association	dataset	threshold value	standardized value
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61214
MCF7_Triamcinolone Acetonide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161439
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54018
H3K79me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21203
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.346055
OTOL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94067
GTEX-QDT8-0526-SM-3NMD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14798
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.39326
GTEX-R53T-1826-SM-3GIJX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74949
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85862
MCF7_Sodium Phenylbutyrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130499
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8937
A549_MK-0752_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152715
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nerve	GTEx Tissue Gene Expression Profiles	1.0	1.34476
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.72248
DEOC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.41265
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906975
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.848623
GTEX-P44H-0226-SM-2XCEU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07652
GSE202134_0_v_1_rbm39_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.44291
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893051
PMC11585558-41467_2024_54547_MOESM8_ESM.xlsx-TP53_vs_WT_DEG_FFPE-gene_name_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06765
SUPM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78147
GTEX-WL46-0011-R9A-SM-3MJFP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875813
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03377
NCI-H226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.839556
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16373
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178340_7_v_6_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_BMS-265246_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130978
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FCH domain	InterPro Predicted Protein Domain Annotations	1.0	null
GSE161825_1_v_0_tipranavir_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QESD-1726-SM-2S1R7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46204
SF767	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46362
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908286
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65908
ZBTB33_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Striate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.11
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.13272
FCF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03469
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4931
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.95158
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.2924
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06727
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE71468,GSE76476_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MINO	CCLE Cell Line Gene CNV Profiles	-1.0	-2.59441
NR3C1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940283
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906279
MCF7_Nilotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0122797
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02396
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3651
GTEX-OHPM-1026-SM-3LK74	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832323
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.19628
Germ cell and embryonal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-W5X1-0826-SM-3GILN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1995
GSE233679_14_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.883592
MCF7_PD98059_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165694
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75464
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09153
GSE240386,GSE242143_1_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RNOR-0126-SM-2TF57	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00914
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.75602
GSE211151_1_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13725
regulation of cell migration	GO Biological Process Annotations 2025	1.0	null
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.479
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
U251MG	CCLE Cell Line Gene CNV Profiles	1.0	1.91
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0153
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_1_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S341-0626-SM-4AD5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965274
GSE210101,GSE210114_2_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SCC9	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37558
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75644
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06407
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.856
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EP300_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_6_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
Mesopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.852
GTEX-UJHI-0626-SM-3DB8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994052
3p deletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
GSE202434,GSE202438_6_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.21774
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06642
GSE178340_1_v_6_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Female pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.637
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NFK9-0226-SM-2HMKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952997
GTEX-RWS6-1126-SM-47JXC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866873
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42364
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.13541
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939335
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Subventricular zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.318
MBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02017
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24531
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.25969
ADAM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06833
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.832678
Medial cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.63
MCF7_Roxadustat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151163
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03624
UBTF	ENCODE Transcription Factor Targets	1.0	null
GSE182179_2_v_4_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
GSE150072,GSE169209_6_v_9_qser1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-1626-SM-2S1QW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1532
GSE195559_6_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11001
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WZTO-1026-SM-3NM9P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.933312
GSE169356_2_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RXRA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11001
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1792
Slit diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.846
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1224
PMC7617064-EMS151900-supplement-Extended_Data_Figure_7_Source_Data.xlsx-D23_NFIX-Logfold_change_threshold_1_0_1_NFIX	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904194
GTEX-PSDG-0226-SM-33HC1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25742
GTEX-RVPU-2226-SM-2XCAQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12074
GINS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17606
ZBTB33_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37606
GSE205630_0_v_1_gmds_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1409
MCF7_ENMD-2076 L-Tartaric acid_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0121389
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE213588_8_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894335
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34877
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86001
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_9_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BLVRB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18946
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11143
GTEX-XXEK-1726-SM-4BRVB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20323
GSE242083,GSE242098_3_v_1_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_TMP195_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0181035
GTEX-WH7G-0826-SM-4LVMR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03789
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2035
GTEX-X4EP-0726-SM-3P5YJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.411
GTEX-WY7C-2626-SM-3NB2P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17397
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35953
EP300	ENCODE Transcription Factor Targets	1.0	null
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52774
GTEX-OHPN-2926-SM-3LK65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17049
GSE126463_6_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Gestational trophoblastic neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.784
GSE213588_10_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89241
GSE193258,GSE193259_5_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE70935_3_v_5_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75842
A549_Valproic acid sodium salt_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129878
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17216
MRPL21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00384
GTEX-PW2O-1726-SM-2S1OO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04304
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07998
GSE147893,GSE147897_2_v_1_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Fourth ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.352
DLD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63825
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45461
IPO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14915
GSE116930,GSE116935_3_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22429
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.92518
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2314
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889543
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE188458_2_v_4_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152441,GSE152442_0_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GBX2-23144817-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997616
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.121
PMC12240782-Table3.xlsx-Sheet1-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE152441,GSE152442_7_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GTEX-R3RS-0526-SM-3GADG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21534
KMS21BM	CCLE Cell Line Gene CNV Profiles	1.0	1.34248
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889242
GSE119978,GSE180930_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08068
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Tozasertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014262
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33264
