association	dataset	threshold value	standardized value
stratum basale	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.521223
cell communication	GO Biological Process Annotations 2015	1.0	null
ZBTB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73625
Chordoid meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.161
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
medial pallium (hippocampal allocortex)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16256
BRD-K66619295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05532
trimipramine-4083	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN009_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.87946
SUZ12-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Puberty, Precocious	HuGE Navigator Gene-Phenotype Associations	1.0	null
abnormal respiration	MPO Gene-Phenotype Associations	1.0	null
hippocampal pyramidal layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.432225
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RC-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletal muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.192125
CRCGN017_MCF10A.TP53.M_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.70138
CRCGN014_HEPG2_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08928
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.019
LXF-289	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K12340493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14571
pancreatic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.563637
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.7354
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9735
PMC2694838-1471-2164-10-241-S2.xls-Sheet1-Regulated_genes_by_ZNF191_knockdown_ZNF24	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K59765110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27584
PTPN9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74973
Prostate adenocarcinoma_PRAD_TCGA-EJ-7791-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cho cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.183113
percentage	GeneRIF Biological Term Annotations	1.0	null
Gastric antrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.867
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7399-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
response to glucocorticoid	GO Biological Process Annotations 2023	1.0	null
PRB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17076
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5689-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.37813
NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
forebrain development	GO Biological Process Annotations 2015	1.0	null
ARL6IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13377
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861968
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8154
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EJM	DepMap CRISPR Gene Dependency	1.0	13.7824
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.0181
BRD-K08504955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11799
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.885597
genistein-5595	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
infundibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.223906
CRCGN015_HEPG2_48H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.09405
than	GeneRIF Biological Term Annotations	1.0	null
Nephrogenic Diabetes Insipidus	DisGeNET Gene-Disease Associations	1.0	null
SRIF-14	DGIdb Drug Targets 2026	1.0	0.302469
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.882701
Sarcoma_SARC_TCGA-FX-A3TO-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01676126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18016
Breast Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.829438
timolol-5280	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
female reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.511778
rifampicin-4008	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lyf-1	MotifMap Predicted Transcription Factor Targets	1.0	null
cellular response to corticosteroid stimulus	GO Biological Process Annotations 2023	1.0	null
cefsulodin-4067	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TGW	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
regulation of signaling	GO Biological Process Annotations 2015	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.309613
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCIH2066	CCLE Cell Line Gene CNV Profiles	1.0	1.37208
BRD-K82877426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87858
CRCGN015_MCF10A.TP53.M_24H:O22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.10105
propoxycaine-3583	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
increased interleukin-1 beta secretion	MPO Gene-Phenotype Associations	1.0	null
Taenia tecta, dorsal part, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18253
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
TRIM28	ENCODE Transcription Factor Targets	1.0	null
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6X2-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Field CA1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18711
fatty acid derivative metabolic process	GO Biological Process Annotations 2015	1.0	null
Obesity	HuGE Navigator Gene-Phenotype Associations	1.0	null
Complex laminated body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.825
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QC-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65731
Osteoporosis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K08154407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08656
Small intestine benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
Anchored component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.803
G-402	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ChIP_SUZ12_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12448
mucosal mast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.334865
Rectum adenocarcinoma_READ_TCGA-DC-6160-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Peptide ligand-binding receptors	Reactome Pathways 2024	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11597
HCC1954	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99377
cellular response to glucocorticoid stimulus	GO Biological Process Annotations 2025	1.0	null
PU.1-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN011_HEPG2_24H:I24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4196
fludrocortisone-282	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Piperonyl Butoxide	CTD Gene-Chemical Interactions	1.0	null
Flushing	DisGeNET Gene-Phenotype Associations	1.0	null
Squamous Cell Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
increased inflammatory response	MPO Gene-Phenotype Associations	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r7 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00373
bladder	GeneRIF Biological Term Annotations	1.0	null
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	115.071
HSG	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.867222
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6146-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLAG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	102.389
cancer	GAD High Level Gene-Disease Associations	1.0	0.300704
Pancreatic Ductal Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16018
Urinary Bladder Neoplasms	CTD Gene-Disease Associations	1.0	1.07553
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.987039
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10863010-media-2.xlsx-ST18-Unnamed_3_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
abnormal myeloid leukocyte morphology	MPO Gene-Phenotype Associations	1.0	null
9505BIK	DepMap CRISPR Gene Dependency	1.0	4.90594
SNU668	CCLE Cell Line Gene Expression Profiles	1.0	1.75467
BRD-K45817496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18123
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX17-20123909-XEN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cos-7 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.563637
Lower respiratory tract disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.176
BRD-K32423836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0621
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K09878843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16955
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hippocampal formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03358
Cortical amygdaloid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.054
G protein-coupled receptor dimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.11
Hypomagnesemia	DisGeNET Gene-Phenotype Associations	1.0	null
CRCGN013_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.21293
those	GeneRIF Biological Term Annotations	1.0	null
BRD-K98601267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01735
pituitary gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.113243
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN009_HEPG2_24H:M19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3849
APTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87012
Mesothelioma_MESO_TCGA-MQ-A4LP-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
Distal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.946
Memory Impairment	DisGeNET Gene-Phenotype Associations	1.0	null
SLR24	CCLE Cell Line Gene Expression Profiles	1.0	1.69623
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.27755
CRCGN015_MCF10A.TP53.M_24H:O23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3206
cyclase	GeneRIF Biological Term Annotations	1.0	null
Pontine central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38523
olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.265381
Follicular adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.35
CRCGN015_MCF10A_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.19176
abnormal tumor necrosis factor secretion	MPO Gene-Phenotype Associations	1.0	null
endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.875738
neuroendocrine carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.211597
PCSK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31487
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.994
levothyroxine sodium-4150	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45547
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma	DisGeNET Gene-Disease Associations	1.0	null
layer 6 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36855
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.523
Gigantocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21368
SLC4A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05895
SIRT3_KO_GDS4058_16_mouse_BROWN ADIPOSE TISSUE	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
cho-k1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.996295
Brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.123
NCI-H727 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.023
inferior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06785
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Connective tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
cortical amygdaloid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.76157
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.4437
BRD-K28912195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40444
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
SLC26A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65616
Entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.092
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.486326
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.865327
BRD-K30963311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07196
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10966
bone marrow	HPA Tissue Protein Expression Profiles	1.0	1.74715
Prostate adenocarcinoma_PRAD_TCGA-EJ-7792-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55183
Mesothelioma_MESO_TCGA-LK-A4NZ-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.062036
Posterior amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.105
NET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93778
Prostate adenocarcinoma_PRAD_TCGA-J9-A52E-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100619_HIP_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30265
Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Intestinal disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.253
Subiculum, dorsal part, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.2124
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16606
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.472704
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
layer 6 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06994
Diabetes Mellitus	DisGeNET Gene-Disease Associations	1.0	null
rostral presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10341
Hormone signaling	KEGG Pathways 2026	1.0	null
BRD-K95788660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44339
colonic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063512
colistin-4796	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BIM 23627	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.5788
H-C[CYS-PHE-LAGL(NΒME,BENZOYL)-TRP-LYS-THR-PHE-CYS]-OH	DGIdb Drug Targets 2026	1.0	1.51234
primary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.319863
FXR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68729
BRD-K76588804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67114
Nephrolithiasis	DisGeNET Gene-Disease Associations	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
coupling	GeneRIF Biological Term Annotations	1.0	null
GPCR ligand binding	Reactome Pathways 2024	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5191-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.55285
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9762
BRD-K72278003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16089
CRCGN015_HEPG2_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.82211
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02928
Primary hyperaldosteronism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.807
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05543
Medullary thyroid carcinoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.688
Azurophil granule lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.721
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6790-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 3 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07598
BRD-K88527653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39781
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38826
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
DU-145	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NCIH2291	DepMap CRISPR Gene Dependency	1.0	2.48533
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.649
SALL4-18804426-XEN-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
INPPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6858
Tumor Cell Invasion	DisGeNET Gene-Phenotype Associations	1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6614
Des-AA<sup>5</sup>-[D-Trp<sup>8</sup>]SRIF	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
CDK16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62033
6-azathymine-3987	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
downstream	GeneRIF Biological Term Annotations	1.0	null
Mood Swings	DisGeNET Gene-Disease Associations	1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Supramammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30773
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF1A	Pathway Commons Protein-Protein Interactions	1.0	null
Renal Insufficiency	DisGeNET Gene-Disease Associations	1.0	null
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.353
Agnosia	DisGeNET Gene-Disease Associations	1.0	null
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894081
Benign Prostatic Hyperplasia	DisGeNET Gene-Disease Associations	1.0	null
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.428783
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Olfactory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.763
weak	GeneRIF Biological Term Annotations	1.0	null
cimetidine-4063	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PEX12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04284
RAB40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99315
KP-N-RT-BM-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K76518272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08109
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
subgranular zone of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26073
Thyroid cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.67
GRK6	Pathway Commons Protein-Protein Interactions	1.0	null
explained	GeneRIF Biological Term Annotations	1.0	null
neurohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.176678
H3K9me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861968
Anchored component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.108
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
stomach smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.323144
lipid metabolic process	GO Biological Process Annotations 2015	1.0	null
Abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04027
Field CA2, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74658
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G8-01B-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4870-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.700722
Lung adenocarcinoma_LUAD_TCGA-44-3396-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Spinal meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
GSE205163,GSE205164_1_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN009_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.28917
Dorsomedial nucleus of the hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47776
Thyroid Nodule	DisGeNET Gene-Disease Associations	1.0	null
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
GSE210885_2_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-2.18888
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
substance-related disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
Endotoxemia	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K96567801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53665
Ulcerative Colitis	DisGeNET Gene-Disease Associations	1.0	null
Hydrops Fetalis, Non-Immune	DisGeNET Gene-Disease Associations	1.0	null
TGFBRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75663
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.983816
Cholangiocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.166
MKN74	DepMap CRISPR Gene Dependency	1.0	2.75362
paromomycin-3017	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Abnormal Behavior	DisGeNET Gene-Phenotype Associations	1.0	null
CRCGN014_HEPG2_3H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.84342
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.732265
serotonin-activated cation-selective channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.987
abnormal blood cell morphology/development	MPO Gene-Phenotype Associations	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955717
CRCGN015_MCF10A_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.25875
EPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94088
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Adult liver stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.936
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13I-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.448
samples	GeneRIF Biological Term Annotations	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
thyroid carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.343106
graves	GeneRIF Biological Term Annotations	1.0	null
Signaling by GPCR	Reactome Pathways 2014	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JV-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TYK2_KD_GDS4754_158_human_JURKAT	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
neuroectodermal tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.6608
superior parietal lobule, left, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0498
posteroventral (inferior) parietal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.928266
neuron projection	GO Cellular Component Annotations 2025	1.0	null
att-20 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.602892
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07986
RARG-19884340-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Pain	DisGeNET Gene-Phenotype Associations	1.0	null
(-)-isoprenaline-3571	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intestinal schistosomiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.454093
CRCGN010_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7017
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.54831
AQP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18579
monorden-493	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K09521953	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53728
periventricular stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48659
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H-c[Cys-Phe-LAgl(N<sup>&beta;</sup>Me benzoyl)-Trp-Lys-Thr-Phe-Cys]-OH	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.99223
cos-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.259254
BRD-K59064238	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60081
CD19+_BCells(neg._sel.)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.39308
Pulmonary Cystic Fibrosis	DisGeNET Gene-Disease Associations	1.0	null
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3599
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	2.66257
Striate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
GSE205070_1_v_6_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SCA1_Knock-in_GDS1756_234_mouse_Forebrain tissue - 12 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.23995
HCT8	CCLE Cell Line Gene Expression Profiles	1.0	1.48658
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7060-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Growth hormone secreting pituitary adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.005
BRD-K43017905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50326
tacrolimus-169	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Childhood Medulloblastoma	DisGeNET Gene-Disease Associations	1.0	null
Hepatobiliary system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Arteriosclerosis	DisGeNET Gene-Disease Associations	1.0	null
YKG1	DepMap CRISPR Gene Dependency	1.0	3.84871
GSE114992,GSE114993_1_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
negative regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
layer 6a of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36795
GPCR ligand binding	Reactome Pathways 2014	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88P-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.992342
IRS1_KO_GDS1219_303_mouse_brown preadipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Endometrial Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K70052888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71367
BRD-K34524418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29951
CRCGN017_MCF10A.WT.HP_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15636
uterine sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.139266
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
Hyperglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
Paraventricular hypothalamic nucleus, descending division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09081
response to peptide hormone	GO Biological Process Annotations 2015	1.0	null
Retrosplenial area, ventral part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08721
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GO-06A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
icosanoid metabolic process	GO Biological Process Annotations 2015	1.0	null
therapeutic	GeneRIF Biological Term Annotations	1.0	null
respiratory system phenotype	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.3253
BRD-K71554049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.23273
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5466-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retrosplenial area, lateral agranular part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15455
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.32015
PANC 08.13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.96845
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01906
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4347-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QV-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K26232524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18821
ependymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.474646
BRD-K09414286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95642
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.70046
Graves Disease	DisGeNET Gene-Disease Associations	1.0	null
cell	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.719015
neuropeptide receptor activity	GO Molecular Function Annotations 2025	1.0	null
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5318
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861968
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42409
leiomyosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.149594
intestinal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095057
Non-Functioning Pituitary Gland Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.442795
carboplatin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54441
Field CA2, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67361
response to nitrogen compound	GO Biological Process Annotations 2015	1.0	null
CAKI1	BioGPS Cell Line Gene Expression Profiles	1.0	0.848554
Complex Partial Status Epilepticus	DisGeNET Gene-Disease Associations	1.0	null
PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
somatostatin receptor activity	GO Molecular Function Annotations 2023	1.0	null
CRCGN014_HEPG2_24H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.687
Adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.137
ophthalmopathy	GeneRIF Biological Term Annotations	1.0	null
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
MIER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23395
cellular response to organic substance	GO Biological Process Annotations 2015	1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
tissues	GeneRIF Biological Term Annotations	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.384
CORT	Pathway Commons Protein-Protein Interactions	1.0	null
Melanoma	DisGeNET Gene-Disease Associations	1.0	null
periventricular stratum of r4Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24689
BRD-K34405227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02744
cholecystolithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.695905
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146546,GSE146807_0_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053732
intermediate stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18101
GH4-C1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.454
JVE015	DepMap CRISPR Gene Dependency	1.0	2.16565
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65452
Brain Lower Grade Glioma_LGG_TCGA-DU-7292-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K16330310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.213
positive regulation of signaling	GO Biological Process Annotations 2015	1.0	null
sst5	GeneRIF Biological Term Annotations	1.0	null
Vitamin D-dependent rickets type 2B	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.18
RCHACV	DepMap CRISPR Gene Dependency	1.0	5.91348
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05195
NUGC4	CCLE Cell Line Gene Expression Profiles	1.0	1.90972
use	GeneRIF Biological Term Annotations	1.0	null
Steatohepatitis	DisGeNET Gene-Disease Associations	1.0	null
sulmazole-4009	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.868142
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.489838
ventral posterior inferior nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.825142
abnormal immune cell physiology	MPO Gene-Phenotype Associations	1.0	null
Glioma	DisGeNET Gene-Disease Associations	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HES6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4169
gh1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.166
BRD-K45537529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33657
Adenohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.731
Myenteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.927
ZR-75-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10297
Stomach disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUIT-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33696
Cholinergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.657
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.925631
Kidney renal papillary cell carcinoma_KIRP_TCGA-EV-5901-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3313-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anthracosilicosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MH-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CORTISTATIN-14	DGIdb Drug Targets 2026	1.0	0.252057
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.799728
abnormal leukocyte morphology	MPO Gene-Phenotype Associations	1.0	null
HS616T	CCLE Cell Line Gene Expression Profiles	-1.0	-3.60144
Retrosplenial area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14601
SNU216	CCLE Cell Line Gene CNV Profiles	1.0	1.56483
Kidney renal papillary cell carcinoma_KIRP_TCGA-PJ-A5Z8-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SMAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7312
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.830709
CRCGN015_HEPG2_48H:F16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.3297
sulfasalazine-204	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059176
etiocholanolone-6060	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7391
outer SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.38897
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.221989
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.123
