association	dataset	threshold value	standardized value
SLC44A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20295
INPP5K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04088
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.8566
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UACC257	DepMap CRISPR Gene Dependency	1.0	3.07744
hsa-miR-181d	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
HCC202	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57008
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19772
EXOSC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1316
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.3618
H3K36me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5882
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11703
OXTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05922
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17603
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.46625
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
GSE151494_8_v_3_nrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1456
GSE225141,GSE225143_2_v_3_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
EFM19	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4277
WSU-DLCL2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37538
TKKK	DepMap CRISPR Gene Dependency	1.0	4.18559
Perturb_5135_KO_Ythdc1_SRP251747	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.82328
H3C15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40166
TLR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14495
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	124.29
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10837
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
G2E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35286
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9094
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08972
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5695
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
WRAP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72278
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33065
GPX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34789
UMUC9	DepMap CRISPR Gene Dependency	1.0	2.44012
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3148
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41483
SNU620	CCLE Cell Line Gene CNV Profiles	1.0	1.54675
hsa-miR-3647-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00992
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6301
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.2963
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05999
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.21219
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.2935
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7827
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.85489
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3141
NOMO1	DepMap CRISPR Gene Dependency	1.0	3.34755
NFIX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04214
SEC61G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31311
GSE195568_1_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21455
SCS214	DepMap CRISPR Gene Dependency	1.0	3.38495
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7784
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
PRPF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41714
RMGI	DepMap CRISPR Gene Dependency	1.0	3.28467
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
SW1116	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68018
Perichondrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.882
hsa-miR-181a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE158320,GSE183351_2_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.921921
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.06871
H3K79me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TRRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18205
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.452
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3414
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.957577
H2BC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17712
ATG16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66705
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.5843
COQ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33787
CTNND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52557
NUMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71475
Hirschsprung's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.224
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
PTS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39462
EIF2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02647
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852251
ZNF395	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01544
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.444
ZNF676	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31028
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09616
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4109
MAGED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29309
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NFKB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5051
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.1648
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.843
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.99333
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3097
MM253	DepMap CRISPR Gene Dependency	1.0	2.70248
CHPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74856
CCDC43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97599
CHTOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16915
G59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53664
primary auditory cortex (core)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.996322
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6499
SQ1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09841
FERD3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04094
CDC45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51677
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.8297
BC3C	CCLE Cell Line Gene CNV Profiles	1.0	1.68152
GSE126621,GSE126920_1_v_0_dppa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.32768
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37538
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35293
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC70	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.2703
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.30337
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4939
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43262
GEM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39144
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2789
kidney	GTEx Tissue Gene Expression Profiles	1.0	0.904915
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.907152
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5737
AP2S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4929
GSE202603_1_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1528
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2501
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07339
TMEM127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28284
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2632
PMC8104016-hcg-12-e002353-s010.xlsx-mTHP1-LPS_30kb-Interacting_Gene_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
OCI-M2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20841
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25331
stomach	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20576
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5025
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8611
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4307	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962021
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
GSE143994_0_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50632
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CBLC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6736
ZNF80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21947
ASB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03766
496100320_PCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12775
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.63063
PLD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11707
GSE131649_6_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38569
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAS2R5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42325
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.2716
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.5556
NCIH211	CCLE Cell Line Gene CNV Profiles	1.0	2.82681
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23117
NCK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00906
BRD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50095
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22775
dorsal thalamus_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.897456
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.2417
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1731
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13202
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24897
CHD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73499
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.66231
FOSL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3289
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884037
GSE216274,GSE216292_4_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04984
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3826
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62304
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.932778
ANAPC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91092
ZFAND3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57956
TOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0421
MEF2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16369
CTV1DM	DepMap CRISPR Gene Dependency	1.0	10.5904
mammarygland.lact.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.01315
HDAC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42847