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF571	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21766
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927024
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34108
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27292
GTEX-NPJ7-1726-SM-2YUNA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913903
GTEX-QEG4-0526-SM-48TZD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871565
skin	GTEx Tissue Gene Expression Profiles	1.0	0.97842
GSE147283_1_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RM2N-1426-SM-2TF4H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984991
GTEX-S95S-1526-SM-2XCDH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908576
GTEX-RU72-1026-SM-46MUG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892937
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-POMQ-0326-SM-2I5FO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930642
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE178340_1_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RXRA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
1321-N1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.512
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92205
GTEX-NFK9-0426-SM-2YUNK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28225
GTEX-XQ3S-0626-SM-4BOOB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38804
TAF1	ENCODE Transcription Factor Targets	1.0	null
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193993_1_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWO3-1526-SM-48TCM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847083
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11663
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.874304
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE171837_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199538,GSE199539_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4479
GSE158834_11_v_6_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNB19	CCLE Cell Line Gene CNV Profiles	1.0	1.8646
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07453
CCNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08859
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164874_5_v_10_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
STON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16705
GSE210476_2_v_7_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ACSM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04703
GSE207301,GSE207303_1_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72343
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918852
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22822
GSE140651,GSE140653_2_v_7_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171837_0_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.20426
VPS36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63946
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PX3G-1026-SM-48TZW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07038
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933529
GSE231891_5_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199204,GSE211619_4_v_1_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U8XE-0526-SM-3DB8R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2726
MCF7_BRD4770_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159431
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1142
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27181
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21864
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936055
GSE102505_6_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1095
GSE125014_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23879
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.65679
GTEX-X3Y1-0726-SM-3P5YU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949853
496100566_FWM_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.84942
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883407
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEp3_UP_NR2F1_ind_UP-NR2F1_Ind_UP_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03044
GSE48812_9_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21362
GTEX-PLZ6-1426-SM-2S1OQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35917
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05234
ERVV-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59751
RNF26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35489
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAP2K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66425
GTEX-XAJ8-1126-SM-47JYA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907268
L363	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93449
BHLHE40_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.04383
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2043
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879012
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56835
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.94454
Filopodium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.234
Fetal Heart	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.07388
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	226.943
MCF7_Ofloxacin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138078
GTEX-QMRM-1226-SM-447C6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.985083
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1715
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.843606
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963697
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOSL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8598_SUPT5H_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.6289
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.982911
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1924
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16076
WM-266-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40689
BICD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25573
GTEX-OIZG-1126-SM-2HMIU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922081
GTEX-T6MO-0726-SM-4DM58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6624
A549_PD98059_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170019
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Gene_Name_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39713
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.6329
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89793
496100340_TCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64433
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-1126-SM-2TF6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19024
TARS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08782
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225382
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_CYC116_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134448
STAT3	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00314
K562_MC1568_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0199096
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.837547
GSE142210_2_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE167373_0_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98685
CAOV-4	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-1326-SM-2TF6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23169
GSE121198,GSE129779_3_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1409
GSE134029_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXP2_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226285_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06642
GTEX-WYVS-2426-SM-3NMA9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952651
GSE209698_0_v_1_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.951685
NCI-H1944	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.965624
glutamatergic synapse	GO Cellular Component Annotations 2025	1.0	null
MCF7_Tofacitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155268
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49404
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE142210_11_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WY7C-2126-SM-3NB2R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923205
GTEX-NPJ8-0426-SM-2HMK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848816
RBM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36586
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5184
MAZ	ENCODE Transcription Factor Targets	1.0	null
PMC9376070-41419_2022_5157_MOESM18_ESM.xlsx-Sheet1-Table_S4_Differentially_expressed_genes_of_HNRNPC-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL11A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-0826-SM-4DM76	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0312
FERMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08073
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_baboon_DRSG_lowerRes-Hg_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XBED-2526-SM-47JYD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975076
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.9805
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77701
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26642
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7	CCLE Cell Line Gene CNV Profiles	1.0	1.76077
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28756
GSE193258,GSE193259_5_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948399
BT20	CCLE Cell Line Gene CNV Profiles	1.0	1.38979
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13832
STAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57091
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01481
GSE206226_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29242
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.99347
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TML8-1826-SM-32QOR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55256
4945_MED22_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.13632
Autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
CBX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01325
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92898
GSE135030_3_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TKQ1-1426-SM-4GICK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88237
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89446
SK-MEL-24	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26739
GSE193258,GSE193259_2_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Congenital nervous system abnormality	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
Chromosome 15q13.3 microdeletion syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.587
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Hyperpallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.882
vitamin c_homo sapiens_gpl570_gse11919	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SW 527	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.994753
USF1	ENCODE Transcription Factor Targets	1.0	null
SIN3A_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193351_1_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0203
Clark-Baraitser syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IF-31-RN78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210037
GSE158834_11_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE193258,GSE193259_5_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12709797-12879_2025_11916_MOESM1_ESM.pdf-21-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.86087
ELK1::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8559