Lung Diseases	CTD Gene-Disease Associations	1.0	1.1862
BRD-K53706972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92174
functioning pituitary adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.708364
BRD-K31577322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12867
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.482038
BRD-K05251963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19834
CRCGN010_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.11435
Hormone Refractory Prostate Cancer	DisGeNET Gene-Disease Associations	1.0	null
BRD-K55402144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06877
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
MARK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19005
ING5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.94687
azathioprine-5627	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.913041
neuropeptide receptor activity	GO Molecular Function Annotations 2015	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4890-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.056896
BRD-K28559679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38228
Hyperpituitarism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.482
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.9063
BRD-K08702524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17541
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
KYSE270	DepMap CRISPR Gene Dependency	1.0	2.72192
sublayer 6b of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29745
biperiden-5644	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
edema	MPO Gene-Phenotype Associations	1.0	null
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.399
BRD-A69950438	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3555
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Ovarian Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
Retrosplenial area, lateral agranular part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23039
NALM16	DepMap CRISPR Gene Dependency	1.0	6.12943
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11D-11A-12R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased grip strength	IMPC Knockout Mouse Phenotypes	1.0	null
HS683	DepMap CRISPR Gene Dependency	1.0	2.01546
Thyroid gland carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.709
CRCGN016_MCF10A.TP53.M_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.9039
BRD-K68949590	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1295
BRD-K75745696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0766
abnormal immune serum protein physiology	MPO Gene-Phenotype Associations	1.0	null
mantle zone of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50906
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05543
BRD-K11008696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09956
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35518
Asthma, allergic_Bronchial epithelium_GSE3004	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.24508
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041079
A-Netherlands-602-2009(H1N1)_0Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.92902
BIM 23454	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8618
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Leukemia, Acute Megakaryocytic_Megakaryocyte_GSE2433	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.20906
Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.46289
temporal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.880185
Orbital area, ventrolateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02084
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.868432
JARID2	ChEA Transcription Factor Targets	1.0	null
erastin-6369	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.40064
BRD-K42976515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21531
MZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29906
KDM4A	ENCODE Transcription Factor Targets	1.0	null
showed	GeneRIF Biological Term Annotations	1.0	null
TT2609C02	CCLE Cell Line Gene Expression Profiles	-1.0	-2.774
Olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.786
CRCGN015_HEPG2_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	10.0
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.7962
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.79
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.7942
trihexyphenidyl-4015	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K07350528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24001
g-protein coupled receptor dimeric complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.819452
Primitive neuroectodermal tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.828
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4101-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Anterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06255
Perturb_14988_KO_Phf8_SRP093797	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.25154
abnormal cell-mediated immunity	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_HEPG2_48H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.87452
subcallosal cingulate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.23201
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.34664
BRD-K65464642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22032
Perireunensis nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32371
pancreatic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.55408
NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4934
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1645
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.865501
ZBTB22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84917
PMC10863010-media-2.xlsx-ST18-Unnamed_4_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
adenomas	GeneRIF Biological Term Annotations	1.0	null
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.34509
BRD-A77164655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46485
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GAREM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7601
RUNX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3038
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.21228
BRD-K98935620	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37069
Primary somatosensory area, upper limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14903
NCI-H1666	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86757
medial mammillary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.848231
Pancreatic adenocarcinoma_PAAD_TCGA-FB-A4P5-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.446038
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.282225
BRD-A89354030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14042
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5550-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CGP 23996	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Hypoglycemia	DisGeNET Gene-Disease Associations	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.984321
CTCF-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Tumor Initiation	DisGeNET Gene-Phenotype Associations	1.0	null
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.776673
sublayer 6a of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.145
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.955329
Multiple Sclerosis	DisGeNET Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867427
Angiomatous meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.261
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
CHLA90	DepMap CRISPR Gene Dependency	1.0	3.75829
CRCGN015_MCF10A_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2382
STRN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87622
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78361
negative regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
increased interferon-gamma secretion	MPO Gene-Phenotype Associations	1.0	null
PECAPJ41CLONED2	DepMap CRISPR Gene Dependency	1.0	3.64363
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZK-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
immune system phenotype	MPO Gene-Phenotype Associations	1.0	null
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.57879
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ABC-1	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.41265
Hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.704
GRANTA519	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61757
Infralimbic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.806
Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WSU-NHL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
female reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.584022
intermediate stratum of PHyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22625
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.632
negative regulation of cell proliferation	GO Biological Process Annotations 2015	1.0	null
Pancreatic Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Glomerular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
periventricular stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33112
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4874-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2444	COSMIC Cell Line Gene CNV Profiles	1.0	2.08712
L-803 087	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
BRD-K79318338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00251
CRCGN008_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8555
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3761
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.63526
response to endogenous stimulus	GO Biological Process Annotations 2015	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
Perturb_8587_KO_Adnp_SRP063269	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.16529
Bipolar disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K28030757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04727
Autism	DisGeNET Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.74146
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.307889
Pars intermedia	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
Cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.171
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.539
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.3619
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1504
response to hormone	GO Biological Process Annotations 2015	1.0	null
BRD-K16357911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17824
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10819
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.904957
r7 part of the basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02765
CIDEC_KO_GDS3776_552_mouse_Brown and white adipose tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06398
Necrosis	CTD Gene-Disease Associations	1.0	1.7568
TF1	DepMap CRISPR Gene Dependency	1.0	2.20664
heterogeneously	GeneRIF Biological Term Annotations	1.0	null
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.322779
BRD-A26343863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22982
AR	ChEA Transcription Factor Targets	1.0	null
compared	GeneRIF Biological Term Annotations	1.0	null
ChIP_PHC1_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CST-17	DGIdb Drug Targets 2026	1.0	0.302469
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.643669
Substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216
Parathyroid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.998
rostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04009
22RV1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormal leukocyte physiology	MPO Gene-Phenotype Associations	1.0	null
mantle zone of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04883
GTPase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.099
Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A654-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-7489-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K76617730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40799
RTL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12712
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
SCC-9	GDSC Cell Line Gene Expression Profiles	-1.0	-1.78429
15-delta prostaglandin J2-201	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypoglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.353
median eminence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.236627
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4813-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleus subcoeruleus, r1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15902
Gall bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.386
P300-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC7495487-41598_2020_71030_MOESM2_ESM.xlsx-Sheet1-NR1A1_THRA	Rummagene Transcription Factor Associations 2026	1.0	null
boldine-4004	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5712-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sublayer 6a of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06626
U20S	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.867222
BRD-A88691416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.984
hippocampus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	120.141
corticosterone-4064	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.4193
ZNF32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63099
CRCGN015_HEPG2_48H:O10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.14097
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Priapism	DisGeNET Gene-Disease Associations	1.0	null
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.50813
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.242054
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.247852
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13854
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5694-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
Obesity	DisGeNET Gene-Disease Associations	1.0	null
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.34334
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.901909
AGS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908763
496100582_HIP_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.88594
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.904161
NCIH1573	CCLE Cell Line Gene CNV Profiles	1.0	2.59983
BRD-K56699877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11784
regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
epiandrosterone-2444	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GR-ST	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Orbital area, lateral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16052
male reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.518465
ChIP_H3K9me3_19884255_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
response to glucocorticoid	GO Biological Process Annotations 2015	1.0	null
KYAE-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K64591035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27181
lung	GTEx Tissue Gene Expression Profiles	1.0	0.854536
E2F1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
retromammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01753
gastroenteropancreatic	GeneRIF Biological Term Annotations	1.0	null
moxonidine-4084	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
enzalutamide_homo sapiens_gpl570_gse44905	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Large cell neuroendocrine carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
lungs	GeneRIF Biological Term Annotations	1.0	null
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.751645
Perturb_15041_KO_Klf2/Klf4_SRP095733	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.34465
biological_process	GO Biological Process Annotations 2015	1.0	null
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.252919
periventricular stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30535
CD105+_Endothelial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.958507
peptide receptor activity	GO Molecular Function Annotations 2015	1.0	null
Perturb_9818_KD_GATA3_SRP103740	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.38348
GSE95688_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SmoothMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.929256
basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.558856
Field CA2, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10056
Primitive neuroectodermal tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
Taste Sweet	DisGeNET Gene-Phenotype Associations	1.0	null
ar4-2j cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.749166
Adult T-Cell Lymphoma/Leukemia	DisGeNET Gene-Disease Associations	1.0	null
RCH-ACV	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.76269
Adrenocortical carcinoma_ACC_TCGA-OR-A5JJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCA 420	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05543
WASL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22997
positive regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H69 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05543
octreotide	GeneRIF Biological Term Annotations	1.0	null
secretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.976315
BRD-K96549574	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49152
metronidazole-4023	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CSB-26484114-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RE-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN012_HEPG2_24H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66204
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058994
GSE139966_1_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SW1088	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56967
SNU216	DepMap CRISPR Gene Dependency	1.0	3.38406
tumors	GeneRIF Biological Term Annotations	1.0	null
JHOM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77275
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SQ-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19445
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955717
PRL-2915	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
Signaling by GPCR	Reactome Pathways 2024	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86039
PPARG	ChEA Transcription Factor Targets	1.0	null
ATP11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56851
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52083
59M	CCLE Cell Line Gene Expression Profiles	1.0	2.97318
sst3	GeneRIF Biological Term Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CJ-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nociceptive Pain	DisGeNET Gene-Phenotype Associations	1.0	null
cell periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.179459
NCI-H1648	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.74883
BRD-K57051157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08163
CRCGN015_HEPG2_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7335
Angiogenic Switch	DisGeNET Gene-Disease Associations	1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.945664
Inflammation	CTD Gene-Disease Associations	1.0	1.90192
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041136
methapyrilene-6644	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AHR-22903824-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC4050971__F3	PFOCR Pathway Figure Associations 2023	1.0	null
phenelzine-2357	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Primary somatosensory area, trunk, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05393
MSTO-211H	COSMIC Cell Line Gene Mutation Profiles	1.0	null
regulation of mapk cascade	GO Biological Process Annotations 2015	1.0	null
low	GeneRIF Biological Term Annotations	1.0	null
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.398356
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.22812
NCI-H1105	COSMIC Cell Line Gene Mutation Profiles	1.0	null
negative regulation of cyclic nucleotide metabolic process	GO Biological Process Annotations 2015	1.0	null
nordihydroguaiaretic acid-203	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-J2-8194-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19943
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
BRD4-27068464-CHIP-SEQ-AML-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
synaptic transmission	GO Biological Process Annotations 2015	1.0	null
SMAD4-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_HEPG2_48H:G05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.09453
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4009
Lung adenocarcinoma_LUAD_TCGA-49-6761-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bile duct epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.155
BRD-K43653210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25407
MN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97218
Heterotrimeric G-protein signaling pathway-Gi alpha and Gs alpha mediated pathway	PANTHER Pathways	1.0	null
Small intestine neuroendocrine neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.386
BRD-K52989901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91917
BRD-K66253165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02409
PRKDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54676
detected	GeneRIF Biological Term Annotations	1.0	null
TUR	COSMIC Cell Line Gene CNV Profiles	1.0	2.08712
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hypothyroidism	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.930103
EBF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7753
Tumor Progression	DisGeNET Gene-Phenotype Associations	1.0	null
olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.261284
flucytosine-6450	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cellular response to stimulus	GO Biological Process Annotations 2015	1.0	null
Blastoma	DisGeNET Gene-Disease Associations	1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864963
CRCGN015_HEPG2_48H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.92256
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.22094
CRCGN017_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91382
prolactinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.558674
cSARS Bat SRBD_12Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.79098
Huntington Disease	DisGeNET Gene-Disease Associations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MN-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.955693
signal transduction	GO Biological Process Annotations 2015	1.0	null
GSE92965_0_v_1_klf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Field CA1, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.44254
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Tripartite attachment complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.646
eticlopride-3393	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69278
male reproductive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.542566
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.265677
posterior (caudal) superior temporal cortex (area 22c)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22173
BRD-K66419338	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.162
HS888T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.46537
precuneus, left, inferior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.961776
cell motility	GO Biological Process Annotations 2015	1.0	null
OCT4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.982125
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BIM 23295	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15693
positive regulation of phosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
dentate gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.255234
evaluation	GeneRIF Biological Term Annotations	1.0	null
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063113
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.28559
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.986
Conventional (Clear Cell) Renal Cell Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Intracellular canaliculus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.687
BRD-K89278382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53781
Brain cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.903
GSE205163,GSE205164_3_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO800	CCLE Cell Line Gene Expression Profiles	-1.0	-1.87596
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16103
nialamide-4347	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20344
CRCGN014_HEPG2_3H:M21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.9908
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
Down Syndrome Critical Region	DisGeNET Gene-Disease Associations	1.0	null
CRCGN009_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.84895
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
ICC2	DepMap CRISPR Gene Dependency	1.0	9.92715
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.6182
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.598469
reproductive system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.676987
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.28367
MHHES1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.86603
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1966
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
negative regulation of camp metabolic process	GO Biological Process Annotations 2015	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1723
Gastrinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.963
Heterotrimeric G-protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.12
ACN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K87290989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24739
BRD-K66762690	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31642
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Differentiated Thyroid Gland Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.545
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13492
CRCGN010_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.46521
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6252
Uveal Melanoma	DisGeNET Gene-Disease Associations	1.0	null
CAPAN1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.45474
Polycystic Ovary Syndrome	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K13844473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15637
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFKB1	JASPAR Predicted Transcription Factor Targets	1.0	null
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36277
NCI-H727	COSMIC Cell Line Gene CNV Profiles	1.0	2.08712
CRCGN016_MCF10A.TP53.M_24H:D15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49965
SPI1-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TCF7L2_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
myoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.124329
CRCGN011_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5822
496100635_HIP_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03498
tanespimycin-381	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.748753
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0027
SW 982	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825571
Primary somatosensory area, lower limb, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05255
cobalt chloride-383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KU1919	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72693
denatonium benzoate-5061	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.172799
Perturb_9754_KO_Cfb_SRP333300	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.58619
GSE215109_0_v_2_ep400_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
neuropeptide binding	GO Molecular Function Annotations 2023	1.0	null
transmembrane signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
Hypotrichosis	DisGeNET Gene-Disease Associations	1.0	null
CRCGN015_MCF10A_48H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3036
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7590-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3312
GSE139966_4_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
[D-Tyr<sup>8</sup>]CYN 154806	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.29213
P53-22387025-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Congestive Heart Failure	DisGeNET Gene-Disease Associations	1.0	null
Lung disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.144
LTA4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0555
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.09738
endocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.262986
BRD-K49999779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24051
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0477
cytoplasm	GO Cellular Component Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
thioperamide-3392	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K63926219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16471
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIM28-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-92-7341-01A-31R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50613
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11373
Cpa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
BRD-K32916996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59029
U266B1	CCLE Cell Line Gene Expression Profiles	1.0	1.37258
CRCGN011_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.02985
RUNX2	ChEA Transcription Factor Targets	1.0	null
abnormal granulocyte morphology	MGI Mouse Phenotype Associations 2023	1.0	null
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.10122
Tetralogy Of Fallot	DisGeNET Gene-Disease Associations	1.0	null
CAL-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K12015168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81769
equilin-5620	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EFO-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cellular response to glucocorticoid stimulus	GO Biological Process Annotations 2015	1.0	null
BRD-K28510065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82369
GTPase activator complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.668
BRD-K68530167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15215
acth-secreting pituitary adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.447311
BRD-K97763545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09483
