association	dataset	threshold value	standardized value
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.882631
CRCGN017_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16557
CRCGN014_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.48608
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.997044
precentral gyrus, right, superior lateral aspect of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.968231
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5651
496100406_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.55101
MOSMO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.86251
Prostate adenocarcinoma_PRAD_TCGA-G9-7525-01A-31R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08583
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.50911
496100604_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.03811
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07556
Perturb_12644_KD_SIRT5_SRP311327	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36149
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.849357
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12438
GUSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42976
FBXO46	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40767
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.16918
CRCGN013_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46735
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24753
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18293
Perturb_2124_KD_NFKBIA_SRP285793	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.10993
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.05692
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6628
Kidney Chromophobe_KICH_TCGA-KN-8423-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.930831
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-134	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.7718
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.997044
POLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48277
biological_process	GO Biological Process Annotations 2015	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8041-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UCKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16391
VMA21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84069
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5142
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.8954
BEST2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97602
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IX-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_9855_KD_MSI2_SRP096137	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.18655
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.8596
Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T3-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4790-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9173
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TB-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M6-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5509-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.81725
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0611
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.854567
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85424
NCIH1648	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5878
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28141
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7891-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.3656
Perturb_13700_KD_HEPACAM2_SRP257754	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.02429
HDAC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77886
ZNF205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08363
Kidney Chromophobe_KICH_TCGA-KN-8419-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EWS-ERG-20517297-CADO-ES1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.143
supramarginal gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19747
Lung adenocarcinoma_LUAD_TCGA-MN-A4N4-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.95895
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M6-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MC116	CCLE Cell Line Gene CNV Profiles	1.0	1.70336
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
molecular layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13613
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.95895
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
middle frontal gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.84842
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03932
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24434
Prostate adenocarcinoma_PRAD_TCGA-G9-6364-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.94187
496100444_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.8901
inferior temporal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.958586
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4584
LPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36642
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESS1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.82716
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2857
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06561
Rectum adenocarcinoma_READ_TCGA-EI-6506-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09729
pallidohypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.39073
precuneus, right, inferior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.938501
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8381
reproductive process	GO Biological Process Annotations 2015	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831609
DUSP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51126
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04077
UQCRHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57763
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980448
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20215
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4372
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18055
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14823
GSK3A_KD_GDS4305_184_human_U937 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.39735
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.6686
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.14412
496100304_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.69335
Lung adenocarcinoma_LUAD_TCGA-55-A493-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65991
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5775
496100452_HIP_possible Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.34089
GSE113817_0_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inferior temporal gyrus, right, bank of mts	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.842154
Acute Myeloid Leukemia_LAML_TCGA-AB-2972-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2732
PL45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55152
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4617-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1461
LONP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45774
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5968
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3505
lateral orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67781
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.7931
PRKAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64492
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13673
CRCGN012_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36358
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5156
CRCGN009_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.66314
Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I6-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152441,GSE152442_1_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4002
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63724
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9071
GSK3A_KD_GDS4305_182_human_THP-1 acute myeloid leukemia cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997647
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUGC2	CCLE Cell Line Gene CNV Profiles	1.0	2.53745
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.6192
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZJ-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64463
H2BC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38932
CRCGN017_MCF10A.WT.HP_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0447
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.919261
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10456
NCIH661	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39831
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02059
STAT1	ChEA Transcription Factor Targets	1.0	null
CEP164	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.93729
PGBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3781
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7216
cingulate gyrus, parietal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.77114
raphe nuclei of medulla	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.959404
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40516
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64822
ZNF497	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92643
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27421
CRCGN009_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.07023
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57878
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.0781
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3951
CRCGN015_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85275
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5031-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7348
GSE84678,GSE93902_3_v_0_bcl11b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18835
Prostate adenocarcinoma_PRAD_TCGA-G9-6361-01A-21R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A4IJ-01A-31R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100529_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31015
EPB41L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91821
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.930343
