association dataset threshold value standardized value uterus BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -2.38176 decreased startle reflex MGI Mouse Phenotype Associations 2023 1.0 null ae3 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.221 tongueepidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.959223 G28T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.73806 r10 part of spinal vestibular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82138 OVCA 432 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17253 Septofimbrial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00594 HCT-116 COSMIC Cell Line Gene Mutation Profiles 1.0 null abnormality of the intestine GWASdb SNP-Phenotype Associations 1.0 0.762976 obstructive lung disease GWASdb SNP-Disease Associations 1.0 1.64992 CTCF_Caco-2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-geneSymbol_AR Rummagene Transcription Factor Associations 2026 1.0 null Entorhinal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16019 inner SZ in posterosuperior (dorsal) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.895578 CTCF_C2C12_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Transport of inorganic cations/anions and amino acids/oligopeptides Reactome Pathways 2024 1.0 null reproductive system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050977 OVISE CCLE Cell Line Gene CNV Profiles 1.0 1.78458 GSE217363_4_v_1_nlrp3_mouse RummaGEO Gene Perturbation Signatures 1.0 null Nephrolithiasis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.071 Anterior olfactory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23678 NPIPB4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60409 PDK1_knockout_265_GSE42187 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.40332 layer 1 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44158 CTCF_GM12864_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null colitis GWASdb SNP-Disease Associations 1.0 2.34245 SW1783 CCLE Cell Line Gene CNV Profiles -1.0 -1.43379 modulating GeneRIF Biological Term Annotations 1.0 null basolateral plasma membrane GO Cellular Component Annotations 2025 1.0 null PMC8481886-Table_1.xlsx-A_subsets-iMSC_fetal_MSC_UC_MSC_adipose_tissue_MSC_MSC Rummagene Transcription Factor Associations 2026 1.0 null HNF4A JASPAR Predicted Transcription Factor Targets 1.0 null Exocrine acinar cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.413 PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Hematopoietic cell TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.267 SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null DU-145 COSMIC Cell Line Gene Mutation Profiles 1.0 null asthma GWASdb SNP-Phenotype Associations 1.0 2.3201 plant-type vacuole COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.883 Central nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.533 terminal subparaventricular area of THyA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26653 Allergic Reaction DisGeNET Gene-Phenotype Associations 1.0 null EBF1-22473956-BONE-MARROW-MOUSE ChEA Transcription Factor Targets 2022 1.0 null BCR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.47916 SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null WM88 DepMap CRISPR Gene Dependency 1.0 2.23714 adenocarcinoma cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 GSE149903_3_v_2_myd88_mouse RummaGEO Gene Perturbation Signatures 1.0 null Xylem parenchyma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.153 RAD21_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE108500_1_v_0_foxp1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE173873_8_v_11_stra8_mouse RummaGEO Gene Perturbation Signatures -1.0 null BARHL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6258 BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.25678 GSE217694_3_v_2_pold1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Anterior olfactory nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06251 UBB_KO_GDS3906_492_mouse_Testis - 14 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7440-11A-01R-2187-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC6932815-ppat.1007634.s014.xlsx-ST4_DGE_ELF1-R8AvIFN6-mock_lfc2-external_gene_name_ELF1 Rummagene Transcription Factor Associations 2026 1.0 null Renal distal tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.91 CTCF_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCOR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null U-2 OS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.08762 T-47D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17253 Medullary collecting duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.793 PMC4070589-NIHMS573166-supplement-1.pdf-15-TP53_TP53 Rummagene Transcription Factor Associations 2026 1.0 null TCF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1534 GSE244233_1_v_0_quercetin_human RummaGEO Drug Perturbation Signatures -1.0 null Piriform-amygdalar area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11161 C2CD5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54406 MZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.03182 Perturb_6955_KO|KD_Titin|Rbm20_ERP122940 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.66896 Perturb_860_KO_Tsga8_SRP254760 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF MotifMap Predicted Transcription Factor Targets 1.0 null FOXM1-26456572-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Syndromic X-linked intellectual disability DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.045 H3K27me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PU1-27457419-CHIP-SEQ-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ESET_KO_GDS4508_348_mouse_Dorsal telencephalon from E14.5 embryos GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null hsa-miR-30a TargetScan Predicted Conserved microRNA Targets 1.0 0.193083 NFIC JASPAR Predicted Transcription Factor Targets 1.0 null Mineral metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.234 pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null ZCWPW1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36283 ERF::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0602 Endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.034 cation:cation antiporter activity GO Molecular Function Annotations 2015 1.0 null POU2F1-35413990-HUMAN-ARPOSCRPROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null AFTPH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.10443 H4C14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.28202 Celiac disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.946 Bed nuclei of the stria terminalis, anterior division, fusiform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04596 Renal proximal tubule cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.416 JHOS-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null NR3C1-21868756-MCF10A-HUMAN ChEA Transcription Factor Targets 2022 1.0 null LNCAP Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.829541 TBX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5302 layer VI of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.50707 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MI-06A-11R-A18U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_fibroblast of foreskin _hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.88468 epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053725 Xanthine dehydrogenase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.806 SETD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.58792 RAD21_MCF-7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null stratum pyramidale of caudal CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01357 CTCF_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Choroid plexus epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.728 HOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.0711 Nobox JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.4211 Temporal association areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51748 Ammonia CTD Gene-Chemical Interactions 1.0 null Crohn's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.315 hsa-miR-3121-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.127531 Perturb_795_KO_Tnfaip3_SRP332632 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -18.2596 DBP JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2165 hsa-miR-890 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 HMY1 DepMap CRISPR Gene Dependency 1.0 2.21918 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UN-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_cardiac fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ETV2::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0697 TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.468 PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-external_gene_name_ELF1 Rummagene Transcription Factor Associations 2026 1.0 null GSE227592_4_v_1_adar_human RummaGEO Gene Perturbation Signatures 1.0 null Primary somatosensory area, mouth, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19694 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6992-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KDM1A_KD_GDS5055_457_mouse_adipose tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null hsa-miR-30d TargetScan Predicted Conserved microRNA Targets 1.0 0.193083 sodium ion transmembrane transporter activity GO Molecular Function Annotations 2023 1.0 null PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.00236 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.52563 Crohn's disease GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.02218 outer portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.81899 SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Targets 2022 1.0 null disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.790827 DPF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03948 Stat5a::Stat5b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.9048 metal cation:proton antiporter activity GO Molecular Function Annotations 2025 1.0 null Gastric epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.661 VSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.4167 PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1 Rummagene Transcription Factor Associations 2026 1.0 null H3K9ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE185944_2_v_3_pth1r_mouse RummaGEO Gene Perturbation Signatures -1.0 null H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NAA30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39218 Ectorhinal area/Layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04823 Autosomal recessive disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.275 CTCF_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE171180,GSE171181_0_v_1_e7107_human RummaGEO Drug Perturbation Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7101-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SW156 DepMap CRISPR Gene Dependency 1.0 4.92571 Brain Lower Grade Glioma_LGG_TCGA-HW-7490-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chronic colitis GWASdb SNP-Phenotype Associations 1.0 1.92507 HUH-7 COSMIC Cell Line Gene Mutation Profiles 1.0 null duodenum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.308974 sodium ion import across plasma membrane GO Biological Process Annotations 2023 1.0 null Pancreatic juice TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.08 GSE207978_1_v_0_rai1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE135514_2_v_0_dasatinib_human RummaGEO Drug Perturbation Signatures 1.0 null abnormal stomach glandular epithelium morphology MGI Mouse Phenotype Associations 2023 1.0 null RAD21_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.270913 hsa-miR-135a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 transepithelial ammonium transport GO Biological Process Annotations 2025 1.0 null EMX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.27 CTCF_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null viscus TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BCL6B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.0055 Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JW-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7051-11A-02R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SLC29A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92973 CTCF_choroid plexus epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EN2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.9578 NCI-H2066 COSMIC Cell Line Gene Mutation Profiles 1.0 null Field CA1, stratum pyramidale Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26262 pallidal septum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22157 CTCF_NB4_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2861-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of LAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44905 VZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16117 496100345_FWM_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.00387 Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Hydathode TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.557 increased circulating cholesterol level IMPC Knockout Mouse Phenotypes 1.0 null microvillus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.517756 RH-41 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE175787_13_v_0_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3443-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAD21_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null antiporter activity GO Molecular Function Annotations 2015 1.0 null SUM 149PT Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.847845 CTCF_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lung disease GWASdb SNP-Disease Associations 1.0 0.906106 MSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.8668 UT7 CCLE Cell Line Gene CNV Profiles 1.0 1.4686 WRNIP1 ENCODE Transcription Factor Targets 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41S-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYLIP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78605 ATG9B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60037 outer SZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18209 gastric epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.724041 AXIN2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64663 multicellular organismal process GO Biological Process Annotations 2015 1.0 null HCC2218 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.886472 HOXB3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.2835 HDLM-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_HCT116_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null IGROV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormal chief cell morphology MPO Gene-Phenotype Associations 1.0 null Acquired metabolic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.525 exchanger GeneRIF Biological Term Annotations 1.0 null 496100647_TCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.02586 STAT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67922 CTCF_A549_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null FLI1-27457419-CHIP-SEQ-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ZBTB18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.8616 CTCF_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null proton transport GO Biological Process Annotations 2015 1.0 null Entorhinal area, lateral part, layer 2a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.24808 hsa-miR-448 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 GSE100316_0_v_6_mtor_mouse RummaGEO Gene Perturbation Signatures 1.0 null TMTC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68082 Entorhinal area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59395 membrane region GO Cellular Component Annotations 2015 1.0 null CTCF_brain microvascular endothelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_GM12801_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AU565 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.802627 layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.47792 Subparaventricular zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49842 Salivary duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.564 UBC Pathway Commons Protein-Protein Interactions 1.0 null layer 3 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16407 mantle zone of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31064 GSE127790_10_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null 496100395_TCx_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.15956 central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060324 Organum vasculosum laminae terminalis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.486 molecular_function GO Molecular Function Annotations 2015 1.0 null Estimated glomerular filtration rate GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.7 central nervous system disease GWASdb SNP-Disease Associations 1.0 0.104052 Perturb_6362_KO_Rrm2b_ERP134614 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.63762 Parotid acinar cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.546 Autoimmune disease of gastrointestinal tract DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.467 Hmx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.3021 POU3F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.8685 TBXT JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.68 PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5 Rummagene Transcription Factor Associations 2026 1.0 null HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0215 PSS008 DepMap CRISPR Gene Dependency 1.0 10.871 MOR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.847845 COLO-783 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_astrocyte of the spinal cord_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null decreased bone mineral content IMPC Knockout Mouse Phenotypes 1.0 null hsa-miR-664 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 CTCF_A549_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE210101,GSE210114_1_v_3_urod_human RummaGEO Gene Perturbation Signatures 1.0 null decreased prepulse inhibition IMPC Knockout Mouse Phenotypes 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A905-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Supraoptic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.568 496100306_FWM_no dementia_no TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.03897 gastric necrosis MGI Mouse Phenotype Associations 2023 1.0 null RAD21_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX2-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_15539_Mut_Ezh2_SRP220248 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.55819 CAMK2B Pathway Commons Protein-Protein Interactions 1.0 null blastula TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.227445 immune system phenotype MPO Gene-Phenotype Associations 1.0 null Perturb_5673_KO_Rbfox1/Rbfox2_SRP151185 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.5736 GSE213219_2_v_3_st3gal3_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCI-H2122 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.846918 496100316_TCx_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.41987 GSE162276_5_v_3_pparg_mouse RummaGEO Gene Perturbation Signatures -1.0 null NR4A2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.6766 lymphoid tissue TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 superficial stratum of CA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14933 RL DepMap CRISPR Gene Dependency 1.0 2.14873 GSE202434,GSE202438_12_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-7284-01B-11R-2241-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_3417_KO_Cdx2_SRP093647 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null biological regulation GO Biological Process Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-7006-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormal digestive secretion MPO Gene-Phenotype Associations 1.0 null reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null hsa-miR-3140-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 HOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9877 Kidney disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.131 HMG20A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64166 alimentary canal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null NKX2-5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4129 CTCF_fibroblast of villous mesenchyme_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anteroventral nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.54485 G130 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11412 ulcerative colitis GWASdb SNP-Phenotype Associations 1.0 2.3201 GSE113385_0_v_1_six1_mouse RummaGEO Gene Perturbation Signatures -1.0 null BBIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.83871 Alimentary canal TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 layer 4 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2356 Lung adenocarcinoma_LUAD_TCGA-69-8453-01A-12R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17508 kidney_a HPA Tissue Sample Gene Expression Profiles 1.0 1.12764 female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null SLU7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10788 Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-27a TargetScan Predicted Conserved microRNA Targets 1.0 0.136254 GSE244072_4_v_6_tfeb_mouse RummaGEO Gene Perturbation Signatures -1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-7644-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBL1XR1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Forebrain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.0 MDA-MB-231 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11412 Endometriosis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.345 Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Autoimmune disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.3 Entorhinal area, lateral part, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56872 CTCF_CH12.LX_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null basolateral plasma membrane GO Cellular Component Annotations 2015 1.0 null type 2 diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.569179 hsa-miR-27a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GSE149903_6_v_1_myd88_mouse RummaGEO Gene Perturbation Signatures 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-US-A77G-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Superior colliculus, zonal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.15991 