association	dataset	threshold value	standardized value
GSE158834_12_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAZ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.4743
BRD-K55662526	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04069
GSE149075_3_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K35975002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09617
GSE158834_2_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	181.977
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K43431234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05937
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K74486924	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07383
GSE57871_5_v_2_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87855
GSE169205_0_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K30491662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27183
MCF7_MLN8054_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0113447
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-combined_portrait-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_0_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K48389518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25702
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
3054_FECH_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.504028
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173997_3_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE184892_7_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE110178_5_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE183413_1_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73702
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9292
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE206226_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Esophagus - Muscularis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.767616
Gut microbiota relative abundance (Prevotella)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
BRD-K27347421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33992
GSE211128_9_v_8_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
CIAO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06232
BRD-K67036882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93879
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.4803
BRD-A80723361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36686
BRD-K15478481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82815
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K43053725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23777
BRD-K09960817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07593
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_6_v_12_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.4299
Golgi membrane	GO Cellular Component Annotations 2025	1.0	null
Apolipoprotein A1 levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.4301
GSE213588_10_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9802
TIGD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01699
BRD-K24070365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68108
GSE146612_2_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02268
GSE233679_12_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182680,GSE182683_7_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213588_8_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_3_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
NGLY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19769
GSE223609,GSE223610_0_v_2_kdm6a_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K22812176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20256
GSE214505_0_v_1_akr1b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE99112_0_v_1_upf3b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
6868_PSMD14_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.559965
BRD-K67980271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65461
BRD-K08995282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44034
regulation of SREBP signaling pathway	GO Biological Process Annotations 2025	1.0	null
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_11_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K45894579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.45587
10751_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.60068
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.6733
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ROBO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26278
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
3677_HEATR1_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.14112
BRD-K50700697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08557
BRD-A24223049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0499
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9886955-41420_2023_1325_MOESM12_ESM.xlsx-H6_14AvsH6_NC-Unnamed_2_HMX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K91506006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13659
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K59437706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60313
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEx Blood 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-3.15358
GSE111247_14_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K22940496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50007
GSE194396,GSE194429_2_v_3_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K96054771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03973
1197_CARS_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.525176
BRD-K23666684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16657
HDL cholesterol	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.769897
MCF7_IOX2_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148458
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151412_2_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.16995
GSE142210_2_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE203308_9_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11411
GSE103124_1_v_0_bmpr1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29018
BRD-K50445566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83168
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.9825
BRD-K05087650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04947
PMC11336098-41598_2024_70235_MOESM1_ESM.pdf-975-SP100_SP100	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K76008396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28066
GSE222758_0_v_2_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K53356402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38193
GSE131680_1_v_0_macroh2a1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TERT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00549
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	270.012
Vagina	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.661086
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.02742
BRD-K86050213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14245
GSE201309_4_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE207301,GSE207303_1_v_3_tp53bp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K85802892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52113
GSE92965_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A78042852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63494
DIAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22427
PMC6657958-pgen.1008250.s015.xlsx-ETS1_siRNA-Unnamed_0_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K95952081	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27415
GSE131649_6_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146982_3_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.733739
GSE149366_1_v_0_sulconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE234043_0_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K97236134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06241
BRD-K32862383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50771
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SETDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05476
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.5312
ABCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11343
GSE182835,GSE182836_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.737412
SURF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2613
BRD-K67177501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37804
GSE104508_0_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K39613696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05955
BRD-K80414383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14821
GSE229978_4_v_1_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K97242998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28773
GSE159049_3_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NUP160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08025
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEx Skin 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-12.8348
GSE234340_9_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8603
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K63757821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26703
BRD-K37637965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24937
BRD-A17635048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29417
BRD-K96106084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16266
BRD-A52377240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1864
ZC3H12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38871
ZSCAN5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92484
GSE111247_11_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE131649_6_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A07407288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65483
GSE190761_0_v_1_samd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206516,GSE206518_0_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE252857_1_v_0_prednisone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K39087188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23732
BRD-K04918285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27907
GMPPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04328
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
bounding membrane of organelle	GO Cellular Component Annotations 2025	1.0	null
GSE198794_2_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K41972460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35213
GSE226316_6_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169205_0_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
1464_CDYL_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.1816
GSE182680,GSE182683_0_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCAPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00603
GSE158834_0_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S3.xlsx-DAY1_SOX17_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.742
BRD-K65228230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18762
GSE155567_1_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180185_4_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.9796
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	189.003
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_0_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IFT20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82171
BRD-K76910883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13532
GSE148010,GSE148120_3_v_2_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_8_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE220613_0_v_1_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110178_5_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5B-Up_H3K4me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE116810_2_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
9424_TUBG1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.635643
GSE114284_2_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138468_3_v_6_dyrk1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150895,GSE150896_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K27398402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42887
BRD-K86358396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00884
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_2_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.05242
ABHD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00066
GSE193900,GSE193905_1_v_0_pura_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PYCR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11111
4043_IFITM3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.721267
