association	dataset	threshold value	standardized value
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TW-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BEN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81203
Adrenocortical carcinoma_ACC_TCGA-OR-A5JZ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CASTOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17335
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M5-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
estradiol-6957	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A735-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
isolation	GeneRIF Biological Term Annotations	1.0	null
NCIH727	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87266
reports	GeneRIF Biological Term Annotations	1.0	null
AM-38	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.53061
Mesothelioma_MESO_TCGA-MQ-A4LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MON1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0845
cellular_component	GO Cellular Component Annotations 2015	1.0	null
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02679
S100A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76555
iohexol-4643	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10307
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48785
Posterior uveal melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
C11orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17346
Brain Lower Grade Glioma_LGG_TCGA-DU-6392-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.60579
SK-MEL-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962567
GM97	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.84206
controls	GeneRIF Biological Term Annotations	1.0	null
RFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37717
celastrol-887	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A669-02A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epididymis	HPA Tissue Protein Expression Profiles	-1.0	-1.12486
sodium phenylbutyrate-407	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
spiradoline-3818	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Mesothelioma_MESO_TCGA-LK-A4O7-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TestisGermCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.11423
Sensory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
trimethoprim-3678	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF126	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42197
GM133	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.857226
GSK3B_knockdown_202_GDS4305	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.59591
MKN45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4863
benzathine benzylpenicillin-4140	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6914-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4905481-oncotarget-07-11397-s003.xlsx-CtBP2_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PGR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65799
SK-MEL-3	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.53061
pioglitazone-7088	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
flumetasone-3712	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNU-475	GDSC Cell Line Gene Expression Profiles	1.0	1.51515
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.5
FU97	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3666
TIGD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15069
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65541
DMS454	CCLE Cell Line Gene CNV Profiles	-1.0	-2.3514
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Metastatic Intraocular Melanoma	DisGeNET Gene-Disease Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-46-3769-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prestwick-685-3683	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
fluvoxamine-3995	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NT5DC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94291
OV7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85055
17690704-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
MIF_DEPLETION_GDS3626_95_human_HEK293 kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.993117
PRAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4892
IPMK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28509
Uveal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.456
SPANX family protein	InterPro Predicted Protein Domain Annotations	1.0	null
LN18	BioGPS Cell Line Gene Expression Profiles	1.0	1.01948
pilocarpine-5341	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
lung	HPA Tissue Protein Expression Profiles	1.0	0.927101
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AM38	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59447
sirolimus-1059	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SK-LMS-1	GDSC Cell Line Gene Expression Profiles	1.0	2.47577
chlorpromazine-1055	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
epidermis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
LPAR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12184
CD105+_Endothelial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.892486
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7X0-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8636-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
CDKN2AIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40793
LU-99A	GDSC Cell Line Gene Expression Profiles	1.0	1.46574
naftidrofuryl-5287	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8585-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OGFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80339
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0721
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
NCIH1781	CCLE Cell Line Gene CNV Profiles	1.0	1.4824
Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBQLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56421
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.826499
PMC10335698-pone.0285806.s007.xlsx-DMKN-shRNA_KD_Vs_ShSrc-Unnamed_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SKM-1	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.53061
Morgagni cataract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
STPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29764
Melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.629
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
fludroxycortide-3679	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC6639357-41467_2019_11150_MOESM4_ESM.xlsx-SupTab1_Activated_genes_diffex-Supplementary_Data_1_Fold_change_and_p-value_of_all_activated_protein_coding_genes_upon_DNMT1-KO_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
SNU601	CCLE Cell Line Gene CNV Profiles	1.0	1.38488
TYK-nu	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51916
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RN-01A-12R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
melanoma	GeneRIF Biological Term Annotations	1.0	null
PNU-0230031-3732	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KNS-42	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42169
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21495
