association	dataset	threshold value	standardized value
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980411
ZNF597	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00691
COA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34234
AMO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6644-01A-21R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD83	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7158
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16723
Crouzon syndrome-acanthosis nigricans syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.891
MAFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74579
CNOT6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40383
ZC3H7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4411
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCEAL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55393
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RQ-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7727-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Seborrheic keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
Brain Lower Grade Glioma_LGG_TCGA-HT-7686-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A7D7-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kinase binding	GO Molecular Function Annotations 2025	1.0	null
PLEKHG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06449
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1262
ZNF233	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91112
small intestine	GTEx Tissue Gene Expression Profiles	1.0	0.940661
SLC6A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84205
KELLY	DepMap CRISPR Gene Dependency	1.0	2.43596
ZNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98484
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7901
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I7-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5996
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE108500_1_v_0_foxp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GABBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50826
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RO-01A-12R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDST8	DepMap CRISPR Gene Dependency	1.0	5.52993
Brain Lower Grade Glioma_LGG_TCGA-HT-A618-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8589
OVOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42741
HERC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51008
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A7UZ-01A-12R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63T-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUDHL1	DepMap CRISPR Gene Dependency	1.0	2.43877
AML193	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39784
WT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2081
Prostate adenocarcinoma_PRAD_TCGA-CH-5750-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FADD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80302
Liver hepatocellular carcinoma_LIHC_TCGA-BC-4072-01B-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6987-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB436	CCLE Cell Line Gene CNV Profiles	1.0	2.27625
MPV17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68554
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5325-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.96652
KCTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69071
endometrium	HPA Tissue Protein Expression Profiles	1.0	1.61065
KDM6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48368
NPIPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68293
RT112	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36879
EPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96055
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0937
SMAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74006
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF524	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08161
TTLL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05207
SOX17_01_300	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	4.03467
GSE128730_4_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Heroin dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.898
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-94-7943-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acanthoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
TFEB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8717
PRKAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64492
NCIH1755	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92825
Uterine Carcinosarcoma_UCS_TCGA-ND-A4W6-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10176
Lung adenocarcinoma_LUAD_TCGA-95-A4VP-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gallbladder	HPA Tissue Protein Expression Profiles	-1.0	-0.776622
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100295_TCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.12043
POMGNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21545
FAM177A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63757
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4725-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91032
TRIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7488
Lung squamous cell carcinoma_LUSC_TCGA-60-2703-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3794
SP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07916
SCAI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84631
Lung adenocarcinoma_LUAD_TCGA-93-A4JQ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10752
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4114
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4162-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81711
PAPLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44493
ASS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77886
496100324_FWM_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4096
Brain Lower Grade Glioma_LGG_TCGA-FG-A87Q-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.946039
Lung squamous cell carcinoma_LUSC_TCGA-85-A50Z-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63529
NDUFS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91066
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52W-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SEM	DepMap CRISPR Gene Dependency	1.0	2.75626
Sperm flagellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.244
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.836844
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43943
P4E6	DepMap CRISPR Gene Dependency	1.0	2.61308
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.3994
SNU738	CCLE Cell Line Gene CNV Profiles	1.0	2.18685
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08508
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73E-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BET1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68098
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54287
YD8	CCLE Cell Line Gene CNV Profiles	1.0	1.52731
ACVR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26718
WPE1NA22	DepMap CRISPR Gene Dependency	1.0	2.42538
HDQP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77334
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5196-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02364
DYNC2I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55305
Brain Lower Grade Glioma_LGG_TCGA-DU-6406-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100497_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40706
ICC9	DepMap CRISPR Gene Dependency	1.0	7.71021
Brain Lower Grade Glioma_LGG_TCGA-CS-4942-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nuclear exosome targeting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.01
TM31	CCLE Cell Line Gene CNV Profiles	1.0	1.62795
Lung squamous cell carcinoma_LUSC_TCGA-85-8052-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PNMA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37753
B800-820 antenna complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.993
GSE188721_2_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5263-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153354_0_v_1_tcf19_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69167
MDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44617
Lung adenocarcinoma_LUAD_TCGA-44-A4SU-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45W-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epididymis	HPA Tissue Protein Expression Profiles	1.0	1.61065
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A9FH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
ACSM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81546
MDAMB361	DepMap CRISPR Gene Dependency	1.0	2.8551
NCI-H1703	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A677-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNRPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56577
