association	dataset	threshold value	standardized value
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.895403
ABCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90837
SARS-ddORF6_60Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.45592
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fibroblast cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062089
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.31628
SERPINH1	Pathway Commons Protein-Protein Interactions	1.0	null
496100589_PCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53801
septopallidal core nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18396
hsa-miR-302d	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
ficolin-1-rich granule membrane	GO Cellular Component Annotations 2023	1.0	null
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33633
EEF1G	Pathway Commons Protein-Protein Interactions	1.0	null
Anemia	CTD Gene-Disease Associations	1.0	1.29164
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
VSIG8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE149035_2_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
khellin-4987	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
STRBP	Pathway Commons Protein-Protein Interactions	1.0	null
FLI1-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
GSE169697,GSE169725_1_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HSPB1	Pathway Commons Protein-Protein Interactions	1.0	null
OVTOKO	DepMap CRISPR Gene Dependency	1.0	5.001
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78728
Vision Disorders	CTD Gene-Disease Associations	1.0	1.22016
RCC2	Pathway Commons Protein-Protein Interactions	1.0	null
lateral medullary reticular group, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12373
laterorostral part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24581
PRSS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03675
DKC1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5988-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
pyrantel-5088	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_HEPG2_48H:A09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04286
TRIAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11321
Perturb_154_KD_Tmbim1_SRP319128	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE126463_6_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ACAT1	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CNN3	Pathway Commons Protein-Protein Interactions	1.0	null
Glycogen metabolism disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.209
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-K1-A6RT-01A-32R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ethosuximide-7308	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE233679_5_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7355
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40558
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.684242
DNAJB1	Pathway Commons Protein-Protein Interactions	1.0	null
aconitine-2776	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.847062
FAM91A1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Carbohydrate-binding-like fold	InterPro Predicted Protein Domain Annotations	1.0	null
GSE248858_4_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OTX2_KO_GSE27630_51_mouse_brain (fourth ventricular choroid plexus, E13)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN015_MCF10A.WT.HP_24H:A18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.78085
hsa-miR-4789-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7887-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
spiramycin-2558	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Claw	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149264,GSE149267_9_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1793	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.83088
GSE174498,GSE174500_3_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y0-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NME1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.617
PPIA	Pathway Commons Protein-Protein Interactions	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.57041
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PHF21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00063
GSE244730_0_v_1_erlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05929
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5404927-elife-24463-supp1.xlsx-1b_ERM_proteome-Gene_names_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
ACTN1	Pathway Commons Protein-Protein Interactions	1.0	null
KMS27	CCLE Cell Line Gene Expression Profiles	1.0	1.40075
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KRT24	Pathway Commons Protein-Protein Interactions	1.0	null
Lung Neoplasms	CTD Gene-Disease Associations	1.0	1.50423
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
chr4_76297904_G_T_b38	GTEx eQTL 2025	1.0	4.56749
BCL7C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26836
ACTA2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_6_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE81803,GSE81912_3_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.893627
SR-786	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02577
ARID3A	ENCODE Transcription Factor Targets	1.0	null
plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.129757
LGALS7B	Pathway Commons Protein-Protein Interactions	1.0	null
PPARGC1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18792
H3K9ac_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Supplemental somatosensory area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22045
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GORAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04719
Perturb_130_KD_Tcf7l2_SRP100171	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.09835
CMBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2474
MFE296	CCLE Cell Line Gene Expression Profiles	1.0	1.41226
MHH-ES-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF4A1	Pathway Commons Protein-Protein Interactions	1.0	null
dobutamine-6286	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.962858
S100A16	Pathway Commons Protein-Protein Interactions	1.0	null
IX, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.65786
GSE162892_3_v_2_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3917
IMPDH2	Pathway Commons Protein-Protein Interactions	1.0	null
Lafora disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.325
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
iopamidol-5832	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.871753
membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044193
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20923
etacrynic acid-5742	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32939
RPN1	Pathway Commons Protein-Protein Interactions	1.0	null
PHA-00846566E-7086	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Massive Hepatic Necrosis	CTD Gene-Disease Associations	1.0	1.26359
CRCGN017_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15255
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:I13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4093
MDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12962
TGM1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-4679-01B-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.93986
Thymus-vascular associated smooth muscle cell	Tabula Sapiens Gene-Cell Associations	1.0	3.79282
GSE229973_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FTC238	CCLE Cell Line Gene CNV Profiles	-1.0	-1.98225
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EPDR1	Pathway Commons Protein-Protein Interactions	1.0	null
ACTB	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-17	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBBP1A	Pathway Commons Protein-Protein Interactions	1.0	null
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91914
KHDRBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24514
IRF2BPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12163
Lung squamous cell carcinoma_LUSC_TCGA-77-8008-11A-01R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053323
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.995984
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE168797_2_v_3_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATG16L1	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3380-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-20b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE48812_11_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81J-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
buflomedil-1338	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
streptozocin-2535	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19C-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE154767_1_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DM-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.59891
ficolin-1-rich granule membrane	GO Cellular Component Annotations 2025	1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_iPS-20b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CJUN-26792858-CHIP-SEQ-BT549-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
anterior paraventricular nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25995
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Thrombocytopenia	CTD Gene-Disease Associations	1.0	1.06808
PRPF19	Pathway Commons Protein-Protein Interactions	1.0	null
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.963947
PIK3CG	Pathway Commons Protein-Protein Interactions	1.0	null
GSE205021_3_v_2_fenofibrate_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SERBP1	Pathway Commons Protein-Protein Interactions	1.0	null
CTSF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94953
superficial stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13132
srf_17591768_igmpos_igdpos_b_cells_lof_mouse_gpl339_gds2805	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.066816
GSE140322_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE167324_2_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KRT1	Pathway Commons Protein-Protein Interactions	1.0	null
GYS2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33028
Gaucher's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.24
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.840531
GART	Pathway Commons Protein-Protein Interactions	1.0	null
genistein-1015	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Adenoma, Liver Cell	CTD Gene-Disease Associations	1.0	1.38355
APLP2_KO_GDS4414_371_mouse_prefrontal cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HNRNPL	Pathway Commons Protein-Protein Interactions	1.0	null
STIP1	Pathway Commons Protein-Protein Interactions	1.0	null
UMUC16	DepMap CRISPR Gene Dependency	1.0	4.05931
Brain Lower Grade Glioma_LGG_TCGA-QH-A6CX-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dexpropranolol-5814	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RABGAP1	Pathway Commons Protein-Protein Interactions	1.0	null
sulfaphenazole-1794	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
XRN2	Pathway Commons Protein-Protein Interactions	1.0	null
Signal Transduction	Reactome Pathways 2024	1.0	null
BB65-RCC	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.20704
HSPA8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE169205_0_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TRAPPC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01555
496100639_TCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1149
EPPK1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE255432_7_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
post-lysosomal vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.515
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Parkinsonism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
LC1SQ	DepMap CRISPR Gene Dependency	1.0	2.08955
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3PL-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
F5	DepMap CRISPR Gene Dependency	1.0	2.17115
(+)-chelidonine-2779	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIKFYVE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18713
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
oxolinic acid-2103	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE252988_0_v_1_lefamulin_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100530_FWM_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19034
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RARA_01_51	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61592
Kidney - Cortex	GTEx Tissue Gene Expression Profiles 2023	1.0	1.22234
DCD	Pathway Commons Protein-Protein Interactions	1.0	null
Hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
WIPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53351
flumequine-5529	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.69925
SLC22A23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67142
Memory Disorders	CTD Gene-Disease Associations	1.0	1.71565
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAFF	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.75026
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Generalized Glycogen Storage Disease Of Infants	DisGeNET Gene-Disease Associations	1.0	null
Perturb_142_OE_Tmbim1_SRP319088	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
VMCUB1	CCLE Cell Line Gene CNV Profiles	1.0	2.28225
Pain	CTD Gene-Disease Associations	1.0	1.14575
r6 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19937
HSP90AA2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNRNPM	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_16592_KO_Trp53/Brca1_SRP186281	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.10505
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09609
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.058362
Medial preoptic nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99555
Postoperative Complications	CTD Gene-Disease Associations	1.0	1.2336
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QH-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A673_BONE	CCLE Cell Line Proteomics	1.0	3.07114
superficial stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.66074
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.97263
ACTBL2	Pathway Commons Protein-Protein Interactions	1.0	null
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67784
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WDR11	Pathway Commons Protein-Protein Interactions	1.0	null
GSE211177,GSE211178_4_v_1_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trapidil-7475	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNRPG	Pathway Commons Protein-Protein Interactions	1.0	null
HADHB	Pathway Commons Protein-Protein Interactions	1.0	null
STK33_SKM	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
CHTOP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE125153_2_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ajmaline-7484	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
irf1_17409403_nih3t3_gof_mouse_gpl81_gds2752	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.91063
GSE140936,GSE140938_0_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.95538
YAE1D1	Pathway Commons Protein-Protein Interactions	1.0	null
ECD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5192
CMLT1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62407