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0208
EOLA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09615
CRCGN014_HEPG2_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25879
LEPROT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51776
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.921714
ZNF680	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46246
KARPAS299	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62084
Brain Lower Grade Glioma_LGG_TCGA-HT-7856-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0407
CRCGN016_MCF10A.TP53.M_24H:F11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25464
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
EPLC272H	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37464
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A700-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17767
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.930343
occipital pole, left, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44615
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05211
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3749
LIMD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63797
PTPRU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63001
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z3-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	86.3506
fusiform gyrus, right, bank of cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.897873
FOXA1	JASPAR Predicted Transcription Factor Targets	1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9454
TCF7L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58384
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45448
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-A479-01A-31R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.581
posterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.954094
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.87955
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10243
SKNSH	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32647
HNRNPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33537
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.895761
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5783-01A-41R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
EFO-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58092
Perturb_2054_KD_CHERP_SRP354316	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.80601
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20273
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.931061
A549	CCLE Cell Line Gene CNV Profiles	1.0	2.1677
PA2G4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11414
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6329
PMC11392820-41556_2024_1475_MOESM3_ESM.xlsx-Supplementary_Table_9-Supplementary_Table_9_Expression_level_of_OTX2_targeted_genes_n_999_related_to_Figure_6_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.32289
dorsal lateral geniculate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27408
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.925513
Prostate adenocarcinoma_PRAD_TCGA-G9-7523-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33874
hsa-miR-548z	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5835
gamete generation	GO Biological Process Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO849	CCLE Cell Line Gene CNV Profiles	1.0	1.34771
UBE2H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58068
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60258
CRCGN014_HEPG2_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0769
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.859185
496100487_HIP_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5045
L33	CCLE Cell Line Gene CNV Profiles	1.0	1.88658
IZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.931131
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49A-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4865-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4697-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.3455
Adrenocortical carcinoma_ACC_TCGA-OR-A5JC-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548ac	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2643
CRCGN015_MCF10A_48H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1545
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.84897
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14804
ZNF619	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05471
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984684
multicellular organismal reproductive process	GO Biological Process Annotations 2015	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4747-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2980-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1083-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
GSE148657_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4465
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JK-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133516_0_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.931842
hsa-miR-4520a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
HOP62	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32389
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_338_OE_PBX1_SRP389513	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
PPP1R16A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64018
hsa-miR-376c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
ACCMESO1	CCLE Cell Line Gene CNV Profiles	1.0	1.36434
spermatogenesis	GO Biological Process Annotations 2015	1.0	null
JHH5	CCLE Cell Line Gene CNV Profiles	1.0	2.43513
SREBF2	JASPAR Predicted Transcription Factor Targets	1.0	null
GTF2E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58853
CI1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97182
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9457
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.0169
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86842
hsa-miR-3136-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
CRCGN012_HEPG2_24H:J20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06892
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DU145	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72557
IPC298	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50038
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IM95	CCLE Cell Line Gene CNV Profiles	1.0	1.50713
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14388
SERPINB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98646
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.931386
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.48568
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.862696
pontine raphe nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54779
Prostate adenocarcinoma_PRAD_TCGA-CH-5745-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
JDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18501
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.903409
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.50539
TE125T	CCLE Cell Line Gene CNV Profiles	1.0	1.56225
CRCGN017_MCF10A.TP53.M_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33753
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70037
central gray of the pons, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41752
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25711
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5539
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81E-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:B17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14955
TRAFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57853
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
middle temporal gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.996456
cingulate gyrus, retrosplenial part, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26992
SRSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06007
Domain of unknown function DUF4599	InterPro Predicted Protein Domain Annotations	1.0	null
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1065
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
SAR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.113
CRCGN017_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7074
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.832476
Prostate adenocarcinoma_PRAD_TCGA-EJ-7327-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6637
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
hsa-miR-4513	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Lung squamous cell carcinoma_LUSC_TCGA-18-3410-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79802
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43968
PNMA8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84107
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3093
DENND6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52152
Adrenocortical carcinoma_ACC_TCGA-OR-A5LA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.17494
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
GSE214583,GSE214585_1_v_0_steap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CCK81	CCLE Cell Line Gene CNV Profiles	1.0	1.65487
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9388
Pancreatic adenocarcinoma_PAAD_TCGA-Q3-A5QY-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.952758
NR3C1	ChEA Transcription Factor Targets	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09304
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0461
GSE185139_1_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100365_HIP_probable Alzheimer's disease_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.72913
CRCGN009_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01079
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4088
IZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.834325
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.5307
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.6667
Brain Lower Grade Glioma_LGG_TCGA-WY-A859-01A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_336_OE_PBX1_SRP389513	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.952414
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.863589
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50225
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79645