MM160113	DepMap CRISPR Gene Dependency	1.0	7.27756
C22orf23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20176
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.343
NBDY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67359
hsa-miR-145	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9685
hsa-miR-4680-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
EBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46144
DHX35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47534
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8002
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2015
CTAGE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46869
ZSWIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46811
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16516
CALU6	DepMap CRISPR Gene Dependency	1.0	3.27563
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
SP110	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17328
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33137
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.929198
SEMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90662
SHSY5Y	DepMap CRISPR Gene Dependency	1.0	3.00492
RNPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3886
PMC8567280-EMBR-22-e53014-s007.xlsx-Sheet1-Nearest_genes_to_BAZ2A-bound_C2-Enhancers_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
Megacolon	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7368
CDK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05474
BLMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4361
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20576
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06242
KCNK15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61626
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54823
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45041
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.985076
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88837
esophagus	HPA Tissue Protein Expression Profiles	1.0	1.77126
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5008
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17298
HCC2935	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.880067
ARFGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18218
INAFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68774
GSE162590_1_v_0_gsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.2511
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.969046
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9967
MRPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85999
CHST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28238
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.055
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.095
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26468
hsa-miR-148a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Perturb_10718_KO_Hck_SRP340501	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.41544
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	2.18636
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0016
PHLDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23461
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.32431
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7509
ING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62497
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.949842
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
COLO680N	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38248
RERFLCKJ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32396
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843856
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.860551
HUH1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45416
BEX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25916
NCIH2052	DepMap CRISPR Gene Dependency	1.0	2.90559
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9645
ZBTB8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63713
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.2189
COV504	CCLE Cell Line Gene CNV Profiles	-1.0	-3.20629
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC70	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59469
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.043
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05447
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Smad4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.955
NCI-H345	COSMIC Cell Line Gene CNV Profiles	1.0	2.14116
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14008
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2683
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.54431
Pancreas-pancreatic beta cell	Tabula Sapiens Gene-Cell Associations	1.0	0.926101
VPS72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0063
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05447
hippocampus (hippocampal formation)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.875352
PMC8507136-12935_2021_2224_MOESM5_ESM.xlsx-CREB1_upregulated_RRHO_list-RRHO_concordant_degree_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43082
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3076
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829916
TIPARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39556
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lyf-1	MotifMap Predicted Transcription Factor Targets	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50124
RIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53572
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9905
HCC2814	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75553
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6747
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.880564
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4539
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1458
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	1.09095
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41825
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0576
DNAAF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44703
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2157
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8744
NCIH1703	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3561
HCC38	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09597
MAT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71858
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.54591
EXOSC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25352
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.15688
Melanophore	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.265
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5198
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41109
GOLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00026
ZNF716	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36268
GSE248659_1_v_0_klf5_human	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.08807
LCLC97TM1	DepMap CRISPR Gene Dependency	1.0	3.64731
A3KAW	DepMap CRISPR Gene Dependency	1.0	2.0415
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.8566
TMEM240	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61675
PMC4728380-ncomms10153-s8.xlsx-MYC_binding_intensity_ALL-Unnamed_15_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54823
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.878294
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.912326
PPP6R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04306
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01869
COLO783	CCLE Cell Line Gene CNV Profiles	1.0	1.72084
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	1.29636
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC25A15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02575
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC366	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52534
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11019
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37538
H3K36me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6026
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843856
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3626
496100558_PCx_probable Alzheimer's disease_TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08644
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
CAKI1	DepMap CRISPR Gene Dependency	1.0	2.18027
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	1.0	3.68814
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7767
SMIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34218
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961188
hsa-miR-152	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
RAD9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27453
PFDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8485
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29098
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25336
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7352
Auditory vesicle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.071
HT144SKINFV1	DepMap CRISPR Gene Dependency	1.0	12.3491
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.5774
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39386
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999738
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.9856
PMC10123531-NIHMS1874945-supplement-Table_S7.xlsx-SOX17_BCAT_4TCFKO_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.28438
RNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22289
GSE151494_1_v_9_nrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151782_1_v_5_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44154
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37538
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829916
hsa-miR-4756-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.0102
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.26254
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01992
RCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22966
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	37.2
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.846
ESRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87661
Xanthophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.936
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6605
SW1271	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88697
HT29	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12599
HCC1428	CCLE Cell Line Gene CNV Profiles	-1.0	-2.16267
TCEAL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00343
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.75979
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829916
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.985076
hsa-miR-23a	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
FCGRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95623
TMEM147	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36035
GSE216273,GSE216292_14_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hindgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.89
LMCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01176
macrophage	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14428
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.4861
SNU1544	DepMap CRISPR Gene Dependency	1.0	10.8675
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.58701
ZNG1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36568
POLR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7009
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.807
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CERS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20304
OVCAR8	CCLE Cell Line Gene CNV Profiles	1.0	1.49907
SNU1105	DepMap CRISPR Gene Dependency	1.0	3.3699
HOXB5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5796
MGAT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98388
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.50653
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.68868
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1098
ZNF423	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38638
GSE239578_1_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908034
NTERA2CLD1	DepMap CRISPR Gene Dependency	1.0	3.38309
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829916
MEOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4274
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.910833
UBXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63879
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28503
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF761	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2474
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5353
GSE238005_5_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FBXO21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62149
TRIM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15602
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38569
SNU1327	DepMap CRISPR Gene Dependency	1.0	3.59621
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.3461
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01405
CLDND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02106
hsa-miR-3616-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
MACROH2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49511
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.57025
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE69869_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellum	HPA Tissue Protein Expression Profiles	1.0	0.920097
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0096
GSE129186,GSE129223_0_v_1_aicda_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTF3C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36185
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
496100462_PCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.5527
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.862742
GSE216043_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TPD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01025
SP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.04928
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0855
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.7942
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3306
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
D283MED	DepMap CRISPR Gene Dependency	1.0	5.97917
SS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92653
membrane part	GO Cellular Component Annotations 2015	1.0	null
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.833839
KML1	DepMap CRISPR Gene Dependency	1.0	2.80355
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.349
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37538
SBDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78682
TLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72953
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.3505
MSH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10009
TFB1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98331
STPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01521
496100339_HIP_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14846
GSE86507,GSE86509_4_v_8_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAL-72	COSMIC Cell Line Gene CNV Profiles	1.0	2.14116
GPRASP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83816
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20528
GSE220520_6_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2416
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.7702
hsa-miR-203	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
FARSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34618
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.843856
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.06127
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87114
COLO684	CCLE Cell Line Gene CNV Profiles	1.0	1.75427
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06358
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20513
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9241
RNASEH2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45887
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.870206
MOLM13	CCLE Cell Line Gene CNV Profiles	1.0	1.8395
DU4475	DepMap CRISPR Gene Dependency	1.0	2.93058
IZUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3566
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38569
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.97001
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.1948
BRIX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96868
HOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.376
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06654
ITGB3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38708
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7342
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8646
ZNF675	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38519
SNU761	DepMap CRISPR Gene Dependency	1.0	4.4259
PYDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26057
NUTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37265
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4502
ETAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37717
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4346
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01182
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28589
GSE166920_6_v_5_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF648	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14836
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7442
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0246
FDPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57522
ISL1-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
VCX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50396
SNU761	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33838
RPL34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94626
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9906
PPP1CC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38576
Waardenburg syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.474
Perturb_8069_KD_SFPQ_SRP281189	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.31151
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN2_n_EN2	Rummagene Transcription Factor Associations 2026	1.0	null
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37538
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6744
osteoclasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.98568
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.903395
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5128
PLEKHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59528
CLPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58101
HEC1B	DepMap CRISPR Gene Dependency	1.0	3.29477
MFAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23126
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936239
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.991563
PHOX2B-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE96777,GSE96778_1_v_0_zbtb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HT144SKINFV2	DepMap CRISPR Gene Dependency	1.0	2.31954
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0678
Octamer	MotifMap Predicted Transcription Factor Targets	1.0	null
AIFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3357
GSPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16225
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_downregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.2932
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9837
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SNU182	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3888
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.880564
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.1525
PRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08909
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE100316_7_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN1_n_EN1	Rummagene Transcription Factor Associations 2026	1.0	null
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.6894
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.9534
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00528
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.63
hsa-miR-148b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.3038
LTB4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14772