BRD-K21296995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73355
GSE184892_0_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9393
BRD-K97462883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.30653
PMC7518873-abb0205_Table_S1.xls-TFEB_targets-symbol_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
MRPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36988
SKA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11697
BRD-K01512588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34021
BRD-K22065327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61366
BRD-A91823394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14975
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-down-Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE209598_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K97921950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02384
GSE151090_5_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE135030_3_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K16643911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21028
496100567_PCx_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10695
GSE186440,GSE186443_2_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE121319_1_v_0_gprc5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K50894381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59141
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4775
BRD-K78873216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02787
GSE217873_1_v_0_nusap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9803
GSE114284_1_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK4_unique_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K28623804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81606
GSE245418_0_v_2_cd109_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain - Hypothalamus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.7068
BRD-K79576342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19772
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.45985
BRD-K97332312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04475
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7181646-41523_2020_157_MOESM4_ESM.xlsx-RNAseq_KD_vs_Control_DEG-GeneName_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114284_2_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
11152_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.567815
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152246_0_v_1_dihydrotestosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178340_7_v_6_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K47349869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3502
PMC4082364-supp_ddu111_ddu111supp_table2.xls-Wilms3_WT1_SH-SI-48h_complete-Table_S2_shWT1_Wilms3_top_100_genes_up_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K73443280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07967
Six3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.4034
GSE129244_3_v_1_lmo2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131887_1_v_4_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K46897949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49544
BRD-K45819372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33665
GSE218907_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K11342801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.21574
GSE182680,GSE182683_7_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K19418944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20578
BRD-K67126097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.02814
GSE207863_0_v_1_hdac5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199255,GSE199356_6_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
positive regulation of SREBP signaling pathway	GO Biological Process Annotations 2025	1.0	null
BRD-K25226763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80436
GSE151689_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9314667-Table_1.xlsx-Regulons-HES6_HES6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K42400613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27406
MCF7_UNC0631_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132454
CRCGN015_MCF10A.TP53.M_24H:I07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.60915
BRD-K74391203	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75679
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12909
BRD-K87343552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29467
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.475
GSE219103,GSE219104_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K12106433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78023
BRD-K10876822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12798
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:A24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21963
PRMT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94588
BRD-K37774987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71004
BRD-K61681480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.38733
WASHC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93155
BRD-K96549574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86503
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8568
GSE184892_0_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K88224221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37587
GSE102870_7_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K34088127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37612
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_10_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149075_8_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154577_2_v_5_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE70499_3_v_1_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
8594_SUPT16H_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.542014
6720_PRDM10_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.532816
NSD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00634
BRD-K05137000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21286
BRD-K75252192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27034
ISY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24017
BRD-K92440102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53329
GSE149075_6_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158632_3_v_1_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE110178_5_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE151412_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCDC9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06176
GSE205021_3_v_1_fenofibrate_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.38212
BRD-K37253893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20882
BRD-K62795540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5011
GSE160246_2_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K41322154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88339
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27262
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE145171_0_v_1_prox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE190384,GSE190386_3_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18855
GSE201110_0_v_1_sirt4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K83670600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15843
PNPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57784
BRD-K36852613	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03257
GSE87299_2_v_3_nr1d1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NQO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80167
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.5014
GSE195713_0_v_1_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
8594_SUPT16H_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.531247
BRD-K49051633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26909
GSE70499_0_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K08409548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72056
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85315
BRD-K87158974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29392
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_2_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169205_3_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K48533326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11029
Creb5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.2064
BRD-K31536290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14064
BRD-K98772859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60622
GSE224157_3_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K47881755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82715
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A01848933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41075
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152432_5_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K32477623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90032
GSE115395_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100328_TCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.47703
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205540_2_v_3_phloridzin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GM2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16189
BRD-K81314458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33481
Neuroticism	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.909691
MCF7_Pelitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155884
GSE202434,GSE202438_8_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K64660038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1667
BRD-K49630774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50885
BRD-A28219573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.76027
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K51270604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22269
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40366
CRCGN011_HEPG2_24H:P07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12745
8222_SNRNP70_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.608939
GSE114284_4_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K81810589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25524
GSE158834_12_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LZIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34098
BRD-K16266179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16277
BRD-A26165232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32189
9680_UTP14A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.00749
BRD-K46726368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1566
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6858
GSE218060_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TRMT10C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57922
BRD-K31806725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12974
GSE203308_15_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K90801819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09879
2561_EIF4A3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.621896
GSE145639_1_v_6_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10274745-media-4.xlsx-S3B-Table_S3_Reanalysis_of_publicly_available_data_to_identify_AR_and_ER_direct_target_genes_related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K70116387	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36605
GSE149760_3_v_5_elof1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K42496940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14432
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4918
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.4047
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.592
CNDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50286
ACER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16779
GSE242083,GSE242098_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RNF149	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58651
GSE186647,GSE217288_11_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_12_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE163297_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K07755570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20535
BRD-K58846294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26175
GSE199255,GSE199356_3_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K87258738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09155
BRD-K14166090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04777
JKAMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34712
BRD-K20355073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34683