GSE178714_1_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MDA-MB-453	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78257
ENSG00000286190	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0636
REXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63354
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2059
AZI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3671
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.01822
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.82913
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
496100634_HIP_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.82897
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20273
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8024
IRF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30023
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superior temporal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29357
GCM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4243
inferior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.85478
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.895291
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5817
CRCGN010_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30605
TRAK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81448
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10025
SKMES1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84635
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.834976
DMS114	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44595
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.1051
PADI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40118
CRCGN014_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.202
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.00287
FOXF2	JASPAR Predicted Transcription Factor Targets	1.0	null
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.86738
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08601
ventral tegmental area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05058
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03587
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43062
TNPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71068
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6964
496100509_HIP_dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13242
ZNF879	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26692
EWSR1	ChEA Transcription Factor Targets	1.0	null
CRCGN009_HEPG2_24H:I17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11376
496100417_HIP_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2194
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
short insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.973193
NAPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67408
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.8366
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.70575
ACSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61999
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.47684
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.007
CRCGN016_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.53595
inferior frontal gyrus, orbital part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.46221
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.964463
Perturb_2121_KD_PRMT5_SRP276651	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.04092
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23892
RPP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13955
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	259.724
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11804
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8914
NOL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54545
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22872
MYOCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3963
cellular developmental process	GO Biological Process Annotations 2015	1.0	null
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82559
CRCGN012_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16716
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0461
OC316	CCLE Cell Line Gene CNV Profiles	1.0	1.42935
LK2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.58578
CRCGN015_MCF10A_48H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37579
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0461
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7925-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10165_KD_DOT1L_SRP292382	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.1452
brain	GTEx Tissue Gene Expression Profiles	1.0	1.46289
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EJ-01A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single organism reproductive process	GO Biological Process Annotations 2015	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NF-A4WU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00959
Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRMT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93588
IWS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87039
ARNT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66439
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.84311
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
HID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49674
HCT116	CCLE Cell Line Gene CNV Profiles	1.0	1.62106
Mesothelioma_MESO_TCGA-MQ-A4KX-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-3771-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.64521
CHSY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47385
Kidney Chromophobe_KICH_TCGA-KN-8426-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_10153_KO_ARID4B_SRP255645	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.86775
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16989
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.7402
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15056
Perturb_9945_KD_UTP18_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.91864
CRCGN015_MCF10A_48H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77341
GLIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62894
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6226
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72835
496100572_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.67193
CRCGN015_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82474
PMC11535030-44320_2024_65_MOESM1_ESM.pdf-44-ZNF780A_ZNF780A	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1238	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PPP1R26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30015
CRCGN017_MCF10A.WT.HP_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0646
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13899
hsa-miR-670	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91352
CRCGN015_MCF10A_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4511
hsa-miR-548d-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Sarcoma_SARC_TCGA-QQ-A8VH-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2221
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8783
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02204
SEMA3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75669
lateral nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.884208
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28438
ISHIKAWAHERAKLIO02ER	CCLE Cell Line Gene CNV Profiles	1.0	1.44878
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831609
Lung squamous cell carcinoma_LUSC_TCGA-60-2726-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JJN3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51425
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35678
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KM-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_PSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.36098
male gamete generation	GO Biological Process Annotations 2015	1.0	null
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1996
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853252
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831609
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8729
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86139
Prostate adenocarcinoma_PRAD_TCGA-FC-7708-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5089
OST4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42239
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.837285
CRCGN008_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93695
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24434
developmental process	GO Biological Process Annotations 2015	1.0	null
U2SURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97599
496100510_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21551
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5D1-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3244
KATOIII	CCLE Cell Line Gene CNV Profiles	1.0	1.81272
Heschl's gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.88702
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00408
TP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22411
NLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63227
adipose tissue	GTEx Tissue Gene Expression Profiles	-1.0	-0.869607
GSE211474,GSE212779_0_v_1_phf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZT-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53468
CRCGN012_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.54517
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.82115
cell differentiation	GO Biological Process Annotations 2015	1.0	null
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14699
Perturb_12645_KD_SIRT5_SRP311327	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5807
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.5161
CRCGN008_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1462
MEWO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66603
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SJ-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6388
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PI-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10826
SP in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11761
MZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.987418
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28438