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Perturb_14832_KD_Scr_SRP017110	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTPBP4	Pathway Commons Protein-Protein Interactions	1.0	null
RPS27L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83596
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.7755
TMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
trichostatin A-2084	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Parabrachial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.552
morantel-1798	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE248858_5_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29655
MDH2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_12742_KD_GOT1_SRP282058	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.47189
Perturb_8342_KD_NREP_SRP233376	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.86728
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
MAP1LC3B	Pathway Commons Protein-Protein Interactions	1.0	null
Primary somatosensory area, barrel field, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12773
LUC7L2	Pathway Commons Protein-Protein Interactions	1.0	null
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.585
Paragigantocellular reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05619
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.834229
SLC50A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70242
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.946112
GSE158502,GSE158506_3_v_0_fat1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
trichostatin A-4344	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Ventricular Dysfunction	CTD Gene-Disease Associations	1.0	1.11911
TAF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8405-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFA4	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.47287
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.7764
pirenzepine-5872	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
outer SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.983989
fulvestrant-1663	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
YWHAQ	Pathway Commons Protein-Protein Interactions	1.0	null
GSE255432_6_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_6698_KD_ALAL1_SRP214241	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.32218
Lung squamous cell carcinoma_LUSC_TCGA-43-6647-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.960619
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
isoetarine-5812	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE100316_3_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE107505_0_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.959593
POLR2E	Pathway Commons Protein-Protein Interactions	1.0	null
PRKDC	Pathway Commons Protein-Protein Interactions	1.0	null
probucol_mus musculus_gpl9526_gds3619	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE211128_7_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:H06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.031
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM28	Pathway Commons Protein-Protein Interactions	1.0	null
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.45427
GSE211177,GSE211178_4_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.512589
SK-MEL-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07002
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.838852
KKU213	DepMap CRISPR Gene Dependency	1.0	3.26831
Perturb_5943_KD_POLDIP3_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.0755
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041991
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.928798
sulfadoxine-7205	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PK-59	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12861
NCL	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_12853_OE_Nr2e1_SRP055859	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.3902
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13321
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10555
Autophagosome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.407
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054135
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.644
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-10_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05803
KRT17	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I1-06A-12R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPS23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15967
ARID3A	JASPAR Predicted Transcription Factor Targets	1.0	null
KRT6A	Pathway Commons Protein-Protein Interactions	1.0	null
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.87659
Andersen-Tawil syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.173
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.973876
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SHP-77	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN010_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37719
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GL-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19677
TAL1_01_217	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.58735
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
oxolamine-3006	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.995242
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Paraventricular nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17925
Parabrachial nucleus, medial division, medial medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.15724
CRCGN016_MCF10A.WT.HP_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44532
GSE205163,GSE205164_1_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE226259_0_v_1_scd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lipid storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
thiocolchicoside-5520	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Right_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.0675
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL10	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4763
NEDD4	Pathway Commons Protein-Protein Interactions	1.0	null
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP1A2	Pathway Commons Protein-Protein Interactions	1.0	null
RB1CC1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC12549544-mmc2.xlsx-AA_D1_VS_D7-Name_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
trifluoperazine-6341	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.61432
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNRNPAB	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_11110_KO_Tsc1_SRP303636	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.36845
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-L9-A444-01A-21R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP5C1	Pathway Commons Protein-Protein Interactions	1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
external segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13417
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33826
CCT8	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LP1	CCLE Cell Line Gene Expression Profiles	1.0	2.47401
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_598_OE_HOTAIR_SRP342161	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210580_5_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DOK7	Pathway Commons Protein-Protein Interactions	1.0	null
ECH1	Pathway Commons Protein-Protein Interactions	1.0	null
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30126
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-498	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Nucleus sagulum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1847
suxibuzone-5806	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61432
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34914
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
liothyronine-4947	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Type 2 diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.294
CRCGN015_MCF10A_48H:H23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01054
GSE188870,GSE188871_0_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
sulfacetamide-1859	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE201401_2_v_0_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9927941-jci-133-163612-s046.xlsx-Sheet1-Table_S12_PAX5_expression_correlates_p_0_05_with_expression_of_126_of_the_other_T2D_DEGs_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE156708_1_v_0_fbxo11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
496100522_PCx_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37936
HNRNPH3	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-3188	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
ZFP36_Deficiency_GDS2456_707_mouse_Fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Sarcoma_SARC_TCGA-K1-A3PN-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
selective autophagy	GO Biological Process Annotations 2023	1.0	null
GSE179031_3_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IA-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:L14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8448
Prestwick-1082-7027	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mantle zone of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12898
SPI1-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
KKU100	DepMap CRISPR Gene Dependency	1.0	2.90419
amoxicillin-6285	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7332
Perturb_11189_KO_Pdx1_SRP252480	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.39489
SNRNP200	Pathway Commons Protein-Protein Interactions	1.0	null
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.00591
Danon disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.179
GSE126463_5_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
KIT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37279
GSE203308_4_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146612_2_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RPS5	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.872535
CEBPB	ENCODE Transcription Factor Targets	1.0	null
pontine nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22011
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228727_2_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205163,GSE205164_1_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-2_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE154767_1_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63209
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.452
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_124_KD_Tcf7l2_SRP100171	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.30341
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16426
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34392
YY1	ENCODE Transcription Factor Targets	1.0	null
15897907-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
LoVo	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.25688
CLTC	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF5A	Pathway Commons Protein-Protein Interactions	1.0	null
IGF2BP1	Pathway Commons Protein-Protein Interactions	1.0	null
HSPE1	Pathway Commons Protein-Protein Interactions	1.0	null
Corpus amylaceum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.272
TUBB2A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE116810_5_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
15955831-Table5	GeneSigDB Published Gene Signatures	1.0	null
azacitidine-3348	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
fluorometholone-2509	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE161842_1_v_2_kdm6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213650_3_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160001,GSE160670_3_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05173
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RGS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25144
(-)-atenolol-3067	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PURA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE203308_6_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
L3.6pl cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.68
sulfacetamide-6349	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100318_PCx_probable Alzheimer's disease_TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.04006
biological_process	GO Biological Process Annotations 2015	1.0	null
FTO	Pathway Commons Protein-Protein Interactions	1.0	null
TUBB	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FAM124B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29935
procaine-6329	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05732
H4K20me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PPP2R2B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE126463_0_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Muscular Diseases	CTD Gene-Disease Associations	1.0	1.20719
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.844552
TTC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03158
Diurnally Regulated Genes with Circadian Orthologs(Homo sapiens)	WikiPathways Pathways 2014	1.0	null
PMC3371315-NIHMS350140-supplement-9.xls-MCF7-T47D-SK-453_Up_MCF7-T47D_x-Supplementary_Table_2_ER-positive_FOXA1_signature_Genes_increased_only_in_MCF7_and_T47D_cells_with_knockdown_of_FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
Prestwick-1083-6357	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.6221
GSE88819_11_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_OTX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
isthmic part of mesencephalic trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.54749
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.859115
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CCRF-CEM	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE138815,GSE138817_0_v_2_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13481
HNF4A	ENCODE Transcription Factor Targets	1.0	null
GSE120370_4_v_1_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE186654_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_7747_KD_CNOT1_SRP155278	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.98898
E2F1-26619117-HEPATOCYTES-MOUSE-LIVER	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-98-A53D-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CRKL	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AHNAK	Pathway Commons Protein-Protein Interactions	1.0	null
zardaverine-2926	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PDE10A_KO_GDS4542_291_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RPS3	Pathway Commons Protein-Protein Interactions	1.0	null
EEF2	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIMM50	Pathway Commons Protein-Protein Interactions	1.0	null
GSE180200,GSE180201_12_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4985-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chr4_76299874_A_AT_b38	GTEx eQTL 2025	1.0	1.60832
GSE244233_1_v_0_quercetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2524
Nutritional deficiency, NEC_Skeletal Myocyte_GSE1776	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.86572
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MM1S	CCLE Cell Line Gene Expression Profiles	1.0	1.52353