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95104
GSE178340_7_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28149
GSE119978,GSE180930_2_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31372
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20825
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54886
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.982911
GTEX-PWN1-1726-SM-2S1O9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09359
GSE206226_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE128333_2_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-1526-SM-3DB7I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83659
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12217
GSE242290_3_v_2_glutathione_human	RummaGEO Drug Perturbation Signatures	1.0	null
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	125.534
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.93512
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.84536
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	129.437
HS895T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49012
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17554
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168473_0_v_1_isoniazid_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSRNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21943
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Resveratrol_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145639
USH1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46749
GSE132694,GSE132717_0_v_2_meis1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S95S-0726-SM-4B64H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52666
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876871
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01123
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8755441-mmc3.xlsx-IRF3-Up-IRF3-Hela_IRF3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC11462941-CAS-115-2947-s001.pdf-50-ZNF558_ZNF558	Rummagene Transcription Factor Associations 2026	1.0	null
NAAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03868
GSE193258,GSE193259_9_v_0_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XGQ4-0226-SM-4GIDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838334
GSE160817_0_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_15_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Neocortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.817
GSE140646_0_v_1_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE242083,GSE242098_3_v_4_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193258,GSE193259_2_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_Ramelteon_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152918
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948033
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Tubastatin A HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129088
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76768
A549_Amisulpride_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162315
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96151
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45172
PMC10055234-media-3.xlsx-ZCCHC17_KD_DSGs_637-Unnamed_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.56897
SIX5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-19-JA87_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224656
ZBTB33_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03246
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.986128
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904933
Slit-Robo signaling complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.289
GTEX-W5WG-1726-SM-4LMI5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85323
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878039
GSE213650_3_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1619
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.35051
GSE125014_1_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29048
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02396
PMC12824906-mmc5.xlsx-Sheet1-Table_S4_Target_genes_of_FOXM1_and_their_expression_across_the_subtype_of_breast_tumors_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
CDC123	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75528
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative regulation of cell migration	GO Biological Process Annotations 2025	1.0	null
GTEX-U3ZN-2226-SM-3DB88	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47383
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.04531
regulation of cell junction assembly	GO Biological Process Annotations 2025	1.0	null
NCI-H1623	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99803
GTEX-WRHK-1426-SM-3MJF9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19071
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28753
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41733
NFYA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8866
A-375	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.909698
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5732
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_SB431542_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140216
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34977
UBQLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40729
GSE218378_1_v_0_pbx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_Triamcinolone Acetonide_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00884944
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.767
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-VUSG-2726-SM-4KKZJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22614
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879701
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61443
GSE211128_2_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128333_2_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of synapse assembly	GO Biological Process Annotations 2025	1.0	null
WM88	CCLE Cell Line Gene CNV Profiles	1.0	1.39825
496100323_FWM_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.14327
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Momelotinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178658
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SPI1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34977
Premature aging_Skin fibroblast_GSE10123	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.6366
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98466
PMC12230718-gkaf390_supplemental_file.pdf-10-NR2C2_NR2C2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24337
Filtration diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.845
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.087
QSER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02835
SP2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-0926-SM-4DM4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12768
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41477
ZNF263	ENCODE Transcription Factor Targets	1.0	null
ISG20L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0725
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Primary microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89431
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11001
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE166920_6_v_1_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.40428
GTEX-VJYA-1126-SM-3GIJU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906407
GSE211128_9_v_8_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977058
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8083
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	2.68317
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC5795782-supp_gad.302646.117_Supplemental_Table_S1.xlsx-Table_S1_2-Supplemental_Table_S1_2_Genes_significantly_upregulated_by_ARID5B_knockdown_ARID5B	Rummagene Transcription Factor Associations 2026	1.0	null
TCF12_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-1726-SM-3DB9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20551
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_1_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22178
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876465
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.81052
GTEX-RM2N-1726-SM-2TF55	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932202
GTEX-P4PQ-1026-SM-3NMCN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11797
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3299
ELF1	ENCODE Transcription Factor Targets	1.0	null
GSE134029_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22065
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE237984_1_v_0_magi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO 678	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23657
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20905
GTEX-R55D-1426-SM-48FEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00912
FHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17479
GTEX-PWN1-1626-SM-2S1OL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09229
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23385
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979437
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76184
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13756
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.858254
GSE140937,GSE140938_0_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XBED-0226-SM-47JY8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938894
GTEX-QV31-0626-SM-447C5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67191
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Table_S5C_Downregulated_genes_in_tumours_from_DCIS-SOX11_cells_compared_to_DCIS-lacZ_cells_injected_into_mammary_fat_pad_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNMC-1426-SM-2XCFM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935055
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32333
LS 174T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.35019
GTEX-T5JC-0426-SM-32PLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11633
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZXDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34383
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32791
BT-483	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.4721
GTEX-OXRK-0426-SM-3NB2E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887904
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88087
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	179.178
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92208
IRF4	ENCODE Transcription Factor Targets	1.0	null
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Unnamed_2_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MC116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21979
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE77108_8_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0237
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.822214
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE166184,GSE166185_1_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3651
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.384
KMS20	CCLE Cell Line Gene CNV Profiles	1.0	1.71162
GSE158632_3_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0126-SM-3GIK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839892
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.322661
GTEX-S341-1826-SM-3K2AB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.17674
GSE174498,GSE174500_3_v_4_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
Intine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.029