ZNF423	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02657
ATP6AP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9347
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19709
Lung adenocarcinoma_LUAD_TCGA-44-2666-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53C-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MP-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Y79	DepMap CRISPR Gene Dependency	1.0	2.85883
MZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.466
DEAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09483
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7388-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1485
CDCA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50633
Sarcoma_SARC_TCGA-DX-A6YQ-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SK-N-AS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29787
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3323-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1105	CCLE Cell Line Gene CNV Profiles	1.0	1.77967
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.70586
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7404-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCNF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89472
ZFTRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89925
PFEIFFER	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34298
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95795
KMS34	DepMap CRISPR Gene Dependency	1.0	2.00927
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14858
NCIH522	CCLE Cell Line Gene CNV Profiles	-1.0	-2.13078
Brain Lower Grade Glioma_LGG_TCGA-DB-5275-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-4613-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7235-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-4077-01B-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A6-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100586_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05302
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M8-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81T-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.7637
MPND	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.23914
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EH-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4859-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52159
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.91032
DDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16364
HCE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
spleen	HPA Tissue Protein Expression Profiles	-1.0	-0.776622
M6PR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28552
RMGI	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37831
K-562	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AG-3902-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.185
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC70	DepMap CRISPR Gene Dependency	1.0	2.25594
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5590-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4487-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BAIAP2L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68041
Progesterone-mediated oocyte maturation	KEGG Pathways 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980411
Lung squamous cell carcinoma_LUSC_TCGA-66-2744-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB7	DepMap CRISPR Gene Dependency	1.0	3.53017
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71U-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848709
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-A8OW-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.9386
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GR-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
adrenal gland	GTEx Tissue Gene Expression Profiles	-1.0	-1.02245
seminal vesicle	HPA Tissue Protein Expression Profiles	1.0	1.61065
WAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10158
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08508
EID2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39032
Lung squamous cell carcinoma_LUSC_TCGA-22-1011-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ECGI10	CCLE Cell Line Gene CNV Profiles	1.0	2.14833
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3426-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HF-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0004
DUS4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59294
RASL10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67902
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26703
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4CG-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANKRD23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27075
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1589
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0004
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JV-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7885-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6VC-01A-23R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68729
CTNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72746
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RG-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6146-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MPV17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51393
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.840824
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980411
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206729_2_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RCHACV	DepMap CRISPR Gene Dependency	1.0	5.07678
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7875-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21381
Bladder Urothelial Carcinoma_BLCA_TCGA-K4-A3WU-01B-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
P2RX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7402
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.39095
SLC1A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02413
MTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26628
Substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
CIRBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18925
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10487
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A5PC-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LU135	DepMap CRISPR Gene Dependency	1.0	2.17329
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5462-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.776622
CDK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96296
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2087	CCLE Cell Line Gene CNV Profiles	1.0	1.598
NFIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85895
PIDD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25554
ZHX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04641
496100466_PCx_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.05466
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32094
SHISA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47705
OLFML2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90726
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08508
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3455-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM219B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8895
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48334
JAR	DepMap CRISPR Gene Dependency	1.0	4.73241
appendix	HPA Tissue Protein Expression Profiles	-1.0	-0.776622
KG1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3447
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GH-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDLBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08907
NFYB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1348
Lung adenocarcinoma_LUAD_TCGA-55-7728-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91358
RERFLCAD1	DepMap CRISPR Gene Dependency	1.0	2.52465
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.9833
Lung squamous cell carcinoma_LUSC_TCGA-56-8503-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100460_TCx_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52385
Rectum adenocarcinoma_READ_TCGA-EI-6885-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2066	CCLE Cell Line Gene CNV Profiles	1.0	1.33209
Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7300-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6870-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7828-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pfeiffer syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.083
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAB39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76903
Crouzon syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