GSE190322,GSE190324_3_v_4_rbm4_mouse RummaGEO Gene Perturbation Signatures -1.0 null intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05461 Stria vascularis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.63 LMX1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7911 Lateral visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67091 Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.14 viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.019956 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A5W4-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_GM12873_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXO1::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.9846 HCC4011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.49546 Viscus TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5ED-11A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GATA1_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null nhe2 GeneRIF Biological Term Annotations 1.0 null LP1 CCLE Cell Line Gene CNV Profiles -1.0 -1.61642 CTCF_GM12873_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null digestive/alimentary phenotype MPO Gene-Phenotype Associations 1.0 null Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.531 H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null limitans nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.52902 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Wernicke-Korsakoff syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.078 lateral subdivision of BNST Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04747 Orbital area, lateral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23815 CTCF_astrocyte of the cerebellum_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZR75B Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.706998 HCC1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -3.25078 GSE125219,GSE125221_5_v_8_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null Renal tubular transport disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.294 E2F4 ENCODE Transcription Factor Targets 1.0 null Lung adenocarcinoma_LUAD_TCGA-78-7154-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nhe4 GeneRIF Biological Term Annotations 1.0 null PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_36_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null kidney_c HPA Tissue Sample Gene Expression Profiles 1.0 1.24787 Renal medulla cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.405 Diarrhea DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.38 Brain Neoplasms HuGE Navigator Gene-Phenotype Associations 1.0 null lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.99648 transport GO Biological Process Annotations 2015 1.0 null Mesophyll cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.788 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5986-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMC3-22415368-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE205729,GSE205731_2_v_3_tazemetostat_human RummaGEO Drug Perturbation Signatures 1.0 null Esophageal epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.662 CTCF_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-374a TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 Cell body membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.616 NCI-H847 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null STAT3 ChEA Transcription Factor Targets 1.0 null forebrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.073349 epithalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.571219 CTCF_WERI-Rb-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CMC4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.07435 496100514_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.04047 GSE139987_1_v_2_rosiglitazone_mouse RummaGEO Drug Perturbation Signatures 1.0 null CTCF_MEL cell line_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.946 Prdm5 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 33.4338 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.022255 Hematopoietic system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.267 MEOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7371 CUX1 ENCODE Transcription Factor Targets 1.0 null hsa-miR-1279 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 NCIH522 DepMap CRISPR Gene Dependency 1.0 2.35699 transporter activity GO Molecular Function Annotations 2015 1.0 null CTCF_GM12868_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DAN-G Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27174 Acute Myeloid Leukemia_LAML_TCGA-AB-2992-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.06 CTCF_SK-N-SH_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12874_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Modiolus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.75 lateral hemisphere of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.890535 HOXA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.4403 GSE135350_3_v_7_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null layer 2 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06756 abnormal immune system physiology MPO Gene-Phenotype Associations 1.0 null superficial stratum of THyB-D Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21046 abnormal gastric gland morphology MPO Gene-Phenotype Associations 1.0 null diabetes mellitus GWASdb SNP-Phenotype Associations 1.0 0.26742 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.957922 Extraglomerular mesangial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.688 Mean corpuscular hemoglobin concentration GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.2301 periventricular stratum of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33577 GSE130383_1_v_3_gps2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ae1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.648 MZ in dorsomedial parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00783 GSE205540_2_v_3_phloridzin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Basolateral plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.593 hypersensitivity reaction disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.790827 GSE116354,GSE117379_2_v_4_cox2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Essential hypertension DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.015 CTCF-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CIITA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85308 HOXA5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.8765 L3MBTL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78113 NCI-H889 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11412 Pancreatic acinar cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.227 EP300 ChEA Transcription Factor Targets 1.0 null LRCH4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26642 Lymphocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.267 abnormality of the cardiovascular system GWASdb SNP-Phenotype Associations 1.0 0.211939 inorganic cation import across plasma membrane GO Biological Process Annotations 2025 1.0 null HCC-366 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-4760-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.111118 NCI-H727 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.85147 POU3F4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6113 PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-ensembl_gene_id_ELF1 Rummagene Transcription Factor Associations 2026 1.0 null Nucleus of the brachium of the inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04382 GSE131161_1_v_0_rarres1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Field CA2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34066 OVK-18 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-30b TargetScan Predicted Conserved microRNA Targets 1.0 0.165047 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null abnormality of immune system physiology GWASdb SNP-Phenotype Associations 1.0 0.369918 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KP4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18618 hsa-miR-4687-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.5171 CTCF_K562_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE234340_3_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_foreskin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormal joint morphology GWASdb SNP-Phenotype Associations 1.0 0.526408 E2F5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.24337 CTCF_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT3 ENCODE Transcription Factor Targets 1.0 null kidney_d HPA Tissue Sample Gene Expression Profiles 1.0 1.0569 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5453-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-3662 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 ae2 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.381 Juxtaglomerular apparatus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.572 mantle zone of CA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14933 abnormal digestive system morphology MPO Gene-Phenotype Associations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-5491-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CD63 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.49011 DLX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2758 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AC-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null monoatomic cation transmembrane transport GO Biological Process Annotations 2023 1.0 null M059K Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18228 HDAC2_Deficiency_GDS2624_658_mouse_Embryonic heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null CTCF_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14312 DIPK1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9295 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H650 COSMIC Cell Line Gene Mutation Profiles 1.0 null KYSE-70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05657 epithelioma cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null brain disease GWASdb SNP-Disease Associations 1.0 0.162412 ERG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.23452 Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.15535 Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QH-01A-11R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE131377_1_v_0_spocd1_mouse RummaGEO Gene Perturbation Signatures 1.0 null POU4F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.7669 496100360_FWM_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.14695 Immune system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.267 musculoskeletal system disease GWASdb SNP-Disease Associations 1.0 0.352374 P2URK562 DepMap CRISPR Gene Dependency 1.0 3.1804 GSE158715_3_v_0_cyp1b1_mouse RummaGEO Gene Perturbation Signatures 1.0 null RAD21_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMAD3-21741376-EPCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CTCF_fibroblast of pedal digit skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateropallial amygdalopiriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44995 Pancreatic adenocarcinoma_PAAD_TCGA-F2-6879-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NCI-H2291 COSMIC Cell Line Gene Mutation Profiles 1.0 null sodium:proton antiporter activity GO Molecular Function Annotations 2025 1.0 null DUSP23 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41647 Lingula (I) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17814 Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQA-01A-21R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LMNA_Lmna Gly609Gly knock-in_GDS4490_615_mouse_Liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null CTCF_mammary epithelial cell_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_endothelial cell of umbilical vein_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null nucleus of the stria terminalis, medial division, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45229 MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5158 r4 part of medial paralemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3022 mammillary part of THyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14111 ZNF143 ENCODE Transcription Factor Targets 1.0 null superficial stratum of PO2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1049 Allergic disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.708 abnormal stomach mucosa morphology MGI Mouse Phenotype Associations 2023 1.0 null WT1-25993318-PODOCYTE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_15726_KO_Il1rl1_SRP274117 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.36077 BT549 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.3437 Intestinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.306 GSE87617_1_v_0_ascl1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE100316_5_v_6_mtor_mouse RummaGEO Gene Perturbation Signatures 1.0 null TRPS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.5908 hsa-miR-4463 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 EMX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.4694 Field CA3, stratum pyramidale Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40218 YY1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMC3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JJN-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17253 autoimmune disease of gastrointestinal tract GWASdb SNP-Disease Associations 1.0 0.614068 H3K27me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.52072 KLF4-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null shell of SCH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45929 hsa-miR-4797-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.091223 sodium:proton antiporter activity GO Molecular Function Annotations 2023 1.0 null GSE198826,GSE198911_1_v_2_dexamethasone_mouse RummaGEO Drug Perturbation Signatures 1.0 null CTCF_GM19238_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1838 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.49546 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054116 Subiculum, ventral part, stratum radiatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2783 Subapical complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.016 CTCF_GM12865_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null E2F1-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SK-MEL-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null Apical complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.235 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5455-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Metabolic Acidosis DisGeNET Gene-Phenotype Associations 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0215 Sodium/Proton exchangers Reactome Pathways 2014 1.0 null HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LGE-VZ border region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01159 increased circulating cholesterol level MGI Mouse Phenotype Associations 2023 1.0 null SUP-T1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A76R-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ARGFX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5009 SUPT6H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.68747 769-P COSMIC Cell Line Gene Mutation Profiles 1.0 null Secretory granule membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.802 Germinal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.109 CTCF_epithelial cell of esophagus_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null spectrum GeneRIF Biological Term Annotations 1.0 null H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null superficial stratum of TSPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46023 CTCF_cardiac muscle cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null White blood cell types GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.51549 Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_GM06990_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Other source TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.8 NCI-H1623 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11412 H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU4F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6443 CCDC9B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.95649 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null monoatomic ion transport GO Biological Process Annotations 2025 1.0 null PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null Sox6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.9598 potassium ion transmembrane transport GO Biological Process Annotations 2023 1.0 null ulcerative colitis GWASdb SNP-Disease Associations 1.0 2.34245 POU2F1::SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 57.1191 ECGI10 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 all GWASdb SNP-Phenotype Associations 1.0 0.151619 lymphoid cell TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 ZNF410 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.849 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.40971 skin TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null LHFPL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12934 PMC11716045-peerj-13-18816-s007.xlsx-Sheet1-KLF9_KLF9 Rummagene Transcription Factor Associations 2026 1.0 null Christianson syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.608 CTCF-21964334-BJAB-B-HUMAN ChEA Transcription Factor Targets 2022 1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null GSE192771_2_v_0_sorafenib_human RummaGEO Drug Perturbation Signatures -1.0 null LS-180 COSMIC Cell Line Gene Mutation Profiles 1.0 null PROKR2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.72705 Carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.107 GSE148695,GSE167281_0_v_1_satb2_mouse RummaGEO Gene Perturbation Signatures 1.0 null osteoclasts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.921085 Obstructive Azoospermia DisGeNET Gene-Disease Associations 1.0 null Foxf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.9242 r5 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.17796 NR3C1 JASPAR Predicted Transcription Factor Targets 1.0 null Central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.143 abnormal stomach glandular epithelium morphology MPO Gene-Phenotype Associations 1.0 null CTCF_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GLC82 CCLE Cell Line Gene CNV Profiles 1.0 1.36793 SUM149PT DepMap CRISPR Gene Dependency 1.0 4.36725 GSE162892_3_v_0_isox_human RummaGEO Drug Perturbation Signatures 1.0 null CTCF_cardiac muscle cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12875_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Metabolic acidosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.982 Bronchial disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.042 acid secretion GO Biological Process Annotations 2015 1.0 null GBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4892 parabigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10158 lateral portion of the shell Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.895077 MSTO211H DepMap CRISPR Gene Dependency 1.0 4.33401 Renal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.73 EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SRRM3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.95326 SG in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.44446 ATPase inhibitor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.827 CTCF_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null urogenital system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.050649 CTCF_fibroblast of lung_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null cation transport GO Biological Process Annotations 2015 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A9DE-11A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A-375 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11412 H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of carbohydrate metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.174187 Gastrointestinal tract TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 BARHL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.4456 Colitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.105 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040239 Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.265 Inherited metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.094 central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.92815 ITSN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53646 endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 Lung squamous cell carcinoma_LUSC_TCGA-98-A53I-01A-31R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.344 Investment cone COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.916 SG in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.39849 CTCF_GM12867_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Na+/H+ exchanger InterPro Predicted Protein Domain Annotations 1.0 null RAD21_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE246195,GSE246305_1_v_3_sin3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null CTCF_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RBPJ-21746931-IB4-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Parasubthalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36127 lateral hypothalamic area, anterior part Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.85118 GSE119498_0_v_10_setd5_mouse RummaGEO Gene Perturbation Signatures 1.0 null Primary immunodeficiency disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.282 anterior nucleus of pulvinar Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17187 CTCF_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-7 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 hsa-miR-4667-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 sodium:proton antiporter activity GO Molecular Function Annotations 2015 1.0 null KYSE270 CCLE Cell Line Gene CNV Profiles -1.0 -1.39882 ELK4 JASPAR Predicted Transcription Factor Targets 1.0 null PMC4823830-ncomms11171-s3.