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72708
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.875767
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
RAB2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10734
MCF7_Enzastaurin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135696
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91718
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61723
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PLZ6-0726-SM-3P619	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888668
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	2.60898
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20639
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98704
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.833942
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU8-0526-SM-2XCDP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41768
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72195
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10234
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.82207
RETSAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25342
PMC11447041-41598_2024_74391_MOESM4_ESM.xlsx-B_ATF4-def_Tg_2_vs_DMSO_2-Supplementary_Table_4B_DEGs_in_ATF4-def_cells_comparing_Tg_2h_to_its_DMSO_control_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44306
GSE215461_0_v_1_topotecan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8469
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.954081
MOLP2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53361
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEP3_UP_AA_UP-AA_UP_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
OVTOKO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53943
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YMB1	CCLE Cell Line Gene CNV Profiles	1.0	1.9299
GTEX-RWSA-0726-SM-2XCBE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60487
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TML8-1326-SM-4DXTO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00721
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.9681
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31107
GSE231891_1_v_4_cdk8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE240439_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
STOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42456
1-alkyl-2-acetylglycerophosphocholine esterase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.6
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Subpallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28149
GSE205163,GSE205164_5_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
TCF4	MotifMap Predicted Transcription Factor Targets	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
estradiol_homo sapiens_gpl570_gse23610	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHRD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02039
GSE140965_1_v_4_mybpc3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28168
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP2	ENCODE Transcription Factor Targets	1.0	null
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.01026
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.953
JUND_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-1826-SM-3K2BH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19857
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00158
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
GLI3	MotifMap Predicted Transcription Factor Targets	1.0	null
WHAMM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01039
GSE193258,GSE193259_2_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_MK-5108_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172014
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07289
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.974803
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.3236
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.827477
GTEX-WRHU-0626-SM-3MJFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21035
GSE110580_1_v_0_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30631
GSE70935_3_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H4K20me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-0726-SM-4BOPU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90488
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00584
GSE111247_14_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.939219
MOLP8	CCLE Cell Line Gene CNV Profiles	1.0	1.4084
GSE199092_1_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE230744,GSE237803_0_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UJHI-1126-SM-4IHLN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31464
TCF3	ENCODE Transcription Factor Targets	1.0	null
MCF7_UNC0631_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136389
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201735_3_v_1_cdca7_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TT	CCLE Cell Line Gene CNV Profiles	1.0	1.66085
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13972
AASDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26053
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3986
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92294
valproic acid_homo sapiens_gpl570_gse14973	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE223908,GSE223909_4_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860461
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.81709
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834786
GSE151090_5_v_3_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.20182
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DOV13	CCLE Cell Line Gene CNV Profiles	1.0	2.20971
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.3803
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03335
GSE147876,GSE147877_2_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87783
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31077
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.35401
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYVS-1626-SM-3NM9R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919846
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825566
APAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0688
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899895
GSE210476_9_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04084
HCC95	CCLE Cell Line Gene CNV Profiles	-1.0	-2.07148
GSE240439_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56898
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.88087
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16249
PMC11811202-41598_2025_89390_MOESM1_ESM.pdf-2-SOX3_SOX3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11696420-41467_2024_55617_MOESM3_ESM.xlsx-Sheet1-Supplementary_Data_1_The_2495_differentially_expressed_genes_between_the_L3MBTL3_knockout_L3-KO4_or_L3-KO5_and_control_C_groups_of_SUM159PT_cells_L3MBTL3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Excitatory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.379
GSE178340_5_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.10523
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19897
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37086
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0335
MCF7_Linifanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136913
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.77279
H3K79me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.61899
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04878
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34348
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	155.423
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201309_4_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195663_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.49877
H3K79me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Azacitidine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177155
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3994
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.20307
GSE135350_3_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LMO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27222
GSE77108_8_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
Van der Woude syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27873
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10898
MCF7_Enzastaurin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144812
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE223908,GSE223909_1_v_3_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225869_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963291
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05553
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE148200_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10592471-NIHMS1912771-supplement-2.xlsx-NR2F1-Ind-Upregulated_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE120612_6_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QT-1426-SM-3NMCX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885353
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.905645
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE155567_1_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG8-2226-SM-3GIL9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07349
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10493
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TOV-112D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21203
GSE236437_2_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLIT-ROBO Rho GTPase-activating protein 2	InterPro Predicted Protein Domain Annotations	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16076
N4BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03365
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUYS-0326-SM-47JX2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16343
GTEX-SN8G-0126-SM-32PLI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40472
HT-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.92518
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60882
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.47772
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02169
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25125
GTEX-WHPG-2626-SM-3NMBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22022
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949831
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF510	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26239
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100564_TCx_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24055
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.68192
ZR751	CCLE Cell Line Gene CNV Profiles	1.0	1.43407
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146982_7_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ED-81-ZH14_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211113
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229468,GSE229471_0_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11185
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887136
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-SNOS-1526-SM-32PLW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874507
ZNF722	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16867
GSE254649_2_v_1_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20542
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31081
GTEX-QEL4-1326-SM-447AD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833027
MCF7_Meprednisone_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151265