ZNF527	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55249
H2AC19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47255
Lung squamous cell carcinoma_LUSC_TCGA-33-4547-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
small intestine	HPA Tissue Protein Expression Profiles	-1.0	-0.776622
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08508
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8314-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6980-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lung	GTEx Tissue Gene Expression Profiles	1.0	0.952986
Lung adenocarcinoma_LUAD_TCGA-50-5933-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8405-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF260	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67873
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EG-06A-12R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852788
COV413A	DepMap CRISPR Gene Dependency	1.0	2.73724
Attention deficit hyperactivity disorder	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.622185
Kidney Chromophobe_KICH_TCGA-KL-8339-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RP-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	1.36755
SNW1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33929
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25269
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.54184
kidney	HPA Tissue Protein Expression Profiles	1.0	0.881523
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U1-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oral mucosa	HPA Tissue Protein Expression Profiles	-1.0	-0.776622
NAIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3737
RB1_KD_GSE50532_623_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
VAX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70696
Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU886	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45049
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.7884
ZNF460	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.802
TMEM191B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16763
TGW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2086
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3513
CHPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70207
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HH-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC35E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3758
Lung squamous cell carcinoma_LUSC_TCGA-66-2737-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9412
SPEN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96379
KMS-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9163
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80O-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LC1SQSF	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77614
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882462
REXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63354
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5869
EDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40896
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.836844
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YJ-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100495_FWM_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21494
IGF2BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12623
Oocyte meiosis	KEGG Pathways 2026	1.0	null
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22412
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0961
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4857-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GPX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52893
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MA-AA41-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852788
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A6RY-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CFAP298	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50696
TRMT61A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79567
GOLGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82395
Plasma membrane light-harvesting complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.756
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43943
Lung squamous cell carcinoma_LUSC_TCGA-98-8020-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.13661
496100444_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60035
Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPP3R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11573
SNU601	CCLE Cell Line Gene CNV Profiles	1.0	1.36825
MAP3K9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62736
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7508
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RV-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.8808
BHLHE40	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7447
Pancreatic adenocarcinoma_PAAD_TCGA-3E-AAAY-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW900	CCLE Cell Line Gene CNV Profiles	1.0	1.53218
RTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60959
vagina	HPA Tissue Protein Expression Profiles	-1.0	-0.776622
EIF2B5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42913
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-17p13_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6996-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF768	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	67.7929
Acute Myeloid Leukemia_LAML_TCGA-AB-2964-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DNAJC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71075
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5454-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS821T	CCLE Cell Line Gene CNV Profiles	1.0	1.47445
light-harvesting complex, peripheral complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.851
ISOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94197
MXD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45704
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2968
496100351_FWM_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30925
CTAGE6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9923
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.852788
TMEM86B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53277
PMC8600817-12951_2021_1120_MOESM2_ESM.xlsx-Table_S4-Table_S4_Pan_PPAR-iMSC-EV-induced_differentially_expressed_genes_in_fatty_acid-treated_HepG2_cells_PPARA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Arterial tortuosity syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
Acute Myeloid Leukemia_LAML_TCGA-AB-2938-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
YIPF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26022
MXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5169
BHLHA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53303
CAL851	CCLE Cell Line Gene CNV Profiles	1.0	1.44263
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26956
ovary	GTEx Tissue Gene Expression Profiles	-1.0	-2.10021
Lung squamous cell carcinoma_LUSC_TCGA-63-A5ML-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC16A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15572
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.76049
DZIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83222
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835537
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A7CZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NK-A5CX-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100366_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.82788
Lung adenocarcinoma_LUAD_TCGA-86-8076-01A-31R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4843-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Behcet's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.09
EIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88651
SUM 159PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38942
496100400_PCx_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06156
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882462
POLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13471
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.57166
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.776622
PMC7880998-41467_2021_21255_MOESM8_ESM.xlsx-Sup_Data_5_TWIST_Panel-Gene_Name_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
KCL22	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94831
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1165
Opiate dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.612
Brain Lower Grade Glioma_LGG_TCGA-S9-A89V-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO678	DepMap CRISPR Gene Dependency	1.0	4.35714
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34936
BTBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7711
