoglycinuria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.569
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE187006_3_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-0.95242
r3 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01722
PMC7862469-13238_2020_779_MOESM4_ESM.xlsx-FOXO3-GE_VS_WT-GeneID_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57912
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07392
abnormality of the fundus	HPO Gene-Disease Associations	1.0	null
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.976758
Nervous system disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858417
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SMAD1-26771354-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
SNAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2409
intermedioposterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67912
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4438	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
Foveal hypoplasia 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
centromedian nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10905
amino acid transport	GO Biological Process Annotations 2025	1.0	null
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.967666
GTEX-NL4W-0011-R9a-SM-2I3G1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52892
abnormality of circulating hormone level	HPO Gene-Disease Associations	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.44599
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CNMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36134
Perturb_9072_KD_SEPTIN2_SRP288211	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.36574
PMC5798892-41421_2017_3_MOESM8_ESM.xlsx-down-regulated-Supplementary_Table_S3_Up-_and_downregulated_genes_in_ATF6-_-_hMSCs_compared_to_ATF6_hMSCs_late_passage_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.46268
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
parathyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.821089
inner SZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.999755
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE245270_2_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ERCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03808
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SB-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mitochondrial crista	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.806148
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-ENSEMBL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
Hyperinsulinism	DisGeNET Gene-Disease Associations	1.0	null
ATXN7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29678
KLF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.4912
hsa-miR-4796-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.082179
dorsal part of CoP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19582
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
GSE102467_1_v_0_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CENPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18717
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF311	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32358
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29872
GTEX-WL46-0011-R9A-SM-3MJFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71841
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
SDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76434
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-1.50784
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.949271
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07312
Adrenocortical carcinoma_ACC_TCGA-OR-A5JV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.49366
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19933
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8386
Amino acid transport complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.632
transporter	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-2110	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043384
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.91729
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
abnormality of the nervous system	HPO Gene-Disease Associations	1.0	null
Intraciliary transport particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.66
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6887651-Table_1.xlsx-Sheet1-SRY_SRY	Rummagene Transcription Factor Associations 2026	1.0	null
STAT3-24763339-IMN-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
retinal	GeneRIF Biological Term Annotations	1.0	null
head of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17825
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MF-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PXMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.55945
hsa-miR-4470	TargetScan Predicted Conserved microRNA Targets	1.0	0.011888
cSARS Bat SRBD_60Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.44553
GTEX-NPJ7-0011-R2a-SM-2I3GF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49967
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12214
NRROS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65491
hsa-miR-4430	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
hsa-miR-613	TargetScan Predicted Conserved microRNA Targets	1.0	0.065994
TE-6	COSMIC Cell Line Gene CNV Profiles	1.0	2.26395
hsa-miR-3919	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944262
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975797
MTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48832
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10589
hsa-miR-623	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.788964
RCOR3	ChEA Transcription Factor Targets	1.0	null
NUBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79997
molecular layer of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6087
Brain Lower Grade Glioma_LGG_TCGA-HW-7491-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
absent cochlear inner hair cells	MGI Mouse Phenotype Associations 2023	1.0	null
GSE113734_1_v_2_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.83243
hsa-miR-3609	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H3K36me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal external genitalia	HPO Gene-Disease Associations	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.13825
retinitis pigmentosa	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.591727
Perturb_560_KD_MYO1C_SRP158445	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	19.5229
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.939
arl6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.019
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
globe disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.302337
Nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99788
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64405
SEC23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6145
hyperinsulinemia	HPO Gene-Disease Associations	1.0	null
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30562
SRY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.31332
Abdominal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
PMC4387713-supp_gad.255984.114_Table_S3.xlsx-S3A-Down_Dpy30_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27205
Vacuole	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46893
LYSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53489
GSE118816_0_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36732
primary somatosensory cortex (area S1, areas 3,1,2)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.898974
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8989
KDM5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40401
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01546
PMC9843885-40478_2023_1507_MOESM6_ESM.xlsx-CIC-OE_TS603-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Blindness	DisGeNET Gene-Phenotype Associations	1.0	null