RBM4B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE240645_3_v_2_u90926_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-WK-A8XY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
S100A9	Pathway Commons Protein-Protein Interactions	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.88869
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tetrandrine-2520	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LMX1B_KO_GDS3320_57_mouse_embryonic (e11.5) proximal hindlimb bud tissues	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ERG	ChEA Transcription Factor Targets	1.0	null
HuH-7	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.28058
GSE149903_0_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21398
CSNK2B	Pathway Commons Protein-Protein Interactions	1.0	null
periventricular stratum of isLim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32632
cefalonium-2921	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HNF4alpha_KO_GDS1915_173_mouse_Small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE131161_1_v_0_rarres1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.94231
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Tertiary granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
lysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.365859
GSE258991_5_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
AMDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60518
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214823,GSE214824_5_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC366	CCLE Cell Line Gene CNV Profiles	1.0	1.3999
spaglumic acid-7465	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PGAM2	Pathway Commons Protein-Protein Interactions	1.0	null
dipivefrine-7124	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
trichostatin A-3566	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
uterine cervix	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CKB	Pathway Commons Protein-Protein Interactions	1.0	null
cholecalciferol_mus musculus_gpl339_gse18993	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_10296_Mut_Pkd1_SRP385932	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
Lysosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.606
NAP1L4	Pathway Commons Protein-Protein Interactions	1.0	null
pyrithyldione-2740	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE195559_0_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
moxisylyte-1846	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
PAX3_Knock-in_GDS3331_598_mouse_Palatal shelves (E14.5 embryos - palate)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
azacitidine-4010	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RPS17	Pathway Commons Protein-Protein Interactions	1.0	null
central part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29019
LP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962583
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A4-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AR-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ATF7IP	Pathway Commons Protein-Protein Interactions	1.0	null
SF3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41556
hydralazine-4746	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
rolipram-5330	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE96991,GSE97117_5_v_2_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
interacting	GeneRIF Biological Term Annotations	1.0	null
NIPSNAP1	Pathway Commons Protein-Protein Interactions	1.0	null
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01995
PDIA6	Pathway Commons Protein-Protein Interactions	1.0	null
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7165_KD_FTH1_SRP385887	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.90121
Superior olivary complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2542
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10X-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08969
ALDH2	Pathway Commons Protein-Protein Interactions	1.0	null
BCKDHA	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62817
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT-549	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.900995
HSPA4L	Pathway Commons Protein-Protein Interactions	1.0	null
TSR1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE157594_3_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
P4HB	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH196	CCLE Cell Line Gene Expression Profiles	1.0	1.53223
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847243
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.57026
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53227
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.44004
GSE237040_2_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VCAP	CCLE Cell Line Gene CNV Profiles	1.0	1.96114
GSE114690_2_v_3_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39385
Kidney Diseases	CTD Gene-Disease Associations	1.0	2.0087
Fever	CTD Gene-Disease Associations	1.0	1.35763
NOP2	Pathway Commons Protein-Protein Interactions	1.0	null
EZR	Pathway Commons Protein-Protein Interactions	1.0	null
CCBL2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Medullary reticular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44424
ELF1	ENCODE Transcription Factor Targets	1.0	null
PFN1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06216
Pseudopalisading cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
GSE164874_5_v_14_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPL26L1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE202434,GSE202438_3_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SFN	Pathway Commons Protein-Protein Interactions	1.0	null
IGF2BP3	Pathway Commons Protein-Protein Interactions	1.0	null
NR1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23413
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.887373
CRCGN016_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00455
TDRD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05047
UBTF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92773
GSE226316_0_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pentoxyverine-2623	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.70043
MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37274
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32331
18698033-tableS1-ESR1	GeneSigDB Published Gene Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EJ-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
reticular formation of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16972
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUM149PT	DepMap CRISPR Gene Dependency	1.0	3.79932
PHYHIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67398
NHLRC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57792
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R7-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548i	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69838
Lung adenocarcinoma_LUAD_TCGA-44-8117-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.949804
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus of the optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01646
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.63765
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.944276
abducens nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.36582
QPCT	Pathway Commons Protein-Protein Interactions	1.0	null
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ACADM	Pathway Commons Protein-Protein Interactions	1.0	null
clotrimazole-6207	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HSP90AB1	Pathway Commons Protein-Protein Interactions	1.0	null
chr4_76356368_A_G_b38	GTEx eQTL 2025	1.0	2.11653
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.826819
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TECPR2	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSN	Pathway Commons Protein-Protein Interactions	1.0	null
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLINT1	Pathway Commons Protein-Protein Interactions	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2992-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mitochondrial proton-transporting ATP synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.716
SP1	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE237040_4_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
sarcolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.175188
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LHX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84531
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.956044
RAC2 GTPase cycle	Reactome Pathways 2024	1.0	null
GSE208350_4_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE111035,GSE111040_8_v_12_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEP3B217	CCLE Cell Line Gene Expression Profiles	1.0	1.36066
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Mitochondrial respiratory chain complex I	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.541
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSDL2	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13392
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RNF168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7621
levocabastine-7009	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-NI-A8LF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221327_4_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
tanespimycin-831	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5065
HROB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46146
SNU886	CCLE Cell Line Gene CNV Profiles	-1.0	-1.89099
LOXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0741
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.48556
ficolin-1-rich granule	GO Cellular Component Annotations 2023	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-1017-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213650_0_v_1_everolimus_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178340_1_v_6_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SQSTM1	Pathway Commons Protein-Protein Interactions	1.0	null
RPL10L	Pathway Commons Protein-Protein Interactions	1.0	null
PRPF6	Pathway Commons Protein-Protein Interactions	1.0	null
DAZAP1	Pathway Commons Protein-Protein Interactions	1.0	null
RPL5	Pathway Commons Protein-Protein Interactions	1.0	null
PELO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31859
GAPDH	Pathway Commons Protein-Protein Interactions	1.0	null
EFM19_BREAST	CCLE Cell Line Proteomics	1.0	2.92046
SRC-2_KO_GDS5087_485_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
valproic acid-6974	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06409
prednisolone-2393	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
OPM-2	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.63162
Perturb_6869_OE_STBD1_SRP316253	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	19.5229
KARPAS422	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7408
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88582
GSE188774_1_v_0_hkdc1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PUF60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22155
CCC5	DepMap CRISPR Gene Dependency	1.0	2.82791
GSE146982_4_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.40701
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38309
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
XAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62171
Omegasome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.932
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04188
RPS23	Pathway Commons Protein-Protein Interactions	1.0	null
naloxone-1506	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.166
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-Unnamed_4_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
SRC-2_Deficiency_GDS5087_270_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE195559_0_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SEC23A	Pathway Commons Protein-Protein Interactions	1.0	null
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	1.0	1.45432
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5580-01A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139987_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
C14orf166	Pathway Commons Protein-Protein Interactions	1.0	null
UNC13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66503
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
sirolimus-1646	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
t69-brown-adipose_female_8w	MoTrPAC Rat Endurance Exercise Training	-1.0	-1.39162
liver cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.320227
LPS6	DepMap CRISPR Gene Dependency	1.0	4.70604
trimipramine-3342	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCOA7	Pathway Commons Protein-Protein Interactions	1.0	null
SNU423	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70401
PIP	Pathway Commons Protein-Protein Interactions	1.0	null
RBMXL2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
haloperidol-6203	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.940394
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26D-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-27b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vacuolar membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.569
tretinoin-5208	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RPL21	Pathway Commons Protein-Protein Interactions	1.0	null
oxybutynin-7126	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24526
Lung squamous cell carcinoma_LUSC_TCGA-37-3789-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2087	CCLE Cell Line Gene Expression Profiles	1.0	1.60077
hsa-miR-302c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
tretinoin-3165	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K36me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217071_1_v_2_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_body_RS411_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
bupropion-6256	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
trazodone-2379	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
t69-brown-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.68859
GSE114013,GSE114014_0_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LH-01A-21R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33897
GATA5_KO_GDS4809_170_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-5147-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.27744
carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053571
TP53INP2_KO_GDS5053_277_mouse_Skeletal muscle - SKM-KO	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE196699_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147834_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.059584
MCCC2	Pathway Commons Protein-Protein Interactions	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
GSE125782_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Skeletal muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.167
WDHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91661
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20136
TGFBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66591
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.9982
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18095
