association	dataset	threshold value	standardized value
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:O24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03758
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4713-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46B-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UPCISCC116	DepMap CRISPR Gene Dependency	1.0	4.32153
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24012
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.863
CRCGN008_HEPG2_24H:M12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01535
LU99	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54364
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845041
Primary sclerosing cholangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
hsa-miR-4747-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CRCGN010_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11103
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-1596-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76741
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1438
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7379-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5088-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WN-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92945
496100447_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15447
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.434
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.57965
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1353
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3408
SNB75	CCLE Cell Line Gene CNV Profiles	1.0	1.64289
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.51438
143B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.899123
496100419_TCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.23172
CRCGN016_MCF10A.TP53.M_24H:M09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32362
ECC12	CCLE Cell Line Gene CNV Profiles	1.0	1.52614
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9365
CRCGN012_HEPG2_24H:G18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.06902
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FP-01A-21R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01889
JHH1	CCLE Cell Line Gene CNV Profiles	1.0	1.74207
T3M4	CCLE Cell Line Gene CNV Profiles	1.0	1.7274
CRCGN014_HEPG2_3H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7438
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.909
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861861
NUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	1.49636
hsa-miR-548aa	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55668
CRCGN016_MCF10A.TP53.M_24H:F14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.87546
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4799-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.69046
CRCGN014_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8495
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7183-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68043
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44401
CRCGN008_HEPG2_24H:G24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9837
SNU1076	CCLE Cell Line Gene CNV Profiles	1.0	2.85171
Lung adenocarcinoma_LUAD_TCGA-55-7570-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUGC2	CCLE Cell Line Gene CNV Profiles	1.0	2.33839
MEWO	CCLE Cell Line Gene CNV Profiles	-1.0	-2.83158
Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9067
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6936
HMC18	CCLE Cell Line Gene CNV Profiles	1.0	1.97989
membrane part	GO Cellular Component Annotations 2015	1.0	null
CRCGN015_MCF10A_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28734
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83691
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	154.945
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.1468
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53205
CRCGN016_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32059
Rectum adenocarcinoma_READ_TCGA-F5-6810-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7877
Kidney Chromophobe_KICH_TCGA-KN-8435-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_3H:A05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22223
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.725
496100443_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.92637
ISTMES1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37975
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.33752
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.614
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GZ-05A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2143
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4269
developmental process	GO Biological Process Annotations 2015	1.0	null
496100619_HIP_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.88819
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873599
Progressive familial heart block	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.482
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7067-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE270	DepMap CRISPR Gene Dependency	1.0	3.562
Prostate adenocarcinoma_PRAD_TCGA-HC-8259-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TE1	DepMap CRISPR Gene Dependency	1.0	3.29294
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29561
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28377
Prostate adenocarcinoma_PRAD_TCGA-V1-A8MK-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1134
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.66701
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3WX-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	135.777
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8963
Kidney Chromophobe_KICH_TCGA-KL-8324-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UPCISCC040	DepMap CRISPR Gene Dependency	1.0	3.98531
Cholestasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
CRCGN014_HEPG2_24H:P01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.17924
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.53614
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06123
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.04696
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
SIHA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909141
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2105
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34183
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.2375
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5341
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	94.0925
Sarcoma_SARC_TCGA-QQ-A5VC-01A-31R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91333
biological_process	GO Biological Process Annotations 2015	1.0	null
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2711
BEN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69673
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100420_PCx_probable Alzheimer's disease_no TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.93918
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5341
CRCGN013_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42687
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5433
Adrenocortical carcinoma_ACC_TCGA-PA-A5YG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4338-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549	DepMap CRISPR Gene Dependency	1.0	2.35761
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.84301
Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WL-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.68055
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.08777
HT3	DepMap CRISPR Gene Dependency	1.0	4.46101
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.91027
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
C2BBE1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.50256
Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EGR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.4918
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NJ-01A-22R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-544	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04772
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87467
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5024
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	269.138