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.34252
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
TestisSeminiferousTubule	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.21067
PADI4-21655091-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A76O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824067
Skin melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MN-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOP62	BioGPS Cell Line Gene Expression Profiles	1.0	0.866889
tolazamide-4003	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
variability	GeneRIF Biological Term Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5029-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LMTK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.55859
GOLGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82395
FADU	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37459
SPG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49518
LATS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05902
CD4+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.73151
PIAS1_KD_GSE44024_133_human_breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
POP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30632
statistical	GeneRIF Biological Term Annotations	1.0	null
MYO1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76691
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.15821
Adrenocortical carcinoma_ACC_TCGA-OR-A5JS-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epidermal cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GCT	GDSC Cell Line Gene Expression Profiles	1.0	1.64487
CISD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78149
phthalylsulfathiazole-5249	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
zidovudine-5333	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.878927
SH3BGRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54596
metabolic	GAD High Level Gene-Disease Associations	1.0	0.293278
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A67A-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CNOT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06211
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039293
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85055
Mesothelioma_MESO_TCGA-NQ-A57I-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOXIMVI	GDSC Cell Line Gene Expression Profiles	1.0	1.64991
Infertility, Male	HuGE Navigator Gene-Phenotype Associations	1.0	null
carbamazepine-952	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAGI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58319
NCIH929	CCLE Cell Line Gene CNV Profiles	1.0	2.59998
Pancreatic adenocarcinoma_PAAD_TCGA-RB-A7B8-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A819-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-US-A779-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sample	GeneRIF Biological Term Annotations	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2821
clomifene-6648	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
alpha-ergocryptine-3817	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COLO-679	GDSC Cell Line Gene Expression Profiles	-1.0	-1.49616
felodipine-965	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03802
UBE2Q2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40836
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
ANP32A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80614
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11079
ioversol-5326	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
C19orf12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77718
SH4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33233
oxetacaine-4246	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
difference	GeneRIF Biological Term Annotations	1.0	null
spanxc	GeneRIF Biological Term Annotations	1.0	null
SUM159PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.02231
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.795697
C14orf132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60747
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.45502
KIDINS220	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24184
propranolol-3059	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CAPAN-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91033
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848358
PPP2R2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16122
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61O-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAY-10397-7087	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EFO21	CCLE Cell Line Gene CNV Profiles	1.0	1.45703
SW900	CCLE Cell Line Gene CNV Profiles	1.0	1.34444
ALS2CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71627
JHOS-4	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.53061
Uveal Melanoma	DisGeNET Gene-Disease Associations	1.0	null
PLA2G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94368
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
genetic	GeneRIF Biological Term Annotations	1.0	null
GPI-PLD_OE_GDS2049_176_human_Hepatoma HepG2 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
NOTCH_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
calcium folinate-3703	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26527
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
Daoy	GDSC Cell Line Gene Expression Profiles	1.0	1.72946
Prostate adenocarcinoma_PRAD_TCGA-EJ-5494-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
2,6-dimethylpiperidine-3806	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
isoconazole-7211	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Synovium cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
COR-L88	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.53061
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19184
ZDHHC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68156
GATA3_Ectopic expression_GDS4080_622_human_Basal Breast Cancer Cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
gata3_21892208_mda_mb_231_gof_human_gpl570_gds4080	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.56088
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.56369
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.63619
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.25189
SR-95639A-6632	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COLO-684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAF1_overexpression_220_GSE42964	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.68761
TPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71709
smooth muscle	HPA Tissue Protein Expression Profiles	1.0	1.61187
LOU-NH91	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04149
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7890-01A-12R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CZ-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.62327
demecolcine-1103	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
metaraminol-3669	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-0.70726
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
Brain Lower Grade Glioma_LGG_TCGA-DB-A4X9-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848358
