association	dataset	threshold value	standardized value
JMY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63806
GSE165647_2_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Autism spectrum disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.908
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_9_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Arthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.434
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
RSF complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.512
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2602
MAPKAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40465
RPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82686
A1BG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39684
THOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.65145
GTEx Heart 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	8.06801
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3403
Polysomal ribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.029
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6918
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9942
ATF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11026
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9494
EBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2595
SOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37702
GSE221577_1_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE72895,GSE72896_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
TXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14546
GSE176008_0_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Nearest_Ensembl_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.24994
PMC6870463-Table_7.xlsx-Family_H_LPS-LPS_treatment_of_BMDMs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
AKAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24795
Cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.935
STAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55882
CLCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73809
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.006
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.7171
SINHCAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15491
Chondrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.022
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0439
GSE162384_1_v_0_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0718
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59842
GSE201668_0_v_1_ncor2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226544_1_v_0_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.37
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TIPARP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07875
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SOGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07672
GSE116299_4_v_3_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7914369-thnov11p3676s2.xls-BPTF-KOvsCtrl-AccID_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
GSE242083,GSE242098_3_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100637_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00325
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1914
PMC7863452-12920_2021_883_MOESM5_ESM.xls-SRG_13_GE2-HCC_vs_17NT-GENENAME_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Intervertebral disc	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.068
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8482
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5576
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71087
GSE195568_3_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
External side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.505
GSE84678,GSE93902_3_v_2_bcl11b_human	RummaGEO Gene Perturbation Signatures	1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.085
GSE165647_6_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9745835-supp_079195.122_Supplemental_Table_1.xlsx-ADAR-KD-Gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-2q37_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
MUC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19081
ILF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58382
TRNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80685
SH3BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06648
AVPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80393
GSE135705_5_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GABRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38282
PMC11602576-mmc11.xlsx-ST12-Table_S12_Output_of_mash_model_of_milk_and_GTEx_eQTL_effects_Related_to_Figure_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11979751-table_s2_markers_elad055.xlsx-Melanoma_state_markers-AP2_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
Melancholic depression	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.37
chr2_232887929_A_T_b38	GTEx eQTL 2025	1.0	1.41941
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3676
CCZ1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68438
EXOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70117
Osteoarthritis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.741
ASCL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37271
PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
THAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0113
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DKC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62625
PMC12230629-BRB3-15-e70664-s002.xlsx-Supplementary_Table_6-Supplementary_Table_6A_Results_of_single-cell_eQTL_MR_analysis_for_causal_effects_of_genes_on_Childhood_ADHD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
chr2_232874968_T_C_b38	GTEx eQTL 2025	1.0	3.19923
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.19188
GSE221577_4_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145915_0_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Tic disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.424
ZNF180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15644
LEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35925
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.424
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2755
ZNF614	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20103
GSE189859,GSE189861_0_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.554
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8456
GSE185519_3_v_0_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE248501_1_v_0_mst1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220520_1_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Attention deficit hyperactivity disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.49
Major depressive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.37
496100549_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.54221
VPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04699
ZYG11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09133
BATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9185
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7317
RPLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06765
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE185519_4_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4935
DBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75417
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.308
Small Intestine - Terminal Ileum	GTEx Tissue Gene Expression Profiles 2023	1.0	1.07685
DYNC1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57596
PMC8200296-LSA-2020-00928_TableS2.xlsx-table_s2_DEGs_log2foldchange_0-Table_S2_List_of_DEGs_induced_by_YY1_knockdown_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
PFDN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04363
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7336
EIF2B4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69131
Tenocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.443
HNRNPCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25635
EIF3I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28445
GSE143782_3_v_11_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Endochondral bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.203
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6957
APOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69744
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0975
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1943
GSE128730_3_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149359_2_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sternal cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
HCE cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.621
MAP4K5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31128
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180185_4_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ADAMTSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2443
FSTL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35888
skeletal system development	GO Biological Process Annotations 2025	1.0	null
PMC10864182-41588_2023_1596_MOESM4_ESM.xlsx-ST12_Significant_Genes_combine-Supplementary_Table_12_Genes_prioritisation_combining_FUMA_MAGMA_Hi-C_MAGMA_and_TWAS_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8127
Nitrate reductase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.064
NarGHI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.223
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Up_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.20024
GSE118617,GSE118619_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202310_1_v_0_ube3d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_4_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101767_1_v_0_wdr11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
WBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59387
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149901_3_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
Anorexia nervosa, attention-deficit/hyperactivity disorder, autism spectrum disorder, bipolar disorder, major depression, obsessive-compulsive disorder, schizophrenia, or Tourette syndrome (pleiotropy)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0699
MCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01003
496100615_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36786
TEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44558
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12230629-BRB3-15-e70664-s002.xlsx-Supplementary_Table_7-Supplementary_Table_7A_Results_of_single-cell_eQTL_MR_analysis_for_causal_effects_of_genes_on_late-diagnosed_ADHD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ZCRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38369
TEPSIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73704
BARD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51915
GSE193258,GSE193259_2_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16663
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	53.5671
GSE171572_5_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
Inner chondrogenic layer of perichondrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.808
RNA polymerase II termination complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.527
LMCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08796
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6786
GSE185944_2_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE151829,GSE151831_3_v_0_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bipolar disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
PMC6962646-mmc2.xlsx-StemCell_Genesets_2018-NANOG_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
TEKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0393
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
ERVK3-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14587
Bone disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.406
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9004
SOCS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36897
BNIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3401
JDP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7135
GSE158834_10_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
POT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10205
Sclerotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.692
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.3282
GSE214335_1_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
TADA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07463
Osteophyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.954
GSE156907,GSE160237_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
col10	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.795
NHLRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09181
Metatropic dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
496100626_FWM_no dementia_TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.78697
GSE228106_3_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1704
GSE215461_0_v_1_topotecan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28883
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1697
496100620_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.02825
YTHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42542
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE148200_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	1.95344
PMC8567280-EMBR-22-e53014-s007.xlsx-Sheet1-Nearest_genes_to_BAZ2A-bound_C2-Enhancers_BAZ2A	Rummagene Transcription Factor Associations 2026	1.0	null
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.6676
PMC7161353-supp_073353.119_Supplemental_Tab_S8.xlsx-LUAD_HRGs_correlation_to_MBNL2-gene_name_MBNL2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GAPVD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42448
GSE131649_4_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TFPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37175
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.529
TIMM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15935
PMC4823830-ncomms11171-s4.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12230629-BRB3-15-e70664-s002.xlsx-Supplementary_Table_8-Supplementary_Table_8A_Results_of_single-cell_eQTL_MR_analysis_for_causal_effects_of_genes_on_persistent_ADHD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE74490_0_v_1_triptolide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE111247_2_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0851
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
LSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18706
SSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64293
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9257
SRSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38219
Articular cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.832
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab8_TRIM11-KD-up_genes-Table_8_Up-regulated_genes_in_TRIM11-KD_TRIM11-KD1_Control_overlap_TRIM11-KD2_Control_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MUC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25612
GSE84462,GSE84762_0_v_1_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NOC3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01611
GSE111247_11_v_9_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHORDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.808
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5738693-12944_2017_641_MOESM2_ESM.xls-FPP_vs_Control-Unnamed_2_MSX2	Rummagene Transcription Factor Associations 2026	1.0	null
ADM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34289
GSE207582_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
ACCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32044
WDR33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02544
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RFWD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1432
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26545
ZNF592	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13878
GSE173810_4_v_6_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WDR24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28487
Perichondrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.557
Prostate adenocarcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
GSE171572_0_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5550424-41467_2017_212_MOESM4_ESM.xlsx-Hematlas-Genesets-NANOG_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
CREB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07269
RPIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9783
496100628_FWM_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.18719
TSPAN17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60282
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7552
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.321
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_2_AP2_Up_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_10_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10185556-41467_2023_38439_MOESM3_ESM.xlsx-ST19_MR_results-nearest_gene_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SLAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41373
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8953
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
ANKMY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75607
GSE116299_6_v_5_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver bud hepatic cell_Liver_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tibial cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
PRKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32761
GSE146982_3_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6733
GSE221577_3_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Gilles de la Tourette syndrome	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.424
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6613
chr2_232880623_G_C_b38	GTEx eQTL 2025	1.0	1.23469
MCCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13338
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Specific developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.424
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.052
TPCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28787
GSE147366_1_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_10_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
E4F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27597
496100629_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.6436
Corneal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.51
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE96093_1_v_0_abca1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12230629-BRB3-15-e70664-s002.xlsx-Supplementary_Table_3-Supplementary_Table_3_Results_of_single-cell_eQTL_MR_analysis_for_causal_effects_of_genes_on_ADHD_significant_association_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE232631_0_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr2_232887666_A_T_b38	GTEx eQTL 2025	1.0	5.20565
496100518_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.92541
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.771
MRPL35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05342