BRD-K17956418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80033
GSE220914_2_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.669
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.73025
BRD-K90806964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00645
BRD-K44003352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08625
BRD-K93615384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59814
BRD-K59120074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80372
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE113734_3_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K28140029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77528
GTEx Skin 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-11.0864
BRD-K86228587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01643
GSE198794_0_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A11350423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09475
GSE202434,GSE202438_3_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K98720112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1233
GSE197630_1_v_0_ruvbl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36586
NUFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30513
BRD-K68314790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03823
GSE48812_8_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169205_3_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE91015_0_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.10565
CRCGN015_MCF10A.TP53.M_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0239
GSE158834_11_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE155836,GSE155839_3_v_2_alvocidib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K56950366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08733
GSE70499_4_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cells - Cultured fibroblasts	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.7068
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52934
CRCGN010_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30543
496100352_FWM_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.27819
GSE213632_3_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152432_3_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K53547009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51389
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_11_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169356_2_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.10091
BRD-K88190816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02553
GSE151612_0_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE224742_0_v_1_slc1a5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE229973_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ABT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41145
GSE238018_1_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218879_1_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_10_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE207302,GSE207303_0_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218727_2_v_3_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K67314051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10551
BRD-K83300227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24685
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K50045638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26552
GSE226114,GSE226116_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K00530465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09425
GSE89018_11_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6928094-395_2019_765_MOESM7_ESM.xls-DEGs_AR7_vs_Pre-patterned-List_of_differentially_expressed_genes_in_AR7_vs_Pre-patterned_cells_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K74651253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.079
PMC9270251-mmc2.xlsx-4_Filtered_DEGs_Control_vs_KD_3-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.1901
GSE239844_6_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K81200901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33405
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN010_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2308
BRD-K79855662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20048
CRCGN015_MCF10A_48H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0884
GSE249098_1_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K47109712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72337
GSE158834_10_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211866_2_v_1_usp11_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158182_3_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112763,GSE112767_2_v_1_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1708
CRCGN015_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.751
BRD-K62909976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34624
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN011_HEPG2_24H:N20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11815
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE77795_2_v_1_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2849
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.1114
TRAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42066
TRAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40064
ATXN7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14535
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7739
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE235701,GSE261434_0_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE118766_2_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158632_3_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.9079
BRD-K59491389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55929
GSE84922,GSE84924_4_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K79521948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59026
CRCGN011_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.01205
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A97270959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37177
GSE158834_1_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K64072266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04543
BRD-K11089039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35672
GSE164874_5_v_6_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1561
GSE213588_9_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WDR77	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05198
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Meprednisone_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156817
PMC12209767-bcd-25-0099_supplementary_table_s2_suppst2.xlsx-C_DEGs_RNA-seq-Supplementary_table_S2C_List_of_differentially_expressed_genes_in_IGHUND_vs_IGH_GCB_MB2_DE_DLBCL_HGBCL-DH-BCL2_-BCL6_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K30761927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09848
BRD-K63058274	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63768
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	62.4
BRD-K36368568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08528
GSE211128_3_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130690,GSE130692_2_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K25465939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66781
CRCGN015_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.72621
GSE141143_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142588_2_v_0_cinobufagin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE118766_1_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149769_1_v_0_nlrp12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K69987634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16552
GSE199092_1_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK4_all_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K97170716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22476
BRD-K77504251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23178
CRCGN015_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.62595
TMEM245	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16604
GSE198165,GSE198166_8_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K84423439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39297
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0461
BRD-K42181022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96572
BRD-K36465335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19513
BRD-K97485956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05225
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE204784,GSE204787_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Thiotepa_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.017848
BRD-K39858575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.52308
GSE77108_0_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A14098586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06718
BRD-K22063616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57664
BRD-K39617634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49546
BRD-K65752097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97785
GSE182680,GSE182683_0_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE244710_1_v_0_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210101,GSE210114_7_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLFN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01819
GSE233679_12_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE143994_2_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_0_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE87615_1_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
8272_SON_P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.723569
BRD-K22701871	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87118
VCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86257
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-PAX6_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A89441445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24464
GSE70499_3_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_7_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7616986-EMS181817-supplement-Supplemenatry_tables.pdf-26-CLOCK_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5993422-NIHMS922534-supplement-Sup_Tables_1-23.xlsx-RELA-EnhancerAssociatedGene-Unnamed_3_RELA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K13085116	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35034
BRD-K17395396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28969
BRD-K10635555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24079
BRD-K88658905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03368
TRMT61A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29077
GSE216043_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K87080069	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64993
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE192771_2_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123105,GSE124556_0_v_2_pcf11_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K34024207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44872
HIRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15535
CRCGN015_MCF10A.TP53.M_24H:C03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11749
GSE70499_0_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.48105
GSE78199_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE166920_6_v_8_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.6537
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K12460566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20064
TTI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23491
GSE80098,GSE80366_0_v_5_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE94849_7_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0469
CRCGN008_HEPG2_24H:J18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1156
PMC12623973-41467_2025_64981_MOESM3_ESM.xlsx-downregulated-c0_ACKR4_SCS_ceiling_LEC_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195568_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	175.048
BRD-K87131514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01508
BRD-K79551673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43125
BRD-K08036779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.65517
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	129.497
BRD-A78355490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02247
GSE216043_10_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K21819164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.02462
GSE183606_1_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.6098
BRD-K33257311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47982