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S95S-0826-SM-4B64N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998055
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19217
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.3817
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83723
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203485_1_v_0_sunitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.46889
TYK-NU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02268
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06399
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916554
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.246051
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21761
GSE155972_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE178340_7_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	66.9124
GTEX-OHPM-0126-SM-2YUN9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917607
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04785
GSE134029_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-VJYA-1726-SM-3NMDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890428
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	105.022
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_ZR75_KD-GeneID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935577
GTEX-V1D1-2426-SM-3GAER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15091
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28149
BATF	ENCODE Transcription Factor Targets	1.0	null
MRPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25838
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-0126-SM-48TDM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28036
HS600T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69345
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_S3I-201_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0119731
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF287	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12125
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE210476_9_v_7_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RXRA	ENCODE Transcription Factor Targets	1.0	null
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.994753
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21203
GSE152699,GSE152723_3_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.06698
H4K20me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-0426-SM-48U13	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919885
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41605
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE211128_3_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931079
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946387
GSE193993_4_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Nearest_Ensembl_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA1_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QLQW-1426-SM-2S1QU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31912
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9468
FTH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01208
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.864915
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16927
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAMA1	CCLE Cell Line Gene CNV Profiles	1.0	1.39724
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4EO-0126-SM-3P5YN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03221
GSE205163,GSE205164_3_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993986
GTEX-S33H-2326-SM-2XCB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16676
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874965
Primary autosomal recessive microcephaly 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
GTEX-XUYS-0126-SM-47JWZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04471
GSE178292_0_v_3_melphalan_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Ruxolitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140582
GTEX-OHPN-0011-R9A-SM-4DXUH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01796
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_11_v_3_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PSMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03151
GSE233679_6_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03674
PRELID3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54493
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF4_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHPG-2226-SM-3NMBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34684
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0993
GTEX-T2YK-0326-SM-4DM7D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966884
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.33833
GTEX-S7SF-2126-SM-3K2B2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06531
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6873
GTEX-N7MT-0726-SM-3TW8S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02816
GSE173307,GSE173391_0_v_1_rgcc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146982_7_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE246335_4_v_5_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AH-1626-SM-3GAF8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883686
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE197630_1_v_0_ruvbl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PABIR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23573
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.87892
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889833
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70444
GSE219195_4_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
METTL25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03185
PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20288
GSE128333_4_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.830925
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86185
GSE226249_2_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153258_1_v_0_dcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08674
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SUCS-1426-SM-4DM5W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974298
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.2119
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95143
GTEX-TML8-1626-SM-32QOO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05492
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88737
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.414
JK1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
GABPA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X8HC-1626-SM-46MWE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983298
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21203
EBF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01595
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850584
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.88203
GSE169356_2_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE103122_0_v_1_riok3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FB-32-PY27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208213
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BCL11A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47203
Dendritic spine head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.679
CBX3	ENCODE Transcription Factor Targets	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8020666-pnas.2015855118.sd09.xlsx-LPS_4_baboon_DRSG_lowerRes-Ensemble_gene_id_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TTLL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30149
GTEX-T5JW-1126-SM-4DM5V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.898179
GTEX-U3ZH-2026-SM-3DB78	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873816
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
creb1_18801183_k562_lof_human_gpl570_gds3487	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.196912
negative regulation of cell motility	GO Biological Process Annotations 2025	1.0	null
H3K4ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR3C1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0454
BCL11A	ENCODE Transcription Factor Targets	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.872071
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE135350_3_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Scimitar syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
GTEX-XBED-1926-SM-47JYP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954146
GSE239844_4_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RH30	CCLE Cell Line Gene CNV Profiles	1.0	1.77372
GSE239844_11_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CA-68-KG29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.244794
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850824
Pronephric tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.694
NCIH2122	CCLE Cell Line Gene CNV Profiles	1.0	2.85086
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZN-2126-SM-4DXU1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03644
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.85085
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.18802
GSE103068_0_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RTLS-0326-SM-2TF6A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975575
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1514
PMC6538380-elife-42374-supp3.xlsx-human-sp-ENSG00000007866_TEAD3	Rummagene Transcription Factor Associations 2026	1.0	null
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Regorafenib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141917
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02219
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Inhibitory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.421
GTEX-Q2AG-0126-SM-33HBV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83412
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35818
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880733
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-Aza_atRA_DE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.875237
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26438
GSE142210_3_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30442
HINFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8423
GTEX-Q2AG-0626-SM-2S1PV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13016
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0203
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21119
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14133
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08208
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVJ-1926-SM-2S1PJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.829655
GTEX-XMD1-0011-R9A-SM-4AT49	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50165
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13466
GSE239844_6_v_12_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
GSE116492,GSE116495_3_v_2_stag2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02445
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856133
GTEX-SSA3-0526-SM-32QPL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05602
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X4EO-0326-SM-3P5YO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889092
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE134029_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.35765
GSE239844_6_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE240386,GSE242143_8_v_4_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.902167
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.202612