Cell cycle regulatory protein, Spy1	InterPro Predicted Protein Domain Annotations	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-A8P0-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DIS3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22303
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.776622
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19859
Adrenocortical carcinoma_ACC_TCGA-P6-A5OF-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66974
CLDND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9804
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5117-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7XO-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34007
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COX6B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26079
CDC42BPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1989
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48984
Lung squamous cell carcinoma_LUSC_TCGA-58-8390-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82246
liver	HPA Tissue Protein Expression Profiles	1.0	1.61065
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71B-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A8O5-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
496100518_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.94045
SEMA4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22196
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5523
Lung adenocarcinoma_LUAD_TCGA-64-5779-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Childhood pilocytic astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
TFEC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8225
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882462
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A3Z1-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fallopian tube	HPA Tissue Protein Expression Profiles	-1.0	-0.776622
KO52	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70773
Lung squamous cell carcinoma_LUSC_TCGA-33-A5GW-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ICC106	DepMap CRISPR Gene Dependency	1.0	4.35379
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4842-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3009-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8007-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07848
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OQ-11A-21R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OP-11A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ME1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65329
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51T-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.49148
GSE139455_2_v_3_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JX-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6849-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW756	DepMap CRISPR Gene Dependency	1.0	2.02649
RC-K8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-0.776622
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6488-01A-12R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91323
SAP30	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3357-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4723-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7573-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGM2_KD_GSE23702_713_human_NB4 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1187
protein kinase binding	GO Molecular Function Annotations 2025	1.0	null
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57542
CLEC2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81824
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2391
AHCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.347
Plasma membrane-derived chromatophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.719
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A8HT-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A780-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCS2	DepMap CRISPR Gene Dependency	1.0	3.2909
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.18193
H376	DepMap CRISPR Gene Dependency	1.0	2.86476
Muenke Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.259
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3VY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FASTKD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60978
RNF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49322
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05634
MAPKAPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26128
Lung adenocarcinoma_LUAD_TCGA-86-8672-01A-21R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM135A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5834
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34007
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02364
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4335-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6V9-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70778
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4781-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49011
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-01A-31R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26703
cervix, uterine	HPA Tissue Protein Expression Profiles	-1.0	-0.776622
Lung squamous cell carcinoma_LUSC_TCGA-34-7107-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936223
ZBTB7C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8237
CALHM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44369
DNAAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88968
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02364
Lung adenocarcinoma_LUAD_TCGA-50-5066-02A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.614
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5652
FOXJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82081
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6072
SURF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24453
Drug dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.405
TNFSF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81752
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.822
QPRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24094
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO783	CCLE Cell Line Gene CNV Profiles	1.0	1.36022
Lung squamous cell carcinoma_LUSC_TCGA-34-8454-11A-01R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.491
NCIH1648	DepMap CRISPR Gene Dependency	1.0	2.89568
OSGIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78331
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38942
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.13956
Lung adenocarcinoma_LUAD_TCGA-97-7552-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RDH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4565
SNU16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50018
Acute Myeloid Leukemia_LAML_TCGA-AB-2944-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04203
SUPT1	DepMap CRISPR Gene Dependency	1.0	6.89917
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U2-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MU-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02719
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.00538
PTK7_knockdown_185_GSE50138	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.61787
Lung squamous cell carcinoma_LUSC_TCGA-56-A49D-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90326
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42P-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835537
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10752
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.85801
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.9163
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6010-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70G-01B-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FAM72B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71919
ECHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28919
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19707
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
duodenum	HPA Tissue Protein Expression Profiles	-1.0	-0.776622
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43943
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MD-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4004
Brain Lower Grade Glioma_LGG_TCGA-DU-6397-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-L3-A4E7-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4081-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OACM51	DepMap CRISPR Gene Dependency	1.0	3.13232
FAM200B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85509
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34007
SF268	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.59221
METTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75791
JHH-7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MRK-NU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00176