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3 Rummagene Transcription Factor Associations 2026 1.0 null H2AB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.14457 single-organism cellular process GO Biological Process Annotations 2015 1.0 null DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2847 superficial stratum of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05534 MDAMB231 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.26071 Intracellular canaliculus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.624 Hmx2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.4457 POLR2A_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE180951_2_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures 1.0 null HOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.6774 KYSE-520 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05657 decreased startle reflex IMPC Knockout Mouse Phenotypes 1.0 null NEUROD6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.01735 Kidney Chromophobe_KICH_TCGA-KN-8437-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Entorhinal area, medial part, ventral zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22223 hsa-miR-1243 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 hsa-miR-4717-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Perturb_3415_KO_Cdx2_SRP093647 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6021-01A-11R-1686-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NANOG-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE154767_4_v_0_adam10_mouse RummaGEO Gene Perturbation Signatures 1.0 null HOXB2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.132 Renal proximal tubule epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.817 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nrf2_deficiency_GDS3406_156_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null PMC11297914-41389_2024_531_MOESM1_ESM.pdf-290-MLXIP_MLXIP Rummagene Transcription Factor Associations 2026 1.0 null Anterolateral visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55375 functional abnormality of the gastrointestinal tract GWASdb SNP-Phenotype Associations 1.0 0.925423 diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.291541 vascular disease GWASdb SNP-Disease Associations 1.0 0.09843 Gastric epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.622 Peroxisomal importomer complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.632 HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.72013 POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE212330_1_v_3_azacitidine_human RummaGEO Drug Perturbation Signatures 1.0 null monoatomic cation transmembrane transport GO Biological Process Annotations 2025 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5549-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoid tissue TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.267 contain GeneRIF Biological Term Annotations 1.0 null anteromedial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01574 SH2D3A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25159 PF-382 COSMIC Cell Line Gene Mutation Profiles 1.0 null TE-4 COSMIC Cell Line Gene Mutation Profiles 1.0 null Serous acinar cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.039 CTCF_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null WSUNHL DepMap CRISPR Gene Dependency 1.0 2.78226 Prostate adenocarcinoma_PRAD_TCGA-TK-A8OK-01A-22R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC-19915707-AK7-human ChEA Transcription Factor Binding Site Profiles 1.0 null LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.846918 bone disease GWASdb SNP-Disease Associations 1.0 0.465227 EPLC272H DepMap CRISPR Gene Dependency 1.0 2.0848 Hybridoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.696 ELL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15238 RABEP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.98313 inorganic cation transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null RAD21_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE240645_1_v_0_u90926_mouse RummaGEO Gene Perturbation Signatures 1.0 null abnormality of the abdominal organs GWASdb SNP-Phenotype Associations 1.0 0.284902 CTCF_CH12.LX_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBX19 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.7351 parasubthalamic nucleus (migrated) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.65457 Lung squamous cell carcinoma_LUSC_TCGA-43-3394-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1739 rt4 HPA Cell Line Gene Expression Profiles 1.0 1.62049 transepithelial transport GO Biological Process Annotations 2025 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CAMK2G Pathway Commons Protein-Protein Interactions 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-3E-AAAZ-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GIMEN DepMap CRISPR Gene Dependency 1.0 2.53741 CTCF_A549_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null arthritis GWASdb SNP-Disease Associations 1.0 2.34245 Lef1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.5606 PRORP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84699 SMC3_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PAX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9005 solute:proton antiporter activity GO Molecular Function Annotations 2015 1.0 null GSE111061_1_v_0_tofacitinib_human RummaGEO Drug Perturbation Signatures 1.0 null LHX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5278 r2 part of principal trigeminal sensory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46413 EP300-21415370-HL-1-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE193351_1_v_2_ruxolitinib_human RummaGEO Drug Perturbation Signatures -1.0 null CEBPB-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_15612_KO_Net39_SRP273304 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.73776 SK-MEL-31 COSMIC Cell Line Gene Mutation Profiles 1.0 null lateral septal nucleus, intermediate part, periventricular Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18479 CEBPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0203 layer II of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05108 Lower respiratory tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.07 GBX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.22331 GSE199606_5_v_4_ricin_mouse RummaGEO Drug Perturbation Signatures -1.0 null 496100351_FWM_no dementia_TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.0511 Piriform area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11695 UBB_KO_GDS3906_491_mouse_Testis - 7 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ventromedial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04546 GSE217405_3_v_2_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_GM12875_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in primary auditory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02868 single-organism localization GO Biological Process Annotations 2015 1.0 null GSE145915_5_v_1_pcm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Micropyle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.738 abnormality of leukocytes GWASdb SNP-Phenotype Associations 1.0 0.882984 posterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.894011 CTCF_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormal gastric parietal cell morphology MPO Gene-Phenotype Associations 1.0 null NCI-H1048 COSMIC Cell Line Gene Mutation Profiles 1.0 null female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-6146-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null alimentary canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.07544 ESRRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.9742 PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Crohn's disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.85 CH157MN DepMap CRISPR Gene Dependency 1.0 2.16955 Initial collecting tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.903 periventricular stratum of the VAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54526 HOXA7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9287 CTCF_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Principal sensory nucleus of the trigeminal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00772 abnormality of the respiratory system GWASdb SNP-Phenotype Associations 1.0 0.382603 Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TGF-beta_OE_GDS2974_137_mouse_corneas GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null abnormal digestion MPO Gene-Phenotype Associations 1.0 null CTCF_epithelial cell of proximal tubule_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81T-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sperm plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.748 GSE216538_5_v_3_mrs2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ZMIZ1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZFX-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GATA5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1191 r1 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22711 NKX6-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.3546 Lung adenocarcinoma_LUAD_TCGA-05-4403-01A-01R-1206-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6984-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC6932815-ppat.1007634.s014.xlsx-ST4_DGE_ELF1-R8AvIFN6-mock_lfc2-ensembl_gene_id_ELF1 Rummagene Transcription Factor Associations 2026 1.0 null Nephrocalcinosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.319 ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 97.0489 HOXA10 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3473 Entorhinal area, medial part, ventral zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16148 BHLHE40 ENCODE Transcription Factor Targets 1.0 null H3K27me3_CD4 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null SPI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null POU2F2 JASPAR Predicted Transcription Factor Targets 1.0 null VAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1178 NKRF CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.93395 BFTC-909 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055896 r3 part of spinal trigeminal sensory column, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1976 Oxyntic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.177 Barrett's esophagus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.699 hsa-miR-27b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 EZH2-27294783-CHIP-SEQ-NPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null BHLHE40_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null M14 COSMIC Cell Line Gene Mutation Profiles 1.0 null PDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.9989 CTCF_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null A-CA-04-2009(H1N1)_Day1_22532695_GSE36328 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.42977 CBX2-22325352-293T-REX-HUMAN ChEA Transcription Factor Targets 2022 1.0 null abnormal digestive system physiology MPO Gene-Phenotype Associations 1.0 null CTCF_GM12874_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A6RY-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCOR1 ENCODE Transcription Factor Targets 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-01A-12R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10533402-41586_2023_6549_MOESM6_ESM.xlsx-Ion_channel_change-Supplementary_Table_2_Cell_type_differentially_expressed_ion_and_water_channel_genes_between_FOXI1-KO_to_WT_airway_epithelia_FOXI1 Rummagene Transcription Factor Associations 2026 1.0 null BT-20 COSMIC Cell Line Gene Mutation Profiles 1.0 null mantle zone of Mam Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14259 hematopoietic system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 CTCF_fibroblast of skin of abdomen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYC ChEA Transcription Factor Targets 1.0 null membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.139635 RAD21_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FOXO1::ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.6249 CTCF_K562_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPP25 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13955 GOTO COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_spleen_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100459_PCx_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 4.64508 cerebral cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056276 r3 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67861 membrane part GO Cellular Component Annotations 2015 1.0 null GSE154074_1_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Lingula (I), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23031 gastrointestinal inflammation GWASdb SNP-Phenotype Associations 1.0 1.3815 plant-type vacuole membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.812 NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.829541 CTCF_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Atypical Femoral Fracture DisGeNET Gene-Phenotype Associations 1.0 null JURKAT COSMIC Cell Line Gene Mutation Profiles 1.0 null decreased prepulse inhibition MGI Mouse Phenotype Associations 2023 1.0 null GSE145915_3_v_2_pcm1_mouse RummaGEO Gene Perturbation Signatures 1.0 null MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22823 NEIL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02442 KAP1-27257070-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null regulation of biological quality GO Biological Process Annotations 2015 1.0 null OVISE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27174 Field CA3, stratum oriens Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.42492 H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of skeletal morphology GWASdb SNP-Phenotype Associations 1.0 0.272375 SG in dysgranular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.0101 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null r7 part of the nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4315 dorsal endopiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.01657 Serum protein levels (sST2) GWAS Catalog SNP-Phenotype Associations 2025 1.0 3.25229 DMC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51666 HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.3212 ion homeostasis GO Biological Process Annotations 2015 1.0 null LLC-PK1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.853 KMS-26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.9125 cerebral hemisphere TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055278 C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.948019 ORC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.92685 abnormal stomach wall morphology MPO Gene-Phenotype Associations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_K562_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.137 HCC1395 CCLE Cell Line Gene CNV Profiles -1.0 -2.59447 GSE137818_5_v_1_brca2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GRIN2C Pathway Commons Protein-Protein Interactions 1.0 null CTCF_retinal pigment epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE237812,GSE237813_3_v_2_hmgb2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Atrophic gastritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.155 FKBP8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08249 paraterete nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.38974 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Glucose metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.119 SW1271 CCLE Cell Line Gene CNV Profiles -1.0 -2.3514 NCI-H2452 COSMIC Cell Line Gene Mutation Profiles 1.0 null MDAMB415 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.669364 Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-A59R-11A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DLX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2697 ZNF556 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.08784 Nucleomorph COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.558 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-11A-02R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_foreskin fibroblast_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4700-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 GSE149769_1_v_0_nlrp12_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE236502_1_v_3_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null CHP2 Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-125a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 CTCF_GM10248_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SP-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null intermediate stratum of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82407 Lung squamous cell carcinoma_LUSC_TCGA-34-8456-01A-21R-2326-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Spinal cord TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.533 Autoimmune disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.946 Orbital area, lateral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61104 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XP-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.904673 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B1-01A-12R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EN1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.064 abnormal respiratory system morphology GWASdb SNP-Phenotype Associations 1.0 0.411606 Syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.124 Liver TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 3.067 Supplemental somatosensory area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52751 CTCF_keratinocyte_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer 1 of ERCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15698 GSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.7327 RAD21_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE238116_3_v_2_egr1_human RummaGEO Gene Perturbation Signatures 1.0 null ZNF217-24962896-MCF7-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null HK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.26619 hypersensitivity reaction type ii disease GWASdb SNP-Disease Associations 1.0 0.128885 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27578 Runx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.2695 PTOV1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.82067 dorsomedial part of VMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18194 Lung squamous cell carcinoma_LUSC_TCGA-37-A5EN-01A-21R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null macrophage BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.04859 crohn's disease GWASdb SNP-Disease Associations 1.0 0.614068 nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057484 LMX1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.332 Adrenocortical carcinoma_ACC_TCGA-OR-A5J7-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE174406_2_v_1_lin28b_mouse RummaGEO Gene Perturbation Signatures -1.0 null localization GO Biological Process Annotations 2015 1.0 null SOX9-26525672-CHIP-SEQ-LIMBBUDS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null immune system disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.790827 NKX6-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.3777 epithelium TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE119498_2_v_4_setd5_mouse RummaGEO Gene Perturbation Signatures -1.0 null immune system disease GWASdb SNP-Disease Associations 1.0 0.179883 decreased bone mineral density MGI Mouse Phenotype Associations 2023 1.0 null GSE133555_0_v_1_npm1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Gastric acid secretion KEGG Pathways 2026 1.0 null potassium ion transport GO Biological Process Annotations 2025 1.0 null lateral mammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34721 medial tuberal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39248 RAD21_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null P300-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SNU-398 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.73302 GRIN1 Pathway Commons Protein-Protein Interactions 1.0 null Bhlha15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 29.4661 substrate-specific transporter activity GO Molecular Function Annotations 2015 1.0 null monoatomic ion transport GO Biological Process Annotations 2023 1.0 null HOXB7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.678 Perturb_58_KO_Gadd45a/Gadd45b_SRP187210 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.47439 RAD21_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE114232_8_v_11_mavs_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.468 Telencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.0 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCIAML3 DepMap CRISPR Gene Dependency 1.0 3.32841 Tbx6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.4255 GSE119498_0_v_7_setd5_mouse RummaGEO Gene Perturbation Signatures 1.0 null Egg chorion COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.704 roof plate of p2 (epithalamic roofplate) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.11769 EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.9873 CTCF_MCF-7_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Serum protein levels (sST2) GWAS Catalog SNP-Phenotype Associations 1.0 1.32451 ChIP_K27me3_17603471_mouseMEF ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Basophil count GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.1301 Arcuate hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33716 PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1 Rummagene Transcription Factor Associations 2026 1.0 null transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null Autoimmune disease of gastrointestinal tract DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.946 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4680-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 subparafascicular nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24091 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71D-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE143955_1_v_0_ripk1_mouse RummaGEO Gene Perturbation Signatures 1.0 null ATN-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Stomach disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.117 LN-18 COSMIC Cell Line Gene Mutation Profiles 1.0 null CAL-85-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.847845 Caco-2/BBe cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.497 Orbital area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.1366 CTCF_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE63048_11_v_12_morc1_mouse RummaGEO Gene Perturbation Signatures 1.0 null disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039499 H3K27me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null isoforms GeneRIF Biological Term Annotations 1.0 null MAFA MotifMap Predicted Transcription Factor Targets 1.0 null CTCF_mammary epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE74251_2_v_1_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null