hsa-miR-23b	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7104
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.846286
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.80606
SSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08824
DGCR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7251
LY6G5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17854
PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
EPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24769
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.946787
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
ALDH6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6401
CHRNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19214
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62251
CCNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51545
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PYCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57413
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_13052_KO_Il17a_SRP268747	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.86229
RTRAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38903
GABRA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47875
ANXA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66846
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9684
MEG01	CCLE Cell Line Gene CNV Profiles	1.0	1.67644
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3086
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45093
SMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32979
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13379
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6276
SON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03847
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7399
H3K36me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38517
Plasma membrane-derived chromatophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.461
hsa-miR-3127-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Tal-1beta:E47	MotifMap Predicted Transcription Factor Targets	1.0	null
TRIM56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66079
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88554
NDUFA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5554
MCRIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36279
GSE148252_0_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3782
GSE242199_6_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RPL36A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96495
SOGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66905
CXCL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30781
TRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34052
GSE216043_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
APOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70887
SW 982	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.958529
GATA3-30127528-BE2C-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3891
CIAO2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12523
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0066
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3889
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07933
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6684084-pntd.0007589.s007.xlsx-Sky_Blue_Module-NFYA_NFYA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150895,GSE150896_0_v_1_kif15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68922
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6064
ARL16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54307
H357	DepMap CRISPR Gene Dependency	1.0	5.69463
CPSF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39563
ATP2C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63439
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857394
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11015
APP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12263
ASF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50292
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7846
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.2322
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03988
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37538
TIMM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29528
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.22897
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OTUD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42318
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-fromNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216043_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.21451
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828967
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5744
GDM1	CCLE Cell Line Gene CNV Profiles	1.0	1.40857
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0162
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35354
GSE186440,GSE186443_3_v_7_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GJC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3878
GI1	CCLE Cell Line Gene CNV Profiles	1.0	1.53043
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
cervix uteri	GTEx Tissue Gene Expression Profiles	-1.0	-1.46607
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.982368
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	73.9846
hsa-miR-573	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
hsa-miR-3618	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE180185_4_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.93352
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.83913
CDK5RAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50112
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909842
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPM1K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10884
TFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44266
ACSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1912
thiamine_rattus norvegicus_gpl2896_gse19292	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57467
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4254
H3K36me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65557
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.863119
MEL270	DepMap CRISPR Gene Dependency	1.0	2.45172
GRHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02798
GSE196540,GSE196542_4_v_5_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KCL22	CCLE Cell Line Gene CNV Profiles	1.0	2.06098
ECC10	CCLE Cell Line Gene CNV Profiles	1.0	1.6394
BTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61783
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.996319
ARL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34271
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.862742
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14668
ANKS1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24038
PSMG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60783
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28589
GLMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58443
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.65391
ESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65468
UGGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10177
DMS53	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47206
POLR2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96443
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.05592
PRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82182
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9515
RPS4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60627
GPKOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03336
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5B-Up_H3K4me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1333
CIAO2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04855
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.845781
hsa-miR-375	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
EFCAB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90257
kidney	HPA Tissue Gene Expression Profiles	1.0	1.02142
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.965706
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CNN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46307
SKN3	DepMap CRISPR Gene Dependency	1.0	2.30676
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.04662
SW1417	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79547
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0937
EIF3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00877
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.734
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.415
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52639
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
ADAMTS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69721
GET4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04141
RSL24D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55011
hsa-miR-4328	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
EIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88651
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.66926
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62742
DEDD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08056
TRAPPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27355
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12619835-41467_2025_66007_MOESM12_ESM.xlsx-KLF5_activated_H3K27ac_T3M4-Nearest_Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
H3K36me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02571
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9448
F2RL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32754
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NDUFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06415
SKNMC	CCLE Cell Line Gene CNV Profiles	1.0	2.36526
GPR160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.52048
CCER2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06835
Waardenburg syndrome type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.299
C19orf53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50049
SW982	DepMap CRISPR Gene Dependency	1.0	3.20605
IFI27L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56015
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.913