MAP1B	Pathway Commons Protein-Protein Interactions	1.0	null
Hematuria	CTD Gene-Disease Associations	1.0	1.24433
RPS6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU520	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61413
BRIX1	Pathway Commons Protein-Protein Interactions	1.0	null
496100349_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.34866
GABARAPL1	Pathway Commons Protein-Protein Interactions	1.0	null
GCDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06618
CRCGN015_MCF10A_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13587
RDX	Pathway Commons Protein-Protein Interactions	1.0	null
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.565
Lung adenocarcinoma_LUAD_TCGA-55-8207-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF2AK2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE235390_4_v_0_lurbinectedin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1941
DYNC1LI1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NANOG	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-7554-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KCNIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07089
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.512
NCIH1373	CCLE Cell Line Gene CNV Profiles	1.0	1.95704
adrenosterone-5045	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
USE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74597
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30576
GABARAPL1	Hub Proteins Protein-Protein Interactions	1.0	null
ZC3H4	Pathway Commons Protein-Protein Interactions	1.0	null
dorsolateral part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1285
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE136627_3_v_1_hdac4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28444
timolol-5280	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLRG1	Pathway Commons Protein-Protein Interactions	1.0	null
PSMB1	Pathway Commons Protein-Protein Interactions	1.0	null
TCFL5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.803
PRKCZ	Pathway Commons Protein-Protein Interactions	1.0	null
liothyronine-2984	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.27258
sirolimus-1148	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TE-12	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.68651
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ENO1	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H8-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:H13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40387
SP in perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.64066
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RXRA-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Immune System Diseases	CTD Gene-Disease Associations	1.0	1.3414
GSE125862_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.32647
CEBPB-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MTDH	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SVIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00638
LGI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39423
Innate Immune System	Reactome Pathways 2024	1.0	null
Steatotic liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
orbital frontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.858807
C-4-I	COSMIC Cell Line Gene Mutation Profiles	1.0	null
methapyrilene-3205	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cisplatin_mus musculus_gpl339_gds3099	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Breast Neoplasms	CTD Gene-Disease Associations	1.0	1.29875
procaine-1674	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXOSC3	Pathway Commons Protein-Protein Interactions	1.0	null
CANX	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9170563-12885_2022_9665_MOESM3_ESM.docx-0-Candidata_target_genes_of_CEBPB_7_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
RPL22	Pathway Commons Protein-Protein Interactions	1.0	null
RFC5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE193541_1_v_2_nifurtimox_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A42Z-01A-12R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO320	CCLE Cell Line Gene CNV Profiles	1.0	1.39551
Perturb_13006_KO_C3_SRP235282	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.07343
HLC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.55036
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LA-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89839
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.954468
piroxicam-7445	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56682
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.62494
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30706
furaltadone-2554	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09214
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.515
COLO775	CCLE Cell Line Gene Expression Profiles	1.0	1.47396
rosiglitazone-5230	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50376
GPR63	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92711
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.34547
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integral component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CTPS1	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51775
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPLP2	Pathway Commons Protein-Protein Interactions	1.0	null
adenocarcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055262
GSE168797_1_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
MDA-MB-436	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998961
GSE186633_2_v_0_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
YWHAE	Pathway Commons Protein-Protein Interactions	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42513
LU65_LUNG	CCLE Cell Line Proteomics	1.0	3.08133
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.887442
HSP90B1	Pathway Commons Protein-Protein Interactions	1.0	null
hep-g2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.262986
Prostate adenocarcinoma_PRAD_TCGA-VN-A88R-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE120200,GSE127269_1_v_2_asxl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203308_9_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPL10A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SNRNP70	Pathway Commons Protein-Protein Interactions	1.0	null
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
t56-vastus-lateralis_female_4w	MoTrPAC Rat Endurance Exercise Training	-1.0	-2.22792
GSE149075_6_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CLTCL1	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_2876_Mut_KRAS_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
SRSF11	Pathway Commons Protein-Protein Interactions	1.0	null
Glycogen storage disease I	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.233
NPM1	Pathway Commons Protein-Protein Interactions	1.0	null
DHX30	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-LT-A5Z6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tanespimycin-5223	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
6841_PSMA1_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.18404
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUFM	Pathway Commons Protein-Protein Interactions	1.0	null
GSE101239_5_v_1_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ATG2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41167
GSE196117_6_v_7_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF638	Pathway Commons Protein-Protein Interactions	1.0	null
GSE115395_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04659
YTHDC2	Pathway Commons Protein-Protein Interactions	1.0	null
clozapine-6188	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86515
intermediate stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18944
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YL-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DSP	Pathway Commons Protein-Protein Interactions	1.0	null
dyclonine-7261	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mantle zone of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17604
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 895.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09817
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1181
retrorsine-2784	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PRPF38B	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203308_7_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69696
SMARCC2	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPK	Pathway Commons Protein-Protein Interactions	1.0	null
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB	ChEA Transcription Factor Targets	1.0	null
hsa-miR-4668-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A48J-01A-21R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160373_1_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38466
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158632_3_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
HS 255.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.90634
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32893
HNRNPD	Pathway Commons Protein-Protein Interactions	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_4_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NT5C3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01154
DMRT1	ChEA Transcription Factor Targets	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.9994
GSE183251_4_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HSD17B4	Pathway Commons Protein-Protein Interactions	1.0	null
Carcinoma	CTD Gene-Disease Associations	1.0	1.03641
APLP2_KO_GDS4414_534_mouse_adult cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
azapropazone-3143	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
quipazine-7240	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
chloroquine-7251	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
glucan catabolic process	GO Biological Process Annotations 2023	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.296
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pyridoxine-2751	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3777-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NASH_Liver_GSE24807	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.08411
GSE258991_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
metolazone-6292	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DUSP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59778
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7915-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OV2008/C13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
E2F6	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN014_HEPG2_24H:G23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26329
POLR2A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE218879_1_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-6215-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7984
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.338
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TF	Pathway Commons Protein-Protein Interactions	1.0	null
GCM2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9214
EOL1	CCLE Cell Line Gene CNV Profiles	1.0	1.47149
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN011_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7137
dimethadione-4607	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
flufenamic acid-5059	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044759
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CKAP4	Pathway Commons Protein-Protein Interactions	1.0	null
Perinuclear region of cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.817
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.900995
SRSF4	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Right atrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.11
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962583
PML	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_15527_OE_CPT1A_SRP292168	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.40355
hsa-miR-520b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE140441_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRP63-18441228-KERATINOCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32525
AMMECR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19375
PMC10861538-41467_2024_45669_MOESM7_ESM.xlsx-Sheet1-Supplementary_Data_4_DEGs_upon_KD_of_EVT_TFs_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BACE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32642
single-organism process	GO Biological Process Annotations 2015	1.0	null
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vacuolar lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.164
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
muscle system process	GO Biological Process Annotations 2015	1.0	null
EXOSC10	Pathway Commons Protein-Protein Interactions	1.0	null
AMPD1	Pathway Commons Protein-Protein Interactions	1.0	null
trichostatin A-6993	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RPS19	Pathway Commons Protein-Protein Interactions	1.0	null
CTBP2	ENCODE Transcription Factor Targets	1.0	null
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16348
Urinary Bladder Neoplasms	CTD Gene-Disease Associations	1.0	1.20622
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.00928
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HI-7171-01A-12R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4QX-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1793	CCLE Cell Line Gene Expression Profiles	1.0	1.35099
MAT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71858
18318837-TableS1	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
loxapine-1516	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
GSE107594_0_v_1_hmga2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r8 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39815
KRT9	Pathway Commons Protein-Protein Interactions	1.0	null
TUHR14TKB	DepMap CRISPR Gene Dependency	1.0	9.76644
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Matrix fibroblast_Lung_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
MAPK1_knockdown_45_GSE12291	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.258
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14703
trichostatin A-6439	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09795
ANKRD27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35883
SRSF7	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HNRNPC	Pathway Commons Protein-Protein Interactions	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RA-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSPH1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
WFS1_KO_GDS4526_111_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-US-A77G-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute pancreatitis_Pancreas_GSE3644	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.48945
GSE48812_11_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7585-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE136742,GSE136744_2_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Papillary Carcinoma of the Thyroid_Thyroid Gland (MMHCC)_GSE3467	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.96616
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6959-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
SSB	Pathway Commons Protein-Protein Interactions	1.0	null