PMC8104016-hcg-12-e002353-s010.xlsx-mTHP1-LPS_30kb-Nearest_reported_Gene_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Primary somatosensory area, unassigned, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02034 GSE193351_1_v_0_ruxolitinib_human RummaGEO Drug Perturbation Signatures -1.0 null CTCF_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5883-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Inflammatory bowel disease GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.0301 stomach BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 cation transmembrane transport GO Biological Process Annotations 2015 1.0 null Kidney Chromophobe_KICH_TCGA-KO-8415-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6L9-06A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null acquired metabolic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.085205 hsa-miR-1206 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Gata3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 28.4515 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RMG-I Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.23108 GSE216043_10_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A705-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_16720_Mut_Lmna_SRP309326 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.484 hsa-miR-3607-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.226173 RAD21 ENCODE Transcription Factor Targets 1.0 null caudal ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22434 Delirium GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.8 FBH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.97218 GSE125403_7_v_0_venetoclax_human RummaGEO Drug Perturbation Signatures -1.0 null small intestine HPA Tissue Protein Expression Profiles 1.0 1.46028 Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.4675 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.22898 NCIH2106 CCLE Cell Line Gene CNV Profiles -1.0 -1.5865 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nodulus (X) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45744 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_MCF-7_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null NEFL Pathway Commons Protein-Protein Interactions 1.0 null plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null BB30HNC DepMap CRISPR Gene Dependency 1.0 3.68262 Serous cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.866 NCIH69 CCLE Cell Line Gene CNV Profiles -1.0 -1.49532 stomach GTEx Tissue Gene Expression Profiles 1.0 1.92758 Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NH-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brush border membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.821 Chloride channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.074 PRKCZ_KO_GDS4310_293_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Renal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.493 CEBPD JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2993 MRK-NU-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A3LQ-01A-21R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DETROIT562 CCLE Cell Line Gene CNV Profiles 1.0 1.99238 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 r1 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.1115 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null entorhinal cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30905 Sox3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.8134 RAD21_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of gingiva_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Autosomal recessive spinocerebellar ataxia 19 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.224 Renal medulla TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.559 BHLHE40_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null telencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054575 NTERA-2_CL_D1 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE211286_1_v_3_tcf12_mouse RummaGEO Gene Perturbation Signatures 1.0 null respiratory system disease GWASdb SNP-Disease Associations 1.0 0.730753 Casparian strip COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.923 stomach_3a HPA Tissue Sample Gene Expression Profiles 1.0 1.69933 CRX-20693478-RETINA-MOUSE ChEA Transcription Factor Targets 2022 1.0 null ESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.3498 SCO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6773 NFATC3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5845 GSE149903_4_v_2_myd88_mouse RummaGEO Gene Perturbation Signatures 1.0 null CBX2 ENCODE Transcription Factor Targets 1.0 null Anterior olfactory nucleus, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57186 trunk TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CTCF_GM19240_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Recycling endosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.372 PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_ID_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null mammillary area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14211 lateral tuberal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.95458 Medullary collecting duct cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.84 Lateral amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.22234 r11 part of the trigeminal column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.72443 HCC1569 CCLE Cell Line Gene CNV Profiles 1.0 1.97586 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null GSE147959,GSE147960_5_v_3_stat1_mouse RummaGEO Gene Perturbation Signatures 1.0 null POU5F1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6078 hematopoietic system disease GWASdb SNP-Disease Associations 1.0 1.00407 Tracheal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.92 Submucosal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.595 superficial stratum of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.38974 MEOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7311 CTCF_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-7888-01A-11R-2156-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null potassium ion transport GO Biological Process Annotations 2023 1.0 null c-Myc_OE_GDS3321_157_mouse_lung adenocarcinomas alveolar epithelia GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-6846-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RKO COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1734 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE135686_2_v_3_etomoxir_human RummaGEO Drug Perturbation Signatures -1.0 null Atopic dermatitis GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.02218 STAT3-18555785-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Piriform area, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18157 CTCF_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_13572_KD_Setdb1_SRP059699 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -6.19743 DMS-53 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Small_Intestine-duodenum glandular cell Tabula Sapiens Gene-Cell Associations 1.0 0.716972 abnormality of the large intestine GWASdb SNP-Phenotype Associations 1.0 1.19254 GSE199606_6_v_4_ricin_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR Rummagene Transcription Factor Associations 2026 1.0 null ES-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null POU4F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.794 GRIN2B Pathway Commons Protein-Protein Interactions 1.0 null NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION ChEA Transcription Factor Targets 2022 1.0 null HS 766T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.847845 hsa-miR-135b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 HNF1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.983 ChIP_CTCF_18555785 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null ZNF17 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.98484 Lung adenocarcinoma_LUAD_TCGA-05-4433-01A-22R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BSX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9562 autoimmune disease of gastrointestinal tract DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.790827 cation transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.937982 Entorhinal area, lateral part, layer 2b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.06476 Acute Myeloid Leukemia_LAML_TCGA-AB-2837-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-11A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null YY1 MotifMap Predicted Transcription Factor Targets 1.0 null Diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.104 GSE86507,GSE86509_0_v_1_hoxb7_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE216147_0_v_3_rbm20_mouse RummaGEO Gene Perturbation Signatures -1.0 null KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.94599 POU1F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2561 OE21 COSMIC Cell Line Gene Mutation Profiles 1.0 null NCCIT COSMIC Cell Line Gene Mutation Profiles 1.0 null Ciliated epithelial cell_Esophagus_Human CellMarker Gene-Cell Type Associations 1.0 null Field CA3, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12839 solute:cation antiporter activity GO Molecular Function Annotations 2015 1.0 null digestive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 U87MG DepMap CRISPR Gene Dependency 1.0 3.9691 Mpp10 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.034 ESRRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.0656 over GeneRIF Biological Term Annotations 1.0 null Retina TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.333 anatomical structure development GO Biological Process Annotations 2015 1.0 null organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058388 hypersensitivity reaction type ii disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.790827 secondary active transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null GSE60837_0_v_3_bcl9_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR Rummagene Transcription Factor Associations 2026 1.0 null Perturb_14225_KO_Tcf12_SRP392331 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.97738 inorganic cation transmembrane transport GO Biological Process Annotations 2025 1.0 null C11orf68 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.943 CTCF_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM13976_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_GM12864_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null bed nucleus of the stria terminalis, medioseptal division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33624 CTCF_fibroblast of upper leg skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Periventricular zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3833 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.702 AR4-2J cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.654 HT55 COSMIC Cell Line Gene Mutation Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2975-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NR1H2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.36 superficial stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06697 Body Height DisGeNET Gene-Phenotype Associations 1.0 null Stat4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.5942 FXR MotifMap Predicted Transcription Factor Targets 1.0 null CTCF_H1-hESC_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-370 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 Abomasum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.896 GSE102269_1_v_2_clpp_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE174406_2_v_0_lin28b_mouse RummaGEO Gene Perturbation Signatures -1.0 null mammarygland.lact. BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 CTCF_GM19239_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12867_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_8514_KO_Setd1b_SRP328849 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 JHUEM7 DepMap CRISPR Gene Dependency 1.0 7.22214 Gastric epithelium cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.819 496100653_PCx_probable Alzheimer's disease_no TBI_82_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.59967 Perturb_15286_KO_Trp73_SRP067006 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 8.30759 H3K27me3_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null prion disease GWASdb SNP-Disease Associations 1.0 0.730983 IMCD cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.416 CTCF_fibroblast of foreskin _hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null layer 3 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63563 abnormal mucous neck cell morphology MPO Gene-Phenotype Associations 1.0 null CTCF_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null immunologic hypersensitivity GWASdb SNP-Phenotype Associations 1.0 1.29363 BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.6303 CLEC11A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86553 periventricular nucleus, preoptic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.40175 KLM1 CCLE Cell Line Gene CNV Profiles 1.0 1.59624 Lung squamous cell carcinoma_LUSC_TCGA-77-7139-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of THyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74828 Endopiriform nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04823 Merocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.58 LHX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4959 RAD21_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT5A-24692510-EPITHELIUM-MOUSE-MAMMARY ChEA Transcription Factor Targets 2022 1.0 null Female reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.967 asthma GWASdb SNP-Disease Associations 1.0 2.34245 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-4733-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14537 Primary somatosensory area, barrel field, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.43777 SMAD4 ChEA Transcription Factor Targets 1.0 null Frontal lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.0 brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060593 Ammonium transmembrane transporter complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.112 DB COSMIC Cell Line Gene Mutation Profiles 1.0 null Esophageal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.003 CTCF_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null regulation of ph GO Biological Process Annotations 2015 1.0 null Cerebral cortex TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.0 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5465-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE216147_2_v_3_rbm20_mouse RummaGEO Gene Perturbation Signatures -1.0 null RAD21_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ISX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1291 Basal part of cell COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 snoutepidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.46904 Kna TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.088 CTCF_MEL cell line_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null TE-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JEG-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_MCF-7_hg19_9 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lateral septal nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33671 Renal tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.026 EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23156 Brain Lower Grade Glioma_LGG_TCGA-P5-A736-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RAD21-21589869-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null chp3 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.085 sodium:potassium-exchanging ATPase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.739 MDAMB361 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.22039 GSE137818_2_v_6_brca2_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF652 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6463 Perturb_17338_KO_Mageb4_SRP259999 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MV-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell part LOCATE Predicted Protein Localization Annotations 1.0 null RAD21_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null colon GeneRIF Biological Term Annotations 1.0 null GSE234637_3_v_0_cytarabine_human RummaGEO Drug Perturbation Signatures 1.0 null CTCF_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Esophageal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.962 CTCF_fibroblast of mammary gland_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null increased inflammatory response MPO Gene-Phenotype Associations 1.0 null Intercalated disc COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.003 CTCF_fibroblast of lung_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-596 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Gastric gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.14 CTCF_retinal pigment epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05108 GSE188870,GSE188871_0_v_2_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null IZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.34435 PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHOM1 CCLE Cell Line Gene CNV Profiles -1.0 -1.53392 GATA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.6733 Lung adenocarcinoma_LUAD_TCGA-97-7552-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_BE2C_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Renal proximal tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.926 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.49272 CTCF_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hypochlorhydria MGI Mouse Phenotype Associations 2023 1.0 null Lymphoid cell TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.267 NCIH2110 DepMap CRISPR Gene Dependency 1.0 2.24243 stomach inflammation MPO Gene-Phenotype Associations 1.0 null B-lymphocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.267 PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2 Rummagene Transcription Factor Associations 2026 1.0 null G-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC1171 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13578 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-VB-A8QN-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null T-84 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.618 H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null interpositus (intermediate) nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.923095 NCCLMS1C1 DepMap CRISPR Gene Dependency 1.0 4.62412 Piriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06423 CTCF_GM10266_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null sodium ion transmembrane transport GO Biological Process Annotations 2025 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PRRX2 JASPAR Predicted Transcription Factor Targets 1.0 null oocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.280717 EVSAT CCLE Cell Line Gene CNV Profiles -1.0 -1.3574 SMC3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null plasma membrane part GO Cellular Component Annotations 2015 1.0 null Basal part of cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.522 Urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.163 Sperm individualization complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.74 superficial stratum of r3BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.68 Anterolateral visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53164 CTCF_GM12866_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE161184_0_v_1_tlr7_mouse RummaGEO Gene Perturbation Signatures -1.0 null dorsalstriatum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07371 HT144SKINFV1 DepMap CRISPR Gene Dependency 1.0 3.35035 GSE188870,GSE188871_1_v_2_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null mantle zone of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02236 frontal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.280364 PMC12956708-DataSheet1.xlsx-Supplementary_Table_7-Supplementary_Table_6_The_DEGs_from_high_altitude_between_AMS_and_non-eAMS_group_of_GSE75665_TWIST2 Rummagene Transcription Factor Associations 2026 1.0 null NCI-H748 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Atopic dermatitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.708 TP53INP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50587 recurrent viral infections GWASdb SNP-Phenotype Associations 1.0 0.630262 Ionocyte cell_Trachea_Mouse CellMarker Gene-Cell Type Associations 1.0 null Ammon's horn Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07153 H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE157594_3_v_2_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Field CA3, stratum lucidum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12289 whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.021254 CTCF_fibroblast of the aortic adventitia_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-513a-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.123298 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_fibroblast of pulmonary artery_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-8262-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE188870,GSE188871_1_v_5_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null NCIH2023 CCLE Cell Line Gene CNV Profiles 1.0 1.35489 CBX2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null recurrent infections GWASdb SNP-Phenotype Associations 1.0 0.29932 Perturb_8513_KO_Setd1b_SRP328849 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -16.4837 HESX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9806 nervous system disease GWASdb SNP-Disease Associations 1.0 0.053858 CTCF_BE2C_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12869_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null disease GWASdb SNP-Disease Associations 1.0 0.181793 Cerebral hemisphere TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.0 superficial stratum of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02289 22RV1 COSMIC Cell Line Gene Mutation Profiles 1.0 null LMX1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.46887 TEAD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9071 PHOSPHO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9306 Field CA2, stratum radiatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53373 MAZ ENCODE Transcription Factor Targets 1.0 null abnormal stomach epithelium morphology MPO Gene-Phenotype Associations 1.0 null H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ltk TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.629 