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	1.14017
GANAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13057
Gyrate atrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.486
INSM1_Deficiency_GDS5066_272_mouse_Fetal pituitary glands from embryonic day 17.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NR3C1-34362910-WISTARRAT-HIPPOCAMPUS-STRESS	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_9200_KD_EZH2_SRP319833	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H2BC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14896
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Photoreceptor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.666
intermediate stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15985
hsa-miR-374a	TargetScan Predicted Conserved microRNA Targets	1.0	0.078844
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28014
retroreuniens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84441
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.159
KMBC2	DepMap CRISPR Gene Dependency	1.0	2.36787
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80826
Perturb_6957_KO_Ift88_SRP179473	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.57579
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.941642
Bothnia retinal dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.356
CAL-85-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.26395
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02889
GSE217363_4_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5697-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54394
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
TP53INP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50587
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.046667
PMC10661700-41525_2023_383_MOESM2_ESM.xlsx-Supp_Table3_WBBC_GCR-SYMBOL_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905147
hyperreflexia	HPO Gene-Disease Associations	1.0	null
hsa-miR-4271	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00677
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12224
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retinal disease	DISEASES Curated Gene-Disease Association Evidence Scores 2025	1.0	4.0
NAGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39029
MAPRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16959
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG	ChEA Transcription Factor Targets	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4307	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
PDLIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57611
Prostate adenocarcinoma_PRAD_TCGA-FC-A8O0-01A-41R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.093591
abnormal eye physiology	HPO Gene-Disease Associations	1.0	null
DARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19175
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.965488
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838976
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18258
REST_01_337	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.65054
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05929
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.953126
glaucoma	HPO Gene-Disease Associations	1.0	null
EZH2-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
p1 portion of the paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59682
GSE128844_0_v_1_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAKI2	DepMap CRISPR Gene Dependency	1.0	2.6704
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
paraventricular nucleus, cap part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26461
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS-STRESS	ChEA Transcription Factor Targets 2022	1.0	null
anteverted nares	HPO Gene-Disease Associations	1.0	null
Rheumatoid arthritis disease specific fibroblast-like synoviocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.537
Macular retinal edema	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
MOV10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64542
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11905
hsa-miR-5096	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Nasal Bridge Wide	DisGeNET Gene-Phenotype Associations	1.0	null
GSE216274,GSE216292_4_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1002
hsa-let-7e	TargetScan Predicted Conserved microRNA Targets	1.0	0.069137
PDIA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2039
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22473
EFE184	DepMap CRISPR Gene Dependency	1.0	3.61366
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.72427
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3339
ion transport	GO Biological Process Annotations 2015	1.0	null
Organ system cancer	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.939
Rod-Cone Dystrophy	DisGeNET Gene-Disease Associations	1.0	null
ZNF418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09271
H3K27me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-330-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
JcP contribution to LTL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18297
hsa-miR-4643	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
hsa-miR-4690-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
HL-60	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the retinal pigment epithelium	HPO Gene-Disease Associations	1.0	null
NMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-3126-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KANK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76152
Ventral posteromedial nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07351
biological_process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-3074-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.011888
ZNF630	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59894
periventricular stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01311
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18383
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07066
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950585
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8194
organelle part	GO Cellular Component Annotations 2015	1.0	null
CTSV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35538
hsa-miR-520d-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18379
496100615_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0138
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.522
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09161
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ8-0011-R3a-SM-2HMIW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02699
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.856278
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56498
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0598
hsa-miR-506	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Retinitis pigmentosa 61	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
EP300	ENCODE Transcription Factor Targets	1.0	null
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22929
GSE113734_1_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25864
SNU119	CCLE Cell Line Gene CNV Profiles	1.0	2.07532
Hypoglossal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22117
retrohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4594
TM31	CCLE Cell Line Gene Expression Profiles	-1.0	-2.12454
EZH2	ChEA Transcription Factor Targets	1.0	null
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870415
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.527
DLG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71069
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.36983
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5986-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04676
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.896712