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
lymph	GeneRIF Biological Term Annotations	1.0	null
cellular response to chemical stimulus	GO Biological Process Annotations 2015	1.0	null
Irritable Bowel Syndrome	DisGeNET Gene-Disease Associations	1.0	null
mantle zone of CA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62622
23132/87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00623
CRCGN015_HEPG2_48H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.67313
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Sepsis	DisGeNET Gene-Disease Associations	1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.034
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.1863
meninx	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095679
YMB1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32318
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.069119
somatostatin receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.62357
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.458
DIP2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00667
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17321
Field CA1, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.51083
CRCGN014_HEPG2_24H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.30535
chloropyrazine-5750	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.094
troglitazone-504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Corticotroph adenoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.811
Polycystic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
MEC1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.38013
Medullary thyroid carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.913
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.1437
Cholelithiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.494
Cholestatic Pruritus	DisGeNET Gene-Phenotype Associations	1.0	null
CRCGN014_HEPG2_24H:D13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82099
BIM 23068	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
GSE145915_3_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K09337184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13642
Autoimmune disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
G protein-coupled GABA receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.799
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03235
AHR-22903824-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.2271
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9966
flumetasone-2551	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
blood vessel endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.236921
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.063561
roxithromycin-2992	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K70618663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99548
HCC2279	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47131
CRCGN011_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2756
ESR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68699
peduncular part of dorsomedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.12451
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03229
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39534
BRD-K80940089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14139
BRD-K69248736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2734
Compact myelin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.578
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.143
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7049-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
signaling receptor activity	GO Molecular Function Annotations 2015	1.0	null
GSE152432_5_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RCOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73592
yohimbine-2755	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Adenoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.753
PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nadolol-4021	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GPCR, rhodopsin-like, 7TM	InterPro Predicted Protein Domain Annotations	1.0	null
abnormal interleukin-1 beta secretion	MPO Gene-Phenotype Associations	1.0	null
Scleroderma_Fibroblast_GSE1724	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.53011
ADRBK1	Pathway Commons Protein-Protein Interactions	1.0	null
Tectum mesencephali	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.208
anterior lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.317315
unsaturated fatty acid metabolic process	GO Biological Process Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5ZE-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
BRD-K77403813	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02426
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.9731
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.805213
cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K77609086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30048
NCI-H661	COSMIC Cell Line Gene Mutation Profiles	1.0	null
embryoday10.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.02435
Lung adenocarcinoma_LUAD_TCGA-55-6972-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sublayer 6a of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18151
propantheline bromide-3013	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A89038047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05138
Septicemia	DisGeNET Gene-Disease Associations	1.0	null
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10275
regulation of cell communication	GO Biological Process Annotations 2015	1.0	null
CMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
SOX3-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ethambutol-4001	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kaposi Sarcoma	DisGeNET Gene-Disease Associations	1.0	null
PMC3923219-mmc2.xls-Table_S1-Table_S1_Differential_Gene_Expression_in_GFP-PRDM1_transduced_H9_hESCs_PRDM1	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4344-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.217352
treated	GeneRIF Biological Term Annotations	1.0	null
JARID2-20064375-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K85500722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18601
CRCGN015_HEPG2_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.77329
Complete Trisomy 21 Syndrome	DisGeNET Gene-Disease Associations	1.0	null
BRD-K22229373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32662
gametocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.133518
Anterior olfactory nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.82
BRD-K57786075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1267
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
malignant pleural mesothelioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.229024
BRD-K16560691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09662
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.16
Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abducens motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09816
GM1600	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.867222
BRD-K58996625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10982
Papillary Thyroid Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
positive regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
TSH producing pituitary tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.721
CRCGN015_HEPG2_48H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.98868
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.864092
CD71+_EarlyErythroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.50759
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A5ZZ-01A-31R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPI1-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5483-01A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUZ12-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hormone producing pituitary cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.647743
Precursor B-Cell Lymphoblastic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
Calu-3	GDSC Cell Line Gene Expression Profiles	-1.0	-1.42786
G protein-coupled receptor, rhodopsin-like	InterPro Predicted Protein Domain Annotations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4784-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuropeptide receptor activity	GO Molecular Function Annotations 2023	1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041091
Medulloblastoma	DisGeNET Gene-Disease Associations	1.0	null
LUDLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.63049
Prelimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01339
Carcinoma, Basal Cell	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane part	GO Cellular Component Annotations 2015	1.0	null
mantle zone of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18489
biliary tract cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.058543
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.906384
r5 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06894
BRD-K95365728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02569
Pancreas disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.674
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.4
mammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01424
gallbladder cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.164786
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38535
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
intermediate stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05058
Left Ventricular Hypertrophy	DisGeNET Gene-Disease Associations	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of signal transduction	GO Biological Process Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4225-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01639343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.58252
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18787
Anophthalmia And Pulmonary Hypoplasia	DisGeNET Gene-Disease Associations	1.0	null
equilin-3377	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K78323315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71872
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
germ cell and embryonal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.572273
SLC37A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34555
Pituitary gonadotropin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.373
NCIH358	CCLE Cell Line Gene CNV Profiles	1.0	1.38211
[D-TYR8]CYN 154806	DGIdb Drug Targets 2026	1.0	0.302469
BronchialEpithelialCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.33931
Erythroleukemia (Erythroid/Myeloid)	DisGeNET Gene-Disease Associations	1.0	null
PMC3251736__F2	PFOCR Pathway Figure Associations 2023	1.0	null
colonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063267
NCIH292	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81532
Liver hepatocellular carcinoma_LIHC_TCGA-K7-A5RG-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BIM 23454	DGIdb Drug Targets 2026	1.0	0.302469
Somatostatin receptor 4	InterPro Predicted Protein Domain Annotations	1.0	null
D-283MED cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
HS746T	CCLE Cell Line Gene CNV Profiles	-1.0	-1.588
Arthritis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K64536135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51019
Peptide GPCRs	WikiPathways Pathways 2024	1.0	null
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.318
BRD-K07770425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13425
hydralazine-3621	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K92725027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09793
Anxiety	DisGeNET Gene-Disease Associations	1.0	null
Anterior cingulate area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23624
mantle zone of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29813
pituitary adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.894179
HT1080	BioGPS Cell Line Gene Expression Profiles	1.0	0.848554
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.63007
Pituitary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.847
anterior olfactory nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.368998
[125I]TYR11-SRIF-14	DGIdb Drug Targets 2026	1.0	0.756171
dorsal thalamus_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.84848
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0022
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.579216
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.576015
regulation of phosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-3_E2F2-Gene_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
Thoracic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
specimens	GeneRIF Biological Term Annotations	1.0	null
CHO-K1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.784
monocarboxylic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.83686
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03894
pleural cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.226607
POU5F1	ChEA Transcription Factor Targets	1.0	null
uterine leiomyosarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.171923
trimethylcolchicinic acid-2802	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Hyperactive Behavior	DisGeNET Gene-Phenotype Associations	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9I7-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSS131R	DepMap CRISPR Gene Dependency	1.0	2.46091
BRD-K49733809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46077
cell migration	GO Biological Process Annotations 2015	1.0	null
fatty acid metabolic process	GO Biological Process Annotations 2015	1.0	null
layer 6b of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43015
CRCGN015_HEPG2_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.59326
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6324-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100489_HIP_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15381
CRCGN014_HEPG2_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.03952
H3K9me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Multiple endocrine neoplasia type 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
PMC6360815-supp_gr.239053.118_Supplemental_Table_S2.xlsx-MAFs_targets-Table_of_potential_MAF_targets_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
pheniramine-4012	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
valproic acid-348	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Seizures	CTD Gene-Disease Associations	1.0	1.07376
Primary Effusion Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
studies	GeneRIF Biological Term Annotations	1.0	null
glia	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219928
ovary	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
benzylpenicillin-6155	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-genes_with_only_SALL4_peaks-Protein-coding_genes_that_show_only_CUT_RUN_peaks_with_2_SALL4_antibodies_and_no_other_antibodies_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
Metabolic disorders of biological oxidation enzymes	Reactome Pathways 2014	1.0	null
intestinal cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061217
abnormal immune system physiology	MPO Gene-Phenotype Associations	1.0	null
BRD-K30198800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20298
Gastrointestinal neuroendocrine tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
haloperidol-5638	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H-c[Cys-Phe-LAgl(N<sup>&beta;</sup>Me benzoyl)-DTrp-Lys-Thr-Phe-Cys]-OH	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
SUZ12-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
RH18	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4586
Antral mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	117.864
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.8066
UQCR10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57224
[125I]CGP 23996	DGIdb Drug Targets 2026	1.0	0.302469
LU-134-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Malaria	DisGeNET Gene-Disease Associations	1.0	null
Neuroactive ligand-receptor interaction	KEGG Pathways 2026	1.0	null
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.069331
HCC1143	CCLE Cell Line Gene CNV Profiles	1.0	1.37764
H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Atypical Ductal Breast Hyperplasia	DisGeNET Gene-Disease Associations	1.0	null
abnormal cytokine secretion	MPO Gene-Phenotype Associations	1.0	null
Squamous Cell Carcinoma Of The Head And Neck	DisGeNET Gene-Disease Associations	1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09502
SNUC1	CCLE Cell Line Gene Expression Profiles	1.0	1.77519
fluocinonide-3933	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-AAUM-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5250-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27991961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13898
Orbital area, lateral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00046
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
increased acute inflammation	MPO Gene-Phenotype Associations	1.0	null
Cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.132
positivity	GeneRIF Biological Term Annotations	1.0	null
adrenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.304279
mantle zone of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36261
GSE164508_1_v_0_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217115_3_v_5_alectinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K56427898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44996
CRCGN016_MCF10A.TP53.M_24H:K05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.4562
abnormal bronchial provocation	MPO Gene-Phenotype Associations	1.0	null
posteromedial visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23891
increased airway responsiveness	MGI Mouse Phenotype Associations 2023	1.0	null
Pituitary gland tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.921
Lung adenocarcinoma_LUAD_TCGA-38-4627-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8513_KO_Setd1b_SRP328849	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Malignant Tumor Of Colon	DisGeNET Gene-Disease Associations	1.0	null
BRD-K05051664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10295
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.6247
Endothelial Dysfunction	DisGeNET Gene-Phenotype Associations	1.0	null
SOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74504
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.08
chlorhexidine-5403	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Status Epilepticus, Subclinical	DisGeNET Gene-Disease Associations	1.0	null
Obesity-related traits	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
pasireotide	CTD Gene-Chemical Interactions	1.0	null
Class A/1 (Rhodopsin-like receptors)	Reactome Pathways 2024	1.0	null
enterochromaffin-like cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.293
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.834363
TCF4	MotifMap Predicted Transcription Factor Targets	1.0	null
Type 2 diabetes mellitus_Renal Tissue_GSE642	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.30729
neuroactive ligand receptor interaction	KEGG Pathways	1.0	null
CRYGD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59063
GH3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.668
BRD-K86192746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52734
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4993-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11951866-mmc1.pdf-36-RREB1_RREB1	Rummagene Transcription Factor Associations 2026	1.0	null
sstr2	GeneRIF Biological Term Annotations	1.0	null
increased susceptibility to type IV hypersensitivity reaction	MGI Mouse Phenotype Associations 2023	1.0	null
COLO775	CCLE Cell Line Gene Expression Profiles	1.0	2.70969
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	1.03245
BRD-K67533212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82731
UGGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99951
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1-26456572-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
STAT3-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
dorsomedial tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09998
Somatostatin receptor family	InterPro Predicted Protein Domain Annotations	1.0	null
GSE112995,GSE132079_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
resveratrol-662	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Borderline Personality Disorder	DisGeNET Gene-Disease Associations	1.0	null
BRD-K61441533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.65252
Anterior cingulate area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29354
SKOV3	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.83915
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.900417
TMEM256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62057
Lung squamous cell carcinoma_LUSC_TCGA-37-4132-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3331
dorsal peduncular cortex, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18305
H3K9me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76206
POLR2A	ENCODE Transcription Factor Targets	1.0	null
EBF1-22473956-LYMPHODE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X8-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K29794647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.70369
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5402-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10694
GM97	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.23436
fosfosal-2997	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8419-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26297
promoter	GeneRIF Biological Term Annotations	1.0	null
uterine leiomyosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.160773
abnormal immune system cell morphology	MPO Gene-Phenotype Associations	1.0	null
abnormal sensory capabilities/reflexes/nociception	MPO Gene-Phenotype Associations	1.0	null
neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044028
PMC8755441-mmc3.xlsx-IRF7-Up-JARID2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
YMB-1-E	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10248
sk-ut-1b cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.234016
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.332294
Respiratory system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
Secondary motor area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08395
Acute Myeloid Leukemia_LAML_TCGA-AB-2891-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.719015
intermediate part of isB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0285
response to organic cyclic compound	GO Biological Process Annotations 2015	1.0	null
agonists	GeneRIF Biological Term Annotations	1.0	null
gallbladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.122766
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.751497
CRCGN008_HEPG2_24H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.8771
Peptide GPCRs(Mus musculus)	WikiPathways Pathways 2014	1.0	null
GSE198165,GSE198166_9_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
endocrine organ benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.871234
CRCGN013_HEPG2_24H:B07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.79679
DNAJC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90933
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.973653
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26079895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78791
RCC-FG2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.28
BEND6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39567
BRD-K17107214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08437
layer 5 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0644
betulinic acid-4101	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Thyroid gland medullary carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.762
ZSCAN32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8728
Diazinon	CTD Gene-Chemical Interactions	1.0	null
GSE126345_11_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13441
abnormal interleukin secretion	MPO Gene-Phenotype Associations	1.0	null
BRD-K96958073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91957
sublayer 6b of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15355
VMRC-LCD	COSMIC Cell Line Gene CNV Profiles	1.0	2.08712
organic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
movement of cell or subcellular component	GO Biological Process Annotations 2015	1.0	null
BRD-K82842087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06716
PRL-2915	DGIdb Drug Targets 2026	1.0	0.504114
TM-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.075
Hippocampal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21173
BRD-K27610371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19159
CRCGN016_MCF10A.WT.HP_24H:N15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.1152
cerebral gray matter	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.184959
trioxysalen-2516	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine	GeneRIF Biological Term Annotations	1.0	null
Ras guanyl-nucleotide exchange factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.203
Serotonergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.663
BRD-K46641047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0404
BRD-K14416602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9691
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.3724
Autonomic nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.176024
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.867546
outlet	GeneRIF Biological Term Annotations	1.0	null
Childhood Acute Lymphoblastic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
Hyperinsulinemic hypoglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
Orbital area, ventrolateral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2498
BRD-K35909757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00868
NDUFA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01001
Large cell neuroendocrine carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.815
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SETD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.58792
BRD-K60052521	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06962
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3456-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K27554804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09285
SUZ12-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
ACN	GDSC Cell Line Gene Expression Profiles	-1.0	-1.89674
precentral gyrus, right, bank of the precentral sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.839999
SUZ12-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
edema	MGI Mouse Phenotype Associations 2023	1.0	null
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.2929
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894595
BRD-K52863921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61426
not applicable_Hypothermia_GSE54229_131_mouse_Embryonic fibroblas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.289226
H3K9me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
carbenoxolone-4093	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A_48H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18375
Anteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34162
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.71477
liminal part of the r7 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04798
negative regulation of nucleotide metabolic process	GO Biological Process Annotations 2015	1.0	null
sst4	GeneRIF Biological Term Annotations	1.0	null
pancreatic islet	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.270561
BRD-K04367224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32263
r7 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69783
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Z-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7589-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
malignant	GeneRIF Biological Term Annotations	1.0	null
Metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.171
U0125-663	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
[L-Tyr<sup>8</sup>]CYN 154806	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
Cardiomegaly	CTD Gene-Disease Associations	1.0	1.26236
Epithelial Ovarian Cancer	DisGeNET Gene-Disease Associations	1.0	null
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Subiculum, ventral part, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00686
TP63	ChEA Transcription Factor Targets	1.0	null
HUP-T4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16606
receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.055129
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5381
NCIH520	CCLE Cell Line Gene CNV Profiles	-1.0	-1.99584
Renin Induced Hypertension	DisGeNET Gene-Disease Associations	1.0	null
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.18935
BRD-K78082598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22588
Depressed Mood	DisGeNET Gene-Phenotype Associations	1.0	null
Cardiac stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.579
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.5699
mantle zone of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02936
SNU46	CCLE Cell Line Gene CNV Profiles	1.0	1.94676
Cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.113
PROCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85179
BRD-K88099511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50896
sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061154
[<sup>125</sup>I]CGP 23996	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7314-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75825
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21139023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69471
Sense organ	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.4
JARID2-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:D17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.72173
valproic acid-347	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Renal Sclerosis With Hypertension	DisGeNET Gene-Disease Associations	1.0	null
NCIH1666	CCLE Cell Line Gene CNV Profiles	1.0	1.80693
lateral wings of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06008