PCGF2-27294783-CHIP-SEQ-NPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null gastric gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.608124 USP46 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.67445 GSE69244_1_v_0_j147_mouse RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A8RY-11A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TEF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6676 inorganic ion homeostasis GO Biological Process Annotations 2015 1.0 null CTCF_GM13977_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Endocervix TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.74 SUM52PE Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.602793 Lung squamous cell carcinoma_LUSC_TCGA-77-A5G7-01B-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null sodium ion transmembrane transport GO Biological Process Annotations 2023 1.0 null NOTO JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.984 Primary somatosensory area, mouth, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49525 GSE163809_1_v_2_sdhaf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE216043_10_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7469-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null monovalent cation:proton antiporter activity GO Molecular Function Annotations 2015 1.0 null Anterior olfactory nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.51081 CTCF_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null plasma membrane region GO Cellular Component Annotations 2015 1.0 null UBE2V2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.34589 Contact dermatitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.708 Renal vein TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.177 HOXD8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3025 POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.9721 CTCF_GM12872_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7862-01A-21R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMC1-22415368-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null terete nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74646 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5589-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE103068_5_v_7_volasertib_human RummaGEO Drug Perturbation Signatures 1.0 null LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44986 mantle zone of PalSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22157 H3K4me3_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 SMARCD1-25818293-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null COLO 320DM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.930271 496100530_FWM_dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.02888 GATA1_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC-mediated transmembrane transport Reactome Pathways 2014 1.0 null hsa-miR-4651 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GSE172016_2_v_0_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r2BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.75178 MAFK_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LHX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.065 gastrointestinal tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.087808 hsa-miR-608 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 LNCAP-CLONE-FGC COSMIC Cell Line Gene Mutation Profiles 1.0 null rectum HPA Tissue Protein Expression Profiles 1.0 1.46028 Leukocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.267 layer 3 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54735 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.430012 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SR-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PROSER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78656 GSE234340_12_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_GM06990_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Thymus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.937107 CTCF_GM12872_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null maintaining GeneRIF Biological Term Annotations 1.0 null Perturb_16359_OE_Ppargc1a_SRP278337 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 16.1898 MT-ND3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69415 GSE205976,GSE205978_1_v_4_cep83_human RummaGEO Gene Perturbation Signatures -1.0 null SG in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.15586 membrane LOCATE Predicted Protein Localization Annotations 1.0 null GSE238116_3_v_0_egr1_human RummaGEO Gene Perturbation Signatures 1.0 null EPLC-272H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.81409 GSE234340_10_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC8494348-pone.0257161.s002.xlsx-only_D20_-_OXT_NOT_ext-Gene_Name_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.363 MYC-27129775-CHIP-SEQ-CORNEA-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE217405_0_v_1_osimertinib_mouse RummaGEO Drug Perturbation Signatures 1.0 null chemical homeostasis GO Biological Process Annotations 2015 1.0 null COGAR359 DepMap CRISPR Gene Dependency 1.0 3.19389 GSE217405_3_v_2_osimertinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null Digestive juice TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.88 coronary artery disease GWASdb SNP-Disease Associations 1.0 0.414949 ZNF697 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.12685 Allergic contact dermatitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.708 CTCF_GM12870_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null gastric acid secretion GO Biological Process Annotations 2015 1.0 null Renal proximal tubule epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.922 GRANTA-519 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE154577_6_v_12_plagl1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE111247_0_v_6_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null Cortical collecting duct cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.947 Platelet alpha granule membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.667 Mesonephric duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.508 TBX20 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.3557 ZMIZ1 ENCODE Transcription Factor Targets 1.0 null Integument TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 CTCF_GM12871_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null leukocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Uterine fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.119 gastric mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.36526 GSE157594_6_v_2_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null osteoblasts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.66711 hsa-miR-4698 TargetScan Predicted Conserved microRNA Targets 1.0 0.181316 Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6988-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.6639 Perturb_12079_KO_Ezh2_SRP060232 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 12.0758 Postpiriform transition area, layers 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.65816 inner SZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.874309 SW48 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE234340_10_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Na+/H+ exchanger, isoform 2 (NHE2) InterPro Predicted Protein Domain Annotations 1.0 null RAGE_knockout_268_GDS3755 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.5417 Asthma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.028 Basolateral plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 CAMK2A Pathway Commons Protein-Protein Interactions 1.0 null SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0708 H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Connecting tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.559 CTCF_GM20000_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Asthma GWAS Catalog SNP-Phenotype Associations 2025 1.0 2.2 RAD21_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_15617_KO_Gaa_SRP286437 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -4.70697 CTCF_fibroblast of the aortic adventitia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 0.045062 CTCF_A549_hg19_10 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_MCF-7_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Renal tubular acidosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.501 HOXB6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.9027 NMYC-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Ulcerative colitis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.255 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null abnormality of cellular immune system GWASdb SNP-Phenotype Associations 1.0 0.122954 RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC-mediated transmembrane transport Reactome Pathways 2024 1.0 null GNG3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.02421 RFX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7526 Lateral visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03513 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Field CA3, stratum lacunosum-moleculare Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14497 Primary T cells from cord blood Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 0.962673 RAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1932 Lung squamous cell carcinoma_LUSC_TCGA-39-5021-01A-01R-1443-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r3Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19694 anteroventral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41029 solute:potassium antiporter activity GO Molecular Function Annotations 2025 1.0 null Tuberomammillary nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72531 Eccrine sweat gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.581 caudal presubiculum (postsubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.31524 Primary hematopoietic stem cells G-CSF-mobilized Male Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 2.2866 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053722 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Basal plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 Ectorhinal area/Layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2738 m2 part of substantia nigra compacta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18288 RBM15B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.19351 GSE246195,GSE246305_1_v_0_sin3a_mouse RummaGEO Gene Perturbation Signatures 1.0 null Gastric mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.9 NR3C1-21868756-MCF10A-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GSE173873_1_v_3_stra8_mouse RummaGEO Gene Perturbation Signatures 1.0 null thorax TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Field CA2, stratum oriens Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07153 EPC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96055 TT CCLE Cell Line Gene CNV Profiles 1.0 1.51432 SMC3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2009 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5711-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sox7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.2299 Hydrochloric Acid CTD Gene-Chemical Interactions 1.0 null CTCF_WI38_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5458-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pars recta TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.931 STT3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76733 intermediate stratum of m2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00405 periaqueductal gray substance, ventral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.50706 capable GeneRIF Biological Term Annotations 1.0 null Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.8395 GSE174418,GSE174421_2_v_3_mettl5_mouse RummaGEO Gene Perturbation Signatures -1.0 null lower respiratory tract disease GWASdb SNP-Disease Associations 1.0 0.906106 homeostatic process GO Biological Process Annotations 2015 1.0 null CDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2892 inorganic cation import across plasma membrane GO Biological Process Annotations 2023 1.0 null RAD21_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Gastrointestinal system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.946 Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.492 CTCF_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lateral septal nucleus, intermedio-intermediate part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14403 BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.70139 CTCF_kidney_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ectorhinal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28512 RH28 DepMap CRISPR Gene Dependency 1.0 2.35461 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053685 GSE87412,GSE92423_0_v_1_dnmt3a_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_human_DRSG_higherRes-Hg_gene_id_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Basolateral amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03028 PMC12126244-jci-135-184115-s239.xlsx-Table_3_Suppl_Fig_16-Genes_down-regulated_in_SOX9_low_tumors_744_genes_SOX9 Rummagene Transcription Factor Associations 2026 1.0 null PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-h-Classification_of_camel_SON_basal_genes_-_transporters_SON Rummagene Transcription Factor Associations 2026 1.0 null CAL78 CCLE Cell Line Gene CNV Profiles 1.0 1.76942 Head TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.333 CCDC107 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.11529 KATOIII CCLE Cell Line Gene CNV Profiles -1.0 -1.70872 GSE234340_4_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.6836 Retrosplenial area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05176 GSE199606_6_v_4_csf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null UMUC11 DepMap CRISPR Gene Dependency 1.0 2.60515 GSE213650_3_v_2_everolimus_human RummaGEO Drug Perturbation Signatures 1.0 null Ovary TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.267 NR3C1 ChEA Transcription Factor Targets 1.0 null abnormal stomach mucosa morphology MPO Gene-Phenotype Associations 1.0 null SNG-M COSMIC Cell Line Gene Mutation Profiles 1.0 null GATA6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.8899 Ebolavirus(ZEBOV)_6day_PBMCs_rhAPCtreated_21987740_GSE24943 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.02979 GSE137653_4_v_0_siglecf_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE240645_3_v_2_u90926_mouse RummaGEO Gene Perturbation Signatures -1.0 null PRRX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.5309 CTCF_skin fibroblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null FAM181B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24489 SMC3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 DMS454 CCLE Cell Line Gene CNV Profiles -1.0 -1.36901 Stat5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.8764 KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.00876 SMAD2/3-21741376-EPCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Fields of Forel Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14015 gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ATF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3897 VZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.845898 GSE234340_4_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null substantia nigra reticulata, m1 part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.94662 SG in granular insular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08468 TCCSUP DepMap CRISPR Gene Dependency 1.0 2.55649 GSE173873_1_v_6_stra8_mouse RummaGEO Gene Perturbation Signatures 1.0 null spinalcordupper BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.28212 abnormality of the skeletal system GWASdb SNP-Phenotype Associations 1.0 0.249898 Transport of inorganic cations/anions and amino acids/oligopeptides Reactome Pathways 2014 1.0 null disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.050801 Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3VY-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null t61-colon_consensus MoTrPAC Rat Endurance Exercise Training 1.0 1.82238 SOX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.7911 CTCF_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null carbohydrate metabolism disease GWASdb SNP-Disease Associations 1.0 0.248908 RAD21_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null carcinoma cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CTCF_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19488 blastomere TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.695763 KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.44532 E2F4_MCF 10A_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer V of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.65859 PPP2R1B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14774 Cochlear ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.761 cerebral lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060079 Posterolateral visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11279 MAFK ENCODE Transcription Factor Targets 1.0 null PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Sheet3-The_overlapping_genes_between_significantly_co-expressed_genes_and_significantly_differentially_expressed_genes_of_BARX2_in_LIHC_BARX2 Rummagene Transcription Factor Associations 2026 1.0 null EVSA-T COSMIC Cell Line Gene Mutation Profiles 1.0 null POU5F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.1463 Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A3-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Intestinal disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.85 HDAC6 ENCODE Transcription Factor Targets 1.0 null artery disease GWASdb SNP-Disease Associations 1.0 0.136733 RAD21_IMR-90_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF-26484167-CHIP-SEQ-BCELLS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SBNO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37814 endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null abnormality of cardiovascular system physiology GWASdb SNP-Phenotype Associations 1.0 0.336492 single-organism developmental process GO Biological Process Annotations 2015 1.0 null EOMES JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6888 496100339_HIP_no dementia_TBI_79_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.44475 substrate-specific transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null Acidosis CTD Gene-Disease Associations 1.0 2.88009 hsa-miR-3920 TargetScan Predicted Conserved microRNA Targets 1.0 0.568687 Tcf21 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.2648 U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.34708 TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4234 CTCF_bone marrow_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of the endocrine system GWASdb SNP-Phenotype Associations 1.0 0.072526 PKNOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.8812 inorganic cation transmembrane transport GO Biological Process Annotations 2023 1.0 null hsa-miR-3148 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 hsa-miR-4652-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 GRIN2D Pathway Commons Protein-Protein Interactions 1.0 null CTCF_LNCaP clone FGC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_12993_KO_Il1rl1_SRP274117 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.70164 layer VI of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.68905 HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.846918 VZ in posteror frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16336 Dlx2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.3842 PRRX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.3636 Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV7-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-PA-A5YG-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF214 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.0729 Median preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24547 CTCF_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Stomach TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.814 metabolic acidosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 1.07824 PMC10335677-pbio.3002161.s009.xls-MLL_siRNA_DEGs-Ensembl_Symbol_KMT2A Rummagene Transcription Factor Associations 2026 1.0 null PMC8020666-pnas.2015855118.sd09.xlsx-LPS_24_human_DRSG_higherRes-Ensemble_gene_id_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null CTCF_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TNIP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.09588 GSE234340_9_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null prepositus hypoglossal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.64841 nitrogen compound transport GO Biological Process Annotations 2025 1.0 null Estradiol CTD Gene-Chemical Interactions 1.0 null wide GeneRIF Biological Term Annotations 1.0 null kidney GTEx Tissue Gene Expression Profiles 1.0 1.08753 plasma membrane GO Cellular Component Annotations 2015 1.0 null cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 ZFHX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53867 CTCF_A549_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF143 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6792 GSE216538_0_v_2_mrs2_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCI-H920 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.35058 PHC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51546 CTCF ENCODE Transcription Factor Targets 1.0 null POU2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.695 A4 noradrenergic cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10687 KYSE-510 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null PBX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.1772 hsa-miR-3180-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 MET_knockout_251_GDS3148 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.97467 CTCF_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Field CA2, stratum lacunosum-moleculare Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02298 LMSU DepMap CRISPR Gene Dependency 1.0 4.85418 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3XD-01A-22R-A239-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null monovalent inorganic cation transport GO Biological Process Annotations 2015 1.0 null CTCF_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nah GeneRIF Biological Term Annotations 1.0 null GSE162276_5_v_3_rosiglitazone_mouse RummaGEO Drug Perturbation Signatures -1.0 null Primary somatosensory