CRCGN010_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66265
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852163
GSE224004,GSE224005_0_v_8_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18857
inferior frontal gyrus, triangular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.887262
GSE158674_1_v_2_fluoxetine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7256
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QX-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH650	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14047
OAW42	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54182
CRCGN015_MCF10A.WT.HP_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1351
PAX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17526
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0992
CFAP298	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50696
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6991
Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral posterior nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02292
TYKNU	CCLE Cell Line Gene CNV Profiles	-1.0	-1.71026
SJSA1	CCLE Cell Line Gene CNV Profiles	1.0	1.34382
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7476-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.66237
496100313_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.01539
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70565
CRTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42581
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12438
ID4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70678
ZNF432	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61925
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.59756
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.37347
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.18276
NOTCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99792
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02266
Prostate adenocarcinoma_PRAD_TCGA-EJ-5522-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.92487
GSE133329_2_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100321_HIP_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.1279
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.3526
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.1552
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.99915
dentate (lateral) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26149
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4688-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.73306
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1JX-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881881
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41941
hsa-miR-3118	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47088
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24434
posterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26571
CRCGN016_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.68817
TRIM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00067
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5885-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7177
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.07453
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.74159
HGC27	CCLE Cell Line Gene CNV Profiles	1.0	1.57505
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8743
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0671
CRCGN015_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32423
KP2	CCLE Cell Line Gene CNV Profiles	1.0	1.76959
Mesothelioma_MESO_TCGA-SC-A6LQ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2186
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53429
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4723-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
Perturb_2126_KO_SUMO1_SRP299611	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A678-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF665	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58943
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	148.673
thyroid	GTEx Tissue Gene Expression Profiles	-1.0	-1.06516
CPNE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50773
Sarcoma_SARC_TCGA-IS-A3K8-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.76123
AEBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5729
CRCGN017_MCF10A.WT.HP_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.98275
HPAC	CCLE Cell Line Gene CNV Profiles	1.0	1.89142
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1332
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.68534
PMC4773428-ncomms10751-s5.xlsx-S_Table_4-Supplementary_Data_4_RUNX1_responsive_genes_in_the_presence_and_absence_of_estradiol_E2_in_MCF7_cells_FC_1_5_p_0_05_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
IFIT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8973
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852163
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.88944
CRCGN010_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.92975
CRCGN012_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.625
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.04513
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7519
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26732
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-01A-21R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2435
ZNF155	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07716
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1455
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996849
SOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99377
Sarcoma_SARC_TCGA-HS-A5N8-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100629_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04207
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39055
CRCGN008_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8999
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.53371
Acute Myeloid Leukemia_LAML_TCGA-AB-2845-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22872
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.58895
hsa-miR-758	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
DFFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03951
MEG01	CCLE Cell Line Gene CNV Profiles	-1.0	-2.11172
AEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49807
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60386
pyramidal layer of caudal subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07633
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03288
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.035
pyramidal cells of rostral CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16918
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A545-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCAR4	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14396
E2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71752
H1-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71636
superior frontal gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10454
GSE193157_0_v_1_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USP32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69597
hsa-miR-1537	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54184
OVSAHO	CCLE Cell Line Gene CNV Profiles	1.0	1.38691
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.904574
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6022-01A-21R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.44525
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1633
Sarcoma_SARC_TCGA-MO-A47R-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus subputaminalis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841759
PSME3IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97219
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4863-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOLT3	CCLE Cell Line Gene CNV Profiles	1.0	1.32989
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08456
Perturb_87_KI_ETV4_SRP402451	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.07626
CRCGN011_HEPG2_24H:J13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3414
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05901
MSANTD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83297
RDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59999
IPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82304
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73F-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0475
hsa-miR-4520b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.52397
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q1-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44985
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IC-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FU97	CCLE Cell Line Gene CNV Profiles	1.0	1.53895
GTF2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2033
Kidney Chromophobe_KICH_TCGA-KL-8332-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.932
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.24818
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.8658
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-R2-A69V-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM174C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46042
496100312_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21779
PIGQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81825
SNB19	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68053
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2619
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5433
CRCGN017_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3762
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.20901
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.96
CRCGN016_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08889
Perturb_9956_KD_SFPQ_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.55504
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT1-20625510-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
planum temporale, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18091
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A69H-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM220A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90492