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.03356
Inner chondrogenic layer of perichondrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.042
CENPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59339
MED17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17638
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6013
hsa-miR-3163	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
EMILIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21381
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.966591
SYNM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64669
MRPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41931
GSE148252_0_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.68922
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962021
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6481
ZNF724	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01546
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
uterus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.904442
hsa-miR-181b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
TYK-NU.CP-R	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88554
GSE187006_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9809
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.935742
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NEDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19907
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5905
Opioid abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.62
ERCC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77503
LYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29617
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.57299
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38569
PCDHB15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71108
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5237
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0917
MTREX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1884
RBM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04213
FAM118A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.07439
RPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48794
open-angle glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
ALDH3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39148
JHUEM1	DepMap CRISPR Gene Dependency	1.0	2.72734
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TE441T	CCLE Cell Line Gene CNV Profiles	1.0	1.48387
H3K36me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25609
GSE101239_5_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
PGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38965
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08222
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.42832
chr8_30631171_C_A_b38	GTEx eQTL 2025	1.0	1.61589
DANG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64895
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.8956
GSE138863_2_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_11_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.68783
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1572
LOUNH91	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49151
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF275	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66824
hsa-miR-23c	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8417
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15712
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1185
Hand1::Tcf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4828
CACNG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34341
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ER_ZNF_GATA3-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TAF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24694
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148066,GSE157787_9_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RILP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11794
striatum_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26572
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.829916
GSE201381_0_v_1_bhlhe22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5295
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BTAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39635
Hoxa11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5945
CHRNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06595
LAMA84	CCLE Cell Line Gene CNV Profiles	1.0	1.48322
hsa-miR-511	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
SLC24A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11762
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.856187
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OCIMY5	DepMap CRISPR Gene Dependency	1.0	2.52582
Mafb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8408
HS695T	DepMap CRISPR Gene Dependency	1.0	6.50993
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-T3M4_KLF5_activated_H3K27ac_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
SNU475	DepMap CRISPR Gene Dependency	1.0	3.56574
UMRC3	DepMap CRISPR Gene Dependency	1.0	2.07119
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.4497
GSE216043_11_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pancreas-pancreatic delta cell	Tabula Sapiens Gene-Cell Associations	1.0	0.14919
MLF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0129
Myf	MotifMap Predicted Transcription Factor Targets	1.0	null
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.757
SNAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2409
PPP3CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99086
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03159
PEX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71006
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9774
TBL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12233
GSE218580_1_v_4_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SPEG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82182
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58117
CCDC174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35117
H3K36me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8151
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.55515
SNU13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8138
BT549	CCLE Cell Line Gene CNV Profiles	1.0	1.86706
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57
TRAPPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42262
SNU61	CCLE Cell Line Gene CNV Profiles	-1.0	-1.75226
hsa-miR-3941	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.3836
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATP13A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0805
Glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.596
EN	DepMap CRISPR Gene Dependency	1.0	2.07217
brain	HPA Tissue Gene Expression Profiles	1.0	2.10073
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF548	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24361
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5277
GGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14095
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.635
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50274
ZWINT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90878
GSE165579_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Chondrogenic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.042
IMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2614
TGFBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19433
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45093
SMAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46874
TMEM170B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83099
H3K36me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RIGI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37906
ALX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61578
GSE196104,GSE196106_3_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12909
GATA1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MDAMB361	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66771
UBE2L6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68787
hsa-miR-558	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
CREB3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22881
hsa-miR-181c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
ZBTB26	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7093
TAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97217
MACO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24527
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5062
ARRDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39122
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2025
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	3.39292
DiGeorge syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
SKCO1	CCLE Cell Line Gene CNV Profiles	1.0	2.67811
hsa-miR-4262	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.4004
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.17661
SERINC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17317
ZNF684	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1278
NCI-H1155	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37538
MRGPRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20147
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05624
OVMIU	DepMap CRISPR Gene Dependency	1.0	2.32139
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.988666
cellular_component	GO Cellular Component Annotations 2015	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.932778
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.98913
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831901
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.86
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32954
hsa-miR-4709-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
SLC25A25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27493
NDUFAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52981
SNU182	DepMap CRISPR Gene Dependency	1.0	4.81031
THP1	CCLE Cell Line Gene CNV Profiles	1.0	1.44252
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01405
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.988476
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4742
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null