association	dataset	threshold value	standardized value
TOMM70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20516
Oocyte meiosis	KEGG Pathways 2026	1.0	null
PYGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15984
SQLE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02354
RABEPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10553
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	95.9628
GPALPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28686
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4797
CHRNA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.13968
AMD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78096
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.186
GSE125403_7_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POM121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73769
CPTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60589
ATP6V0E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06159
NOP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5078
PCGF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87188
MAPRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4538
GPRASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05444
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8054
NCBP2AS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5464
DDX51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06556
PTER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30625
C3orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66221
ASH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02403
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0972
GPR143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07136
C9orf78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0238
ZFAND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37343
GFM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02189
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.71586
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2508
496100382_PCx_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03822
PPP1R8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23604
ZNF722	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16214
UFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58268
STK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33881
RHOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14024
TOMM20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82734
Brain - Nucleus accumbens (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.71586
ZNF860	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55332
chr7_74932314_T_A_b38	GTEx eQTL 2025	1.0	1.13057
SMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02283
KNOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61816
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2855
GSC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2033
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8949
METTL22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38664
THBD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0002
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9337
ZDHHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12389
NEDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19907
LIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59108
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1962
EIF4E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33384
FKBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37724
IMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2614
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2721
ANKRD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33475
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.1111
ELMOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50092
CIAO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05702
PPP2R3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25405
POLR3F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25646
NMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.54015
FNBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51817
GSE221327_8_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
FAM169A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18502
RNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05701
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.650507
protein kinase binding	GO Molecular Function Annotations 2025	1.0	null
STARD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06637
IRF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3819
RHOT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01144
KLF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02344
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6641
PMC12211054-spectrum.00100-25-s0002.pdf-69-SNAPC4_SNAPC4	Rummagene Transcription Factor Associations 2026	1.0	null
TSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0307
SDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8462
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.3893
FARSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34618
RTL8C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56756
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68747
CHST12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64944
GLRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35332
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7038
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.11984
FSTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35948
GPKOW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03336
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6121
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6495
NKX2-5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4423
TECPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14346
FBXL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68605
GSE234637_3_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF546	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05645
CENPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02626
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0525
TRIM62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37146
ZNF445	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19124
RBSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.219
MTREX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1884
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7944
MN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06564
PAX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3371
SPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02733
NUDT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56658
488395315_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.41828
UBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.596
MFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72398
kinase binding	GO Molecular Function Annotations 2025	1.0	null
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2795
TNFRSF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5336
USP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67132
DDX59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35442
PPIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63774
TSHZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3591
EIF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38959
GSE148200_0_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9467
PRPS1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39944
ELP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96832
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7497
CNTROB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35304
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7712
GTEx Brain 20-29 vs 30-39	GTEx Tissue-Specific Aging Signatures	1.0	4.20961
NSMAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33069
GSE130396_0_v_2_braf_human	RummaGEO Gene Perturbation Signatures	1.0	null
SYT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07674
AP1AR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00273
TMSB4Y	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88702
WBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01723
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.49676
TBL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09733
TNFRSF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46944
PPP6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91081
Pancreas	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.781213
chr7_74878823_T_C_b38	GTEx eQTL 2025	1.0	1.0645
PINLYP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69002
SNRPD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69454
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6303
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9168
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6319
DLGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61137
PROX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8178
RALB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15038
PDE6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21466
DCTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89637
MMADHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11369
ARRDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46961
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1545
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	113.009
SRSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52344
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3278
NOL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07193
EHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22602
NAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42955
TRMT12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24623
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5831
GADD45GIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07577
FBRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86966
FOSL1::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.589
MITF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43438
GCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12268
CDCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24614
ITCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39979
HEXD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87697
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8509
GPR37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0155
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.396
ZNF274	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5833
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8898
REM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14913
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5482
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.20024
RAG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03174
FOXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14649
HOXB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69484
TKFC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49603
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	294.876
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8486
GSPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98969
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3698
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6907
ATR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83225
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2821
MRPS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00475
COL16A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62378
PYDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26057
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.154
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5655
DCUN1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04212
GSE213228_2_v_3_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_8_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
CLASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06428
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7576
GSE143944_2_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4391
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3186
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	134.01
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.023
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1728
CDKN1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77662
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.4646
496100349_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03852
ACOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26849
GSE160817_0_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210476_9_v_3_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPP2CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07474