T3M10	CCLE Cell Line Gene CNV Profiles	1.0	1.41107
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6348-11A-01R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vagina	GTEx Tissue Gene Expression Profiles	-1.0	-0.887209
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
IDH3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12572
desoxycortone-5357	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-K7-AAU7-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_POU5F1_20526341	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
ANXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08489
PLAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80031
fluphenazine-1075	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UO31	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.983
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55816
lithocholic acid-3816	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
akap3	GeneRIF Biological Term Annotations	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22294
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.891586
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3736
cefepime-6159	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
troleandomycin-1465	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SK-MES-1	GDSC Cell Line Gene Expression Profiles	1.0	2.27877
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
Brain Lower Grade Glioma_LGG_TCGA-DB-A75L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08233
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36632
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.12486
HCC1419	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.769432
sera	GeneRIF Biological Term Annotations	1.0	null
Tumor Progression	DisGeNET Gene-Phenotype Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7299-01A-21R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A3KAW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44561
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50926
clemizole-3672	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U9-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-GJ-A9DB-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040141
levonorgestrel-3708	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960386
C32	GDSC Cell Line Gene Expression Profiles	-1.0	-1.664
ATP2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.50634
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-1.12486
GPR173	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59446
CD14+_Monocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.931358
STK24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53897
Azoospermia	HuGE Navigator Gene-Phenotype Associations	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
HS695T	CCLE Cell Line Gene CNV Profiles	1.0	2.09862
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T0-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
OVCAR4	CCLE Cell Line Gene CNV Profiles	1.0	1.77582
particular	GeneRIF Biological Term Annotations	1.0	null
BNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78836
Uveal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
skin cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Bipolar Disorder_frontal cortex_GSE5389	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.73982
gramine-3999	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
Synovial sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.142
ZNF770	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52011
DU-145	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51792
PSMC3IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04533
subjects	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5374-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3683358-NIHMS463907-supplement-2.pdf-5-EPAS1_EPAS1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7542-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
seminal vesicle	HPA Tissue Protein Expression Profiles	-1.0	-1.12486
DMS114	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5621
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RW-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HUPT4	CCLE Cell Line Gene CNV Profiles	1.0	1.80672
iPS-20b Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.87232
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39547
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7LX-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PI-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.97682
LARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04288
POMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39897
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fluorouracil	CTD Gene-Chemical Interactions	1.0	null
UterusCorpus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.931901
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
hepatocellular	GeneRIF Biological Term Annotations	1.0	null
UGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98975
CD248	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90024
Rectum adenocarcinoma_READ_TCGA-F5-6702-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
0179445-0000-3736	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MC-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCIMY7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6294
fallopian tube	GTEx Tissue Gene Expression Profiles	-1.0	-0.887209
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43758
Sarcoma_SARC_TCGA-DX-A6B8-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thalidomide-2258	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2030	CCLE Cell Line Gene CNV Profiles	1.0	2.0071
SNU324	CCLE Cell Line Gene CNV Profiles	1.0	1.55999
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
JHOS2	CCLE Cell Line Gene CNV Profiles	1.0	1.65946
TCCSUP	GDSC Cell Line Gene Expression Profiles	1.0	2.47116
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
RPMI7951	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44879
SNB19	BioGPS Cell Line Gene Expression Profiles	1.0	0.89838
BT20	CCLE Cell Line Gene CNV Profiles	1.0	1.93509
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.72433
integument	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
harmalol-5076	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CDC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71863
OVCAR3	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
Lung adenocarcinoma_LUAD_TCGA-75-5147-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RB-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-157	GDSC Cell Line Gene Expression Profiles	1.0	1.43162
chlorpropamide-5391	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC5550886-cddis2017345x3.xlsx-siRAD21_DEGs_NOT_rescued_by_Myc-Unnamed_1_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4317	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47877
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.917469
including	GeneRIF Biological Term Annotations	1.0	null
reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.225229
Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.316
SKES1	CCLE Cell Line Gene CNV Profiles	1.0	1.73688
SLC39A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34239