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41145
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN008_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4042
MSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18108
Lung squamous cell carcinoma_LUSC_TCGA-56-A49D-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0461
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6657
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853252
Sarcoma_SARC_TCGA-SG-A849-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.913407
496100520_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.31527
CRCGN011_HEPG2_24H:M15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11305
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.20621
OCIMY7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64872
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.3494
NR3C1-21868756-MCF10A-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.967077
KM12	CCLE Cell Line Gene CNV Profiles	1.0	2.08427
CRCGN008_HEPG2_24H:C15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0576
KLK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26576
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.54989
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.46436
Rectum adenocarcinoma_READ_TCGA-F5-6464-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:D03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00509
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23253
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:J07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09835
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78133
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49105
ARHGAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97628
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	1.0	7.21116
CRCGN011_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6994
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.40404
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.28295
PANC0813	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35753
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.54114
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.59066
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.81867
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.892997
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16873
CSDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95695
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.55097
LUC7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01096
L363	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40266
colon	GTEx Tissue Gene Expression Profiles	1.0	0.894089
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16384
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53411
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14814
496100477_HIP_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03238
CRCGN009_HEPG2_24H:H02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1902
Perturb_356_KD_ERK2_SRP308190	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.02751
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5888-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.09
olfactory tubercle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3861
SPI1	ENCODE Transcription Factor Targets	1.0	null
UMUC1	CCLE Cell Line Gene CNV Profiles	1.0	1.35552
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.955266
outer SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.996295
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ERAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14922
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06
hsa-miR-4712-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
single-organism process	GO Biological Process Annotations 2015	1.0	null
496100547_HIP_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43212
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05333
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14948
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28438
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.01271
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
JHH1	CCLE Cell Line Gene CNV Profiles	1.0	2.80109
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4770-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.047
CCDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49954
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47616
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2945
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.486
hsa-miR-4752	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
WM115	CCLE Cell Line Gene CNV Profiles	1.0	1.46842
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.59314
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.881881
Prostate adenocarcinoma_PRAD_TCGA-KK-A7B1-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMRCLCD	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81328
UMRC6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.661
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36296
CRCGN008_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9346
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4335
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7653
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40077
GSE206342_1_v_0_kpna2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DBTRG05MG	CCLE Cell Line Gene CNV Profiles	1.0	1.98651
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3567
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YI-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.02706
ZFP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72907
GSE128333_2_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.0073
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.997044
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9787
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.94597
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.20434
CRCGN015_MCF10A.WT.HP_24H:E22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0991
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0461
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4521
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.2769
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HF-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GUF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57822
KLHDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33418
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A3-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33746
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5071
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39237
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25876
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9837
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
HPS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7006
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.0544
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1947
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06561
CRCGN016_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.51303
PGGHG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36625
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.23603
perifornical nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.881674
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27421
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral hypothalamic area, anterior region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08512
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996849
LYAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0653
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1626
ACAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93467
Lung adenocarcinoma_LUAD_TCGA-55-A491-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GY-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN010_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0758
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4825
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.918478
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09304
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.931842
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32628
RIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1365
precentral gyrus, right, bank of the central sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21765
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0461
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.997233
MGMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00767
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1707
GSE133516_5_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2252
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100644_HIP_probable Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.04556
CRCGN015_HEPG2_48H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00131
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06561
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.57493
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01146
HS888T	CCLE Cell Line Gene CNV Profiles	1.0	1.69309
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1156
Rectum adenocarcinoma_READ_TCGA-AH-6547-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8422-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.832656
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2022
WM-266-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.47696
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5552-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985745
ZNF781	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87941
496100615_HIP_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.56583
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65B-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.940468
nucleus	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0522
Prostate adenocarcinoma_PRAD_TCGA-CH-5763-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-7489-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58553
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23892
Brain Lower Grade Glioma_LGG_TCGA-DU-7292-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997647
ELOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23514