TBX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91655
CHOP-C/EBP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.389
KNS60	CCLE Cell Line Gene CNV Profiles	1.0	2.64141
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.8588
RD	DepMap CRISPR Gene Dependency	1.0	3.52658
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4888-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7393-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOKUG	DepMap CRISPR Gene Dependency	1.0	3.62457
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6912
BJAB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34007
UMUC5	DepMap CRISPR Gene Dependency	1.0	2.86248
L3MBTL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72269
PANC1005	DepMap CRISPR Gene Dependency	1.0	5.02763
TNFRSF21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46944
TMEM249	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78058
GSE125219,GSE125221_5_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81412
cerebellum	HPA Tissue Protein Expression Profiles	1.0	1.03219
H3K4me1_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZXDB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3922
RL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48984
KINGS1	DepMap CRISPR Gene Dependency	1.0	3.53362
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A97K-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04203
DNAJB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85699
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BE-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
C17orf80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81959
TNRC6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42013
IRF2	JASPAR Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RK-02A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SAP130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74503
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7376-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
THP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67005
KMS27	DepMap CRISPR Gene Dependency	1.0	4.10894
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5680-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.662
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6989-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TYSND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63663
Brain Lower Grade Glioma_LGG_TCGA-FN-7833-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835537
ARL4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56362
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45983
Rectum adenocarcinoma_READ_TCGA-AG-3732-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D5-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EX-01A-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2704-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IK-01A-32R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6826-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z9-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.834
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10S-01A-22R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IZUMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20174
MDAMB453	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67218
Lung squamous cell carcinoma_LUSC_TCGA-85-7950-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549	CCLE Cell Line Gene CNV Profiles	1.0	1.36301
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
ST486	DepMap CRISPR Gene Dependency	1.0	3.55379
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30368
Lung squamous cell carcinoma_LUSC_TCGA-77-A5FZ-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3319-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5378-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DCBLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02665
KYSE-220	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-6691-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OAW-28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DNAJB12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54798
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PF382	DepMap CRISPR Gene Dependency	1.0	7.3353
PAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29069
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6005
GSE168797_1_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.836844
Intercalated disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.305
CAPRIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06399
JEKO-1	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.24687
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955873
ECEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.878
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43524
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1197
Acute Myeloid Leukemia_LAML_TCGA-AB-2993-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLNC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71467
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.681
TMEM221	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31419
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.699
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ICC108	DepMap CRISPR Gene Dependency	1.0	2.76288
TMEM120B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15158
KANSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66098
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8625-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62872
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.12227
salivary gland	GTEx Tissue Gene Expression Profiles	1.0	1.31286
CADM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79059
PPP1R18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66802
PMM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31839
Lung adenocarcinoma_LUAD_TCGA-MP-A4SW-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
SKHEP1	CCLE Cell Line Gene CNV Profiles	1.0	1.41388
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.2097
Bladder Urothelial Carcinoma_BLCA_TCGA-R3-A69X-01A-22R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
CALU6	CCLE Cell Line Gene CNV Profiles	1.0	1.39514
GSTK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57886
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EU-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RB1_KD_GSE50532_627_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8350-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27284
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAXX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36064
Rectum adenocarcinoma_READ_TCGA-AH-6544-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96343
NCI-H1048	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.59221
Brain Lower Grade Glioma_LGG_TCGA-FG-A710-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF428	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57471
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBE2J2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47384
PPCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89705
PRIMPOL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07527
L428	CCLE Cell Line Gene CNV Profiles	1.0	1.47658
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49066
Kidney Chromophobe_KICH_TCGA-KM-8476-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NALM6	DepMap CRISPR Gene Dependency	1.0	2.70255
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A684-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7910-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZDBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61645
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.19709
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A2OS-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ECE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62606
RAB24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50917
Uterine Carcinosarcoma_UCS_TCGA-N5-A59F-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3MB-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100426_PCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.60683
thyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-0.776622
ECI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69768
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NK-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.1477
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A6HN-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHAGOK1	DepMap CRISPR Gene Dependency	1.0	4.52981
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VV-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.980411
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3125
ZNF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89731
P31FUJ	DepMap CRISPR Gene Dependency	1.0	2.45994
Lung adenocarcinoma_LUAD_TCGA-NJ-A55O-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33191