Hypospadias	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.418
CRCGN014_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9598
hsa-miR-376c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100572_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09272
LS180	DepMap CRISPR Gene Dependency	1.0	4.89192
NCIH23	DepMap CRISPR Gene Dependency	1.0	2.90293
hsa-miR-548z	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66659
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87467
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYO1	DepMap CRISPR Gene Dependency	1.0	2.98679
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0617
ZNF253	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75306
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5309
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04483
Phimosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.212
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5369
CRCGN015_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43058
CRCGN016_MCF10A.TP53.M_24H:D18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6403
EGR1	JASPAR Predicted Transcription Factor Targets	1.0	null
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15878
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-3191	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
CRCGN010_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35241
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50547
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.75685
VMRCLCP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42315
21NT	DepMap CRISPR Gene Dependency	1.0	3.59863
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.1861
Kidney Chromophobe_KICH_TCGA-KN-8430-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5255
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5B-Up_H3K4me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6207
Prostate adenocarcinoma_PRAD_TCGA-G9-6367-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	158.937
CRCGN015_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39408
CRCGN012_HEPG2_24H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00788
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	100.09
hsa-miR-4684-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.60087
SNU449	CCLE Cell Line Gene CNV Profiles	1.0	2.13944
JM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77465
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WV-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney renal papillary cell carcinoma_KIRP_TCGA-IA-A83V-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Male urethra	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.092
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70N-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE264621_1_v_3_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3816
H3255	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.83684
COLO680N	CCLE Cell Line Gene CNV Profiles	1.0	1.33014
THP1	CCLE Cell Line Gene CNV Profiles	1.0	1.33845
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27615
C32	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35323
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.878
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07002
Mucolipidosis type IV	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z3-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A703-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5024
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56821
Head and Neck squamous cell carcinoma_HNSC_TCGA-HL-7533-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A49I-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	168.307
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978874
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.65945
Outer dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.541
CRCGN011_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4822
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01095
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5930-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.0836
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5586
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41526
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20676
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
SATB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.18
496100671_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1992
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.62618
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-A5HZ-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.42387
Pulmonary large cell neuroendocrine carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.025
CRCGN013_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48035
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7363
gamete generation	GO Biological Process Annotations 2015	1.0	null
CRCGN015_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12571
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873599
HCC38	DepMap CRISPR Gene Dependency	1.0	2.86797
NCIH1048	DepMap CRISPR Gene Dependency	1.0	3.47002
single-organism process	GO Biological Process Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2687-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
95T1000	DepMap CRISPR Gene Dependency	1.0	2.12462
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4652-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B1-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6936-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CA-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bile duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.346
496100632_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09201
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	145.847
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.21565
SNU638	DepMap CRISPR Gene Dependency	1.0	4.8785
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9491
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66139
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34378
CRCGN016_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33855
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.263
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4217
CRCGN017_MCF10A.WT.HP_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.29854
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JF-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0799
Kidney Chromophobe_KICH_TCGA-KN-8433-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66659
MDAMB468	DepMap CRISPR Gene Dependency	1.0	3.7102
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9906
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4707-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HGC27	CCLE Cell Line Gene CNV Profiles	1.0	1.34218
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.01195
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4347
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE150134_1_v_0_scn5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01207
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A642-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU668	DepMap CRISPR Gene Dependency	1.0	3.25469
NUGC4	CCLE Cell Line Gene CNV Profiles	1.0	2.62035
Lung adenocarcinoma_LUAD_TCGA-44-5644-01A-21R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KATOIII	DepMap CRISPR Gene Dependency	1.0	2.33201
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HD-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gonocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.718
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14347
CRCGN012_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.47482
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.929462
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2616
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.8743
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4881-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.930573
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0541
KYSE150	DepMap CRISPR Gene Dependency	1.0	3.67493
T3M4	DepMap CRISPR Gene Dependency	1.0	2.08017
TKKK	DepMap CRISPR Gene Dependency	1.0	2.08439
Prostate adenocarcinoma_PRAD_TCGA-G9-6370-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548ac	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