GATA5_KO_GSE47425_50_mouse_lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MORC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20563
GSE150669_0_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HUH7	CCLE Cell Line Gene Expression Profiles	1.0	1.79432
PRH2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE148066,GSE157787_8_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.65227
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.35174
PMC11059513-mmc1.xlsx-Supplementary_Table1-Table_S1_The_gene_profile_was_down-regulated_after_HIF1A_was_knocked_down_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
ABCB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02265
NDUFAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27963
MSH6	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE211425_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.561
Mediodorsal nucleus of the thalamus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28696
PHGDH	Pathway Commons Protein-Protein Interactions	1.0	null
GSE226249_0_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Demyelinating Diseases	CTD Gene-Disease Associations	1.0	1.07947
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
ANXA1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE129241_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
glycophagy	GO Biological Process Annotations 2025	1.0	null
GSE178340_7_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
kawain-2337	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN012_HEPG2_24H:J21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.24773
Gastrointestinal Diseases	CTD Gene-Disease Associations	1.0	1.10942
hsa-miR-374a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
hsa-miR-1236	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
TIAL1	Pathway Commons Protein-Protein Interactions	1.0	null
heart	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.444884
hsa-miR-3688-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
EGR-1_KO_GDS3607_525_mouse_Retina - 30 Days (POST-NATAL)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vorinostat-1000	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
urapidil-3078	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
R121919	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.99
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.311
UM-UC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24159
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.37776
famotidine-1946	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anteroventral nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15056
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3699
CRCGN017_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.06302
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06817
GSE193999,GSE194000_4_v_0_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ficolin-1-rich granule membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CLTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1986
CEBPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47669
H6PD_KO_GDS3195_603_mouse_Skeletal muscle - Tibialis anterior	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.25191
RAF1_overexpression_220_GSE42964	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.97493
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-302a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
SMIM14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35664
SAP30	ENCODE Transcription Factor Targets	1.0	null
RPL28	Pathway Commons Protein-Protein Interactions	1.0	null
t-tubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.396648
ZFC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9783
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_EVT-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CIRBP	Pathway Commons Protein-Protein Interactions	1.0	null
MT-ND4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25762
facial motor nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75881
KRT78	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZM-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LYAR	Pathway Commons Protein-Protein Interactions	1.0	null
SPI1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL35A	Pathway Commons Protein-Protein Interactions	1.0	null
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.96052
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN011_HEPG2_24H:H04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1736
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126776_0_v_1_pelp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRPF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.3922
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
SNU840	DepMap CRISPR Gene Dependency	1.0	3.0274
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998961
WBP2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RPL31	Pathway Commons Protein-Protein Interactions	1.0	null
oxprenolol-5871	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE148200_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
flunarizine-7013	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.835491
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_Deficiency_GDS4856_318_mouse_Soleus skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DOK1	Pathway Commons Protein-Protein Interactions	1.0	null
levocabastine-7249	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
apomorphine-1505	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
estradiol-1182	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cardiovascular Diseases	CTD Gene-Disease Associations	1.0	1.33701
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2A_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
KNS60	DepMap CRISPR Gene Dependency	1.0	2.11775
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22251
CRCGN017_MCF10A.TP53.M_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.10937
ARG1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN014_HEPG2_24H:H21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43459
Liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
GSE231648_4_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BFTC-909	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998961
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.28898
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chloropyrazine-6227	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
nicardipine-6297	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.327164
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
SMC1A	Pathway Commons Protein-Protein Interactions	1.0	null
emetine-4243	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE130081,GSE130082_0_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207301,GSE207303_0_v_3_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPS20	Pathway Commons Protein-Protein Interactions	1.0	null
GSE158320,GSE183351_2_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
G361	CCLE Cell Line Gene CNV Profiles	1.0	1.39835
Bladder Urothelial Carcinoma_BLCA_TCGA-H4-A2HO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.1472
ANXA4	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.3189
lateral part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06367
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
AHCTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04565
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10434_KO_PPFIA1_SRP127326	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.90382
GSE246195,GSE246305_1_v_0_sin3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80749
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mafenide-1441	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
glycogen metabolic process	GO Biological Process Annotations 2025	1.0	null
H3K4me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RHOG GTPase cycle	Reactome Pathways 2024	1.0	null
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
isthmic part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6124
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.939462
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT5A-24692510-EPITHELIUM-MOUSE-MAMMARY	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_15282_KD_Kdm4a_SRP223217	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.71416
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18612
Plantaris muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.593
LIM1215	COSMIC Cell Line Gene Mutation Profiles	1.0	null
UNC80	Pathway Commons Protein-Protein Interactions	1.0	null
GSE223908,GSE223909_4_v_8_serpinb3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HADHA	Pathway Commons Protein-Protein Interactions	1.0	null
YBX1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE71529,GSE71558_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25407
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SETDB1_KO_GSE40296_7_mouse_brain (telencephalon)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-4795-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
aim	GeneRIF Biological Term Annotations	1.0	null
PK45H	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61781
POU3F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02798
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBNA1BP2	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_11122_KD_Eif3m_SRP162708	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.06711
TUBB1	Pathway Commons Protein-Protein Interactions	1.0	null
GLI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4422
Dorsal peduncular area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.9298
Lung squamous cell carcinoma_LUSC_TCGA-22-4601-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN011_HEPG2_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18535
mantle zone of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03284
nomifensine-7217	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
GSE161846,GSE161849_4_v_0_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MATK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30598
U2SURP	Pathway Commons Protein-Protein Interactions	1.0	null
Hypotension	CTD Gene-Disease Associations	1.0	1.02933
binding	GO Molecular Function Annotations 2015	1.0	null
Liver Diseases	CTD Gene-Disease Associations	1.0	1.88458
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11579
hsa-miR-375	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
H3K56ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04706
Precommissural nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25678
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PKM	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.71485
GSE185519_3_v_7_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lysosomal storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.388
CRCGN016_MCF10A.WT.HP_24H:L11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34059
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50096
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CD4_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.33269
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10324
aminocaproic acid-3122	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CAL27	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55641
GSE115763_3_v_1_klf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_MCF10A.WT.HP_24H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.27594
Ocular Motility Disorders	CTD Gene-Disease Associations	1.0	1.15357
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.892755
PRDX1	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PFN2	Pathway Commons Protein-Protein Interactions	1.0	null
ERMES complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.116
mitoxantrone-3232	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACOX1	Pathway Commons Protein-Protein Interactions	1.0	null
Motor neuron disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.274
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20353
SPI1	ChEA Transcription Factor Targets	1.0	null
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15671
MCAD_KO_GDS4546_423_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DGAT2L7P	Pathway Commons Protein-Protein Interactions	1.0	null
Phagophore assembly site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.963
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE86507,GSE86509_7_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126463_6_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ID4_KO_GDS4178_620_mouse_Splenic B cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
mitochondria-associated endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.976
DHX35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3011
ALB	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2GZ-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE240645_1_v_0_u90926_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_4_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_8056_KD_IGF2BP1_SRP094100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.332294
H3K27ac_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PPP2CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07474
ALDOC	Pathway Commons Protein-Protein Interactions	1.0	null
trichostatin A-873	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SUDHL4_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	9.9601
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050471
thiethylperazine-6232	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
Disease Models, Animal	CTD Gene-Disease Associations	1.0	1.21823
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.67058
A673	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78808
NFIC_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.40401
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
budesonide-6330	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
carisoprodol-1314	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN015_MCF10A_48H:A07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33545
Prostatic Neoplasms	CTD Gene-Disease Associations	1.0	1.14268
ZC3HAV1L	Pathway Commons Protein-Protein Interactions	1.0	null
H3K56ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
etifenin-2838	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
SIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40351
HDAC1	ENCODE Transcription Factor Targets	1.0	null
DDOST	Pathway Commons Protein-Protein Interactions	1.0	null
KRT35	Pathway Commons Protein-Protein Interactions	1.0	null
PPP2CA	Pathway Commons Protein-Protein Interactions	1.0	null
496100640_PCx_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.29698
Perturb_6904_KD_OTX2_SRP347033	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05948
GSE146982_4_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199538,GSE199539_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
demeclocycline-2545	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PUF60	Pathway Commons Protein-Protein Interactions	1.0	null
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2774
IRF1	ENCODE Transcription Factor Targets	1.0	null
DNAJC10	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.42133
SR-95639A-1336	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
LMO2-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.53
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