GSE190950_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_6_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K34524418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80896
GSE147664_0_v_1_arid1b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_0_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9225
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.18416
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.58275
BRD-K48611791	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29747
BRD-K30310320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11759
PMC12824906-mmc5.xlsx-Sheet1-Table_S4_Target_genes_of_FOXM1_and_their_expression_across_the_subtype_of_breast_tumors_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A30758703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74269
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_3_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE126463_0_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205729,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K91500340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27334
PMC9270251-mmc2.xlsx-2_Filtered_DEGs_Control_vs_KD_2-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE129389_0_v_6_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	110.255
BRD-K62935946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60869
BRD-K40266835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09681
CRCGN014_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2263
HDLBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43553
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.1421
GSE227891_5_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_9_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K61168922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19889
BRD-K23118252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09317
GSE171177,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100327_PCx_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.79738
PXDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24954
BRD-K93752373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.59926
BRD-K74676765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08611
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETV4_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6868
TAGLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14875
MAPK1IP1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12641
GSE175787_13_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K81619018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12183
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K85398599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08186
3050_FDPS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.629896
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51596
GSE220520_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142588_2_v_3_cinobufagin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K49005954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17656
BRD-K84362145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37176
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	4.69318
GSE225762_1_v_0_pcmt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAEA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14883
MCF7_Fulvestrant_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00851839
SLC5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72648
GSE200673,GSE200691_2_v_3_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158182_5_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC17A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04293
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A00881124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26254
GSE150895,GSE150896_0_v_1_kif15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE94849_1_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K93613839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8813
GSE235066_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K60936953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13061
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE125782_3_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE183271_1_v_0_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K66413698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46231
GSE228430_2_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K48670593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03975
GSE154577_6_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FKBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11317
BRD-K45628030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10744
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K10343715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01045
GSE190947_1_v_0_xbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7589
GSE154577_6_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE249098_3_v_2_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K86268010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07677
CHMP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30854
GSE184902_4_v_1_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE99875_2_v_0_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K37219127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56443
GSE190681_1_v_0_rtcb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE159473_0_v_1_eif5a2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K83190598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01607
BRD-K80877725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60704
CRCGN016_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.54599
BRD-K79735667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17005
MCF7_Azacitidine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150382
BRD-K24382357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99514
GSE199255,GSE199356_3_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE187006_3_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K01142063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22057
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NDUFS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08441
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213588_9_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE159678_6_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE228181_3_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05135
GSE162739_8_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210476_2_v_1_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nobox	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.7632
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178227_1_v_0_tet1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K37975989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75823
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE201309_5_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_3_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6855629-pone.0225186.s009.xlsx-Sheet1-DEGs_downregulated_in_HEK293_MEIS1_KO_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEx SalivaryGland 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-4.302
Nrf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.5124
GSE158834_1_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K08679933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39077
BRD-K13559806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5653
GSE84148,GSE96938_3_v_1_nrros_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
APOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.909
BRD-K30220159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12796
CRCGN015_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.22057
GSE247862,GSE247863_4_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	252.326
BRD-K82064887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75841
GSE138938_1_v_4_foxp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110178_1_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE155031_5_v_2_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.625
CRCGN015_MCF10A.TP53.M_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1559
BRD-K58075863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00304
GSE201309_1_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
9689_UVRAG_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.61899
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.0056
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K91043938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03317
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.7609
MED10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10593
BRD-K56381552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39316
BRD-K44007425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60461
BRD-K93624320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00843
GSE167956_4_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193993_4_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K99530482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83306
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Chimp_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
EPPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52773
GSE173997_1_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3642
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	1.0	2.23809
BRD-K43051162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52237
GSE155031_5_v_1_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.9028
GSE154577_7_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PAQR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03813
GSE235682_3_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.4674
BRD-K71615409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05022
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-Unnamed_0_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K60430111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22997
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5145
BRD-K58644442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0162
PMC8481886-Table_2.xlsx-A_subsets-common_MSC_AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213588_10_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139455_7_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K03608799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22177
GSE142210_2_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K79318959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14295
MCF7_Toremifene Citrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0122287
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K02374169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11026
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152432_1_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K46124507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13421
positive regulation of intracellular signal transduction	GO Biological Process Annotations 2025	1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5773
NMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40165
BRD-K45811188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18675
Cells - EBV-transformed lymphocytes	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.893738
GSE70499_0_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203308_7_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K60547079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20203
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228430_1_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K36198653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08761
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
10123_ZIC5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.740653
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A16313205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08629
BRD-K45062933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18148
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
5869_NUDT21_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.515648
BRD-K20026212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57085
PMC7518873-abb0205_Table_S1.xls-TFEB_targets-ensembl_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K47271260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03697
496100315_TCx_no dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.79651
GSE155567_3_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.79281
PMC8384902-mmc5.xlsx-H128_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K25573760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36456