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CLDN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24594
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.6089
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1604
CCDC153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52988
EEF1E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30627
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9529
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
NMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76696
ALG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.187
PAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1649
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4659
KDM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37442
RPL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39062
chr7_74964270_C_T_b38	GTEx eQTL 2025	1.0	1.00189
SAP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02174
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPACA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12922
DKC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59476
GSE128563_2_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73811
ARMCX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50817
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3281
FOXC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08637
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6604
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.343
DAXX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41067
PRKAR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80875
POLG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4965
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4147
GSE242083,GSE242098_2_v_5_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SCOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.30805
NR2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11571
TMEM132B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79562
RBBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.089
496100358_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08622
ATP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23321
UACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0155
GALNT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18905
RRP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32051
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9767
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9387164-Table_2.XLSX-Sheet1-CLOCK_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
DLD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25942
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1123
DCAF12L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12837
PAXBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43205
BANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2063
NDUFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11051
GSE236504,GSE236505_0_v_1_atmin_human	RummaGEO Gene Perturbation Signatures	1.0	null
ANKRD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45422
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6015
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2524
496100365_HIP_probable Alzheimer's disease_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42118
EIF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19318
FAAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42757
496100386_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26174
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6702
GTF2E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04282
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.632
TJP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47703
ZNF492	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77577
DOCK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79497
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7307
CACTIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33738
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.475
PPP1CB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18724
ATAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44099
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.4152
SLC39A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2916
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1647
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6885
GSE214931_1_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UTP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77894
SHISA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08691
MACROH2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40905
CCDC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43574
ZXDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26145
TBCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20449
TMEM223	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58894
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08873
ZCRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38369
HOXD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63089
STBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35357
Progesterone-mediated oocyte maturation	KEGG Pathways 2026	1.0	null
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF683	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34952
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8695
496100443_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.44502
FOXD4L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10836
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6772
CERK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65571
ZNF830	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07425
GSE130396_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1511
496100373_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.02027
OTX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1563
MCM3AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32819
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1384
WDR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22451
NFYB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45697
chr7_74922518_G_A_b38	GTEx eQTL 2025	1.0	1.09044
NRXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10057
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.7475
PHF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81288
chr7_74954504_C_T_b38	GTEx eQTL 2025	1.0	2.41005
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5023
ERCC6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14064
GSE233183,GSE233187_2_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0395
TMEM86A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31676
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6909
CALB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38775
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
KCNIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1853
FBXO30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05736
ATRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76559
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1056
PSMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44909
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6348
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
HMGB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56403
SOGA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84034
GSE189772,GSE189773_0_v_5_fbxo11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7661
496100646_TCx_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.18671
ICAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28883
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148200_3_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7779
AIRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32354
PRAME	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17934
SBDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58945
chr7_74985989_A_G_b38	GTEx eQTL 2025	1.0	1.42932
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3164
CTDSPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93333
ZNF577	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29676
GINS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58825
496100639_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.80382
GSE160817_3_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
HEATR5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41119
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTF3C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14152
GSE160817_2_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
FARP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23829
IRF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.3489
CARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31956
ANKRD33B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48262
CHTOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24802
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
CCNJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5458
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.6687
ATF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51094
MRPS18C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28416
ZBED1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2148
PAAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43364
CIAPIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00344
BCL2L12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23529
ZNF614	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23718
RRN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88206
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.1428
HSPA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93624
PLXNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86643
HNRNPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35782
ATF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6504
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6262
MOB1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16403
HSPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48875
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5354
PTPN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98953
DDX21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09039
PHOX2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02352
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.7432
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.7708
PFDN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86065
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19429
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.5879
CASD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29688
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2356
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7374
GOLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5978
NLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.953
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4742
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5838
HNRNPCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63707
CHAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44451
RTEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32132
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.781213
SYNRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02809
GSE186739_0_v_1_asic3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0958
SDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27517
RNF135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01278
DCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90521
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5246
C10orf88	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49738
496100451_TCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.1573
RIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26
POGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27353
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.7301
PITX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4526
VHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70521
MATK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13112
LARP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04268
MED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58361
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71872
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8259
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80597
PRAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38597
TULP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17944
GLIS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92282
chr7_74885662_A_G_b38	GTEx eQTL 2025	1.0	1.27421
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2254
chr7_74882048_A_T_b38	GTEx eQTL 2025	1.0	1.08412
SPPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21376
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04764