area, barrel field, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.339 CTCF_lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.33387 MPI CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.32755 CW-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE162892_3_v_0_sox9_human RummaGEO Gene Perturbation Signatures 1.0 null GSE173873_4_v_6_stra8_mouse RummaGEO Gene Perturbation Signatures 1.0 null precommissural nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.915534 NR2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2595 VAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.9627 t84 GeneRIF Biological Term Annotations 1.0 null gastrointestinal tract TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE139455_0_v_6_stat3_human RummaGEO Gene Perturbation Signatures -1.0 null GSE135350_3_v_1_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null CTCF_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PHF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83291 t70-white-adipose_consensus MoTrPAC Rat Endurance Exercise Training 1.0 1.52494 Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.07 Subiculum, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18157 Subfornical organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.135 SOX6-21985497-MYOTUBES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null KMS26 CCLE Cell Line Gene CNV Profiles -1.0 -1.76665 ion transport GO Biological Process Annotations 2015 1.0 null HOXA6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.3506 ZNF408 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36166 GSE211286_7_v_3_tcf12_mouse RummaGEO Gene Perturbation Signatures 1.0 null Cortical granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.977 superficial stratum of Mam Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.34675 CTCF_HeLa-S3_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null ACTN2 Pathway Commons Protein-Protein Interactions 1.0 null rostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07281 CTCF_GM12871_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_fibroblast of upper leg skin_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Tcf12 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.5421 Skin disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.708 RAD21-21589869-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GSE111247_2_v_6_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null KCNQ4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18732 BICR6 DepMap CRISPR Gene Dependency 1.0 3.97098 Prostate-hillock-club cell of prostate epithelium Tabula Sapiens Gene-Cell Associations 1.0 0.966872 Cluster of actin-based cell projections COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.724 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060124 NFKB1 JASPAR Predicted Transcription Factor Targets 1.0 null CTCF_kidney_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Deep Vein Thrombosis DisGeNET Gene-Disease Associations 1.0 null Plasma membrane region COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 Rectum adenocarcinoma_READ_TCGA-G5-6641-01A-11R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null myocardial infarction GWASdb SNP-Disease Associations 1.0 1.00407 IGR-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_fibroblast of villous mesenchyme_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lamina epithelialis mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.595 EZH2_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_6953_KD_Rbm20_ERP122940 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.86211 Parotid gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.043 Acute Myeloid Leukemia_LAML_TCGA-AB-2959-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.67101 CTCF_GM12873_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in midcingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29254 MZ in rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.04145 SNU182 DepMap CRISPR Gene Dependency 1.0 3.17377 NB(TU)1-10 COSMIC Cell Line Gene Mutation Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7424-11A-01R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DDA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.16364 EZH2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A6TU-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4716-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 CTCF_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A ENCODE Transcription Factor Targets 1.0 null MSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2898 Hmx1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.5883 Cystic fibrosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.33 mantle zone of r11Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.72682 EBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75615 COLO679 CCLE Cell Line Gene CNV Profiles -1.0 -1.98001 Corticobasal degeneration syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.211 inflammatory bowel disease GWASdb SNP-Disease Associations 1.0 1.71432 GSE100316_7_v_1_mtor_mouse RummaGEO Gene Perturbation Signatures -1.0 null connective tissue disease GWASdb SNP-Disease Associations 1.0 0.41938 H3K27me3_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SOX2_Deficiency_GDS4853_322_human_AZ-521 gastric cancer (GC) cell line - 24 Hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null congestive heart failure GWASdb SNP-Disease Associations 1.0 2.34245 Primary somatosensory area, barrel field Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16019 SG in rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10432 CTCF_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null TCF7L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.4169 Bisphosphonate-associated atypical femoral fracture GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.6 MKN7 CCLE Cell Line Gene CNV Profiles -1.0 -1.48479 DU 145 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.959988 Night sleep phenotypes GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.504576 MOGGCCM CCLE Cell Line Gene CNV Profiles -1.0 -1.43415 homeostasis GeneRIF Biological Term Annotations 1.0 null VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00977 Pax7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.006 monovalent inorganic cation transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null Male reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.967 JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.9519 nhe1 GeneRIF Biological Term Annotations 1.0 null Cation/H+ exchanger InterPro Predicted Protein Domain Annotations 1.0 null potassium ion transmembrane transport GO Biological Process Annotations 2025 1.0 null Endolysosome lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.563 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7437-11A-01R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null breast cancer cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MAF-26560356-CHIP-SEQ-TH1-HUMAN ChEA Transcription Factor Targets 2022 1.0 null VZ in inferolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.98289 pineal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.621831 decreased bone mineral density IMPC Knockout Mouse Phenotypes 1.0 null Brush border COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.766 dorsolateral part of Int Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29891 Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_MEL cell line_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-7221-01A-11R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Subiculum, ventral part, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28667 NFE2-27457419-CHIP-SEQ-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Uterine luminal fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.984 STAT3_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HOXD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.8336 GATA1 ENCODE Transcription Factor Targets 1.0 null hydrogen ion transmembrane transport GO Biological Process Annotations 2015 1.0 null GSE145639_1_v_4_adar_human RummaGEO Gene Perturbation Signatures -1.0 null Supraoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31171 BICR 78 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26404 CTCF_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null developmental process GO Biological Process Annotations 2015 1.0 null epithelial cell development GO Biological Process Annotations 2015 1.0 null gastric necrosis MPO Gene-Phenotype Associations 1.0 null CTCF_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null metal cation:proton antiporter activity GO Molecular Function Annotations 2023 1.0 null EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.3252 Entorhinal area, medial part, ventral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12779 PCBP1_02_137 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.0 GRB10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.6747 chr2_102468797_C_G_b38 GTEx eQTL 2025 1.0 4.25831 Collecting duct cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.546 NCI-H1573 COSMIC Cell Line Gene Mutation Profiles 1.0 null Apoplast COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.784 Brain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.0 superficial stratum of isBI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.99401 STAT3-18555785-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Apical plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.685 sodium ion transmembrane transporter activity GO Molecular Function Annotations 2025 1.0 null Rhomboid nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.596 SETDB1_KO_GSE40296_7_mouse_brain (telencephalon) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Sense organ TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.333 Perturb_14376_KD_MECOM_SRP276625 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -1.58861 Secretory diarrhea DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.637 EW-13 COSMIC Cell Line Gene Mutation Profiles 1.0 null H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE207514,GSE207515_0_v_3_acetylcysteine_human RummaGEO Drug Perturbation Signatures -1.0 null intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null establishment of localization GO Biological Process Annotations 2015 1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.636 membrane GO Cellular Component Annotations 2015 1.0 null r8 part of inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01346 hydrogen transport GO Biological Process Annotations 2015 1.0 null ZNF24 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.5266 Rhoptry COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.634 Stomach TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE164757,GSE164759_1_v_0_trametinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null RAD21_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null celiac disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.790827 SUZ12-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null Basal plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.524 sodium ion transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null H513 COSMIC Cell Line Gene Mutation Profiles 1.0 null hsa-miR-4509 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 LHX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.7158 Anterolateral visual area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21948 cell part GO Cellular Component Annotations 2015 1.0 null stomach_a HPA Tissue Sample Gene Expression Profiles 1.0 1.63188 Perturb_1261_KO_Ahnak_SRP307472 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.8041 RAD21_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH522 CCLE Cell Line Gene CNV Profiles 1.0 2.5919 OlfactoryBulb BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.891747 abnormality of the immune system GWASdb SNP-Phenotype Associations 1.0 1.36628 r4 part of ventral lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60437 SNU5 DepMap CRISPR Gene Dependency 1.0 2.79565 eosinophils GAD Gene-Disease Associations 1.0 null White blood cell types GWAS Catalog SNP-Phenotype Associations 1.0 0.057619 Nucleus preopticus medianus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.784 CISD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.78149 KYSE-270 COSMIC Cell Line Gene Mutation Profiles 1.0 null ZNF728 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.44209 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null PMC11906354-41588_2025_2087_MOESM4_ESM.xlsx-ST12-Unnamed_3_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null Glioblastoma HuGE Navigator Gene-Phenotype Associations 1.0 null cell development GO Biological Process Annotations 2015 1.0 null sodium ion transport GO Biological Process Annotations 2015 1.0 null GSE131161_2_v_4_rarres1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Cortical collecting duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.672 TLCD2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.83439 PMC12956708-DataSheet1.xlsx-Supplementary_Table_6-Supplementary_Table_5_The_DEGs_from_sea_level_between_AMS_and_non-eAMS_group_of_GSE75665_TWIST2 Rummagene Transcription Factor Associations 2026 1.0 null Celiac disease GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.752288 CTCF_fibroblast of pedal digit skin_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21 ChEA Transcription Factor Targets 1.0 null lateropallial prepiriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14312 UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01078 NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.79507 H3K4me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Interleukin 1 Receptor-Like 1 Measurement DisGeNET Gene-Phenotype Associations 1.0 null EBF1-22473956-LYMPHODE-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Uterine endometrial epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.792 intestinal disease GWASdb SNP-Disease Associations 1.0 1.36515 RBM28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13269 CTCF_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.2976 Lung adenocarcinoma_LUAD_TCGA-75-7030-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE100316_7_v_6_mtor_mouse RummaGEO Gene Perturbation Signatures 1.0 null Cell projection membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.559 Brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.043 MNX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.8052 Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE234340_1_v_2_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null NCI-H1770 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.847845 Spindle envelope COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.848 CTCF_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dermatitis DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.708 MRPS18A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.51246 NCI-H441 COSMIC Cell Line Gene Mutation Profiles 1.0 null Lhx3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 45.65 Tuberomammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.92101 Kdm1a_KD_GDS5055_275_mouse_3T3-L1 preadipocytes - 48h GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null CMYC-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null superficial stratum of r1BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.10606 PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB Rummagene Transcription Factor Associations 2026 1.0 null SW684 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC9314343-41467_2022_31892_MOESM8_ESM.xlsx-Fig7e-CTCF_in_promoter_CTCF Rummagene Transcription Factor Associations 2026 1.0 null CTCF_lung_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5696-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE228162_2_v_5_nr2f6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.946 Retrosplenial area, lateral agranular part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.71293 SIPA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17141 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SL-01A-21R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5580-11A-02R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HS 746T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.22674 Hypertension DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.206 TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Perturb_15284_KO_Trp73_SRP067006 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.01648 PMC3303130-NIHMS40463-supplement-4.xls-KamKwaMuk_AA_differences-human_geneID_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR Rummagene Transcription Factor Associations 2026 1.0 null OVCAR8 CCLE Cell Line Gene CNV Profiles 1.0 1.69052 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01078 GSE91015_0_v_1_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null Male reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.967 CTCF_MCF-7_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null Respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.056 CTCF_K562_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBL1XR1 ENCODE Transcription Factor Targets 1.0 null GSE157594_3_v_4_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null GFI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1139 Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PF-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE100316_3_v_2_mtor_mouse RummaGEO Gene Perturbation Signatures -1.0 null celiac disease GWASdb SNP-Disease Associations 1.0 0.614068 GSE228727_2_v_1_dapagliflozin_mouse RummaGEO Drug Perturbation Signatures 1.0 null Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.072 stomach_3b HPA Tissue Sample Gene Expression Profiles 1.0 1.61508 lateral amygdaloid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.13658 sodium ion transmembrane transport GO Biological Process Annotations 2015 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-A4BX-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Retrosplenial area, lateral agranular part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01656 cellular developmental process GO Biological Process Annotations 2015 1.0 null ventral part of PHyB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64319 abnormality of the lung GWASdb SNP-Phenotype Associations 1.0 0.411606 Anterolateral visual area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50428 morula TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.908387 Microvillus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.395 cellular GeneRIF Biological Term Annotations 1.0 null Perturb_12085_OE_Cyp19a1_SRP050547 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -12.5465 496100368_PCx_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.51131 P53-22387025-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NCI-H1092 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32703 CTCF_fibroblast of lung_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null DB DepMap CRISPR Gene Dependency 1.0 9.00811 GSE145639_1_v_2_adar_human RummaGEO Gene Perturbation Signatures -1.0 null Gonad TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.967 Temporal association areas, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47367 lactic acidosis DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.99908 MYC-19915707-AK7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE207135_2_v_0_sod2_human RummaGEO Gene Perturbation Signatures 1.0 null HCC2302 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.73302 Macula densa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.908 WDR82 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.56877 SKUT1 DepMap CRISPR Gene Dependency 1.0 3.35789 hydrogen ion transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null AMER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.18516 Renal epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.366 CTCF_GM12878_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null LOUNH91 DepMap CRISPR Gene Dependency 1.0 2.31552 abnormality of blood and blood-forming tissues GWASdb SNP-Phenotype Associations 1.0 0.062104 placenta BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.937054 Pheochromocytoma and Paraganglioma_PCPG_TCGA-RM-A68W-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null potassium:proton antiporter activity GO Molecular Function Annotations 2023 1.0 null EW8 CCLE Cell Line Gene CNV Profiles 1.0 2.14738 MGA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3271 SMC3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNRNPDL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.11452 ZNF143_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KARPAS1718 DepMap CRISPR Gene Dependency 1.0 2.33172 GSE103068_5_v_4_volasertib_human RummaGEO Drug Perturbation Signatures 1.0 null hsa-miR-576-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 SHOX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6759 mantle zone of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.64271 MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE125219,GSE125221_4_v_2_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null Perturb_8373_OE_AC093797.1_SRP344034 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -18.9208 CTCF_fibroblast of skin of abdomen_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null colitis GWASdb SNP-Phenotype Associations 1.0 1.92507 HCC3153 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.753678 NR2C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.7795 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8ZZ-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney Chromophobe_KICH_TCGA-KM-8441-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Supplemental somatosensory area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.55375 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.957922 Acute Myeloid Leukemia_LAML_TCGA-AB-3006-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056319 Acute Myeloid Leukemia_LAML_TCGA-AB-2845-03B-01T-0748-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RUNX1-27457419-CHIP-SEQ-LIVER-MOUSE ChEA Transcription Factor Targets 2022 1.0 null EP300_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null SG in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.05563 OCT4-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null TBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4299 Postpiriform transition area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67212 GSE121824,GSE121826_0_v_8_scaf8_human RummaGEO Gene Perturbation Signatures 1.0 null periventricular stratum of PalSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18288 