association	dataset	threshold value	standardized value
DDX20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6882
NAA16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73448
GSE193588_1_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34105
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8158
RNF122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.778
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.6013
RNF214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.141
EAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01171
TCL1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6009
MACIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46109
LYPLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60981
FIGLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20187
Lhx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6828
PMC8481886-Table_1.xlsx-A_subsets-UC_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
LIMK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03114
PMC5444746-oncotarget-08-30328-s002.xlsx-SI01_ChIPSeq_H3K9me_AR-Gene_Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.84306
ACSM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49452
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-1n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.9511
RBBP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.089
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
UBR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09696
PRPF38B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62085
POU6F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0418
PPP2R2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16122
NR1I3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0254
TGFBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82818
DDX41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4417
Fulvestrant_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00864774
ZEB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4997
PGRMC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65435
GSE199541_2_v_4_mbd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AGPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57895
TKT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54736
TRIM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88817
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.5736
Prdm14	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.4919
ZEB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03325
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.1727
DAZAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73148
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RAB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54239
MITF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3213
ZNF177	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35904
496100314_HIP_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06935
ARL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90202
GSE214931_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
IL27RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44958
SOWAHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8585
SHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52848
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07232
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.5998
ANAPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20518
Fruit consumption	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.13979
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08246
GSE144919,GSE145177_1_v_0_dazl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80555
HLTF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.24041
GSE131161_1_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210662_2_v_1_znf165_human	RummaGEO Gene Perturbation Signatures	1.0	null
PLEKHJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03258
Oxaliplatin_PANC-1	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0059602
USP21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55792
GSE183994_1_v_0_scml2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE113817_2_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NOL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06877
BANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2063
TM9SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30921
GSE217452_3_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5254
GTF3C3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1638
SPG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30708
HSPA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57546
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66044
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5312
GSE148252_1_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DNAJC30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78103
ZNF546	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76627
HMGCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38083
PAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28707
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09468
TMEM268	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27865
CEP135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08248
CCDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54678
NSFL1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90264
GSE211286_4_v_3_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DSEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0223
RAMAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02328
ZSCAN25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15628
TTLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77435
PMC5055179-CAM4-5-2522-s008.xlsx-S1-Supplementary_Table_S1_Properties_of_genes_upregulated_by_MBD-TET1-CDwt_TET1	Rummagene Transcription Factor Associations 2026	1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9791
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.5429
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FBN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54595
CSTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53117
PRICKLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62038
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
SARNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52877
ZC3H11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18567
IGF2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66289
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.0087
GSE148252_7_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FLT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28591
PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Unnamed_4_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
TSEN54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29179
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3814
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
RALY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41812
JARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34813
ZBTB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25509
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3535
Gemfibrozil_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0172109
FOXH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1693
TRIP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60481
GABPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1723
TUBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04856
GSE219195_0_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157894_2_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCNG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30041
DDX43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89325
Retinoic acid_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0114616
GSE180185_7_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIM16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30105
DCAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58244
UBE2G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88604
PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
TIMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03033
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2675
GSE126776_0_v_1_pelp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
UTP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25922
HSF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1012
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Everolimus_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0218923
TRUB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66759
Dorzolamide (hydrochloride)_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0213512
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7703
PMC7445411-CPR-53-e12862-s006.xlsx-Sheet1-Supplementary_Table_S4_Gene_expression_profiling_of_NT-MSC_and_III-MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
496100632_HIP_no dementia_TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08885
C19orf84	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00858
ADPRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68108
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-SYMBOL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
ABT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54274
NUBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00056
GSE90754_0_v_1_foxo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4244
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8587
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6133
USP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18432
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5434
GSE110178_4_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.637
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125025_2_v_3_lyl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39063
GSE228261_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
CP21R7_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0203487
CCDC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48782
GSE229698_1_v_2_traf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GPR27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29221
GSE171572_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM151B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20176
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.16447