alfuzosin-4644	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Sarcoma_SARC_TCGA-QQ-A5VC-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEPG2	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.20249
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FU-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8404-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DL-PPMP-1121	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55739
Brain Lower Grade Glioma_LGG_TCGA-S9-A7QX-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sicilian	GeneRIF Biological Term Annotations	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22427
ctp11	GeneRIF Biological Term Annotations	1.0	null
CDC42EP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28326
MG-132-1140	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TP63	JASPAR Predicted Transcription Factor Targets	1.0	null
bromopride-2182	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
melanoma cell line	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
foliosidine-3739	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
skin	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
D-423MG	GDSC Cell Line Gene Expression Profiles	1.0	1.66665
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64245
SHF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69478
PADI4	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Z-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL-29	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
XBP1_OE_GDS2861_60_human_MCF7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
thapsigargin-7100	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.12
NRN1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66505
CCK-81	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.53061
Rectum adenocarcinoma_READ_TCGA-EI-6513-01A-21R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAGE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45006
Secondary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
SAOS2	BioGPS Cell Line Gene Expression Profiles	1.0	1.67882
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12655
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
KALS-1	GDSC Cell Line Gene Expression Profiles	1.0	1.99985
H4	GDSC Cell Line Gene Expression Profiles	1.0	1.62
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A680-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
undescended	GeneRIF Biological Term Annotations	1.0	null
C21orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30445
GSU	CCLE Cell Line Gene CNV Profiles	1.0	1.59598
BT474	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51974
M14	GDSC Cell Line Gene Expression Profiles	-1.0	-1.95424
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
IPO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72023
DSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17428
NCIH28	CCLE Cell Line Gene CNV Profiles	1.0	1.49044
Brain Lower Grade Glioma_LGG_TCGA-HT-8114-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTPN21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05964
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10U-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.877972
significant	GeneRIF Biological Term Annotations	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70O-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUDHL10	CCLE Cell Line Gene CNV Profiles	1.0	2.36415
Lung squamous cell carcinoma_LUSC_TCGA-85-7843-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
esophagus	HPA Tissue Protein Expression Profiles	1.0	1.61187
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RV-02A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TPGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62852
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.706901
DBTRG-05MG	GDSC Cell Line Gene Expression Profiles	1.0	1.93256
Kidney Chromophobe_KICH_TCGA-KO-8403-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD19+_BCells(neg._sel.)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.960186
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
spanxb	GeneRIF Biological Term Annotations	1.0	null
HCT15	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.73711
COV362	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
cisplatin_homo sapiens_gpl570_gds3910	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
U20S	BioGPS Cell Line Gene Expression Profiles	1.0	1.20792
LOX IMVI	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
nucleus	GO Cellular Component Annotations 2015	1.0	null
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03483
Lung adenocarcinoma_LUAD_TCGA-75-7027-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.07011
Brain Lower Grade Glioma_LGG_TCGA-DB-A75M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
melanoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.495
PRC_DEPLETION_GDS3532_96_human_U2OS cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03802
RAB6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3418
cancertestis	GeneRIF Biological Term Annotations	1.0	null
HMGB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80898
intracellular part	GO Cellular Component Annotations 2015	1.0	null
EB1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74128
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
Familial combined hyperlipidaemia_lymphoblast_GSE1010	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.49308
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A2I2-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4699-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13I-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GYG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83873
Oligospermia	HuGE Navigator Gene-Phenotype Associations	1.0	null
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.5112
c-MYC_KD_GDS2526_110_human_BT-474 BREAST CANCER cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anisomycin-5364	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79795
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43041
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91661
spermatozoa	GeneRIF Biological Term Annotations	1.0	null
CASP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86666
male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.344207
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-1.12486
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825378
Uveal melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
syndrome	GeneRIF Biological Term Annotations	1.0	null
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
PTEN_KD_GDS2958_99_human_A431 - EPIDERMOID carcinoma cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61885
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.892493
dosage	GeneRIF Biological Term Annotations	1.0	null
PMC9805873-Supp_Data.xlsx-dCas9-SALL1-SDS3_SEL1L_pool-id_SALL1	Rummagene Transcription Factor Associations 2026	1.0	null
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6399-01A-12R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLK1_knockdown_98_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.95774
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7397-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