raphe nuclei of medulla	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.85515
GSE153189_1_v_0_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE255432_6_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Storage tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
DUSP22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18479
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE165647_5_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE96991,GSE97117_5_v_1_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ozagrel-7281	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Anus Neoplasms	CTD Gene-Disease Associations	1.0	1.08868
RPS4X	Pathway Commons Protein-Protein Interactions	1.0	null
MAP1LC3B	Hub Proteins Protein-Protein Interactions	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08422
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Arsenic	CTD Gene-Chemical Interactions	1.0	null
R3HDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54425
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.8656
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
COL9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1343
Sarcoma_SARC_TCGA-WK-A8XZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMB5	Pathway Commons Protein-Protein Interactions	1.0	null
RPP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44798
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
NCI-H345	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12092
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051704
medial mammillary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18065
Perturb_6249_KO_Chrna7_SRP338769	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE130081,GSE130082_5_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
icSARS CoV_3Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.601446
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062092
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2563
Sarcoma_SARC_TCGA-DX-A7EL-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCIXC	DepMap CRISPR Gene Dependency	1.0	6.65747
enilconazole-6518	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.46597
MCM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3264
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14844
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.940566
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A2QR-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1-25329375-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
androsterone-1296	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Nerve Degeneration	CTD Gene-Disease Associations	1.0	1.21984
Perturb_8704_KD_SIRT1_SRP267968	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.92115
PNISR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73249
CRCGN017_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.00839
Myocardial Infarction	CTD Gene-Disease Associations	1.0	1.052
periventricular stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81667
GBAS	Pathway Commons Protein-Protein Interactions	1.0	null
Liver Failure, Acute	CTD Gene-Disease Associations	1.0	1.17893
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
Overnutrition	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07837
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, barrel field	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11089
f2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
HOPS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.81
NBR1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE236437_2_v_1_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ionomycin-882	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mediodorsal nucleus of thalamus_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.956453
Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.20848
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RM-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CAMA-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.890057
CAL29	DepMap CRISPR Gene Dependency	1.0	3.37536
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
polysaccharide binding	GO Molecular Function Annotations 2015	1.0	null
GSE215314_0_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal part of alar p2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17604
genistein-1176	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE146982_4_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178340_7_v_6_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pentetic acid-3387	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6939-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.523588
GNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4756
GSE149000_2_v_0_cyp3a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PD-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
F36P_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	4.67913
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4302	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
P63-20808887-KERATINOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BT474	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
HSPA9	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC3355086-pgen.1002728.s003.xlsx-Tabelle1-HEY1_upregulated_HEY1	Rummagene Transcription Factor Associations 2026	1.0	null
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02998
Cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.20879
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34731
APLN_KO_GDS3228_601_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RAB11FIP5	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Nearest_Ensembl_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Associated_Gene_Name_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.900995
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A6B1-01A-12R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE226249_2_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	120.482
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77952
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perinuclear endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.949
Lung adenocarcinoma_LUAD_TCGA-55-7903-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4309	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.945696
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Glycogen storage disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.21
BCL-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.655
HEL9217_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.9131
GSE151412_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
15208663-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.56741
ZR-75-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.874917
PU.1-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r8 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19852
SCA1_Knock-in_GDS1756_232_mouse_Cerebellum tissue - 12 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE110268_1_v_3_foxd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
glis2_17618285_kidney_lof_mouse_gpl2897_gds2817	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.071229
paclitaxel-1959	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MALME3M	DepMap CRISPR Gene Dependency	1.0	3.64062
medial parabrachial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.82006
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
methyldopa-5272	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHRNB4_Deficiency_GDS2309_714_mouse_Brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Perturb_13119_KO_Dnajc11_SRP404364	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29775
TRA2A	Pathway Commons Protein-Protein Interactions	1.0	null
etodolac-7246	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SRP14	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158456_1_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DSG1	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7238-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trichostatin A-6820	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE207122_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31285
AIFM1	Pathway Commons Protein-Protein Interactions	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
NIPSNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7152
LC1F	CCLE Cell Line Gene CNV Profiles	1.0	1.56518
Anorexia	CTD Gene-Disease Associations	1.0	1.14302
plasma membrane part	GO Cellular Component Annotations 2015	1.0	null
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1783	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.13561
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
LOVO	DepMap CRISPR Gene Dependency	1.0	2.52907
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PDXK	Pathway Commons Protein-Protein Interactions	1.0	null
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03545
Ascites	CTD Gene-Disease Associations	1.0	1.44982
trichostatin A-1284	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KRT85	Pathway Commons Protein-Protein Interactions	1.0	null
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Chlorsulfuron	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.25
YBX3	Pathway Commons Protein-Protein Interactions	1.0	null
dizocilpine-5746	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5701-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
Superior colliculus, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56891
Brain - Cortex	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.593516
SLC25A5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE162015_2_v_0_nfkb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE188869,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148695,GSE167281_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13783
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3198	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
KRT14	Pathway Commons Protein-Protein Interactions	1.0	null
RUFY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35019
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Perturb_7002_KO_Acadl/Acadvl_SRP323582	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE184892_0_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.954542
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46E-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POM121C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2595
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38584
Progressive myoclonus epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.136
SU-DHL-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69838
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXO1_KD_GDS2720_478_mouse_LSK	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TRAP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_0_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_241_KD_Blimp1_SRP094038	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GUCY2F	Pathway Commons Protein-Protein Interactions	1.0	null
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2895-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.14214
Perturb_3_KO_Cnot6l_SRP152802	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.22132
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.36896
GSE148010,GSE148120_3_v_2_tet2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.92906
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SF295_CENTRAL_NERVOUS_SYSTEM	CCLE Cell Line Proteomics	1.0	9.50955
SPI1-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP4	Pathway Commons Protein-Protein Interactions	1.0	null
macroautophagy	GO Biological Process Annotations 2025	1.0	null
HNRNPR	Pathway Commons Protein-Protein Interactions	1.0	null
GSE137653_2_v_3_siglecf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.84924
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20N-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K20me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211128_9_v_5_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171486_4_v_0_ddx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.971845
TRIB1_KO_GDS2944_555_mouse_Macrophages	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EH-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inappropriate ADH Syndrome	CTD Gene-Disease Associations	1.0	1.23899
UBA52	Pathway Commons Protein-Protein Interactions	1.0	null
H4K20me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE85880,GSE85881_4_v_2_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.135888
PARP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28964
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of isBL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16169
HNRNPDL	Pathway Commons Protein-Protein Interactions	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-6771-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1755	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_18390_KO_923_SRP286259	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.13808
Novikoff hepatoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.684
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.862329
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN012_HEPG2_24H:G04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08378
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02235
KRT31	Pathway Commons Protein-Protein Interactions	1.0	null
H3K79me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cisplatin_mus musculus_gpl339_gse6206	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RNF19B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04796
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cholestasis	CTD Gene-Disease Associations	1.0	1.14404
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05054
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10324
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11093
KRT77	Pathway Commons Protein-Protein Interactions	1.0	null
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RUBCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03961
BACH1	ENCODE Transcription Factor Targets	1.0	null
PROCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19055
SPSB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40368
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7659-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
isthmic part of basolateral isthmic reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16077
flupentixol-5307	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_2874_Mut_KRAS_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
TAF15	Pathway Commons Protein-Protein Interactions	1.0	null
SEC23B	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4799-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mitochondrial pyruvate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.614
RANBP6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE225218_8_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
chr4_76356471_G_T_b38	GTEx eQTL 2025	1.0	1.26413
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13079
10-methoxyharmalan-6355	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
MTF2	ChEA Transcription Factor Targets	1.0	null
OTX2_KO_GDS4440_424_mouse_brain (fourth ventricular choroid plexus)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
WDR82	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15671