NB7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Zona reticulata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.401
USP6NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31602
Lung adenocarcinoma_LUAD_TCGA-91-6840-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6030-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2887
SU-DHL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49066
PAX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7315
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H1-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68552
ANKRD13D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33042
C10orf105	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30867
MFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96321
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K7-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29643
SNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08996
SW156	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848709
ZFYVE19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75053
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2943
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936223
TFK1	DepMap CRISPR Gene Dependency	1.0	6.74209
SNU1079	CCLE Cell Line Gene CNV Profiles	1.0	1.59181
Rectum adenocarcinoma_READ_TCGA-CI-6619-01B-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A4PA-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IE-01A-21R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 05.04	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65392
PE/CA-PJ15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936223
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6970-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.80205
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.835537
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54287
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70K-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFE3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2056
KASUMI6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38237
SNX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75372
ZNF135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89956
H3K27me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZSCAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21747
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	1.0	2.88056
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
Fetal Lung	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	2.44474
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.496
Hallux	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.762
BMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51158
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.42777
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M5-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4650-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NCIH889	CCLE Cell Line Gene CNV Profiles	-1.0	-2.34778
PATU8902	DepMap CRISPR Gene Dependency	1.0	4.26079
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10752
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1409
PPP1R35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82052
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U3-06A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLR26	DepMap CRISPR Gene Dependency	1.0	2.15336
CAOV3	DepMap CRISPR Gene Dependency	1.0	2.55452
Stomach Smooth Muscle	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.24883
ADCY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81167
SKMG1	DepMap CRISPR Gene Dependency	1.0	2.09549
EPHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38867
HUO9	COSMIC Cell Line Gene CNV Profiles	1.0	2.15316
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2596
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-UC-A7PF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2535
Adrenocortical carcinoma_ACC_TCGA-PA-A5YG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLB985	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5360-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUPM2	DepMap CRISPR Gene Dependency	1.0	3.00406
SAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99589
MARCHF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1057
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3955
NUDT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95203
POLR2J2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14048
VAESBJ	DepMap CRISPR Gene Dependency	1.0	2.2766
BICD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15661
KMS11	CCLE Cell Line Gene CNV Profiles	-1.0	-2.68854
CEP57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12064
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54I-01A-21R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SLC27A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02024
Rectum adenocarcinoma_READ_TCGA-F5-6571-01A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLVCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8669
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2086
NECTIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50243
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.1444
ATP5F1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88918
Lung squamous cell carcinoma_LUSC_TCGA-58-A46L-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A763-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A913-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LIMK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97895
Pancreatic adenocarcinoma_PAAD_TCGA-S4-A8RP-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15006
SYMPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75388
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29643
REH	DepMap CRISPR Gene Dependency	1.0	3.56882
Lung squamous cell carcinoma_LUSC_TCGA-52-7622-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13269
JOSD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17368
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.54331
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0259
TSPYL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57952
MAFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4742
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34007
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2086
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DMS-53	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5751-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8386-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tonsil	HPA Tissue Protein Expression Profiles	-1.0	-0.776622
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11588
HCC827	CCLE Cell Line Gene CNV Profiles	1.0	1.63706
Acute Myeloid Leukemia_LAML_TCGA-AB-2879-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A76L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LV-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-W3-A825-06A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7ME-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SISO	DepMap CRISPR Gene Dependency	1.0	3.90178
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5517
COLO680N	CCLE Cell Line Gene CNV Profiles	1.0	1.63271
NKX2-4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8952
MTRF1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47325
496100385_TCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2569
TOMM40L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64408
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR3E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84324
PLCG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1979
TEKTIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02369
KYSE30	CCLE Cell Line Gene CNV Profiles	1.0	1.62835
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A67X-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7372-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100422_TCx_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.73888
RNF146	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71855
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07848
JPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02358
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.6631
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7590-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7802
Lung adenocarcinoma_LUAD_TCGA-91-6830-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955873
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.848709
MPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65865
RHOXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90131
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74727
Brain Lower Grade Glioma_LGG_TCGA-KT-A7W1-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNG11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45212
NCIH1792	CCLE Cell Line Gene CNV Profiles	-1.0	-1.328