HCC461	DepMap CRISPR Gene Dependency	1.0	5.0702
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8639
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80677
HT-29	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34183
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.94194
OSC-19	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.83684
NCIH441	DepMap CRISPR Gene Dependency	1.0	3.99626
cellular_component	GO Cellular Component Annotations 2015	1.0	null
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4117
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845041
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100604_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.73096
CTCF	ENCODE Transcription Factor Targets	1.0	null
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1299
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EJ-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100612_HIP_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.79718
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861861
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SKMEL31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63107
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29999
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN016_MCF10A.TP53.M_24H:D15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09607
HCA1	DepMap CRISPR Gene Dependency	1.0	3.74786
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7232
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
CRCGN014_HEPG2_24H:B06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13114
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.08075
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
SNU1	DepMap CRISPR Gene Dependency	1.0	3.97464
Ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.798
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RT-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30468
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-02A-12R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100548_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.49497
AMO1	DepMap CRISPR Gene Dependency	1.0	3.68065
59M	DepMap CRISPR Gene Dependency	1.0	5.3746
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOZ	DepMap CRISPR Gene Dependency	1.0	3.1243
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87467
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.7266
Autoimmune hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.219
EFM19	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93951
EGR4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	87.0323
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20787
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.32401
CRCGN016_MCF10A.TP53.M_24H:P18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95844
ARMCX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06714
CRCGN015_MCF10A.WT.HP_24H:B04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07233
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Domain of unknown function DUF4599	InterPro Predicted Protein Domain Annotations	1.0	null
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73339
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41621
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7287-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4012
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.87835
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861861
HCC70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21143
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-574-ZSCAN1_ZSCAN1	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN011_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34845
Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T3-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.116
Biliary epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.932
Polycystin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.764
single organism reproductive process	GO Biological Process Annotations 2015	1.0	null
Cholangiocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.368
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.53801
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0972
Sarcoma_SARC_TCGA-LI-A67I-01A-31R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	275.887
CRCGN014_HEPG2_24H:A03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65157
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.973197
hsa-miR-3190	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NK-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.58355
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2931
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1371
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.28697
CRCGN014_HEPG2_24H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20625
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77542
HEC108	CCLE Cell Line Gene CNV Profiles	1.0	1.79521
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.9704
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2ND-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1581	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52254
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	193.473
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2499
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.75317
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4790-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7777
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873599
spermatogenesis	GO Biological Process Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F1-01A-11R-A034-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71235
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21239
Primary biliary cholangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.594
Sperm plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.882
CAL27	DepMap CRISPR Gene Dependency	1.0	2.07573
CRCGN013_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11036
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9776
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Deprivation amblyopia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.671
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93685
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.629
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9713
Rectum adenocarcinoma_READ_TCGA-DC-6154-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SKMEL30	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55428
CRCGN014_HEPG2_24H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0885
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Megalocornea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.459
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Liver cirrhosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-196-ZNF658_ZNF658	Rummagene Transcription Factor Associations 2026	1.0	null
KNS42	CCLE Cell Line Gene CNV Profiles	1.0	1.8474
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01207
Lung adenocarcinoma_LUAD_TCGA-91-A4BC-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9868
NCIH2087	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32472
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978874
hsa-miR-186	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.99815
chr9_66972902_G_A_b38	GTEx eQTL 2025	1.0	1.41998
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.39403
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
KLF11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.6889
Kidney Chromophobe_KICH_TCGA-KM-8639-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMBC2	CCLE Cell Line Gene CNV Profiles	1.0	1.91197
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.04803
CRCGN016_MCF10A.TP53.M_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4775
SCML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61818
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A54R-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9727756-media-2.pdf-82-RAX2_RAX2	Rummagene Transcription Factor Associations 2026	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PMC3804941-supp_jem.20122709_JEM_20122709_TableS1.xlsx-Suppl_Table_1C-1772_genes-Table_S1_C_1_772_significantly_overexpressed_genes_during_AR_when_combining_p-values_at_FDR_20_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8422-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3419