positive regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
Pseudomyxoma Peritonei	DisGeNET Gene-Disease Associations	1.0	null
BRD-K91191855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12846
BRD-K00793226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61519
periventricular stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73868
GSE92965_0_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
STOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08361
response to chemical	GO Biological Process Annotations 2015	1.0	null
Multiple Chronic Conditions	DisGeNET Gene-Disease Associations	1.0	null
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.695103
NZM7	DepMap CRISPR Gene Dependency	1.0	2.10984
Foregut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.172
GABPA	ENCODE Transcription Factor Targets	1.0	null
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.848003
para-abducens nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11028
tolfenamic acid-5454	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8421-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Triple-Negative Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K82102697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86609
ebselen-2717	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
Piriform area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.873
BRD-K38574421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64978
GSE101537_4_v_2_neurog3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular response to organic cyclic compound	GO Biological Process Annotations 2015	1.0	null
BRD-K58333451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09925
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1038
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.227
surgically	GeneRIF Biological Term Annotations	1.0	null
NCIH2444	CCLE Cell Line Gene CNV Profiles	1.0	2.36326
positive regulation of mapk cascade	GO Biological Process Annotations 2015	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
Substance abuse	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
Lung adenocarcinoma_LUAD_TCGA-44-6778-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.24052
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.43375
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.56175
BRD-K64958595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26701
BRD-K56520977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58938
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.59609
ovary cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.078581
laryngeal	GeneRIF Biological Term Annotations	1.0	null
Cyst wall	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.557
planum polare, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04338
Adult Erythroleukemia	DisGeNET Gene-Disease Associations	1.0	null
thalidomide-1411	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
rotenone-5948	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
Anterior cingulate area, ventral part, 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31624
NHEK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
SUZ12-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-51-4081-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
bone cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05614
Sensorineural Hearing Loss (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
BRD-K74823284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16828
bone marrow cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071465
SMAD1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5973-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0647
YMB-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10248
NCIH2291	CCLE Cell Line Gene CNV Profiles	-1.0	-2.16336
oxybenzone-6469	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K52973286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25285
SKIDA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02125
cyclocytidine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07553
U-937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54995
response to organonitrogen compound	GO Biological Process Annotations 2015	1.0	null
intermediate stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10553
Carcinoma, Ovarian Epithelial	DisGeNET Gene-Disease Associations	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13575
Primary Pigmented Nodular Adrenal Dysplasia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K96604397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38374
alzheimer	GeneRIF Biological Term Annotations	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8336-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
guanfacine-5621	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Mz-ChA-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
Meningothelial meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
CRCGN014_HEPG2_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9739
Somatosensory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.075
OVTOKO	CCLE Cell Line Gene Expression Profiles	1.0	1.71353
clone15c4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
PHC1-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
islands	GeneRIF Biological Term Annotations	1.0	null
Subiculum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.906
GSE156907,GSE160237_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE178560_0_v_1_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
basal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.585625
Withdrawal Symptoms	DisGeNET Gene-Phenotype Associations	1.0	null
CRCGN009_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	8.67555
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OB-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RARG	ChEA Transcription Factor Targets	1.0	null
benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.954525
[125I]TYR10-CST14	DGIdb Drug Targets 2026	1.0	0.302469
H-C[CYS-PHE-LAGL(N&BETA;ME,BENZOYL)-DTRP-LYS-THR-PHE-CYS]-OH	DGIdb Drug Targets 2026	1.0	1.51234
Islet cell tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.828
BRD-K73524144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00461
degree	GeneRIF Biological Term Annotations	1.0	null
stufy	GeneRIF Biological Term Annotations	1.0	null
prostate	GeneRIF Biological Term Annotations	1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
BRD-K90793170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43623
SNU324	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74553
follicular adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.6791
SUZ12	ChEA Transcription Factor Targets	1.0	null
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.315729
effects	GeneRIF Biological Term Annotations	1.0	null
Peeling skin syndrome 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
daunorubicin-7507	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AR-35413990-HUMAN-ARPOSCRPROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
Major Depressive Disorder	DisGeNET Gene-Disease Associations	1.0	null
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
pituitary gland tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.916069
cell type benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.964148
Human Immunodeficiency Virus	DisGeNET Gene-Disease Associations	1.0	null
ARVCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97977
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38129
BRD-A57762296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04342
Glucagonoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.373
LCAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28264
acetylsalicylic acid-2664	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tanespimycin-450	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE205070_1_v_4_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX17	ChEA Transcription Factor Targets	1.0	null
decreased grip strength	MGI Mouse Phenotype Associations 2023	1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.46017
amygdala	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.481648
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16316
H3255	COSMIC Cell Line Gene CNV Profiles	1.0	2.08712
Status Epilepticus	CTD Gene-Disease Associations	1.0	2.88009
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03936
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BIM 23052	DGIdb Drug Targets 2026	1.0	0.302469
CRCGN015_HEPG2_48H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.91148
RNF2	ChEA Transcription Factor Targets	1.0	null
SK-MEL-3	GDSC Cell Line Gene Expression Profiles	-1.0	-2.00367
Retrosplenial area, lateral agranular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08112
Metaplasia	CTD Gene-Disease Associations	1.0	1.20163
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040913
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
obstruction	GeneRIF Biological Term Annotations	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.12527
Insulinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.075
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
bucladesine-5886	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cardiac Arrest	DisGeNET Gene-Disease Associations	1.0	null
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.20088
GSE113817_0_v_1_bach1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Subiculum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30316
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
proadifen-2707	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cellular response to corticosteroid stimulus	GO Biological Process Annotations 2025	1.0	null
OCTREOTIDE ACETATE	DGIdb Drug Targets 2026	1.0	0.302469
Simple Partial Status Epilepticus	DisGeNET Gene-Phenotype Associations	1.0	null
flurbiprofen-6472	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PTGIS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84222
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.951659
BRD-K48681121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29314
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35431
Leydig cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.066
CRCGN012_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4818
nafcillin-3983	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K38788176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61825
CEBPD-23245923-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ligand	GeneRIF Biological Term Annotations	1.0	null
Insulinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.683
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.0688
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937535
Lung adenocarcinoma_LUAD_TCGA-44-5645-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
valproic acid-5600	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intermediate part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.188
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.282483
BRD-K20373726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49002
GRK1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K07812227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.26876
negative regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
Blood sugar levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2699
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
HMGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98031
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38584
eyelid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.178906
cytostatic	GeneRIF Biological Term Annotations	1.0	null
Recurrent Tumor	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K58219783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2293
sublayer 6b of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09911
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.73803
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
increased tumor necrosis factor secretion	MGI Mouse Phenotype Associations 2023	1.0	null
&BETA;3-TETRAPEPTIDE	DGIdb Drug Targets 2026	1.0	1.51234
GSE185944_5_v_4_pth1r_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amprolium-4241	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GRM	CCLE Cell Line Gene CNV Profiles	1.0	1.42749
Retrosplenial area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66139
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08996
Mesothelioma_MESO_TCGA-LK-A4O2-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6906
blood	GeneRIF Biological Term Annotations	1.0	null
BRD-K01371603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20781
HCC1954	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98681
BRD-K41762421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66925
alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.173832
CRCGN017_MCF10A.TP53.M_24H:N16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.30195
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A465-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.867222
alimentary canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.546533
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.95636
BRD-K70276322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3987
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
whereas	GeneRIF Biological Term Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A3JM-01A-12R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73577714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01294
PARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58461
Oxazolone	CTD Gene-Chemical Interactions	1.0	null
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
RNF2-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MDA-MB-435S cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.97
BRD-K43411248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01153
Perturb_657_KD_lncRNA_141992_SRP093784	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.06069
beta-escin-2194	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H510A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
L-362 855	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
BRD-K03852663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66317
hyperalgesia	MGI Mouse Phenotype Associations 2023	1.0	null
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.850572
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058634
GSE118794_5_v_4_zmynd8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.64341
Hormone producing pituitary cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.13
Tube foot	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.57
intracellular part	GO Cellular Component Annotations 2015	1.0	null
DLD1	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.867222
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15341710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32243
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC7938710__F3	PFOCR Pathway Figure Associations 2024	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64565
response to organic substance	GO Biological Process Annotations 2015	1.0	null
EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Colon descendens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.598
SRIF-28	DGIdb Drug Targets 2026	1.0	0.252057
Dorsal peduncular area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37088
BRD-K15882320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71772
estrone-6448	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
c-MYC_KD_GDS2526_113_human_MDA-MB-231 BREAST CANCER cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
g-protein coupled receptor activity	GO Molecular Function Annotations 2015	1.0	null
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.78424
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsalstriatum	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.868511
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-2.0876
Infralimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35381
CRCGN008_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8789
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16018
Ammon's horn	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57308
FOXA1-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.196339
gallbladder	GeneRIF Biological Term Annotations	1.0	null
rko cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.341863
neuropeptide signaling pathway	GO Biological Process Annotations 2023	1.0	null
OGFRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61361
BON-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.217
[L-TYR8]CYN 154806	DGIdb Drug Targets 2026	1.0	0.302469
embryoday7.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.014
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BIM 23627	DGIdb Drug Targets 2026	1.0	0.302469
trimethobenzamide-4180	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Anterior cingulate area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0972
ginkgolide A-4002	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Atherosclerosis	DisGeNET Gene-Disease Associations	1.0	null
sebaceous gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.393442
GNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50999
GPCRs, Class A Rhodopsin-like(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
L-methionine sulfoximine-4070	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Infralimbic area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42221
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828914
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.18516
BRD-K69903198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30953
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
amylocaine-4089	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
meclozine-5607	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Intestinal schistosomiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33865
BRD-K11227160	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48027
adenohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.180822
EBF1-22473956-BONE-MARROW-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pentetic acid-5629	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
neuropeptide binding	GO Molecular Function Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46I-01A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K32251128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48935
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0456
periventricular stratum of r3Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12553
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043371
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.909703
Psammoma body	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
cell-cell signaling	GO Biological Process Annotations 2015	1.0	null
G protein-coupled receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.005
BRD-K33865795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02634
Nucleus accumbens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.224
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35507
ESRRB-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27886
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BX-01A-31R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pparg::Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.7899
L-362,855	DGIdb Drug Targets 2026	1.0	0.302469
Papillary carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
Symmetric synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.129
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.867546
novobiocin-576	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skull base meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08345
CRCGN017_MCF10A.WT.HP_24H:E04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.08816
GSE143643,GSE143644_2_v_5_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.742564
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Thyroid gland follicular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937535
brain	GTEx Tissue Gene Expression Profiles	1.0	2.12679
integument phenotype	MPO Gene-Phenotype Associations	1.0	null
Alanine aminotransferase (ALT) levels after remission induction therapy in actute lymphoblastic leukemia (ALL)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
periventricular stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04075
STAT5B-24692510-EPITHELIUM-MOUSE-MAMMARY	ChEA Transcription Factor Targets 2022	1.0	null
cpg	GeneRIF Biological Term Annotations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6627
Prostatic Neoplasms	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K79264000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34461
node	GeneRIF Biological Term Annotations	1.0	null
NCIH2004RT	DepMap CRISPR Gene Dependency	1.0	3.4544
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A5SQ-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.13767
Peripheral nervous system neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.221
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37442
orlistat-6388	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
g-protein coupled receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.145334
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.856846
CRCGN008_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7764
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1MP-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Spinal canal and spinal cord meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.152
VIPoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.7
cellular response to nitrogen compound	GO Biological Process Annotations 2015	1.0	null
Primary somatosensory area, trunk, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02436
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955717
Myocardial Infarction	DisGeNET Gene-Disease Associations	1.0	null
HD-MY-Z	GDSC Cell Line Gene Expression Profiles	-1.0	-1.69486
CRCGN017_MCF10A.WT.HP_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8965
SMAD4	ChEA Transcription Factor Targets	1.0	null
CtIP_DEPLETION_GDS2189_122_human_MCF10A mammary epithelial cells (MECs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.04204
NNC269100	DGIdb Drug Targets 2026	1.0	1.51234
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33696
Retinitis Pigmentosa	DisGeNET Gene-Disease Associations	1.0	null
PHC1-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
496100536_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.20263
Prostate adenocarcinoma_PRAD_TCGA-EJ-5525-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
naltrindole-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30207
Hypertrophy	CTD Gene-Disease Associations	1.0	1.42913
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057421
Memory Disorders	CTD Gene-Disease Associations	1.0	1.32637
Depression	DisGeNET Gene-Phenotype Associations	1.0	null
Primary Malignant Neoplasm Of Lung	DisGeNET Gene-Disease Associations	1.0	null
Endocrine organ benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.308
increased airway responsiveness	MPO Gene-Phenotype Associations	1.0	null
LS1034	DepMap CRISPR Gene Dependency	1.0	2.17028
Neuroendocrine tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.514
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.801
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
explaining	GeneRIF Biological Term Annotations	1.0	null
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43396
BRD-K62472719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78094
layer 2 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00643
adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.04167
locomotion	GO Biological Process Annotations 2015	1.0	null
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65112
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
CRCGN014_HEPG2_3H:B08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7984
HDMYZ	DepMap CRISPR Gene Dependency	1.0	2.37226
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.004
hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094163
RCM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0022
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
11707567-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
Fatty Liver	DisGeNET Gene-Disease Associations	1.0	null
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.171036
BIM 23052	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
abnormal hematopoiesis	MPO Gene-Phenotype Associations	1.0	null
MAN1A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7068
response to corticosteroid	GO Biological Process Annotations 2015	1.0	null
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5939-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K47784262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35921
predictor	GeneRIF Biological Term Annotations	1.0	null
CRCGN015_HEPG2_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.6119
Sublaterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10832
Acute Myeloid Leukemia_LAML_TCGA-AB-2908-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
negative regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Intestinal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.13
small molecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Edema	CTD Gene-Disease Associations	1.0	1.45723
CRCGN015_MCF10A.TP53.M_24H:K11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06255
planum temporale, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.902532
BL-70	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Thyroid gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.63
Prestwick-864-3994	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r2 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72174
Acute Myeloid Leukemia_LAML_TCGA-AB-2982-03B-01T-0748-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059219
AtT-20 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.686
Lung squamous cell carcinoma_LUSC_TCGA-22-5478-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
arachidonic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
Colon Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
anatomical structure development	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.16338
Hyperglycemia	DisGeNET Gene-Disease Associations	1.0	null
insulinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.577716
colorectal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.268482
DPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86726
layer 6a of PaS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01209
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
morphine_mus musculus_gpl6246_gse17731	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
BRD-K27384243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24653
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08635
neuropeptide signaling pathway	GO Biological Process Annotations 2025	1.0	null
TASK1	DepMap CRISPR Gene Dependency	1.0	5.97931
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_3H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.66475
PHETA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89823
WM983B	CCLE Cell Line Gene CNV Profiles	1.0	1.67314
ZNF701	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	121.948
OLIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23616
SNU349	CCLE Cell Line Gene Expression Profiles	1.0	1.55518
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pilocarpine	CTD Gene-Chemical Interactions	1.0	null
Immune system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.186
Secretory meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
BRD-K61821542	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35747
Cytoplasmic side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.108
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.688168
Median nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.041
CRCGN013_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65176
HO1U1	DepMap CRISPR Gene Dependency	1.0	2.46443
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4837-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63908919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20815
abnormal touch/ nociception	MPO Gene-Phenotype Associations	1.0	null
BRD-K31010207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10666
G alpha (i) signalling events	Reactome Pathways 2024	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ML-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51677
Carcinogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5691-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1857
Ovarian Failure, Premature	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K66717300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39781
Medullary carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.901
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A299-01A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13227
Acute Myeloid Leukemia_LAML_TCGA-AB-2980-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.688
higher	GeneRIF Biological Term Annotations	1.0	null
GSE97275,GSE97280_0_v_1_zmynd11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Orbital area, medial part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35615
RUNX1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE139966_1_v_2_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
greatest	GeneRIF Biological Term Annotations	1.0	null
Adrenal gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.749
Prostate adenocarcinoma_PRAD_TCGA-KC-A7FE-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K07029108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53801
paracentral lobule, anterior part, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.85311
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36764776	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24836
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894081
FNBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55131
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
outer SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.866457
ZFX-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
PMC10778465__F1	PFOCR Pathway Figure Associations 2024	1.0	null
citalopram-3820	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AMO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
metastasis	GeneRIF Biological Term Annotations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4490-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.23743