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-0826-SM-48TZO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31713
Ventricular zone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.459
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.328
GSE206516,GSE206518_6_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8T8-0426-SM-3DB8X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30999
GSE225869_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30675
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.95759
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53699
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27783
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73143
GSE122509,GSE122513_2_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SH3BP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27712
GTEX-UPIC-0726-SM-3GADW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30614
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971305
GSE206516,GSE206518_0_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1162	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.26279
Auditory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.995
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19968
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20264
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80736
WSU-FSCCL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22178
GSE114883_0_v_4_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Lenalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0122611
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.977279
PMC12211354-12915_2025_2224_MOESM6_ESM.xlsx-Sheet1-Sheet1_The_source_list_of_zebrafish_Npas4b_targets_from_human_NPAS4_targets_in_CHEA3_database_NPAS4	Rummagene Transcription Factor Associations 2026	1.0	null
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.28848
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.125
FOXP2	ENCODE Transcription Factor Targets	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.946387
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07926
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35431
GSE231891_1_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AD-51-FB60_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225807
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10111
POLR1E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31844
hydrocortisone_homo sapiens_keloid scar_gds3071	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914705
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-1626-SM-2S1NH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.66475
ARHGEF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47528
GSE182680,GSE182683_0_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51284
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10864
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69111
GTEX-WYVS-2326-SM-3NMAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.7383
HAP-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.569
KMS26	CCLE Cell Line Gene CNV Profiles	1.0	1.49384
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908286
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43512
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.85945
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE184892_4_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73986
LN-229	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05046
143B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30285
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63508
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09367
GSE210101,GSE210114_5_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.379
n18	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.836
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936356
GSE190384,GSE190386_0_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2935
GTEX-SUCS-1626-SM-32PLS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895697
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWCY-0926-SM-48TD7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1988
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IM95	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3746
ZBTB33_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12697342-jem_20250471_tables3.xlsx-ileal_M-ILF_6_MRC-Gene_FOXK2	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBED-2226-SM-47JYQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983436
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-86-YY62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220786
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hallucinogen dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.217
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.96892
MET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07477
MICOS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36206
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869016
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.55143
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE140936,GSE140938_2_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GBX2	ChEA Transcription Factor Targets	1.0	null
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51333
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.6873
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22991
GTEX-UPK5-0326-SM-3GAF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.26631
GSE80537_5_v_2_adhfe1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE185744,GSE185747_0_v_4_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150055_0_v_1_melphalan_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUW1-1726-SM-4BOOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.980158
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41348
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925937
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_S3I-201_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0207896
MCF7_ITSA-1_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153177
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0661
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TMMY-0226-SM-33HBA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971089
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.72484
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pollen wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.518
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991666
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97462
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10534007-Table_2.xlsx-S5_unique_up_MSC_B-721_elements_included_exclusively_in_BFTC905_MSC_up_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899401
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CEP290	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06107
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87779
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41398
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.839556
GSE187006_3_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.03382
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KATO III	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04857
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.79496
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80035
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284265
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE203362_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14377
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21203
EN	CCLE Cell Line Gene CNV Profiles	1.0	1.53219
GSE108500_1_v_0_foxp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
MED12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19007
Dendritic filopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.549
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.887004
MCF7_Filgotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136347
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863721
MCF7_Mercaptopurine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138874
brain	GTEx Tissue Gene Expression Profiles	1.0	1.18096
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS 180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19841
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0226-SM-3NB2G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.866783
MDA-MB-435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51658
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2532
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.82674
regulation of synapse assembly	SynGO Synaptic Gene Annotations	1.0	null
TCF7L2_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Epididymosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.646
GTEX-VJYA-0826-SM-4KL1M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860382
PMC10742386-pnas.2311372120.sd05.xlsx-DLX3_EVT-Gene_Symbol_DLX3	Rummagene Transcription Factor Associations 2026	1.0	null
SK-N-BE(2)C cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.013
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.336
GSE111247_0_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE122509,GSE122513_3_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885856
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66389
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DNTTIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91946
GSE164874_5_v_6_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFON-1426-SM-4LVMT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26085
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932022
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21203
PMC9338531-13046_2022_2445_MOESM18_ESM.xlsx-AASE_ZR75_KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884337
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881876
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.33275
YY1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23127
GTEX-XUW1-0626-SM-4BOP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2178
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.3694
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_29_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SW 480	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3651
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913024
PMC8872993-41380_2021_1274_MOESM4_ESM.xlsx-Table_S6-Supplementary_Table_S6_Differentially-Expressed_Genes_after_T-3_KD_in_hiPSC-derived_Astrocytes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51442
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853987
MCF7_Tie2 kinase inhibitor_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0127323
GSE178340_7_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA2	ENCODE Transcription Factor Targets	1.0	null
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUW1-0926-SM-4BONX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917418
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE240386,GSE242143_8_v_6_morc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_8_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FF-90-JK74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.207388
DERL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19376
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
IRF4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NFK9-0626-SM-2HMIV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.25777
SIN3A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
regulation of synapse organization	GO Biological Process Annotations 2025	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3651
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.8828