GTEX-P4PQ-0008-SM-48TDX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84157
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40577
ChIP_RCOR3_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RXRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34352
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98979
thiamine-responsive megaloblastic anemia syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
FTCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11532
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.828115
chorioretinal abnormality	HPO Gene-Disease Associations	1.0	null
benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041947
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39695
Microtubule bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.848
EP400	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73985
Retinitis pigmentosa 85	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.44
hsa-miR-4458	TargetScan Predicted Conserved microRNA Targets	1.0	0.065994
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.930031
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04424
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35973
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50223
PPM1J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74689
ABITRAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38894
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957886
REST_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DPP3_OE_GDS2653_650_human_IMR-32 neuroblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE247084,GSE247087_0_v_1_cdyl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H810	COSMIC Cell Line Gene CNV Profiles	1.0	2.26395
GABA-ergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.924
sensorineural hearing impairment	HPO Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IF-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08256
Inner ear vestibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.018
BT-20	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TOLEDO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886219
EBF1-22473956-BONE-MARROW-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.583
PMC10684515-41467_2023_43264_MOESM7_ESM.xlsx-HOXA9_ChIP-seq_peaks_in_SEM-Gene_2-50kb_HOXA9	Rummagene Transcription Factor Associations 2026	1.0	null
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.886219
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154081_3_v_0_sildenafil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04063
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07966
regulation of phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
Retinitis pigmentosa 56	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.359
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845172
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.99323
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLCPRF5	DepMap CRISPR Gene Dependency	1.0	3.68825
496100340_TCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.19005
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8554124-DataSheet2.XLSX-34-RFX3_RFX3	Rummagene Transcription Factor Associations 2026	1.0	null
Pancreas-pancreatic alpha cell	Tabula Sapiens Gene-Cell Associations	1.0	2.14624
CENPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09777
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938096
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.0876
Brain Lower Grade Glioma_LGG_TCGA-E1-5319-01A-01R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of phosphatase activity	GO Biological Process Annotations 2015	1.0	null
periventricular stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04416
REV3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55624
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869741
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.5345
Hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.11
GABPA	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4797-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.075559
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.73887
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915354
hsa-miR-124	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8407-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE6	CCLE Cell Line Gene CNV Profiles	1.0	1.58499
CNOT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58206
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE109285_3_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-HS-A5N8-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCE-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.26395
Leber hereditary optic neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11661
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.8469
CLPTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39108
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inner nuclear layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.358
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.02162
vacuolar membrane	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-382	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
Retinitis Pigmentosa	HuGE Navigator Gene-Phenotype Associations	1.0	null
EXOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99761
Adrenocortical carcinoma_ACC_TCGA-OR-A5L4-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06381
LC1SQSF	CCLE Cell Line Gene CNV Profiles	1.0	2.05441
hsa-miR-340	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
hsa-miR-320b	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
ASNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29647
hsa-miR-4256	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
H3K27me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5325
SNU685	CCLE Cell Line Gene Expression Profiles	-1.0	-2.25486
Fundus albipunctatus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989723
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051772
interanterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05156
ZSCAN20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65085
hsa-miR-4755-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02825
H3K9me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29307
RIF1_KD_GDS4943_13_mouse_J1 ESC	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
organic acid transport	GO Biological Process Annotations 2015	1.0	null
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18859
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.01082
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
photophobia	HPO Gene-Disease Associations	1.0	null
MED12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49293
SEC61G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31311
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13511
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974958
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BICR22	COSMIC Cell Line Gene CNV Profiles	1.0	2.26395
regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
ventral nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11239
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06513
Visceral hump	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.15
GSE155031_5_v_1_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
INTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69022
hsa-miR-203	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-h-Classification_of_camel_SON_basal_genes_-_transporters_SON	Rummagene Transcription Factor Associations 2026	1.0	null
GAS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77188
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NCIH1734	CCLE Cell Line Gene CNV Profiles	1.0	2.15254
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.19718
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.25151
hsa-miR-3662	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
p2092	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.5