FSP27_KO_GDS3768_514_mouse_White adipose tissue  (WAT)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.18136
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19969
BRD-K16717067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16081
r5 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33358
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
striatum_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.13598
496100384_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35893
HCC1500	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ARL4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95341
BRD-A89554862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62771
acromegaly	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.642221
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0233
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Dorsomedial nucleus of the hypothalamus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73685
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7881-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Triple Negative Breast Neoplasms	DisGeNET Gene-Disease Associations	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.860326
Retinoid Dermatitis	DisGeNET Gene-Disease Associations	1.0	null
treatment	GeneRIF Biological Term Annotations	1.0	null
hecogenin-2716	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ovary	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.469987
H3K9me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GPCRs, Class A Rhodopsin-like(Mus musculus)	WikiPathways Pathways 2014	1.0	null
[125I]LTT-SRIF-28	DGIdb Drug Targets 2026	1.0	0.302469
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08433
gastrointestinal cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061217
amide binding	GO Molecular Function Annotations 2015	1.0	null
ChIP_SUZ12_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Stomach Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6012-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.966291
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.40036
BRD-K97638135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97364
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KE39	CCLE Cell Line Gene CNV Profiles	1.0	1.38974
bretylium tosilate-3394	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.927489
adult	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.284253
superficial stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01914
BRD-A14803952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00108
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5705-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.648
BRD-K04147413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50986
FICD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52566
glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.222938
CRCGN014_HEPG2_24H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.66789
carbarsone-3991	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE138001_2_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
BRD-K49570068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40066
p3 portion of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56414
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
CRCGN014_HEPG2_3H:A05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00601
neuroendocrine tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.814693
Pancreatic alpha cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.481
Laminated body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.812
chr20_23039366_A_G_b38	GTEx eQTL 2025	1.0	1.56203
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112714_2_v_3_ctnnb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Enteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.971
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.168101
Field CA1, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86013
ependymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.345558
Experimental Organism Basal Cell Carcinoma	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K24076516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16507
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6827-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Amyotrophic lateral sclerosis (sporadic)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.604576
BRD-K06475437	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06237
JARID2-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Pancreatic delta cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.137
long-chain fatty acid metabolic process	GO Biological Process Annotations 2015	1.0	null
hyperalgesia	MPO Gene-Phenotype Associations	1.0	null
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825571
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25434
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.278955
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K88955481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01704
Schizophrenia	DisGeNET Gene-Disease Associations	1.0	null
Perturb_11784_KO_Blk_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.04088
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.00822
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.39592
brain cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064894
32d cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.606916
PMC7305081-10120_2020_1045_MOESM1_ESM.xlsx-Tab2-Mutation-MAF_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
FNIP-folliculin RagC/D GAP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.76
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.870532
BCPAP	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95117
Atherosclerosis	CTD Gene-Disease Associations	1.0	1.12668
Aortic Valve Insufficiency	DisGeNET Gene-Disease Associations	1.0	null
Genetic Hypertension	DisGeNET Gene-Disease Associations	1.0	null
TT cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.705
SUZ12	ENCODE Transcription Factor Targets	1.0	null
Diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.403
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.56443
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Essential Hypertension	DisGeNET Gene-Disease Associations	1.0	null
Bulimia	DisGeNET Gene-Disease Associations	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.953318
ChIP_JARID2_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
sstr5	GeneRIF Biological Term Annotations	1.0	null
probenecid-4771	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Colorectal Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
CRCGN014_HEPG2_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78109
CRCGN017_MCF10A.WT.HP_24H:K22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26895
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE100102_2_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal acute inflammation	MPO Gene-Phenotype Associations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2929-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
layer 4 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27902
Bronchopulmonary Dysplasia	DisGeNET Gene-Disease Associations	1.0	null
JARID2-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.9933
BRD-K45978015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56679
thyroid medullary carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.357814
cannot	GeneRIF Biological Term Annotations	1.0	null
Schizoaffective Disorder	DisGeNET Gene-Disease Associations	1.0	null
Meningococcal infection_Umbilical vein_GSE4646	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.47645
Kallmann Syndrome	DisGeNET Gene-Disease Associations	1.0	null
SKNSH	DepMap CRISPR Gene Dependency	1.0	2.03417
BRD-K86228587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16822
regulation of nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K57586808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.91064
Rectum adenocarcinoma_READ_TCGA-EI-6512-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.885136
Sarcoma_SARC_TCGA-X6-A8C7-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78836
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4116-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1373	CCLE Cell Line Gene Expression Profiles	1.0	1.4193
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3362-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CUTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00712
angular gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.923067
Prostate Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC12836574-mmc1.pdf-1-SOX10_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4723-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leiomyosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.139266
posteroventral (inferior) parietal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.828352
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.998235
stomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.289582
superficial stratum of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36144
teh	GeneRIF Biological Term Annotations	1.0	null
CRCGN014_HEPG2_3H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89585
colorectum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065612
Lung adenocarcinoma_LUAD_TCGA-55-6971-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Endothelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.022
NR3C1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K21180458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30683
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24226
diflunisal-1490	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Viscus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.383
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3351-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, unassigned, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27789
BRD-K11873306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44613
r10 portion of the hypoglossal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01753
neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.115723
miapaca-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.401007
phenacetin-3992	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TTT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.793
amitriptyline-5453	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K22145792	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01691
BRD-K62372121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07897
GSE199899_1_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Hindgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.881
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
RBPJ	ChEA Transcription Factor Targets	1.0	null
Tick Fever	DisGeNET Gene-Disease Associations	1.0	null
J-2156	DGIdb Drug Targets 2026	1.0	1.51234
Vitelline membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.559
HO-1-U-1	COSMIC Cell Line Gene CNV Profiles	1.0	2.08712
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
LGMN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50079
pdx1_22135308_duodenum_lof_mouse_gpl1261_gds4348	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.01259
GPCR downstream signaling	Reactome Pathways 2014	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-L3-A524-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
core of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88251
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chronic Heart Failure	DisGeNET Gene-Disease Associations	1.0	null
Climbing fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.609
regulation of cyclic nucleotide metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K29039402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06471
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828914
layer 6 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16256
gastrointestinal tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.564434
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.532
murine	GeneRIF Biological Term Annotations	1.0	null
BRD-K37262603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36057
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cd26	GeneRIF Biological Term Annotations	1.0	null
BRD-K59392325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10858
BRD-K50114736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21314
PRDM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05036
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99097591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19985
adenohypophysis tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.751645
response to glucocorticoid	GO Biological Process Annotations 2025	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.364
CTV-1	GDSC Cell Line Gene Expression Profiles	1.0	1.43652
response to peptide	GO Biological Process Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AD-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Hemangioblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.181
CRCGN016_MCF10A.WT.HP_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.2301
BRD-K58787433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32053
BRD-K98731550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68782
TRIM28	ChEA Transcription Factor Targets	1.0	null
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.605709
CRCGN015_HEPG2_48H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.77795
Humoral Hypercalcemia Of Malignancy (Disorder)	DisGeNET Gene-Disease Associations	1.0	null
SLR23	CCLE Cell Line Gene Expression Profiles	1.0	1.46596
PMC12211354-12915_2025_2224_MOESM6_ESM.xlsx-Sheet1-Sheet1_The_source_list_of_zebrafish_Npas4b_targets_from_human_NPAS4_targets_in_CHEA3_database_NPAS4	Rummagene Transcription Factor Associations 2026	1.0	null
throat	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.540188
Gastric gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.85
pituitary gland cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.825268
NCI-H187	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EVSA-T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.66501
neck	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.487886
response to oxygen-containing compound	GO Biological Process Annotations 2015	1.0	null
BRD-K88467167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10769
Carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.692
sstr1	GeneRIF Biological Term Annotations	1.0	null
BRD-K58491882	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36692
Asthma	DisGeNET Gene-Disease Associations	1.0	null
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.58613
LU-135	COSMIC Cell Line Gene CNV Profiles	1.0	2.08712
BRD-K91962463	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.33219
carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.648138
GOTO	GDSC Cell Line Gene Expression Profiles	-1.0	-2.98905
cellular response to hormone stimulus	GO Biological Process Annotations 2015	1.0	null
myosmine-4759	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
negative regulation of phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.0248
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09658
CRCGN017_MCF10A.TP53.M_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.3702
endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.240826
CRCGN013_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.30447
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3_OE_GDS3444_576_mouse_Cultured embryonic stem (ES) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Ventromedial hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD)	Reactome Pathways 2014	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.314839
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08066
positive regulation of intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
cell projection	GO Cellular Component Annotations 2015	1.0	null
regulation of cell proliferation	GO Biological Process Annotations 2015	1.0	null
KIF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.234
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5502
abnormal airway responsiveness	MPO Gene-Phenotype Associations	1.0	null
BRD-K83297764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12352
Death	CTD Gene-Disease Associations	1.0	1.06625
sublayer 6b of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33816
tiaprofenic acid-4091	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCIH2009	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78751
Large intestine cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.108
CRCGN016_MCF10A.WT.HP_24H:C07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.79471
Hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.074
CGP 23996	DGIdb Drug Targets 2026	1.0	0.302469
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K37929710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74244
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38717
SKBR3	CCLE Cell Line Gene CNV Profiles	1.0	1.32754
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
BRD-K38519585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21831
OCM-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.594
layer 6b of RSC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02875
upregulated	GeneRIF Biological Term Annotations	1.0	null
Primary visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34045
developmental process	GO Biological Process Annotations 2015	1.0	null
NMYC-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
olfactory tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.581218
PU.1-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8755441-mmc3.xlsx-IRF7-Up-SUZ12_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Diarrhea	DisGeNET Gene-Phenotype Associations	1.0	null
CRCGN010_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53017
BRD-K95577144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09716
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BF-01B-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H-c[DCys-Phe-LAgl(N<sup>&beta;</sup>Me benzoyl)-DTrp-Lys-Thr-Phe-Cys]-OH	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
NZM3	DepMap CRISPR Gene Dependency	1.0	3.05425
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.967042
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17115
Habenula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.089
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.908763
PHC1	ChEA Transcription Factor Targets	1.0	null
Posterior polymorphous corneal dystrophy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
Autosomal Dominant Hypocalcemia	DisGeNET Gene-Disease Associations	1.0	null
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BL-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82882121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.90357
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.79721
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
increased interleukin-1 beta secretion	MGI Mouse Phenotype Associations 2023	1.0	null
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.861049
neuron projection	GO Cellular Component Annotations 2023	1.0	null
musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047588
SUM52PE	DepMap CRISPR Gene Dependency	1.0	3.63801
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4881-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal type iv hypersensitivity reaction	MPO Gene-Phenotype Associations	1.0	null
single-organism metabolic process	GO Biological Process Annotations 2015	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05543
adrenal gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.477151
SUPM2	DepMap CRISPR Gene Dependency	1.0	6.27683
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39534
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.0099
adenylyl	GeneRIF Biological Term Annotations	1.0	null
H-EMC-SS	GDSC Cell Line Gene Expression Profiles	-1.0	-2.18457
H9 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.850034
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10299
Brain Lower Grade Glioma_LGG_TCGA-HT-7694-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN014_HEPG2_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01094
mantle zone of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01836
superior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.630718
BRD-K56916066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51365
intracellular	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.628613
CRCGN015_MCF10A_48H:M16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.21585
BRD-K19501975	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76683
Perturb_8514_KO_Setd1b_SRP328849	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
SST	Pathway Commons Protein-Protein Interactions	1.0	null
Signal Transduction	Reactome Pathways 2014	1.0	null
cellular response to corticosteroid stimulus	GO Biological Process Annotations 2015	1.0	null
CRCGN016_MCF10A.TP53.M_24H:P12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2832
BRD-K46152990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13638
flucytosine-6690	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
neuron spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.353662
Posterolateral visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05161
r4 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4851
CRCGN014_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.86064
BRD-K37144511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08467
Kidney renal clear cell carcinoma_KIRC_TCGA-DV-5573-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal granulocyte physiology	MPO Gene-Phenotype Associations	1.0	null
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.587629
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	112.655
Familial (Fpah)	DisGeNET Gene-Disease Associations	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Anterior lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.744
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.7876
BRD-K89574562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02639
Cannabis Dependence	DisGeNET Gene-Disease Associations	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
most	GeneRIF Biological Term Annotations	1.0	null
3t3clonea31	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
periventricular stratum of r2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71988
BRD-K59851511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41615
canadine-4020	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K62965224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.39896
Mccune-Albright Syndrome	DisGeNET Gene-Disease Associations	1.0	null
bladder	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214765
496100487_HIP_probable Alzheimer's disease_no TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01512
cellular response to oxygen-containing compound	GO Biological Process Annotations 2015	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.54519
suprofen-4005	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE145915_0_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17115
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55362
CRCGN012_HEPG2_24H:D08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06675
regulation of camp metabolic process	GO Biological Process Annotations 2015	1.0	null
sstrs	GeneRIF Biological Term Annotations	1.0	null
srih	GeneRIF Biological Term Annotations	1.0	null
Hypertension	CTD Gene-Disease Associations	1.0	1.13621
OTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14817
Tcf12	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.4607
fludrocortisone-281	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SST	Guide to Pharmacology Protein Ligands of Receptors	1.0	null
Side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.123
GSS	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
Thyroid nodule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.611
GATA2_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.925452
CRCGN014_HEPG2_3H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14559
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045169
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.510992
PMC10959942-41525_2024_411_MOESM1_ESM.pdf-86-TCF15_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
fluticasone-4011	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12757
PMC8025515-12859_2021_4105_MOESM12_ESM.xlsx-PW1-gene_stable_id_PEG3	Rummagene Transcription Factor Associations 2026	1.0	null
Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09174
BRD-K99982687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79948
peptide binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K14020943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24469
BRD-K53508363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32916
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
benign	GeneRIF Biological Term Annotations	1.0	null
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.310149
internal female genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.481259
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.45575
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUDT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68763
BRD-K82814367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03732
bone marrow	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070672
Prostate adenocarcinoma_PRAD_TCGA-HC-A8D0-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Superior cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
ARL6IP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6275
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10052
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04744
subsequent	GeneRIF Biological Term Annotations	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58535
Peptide ligand-binding receptors	Reactome Pathways 2014	1.0	null
U87	BioGPS Cell Line Gene Expression Profiles	1.0	1.13867
single-organism process	GO Biological Process Annotations 2015	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Small cell lung cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
Secondary Malignant Neoplasm Of Bone	DisGeNET Gene-Disease Associations	1.0	null
COR-L321	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Signal Transduction	Reactome Pathways 2024	1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.33344
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.86394
different	GeneRIF Biological Term Annotations	1.0	null
Gut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.511
SW13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-A90249268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
UMUC1	CCLE Cell Line Gene Expression Profiles	1.0	2.00124
BRD-K07365255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07989
CRCGN017_MCF10A.WT.HP_24H:G01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0946
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
BRD-K42214389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32467
Field CA1, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81543
NCI-H1573	COSMIC Cell Line Gene CNV Profiles	1.0	2.08712
CRCGN016_MCF10A.TP53.M_24H:F05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.77202
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.31239
BRD-K89805341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01196
SOX2	ChEA Transcription Factor Targets	1.0	null
monorden-5216	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.270068
sarcoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068311
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.236
biological regulation	GO Biological Process Annotations 2015	1.0	null
somatostatin receptor activity	GO Molecular Function Annotations 2015	1.0	null
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.937535
clidinium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0119
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19484
uterine cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.077827
Chronic Lymphocytic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
BRD-K36855468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.39407
trichlormethiazide-2998	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CBFA2T2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12118
Infundibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.915
U937	CCLE Cell Line Gene CNV Profiles	1.0	2.1052
troleandomycin-3985	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28887
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.75814
Acute Myeloid Leukemia_LAML_TCGA-AB-2952-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K98637033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16097
BRD-K49707067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14799
BRD-K06784595	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18092
GSE123502,GSE123504_1_v_0_chd4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
response to stimulus	GO Biological Process Annotations 2015	1.0	null
lateral nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.57859
Islet Cell Tumor	DisGeNET Gene-Disease Associations	1.0	null
L-803,087	DGIdb Drug Targets 2026	1.0	1.51234
RVH421	CCLE Cell Line Gene Expression Profiles	1.0	1.39563
carboxylic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7297
Acrodyostosis	DisGeNET Gene-Disease Associations	1.0	null
Pituitary gland disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.489
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.9995
BRD-K82506716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23099
abnormal hematopoietic system physiology	MPO Gene-Phenotype Associations	1.0	null
SW954	DepMap CRISPR Gene Dependency	1.0	2.15831
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25382
GSE143499_0_v_1_gata6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.266
p2092	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.138
intermediate stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07164
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.10175
Alcohol use disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
HNF4A	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6482-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0797
pyramidal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.432608
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
T3M3	DepMap CRISPR Gene Dependency	1.0	5.00735
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.8986