496100659_PCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.22316
USP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51671
GSE116354,GSE117379_2_v_4_cox2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110178_2_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5444746-oncotarget-08-30328-s002.xlsx-SI02_Gene_symbols-1912_ChIP-Seq_H3K9me1_2_demethylation_and_ChIP-Seq_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GPX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13051
Atoh1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.6225
RPL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02867
SLC66A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18322
PFDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91072
OLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41588
PSMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29567
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_1_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
EFCAB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33162
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
EFEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50445
PHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11386
PELP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62367
PRDX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69769
PMC12178937-mmc6.xlsx-L_AKAP12_KDvsD_AKAP12_KD_deg_al-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HMBS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35397
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.12781
PTBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04104
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-geneName_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
KIAA0232	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03949
H2BC15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07314
PTPRJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30804
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4454
NDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37004
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7631
PMC3376834-emmm0004-0052-SD2.xlsx-NR2E3_Specific_1847-Unnamed_1_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4913
GMPPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24711
REEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5399
Tubulin inhibitor 6_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0232897
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4547
ZNF808	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58298
SKA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47899
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.38198
B4GALNT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23372
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
REC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82368
PITRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64718
TOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38178
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8909
GSE125862_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.20475
RANGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.36075
GSE237812,GSE237813_3_v_2_hmgb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211128_3_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06662
RASA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47658
GSE217783,GSE217784_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CLMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19887
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64483
MRNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41711
Gli2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.1878
SFT2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83546
NDUFB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32672
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SHISA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19031
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7889611-41467_2021_21346_MOESM10_ESM.xlsx-High_TSA_score_correlations-Supplementary_Data_6_Genes_with_expression_that_positively_correlate_with_a_high_TSA_score_in_AIRE_and_corneocyte-like_mTECs_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
RPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3174
NUP50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36938
Carbidopa (monohydrate)_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0209941
ZC3H15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31022
MICOS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90259
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
PDRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92321
GSE228894_0_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ESRRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75451
FLCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36491
GSE145323,GSE145324_1_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EVX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16297
nucleus	GO Cellular Component Annotations 2025	1.0	null
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-Genes_with_ATF3_combined_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226249_2_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12660214-Supplementaryfile1.xlsx-Genes_Human_with_ATF3-binding-ATF3_TGAYRTCA_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
PRRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82262
CHMP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1456
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100497_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.27965
ARFGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26921
KLHL42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98863
RPP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25655
Abemaciclib_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0193076
LRRC42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2123
H2AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86192
KRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45851
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.7933
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6375
CNFN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04028
LRRC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13017
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE171572_3_v_4_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9168
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.6789
DST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24893
GSE200214_0_v_2_mrgpra1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Zfp809	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	51.2703
FNTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10943
MANBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23918
LSM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31298
HTRA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26054
TUT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52414
RNF38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7628
GSE224969,GSE224971_0_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC25A15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12684
GSE167224,GSE168147_3_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYBL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73811
VIRMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2249
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0764
CNIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02672
GSE188870,GSE188871_0_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3775
STARD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29109
PFDN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.67591
TFDP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62502
ICE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48102
Bimiralisib_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0186048
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0548
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5474
SCNN1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63805
SEC14L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71511
NELFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04865
GSE101112_6_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BI-78D3_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0194584
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234289_3_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Paclitaxel_HOP62	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00584074
TROAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88963
NFKBIE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07175
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46807
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HERPUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03991
DENND4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69265
HSPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32775
CYC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16431
SMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61464
AHCYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15671
PRKCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20362
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6696
ZNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25239
HDDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25616
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8390644-41467_2021_25107_MOESM6_ESM.xlsx-Naive_BRG1-KD_significant-gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
TCEAL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02933
CCNH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13164
DNASE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05366
BHLHE41	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9889
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7962
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17628
LGI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30852
S-Adenosyl-L-methionine (disulfate tosylate)_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0182565
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5642
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9607
ACSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17276
UBR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06121
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.3316