GSE116810_2_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K16251850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31647
GSE252857_1_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196259_1_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129370_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K76960970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11884
GSE70499_3_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A45349889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.36697
GSE185881,GSE185884_2_v_3_ctcf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K16496140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28552
GSE158834_11_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ANKRD13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19878
GSE102505_4_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205163,GSE205164_1_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PARP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11643
CENPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.233
BRD-K70843862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10528
GSE164483_2_v_0_venetoclax_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K92195351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10096
BRD-K81982648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06627
GSE147366_1_v_2_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K87082948	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83304
H2BC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0855
BRD-K85234739	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56765
GSE154464_1_v_3_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.9058
BRD-K21678546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02773
4657_CARMIL1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.581816
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.1306
GSE158834_2_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K96076719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04463
GSE205021_3_v_2_fenofibrate_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211177,GSE211178_9_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE231720,GSE231724_2_v_1_setd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MGAT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44344
BRD-K42697646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34917
GSE154577_13_v_5_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233548_3_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.717821
GSE158834_1_v_6_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Ki16425_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139786
GSE96991,GSE97117_4_v_2_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_3_SED-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K73523821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03638
BRD-K60631127	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79225
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	1913.56
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K85161353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14109
BRD-K53335788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20165
GSE111247_11_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28513
GSE154464_1_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TIMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54604
BRD-A07861932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09548
BRD-K91588908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23491
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K64055457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08114
GSE96649_1_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE115363_3_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K82877426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51992
GSE233183,GSE233187_2_v_6_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE156923_2_v_1_rbmx_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9734180-41398_2022_2274_MOESM8_ESM.xlsx-Supplemental_Table_2-Supplemental_Table_2_Genes_regulated_by_TFEB_expression_are_altered_in_MAPT_p_R406W_brains_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN016_MCF10A.TP53.M_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24257
BRD-K22797212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62202
PMC11143964-jciinsight-9-161356-s009.pdf-13-SMAD5_SMAD5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K64424704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.46225
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K42785890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28851
STAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08804
BRD-K34405227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14362
GSE158834_2_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE209533_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
EEF1AKMT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03765
GSE231799_2_v_1_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE71674,GSE71676_0_v_2_cbfa2t2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K32727528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.24092
BRD-K10211218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0143
TBX18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9079
BRD-K22071228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15591
EXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.101
GSE228181_2_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K16689648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02658
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S3.xlsx-Day_4_GATA6-dependent_genes-GATA6-dependent_mRNA_expression_Day_4_Definitive_Endoderm_FDR_0_05_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE178340_7_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K85162983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4251
BRD-K81463178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08795
BRD-K21595913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03414
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K13567350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05817
BRD-A54347351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28949
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K46739745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1122
GSE158182_4_v_7_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE115363_1_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K21622447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01447
BRD-K40206099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08936
GSE210101,GSE210114_7_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK4_unique_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151612_0_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE114284_4_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184902_4_v_1_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169205_4_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K20809650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35554
MYC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15763
GSE211128_9_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K92981306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8253
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.594556
BRD-K86981519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21548
GSE152666,GSE152668_2_v_1_carm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128099,GSE128159_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K02866760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30526
GSE142210_2_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A87494167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02886
GSE96649_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K55169051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13623
GSE89767_2_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.8998
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111247_0_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K12879624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00588
GSE70499_3_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Mesna_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144779
BRD-K85659077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24448
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	298.406
PATZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63297
BRD-K37656403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3766
BRD-K75410936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03939
GSE248858_4_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158834_1_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE242083,GSE242098_3_v_0_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K31377965	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11185
BRD-K77697841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16151
BRD-K61124142	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02348
GSE158834_1_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7423359-abb8771_Table_S4.xlsx-Sheet1-Genes_detected_at_least_twice_in_h4E_BP1-hyperTRIBE_711_genes_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE176008_8_v_3_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199204,GSE211619_4_v_2_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169152_5_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K10545066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65756
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158632_3_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195568_2_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0534
9886_XAB2_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.69325
GSE248858_4_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE70499_4_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE136232,GSE136234_0_v_1_zpbp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S8-DUX4_SpecDMCs-Unnamed_3_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
9909_XRCC6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.573329
BRD-K38713368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23054
EDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22093
BRD-K58614056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18666
BRD-K07781811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31281
BRD-K15285842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23266
BRD-K57365604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68685
BRD-K78323315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57258
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	188.214
BRD-K73442516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78359
GSE199543,GSE239447_0_v_6_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148263_6_v_0_trim3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_10_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213588_8_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE114284_1_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CREG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06409
GTEx Breast 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-3.24646
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K70565285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04257
BRD-K62325456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44608
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.6487
GSE168076,GSE168080_1_v_0_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76672145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06623
GSE239541_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TDGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03275
GSE233183,GSE233187_3_v_6_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.0231
GSE158834_11_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE155031_6_v_2_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K47748211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2989
BRD-K50046044	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22477
BRD-K11990377	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00621
GSE188721_3_v_4_mesp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K72773830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01731
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_RG108_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146591
CRCGN012_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50676
PMC8384902-mmc5.xlsx-H2107_PROX1_ChIP-Symbol_PROX1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE110708_0_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K13488816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18466
GSE152055_0_v_1_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K79072801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30006