Rhinovirus Infection	DisGeNET Gene-Disease Associations	1.0	null
TTNPB-451	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
close	GeneRIF Biological Term Annotations	1.0	null
BRD-A59009217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14154
cellular response to endogenous stimulus	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6147-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0285
Dorsal peduncular area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17173
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.9814
celecoxib-482	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
effect	GeneRIF Biological Term Annotations	1.0	null
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.0808
CRCGN014_HEPG2_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1827
Marijuana Abuse	DisGeNET Gene-Disease Associations	1.0	null
LY3556050	DGIdb Drug Targets 2026	1.0	1.51234
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.6273
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39X-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7695-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.641
mesothelioma	GeneRIF Biological Term Annotations	1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
BRD-K22778609	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2675
breast cancer; prostate cancer	GAD Gene-Disease Associations	1.0	null
phthalylsulfathiazole-5614	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
dendritic spine	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.367388
ACTH-secreting pituitary adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.784
SOX17-20123909-XEN-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20006
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nr1h2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.4673
Conn Adenoma	DisGeNET Gene-Disease Associations	1.0	null
precuneus, left, superior lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.920932
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Solitary fibrous tumor/hemangiopericytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
SOMATOSTATIN	DGIdb Drug Targets 2026	1.0	0.302469
BRD-K99250186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03263
corpus striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.449886
BRD-K63626200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12571
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78N-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
retroorbital	GeneRIF Biological Term Annotations	1.0	null
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62809
BL70	CCLE Cell Line Gene Expression Profiles	1.0	2.39431
spironolactone-6255	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
r4 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24801
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17406
Musculoskeletal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
Kidney Chromophobe_KICH_TCGA-KO-8415-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.77898
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.847706
prostatic	GeneRIF Biological Term Annotations	1.0	null
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
l-6 myoblast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.244232
molecular_function	GO Molecular Function Annotations 2015	1.0	null
CRCGN015_HEPG2_48H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.41778
MM485	DepMap CRISPR Gene Dependency	1.0	2.98018
CRCGN010_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.1349
Alcohol dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.265
CRCGN016_MCF10A.TP53.M_24H:O20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.49105
r2 part of nucleus subcoeruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96471
SUZ12_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of nucleotide metabolic process	GO Biological Process Annotations 2015	1.0	null
Hereditary Sensory Autonomic Neuropathy	DisGeNET Gene-Disease Associations	1.0	null
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.826688
localization	GeneRIF Biological Term Annotations	1.0	null
purkinje layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.320591
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66413
Lung adenocarcinoma_LUAD_TCGA-50-6595-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rxra	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.4097
Endocrine gland cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.062
NAMALWA	CCLE Cell Line Gene Expression Profiles	1.0	1.76427
BRD-K76921877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25651
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.146
Pancreatic cystadenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.068
GPCRs class A rhodopsin like	WikiPathways Pathways 2024	1.0	null
endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.09422
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
colon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059971
BRD-K24532680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41598
CRCGN015_MCF10A.WT.HP_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.919
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SC-58125-542	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.019394
diloxanide-3399	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN009_HEPG2_24H:L07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.6589
ChIP_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CRCGN014_HEPG2_3H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.1632
OE33	GDSC Cell Line Gene Expression Profiles	1.0	1.61634
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.76
skeletal muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.071288
ABC1	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
pilocarpine-6741	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GPCR downstream signalling	Reactome Pathways 2024	1.0	null
Atherothrombosis	DisGeNET Gene-Disease Associations	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.14121
Paget Disease	DisGeNET Gene-Disease Associations	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063464
496100443_HIP_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.15137
Lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.178
496100657_FWM_probable Alzheimer's disease_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.40865
CAPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29796
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.63111
Neuroendocrine tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.782
R-atenolol-2496	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CPC-N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00623
CRCGN014_HEPG2_3H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.09612
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227445
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12263
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.888044
HUH-6-CLONE5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Parotid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.918
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7038
POR_KO_GDS1678_762_mouse_Jejunum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Carcinoma Of Lung	DisGeNET Gene-Disease Associations	1.0	null
Retinoblastoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-A39521712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15039
NCI-H510A	COSMIC Cell Line Gene CNV Profiles	1.0	2.08712
Liver Diseases	CTD Gene-Disease Associations	1.0	1.45617
SOX2-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Field CA2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35439
Prolactinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.931
superficial stratum of CCx (cortical plate/marginal zone)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01951
PMC8638098__F6	PFOCR Pathway Figure Associations 2024	1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
schistosomiasis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.136601
CRCGN015_MCF10A.WT.HP_24H:K18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.91873
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61201
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.382
AKT1_knockout_214_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.41126
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02918
r10 part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19095
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.43696
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dorsal motor nucleus of the vagus nerve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31642
evaluate	GeneRIF Biological Term Annotations	1.0	null
Fetal Death	CTD Gene-Disease Associations	1.0	1.21599
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal hypersensitivity reaction	MPO Gene-Phenotype Associations	1.0	null
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.592444
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.841482
alpha-ergocryptine-3817	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.140125
BRD-K28320832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21804
doxylamine-4235	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
iloprost-496	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
niclosamide-4018	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7920-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease	Reactome Pathways 2014	1.0	null
Skin Endocrine Disorder	DisGeNET Gene-Disease Associations	1.0	null
BRD-K63573625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51067
r3 part of parvicellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15094
Medial entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.709
Adrenal gland hyperfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.784
NCIH854	CCLE Cell Line Gene CNV Profiles	1.0	1.68717
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCOR-22465074-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PLEKHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61111
immunohistochemistry	GeneRIF Biological Term Annotations	1.0	null
Meningioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.173
DES-AA5-[D-TRP8]SRIF	DGIdb Drug Targets 2026	1.0	0.378086
BRD-K01995700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87157
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuron projection	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
negative regulation of phosphate metabolic process	GO Biological Process Annotations 2015	1.0	null
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.073274
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A12J-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-8224-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Non-Small Cell Lung Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K45576113	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04086
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.25414
r10 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.54061
myoblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.151574
KRAS.PROSTATE_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
RAB3A_KO_GDS2482_706_mouse_Hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SIRT3_KO_GDS4058_454_mouse_BROWN ADIPOSE TISSUE	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-5933-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTC709	DepMap CRISPR Gene Dependency	1.0	2.3997
VMRCRCW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96571
abnormal granulocyte morphology	MPO Gene-Phenotype Associations	1.0	null
somatostatin	GeneRIF Biological Term Annotations	1.0	null
TBX20-22328084-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TC-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.146
Peeling skin syndrome 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.097
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21225
periventricular stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09907
NCIH1650	CCLE Cell Line Gene CNV Profiles	1.0	1.40058
BRD-K39460811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.58014
CRCGN015_HEPG2_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.28035
pralidoxime-5383	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Status Epilepticus	DisGeNET Gene-Disease Associations	1.0	null
KARPAS-299 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.572
CRCGN016_MCF10A.TP53.M_24H:N14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2012
Squamous Cell Carcinoma Of Skin	DisGeNET Gene-Disease Associations	1.0	null
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of CA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62622
inhibits	GeneRIF Biological Term Annotations	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.301
Lipopolysaccharides	CTD Gene-Chemical Interactions	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0027
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K83786559	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07249
sulfasalazine-6346	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN014_HEPG2_3H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.41909
abnormal neutrophil physiology	MPO Gene-Phenotype Associations	1.0	null
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62228
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17804
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PZ-01A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71339292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11109
CRCGN017_MCF10A.TP53.M_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05849
Cryptorchidism	DisGeNET Gene-Disease Associations	1.0	null
UterusCorpus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.959752
HN	GDSC Cell Line Gene Expression Profiles	1.0	2.32013
TBX20-22080862-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07285
Vibratory Urticaria	DisGeNET Gene-Disease Associations	1.0	null
Pyloric region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.05
RNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38815
CRCGN015_HEPG2_48H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.17561
pulmonary edema	MGI Mouse Phenotype Associations 2023	1.0	null
RL7	BioGPS Cell Line Gene Expression Profiles	1.0	1.53291
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.867427
prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.449947
respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CHL1DM	DepMap CRISPR Gene Dependency	1.0	2.05853
Primary somatosensory area, lower limb, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19866
Herpes Nos	DisGeNET Gene-Disease Associations	1.0	null
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06119
PU1-27457419-CHIP-SEQ-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ARNT	ChEA Transcription Factor Targets	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.954296
psych	GAD High Level Gene-Disease Associations	1.0	0.293278
BRD-K78681155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11251
ELF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1388
pleural	GeneRIF Biological Term Annotations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.319
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00694
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K98749544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1914
496100612_HIP_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16664
PPARG-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN009_HEPG2_24H:F20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.4227
BRD-K56343202	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12102
sublayer 6b of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0929
adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.65288
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
Frontoparietal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
OCT4-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Idiopathic Hypogonadotropic Hypogonadism	DisGeNET Gene-Disease Associations	1.0	null
CRCGN011_HEPG2_24H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9399
CTCF_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
BRD-K55209210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07091
flecainide-3937	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormal blood cell physiology	MPO Gene-Phenotype Associations	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.998204
Prelimbic area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27733
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
hyperpituitarism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.144711
palmatine-chloride	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30645
specific	GeneRIF Biological Term Annotations	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stratum radiatum of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.974087
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	71.2455
Hypogonadism	DisGeNET Gene-Disease Associations	1.0	null
perimammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50757
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	120.432
CRCGN009_HEPG2_24H:L08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.8197
BRD-K28545166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7948
phenelzine-3802	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PSN1	CCLE Cell Line Gene CNV Profiles	1.0	1.37764
ZNF813	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42297
SU-DHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16018
2-iminoacetate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.539
Chromophobe adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
BRD-K81035073	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1332
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5696-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
metabolic	GAD High Level Gene-Disease Associations	1.0	0.293278
Anterior cingulate area, ventral part, 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48931
Nephrogenic Syndrome Of Inappropriate Antidiuresis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K22672200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23984
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
Neuroectodermal tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.776
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.175745
BRD-K39223744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38283
CRCGN012_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6906
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
valproic acid-433	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
abnormal innate immunity	MPO Gene-Phenotype Associations	1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4324
CRCGN015_HEPG2_48H:B10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.43266
Serotonin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.846
Infralimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05116
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.654
Neuroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.772
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
analogs	GeneRIF Biological Term Annotations	1.0	null
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.80111
BRD-K90746817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10275
breast cancer	GAD Gene-Disease Associations	1.0	null
[<sup>125</sup>I]LTT-SRIF-28	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
pituitary cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.308842
BRD-K09168812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28412
CRCGN015_HEPG2_48H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.82666
exerted	GeneRIF Biological Term Annotations	1.0	null
Organ system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.178
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.992217
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.146
ERF::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.755
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5693-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of phosphorylation	GO Biological Process Annotations 2015	1.0	null
CRCGN014_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.31695
SW837	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44827
regulation of phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
PMC7029484-13041_2020_561_MOESM3_ESM.xlsx-Table_S8-Table_S8_The_extracted_upregulated_genes_in_SBMA-MNs_in_GSEA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.16426
Rectum adenocarcinoma_READ_TCGA-DC-5869-01A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51671
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.865171
Olfactory tubercle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.022
Liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.071
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.40677
islet cell tumor	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.529608
BRD-K91784140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3749
ACHN	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.23436
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
Bone Pain	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K69840402	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90238
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65627
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.03812
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
SF295	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.63007
BRD-K90951880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84384
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.530389
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.951794
H3K9me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.309613
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HG-A2PA-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventral tegmental area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01503
large intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05778
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.218398
k1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.189
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.90205
496100521_HIP_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.26749
Anaplasia	DisGeNET Gene-Disease Associations	1.0	null
Adrenocortical Hyperplasia	DisGeNET Gene-Disease Associations	1.0	null
respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.28294
abnormal homeostasis	MPO Gene-Phenotype Associations	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.955428
adult liver stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.59124
tolazamide-4003	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
sstr4	GeneRIF Biological Term Annotations	1.0	null
Inflammatory Pain	DisGeNET Gene-Phenotype Associations	1.0	null
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2836
Type 2 diabetes mellitus_Hepatic Tissue_GSE2899	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.62484
BRD-K31336762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35436
Lung adenocarcinoma_LUAD_TCGA-50-5936-11A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.19178
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6643-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
monorden-5952	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65177
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6142
BRD-K83244979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06354
BRD-K49211735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25527
internal male genital organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.535042
VIRMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2249
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5449
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Osteitis	DisGeNET Gene-Disease Associations	1.0	null
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861968
Hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.155
EPPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7226
NCIH1793	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34168
clopidol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70944
probucol-5626	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skull cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12263
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.42311
intermediate periretromammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.22339
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22537
BRD-K30977850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42139
BRD-K40474424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95855
Supramammillary nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42427
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S6-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K90157100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56379
Skull base cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
Forgetful	DisGeNET Gene-Phenotype Associations	1.0	null
LY6G5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17854
BRD-K97106314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95101
Leukemogenesis	DisGeNET Gene-Disease Associations	1.0	null
BRD-K08647020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19033
cortices	GeneRIF Biological Term Annotations	1.0	null
meibomian gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.431843
BRD-K80073743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16005
g-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	GO Biological Process Annotations 2015	1.0	null
HUP-T3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.18468
Lung adenocarcinoma_LUAD_TCGA-55-6975-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02684
MAP2K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18392
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Total Hypotrichosis, Mari Type	DisGeNET Gene-Disease Associations	1.0	null
periventricular stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1499
Hypoparathyroidism	DisGeNET Gene-Disease Associations	1.0	null
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19062
parasitic infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047343
state	GeneRIF Biological Term Annotations	1.0	null
Grand Mal Status Epilepticus	DisGeNET Gene-Disease Associations	1.0	null
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.66257
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.53379
regulation of purine nucleotide metabolic process	GO Biological Process Annotations 2015	1.0	null
TRIM28-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.05543
hematopoietic system phenotype	MPO Gene-Phenotype Associations	1.0	null
chr20_23031540_T_C_b38	GTEx eQTL 2025	1.0	1.19931
19074895-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
Biliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.126
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Hypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.218
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-506-MKX_MKX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Retrosplenial area, ventral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13509
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058392
RUNX1-22343733-KASUMI1-HUMAN-PERIPHBLOOD-AML	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral parabrachial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.62286
primary auditory cortex (core)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.87379
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090953
CRCGN015_MCF10A.TP53.M_24H:L09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.06195
HT1197	CCLE Cell Line Gene CNV Profiles	1.0	1.81823
CRCGN014_HEPG2_24H:H18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03053
procainamide-5663	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K86208187	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04739
ARNT-22903824-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Carney Complex	DisGeNET Gene-Disease Associations	1.0	null
Liver Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
inflammationinduced	GeneRIF Biological Term Annotations	1.0	null
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3973
Apicolateral plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.688
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21191
Multiple Myeloma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K67430561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.74346
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4912-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acromegaly	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.487
BICR16	DepMap CRISPR Gene Dependency	1.0	2.51269
outer SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03829
Neuroendocrine carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.708
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
lymphocytes	GeneRIF Biological Term Annotations	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
BRD-K80724972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69289
solanine-4087	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:O11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19091
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.04788
BRD-K12640996	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02541
outer CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63086
neuron projection	GO Cellular Component Annotations 2015	1.0	null
Mental Depression	DisGeNET Gene-Disease Associations	1.0	null
Breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
Pituitary gland tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.854
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5641-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MB-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN009_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.10568
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5459-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletal muscle cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060525
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.904957
Adenohypophysis tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.468
CRCGN014_HEPG2_24H:I19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.269
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6793-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SW156	DepMap CRISPR Gene Dependency	1.0	3.47544
cushing's syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.572662
epitiostanol-4204	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K51525251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03818
regulation of response to stimulus	GO Biological Process Annotations 2015	1.0	null