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83691
NCIH196	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39066
Inner dynein arm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.601
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7178
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4455
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87467
Mutilating palmoplantar keratoderma with periorificial keratotic plaques	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.61067
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87467
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	124.148
ZNF664	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47219
CRCGN016_MCF10A.TP53.M_24H:E14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25509
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.9292
NOMO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47055
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.06731
Brain Lower Grade Glioma_LGG_TCGA-DH-A7UU-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4341-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5000-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PI-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7793-01A-31R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JL-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary Biliary Cirrhosis	DisGeNET Gene-Disease Associations	1.0	null
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00345
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.53
Lung adenocarcinoma_LUAD_TCGA-55-A493-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100547_HIP_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.90404
CRCGN016_MCF10A.WT.HP_24H:P22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7995
Acute Myeloid Leukemia_LAML_TCGA-AB-2845-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873599
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909141
SUPM2	DepMap CRISPR Gene Dependency	1.0	5.03375
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01095
ZR751	DepMap CRISPR Gene Dependency	1.0	2.3926
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.44356
Prostate adenocarcinoma_PRAD_TCGA-HC-7742-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96714
CRCGN017_MCF10A.WT.HP_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1662
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861861
Lung adenocarcinoma_LUAD_TCGA-50-5072-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74135
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RP-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.16925
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14592
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.19105
hsa-miR-548d-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
CH157MN	DepMap CRISPR Gene Dependency	1.0	2.553
Biliary tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
EFO-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.73666
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.14723
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.2663
Prostate adenocarcinoma_PRAD_TCGA-G9-6384-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vesicle tethering complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.506
SNU349	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48171
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7263-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3909
GSE135400_2_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.29241
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
CRCGN013_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33014
Large cell neuroendocrine carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.445
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58666
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27615
CRCGN010_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4065
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Pulmonary neuroendocrine tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.10404
PMC11979751-table_s2_markers_elad055.xlsx-Melanoma_state_immune_markers-AP1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08219
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.19395
cell differentiation	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZT-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKRC31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92465
CACO2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66369
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-645-ENSG00000274349_ZNF658	Rummagene Transcription Factor Associations 2026	1.0	null
KMS12BM	CCLE Cell Line Gene CNV Profiles	1.0	1.76834
Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFKB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8311
CRCGN011_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.9541
JHOS4	DepMap CRISPR Gene Dependency	1.0	2.19253
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.54477
hsa-miR-4752	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
496100472_PCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.76099
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GARP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.003
CRCGN011_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.4069
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	147.523
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A3MI-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.74987
CRCGN014_HEPG2_24H:E01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23854
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JO-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS888T	CCLE Cell Line Gene CNV Profiles	1.0	2.05791
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7918-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12395
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5163-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU423	CCLE Cell Line Gene CNV Profiles	1.0	1.56494
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87467
male gamete generation	GO Biological Process Annotations 2015	1.0	null
hsa-miR-4712-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CRCGN016_MCF10A.TP53.M_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9359
Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chronic closed-angle glaucoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.57
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.09673
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15878
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autoimmune disease of gastrointestinal tract	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
JMURTK2	DepMap CRISPR Gene Dependency	1.0	4.17263
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.86647
1321N1	CCLE Cell Line Gene CNV Profiles	1.0	1.33878
SLR24	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94497
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QG-01A-12R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.924
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82345
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.05086
PK1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47864
HUT78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9228
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Ciliary muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.973
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.74003
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845041
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	199.238
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.83615
GSE169205_3_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2141	CCLE Cell Line Gene CNV Profiles	1.0	1.36376
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5063
Adrenocortical carcinoma_ACC_TCGA-OR-A5K5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08219
multicellular organismal reproductive process	GO Biological Process Annotations 2015	1.0	null
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6886
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51335
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.50745
SUPT1	DepMap CRISPR Gene Dependency	1.0	2.82758
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.5
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.8939
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11662
Pleomorphic carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.1
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15753