GSE201877_1_v_0_yap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
8405_SRFBP1_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.48799
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Chimp_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149901_3_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148252_0_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE123943_4_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-M34385771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42088
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:B17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2052
BRD-K71808107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05347
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K50985475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9544
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K19702946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67745
GSE149075_6_v_5_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213588_8_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
1165_CAMKK2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.625108
BRD-K81322049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.91666
GSE247862,GSE247863_2_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE179974_3_v_1_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ETV5::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.6647
BRD-K26127374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0685
BRD-K61248288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13261
BRD-K30795375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42476
PMC12254391-41598_2025_8960_MOESM5_ESM.xlsx-Suppl_Table_6_DEG-Supplemental_Table_6_Differentially_Expressed_Genes_DEG_between_siRNA_DLX4_and_siRNA_control_n_3_RA_FLS_cell_lines_per_treatment_group_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K00048792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0796
CRCGN009_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.8454
GSE184892_4_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE163297_0_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MINK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48911
GSE261563_3_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5437
CRCGN015_MCF10A.WT.HP_24H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26444
ARRDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23146
BRD-K13859368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07018
BRD-K95443593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20789
MCF7_Mercaptopurine_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.011828
BRD-K55171585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03234
CRCGN015_HEPG2_48H:O23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04396
CRCGN016_MCF10A.WT.HP_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.50266
CRCGN015_MCF10A.TP53.M_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.4977
CRCGN008_HEPG2_24H:G16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3418
GSE48812_2_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SCOC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37266
BRD-K95455263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60782
GSE229309,GSE229314_4_v_1_elavl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K76539747	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65896
BRD-K60454848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07473
INTS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49395
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4732
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	108.583
GSE166169_1_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K62370517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.48581
496100574_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.64879
GSE203267_0_v_1_alkbh5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4784
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22065
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE241108_1_v_0_sulfasalazine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_11_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171311_0_v_1_ellagic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE136869_1_v_0_lpar2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K25608271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74104
GSE159049_1_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K77173942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07081
BRD-K90231936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64169
GSE70499_5_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.77616
BRD-K19645475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51817
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE110708_2_v_3_adar_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4515549-NIHMS63168-supplement-3.xlsx-1B_HNF4A-reg_genes_post-treat-GeneSymbol_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE140651,GSE140653_2_v_6_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A43575461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28275
GSE202310_1_v_0_ube3d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE114284_1_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K48899005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00311
BRD-K84794783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01413
BRD-A48913311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08882
SLC52A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37611
BRD-K05392698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64335
GSE101467_0_v_1_dock8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K88836117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60721
BRD-K44799944	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57488
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K34228325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81062
4950_MED27_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.552665
GSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16638
BRD-K00231307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21857
GSE169152_3_v_7_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K75130046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03111
GSE237040_6_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE210101,GSE210114_2_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226285_3_v_0_nr0b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A64774838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66585
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.757412
CRCGN015_MCF10A.TP53.M_24H:P21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15715
1774_COPG1_P1	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	4.33045
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K48676303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10132
BRD-K54732353	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12396
CRCGN015_MCF10A.TP53.M_24H:F08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0799
NAP1L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14064
GSE202587_1_v_0_xrn1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4519778-srep12524-s2.xls-Table_S5-Supplementary_Table_S5_List_of_all_identifed_alternative_transcription_events_betweeb_MDMs_and_IPSDMs_and_in_LPS_response_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PROSER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07245
GSE245270_2_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100550_TCx_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27171
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K88388723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36769
GSE203308_4_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
6555_POLR3A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.884683
TTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65258
BRD-K33456231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72014
BRD-K51342021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34901
BRD-K99564685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69393
GSE114258_3_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A89354030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45668
MBOAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05633
GSE246184,GSE246195_0_v_1_sin3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26285
BRD-K23868551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1964
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K58930048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23726
SETDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35279
GSE211128_4_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SPIN2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0337
PRPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47821
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229468,GSE229471_0_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Zbtb2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1452
GSE77108_6_v_2_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	943.681
BRD-K85622666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08251
GSE158834_11_v_5_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.4799
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K67556876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00454
GSE48812_9_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A19962819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22026
BRD-K54881917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41477
BRD-K97595801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69628
GSE140092_0_v_1_socs3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K97707303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29085
BRD-K88369626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31091
GTEx Nerve 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-13.5337
BRD-K75065750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24819
BRD-K79877849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43211
CRCGN008_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0619
GSE228413_2_v_5_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234340_1_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25142
BRD-K52924481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.19643
BRD-K17718789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76447
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE89018_6_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178340_5_v_6_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_12_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
8598_SUPT5H_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.653661
GSE70499_4_v_6_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126463_1_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K77490065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10018
BRD-K20278539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07275
GSE158182_3_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE80098,GSE80366_0_v_6_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-542-DMTF1_DMTF1	Rummagene Transcription Factor Associations 2026	1.0	null
UBTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11024
BRD-K12749985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06829
GSE178340_5_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.7205
BRD-K55414200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19173
GSE228106_0_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.81093
GSE164529_0_v_2_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K11757577	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07762
1578_CHML_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.732905
CDV3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26003
BRD-K06784595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14996
PMC6347838-13046_2019_1042_MOESM3_ESM.xls-PRDM16_group_peak_anno-Gene_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_10_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K83898323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03443
BRD-K79184750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78716
UBXN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85522
GSE181003_3_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K57242481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17879
GSE158834_12_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_11_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169152_5_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K49584388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34144
GSE140936,GSE140938_2_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K15157905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23342
