association	dataset	threshold value	standardized value
Cornified envelope formation	KEGG Pathways 2026	1.0	null
RFX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1402
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2609
GSE131903_0_v_2_abca12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE118077_1_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5279
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8759
CREM	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.143
RREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	146.818
SOX14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5613
Hair follicle bulge	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5063
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0651
AP1M2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4307
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.484
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.3404
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2636
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6165
POU2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7264
FOS::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1555
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4211
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7607
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1636
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.1251
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6585
ZNF677	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1145
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.5002
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
positive regulation of multicellular organismal process	GO Biological Process Annotations 2025	1.0	null
RBPJ	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4929
positive regulation of keratinocyte differentiation	GO Biological Process Annotations 2025	1.0	null
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9557
PMC11868582-41423_2025_1264_MOESM4_ESM.xlsx-Table_S10-Table_S10_List_of_FICZ-induced_or_FICZ-suppressed_and_OVOL1-dependent_genes_OVOL1	Rummagene Transcription Factor Associations 2026	1.0	null
Cornified envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.482
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7786
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0495
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.1785
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3508
CAPAN-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.047
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.8538
TCF21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.948
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	56.1737
chr1_152925447_C_T_b38	GTEx eQTL 2025	1.0	1.29047
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0598
AsPC-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5612
DCTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02584
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8228
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5565
Kco	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.98
ZNF76	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5444
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.6344
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9515
RFX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3767
me180	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.819
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4683
positive regulation of epidermal cell differentiation	GO Biological Process Annotations 2025	1.0	null
KLF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.1043
SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5861
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5654
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2774
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	78.9325
RFX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3856
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7499
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6292
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92201
GSE118077_1_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.5221
GSE184892_7_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.022
HOXC11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3145
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02534
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3984
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3332
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
Ventral disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.332
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2489
regulation of keratinocyte differentiation	GO Biological Process Annotations 2025	1.0	null
Epidermal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.143
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4968
GSE184892_6_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.0171
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6174
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ribonuclease H2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.93
GSE184892_6_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.663
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6681
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4292
Skin stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.25
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7566
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0441
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1452
Stratum corneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.231
PMC8881251-18_2022_4183_MOESM2_ESM.xlsx-ERM_vs_P1-DEGs_ERM_versus_P1_organoids_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.301
GSE118077_4_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE248634_1_v_0_gnas_human	RummaGEO Gene Perturbation Signatures	1.0	null
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3113
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.0332
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6827
Rad51C-XRCC3 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.733
RFX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7507
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2653
Corneocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.635
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1034
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3459
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2827
GSE118077_7_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