PMC9882185-media-4.xlsx-Neuron_KD-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12230629-BRB3-15-e70664-s002.xlsx-Supplementary_Table_4-Supplementary_Table_4A_Results_of_heterogeneity_test_of_single-cell_eQTL_MR_analysis_ADHD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Htk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.637
Developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.424
PPIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28298
GSE146982_4_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7863452-12920_2021_883_MOESM2_ESM.xls-SRG_23_HCC_vs_17_NT-GENENAME_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
SAPCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22957
ANP32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90955
PMC6870463-Table_7.xlsx-Family_H_No_LPS-Untreated_BMDMs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135352_0_v_1_napabucasin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.74741
VMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38072
GSE158834_10_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
PHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44215
TMEM185A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33284
cartilage development	GO Biological Process Annotations 2025	1.0	null
GSE188382_2_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7161353-supp_073353.119_Supplemental_Tab_S8.xlsx-BRCA_HRGs_correlation_to_MBNL2-gene_name_MBNL2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10928104-41419_2024_6576_MOESM4_ESM.xlsx-S14-MYBL2_targets_MYBL2	Rummagene Transcription Factor Associations 2026	1.0	null
Np	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.407
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70118
NPIPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0109
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216326_2_v_0_sulodexide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Hypotrichosis 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.699
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE221577_3_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4823830-ncomms11171-s3.xlsx-high_in_shRNA_GATA3-GeneSymbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Cognitive disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.37
GSE111061_1_v_0_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6934839-41598_2019_56277_MOESM2_ESM.xlsx-ONECUT2_DOWN-Gene_Symbol_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
TPRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24618
Pervasive developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.908
MTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71889
OTULINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74485
PMC12230629-BRB3-15-e70664-s002.xlsx-Supplementary_Table_5-Supplementary_Table_5A_Results_of_bulk_tissue_eQTL_MR_analysis_for_causal_effects_of_genes_on_ADHD_significant_association_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146982_4_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03026
GSE76425_0_v_5_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE180789_1_v_0_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Muscle - Skeletal	GTEx Tissue Gene Expression Profiles 2023	1.0	5.62251
GSE63857_3_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.96986
Pelvic fin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.252
PRRC2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43409
GSE213228_4_v_0_irak2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-Gene_Name_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
NAA50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28522
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76733
WFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08377
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
GTF2A1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37419
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Annulus fibrosus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.325
Caudate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Classical_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Ahr::Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.625
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC3712200-584604.f1.pdf-6-MBNL2_MBNL2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11336098-41598_2024_70235_MOESM1_ESM.pdf-974-SMAD3_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149000_2_v_0_cyp3a5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1699
YARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32592
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.6481
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.9036
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.428
GSE135352_2_v_3_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Bone marrow stromal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.963
GSE143944_2_v_3_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE218378_1_v_0_pbx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bone inflammation disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.427
chr2_232869373_G_A_b38	GTEx eQTL 2025	1.0	3.24811
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.751
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Chondrosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.903
connective tissue development	GO Biological Process Annotations 2025	1.0	null
Plasma membrane respirasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.213
chr2_232870999_G_A_b38	GTEx eQTL 2025	1.0	3.56552
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
KLC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04948
GSE192771_2_v_1_mt1g_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RASD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06962
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4442
GSE146982_4_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53688
GSE236504,GSE236505_0_v_1_atmin_human	RummaGEO Gene Perturbation Signatures	1.0	null
RUFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17783
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Chondrogenic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.808
DARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19175
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	1.17658
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE210093_0_v_2_taf15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE232631_0_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05225
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9168
PARP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94913
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.735
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE128076_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239844_8_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.378
LONRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32504
PMC5503627-oncotarget-08-39497-s003.xlsx-hypo_in_shUHRF1_KD-Unnamed_7_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE116299_6_v_1_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE102870_3_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PYGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12395
GSE228430_1_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE232631_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EBNA1BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64294
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100642_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.50392
GSE218580_1_v_2_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22385
PMC7532671-thnov10p10957s2.xlsx-Table_S6A-Table_S6A_Differentially_expressed_genes_DEGs_in_DDX5_KD_versus_WT_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9478
PMC7378211-41598_2020_69015_MOESM3_ESM.xlsx-EWS-WT1_rep1_testp-7_annotatedp-ID_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
SPDYE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13171
Epiphyseal growth plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.659
YTHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88103
GSE192771_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IFI27L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27846
Hepatoma ascites cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
GSE135514_8_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SACM1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15189
REST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25319
GSE147240_3_v_4_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE151090_0_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CLN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61648
PCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45199
ZNF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91148
PMC11196642-41419_2024_6838_MOESM5_ESM.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_expressed_genes_in_RNA-seq_between_MCF7_SMAD4-KO_and_parental_groups_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Mccoy	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.504
GSE77007_0_v_1_med23_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217452_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11932929-41388_2024_3264_MOESM4_ESM.xlsx-p_0_05_FC_0_5_n_675-Differentially_expressed_genes_in_MCF7_AR-isolated_BCSCs_after_4_days_GSK591_500nM_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-ENSEMBL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11214527-mmc5.xlsx-POU5F1-gene_POU5F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9061835-41523_2022_425_MOESM1_ESM.xlsx-S3_Differential_GEX-Table-S3_Differential_expression_analysis_results_for_SOX10-high_versus_SOX10-low_TNBCs_from_the_TGCA_and_METABRIC_expression_datasets_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_6_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
496100471_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19432
TRAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07602
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35792
TOPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19597
GSE168401_2_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE185944_2_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54906
KRT10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50735
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.334
PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
NoRC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.066
NKG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62527
PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
chr2_232870983_C_T_b38	GTEx eQTL 2025	1.0	2.98923
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4688
POLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00035
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6727
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Chondrocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.002
GSE181521_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9630632-Table1.XLSX-diff_exp_genes-Group_1_vs_2_AND_Group_2_vs_3_NOT_Group_1_vs_3_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
MDA-PCa-2b cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.866
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2855
GSE165647_5_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FAM72D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27223
PCDHB16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28288
GSE202434,GSE202438_9_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
LRSAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35861
Fibrochondrogenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.126
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
RNF216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1044
ATDC-5 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.626
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32981
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68862
OSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63542
Osteochondrodysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.405
Meniscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.058
GSE203329_0_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199092_3_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171837_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE109140_2_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE146982_4_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.424
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6476
PMC11979751-table_s2_markers_elad055.xlsx-Melanoma_GSEA_state_markers-AP2_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
HAUS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48106
SSBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88456
PMC11653668-ADVS-11-2400133-s005.pdf-8-THAP11_THAP11	Rummagene Transcription Factor Associations 2026	1.0	null
ABCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13843
PET100	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10244
GSE232631_4_v_3_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218060_7_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9904760-elife-79363-supp2.xlsx-MDS1-Gene_MECOM	Rummagene Transcription Factor Associations 2026	1.0	null
Limb bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.506
GGTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16413
PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-196-PRDM15_PRDM15	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11758349-11130_2024_1262_MOESM1_ESM.docx-4-RFXDC2_RFX7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE241701_4_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.419
Cartilage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.387
PARL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64439
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOSB::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5457
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.8236
DPYSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1632
Chondroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.169
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3957
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1647
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1563
GSE216274,GSE216292_4_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Autism spectrum disorder or schizophrenia	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9385
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
OLFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05065
BRD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41802
Sperm head-tail coupling apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.43
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0634
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9633
GSE128076_2_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	1.0	null
PITX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4526
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.726
GSE227592_4_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Brachyolmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.103
PMC9296003-supp_gad.348982.121_Supplementary_Table_S1.xlsx-PeakCallEPC1-PHF1_H3K27me3_k562-SYMBOL_PHF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_7_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66768
PMC11058205-42003_2024_6202_MOESM6_ESM.xlsx-Data3a_DirectGene_CEBPA-Data3a_Genes_directly_regulated_by_CEBPA_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
TRMT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27532
GSE198982,GSE198986_1_v_2_daunorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nucleus pulposus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.172
EXT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0411
Bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4853
GSE146982_3_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUPT16H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76573
GSE186005_1_v_2_klf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE197555_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_9_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NTMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0139
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9329
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8869
EEF1E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06223
Epiphysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.549
GSE240344_1_v_0_uxs1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2033
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171177,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE136742,GSE136744_0_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
HSPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66477
chr2_232866534_G_C_b38	GTEx eQTL 2025	1.0	1.44905
GSE144443_0_v_6_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOSL2::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6069
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.07454
BATF::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6943
GSE227592_0_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE127970_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100641_PCx_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.39678
Matrilin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.79
TRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60665
DCXR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48923
Interdigit	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
CHRNA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.705
GSE121824,GSE121826_0_v_6_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
HuH-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.857
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7951
GSE111247_11_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLEKHJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03258
RARB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61004
GSE141624_1_v_7_cocaine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50355
GSE183251_1_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24424
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9564215-pnas.2203480119.sd02.xlsx-OVCAR-5_SCD_KD_cultured_in_low-hgnc_symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ARSI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06699
GSE202434,GSE202438_10_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BATF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5834
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE167956_4_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120370_0_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Mood disorder	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.37
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_7_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Long bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.207
RPP38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47311
MYBL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2886
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135350_2_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6548
GSE109140_0_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE141667_3_v_10_cocaine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HTC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.001
SSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06124
MRNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41711
CNPY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42252
GSE171179,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
C3H10T1/2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.261