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE188382_4_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
tertiary granule	GO Cellular Component Annotations 2023	1.0	null
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66681
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.963795
ATP6V0D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11551
KE39	CCLE Cell Line Gene CNV Profiles	1.0	1.73329
testis	HPA Tissue Protein Expression Profiles	1.0	1.00184
TUBB4B	Pathway Commons Protein-Protein Interactions	1.0	null
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.834231
GSE233256_0_v_1_rbms1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chaperone-mediated autophagy translocation complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.518
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_3_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
pallidal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03284
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ENO2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.426
CALML5	Pathway Commons Protein-Protein Interactions	1.0	null
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.43755
TGM2_KD_GSE23702_715_human_NB4 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.944977
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09337
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.71399
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
laterodorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27846
GSE145628,GSE145629_1_v_0_myrf_human	RummaGEO Gene Perturbation Signatures	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	2.43104
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Lytic vacuole membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.606
AGO1	Pathway Commons Protein-Protein Interactions	1.0	null
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lidoflazine-6278	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S05_LF_C2_3h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
PCBP1	Pathway Commons Protein-Protein Interactions	1.0	null
Glioblastoma multiforme cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.658
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.34599
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.904207
OCILY10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.94814
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40145
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
arcuate nucleus of medulla, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15734
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4713-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1PZ-01A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-630	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Lung squamous cell carcinoma_LUSC_TCGA-77-A5G1-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199874_3_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Prostate adenocarcinoma_PRAD_TCGA-KK-A59X-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TUBA1C	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A724-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SGTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76218
CAV3_Deficiency_GDS3552_558_mouse_Hearts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7253
SFPQ	Pathway Commons Protein-Protein Interactions	1.0	null
ATP5L	Pathway Commons Protein-Protein Interactions	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TENM3	Pathway Commons Protein-Protein Interactions	1.0	null
Muscle	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TEX10	Pathway Commons Protein-Protein Interactions	1.0	null
SSBP1	Pathway Commons Protein-Protein Interactions	1.0	null
indometacin-7409	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
C18orf32	Pathway Commons Protein-Protein Interactions	1.0	null
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
EFM19	CCLE Cell Line Gene CNV Profiles	1.0	1.47222
cv-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.179847
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUP160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27652
RBM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21033
RPS16	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-617	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PAQR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41274
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE132759_4_v_2_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134412_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRKAG1	Pathway Commons Protein-Protein Interactions	1.0	null
GNG14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83444
MYB	ChEA Transcription Factor Targets	1.0	null
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07224
PABPC1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE218171_1_v_0_foxn3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE195568_2_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sphingolipidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.369
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
naftidrofuryl-5287	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral (non-cerebellar) part of isA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43897
intermediate stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84698
doxorubicin_mus musculus_gpl8321_gse17115	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.860452
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-11A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RAB3GAP2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.50331
GSE143406_1_v_0_carfilzomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HNRNPA3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BT-474	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
Brain Lower Grade Glioma_LGG_TCGA-DU-6402-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC2966110__F8	PFOCR Pathway Figure Associations 2024	1.0	null
GSE211177,GSE211178_9_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
naltrexone-5765	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Edema	CTD Gene-Disease Associations	1.0	1.5745
Vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.24158
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
GSE210655_1_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_8705_KD_SIRT1_SRP267968	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.21244
Lateral habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4247
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.0246
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DUXB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93697
GSE231524,GSE231526_0_v_1_dusp6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
clemastine-7443	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE185944_2_v_3_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
INA6	DepMap CRISPR Gene Dependency	1.0	2.11669
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RBM39	Pathway Commons Protein-Protein Interactions	1.0	null
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.836888
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RPL36	Pathway Commons Protein-Protein Interactions	1.0	null
SAMHD1	Pathway Commons Protein-Protein Interactions	1.0	null
ARF1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE119978,GSE180930_6_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SiHa	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.50325
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.47202
TMEM87B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26031
isthmic vestibulocerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51009
RAB1A	Pathway Commons Protein-Protein Interactions	1.0	null
r7 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11486
smarcc2_00000000_e12dot5_embryonic_cortex_lof_mouse_gpl6887_gse45629	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.188363
POU2F1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
RPS11	Pathway Commons Protein-Protein Interactions	1.0	null
OPM2	CCLE Cell Line Gene Expression Profiles	1.0	2.97921
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15511
dorsolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.23943
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02168
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146074_9_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221020,GSE221023_2_v_1_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11022
lateral anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95539
Cognition Disorders	CTD Gene-Disease Associations	1.0	1.42428
NCOA2_KO_GDS5087_24_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE215086_0_v_1_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
EJM	CCLE Cell Line Gene Expression Profiles	1.0	1.50646
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EVSA-T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.903156
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.10518
dextromethorphan-1281	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
glycophagy	GO Biological Process Annotations 2023	1.0	null
SF3B3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE88819_5_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
3t6	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.536
GSE207914_3_v_6_nudt7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE189859,GSE189861_3_v_2_idh1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6188-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-302b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HNF4A_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE129241_4_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
HNRNPA2B1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HSPA6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cell Transformation, Neoplastic	CTD Gene-Disease Associations	1.0	1.49278
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.078
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.903869
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GRWD1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-3622a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Lung adenocarcinoma_LUAD_TCGA-97-8547-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.832641
EXOSC4	Pathway Commons Protein-Protein Interactions	1.0	null
G3BP1	Pathway Commons Protein-Protein Interactions	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trichostatin A-6874	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC12513837-41588_2025_2336_MOESM4_ESM.xlsx-Supplementary_Table_1-Supplementary_Table_1_List_of_AR-only_and_p300_AR-shared_enhancer_regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SF3B4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEx Heart 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	-1.0	-3.4187
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.36454
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
TXN	Pathway Commons Protein-Protein Interactions	1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236437_0_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GABARAP	Hub Proteins Protein-Protein Interactions	1.0	null
DSG4	Pathway Commons Protein-Protein Interactions	1.0	null
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.56847
ADAMTS15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51669
FNBP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE165682_4_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DCAF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26419
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE239844_4_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.29385
GSE189609_1_v_2_hax1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.75881
KMM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15401
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANKEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35823
Endoplasmic reticulum	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PMC12748338-12672_2025_4052_MOESM1_ESM.docx-0-CEBPB_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
DENND10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9445
LDHA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE151829,GSE151831_5_v_8_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43102
GSE211128_7_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NSMAF	Pathway Commons Protein-Protein Interactions	1.0	null
mantle zone of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01259
GABARAPL2	Pathway Commons Protein-Protein Interactions	1.0	null
SERPINB13	Pathway Commons Protein-Protein Interactions	1.0	null
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063231
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195786_0_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CCT2	Pathway Commons Protein-Protein Interactions	1.0	null
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.896985
Prostate adenocarcinoma_PRAD_TCGA-G9-6338-01A-12R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
benserazide-5322	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-449c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.900995
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anchored component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.822
homatropine-1848	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RPL7A	Pathway Commons Protein-Protein Interactions	1.0	null
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18848
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Nearest_Ensembl_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5291205-srep41905-s3.xlsx-LPS_datasets_gmx-Unnamed_3_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GPI	Pathway Commons Protein-Protein Interactions	1.0	null
PDS5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40863
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Barrington's nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51839
Exercise induced circadian regulation	WikiPathways Pathways 2024	1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.86949
PRDX3	Pathway Commons Protein-Protein Interactions	1.0	null
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.27641
FBL	Pathway Commons Protein-Protein Interactions	1.0	null
GSE144443_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
WDR5	Pathway Commons Protein-Protein Interactions	1.0	null
RPS9	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-8_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
SUPHD1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70165
MYB-21317192-ERMYB-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48999
haloperidol-1024	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
clozapine-1009	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
chlorphenesin-2115	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INAVA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28084
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42148
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
isoxicam-7268	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV2::FIGLA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.1894
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.53144
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95847
Sarcoma_SARC_TCGA-WK-A8XS-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38757
GSE151119_2_v_1_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Anterior hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01404