CRCGN009_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.22218
ZNF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13191
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.12584
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.0521
MT-ND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20897
Diisocyanate-induced asthma	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
PFDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03715
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EVA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40221
GSE94849_1_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.81653
GSE164463_0_v_1_pax6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IZUMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23057
BRD-K70643771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40034
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184892_7_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_1_TRC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K38358574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.11619
CRCGN015_HEPG2_48H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.282
GSE92965_0_v_1_klf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Type I spiral ganglion neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
B4GALT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18223
THAP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06647
GSE199543,GSE239447_0_v_4_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K74216068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14658
BRD-K32259584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68218
GSE70499_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K97805186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26037
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2034
GSE222758_0_v_4_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE152441,GSE152442_0_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K52139780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37074
CARM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01252
BRD-K94049419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16344
GSE158834_10_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K15174326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08705
BRD-A14424697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26265
BRD-A07870296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33744
BRD-K02274100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22367
GSE210101,GSE210114_0_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE161302,GSE161304_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K15123815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05246
GSE160001,GSE160670_3_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A65806553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07478
GSE154577_6_v_5_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148066,GSE157787_9_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN011_HEPG2_24H:J13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.32925
GSE114284_4_v_5_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.29586
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K47577519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41586
GTEx Breast 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-4.32616
BRD-K08658757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25872
GSE148263_6_v_9_trim3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
G57321FI	GlyGen Glycosylated Proteins	1.0	null
GSE186440,GSE186443_3_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3290552-pone.0032232.s006.xls-MUC4-KD_vs_Mock-Unnamed_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE184892_4_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K31870622	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55344
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.6255
BRD-K44177822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50744
ERGIC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77213
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE186440,GSE186443_4_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K12710356	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2878
BRD-K75360899	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44392
GSE112761,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K06116445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73093
BRD-K15591233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37683
PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K79352289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00306
GSE158834_0_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K73795883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09639
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Nerve - Tibial	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.689657
BRD-K83108629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01496
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.749
GSE158834_1_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DUSP22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79056
BRD-K90059152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84429
PMC4909989-ncomms11840-s2.xlsx-down-regulate-TEAD4-S_YAP_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K79658624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19107
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31921
BRD-K88418404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66844
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	158.334
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE116810_2_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBX20	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2062
SPRING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79308
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K39342915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58681
Ovary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.645576
CSNK2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48937
GSE140936,GSE140938_0_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7039
UGGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46781
BRD-K14070721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05866
BRD-K13486159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11514
BRD-K93316985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.47752
GSE108326_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11684804-jci-135-174981-s193.xlsx-DESeq2_pseudobulk_AA_Ag_vs_Pre-Gene_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K97763545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57194
GSE139016_3_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE213588_10_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE151083_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216413_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE232836_2_v_6_morphine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MTFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17494
CRCGN017_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4757
BRD-K97638135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.25395
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE168233_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K92767663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75087
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10082046-41467_2023_37049_MOESM6_ESM.xlsx-Sheet1-Supplementary_Data_3_Genes_downregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
ENO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29027
BRD-K05471809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28883
GSE254649_3_v_1_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
1422_CDK11B_ENST00000317673.7,ENST00000340677.5,ENST00000407249.3	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.512328
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-geneName_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6189
GSE124014_0_v_1_nnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184902_4_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE218879_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K16525290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04522
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.8967
GSE81796_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K53257131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14646
mecamylamine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54441
BRD-A73590800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18494
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K39863565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07248
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_2_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1699
GSE218060_5_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRKCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14344
BRD-K88099511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14791
BRD-K86946907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28627
GSE158834_1_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K21409337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00826
EOMES	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0166
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_12_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM41A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63671
GSE198794_0_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06701
H2AC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2388
BRD-K86746660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25415
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	161.118
BRD-K73095160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23041
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0856
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	285.918
BRD-K31348453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1951
BRD-K86025005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23426
BRD-K60839995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05157
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K39813155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47009
BRD-K87418665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.282
PMC12769604-13402_2025_1147_MOESM6_ESM.xlsx-Table_S4_3_Venn-Tumor_AND_Prognosis_NOT_Scissor_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE110178_2_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4202
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.3444
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202284,GSE202289_12_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE77108_0_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.037
GSE104604_1_v_0_eif5a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE118490_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K94385157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23588
BRD-K64001802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06658
GSE158182_5_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE206226_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11960529-mmc4.xlsx-Ventricular_ZNF711_KOoverCT-gene_ZNF711	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K97798118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29083
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.32595
BRD-K92974694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01026
BRD-K96288607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41915
GSE111247_14_v_10_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K47036878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02554
CPSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74909
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.54667
GSE169152_5_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K86855109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25514
176_AFG3L2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.513735
GSE202434,GSE202438_4_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lhx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.478
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-down-Gene_ID_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K71870778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35309
BRD-K83466873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28921
GSE211128_4_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
4959_MED9_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.66595
BRD-K92311828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41573
GSE168401_2_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
DACT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22478