betahistine-6611	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54J-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of primary metabolic process	GO Biological Process Annotations 2015	1.0	null
[<sup>125</sup>I]Tyr<sup>10</sup>-CST14	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
GSE196699_4_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pituitary cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.916
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03007
r3 liminal central gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12743
BRD-K14258088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12313
Postsubiculum, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16868
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33696
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.197
SUCLG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65753
iopamidol-5832	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.970407
rofecoxib-256	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09144
AM-095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55813
sotos syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.681096
Golgi lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.696
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.69979
Paraganglioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.71
testis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.06686
icSARS CoV_7Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.75877
Puberty, Delayed	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K99522349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08935
Endometriosis	DisGeNET Gene-Disease Associations	1.0	null
CRCGN013_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.2099
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.849678
Diabetes	DisGeNET Gene-Disease Associations	1.0	null
BRD-K20068050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09452
Perturb_660_KD_lncRNA_166788_SRP093784	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.90102
Stomach	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.383
r5 (gustatory) part of solitary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30773
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE42805,GSE42811_2_v_3_cocaine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3251736__F2	PFOCR Pathway Figure Associations 2024	1.0	null
amygdaloid complex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.33796
fibroblasts	GeneRIF Biological Term Annotations	1.0	null
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954214
CRCGN014_HEPG2_3H:L18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23694
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21811
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A5BI-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
negative regulation of nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
respectively	GeneRIF Biological Term Annotations	1.0	null
abnormal respiratory function	MPO Gene-Phenotype Associations	1.0	null
variable	GeneRIF Biological Term Annotations	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
gramine-3999	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cell projection part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04682
Antropyloric mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.71
Leukemia	DisGeNET Gene-Disease Associations	1.0	null
Hereditary Hemochromatosis	DisGeNET Gene-Disease Associations	1.0	null
Meningeal Melanoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K33956247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11056
Prostate adenocarcinoma_PRAD_TCGA-G9-7519-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMRT-22465074-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CEBPD	ChEA Transcription Factor Targets	1.0	null
cellular response to peptide hormone stimulus	GO Biological Process Annotations 2015	1.0	null
BRD-K45428339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52091
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27047
Hypercholesterolemia	DisGeNET Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.0203
Cholestasis	DisGeNET Gene-Disease Associations	1.0	null
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58535
Childhood Leukemia	DisGeNET Gene-Disease Associations	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
Mucosal mast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.857
Acth-Independent Macronodular Adrenal Hyperplasia	DisGeNET Gene-Disease Associations	1.0	null
VMRCLCD	CCLE Cell Line Gene CNV Profiles	1.0	1.75774
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Ocular Albinism	DisGeNET Gene-Disease Associations	1.0	null
Gallbladder disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A57M-01A-51R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.663342
CRCGN015_HEPG2_48H:M17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.92505
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
D-54MG cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
PANC0813	CCLE Cell Line Gene CNV Profiles	-1.0	-1.76404
Differentiated thyroid gland carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10788
Polyps	DisGeNET Gene-Phenotype Associations	1.0	null
HES2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0648
BRD-K36120694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07799
CD4+_Tcells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.15181
cingulate cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01906
NNC269100	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
BRD-K82883803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71581
OSRC2	CCLE Cell Line Gene CNV Profiles	1.0	1.4342
PMC10082806-42003_2023_4756_MOESM4_ESM.xlsx-AML2_RelvsTum_DMRs_anno-annot_symbol_RUNX3	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN015_HEPG2_48H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12449
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.868432
Neuroepithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.64922
RPL22L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77984
neuropeptide signaling pathway	GO Biological Process Annotations 2015	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37991633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21156
Somatostatinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.688
CRCGN016_MCF10A.WT.HP_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.94773
Field CA2, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11889
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KE 108	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K53326976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.78129
PMC7938710__F3	PFOCR Pathway Figure Associations 2023	1.0	null
g-protein coupled peptide receptor activity	GO Molecular Function Annotations 2015	1.0	null
Adult Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
SNU1076	CCLE Cell Line Gene CNV Profiles	1.0	2.19438
CRCGN016_MCF10A.TP53.M_24H:O18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.42881
Childhood Glioblastoma	DisGeNET Gene-Disease Associations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3359-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Non-Convulsive Status Epilepticus	DisGeNET Gene-Disease Associations	1.0	null
short insular gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26479
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00623
Rheumatoid Arthritis	DisGeNET Gene-Disease Associations	1.0	null
Adrenal Cushing'S Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Corticotropic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.43
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5434-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Primary Pigmented Nodular Adrenocortical Disease	DisGeNET Gene-Disease Associations	1.0	null
AR4-2J cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.644
increased susceptibility to type iv hypersensitivity reaction	MPO Gene-Phenotype Associations	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5887-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-1.98782
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.819412
Von Willebrand Disease	DisGeNET Gene-Disease Associations	1.0	null
CRCGN015_HEPG2_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.48719
intermediate stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57558
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06403738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25571
BRD-K17062413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34638
RXF393	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.867222
Prostate adenocarcinoma_PRAD_TCGA-HC-8262-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.27381
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormal pain threshold	MPO Gene-Phenotype Associations	1.0	null
sublayer 6a of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04258
Pons	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.17695
RBM43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28695
CTCF_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66649343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.573
RUNX1_KO_GDS1511_250_mouse_Embryos at E8.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K94506829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20401
Postcentral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.051
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.2883
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.937903
Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Paraventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.044
posterior orbital gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00436
negative regulation of nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
Depression	DisGeNET Gene-Disease Associations	1.0	null
BIM 23068	DGIdb Drug Targets 2026	1.0	0.504114
Adenocarcinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K46603043	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0719
BRD-K25718133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05446
Fatty Liver	CTD Gene-Disease Associations	1.0	1.22048
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.128278
Small cell lung cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
abnormal hematopoietic system morphology/development	MPO Gene-Phenotype Associations	1.0	null
BRD-K09960817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60634
response to lipid	GO Biological Process Annotations 2015	1.0	null
dexibuprofen-6471	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Dorsal raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.103506
LUTETIUM OXODOTREOTIDE LU-177	DGIdb Drug Targets 2026	1.0	0.907406
hormone-mediated signaling pathway	GO Biological Process Annotations 2015	1.0	null
BRD-K04695511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10823
Thyroid adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
8305C	CCLE Cell Line Gene CNV Profiles	1.0	1.3929
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0353
EED-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.69945
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.95616
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.13944
somatostatin receptor activity	GO Molecular Function Annotations 2025	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4722-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.904351
Retrosplenial area, lateral agranular part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07598
Petit Mal Status	DisGeNET Gene-Disease Associations	1.0	null
tubocurarine chloride-5449	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
r3 pontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33358
Psammomatous meningioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
regulation of intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.208671
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10248
SMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1784
spaglumic acid-2962	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cellular response to lipid	GO Biological Process Annotations 2015	1.0	null
hypermethylation	GeneRIF Biological Term Annotations	1.0	null
hek-293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.416195
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07763
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K18494310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01343
Hirschsprung Disease	DisGeNET Gene-Disease Associations	1.0	null
CRCGN009_HEPG2_24H:F19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.44035
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC8569982-41065_2021_205_MOESM1_ESM.xlsx-mono_THP1_a2b_tpm1-gene_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-8454-11A-01R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6329-01A-13R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.685
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.937422
memantine-2934	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
heterodimerization	GeneRIF Biological Term Annotations	1.0	null
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.738442
MRPL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18341
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Noc complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.959
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5671-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dorsomedial nucleus of the hypothalamus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21257
CRCGN015_HEPG2_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.04487
medial part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29813
positive regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
CEBPD-23245923-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CEBPA-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.95314
SKUT1	DepMap CRISPR Gene Dependency	1.0	2.93679
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955717
Prelimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18253
pulmonary edema	MPO Gene-Phenotype Associations	1.0	null
CRCGN014_HEPG2_3H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5822
BRD-K39584933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4745
CRCGN012_HEPG2_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05938
liminal part of the r9 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0285
Malignant Pleural Mesothelioma	DisGeNET Gene-Disease Associations	1.0	null
dydrogesterone-2811	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GRIPAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53713
KYO1	DepMap CRISPR Gene Dependency	1.0	2.06426
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r2 part of prepontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39989
Liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
ChIP_SUZ12_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TJAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14099
Infection By Babesia Bovis	DisGeNET Gene-Disease Associations	1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13528
DPP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12565
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE196699_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1869	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49076
subiculum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.543359
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.691
tetraethylenepentamine-574	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Acute Lung Injury_Whole blood_GSE10474	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.18681
Secondary motor area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12333
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31905
RPMI 8226	BioGPS Cell Line Gene Expression Profiles	1.0	0.848554
MEL270	DepMap CRISPR Gene Dependency	1.0	3.77957
BRD-K87277021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13444
cytoplasm	GeneRIF Biological Term Annotations	1.0	null
molecular layer of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36027
KURAMOCHI	DepMap CRISPR Gene Dependency	1.0	3.16785
Gastrointestinal system benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.812
positive regulation of phosphorylation	GO Biological Process Annotations 2015	1.0	null
BRD-K82539366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42407
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.11899
ANALOG 32 [PMID:18543899]	DGIdb Drug Targets 2026	1.0	0.756171
GPR160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82315
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.87998
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TE-11	GDSC Cell Line Gene Expression Profiles	1.0	1.51179
Subiculum, dorsal part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20096
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.12789
neurotransmitter receptor activity	GO Molecular Function Annotations 2015	1.0	null
NCIH2030	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41991
cellular response to organonitrogen compound	GO Biological Process Annotations 2015	1.0	null
BRD-K32477623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07283
19074878-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
avian pallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.469987
GRK5	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5095-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cortico-medial group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15276
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69057
Primary visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14301
tioguanine-642	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
betonicine-4301	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HIC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5802
Lung adenocarcinoma_LUAD_TCGA-91-6831-11A-02R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRPS1_Mutation_GDS4493_594_mouse_Whisker pads	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Bartter Disease	DisGeNET Gene-Disease Associations	1.0	null
&beta;<sup>3</sup>-tetrapeptide	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
Subiculum, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10424
nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.185016
Field CA2, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48365
Checkpoint clamp complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.721
abnormal interferon secretion	MPO Gene-Phenotype Associations	1.0	null
adrenal cortex disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.478668
IRF6_KO_GDS2359_126_mouse_skin E17.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K83466873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25579
Mitochondrial DNA copy number	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.822185
Hypothermia	CTD Gene-Disease Associations	1.0	1.18652
pituitary	GeneRIF Biological Term Annotations	1.0	null
BRD-K71716722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14257
OMM25	DepMap CRISPR Gene Dependency	1.0	2.41081
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28312
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.37075
CRCGN017_MCF10A.TP53.M_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.5925
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19645
Urothelial carcinoma_Urothelium_GSE3167	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.58861
premalignant	GeneRIF Biological Term Annotations	1.0	null
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5FP-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thyroid gland adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049564
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21986
cerebellar cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.144328
Major depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
JURKAT	BioGPS Cell Line Gene Expression Profiles	1.0	0.848554
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.85542
receptor activity	GO Molecular Function Annotations 2015	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pituitary gland benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.44
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.25
abnormal inflammatory response	MPO Gene-Phenotype Associations	1.0	null
r6 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10553
CRCGN008_HEPG2_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1333
Lung adenocarcinoma_LUAD_TCGA-91-6836-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3908_KD_ALDH1A1_SRP164778	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.88816
PMC4467679-12967_2015_546_MOESM3_ESM.csv--TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
G alpha (i) signalling events	Reactome Pathways 2014	1.0	null
COLO684	CCLE Cell Line Gene Expression Profiles	1.0	1.9607
Pituitary adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.441
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55671
BRD-K75887263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07615
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
ML1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.00826
perphenazine-1540	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
placenta	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.29097
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5222
BRD-K37971917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44404
BRD-K32522318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64626
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7995
r7 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45178
BRD-K29200961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01046
LHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84531
MKN28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
monensin-3704	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4289
ETV4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7805
Lung squamous cell carcinoma_LUSC_TCGA-85-8049-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4622-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer SZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21043
SUIT2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53595
BRD-K38035271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13957
prostate cancer	GAD Gene-Disease Associations	1.0	null
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.28559
Familial Benign Hypercalcemia	DisGeNET Gene-Disease Associations	1.0	null
Autosomal Dominant Retinitis Pigmentosa	DisGeNET Gene-Disease Associations	1.0	null
CRCGN011_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5791
parasitic helminthiasis infectious disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055743
thyroid gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.514136
BRD-K83708664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11092
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4988-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82145108	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12402
BRD-K52731672	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2237
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85J-01A-12R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-01A-01R-1193-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gonadotrophic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.53
Brain Lower Grade Glioma_LGG_TCGA-DU-5851-01A-13R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ischemic Stroke	DisGeNET Gene-Disease Associations	1.0	null
Dopaminergic A13 group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13035
follicular thyroid carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.496557
reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.319363
OVCAR3	BioGPS Cell Line Gene Expression Profiles	1.0	0.848554
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.1129
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046339
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10207
demecarium bromide-5795	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K34136030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07662
BRD-K85659077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39495
oxoacid metabolic process	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
further	GeneRIF Biological Term Annotations	1.0	null
shell of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06668
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
Pseudohypoparathyroidism	DisGeNET Gene-Disease Associations	1.0	null
thyroid cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.613183
small intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.387781
abnormal adaptive immunity	MPO Gene-Phenotype Associations	1.0	null
BTF3L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20399
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28759
Endocrine system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.039
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SW1417	CCLE Cell Line Gene CNV Profiles	1.0	1.85359
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6097-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal neutrophil physiology	MGI Mouse Phenotype Associations 2023	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954214
MCC13	DepMap CRISPR Gene Dependency	1.0	2.93869
SOX2-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K47261271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11684
BRD-K78347804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04041
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4072
GSE126345_0_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4801-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SMC1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
pancreatic cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.138018
Dorsal premammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52109
BRD-A14331394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21578
AN3-CA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KE 108	DGIdb Drug Targets 2026	1.0	0.302469
CAL-51	GDSC Cell Line Gene Expression Profiles	-1.0	-1.71785
CRCGN015_HEPG2_48H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7109
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	92.7767
CRCGN015_HEPG2_48H:M08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23896
CALU3	CCLE Cell Line Gene CNV Profiles	-1.0	-2.42789
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.62121
response to steroid hormone	GO Biological Process Annotations 2015	1.0	null
r10 part of vagal motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73486
clozapine-5589	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36434
PRC1_BMI_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
BRD-K99564685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61558
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.5468
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LCAM1	DepMap CRISPR Gene Dependency	1.0	3.62563
BRD-K20799008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28262
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.35409
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
adrenal gland hyperfunction	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.511112
Mental Disorders	HuGE Navigator Gene-Phenotype Associations	1.0	null
EFM192A	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64591
ventromedial hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260606
Fibrous Dysplasia	DisGeNET Gene-Disease Associations	1.0	null
flunisolide-3923	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41569
sirolimus-5602	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Thrombophilia	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K17420784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33325
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.85326
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.971171
abnormal fluid regulation	MPO Gene-Phenotype Associations	1.0	null
cellular response to glucocorticoid stimulus	GO Biological Process Annotations 2023	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17115
Thyroid Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.29391
NCIH650	DepMap CRISPR Gene Dependency	1.0	2.22234
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.146
H-C[DCYS-PHE-LAGL(N&BETA;ME,BENZOYL)-DTRP-LYS-THR-PHE-CYS]-OH	DGIdb Drug Targets 2026	1.0	1.51234
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4337-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HEC6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36184
LU-134-A	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51056
Pyloric cecum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.078
CRCGN012_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.44379
ARNT-22903824-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43045
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
levobunolol-4016	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Barrington's nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03429
CRCGN017_MCF10A.TP53.M_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.09231
BRD-K52634604	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82616
AHR	ChEA Transcription Factor Targets	1.0	null
metacycline-4062	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20415826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35146
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35345
UACC-62	GDSC Cell Line Gene Expression Profiles	-1.0	-2.07571
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9047
BRD-K96054771	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.50225
Acute Myeloid Leukemia_LAML_TCGA-AB-2823-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K68836091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35808
Von Hippel-Lindau disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
CRCGN010_HEPG2_24H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.024
gh3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.657866
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
NCI-H64	COSMIC Cell Line Gene Mutation Profiles	1.0	null
bone marrow cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.158113
Primary motor area, Layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04526
BRD-K96778009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21679
vitelline membrane	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.613764
midbrain reticular formation, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.830488
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08345
BXPC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.94033