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7621
MCRS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99814
GLIS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6388
GSE242199_6_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM115	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11845
NKX2-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9857
SUN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26121
GSE143994_2_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EHF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.558
DTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04954
ZSWIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57121
Quinestrol_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.018546
EXOSC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04569
TMEM30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28633
PMC11758349-11130_2024_1262_MOESM1_ESM.docx-4-RFXDC2_RFX7	Rummagene Transcription Factor Associations 2026	1.0	null
DENND4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.1622
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2025	1.0	null
TCF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4606
DCAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75133
Tazarotene_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0117748
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2425
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21984
GSE242199_9_v_11_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ISCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24109
Pentoxifylline_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0165016
PRICKLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31379
CYP26A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35174
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1112
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4289
SLC25A36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25371
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7059
MAPK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35964
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RHOA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14024
NUDT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00271
HLA-E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37929
BCL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77914
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29041
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16709
COIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21969
RNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25061
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.2967
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66063
SPATA2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14902
CEP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33009
DPY19L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35406
CHAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03981
GSE176008_0_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTTNBP2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0264
MRPL44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1832
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF433	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94717
NPIPA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06271
GCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06079
KIF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36369
PNPLA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60662
GSE157049,GSE157051_6_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Oleic acid_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0171968
DDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77711
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.4676
DPH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98545
ZNG1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92473
ZNF527	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03572
PMC8803621-mmc6.xlsx-Sup_Fig5A_genes_list-Genes_with_following_MEF2_motifs_around_their_TSS_CTAWWWATA_RSRFC4_Q2_MEF2_Q6_01_MEF2_03_MEF2_02_RSRFC4_Q2_from_GSEA_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
SLC29A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3003
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225218_8_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RNF31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80894
alpha-tubulin binding	GO Molecular Function Annotations 2025	1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03552
PMC11956947-media-4.xlsx-C_GSEA_gene_sets-TGAYRTCA_ATF3_Q6_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
EPCAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40051
PMC9999213-mmc1.xlsx-DEGs_vs_2D-DEA_NB_MSC_EC_CSc_vs_NB_2D_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
SP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38905
DNPEP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40426
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2707
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.5589
KAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82403
PYM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90139
NUP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05672
TRIB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14418
GAMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62628
ESRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87661
RPRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01528
tubulin binding	GO Molecular Function Annotations 2025	1.0	null
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18368
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PNMA8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84107
MEX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30203
CRLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7971
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
UNC5CL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55639
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5344
PMC7818749-12931_2021_1617_MOESM1_ESM.xlsx-TBX4-ENSEMBL_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
RAB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90802
TPD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7658
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CETN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00945
H3-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89653
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
TNFRSF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16117
PMC5577301-in-17-237-s001.xls-AR_downregulated_DEGs-Heart_GSE9377_GENE_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203308_8_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE185744,GSE185747_2_v_3_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
AKAP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2331
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.32322
NOP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40077
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CERS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29069
EIF2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02647
GBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22408
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE217552_3_v_2_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Capmatinib_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0106117
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.0
GSE145311_0_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H2BC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3251
AP3S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57165
GSE147056_4_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4564
496100488_TCx_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00309
PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
AUNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3116
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9482
FKRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23072
NOTCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99792
GSE214931_4_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE168807_6_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54906
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2068
PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
BI-3406_H4	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00485507
MMUT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47789
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0054
GSE131161_2_v_6_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NUBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79997
CDC34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02953
ZBTB18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1716
PSMB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19405
INO80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17552
PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Supplemental_Table_6_Genes_downregulated_in_NEUROG3-_-_hESC_line_differentiated_to_pancreatic_endocrine_progenitors_d13_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
FIBIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2134
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9383
TMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83715
TIMM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.15935
GSE77108_0_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.2229
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1043
PMC4212256-mmc5.xlsx-FLI1_log2_results-MIR622_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
SMG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80993
RSL24D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55011
PMC11214527-mmc5.xlsx-ADNP-gene_ADNP	Rummagene Transcription Factor Associations 2026	1.0	null
ZRANB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39771
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CARD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11531
MLXIPL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7676
THOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59575
XRCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60602
POLR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30877
ANLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58428
RAB1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37325