BRD-K04819729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19262
GSE198165,GSE198166_9_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6853299-pbio.3000476.s011.xlsx-Fig_4A-RA_812_genes_expression_ratio_in_ZF_and_OF_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K38935430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0965
GSE184902_4_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K47804666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88064
GSE218727_2_v_1_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K91180296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32085
BRD-K09903493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11201
BRD-K17885598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48916
BRD-K91784140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00909
BRD-K28122619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58743
9949_YTHDF2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.555918
CRCGN017_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10675
GSE179031_0_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE155031_5_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE98831_1_v_0_brca1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.4758
GSE146982_3_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_10_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K19315592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7349
GSE194396,GSE194429_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A47137250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48594
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE220520_5_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NDRG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07771
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.8743
A1CF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03531
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K64222382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33793
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_AR-42_1µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0071621
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K63277230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40558
BRD-K31441930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37759
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	114.566
BRD-K60127720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70086
GSE149075_1_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217071_3_v_0_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233183,GSE233187_2_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154577_2_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:D05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03555
GSE249098_1_v_2_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K96280720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62683
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78473
BRD-K34069025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.86438
BRD-K28995832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18493
GSE169152_3_v_1_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE249544,GSE249637_9_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE134214_0_v_1_ell2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A55411938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68786
GSE154577_7_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110178_1_v_3_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K91810283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.45491
BRD-K98935620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07446
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K49584663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20455
BRD-K59667434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17291
GSE195503_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K05335635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1673
BRD-K35324337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13245
BRD-K32881384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62317
GSE193993_1_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K37262603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88362
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.353
ZNF580	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58166
GSE166920_6_v_3_adalimumab_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K10900122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04694
BRD-K12181036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09348
BRD-K30326216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75412
BRD-K67211407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06492
BRD-K36397874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28661
IFT57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82009
GSE233679_12_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_2_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K35879814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65396
BRD-K44344720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20027
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.8803
PMC5058748-oncotarget-07-31177-s002.xlsx-ZNF224_gene_peaks_promoter-Table_S3_Genes_that_contain_a_ZNF224_enriched_region_within_1_kb_of_the_transcription_ZNF224	Rummagene Transcription Factor Associations 2026	1.0	null
GSE171175,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE168171,GSE168173_0_v_1_ddx41_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Neurociticism	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.739794
BRD-K84118789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65807
PCMTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15755
GSE104508_0_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K76500652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4306
GSE213588_9_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMPD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47933
BRD-A19615705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46948
BRD-K54484733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28015
BRD-K57830670	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22088
GSE171179,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A06327019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.70024
GSE226544_1_v_0_hnrnpa2b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.2496
GSE191015_1_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4212
BRD-K92172862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90571
BRD-K92949288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16391
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-NEUN_UNIQUE_DYS_GENES-PAX6_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE235596_0_v_1_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K85475457	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.7529
BRD-A61522392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34252
GSE169356_0_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K60932633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11434
GSE220520_5_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PPIL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08324
GSE140937,GSE140938_0_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
H2AC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33292
GSE109530,GSE109531_2_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A52729710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57317
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	246.103
BRD-K79997957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98649
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K04366109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07225
6535_POLR1C_P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.506205
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE155031_6_v_1_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.5926
BRD-K45421483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56185
CRCGN015_MCF10A.TP53.M_24H:K17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11835
GSE203308_1_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71272
BRD-K62193937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24251
GSE229973_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK4_all_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN009_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26889
GSE216043_11_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATG2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24499
INO80E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15294
BRD-K09366011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.83235
GSE202434,GSE202438_6_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE198794_2_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K17061569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41706
GSE89018_1_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	120.399
GSE127916_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A54769817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96868
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE155305_2_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K32680124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26623
CRCGN008_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.7225
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K34117117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39893
GSE213588_9_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K47854067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4605
GSE186440,GSE186443_1_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17155
GSE89018_6_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K88498468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02615
BRD-K52473839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54646
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K17372597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17541
CRCGN014_HEPG2_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1672
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K14671808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04354
BRD-K21443215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50083
GSE189609_1_v_2_hax1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K80819226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83247
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0332
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	88.628
BRD-K83562499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08791
GSE158182_4_v_0_pnpla3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149075_6_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_42_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE154577_2_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K95651150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16502
5791_NR2E1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.628017
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K94833531	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.54077
BRD-K46162352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03485
GSE48812_0_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K88447092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4617
BRD-K24076516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09777
CRCGN015_MCF10A.TP53.M_24H:F22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.7719
GSE223540_2_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K53544328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48703
BRD-K85513337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.79624
GSE203017_0_v_1_irs2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223908,GSE223909_1_v_6_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K43324262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07542
VCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41895
BRD-K91094364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60625
4578_LIG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.543501
CRCGN009_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.85732
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RNPEPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42231
GSE158834_1_v_3_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139455_4_v_6_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228413_4_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12254391-41598_2025_8960_MOESM5_ESM.xlsx-fig-Supplemental_Table_6_Differentially_Expressed_Genes_DEG_between_siRNA_DLX4_and_siRNA_control_n_3_RA_FLS_cell_lines_per_treatment_group_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_8_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null