comparing	GeneRIF Biological Term Annotations	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.935201
TestisIntersitial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.921402
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5086
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL33	CCLE Cell Line Gene CNV Profiles	1.0	1.34633
NCI-H2126	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.051
Epithelioid cell melanoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
cervix uteri	GTEx Tissue Gene Expression Profiles	-1.0	-0.887209
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.00085
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11993
JUND	JASPAR Predicted Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-KF-A41W-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW1271	CCLE Cell Line Gene CNV Profiles	1.0	1.61448
testes	GeneRIF Biological Term Annotations	1.0	null
class	GeneRIF Biological Term Annotations	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03483
NCIH2172	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15936
PMC9376070-41419_2022_5157_MOESM15_ESM.xlsx-Sheet1-Table_S1_Differentially_expressed_genes_of_CYTOR-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
ABC1	CCLE Cell Line Gene CNV Profiles	1.0	1.3886
YBX1_01_255	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.11766
SUPT20H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74017
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.11327
HCC1599	CCLE Cell Line Gene CNV Profiles	1.0	2.20545
ejaculated	GeneRIF Biological Term Annotations	1.0	null
c-MYC_KD_GDS2526_109_human_Hela cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.61187
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
KRAS.600.LUNG.BREAST_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Acute Myeloid Leukemia_LAML_TCGA-AB-2959-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.43329
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
ISOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94197
6-benzylaminopurine-3726	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85055
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7429-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1571
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962567
HOXA10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70854
liver	GTEx Tissue Gene Expression Profiles	-1.0	-0.887209
c-MYC_KD_GDS2526_112_human_MCF-7 BREAST CANCER cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GM2313	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.897732
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040512
Brain Lower Grade Glioma_LGG_TCGA-QH-A870-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHA-00846566E-7086	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.50926
Lung squamous cell carcinoma_LUSC_TCGA-33-6738-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABCB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6962
CDKN2AIPNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51918
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91033
LB831-BLC	GDSC Cell Line Gene Expression Profiles	1.0	1.42918
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A6RY-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30875
BICR10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
pentetic acid-4669	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST18-Supplementary_Data_18_Gene_burden_for_deletions_by_subtype_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
organelle	GO Cellular Component Annotations 2015	1.0	null
XIAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23656
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
MTRES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07783
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837618
LCLC-103H	GDSC Cell Line Gene Expression Profiles	1.0	2.15716
GABPA	ENCODE Transcription Factor Targets	1.0	null
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44719
SHROOM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36348
TAGLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78441
Lung adenocarcinoma_LUAD_TCGA-55-6975-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UNC119B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85074
Prestwick-675-3682	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.934511
1321N1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71534
GAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44483
zimeldine-1930	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848358
NCIH841	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00352
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22362
12,13-EODE-1108	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
male	GeneRIF Biological Term Annotations	1.0	null
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837618
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.12127
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A539-01A-31R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
betonicine-3745	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13472
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.293278
OVCA 429	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.988983
prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.351187
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55635
hydralazine-3724	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tyrphostin AG-1478-1141	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
azoospermia; infertility, male; oligospermia	GAD Gene-Disease Associations	1.0	null
PMC2694838-1471-2164-10-241-S2.xls-Sheet1-Regulated_genes_by_ZNF191_knockdown_ZNF24	Rummagene Transcription Factor Associations 2026	1.0	null
carbenoxolone-3353	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6945-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44572
STYX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78211
tiaprofenic acid-4091	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-371-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15148
pirinixic acid-481	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6003-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
Melanoma	DisGeNET Gene-Disease Associations	1.0	null
17709385-Table1	GeneSigDB Published Gene Signatures	1.0	null
SDHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17371
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.893168
Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7158
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cutaneous	GeneRIF Biological Term Annotations	1.0	null
haloperidol-1628	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MRPL40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19884
YBX1_01_257	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.24599
CAL12T	CCLE Cell Line Gene CNV Profiles	1.0	1.87189
population	GeneRIF Biological Term Annotations	1.0	null
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.18925
SLC35E2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99882
Brain Lower Grade Glioma_LGG_TCGA-TM-A84L-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRKCA_knockdown_118_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.03404
Choroid cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