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.9025
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873599
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.056
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.61673
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
SUPHD1	CCLE Cell Line Gene CNV Profiles	1.0	1.58238
SNU719	DepMap CRISPR Gene Dependency	1.0	3.12121
Anterior segment dysgenesis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.062
496100396_HIP_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21402
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1815
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1564
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7846
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Familial episodic pain syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.45615
Peritubular contractile cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15878
DU 145	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.0953
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15753
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976462
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845041
CRCGN009_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.78273
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89664
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.8216
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A7U8-06A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Axonemal dynein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.381
VCY1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40782
HEC265	DepMap CRISPR Gene Dependency	1.0	3.76596
cellular process	GO Biological Process Annotations 2015	1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6145
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.188
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3341
PMC10679662-mmc2.xlsx-NC-D3-ZEB2-siRNA-Downregulated-Unnamed_7_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87467
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A702-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3912
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A704	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32885
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3254
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.55262
CRCGN009_HEPG2_24H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7811
NCIH3255	CCLE Cell Line Gene CNV Profiles	-1.0	-2.40816
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3848
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19703
CRCGN011_HEPG2_24H:C08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23145
CRCGN011_HEPG2_24H:J13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5096
CRCGN015_MCF10A_48H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13045
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.692
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7435-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3466-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.63048
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.929462
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4860-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6941-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24728
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.8462
F5	DepMap CRISPR Gene Dependency	1.0	3.25425
CRCGN009_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.59452
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.845041
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978874
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45656
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.1715
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.99902
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34183
Sclerosing cholangitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
Lung adenocarcinoma_LUAD_TCGA-75-5147-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56965
Biliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.305
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	131.768
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08219
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.978874
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.089
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0895
Bile duct disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
Barrett's esophagus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27615
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CRCGN011_HEPG2_24H:M15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20815
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50185
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05496
496100421_PCx_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.81254
MEL285	DepMap CRISPR Gene Dependency	1.0	2.94927
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5182-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.06133
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01095
Bladder Urothelial Carcinoma_BLCA_TCGA-YC-A8S6-01A-31R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.322
CRCGN012_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00063
MKN74	CCLE Cell Line Gene CNV Profiles	1.0	1.46866
Lung adenocarcinoma_LUAD_TCGA-44-7670-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.6314
CRCGN015_MCF10A.TP53.M_24H:B17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04065
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4169
reproductive process	GO Biological Process Annotations 2015	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:G19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3251
CRCGN014_HEPG2_3H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32659
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5319
496100654_HIP_no dementia_no TBI_86_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.6418
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.77512
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9091
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.93586
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Prostate adenocarcinoma_PRAD_TCGA-V1-A8WN-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EFO27	DepMap CRISPR Gene Dependency	1.0	2.03594
496100321_HIP_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14748
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3294
HSC1	DepMap CRISPR Gene Dependency	1.0	3.45049
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8003-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CFPAC1	DepMap CRISPR Gene Dependency	1.0	5.15089
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7635
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5001-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8260-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	127.529
CRCGN016_MCF10A.TP53.M_24H:O09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00688
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.939817
ICC10	DepMap CRISPR Gene Dependency	1.0	2.12574
KIJK	CCLE Cell Line Gene CNV Profiles	1.0	1.40107
Sarcoma_SARC_TCGA-QQ-A8VG-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH716	CCLE Cell Line Gene CNV Profiles	-1.0	-1.85948
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04772
hsa-miR-2110	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE264621_1_v_6_secretin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cryoglobulinemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.469
NUGC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.33645
HCC1419	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65666
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.1592
KMRC1	DepMap CRISPR Gene Dependency	1.0	3.33958
WM983B	CCLE Cell Line Gene CNV Profiles	1.0	1.40981
Bile duct epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.334
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	148.182
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1052
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3923-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.28527
RBE	DepMap CRISPR Gene Dependency	1.0	2.46204
CRCGN016_MCF10A.TP53.M_24H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.61125
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.873599
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54716
cellular developmental process	GO Biological Process Annotations 2015	1.0	null