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T5JW-0926-SM-4DM5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.23489
MCF7_Ruxolitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0132053
GTEX-RWS6-0926-SM-47JXE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00711
SIX5	ENCODE Transcription Factor Targets	1.0	null
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.86253
SKLMS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58591
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10791
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	3.27726
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2017
GSE166920_6_v_8_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993205
GTEX-WK11-2526-SM-3NM9Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03066
GTEX-XUJ4-2026-SM-4BOOW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890946
GSE242290_1_v_7_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB8OS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27454
PMC12663032-mmc7.xlsx-Supp_T6-Supplemental_Table_6_Dual_treated_vs_vehicle_treated_MSC_top_DEGs_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.898682
MCF7_Azacitidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163303
PMC11426526-ppat.1012555.s011.xlsx-Shared_DEG-Shared_DEG_between_MDDC_C91-PL_and_MDDC_Jurkat_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885836
GSE164874_5_v_11_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TRIM32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23718
EIF5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75557
GSE203181_0_v_1_phosphoramidon_human	RummaGEO Drug Perturbation Signatures	1.0	null
CL14	CCLE Cell Line Gene CNV Profiles	1.0	2.32392
SIKE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04513
GSE216757_4_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE115395_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
KHM1B	CCLE Cell Line Gene CNV Profiles	1.0	2.12162
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cul5-RING ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.606
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.22483
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Baboon_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE48812_2_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NTERA-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
GTEX-Q734-2026-SM-3GADA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49469
GSE188570,GSE188571_3_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-2526-SM-4E3HY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996708
ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8358
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18283
GSE230744,GSE237803_5_v_3_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Neuron spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.691
ZNF140	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5321
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.961598
Robust nucleus of arcopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.945
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69197
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BICR18	CCLE Cell Line Gene CNV Profiles	1.0	1.35265
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE146982_4_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
EMX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84723
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5184
GTEX-WL46-0626-SM-3LK7R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47139
MCF7_KW-2449_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0104188
PMC11615365-41467_2024_54246_MOESM6_ESM.xlsx-KK47-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
PMC11024925-mmc3.xlsx-Gene_lists-MV411_FOS_ChIP_and_RNA_overlap_after_10_nM_Gilteritinib_FOS	Rummagene Transcription Factor Associations 2026	1.0	null
SPI1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992457
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.859147
GTEX-P4QR-0726-SM-2I5GO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946445
GSE153443_1_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913021
GSE243879_1_v_0_elapor1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_4_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30942
GTEX-XPT6-2126-SM-4B66P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13815
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-0011-R9a-SM-2TC5R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938557
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21619
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836924
GTEX-NPJ8-0011-R9a-SM-2YUN5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930864
CAL-12T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08403
GTEX-WRHU-2826-SM-3MJG8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864575
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SCLC21H	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56674
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.909744
NPPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18995
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848043
GTEX-T5JC-0011-R9A-SM-32PLV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46087
K562_Lenalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0158671
PMC5637904-PATH-243-193-s016.xlsx-human_down_in_fat_SOX11-Unnamed_6_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83635
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.863239
496100666_HIP_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.18215
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.56
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01206
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06356
FAM234A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22555
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45701
ZBTB33_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.54324
GSE223908,GSE223909_1_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE203485_1_v_0_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO704	CCLE Cell Line Gene CNV Profiles	-1.0	-2.01379
GTEX-QCQG-2026-SM-2S1PH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36257
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14949
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_0_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
MCF7_Divalproex Sodium_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015011
SF126	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79352
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	1.0	5.5236
GSE218060_7_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	3.15514
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-1226-SM-2S1Q9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984302
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.79896
GSE186440,GSE186443_1_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE174701_5_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885498
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11045
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53945
High vocal center	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.511
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78567
rituximab_homo sapiens_gpl570_gds3829	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	111.842
GTEX-XUZC-1326-SM-4BRV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04877
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE144500_8_v_2_ventx_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Triamcinolone Acetonide_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.013347
PMC8481886-Table_1.xlsx-A_subsets-UC_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Entacapone_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.021043
NR3C1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.867731
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912895
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.825566
GSE201309_4_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKNAS	CCLE Cell Line Gene CNV Profiles	-1.0	-2.23425
GSE158834_11_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99976
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.265
FUZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14123
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
H2BC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2711
GTEX-PLZ5-1726-SM-2I5F6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.93194
GTEX-SNOS-1226-SM-4DM5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12519
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17487
GTEX-QLQ7-1826-SM-2S1R5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827818
GSE193402_0_v_3_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
Bladder	GTEx Tissue Gene Expression Profiles 2023	1.0	3.97821
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13547
MCF7_BMS-754807_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0137066
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PSDG-0626-SM-2S1OE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980175
MCF7_Glesatinib(MGCD265)_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159602
GSE206516,GSE206518_5_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE178340_7_v_4_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Arcopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.769
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.21362
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE210476_9_v_8_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U3ZN-2326-SM-3DB7W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938142
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03016
GSE201270,GSE201272_5_v_1_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE169205_4_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB33_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86001
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.61829
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Dendritic spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.692
PBX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993787
Glutamatergic synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPVG-2626-SM-4B669	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14598
PLEKHG4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44124
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2909
PMC11185762-media-2.xlsx-ATAC2wk_KD_V337M_intersect_peak-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.87892
HCC1897	CCLE Cell Line Gene CNV Profiles	1.0	1.51313
ERBB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28078
GSE246660_1_v_0_glycerol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE160817_0_v_8_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1703
REST_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.97193
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JIMT-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63436
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Microcephaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.292
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35417
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15496
GSE233049_2_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49708
CCRF-SB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00212
GSE114013,GSE114014_1_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pyramidal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.519
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.45592
GSE105173,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE166920_6_v_3_adalimumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOSL2	ENCODE Transcription Factor Targets	1.0	null
CTNNBIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15149