layer 6 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18825
hippocampus (hippocampal formation)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.28761
Adult Medulloblastoma	DisGeNET Gene-Disease Associations	1.0	null
estradiol-1633	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2693-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARG-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HCC4006	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04628
peripheral neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.120846
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A704	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44502
ChIP_TRIM28_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5106-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168076,GSE168080_1_v_0_batf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Zollinger-Ellison syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.466
sstr4mediated	GeneRIF Biological Term Annotations	1.0	null
abnormal interleukin-1 secretion	MPO Gene-Phenotype Associations	1.0	null
PMC7005888-41598_2020_58845_MOESM2_ESM.xlsx-Insulinoma-INSM1_INSM1	Rummagene Transcription Factor Associations 2026	1.0	null
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32987
anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06883
splitomicin-661	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Breast Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
Insulinoma	DisGeNET Gene-Disease Associations	1.0	null
BRD-K64353626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49873
nefopam-3627	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:A21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.08805
sulconazole-3035	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IK-01A-32R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pituitary gland tumor cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.828616
LTBR_INHIBITION - 3 Day_GDS2004_735_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CRCGN014_HEPG2_3H:J22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6712
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-DX-A7EI-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Peptide GPCRs(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
cartilage	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057951
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
studied	GeneRIF Biological Term Annotations	1.0	null
CRCGN011_HEPG2_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.94605
REST	ENCODE Transcription Factor Targets	1.0	null
LLC-WRC 256 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.581
BIM 23295	DGIdb Drug Targets 2026	1.0	1.51234
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
diabetic	GeneRIF Biological Term Annotations	1.0	null
GSE196699_7_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
prostate gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.533856
BRD-K52956006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24039
GSE196699_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Becker	GDSC Cell Line Gene Expression Profiles	-1.0	-1.66755
somatotrophinomas	GeneRIF Biological Term Annotations	1.0	null
BRD-K64137284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70366
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K05261060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67698
medial geniculate nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23761
CRCGN008_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.6436
CRCGN017_MCF10A.WT.HP_24H:E10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.8724
Appendix	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05295
r7 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04971
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC10916124-12864_2024_10174_MOESM1_ESM.xlsx-Supplementary_Table_6-The_downstream_genes_targeted_by_FLI1_The_ligand_vs_receptor_pairs_genes_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
DOK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.959446
EED-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.695
EED	ChEA Transcription Factor Targets	1.0	null
BRD-K40419401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02854
BRD-K46014233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03798
abnormal immune system morphology	MPO Gene-Phenotype Associations	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.45191
Non-odorant GPCRs(Mus musculus)	WikiPathways Pathways 2014	1.0	null
PPARG-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Hepatic artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.733
CCNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04909
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.895261
BRD-K73780763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8054
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.17115
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.265677
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.020991
Pancreatic endocrine carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.331
KHM1B	CCLE Cell Line Gene Expression Profiles	1.0	1.69189
BRD-K39709957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05377
paroxetine-3821	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K04786080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27518
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.263327
BRD-K93126086	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85546
PMC4050971__F3	PFOCR Pathway Figure Associations 2024	1.0	null
CRCGN015_HEPG2_48H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12975
UOK101	CCLE Cell Line Gene Expression Profiles	1.0	1.47243
ventrolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25502
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Postural Orthostatic Tachycardia Syndrome	DisGeNET Gene-Disease Associations	1.0	null
pontine raphe nucleus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.53693
ATN-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01544
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.867272
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.881086
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anxiety	DisGeNET Gene-Phenotype Associations	1.0	null
Infralimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43383
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.86349
gracile nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.97492
BRD-K86721033	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66368
NCIH929	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70434
BRD-K96076719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63694
receptors	GeneRIF Biological Term Annotations	1.0	null
BRD-K94789179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41079
spinal trigeminal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11096
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043831
Ileal carcinoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.102
therapy	GeneRIF Biological Term Annotations	1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.64529
CRCGN015_HEPG2_48H:J17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.18614
layer 5 of OCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0073
Neuralgia	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K08489825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3899
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
secretory	GeneRIF Biological Term Annotations	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955717
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
BRD-K79816111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31466
PSMG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8688
CRCGN015_HEPG2_48H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	7.38309
Heart Failure	DisGeNET Gene-Disease Associations	1.0	null
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5106
Cystic Fibrosis	DisGeNET Gene-Disease Associations	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K88658905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41034
Intestinal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
PNU-0230031-3732	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K85972696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34609
SALL4	ChEA Transcription Factor Targets	1.0	null
CRCGN013_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.41059
A549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955717
monorden-449	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.960556
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.72248
Benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.151
orciprenaline-4248	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF460	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81345
posterior tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36428
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	1.13867
xylometazoline-1423	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GRK7	Pathway Commons Protein-Protein Interactions	1.0	null
homeostasis/metabolism phenotype	MPO Gene-Phenotype Associations	1.0	null
shows	GeneRIF Biological Term Annotations	1.0	null
ChIP_RNF2_22325148	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Diethylnitrosamine	CTD Gene-Chemical Interactions	1.0	null
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
17683608-TableS1	GeneSigDB Published Gene Signatures	1.0	null
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN012_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.917
PMC7021771-41467_2020_14684_MOESM8_ESM.xlsx-CASZ1_specific_peaks-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
removed	GeneRIF Biological Term Annotations	1.0	null
BRD-K21546432	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12207
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.433
SH3GLB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69872
32D cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.823
deregulated	GeneRIF Biological Term Annotations	1.0	null
Bladder	GTEx Tissue Gene Expression Profiles 2023	1.0	2.95274
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04353
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
496100622_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.22152
Respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
STAT5A-24692510-EPITHELIUM-MOUSE-MAMMARY	ChEA Transcription Factor Targets 2022	1.0	null
quercetin-283	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90521
pronephros	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33744
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.236332
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069319
BRD-K44946060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12668
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86605
SUZ12-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZNF415	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93936
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.22566
exocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.079232
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-93-A4JN-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Subiculum, dorsal part, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50847
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.28097
KATNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04548
GSE210885_2_v_6_klf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
several psychiatric disorders	GAD Gene-Disease Associations	1.0	null
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SALL4-18804426-XEN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
thyroid adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.60069
Acute Erythroblastic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
internal female genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
CRCGN016_MCF10A.WT.HP_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.91494
BHMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27678
BRD-A76905089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09146
BRD-K75724196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3109
Field CA1, stratum oriens	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75452
NCI-H358	COSMIC Cell Line Gene Mutation Profiles	1.0	null
secondary oocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.351856
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.12183
23132-87	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K07414059	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.40937
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.865577
MOLT4	BioGPS Cell Line Gene Expression Profiles	1.0	1.53291
TGBC24TKB	GDSC Cell Line Gene Expression Profiles	1.0	1.95276
Extrinsic component of cytoplasmic side of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.118
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.7437
single-organism developmental process	GO Biological Process Annotations 2015	1.0	null
BRD-A20213616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10367
Avian pallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.539
Dermatitis	DisGeNET Gene-Disease Associations	1.0	null
negative regulation of purine nucleotide metabolic process	GO Biological Process Annotations 2015	1.0	null
meningioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.248361
SUM190PT	DepMap CRISPR Gene Dependency	1.0	2.76724
NR2C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.0016
liothyronine-2984	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SUZ12-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Breast disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.28
CRCGN015_MCF10A_48H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.36198
GSE157592_1_v_0_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intestine	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.447192
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.63294
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
uterus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.096455
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
neuron part	GO Cellular Component Annotations 2015	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.442962
tiletamine-6013	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K88447092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.408
ChIP_RNF2_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Down Syndrome	DisGeNET Gene-Disease Associations	1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.961528
Perturb_11761_KO_Arg2_SRP198795	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.64811
KLF4-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K60107240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06241
Muscular coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.5
HCC1897	CCLE Cell Line Gene Expression Profiles	1.0	2.14984
GRK4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K05339908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05602
Median eminence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.944
sstr3	GeneRIF Biological Term Annotations	1.0	null
Tumor Angiogenesis	DisGeNET Gene-Phenotype Associations	1.0	null
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.719113
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
sensory peripheral neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.243995
r9 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01097
BRD-K70565285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05729
BRD-K59701963	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37374
BRD-K18726958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46642
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
BRD-K57404319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15512
sitosterol-4073	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Neuroendocrine tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.809
ChIP_EED_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K06896230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86717
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VELDOREOTIDE	DGIdb Drug Targets 2026	1.0	0.756171
superior frontal gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.65435
Stomach smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
HELA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.25434
PCDH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01604
SUDHL8	CCLE Cell Line Gene Expression Profiles	1.0	1.48789
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-8312-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:J10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.7796
pet	GeneRIF Biological Term Annotations	1.0	null
single organism signaling	GO Biological Process Annotations 2015	1.0	null
smooth muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.303559
BRD-K47694606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21937
embryonic cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.227186
CORT	Guide to Pharmacology Protein Ligands of Receptors	1.0	null
Functioning pituitary adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.249
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TC-71	COSMIC Cell Line Gene Mutation Profiles	1.0	null
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
SMAD3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.28
germ cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.135552
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.37995
shell of T-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23461
CRCGN013_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7923
GATA3-21867929-CD8-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01309
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.60386
adult stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066069
cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.28816
Vitamin D levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.839794
dorsomedial nucleus, terminal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23684
BRD-K22062326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13661
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A953-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
oculomotor nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32742
alterations	GeneRIF Biological Term Annotations	1.0	null
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
dimethyloxalylglycine-584	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Gill arch	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
inferolateral temporal cortex (area TEv, area 20)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.966291
ZNF263	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A430-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8010-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.897942
Brain Lower Grade Glioma_LGG_TCGA-HT-7856-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Attention Deficit Disorder	DisGeNET Gene-Disease Associations	1.0	null
CRCGN017_MCF10A.WT.HP_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.05755
BRD-K93956318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14798
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07192
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
Thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.913
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Neuroblastoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.193
Nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
Carcinoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.866
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPD-21427703-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ELAVL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97737
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K96154586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7828
germ cell cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.510728
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GX-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCCMPNST1C1	DepMap CRISPR Gene Dependency	1.0	3.36018
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28495
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.1245
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.20778
BRD-K99131664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10122
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01707
BRD-K64692525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56594
Pheochromocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.818
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.907503
Class A/1 (Rhodopsin-like receptors)	Reactome Pathways 2014	1.0	null
NCI-H520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.11814
PMC10933475-41420_2024_1892_MOESM1_ESM.pdf-1-EGR4_EGR4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Enteropathy-Associated T-Cell Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3012
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.339
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37775
r8 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50003
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
CONSOMATIN FJ1	DGIdb Drug Targets 2026	1.0	1.51234
signaling	GO Biological Process Annotations 2015	1.0	null
abnormal respiratory system physiology	MPO Gene-Phenotype Associations	1.0	null
Rickets	DisGeNET Gene-Disease Associations	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Calculi	DisGeNET Gene-Disease Associations	1.0	null
BRD-K61050695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41636
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.963
RNF122	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01127
XPC complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.71
RNF2-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
dermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.147685
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
ADRBK2	Pathway Commons Protein-Protein Interactions	1.0	null
C-fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.914
BRD-K15280583	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18421
BRD-A54490075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48506
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adult Acute Lymphocytic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
pyramidal layer of S	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34334
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45247
tissue	GeneRIF Biological Term Annotations	1.0	null
GATA2	ENCODE Transcription Factor Targets	1.0	null
GSE198380_0_v_1_phgdh_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
transcripts	GeneRIF Biological Term Annotations	1.0	null
MM160113	DepMap CRISPR Gene Dependency	1.0	10.121
increased interferon-gamma secretion	MGI Mouse Phenotype Associations 2023	1.0	null
brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.166591
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.458
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.42038
sst	GeneRIF Biological Term Annotations	1.0	null
Multiple endocrine neoplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
Intracranial meningioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.115
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.17757
Prelimbic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.339
BRD-K33597325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15651
496100656_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.70117
Apical dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.028
copper sulfate-575	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
BRD-K79982586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73619
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4769-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
isthmic roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17655
BRD-K33734659	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19411
Rectum adenocarcinoma_READ_TCGA-AF-6655-01A-11R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
BRD-K82082713	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47492
NCIH2171	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69269
sulfaguanidine-4839	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K27543887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32607
cellular response to peptide	GO Biological Process Annotations 2015	1.0	null
abnormal interferon-gamma secretion	MPO Gene-Phenotype Associations	1.0	null
SKMEL3	CCLE Cell Line Gene CNV Profiles	1.0	1.45488
Kidney Chromophobe_KICH_TCGA-KL-8334-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH727	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58987
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.272
Primary motor area, Layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05937
KS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40448
amiprilose-4000	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.31584
Acute Lymphocytic Leukemia	DisGeNET Gene-Disease Associations	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.240148
sstr	GeneRIF Biological Term Annotations	1.0	null
sst1	GeneRIF Biological Term Annotations	1.0	null
Heartburn	DisGeNET Gene-Phenotype Associations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KK-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
changes	GeneRIF Biological Term Annotations	1.0	null
sirolimus-326	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.28951
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A51B-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.652
pancreatic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.488549
BRD-K12930517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17995
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K08607520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03561
HCC1569	CCLE Cell Line Gene CNV Profiles	1.0	1.40784
colonic cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064586
basis	GeneRIF Biological Term Annotations	1.0	null
periventricular stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1879
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30726
CRCGN012_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.64638
MTF2	ChEA Transcription Factor Targets	1.0	null
Fibrosis	CTD Gene-Disease Associations	1.0	1.13313
BRD-K63614330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26583
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
BRD-K00797068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.16076
ncih727	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.64
BRD-K64509887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37484
Intestinal T-Cell Lymphoma	DisGeNET Gene-Disease Associations	1.0	null
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
Heterotrimeric G-protein signaling pathway-Gq alpha and Go alpha mediated pathway	PANTHER Pathways	1.0	null
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33647
hippocampus (cortex Ammonis)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62485
BRD-K51448234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0967
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.11081
Lung adenocarcinoma_LUAD_TCGA-50-5931-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ketanserin-6649	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Colorectal cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
connective tissue cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049095
RT112	CCLE Cell Line Gene Expression Profiles	1.0	1.63065
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.0424
regulation of cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
mast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.124694
BRD-K92513859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25371
uterine endometrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.288158
GSE209911_0_v_1_ncstn_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney - Medulla	GTEx Tissue Gene Expression Profiles 2023	1.0	3.91997
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.052
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4771-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.41439
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.24933
embryonic kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.415053
BRD-K71184289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7903
REST	ChEA Transcription Factor Targets	1.0	null
metoclopramide-3625	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1563	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RARG-19884340-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
r10 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02172
[<sup>125</sup>I]Tyr<sup>11</sup>-SRIF-14	Guide to Pharmacology Chemical Ligands of Receptors	1.0	null
Midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.702
Rectum adenocarcinoma_READ_TCGA-AG-4021-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059638
Mammillary body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06008
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41658
HCC38	CCLE Cell Line Gene CNV Profiles	1.0	1.65376
CRCGN017_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6829
H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EFO-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11373
cellular response to steroid hormone stimulus	GO Biological Process Annotations 2015	1.0	null
CRCGN015_HEPG2_48H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.56673
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.851173
somatostatin signaling pathway	GO Biological Process Annotations 2015	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6982-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IQ-01A-31R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6778-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHUEM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72649
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN016_MCF10A.TP53.M_24H:O21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43008
Lung adenocarcinoma_LUAD_TCGA-44-6144-11A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	149.487
NIPSNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96275
mast cells	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.0607
dorsal peduncular cortex, periventricular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04165
Eye	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.4
NANOG-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
increased tumor necrosis factor secretion	MPO Gene-Phenotype Associations	1.0	null
CRCGN015_HEPG2_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.94103
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.216