TGBC1TKB	GDSC Cell Line Gene Expression Profiles	1.0	1.56439
cisplatin_homo sapiens_gds3910	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SS-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T4-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
melanocyte	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_TAZ-CAMTA1_vs_EV-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
H3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98491
Papillary Carcinoma of the Thyroid_Thyroid Gland (MMHCC)_GSE3678	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.65609
JJN3	CCLE Cell Line Gene CNV Profiles	1.0	1.43198
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.385
antigens	GeneRIF Biological Term Annotations	1.0	null
HIPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56382
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14149
UROD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66679
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Rectum adenocarcinoma_READ_TCGA-F5-6810-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUDT19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20843
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4698-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0341
PMC3470785-NIHMS377161-supplement-3.pdf-421-HOXB1_HOXB1	Rummagene Transcription Factor Associations 2026	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.939735
19658189-TableS4	GeneSigDB Published Gene Signatures	1.0	null
NOTCH_INHIBITION_GDS2794_61_human_MOLT4 (T-cell acute lymphoblast leukemia) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
patient	GeneRIF Biological Term Annotations	1.0	null
ERCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96601
CD8+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.91255
decitabine_homo sapiens_gpl571_gse29077	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCEA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28581
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6356-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5302-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BW-B70C-1132	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040706
Pancreatic adenocarcinoma_PAAD_TCGA-F2-A44G-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spermatids	GeneRIF Biological Term Annotations	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.7116
A172	CCLE Cell Line Gene CNV Profiles	-1.0	-2.12726
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.1397
HCC1937	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38124
velnacrine-4997	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7588-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
downs	GeneRIF Biological Term Annotations	1.0	null
BHT101	CCLE Cell Line Gene CNV Profiles	1.0	1.66406
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.64371
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
fenoprofen-3612	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TestisLeydigCell	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31116
ARHGDIB_Transfection_GDS4455_551_human_UM-UC-3 bladder carcinoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.415
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5683-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03802
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.818172
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67759
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caffeic acid-5352	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
IFT140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60121
reproduction	GAD High Level Gene-Disease Associations	1.0	0.293278
TOB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11769
breast	GTEx Tissue Gene Expression Profiles	1.0	0.874773
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.787
Prestwick-691-4092	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
raubasine-5459	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SKMEL3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7611
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4772
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03483
loxapine-6694	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAPK1_knockdown_112_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.80818
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85055
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H1 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.10419
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15148
naftifine-3536	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.08163
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.69901
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J8-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6855629-pone.0225186.s009.xlsx-Sheet1-DEGs_downregulated_in_HEK293_MEIS1_KO_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
COA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86185
Ocular cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.259
CAVIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84269
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.960386
GPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62208
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YR-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10709142-41556_2023_1281_MOESM2_ESM.xlsx-Supplementary_Table_1-CLUSTER_2_MAF_downregulated_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
salivary gland	GTEx Tissue Gene Expression Profiles	-1.0	-0.887209
NCIH1651	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36787
B4GALT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8542
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.21016
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cytochalasin B-1122	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.934511
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91326
VLDLR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29826
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55863
Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
HNF1B	JASPAR Predicted Transcription Factor Targets	1.0	null
HOP92	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.942212
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.864465
COLO-205	GDSC Cell Line Gene Expression Profiles	-1.0	-1.93938
Brain Lower Grade Glioma_LGG_TCGA-HT-A5R9-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prestwick-559-1728	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ROCK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39457
hydrastinine-5075	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A3-KAW	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.53061
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.878927
UBB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58903
Prestwick-674-3716	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.104
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WO-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45R-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.338909
NUGC4	CCLE Cell Line Gene CNV Profiles	1.0	1.52754
PIAS1_Depletion_GDS5076_12_human_MDA-MB 231 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342