PHF8	ENCODE Transcription Factor Targets	1.0	null
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.32596
GSE155162,GSE155169_1_v_2_buparlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3651
GSE195559_8_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X261-0126-SM-3NMD6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38342
GSE152441,GSE152442_1_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.1427
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01618
MKN7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43104
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE121198,GSE129782_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27258
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.875767
KE97	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3905
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0336
496100385_TCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.04015
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91629
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11001
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.842695
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29349
GSE193258,GSE193259_5_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178340_5_v_4_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69129
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.6225
PRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70127
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15619
GSE202825_2_v_1_ano1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_PJ34_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0106502
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.10374
GSE247084,GSE247087_0_v_1_cdyl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH508	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43548
GSE209601_0_v_1_mef2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31146
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2	ENCODE Transcription Factor Targets	1.0	null
GSE217452_3_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86304
Trophoblastic neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.743
MYC_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
GSE164874_5_v_4_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997386
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07318
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
GTEX-PX3G-1526-SM-48U11	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26938
GTEX-R55F-1426-SM-2TF53	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836548
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4062
MYO1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53244
FOXA1	ENCODE Transcription Factor Targets	1.0	null
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE261563_6_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63246
GTEX-XLM4-1026-SM-4AT51	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876823
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE125219,GSE125221_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CAOV4	CCLE Cell Line Gene CNV Profiles	1.0	2.65422
FBH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06909
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.465
KDM5B	ENCODE Transcription Factor Targets	1.0	null
Cannabis dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.218
A549_PFI-1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163005
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50429
SPI1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WFG8-0326-SM-4LVN4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.045
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.1739
STX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01878
GSE169356_0_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207611,GSE207612_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE201270,GSE201272_5_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289749
JPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01028
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17312
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826926
GSE239844_4_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7824
Neuroepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52804
MCF7_Tacedinaline_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00992109
GSE249098_3_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45147
cetuximab_homo sapiens_gpl570_gse21483	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TKQ2-0426-SM-4DXUO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14447
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.35336
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00735
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.57867
GSE240468_3_v_6_nfyc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HES6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15063
GTEX-N7MT-0126-SM-2D7VT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24971
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.485
TTPAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59476
Pseudopodium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.184
496100664_HIP_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4093
STK38L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01609
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	1.0	1.44541
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171175,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH69	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37314
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F3_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
GTEX-XV7Q-2126-SM-4BRVX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69337
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.136
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30104
GSE155567_3_v_0_cd33_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-VJWN-0426-SM-3GIJI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13335
GTEX-OXRP-2526-SM-2S1NO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926725
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00445
TEAD4	ENCODE Transcription Factor Targets	1.0	null
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WDR55	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13991
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2082
GSE213588_10_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893985
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03818
GSE178340_1_v_2_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_0_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02631
MYBL2	ENCODE Transcription Factor Targets	1.0	null
GSE120612_7_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNU503	CCLE Cell Line Gene CNV Profiles	-1.0	-2.29732
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-AA_up_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
SP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.6478
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844782
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861309
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Dendritic shaft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.972
POLR2A	ENCODE Transcription Factor Targets	1.0	null
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.85759
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02396
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.90591
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52638
PMC9404532-NIHMS1788564-supplement-Supplementary_Tables_1-8.xlsx-Supp_Table_6-MYC_UP_V1_DN_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85034
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05527
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135030_11_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_8_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_13_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52567
GSE158438_5_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.871979
PMC4212256-mmc5.xlsx-FLI1_log2_results-MIR622_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_PHA-680632_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157842
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.27662
OAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16857
GTEX-P4PQ-1626-SM-2HMKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942893
SK-MEL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.834819
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.994753
SF1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.984835
Hippocampal pyramidal layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.519
HCC1187	COSMIC Cell Line Gene CNV Profiles	1.0	2.93899
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00882
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.62804
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28335
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28149
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15203
7SK snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.507
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946359
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.987554
GTEX-QCQG-2126-SM-2S1P8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22202
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE193258,GSE193259_2_v_8_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
gata3_21892208_mda_mb_231_gof_human_gpl570_gds4080	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.308503
GTEX-T2IS-2626-SM-32QPP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85543
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16249
Electric organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
TMEM186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03415
496100542_PCx_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.50655
GSE152441,GSE152442_6_v_2_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE165548_2_v_13_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RWS6-2026-SM-2XCB5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04798
OXER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01418
MCF7_Enzastaurin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134225
GTEX-S32W-2526-SM-2XCB8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14578
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HEPG2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.836
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.5063
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04857
A549_Anacardic Acid_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135742
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13827
GTEX-O5YV-0326-SM-2I5H2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05275
SIG-M5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16313
MCF7_Valproic acid sodium salt_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137581
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	2.95403
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23551
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLC7A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10538
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59789
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24999
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE217452_3_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PFDN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47771
GTEX-RWS6-2426-SM-2XCB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2228
H2AC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50996
GTEX-X3Y1-2426-SM-3P5Z7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829878
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14232
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null