Apical part of cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.248 Transmembrane transport of small molecules Reactome Pathways 2014 1.0 null animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.021153 GSE124410_3_v_4_stk40_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_9614_KO_Rprd1b_SRP241887 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.0215 Field CA3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51546 CTCF_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skeletal Muscle Female Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.882081 cellular process GO Biological Process Annotations 2015 1.0 null Celiac Disease DisGeNET Gene-Disease Associations 1.0 null shell part of the anterobasal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27192 FAAH CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20576 HAP-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.839 SUM1315MO2 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.06751 DBTRG05MG CCLE Cell Line Gene CNV Profiles -1.0 -1.84015 hsa-miR-27b TargetScan Predicted Conserved microRNA Targets 1.0 0.136254 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner CP in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.86874 intermediate stratum of PalSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14694 MB1 DepMap CRISPR Gene Dependency 1.0 3.52306 Entorhinal area, medial part, ventral zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02142 CTCF_GM12865_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5691-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Field CA3, stratum radiatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66862 Carbohydrate metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.113 zygote TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.151032 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE139975_3_v_0_rnf2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Fetal Brain Male Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.47452 hsa-miR-30c TargetScan Predicted Conserved microRNA Targets 1.0 0.165047 Superior olivary complex, periolivary region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04858 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5694-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LAMA84 CCLE Cell Line Gene CNV Profiles -1.0 -1.36833 cation-transporting ATPase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.717 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5705-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null oxyntic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.690859 layer 2 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07782 intracellular GeneRIF Biological Term Annotations 1.0 null Lymphocyte count GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.52218 solute:potassium antiporter activity GO Molecular Function Annotations 2023 1.0 null GSE192689_0_v_2_ricin_mouse RummaGEO Drug Perturbation Signatures -1.0 null secretion GO Biological Process Annotations 2015 1.0 null epithelial cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CTCF_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11615365-41467_2024_54246_MOESM5_ESM.xlsx-RT112-Numb-KD_vs_Ctr-KD-geneSymbol_AR Rummagene Transcription Factor Associations 2026 1.0 null mantle zone of TSPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26473 GSE217405_0_v_1_egfr_mouse RummaGEO Gene Perturbation Signatures 1.0 null abnormality of the gastrointestinal tract GWASdb SNP-Phenotype Associations 1.0 0.358036 MEF2A JASPAR Predicted Transcription Factor Targets 1.0 null ADD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44579 GSE191174_0_v_1_ccdc92_mouse RummaGEO Gene Perturbation Signatures -1.0 null HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27851 Integumentary system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.708 CXorf38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.52222 SNU738 CCLE Cell Line Gene CNV Profiles 1.0 2.34257 HCC44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02806 LMBR1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23871 Adrenocortical carcinoma_ACC_TCGA-OR-A5JA-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMAD4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5566 PK-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09782 CTCF_MCF-7_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE232223_1_v_0_letmd1_mouse RummaGEO Gene Perturbation Signatures 1.0 null medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.41548 HUH-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null SMC3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CST complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.656 MAZ_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.2401 MEL-JUSO COSMIC Cell Line Gene Mutation Profiles 1.0 null disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.790827 Small_Intestine-paneth cell of epithelium of small intestine Tabula Sapiens Gene-Cell Associations 1.0 2.59122 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null Perturb_10609_KO_Rbm20_SRP124759 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -3.71941 ZYX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.5331 single-organism process GO Biological Process Annotations 2015 1.0 null FGF19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09394 CTCF_epithelial cell of proximal tubule_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OVMANA CCLE Cell Line Gene CNV Profiles 1.0 1.47417 kidney_b HPA Tissue Sample Gene Expression Profiles 1.0 1.01476 SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18618 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20F-06A-21R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A42Y-01A-12R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26506 NCI-H2106 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.86098 GSE125219,GSE125221_3_v_0_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null ventral tegmental area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.986947 CTCF_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inorganic cation transmembrane transport GO Biological Process Annotations 2015 1.0 null GSE147366_1_v_4_med13_human RummaGEO Gene Perturbation Signatures 1.0 null MIXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.3459 Sodium HMDB Metabolites of Enzymes 1.0 null GSE162892_4_v_0_isox_human RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5875-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BEN CCLE Cell Line Gene CNV Profiles 1.0 1.59402 CTCF_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of r4BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56213 heart GTEx Tissue Gene Expression Profiles -1.0 -1.20104 DETROIT 562 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27174 Lhx4 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 14.093 Junctional membrane complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.597 PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53 Rummagene Transcription Factor Associations 2026 1.0 null NOB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9819 TRIB1_KO_GDS2944_555_mouse_Macrophages GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2936-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3-7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.36212 GSE199606_5_v_4_csf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-30e TargetScan Predicted Conserved microRNA Targets 1.0 0.187098 liver TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.0758 cldependent GeneRIF Biological Term Annotations 1.0 null germ cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.07155 BT20 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.965941 Inflammatory bowel disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.27 COPS8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.18368 integument TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null CTCF_GM12864_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.958527 r3 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.99125 ALX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.4789 ZNF354A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 61.5992 Cervicovaginal fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.926 gastric epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.841608 metal ion transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null EP300 ENCODE Transcription Factor Targets 1.0 null intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10158025-ijbsv19p2081s6.xlsx-SupTable5-ZBTB20_ZBTB20 Rummagene Transcription Factor Associations 2026 1.0 null HOXA3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5688 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052699 GSE166294_0_v_1_etv5_mouse RummaGEO Gene Perturbation Signatures 1.0 null nhe GeneRIF Biological Term Annotations 1.0 null layer 1 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.46588 TEAD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2492 cardiovascular system disease GWASdb SNP-Disease Associations 1.0 0.323965 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.73302 90S preribosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.737 AKAP9 Pathway Commons Protein-Protein Interactions 1.0 null SA1-22415368-MEFS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CTCF_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A3PH-01A-11R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null blastocyst TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.426872 CHUK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.93528 SK-MES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17253 21NT DepMap CRISPR Gene Dependency 1.0 2.27 UHMK1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.27615 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Entorhinal area, lateral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70089 type ii diabetes mellitus GWASdb SNP-Phenotype Associations 1.0 0.484947 CTCF-18555785-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null SP in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.960568 Perturb_797_KO_Tnfaip3_SRP332632 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 GSE60837_2_v_3_bcl9_mouse RummaGEO Gene Perturbation Signatures 1.0 null blood TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Primary somatosensory area, barrel field, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2738 EC-GI-10 COSMIC Cell Line Gene CNV Profiles 1.0 4.51153 central part of CEl Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.927285 PMC9314343-41467_2022_31892_MOESM8_ESM.xlsx-FigS7d-CTCF_in_promoter_CTCF Rummagene Transcription Factor Associations 2026 1.0 null lateral dorsal nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.83085 COLO792 DepMap CRISPR Gene Dependency 1.0 3.029 PMC9533694-MOL2-16-3410-s013.xlsx-FIR20vsREST_DEMs-FIR20_vs_REST_DEMs_Up_REST Rummagene Transcription Factor Associations 2026 1.0 null ZNF136 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.7791 Foxo1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.075 CTCF_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE227415_1_v_0_ucp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.18545 FLI1::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.897 congestive heart failure GWASdb SNP-Phenotype Associations 1.0 2.3201 GSE234340_12_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Protons CTD Gene-Chemical Interactions 1.0 null stomach HPA Tissue Gene Expression Profiles 1.0 1.52861 GSE218356_1_v_0_cited1_mouse RummaGEO Gene Perturbation Signatures -1.0 null bone inflammation disease GWASdb SNP-Disease Associations 1.0 1.12412 GSE166004_5_v_6_pld1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SW 948 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.27174 H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null three GeneRIF Biological Term Annotations 1.0 null Connecting tubule cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.788 SCLC-22H Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50842 MG63 DepMap CRISPR Gene Dependency 1.0 2.82167 HS 578T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.847845 MCF12A Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.825355 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040321 CTCF_epithelial cell of esophagus_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE178714_5_v_7_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE166536_1_v_2_docetaxel_mouse RummaGEO Drug Perturbation Signatures 1.0 null GPR160 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.82315 G-402 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54822 superior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.122 GSE196199_0_v_1_zbtb20_mouse RummaGEO Gene Perturbation Signatures 1.0 null Bed nuclei of the stria terminalis, posterior division, strial extension Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4495 CTCF_HCT116_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Endopiriform nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28055 LS123 CCLE Cell Line Gene CNV Profiles 1.0 1.61549 496100464_FWM_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.02816 LBX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.0336 SIN3A_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial stratum of LAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.85608 HCC1428 CCLE Cell Line Gene CNV Profiles 1.0 1.65096 PHOX2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.5325 decreased bone mineral content MGI Mouse Phenotype Associations 2023 1.0 null GATA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.5124 potassium:proton antiporter activity GO Molecular Function Annotations 2025 1.0 null CTCF_fibroblast of lung_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZC3H11A ENCODE Transcription Factor Targets 1.0 null Inflammatory bowel disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.85 CDX2-21402776-INTESTINAL-VILLUS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE127790_11_v_2_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null superficial stratum of ERCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30827 VZ in caudal cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.04126 GSE185519_4_v_7_gilteritinib_human RummaGEO Drug Perturbation Signatures 1.0 null arthritis GWASdb SNP-Phenotype Associations 1.0 2.3201 CTCF_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null excretory gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE141726,GSE141733_1_v_0_angiotensin ii_mouse RummaGEO Drug Perturbation Signatures 1.0 null Triangular nucleus of septum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08688 SW1573 COSMIC Cell Line Gene Mutation Profiles 1.0 null 42MGBA DepMap CRISPR Gene Dependency 1.0 2.78065 UNCX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2846 SMAD1-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE235587_2_v_1_mitoxantrone_human RummaGEO Drug Perturbation Signatures 1.0 null metal ion transport GO Biological Process Annotations 2015 1.0 null GSE149035_3_v_5_hepacam_human RummaGEO Gene Perturbation Signatures -1.0 null Ureter TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.918 CHP1 Pathway Commons Protein-Protein Interactions 1.0 null EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null UBR7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.78125 Acidosis DisGeNET Gene-Phenotype Associations 1.0 null ICC2 DepMap CRISPR Gene Dependency 1.0 7.37232 Testis TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.967 GSE255680_1_v_0_igf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.127 HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.6524 CTCF_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DLG4 Pathway Commons Protein-Protein Interactions 1.0 null CTCF_fibroblast of gingiva_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ENDOV CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.33253 STAT3_MCF 10A_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null integral component of membrane GO Cellular Component Annotations 2015 1.0 null GSE149903_6_v_2_myd88_mouse RummaGEO Gene Perturbation Signatures 1.0 null cell projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.053222 CTCF_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormal inflammatory response MPO Gene-Phenotype Associations 1.0 null EP300-21415370-HL-1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CTCF_GM12865_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE199606_3_v_4_ricin_mouse RummaGEO Drug Perturbation Signatures -1.0 null CTCF_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null KYSE150 DepMap CRISPR Gene Dependency 1.0 4.06189 inorganic ion transmembrane transport GO Biological Process Annotations 2015 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JL-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HS695T DepMap CRISPR Gene Dependency 1.0 2.32046 HS746T CCLE Cell Line Gene CNV Profiles -1.0 -1.66547 bronchial disease GWASdb SNP-Disease Associations 1.0 2.34245 SMAD4-21741376-EPCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null digestive system process GO Biological Process Annotations 2015 1.0 null H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 496100497_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.15985 H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-5643-01A-01R-1628-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-6405-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pineal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.536 lymphocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 Allergic disease (asthma, hay fever or eczema) GWAS Catalog SNP-Phenotype Associations 2025 1.0 2.33979 superficial stratum of r11Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.72443 Orbital area, lateral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11279 Orbital area, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58724 Exocrine pancreas TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.18 Nucleus preopticus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.601 OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.26404 GSE188870,GSE188871_0_v_5_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-3168 TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 hsa-miR-567 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 SW1783 COSMIC Cell Line Gene Mutation Profiles 1.0 null basolateral amygdaloid nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.15417 Anteroventral periventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08134 Vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.346 pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.866492 diencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.124231 RAD21_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Appendicular lean mass GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.5699 SIN3A ENCODE Transcription Factor Targets 1.0 null suprachiasmatic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2133 H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CUX1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0388 NB1 COSMIC Cell Line Gene Mutation Profiles 1.0 null STAT5-23275557-MAMMARY-EPITHELIUM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null MON1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.0845 MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.05084 Rectum adenocarcinoma_READ_TCGA-AG-3591-01A-01R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PAX3_Knock-in_GDS3331_598_mouse_Palatal shelves (E14.5 embryos - palate) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Primary immunodeficiency disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.946 CTCF_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null OCT4-21477851-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NR2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 62.2203 FADS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17728 CTCF_MCF-7_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null MDAMB436 CCLE Cell Line Gene CNV Profiles 1.0 2.11088 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null CTCF_HepG2_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5697-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CatSper complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.746 Nodulus (X), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4932 retina BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.846762 AKT1_OE_GDS2308_508_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null SARC9371 COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K27me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anterolateral visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17573 disease of metabolism GWASdb SNP-Disease Associations 1.0 0.083277 PMC9498168__F6a PFOCR Pathway Figure Associations 2024 1.0 null CTCF_HepG2_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-CI-6620-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU3F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.2336 hsa-miR-3074-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 CTV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null active transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null stomach TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.161135 efo21 HPA Cell Line Gene Expression Profiles 1.0 0.972393 Intercalated cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.715 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 Bed nuclei of the stria terminalis, anterior division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0102 Hypokalemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.346 periaqueductal gray substance, dorsolateral portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.36484 STARD3NL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.96181 CTCF_bone marrow macrophage_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null gastrointestinal system disease GWASdb SNP-Disease Associations 1.0 0.390919 GSE149264,GSE149267_9_v_3_trp53_mouse RummaGEO Gene Perturbation Signatures 1.0 null Sodium/Proton exchangers Reactome Pathways 2024 1.0 null JHOC5 CCLE Cell Line Gene CNV Profiles 1.0 1.61784 SNX18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43547 celiac disease GAD Gene-Disease Associations 1.0 null abomasum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.352227 anterior olfactory area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02129 Field CA1, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54315 GSE234340_1_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null BARX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9606 intermediate stratum of LAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31627 CTCF_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Right colon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.993 Pinealocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.791 GSE175787_4_v_0_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null Celiac disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.213 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormal mucous neck cell morphology MGI Mouse Phenotype Associations 2023 1.0 null Basolateral amygdalar nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37763 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GPR120_KO_GDS4830_413_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null DU145 DepMap CRISPR Gene Dependency 1.0 2.80138 OCIMY5 CCLE Cell Line Gene CNV Profiles -1.0 -1.85013 KARPAS-620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38878 CTCF ChEA Transcription Factor Targets 1.0 null GSE132759_4_v_2_fgfr1_mouse RummaGEO Gene Perturbation Signatures 1.0 null RAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2763 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A1HR-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null anterior pretectal nucleus, ventral superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0548 GSE119498_0_v_5_setd5_mouse RummaGEO Gene Perturbation Signatures 1.0 null stomach TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Brain - Putamen (basal ganglia) GTEx Tissue Gene Expression Profiles 2023 1.0 6.87573 LU165 DepMap CRISPR Gene Dependency 1.0 4.10477 Collecting duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.072 Hnf1a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 31.233 NR4A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.1648 GSE216147_2_v_1_rbm20_mouse RummaGEO Gene Perturbation Signatures -1.0 null Immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.213 hippocampus (cortex Ammonis) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14807 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38878 PCGF2-27294783-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null anteroventral periventricular preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42734 MPP89 CCLE Cell Line Gene CNV Profiles -1.0 -1.61965 CTCF_GM12866_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_brain microvascular endothelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.847845 Inner medullary collecting duct cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.144 CHN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40991 NAMALWA DepMap CRISPR Gene Dependency 1.0 2.95079 VZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.91985 CTCF_fibroblast of mammary gland_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.067 GSE162892_4_v_0_sox9_human RummaGEO Gene Perturbation Signatures 1.0 null CTCF_foreskin fibroblast_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12869_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null r11 part of spinal trigeminal nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.72208 Eye TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.333 hypersensitivity reaction disease GWASdb SNP-Disease Associations 1.0 1.51917 H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null DCK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.65705 HUCCT1 CCLE Cell Line Gene CNV Profiles -1.0 -1.43415 CTCF_medulloblastoma_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HDAC2_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12872_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null stratum radiatum of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.5542 GK_KO_GDS1555_127_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HSSCH2 DepMap CRISPR Gene Dependency 1.0 3.38102 Rectum adenocarcinoma_READ_TCGA-F5-6814-01A-31R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lymphoma_burkitts(Daudi) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.841488 NCI-H2110 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.960867 b-lymphocyte TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 CMK115 DepMap CRISPR Gene Dependency 1.0 3.70419 GSE192870_2_v_0_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null posterior cortical nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17525 GSE119498_6_v_4_setd5_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_pancreas_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TP53 JASPAR Predicted Transcription Factor Targets 1.0 null stomach inflammation MGI Mouse Phenotype Associations 2023 1.0 null ZNF217 ChEA Transcription Factor Targets 1.0 null PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null microcellular tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.16879 Gastritis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.197 STAT3-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null r10 part of the vestibular column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17573 Blood TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.267 Gastric ulcer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.99 SARNP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59848 CTCF_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RIPPLY1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62732 MGE-Lateral region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 3.33108 Internal male genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.967 Reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.345 CTCF_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Immune system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.946 Artery disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.277 GSE207135_1_v_0_sod2_human RummaGEO Gene Perturbation Signatures 1.0 null CTCF_LNCaP clone FGC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_17475_KO_Ubr4_SRP259313 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.36165 Perturb_951_KO_Suz12_SRP322809 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -19.301 Perturb_796_KO_Tnfaip3_SRP332632 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Superior colliculus, superficial gray layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10883 hsa-miR-3664-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.883892 breast TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.173 liminal reticular formation of m2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56334 Perturb_6365_KO_Hnrnpu_SRP250313 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.02152 JIMT1 CCLE Cell Line Gene CNV Profiles 1.0 1.74606 ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RGM-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.645 NCI-H2023 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.33779 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null abnormal gastric chief cell morphology MGI Mouse Phenotype Associations 2023 1.0 null transmembrane transport GO Biological Process Annotations 2015 1.0 null LOX-IMVI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.9569 Zymogen granule membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.301 heart disease GWASdb SNP-Disease Associations 1.0 0.730753 GSE234340_9_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GCLC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54541 hsa-miR-3920 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GSE166004_5_v_4_pld1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Colon descendens TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.751 abnormal gastric parietal cell morphology MGI Mouse Phenotype Associations 2023 1.0 null Arid3a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.6667 CTCF_WI38_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null YY1 ENCODE Transcription Factor Targets 1.0 null ANKRD49 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.84696 CTCF_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Asthma or allergic disease (pleiotropy) GWAS Catalog SNP-Phenotype Associations 2025 1.0 2.6699 HSPA4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.86257 superficial stratum of r2Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46413 RORA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.3389 ZNF324 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.1146 SPIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.2691 Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6088-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KELLY CCLE Cell Line Gene CNV Profiles -1.0 -2.05414 EFM19 DepMap CRISPR Gene Dependency 1.0 2.19818 Female reproductive system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.345 STAT1::STAT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.7806 H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the abdomen GWASdb SNP-Phenotype Associations 1.0 0.262134 GSE147366_1_v_2_med13_human RummaGEO Gene Perturbation Signatures 1.0 null Microneme COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.654 SW982 COSMIC Cell Line Gene Mutation Profiles 1.0 null Prostate gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.133 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.237908 inner portion of lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.82968 KYSE-180 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00091 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 DUX4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.5201 FOXD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.4315 oculomotor nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06108 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5984-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HNF4 MotifMap Predicted Transcription Factor Targets 1.0 null GSE181966_0_v_3_has2_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-3591-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 CTCF-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Epithalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.47 GSE147943_0_v_3_cited2_mouse RummaGEO Gene Perturbation Signatures 1.0 null substantia nigra reticulata, isthmic part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.99308 superficial stratum of THyB-I Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.35767 CTCF_MEL cell line_mm9_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-3009-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE173873_8_v_13_stra8_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE192870_2_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Vaginal fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.789 ZBTB26 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50547 Entorhinal area, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.8507 Zymogen granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.561 Cerebral lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.0 gametocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.070871 GSE234289_3_v_2_rfx6_human RummaGEO Gene Perturbation Signatures 1.0 null GSE145915_5_v_4_pcm1_mouse RummaGEO Gene Perturbation Signatures -1.0 null RPL29 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.15908 rat GeneRIF Biological Term Annotations 1.0 null CTCF_HEK293_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.2777 urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null superficial stratum of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37943 IRF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 4.17794 abnormal glucose homeostasis GWASdb SNP-Phenotype Associations 1.0 0.190469 GSE63857_3_v_1_tamoxifen_mouse RummaGEO Drug Perturbation Signatures -1.0 null POU6F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 52.5557 ESRRB-18555785-CHIP-SEQ-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null STAT1 JASPAR Predicted Transcription Factor Targets 1.0 null KYSE-140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.32703 SUZ12-27294783-CHIP-SEQ-NPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Yy1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.3161 Eosinophils dbGAP Gene-Trait Associations 1.0 0.323533 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Endopiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08017 UMUC9 DepMap CRISPR Gene Dependency 1.0 2.49659 Prdm14 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.9445 CTCF_astrocyte of the cerebellum_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2939-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KLF5-25053715-YYC3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null inner SZ in posteroinferior (ventral) parietal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.20563 OK cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.678 Dense body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.63 496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.0607 Left colon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.936 subbrachial nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09166 monovalent inorganic cation homeostasis GO Biological Process Annotations 2015 1.0 null Stat6 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 40.1037 CTCF_WERI-Rb-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU6F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.1182 STAT5A ChEA Transcription Factor Targets 1.0 null crohn's disease GWASdb SNP-Phenotype Associations 1.0 0.521292 Inner medullary collecting duct TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.739 STAT5-23275557-MAMMARY-EPITHELIUM-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null abnormal stomach morphology MPO Gene-Phenotype Associations 1.0 null hsa-miR-548l TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 Kidney Chromophobe_KICH_TCGA-KN-8422-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE217115_3_v_5_alectinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC5059470-ncomms12992-s6.xlsx-CRS-NOCRS-Supplementary_Data_5_Integration_Frequency_in_cirrhotic_CRS_and_non-cirrhotic_no-CRS_Tumor_Samples_TWIST1 Rummagene Transcription Factor Associations 2026 1.0 null Bed nuclei of the stria terminalis, anterior division, anteromedial area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48044 MYC ENCODE Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5452-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_astrocyte of the spinal cord_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE145639_1_v_6_adar_human RummaGEO Gene Perturbation Signatures -1.0 null GSE111102,GSE111105_3_v_5_pparg_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Field CA2, stratum pyramidale Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.64233 hematopoietic cell TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 CTCF_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE234340_3_v_7_muc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07409 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5706-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null layer IIIu of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12045 pinealocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.828616 biological_process GO Biological Process Annotations 2015 1.0 null GSE181966_5_v_3_has2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6134-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR6A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.9755 apical plasma membrane GO Cellular Component Annotations 2015 1.0 null ZNF217-24962896-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE147366_3_v_5_med13_human RummaGEO Gene Perturbation Signatures 1.0 null embryoday10.5 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23083 subbrachial nucleus, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05868 Superior colliculus, sensory related Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04492 ATCAY CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.25933 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A4ZT-11A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2806-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inflammation of the large intestine GWASdb SNP-Phenotype Associations 1.0 1.92507 Nephron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.94 CTCF_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IPC-298 COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_GM12868_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE88819_11_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Rectum adenocarcinoma_READ_TCGA-DC-4745-01A-01R-A32Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5356 H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EPLC272H CCLE Cell Line Gene CNV Profiles 1.0 1.49608 H3K4me1_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null T47D Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.52999 CTCF_GM12870_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.182 EZH2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Temporal association areas, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58288 Cation/H+ exchanger, CPA1 family InterPro Predicted Protein Domain Annotations 1.0 null H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lingula (I), granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08134 cation homeostasis GO Biological Process Annotations 2015 1.0 null HNF1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.7728 hsa-miR-526b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 hypochlorhydria MPO Gene-Phenotype Associations 1.0 null ion transmembrane transport GO Biological Process Annotations 2015 1.0 null MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.5271 viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060494 ZC3H11A_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Transport of small molecules Reactome Pathways 2024 1.0 null VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.83256 HDAC2 ENCODE Transcription Factor Targets 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H522 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 3.19301 superficial stratum of r3BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.98988 HCC1954 COSMIC Cell Line Gene Mutation Profiles 1.0 null STAT5B-24692510-EPITHELIUM-MOUSE-MAMMARY ChEA Transcription Factor Targets 2022 1.0 null HINFP JASPAR Predicted Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-P5-A733-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BLTP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17486 basolateral amygdaloid nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26629 Skin TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null outer CP in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.872925 hsa-miR-1343 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.139 N-terminal protein acetyltransferase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.112 LOVO DepMap CRISPR Gene Dependency 1.0 4.3982 Perturb_13306_KO_Hnf4a/Cdx2_SRP049189 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 GSE179974_3_v_1_carboplatin_mouse RummaGEO Drug Perturbation Signatures 1.0 null inner portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.52693 OPM2 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5402-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OVMANA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.09782 mammalian phenotype MPO Gene-Phenotype Associations 1.0 null DNAJC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13568 GSE157594_6_v_4_nicotinamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null TLX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4268 CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.878037 system process GO Biological Process Annotations 2015 1.0 null demonstrate GeneRIF Biological Term Annotations 1.0 null Uterine Carcinosarcoma_UCS_TCGA-NF-A5CP-01A-12R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_fibroblast of pulmonary artery_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CAMK2D Pathway Commons Protein-Protein Interactions 1.0 null ESR1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7608 CTCF_choroid plexus epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null small intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.08236 Henles loop TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.95 NCI-H1651 COSMIC Cell Line Gene Mutation Profiles 1.0 null Nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.533 r2 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.75614 ion transmembrane transporter activity GO Molecular Function Annotations 2015 1.0 null kidney HPA Tissue Gene Expression Profiles 1.0 1.03582 cerebralcortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.844832 SMC3 ENCODE Transcription Factor Targets 1.0 null Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.82613 sodium ion import across plasma membrane GO Biological Process Annotations 2025 1.0 null JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.3333 GSE201361_0_v_1_mpst_mouse RummaGEO Gene Perturbation Signatures 1.0 null TEAD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.2915 Nodulus (X), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42916 FLYWCH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.67985 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-SNU-5 COSMIC Cell Line Gene Mutation Profiles 1.0 null HOXB5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.5976 SSBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.71114 CTCF_HGPS cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HOXC8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0211 single-organism transport GO Biological Process Annotations 2015 1.0 null VSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.1868 MZ7-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null CTCF_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5913 WRNIP1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GRIN2A Pathway Commons Protein-Protein Interactions 1.0 null morphological abnormality of the gastrointestinal tract GWASdb SNP-Phenotype Associations 1.0 0.4008 STARD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.29109 GSE242290_3_v_10_glutathione_human RummaGEO Drug Perturbation Signatures 1.0 null ATF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.6771 YRDC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33436 H2BC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51152 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054117 DDX27 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.76455 r11 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50127 RAD21_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null single-multicellular organism process GO Biological Process Annotations 2015 1.0 null GSE216147_0_v_1_rbm20_mouse RummaGEO Gene Perturbation Signatures -1.0 null glucose metabolism disease GWASdb SNP-Disease Associations 1.0 0.248908