FRK	MSigDB Cancer Gene Co-expression Modules	1.0	null
ZNF510	Pathway Commons Protein-Protein Interactions	1.0	null
PMC9927941-jci-133-163612-s045.xlsx-Sheet1-Table_S11_DEGs_with_a_PAX5_binding_motif_as_identified_by_Pscan_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
RPS7	Pathway Commons Protein-Protein Interactions	1.0	null
CD4_Memory_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.39983
RANBP2	Pathway Commons Protein-Protein Interactions	1.0	null
periventricular stratum of r1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48418
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE227592_0_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
MHHES1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61048
GSE191037_0_v_1_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
WDR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26542
CRCGN009_HEPG2_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19195
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PPIL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59717
GSE207301,GSE207303_1_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
phenylpropanolamine-5298	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NR2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88045
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.958281
TYK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22466
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32599
PPP1CC	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LC-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.326067
yy1_22711985_skeletal_muscle_lof_mouse_gpl8321_gse39009	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.766889
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RPF2	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPU	Pathway Commons Protein-Protein Interactions	1.0	null
MYL6	Pathway Commons Protein-Protein Interactions	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7125_KO_Prkce_SRP049245	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.86763
GSE206270_2_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cvt vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.503
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_15175_KD_LOC157273_SRP238261	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.89902
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149264,GSE149267_2_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
moracizine-3520	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
LSM2	Pathway Commons Protein-Protein Interactions	1.0	null
ST486	CCLE Cell Line Gene Expression Profiles	-1.0	-2.14336
RPS8	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-5428-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TUBE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6376
Perturb_14246_KO_FOXM1_SRP328179	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
PATU8902	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44734
fenofibrate-2401	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DHX36	Pathway Commons Protein-Protein Interactions	1.0	null
betulin-3513	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CDK4	Pathway Commons Protein-Protein Interactions	1.0	null
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC12824706-BLOOD_BLD-2025-028441-mmc3.xlsx-Fig4B_genes_inc_expr_NRF1-gene_name_NRF1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205163,GSE205164_3_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
practolol-4603	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.2465
SERPINB4	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6754502-41598_2019_50051_MOESM3_ESM.xlsx-Br_to_Fay_Thermoneutral_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
SRSF3	Pathway Commons Protein-Protein Interactions	1.0	null
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
UBF1/2-26484160-CHIP-SEQ-HMECS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE206870,GSE206872_0_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE129287_0_v_1_cd200_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.1578
ELAVL1	Pathway Commons Protein-Protein Interactions	1.0	null
nucleus-vacuole junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.838
HSPA1B	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
alfuzosin-5242	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.879471
Type 2 diabetes mellitus_Renal Tissue_GSE642	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.85248
ARID1B	Pathway Commons Protein-Protein Interactions	1.0	null
CAT	Pathway Commons Protein-Protein Interactions	1.0	null
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50852
CAD	Pathway Commons Protein-Protein Interactions	1.0	null
levamisole-7450	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-CEM_ect_TET2_DEGs_DMRs_hDMRs-CCRF-CEM_EV_vs_ectopic_TET2_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
locus coeruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9723
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
orbital frontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.89223
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55425
FLNB	Pathway Commons Protein-Protein Interactions	1.0	null
mediodorsal nucleus of thalamus_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.845806
CRCGN010_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.45675
ELK3-25401928-HUVEC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_11255_KO_Nr5a2_SRP131036	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.48705
BLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89549
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34496
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.43499
GSE124471,GSE124488_2_v_3_lats1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.6091
Movement disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193541_0_v_3_nifurtimox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WDR45B	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Carbohydrate binding module family 20	InterPro Predicted Protein Domain Annotations	1.0	null
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13148
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-520a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GARS	Pathway Commons Protein-Protein Interactions	1.0	null
AMO1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71516
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4789-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02353
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04303
EXOSC1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.813213
PAICS	Pathway Commons Protein-Protein Interactions	1.0	null
medial (magnocellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36312
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	144.544
PMC6145927-41467_2018_5729_MOESM6_ESM.xlsx-TF_Activity_Genesets-FRA1_DN_FOSL1	Rummagene Transcription Factor Associations 2026	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANXA7	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SH2D3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0554
HNRNPA0	Pathway Commons Protein-Protein Interactions	1.0	null
phenacetin-2471	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.35734
hsa-miR-20a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10471
habenula (old epithalamus)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17454
DNAJA1	Pathway Commons Protein-Protein Interactions	1.0	null
PTGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41038
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5468-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.834659
GSE149903_0_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HUT102	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64903
Glycogen storage disease II	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.911
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7108
valproic acid-1163	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
propofol-5306	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Heart Diseases	CTD Gene-Disease Associations	1.0	1.46568
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
Hepatitis	CTD Gene-Disease Associations	1.0	1.12391
Cytoplasmic vesicle membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SEC24B	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM104B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80008
SOX9	ChEA Transcription Factor Targets	1.0	null
GSE213228_4_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MEC2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72009
GSE114992,GSE114993_7_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KRT2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE114013,GSE114014_1_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCP1	Pathway Commons Protein-Protein Interactions	1.0	null
phthalylsulfathiazole-3033	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07547
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33654
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.767
protein binding	GO Molecular Function Annotations 2015	1.0	null
GSE184356_3_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
APLP2_KO_GDS4414_536_mouse_adult cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
mefloquine-6205	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cinoxacin-5783	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE214505_0_v_1_akr1b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5732738-oncotarget-08-103415-s002.xlsx-MFC-7_DEGs-Genes_with_significantly_different_expression_between_parental_MCF-7_and_GATA3_WT_clones_with_adjusted_P_value_0_05_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE109285_5_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CCNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04909
indoprofen-3007	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PPARGC1B_Hypomorphic Mutation_GDS2515_695_mouse_Skeletal muscle - (quadriceps muscles)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
RAB8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46424
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WN-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.998135
LY-294002-5236	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.49077
NUP214	Pathway Commons Protein-Protein Interactions	1.0	null
Left_Ventricle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.35255
tanespimycin-986	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DDX27	Pathway Commons Protein-Protein Interactions	1.0	null
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.43461
dorsal lateral geniculate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30458
periventricular stratum of m2AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02255
CALR	Pathway Commons Protein-Protein Interactions	1.0	null
FAM72D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40037
GSE121824,GSE121826_0_v_2_scaf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01611
GSE118766_2_v_3_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-XBP1_XBP1	Rummagene Transcription Factor Associations 2026	1.0	null
Superior vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04239
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01218
GSE228181_0_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34583
PEER	CCLE Cell Line Gene CNV Profiles	1.0	1.96359
KD	DepMap CRISPR Gene Dependency	1.0	4.9751
RALBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18362
16581771-tableS1a	GeneSigDB Published Gene Signatures	1.0	null
niridazole-2440	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prefoldin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.763
hsa-miR-4793-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PNPLA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2262
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UN-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE206270_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.14269
MRPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0514
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PMC8803621-mmc6.xlsx-Sup_Fig5A_genes_list-Genes_with_following_MEF2_motifs_around_their_TSS_CTAWWWATA_RSRFC4_Q2_MEF2_Q6_01_MEF2_03_MEF2_02_RSRFC4_Q2_from_GSEA_MEF2A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.32188
Rectum adenocarcinoma_READ_TCGA-AF-5654-11A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE254770_0_v_1_sin3b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE89154_1_v_3_proscillaridin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Parkinson Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
DSC2	Pathway Commons Protein-Protein Interactions	1.0	null
EXOSC9	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A.WT.HP_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.55568
Perturb_2053_KD_TPR_SRP217733	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.26229
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX17	Pathway Commons Protein-Protein Interactions	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.454
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01195
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SBNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45307
terazosin-2530	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_10727_KO_Mettl14_SRP282531	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.77
GSE202434,GSE202438_15_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
PSMC4	Pathway Commons Protein-Protein Interactions	1.0	null
FLNA	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney Tubular Necrosis, Acute	CTD Gene-Disease Associations	1.0	1.22501
DUT	Pathway Commons Protein-Protein Interactions	1.0	null
15546871-Table1S	GeneSigDB Published Gene Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K8-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
RPL30	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_16404_KO_Klhl41_SRP100902	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.36787
Brooke-Spiegler syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0695
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ChaGo-K-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.7467
EFTUD2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE160373_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SQLE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02354
GSE147876,GSE147877_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
U2AF2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE188869,GSE188871_2_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autoimmune Diseases	CTD Gene-Disease Associations	1.0	1.24496
layer III of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.990743
amitriptyline-1701	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TUSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02178
alfaxalone-3135	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE226091,GSE226092_3_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
saquinavir-6246	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
16707422-tableS1b	GeneSigDB Published Gene Signatures	1.0	null
SNU761	CCLE Cell Line Gene Expression Profiles	1.0	2.54685
H3K79me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSTA	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.TP53.M_24H:H10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.349
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04485
Hemolysis	CTD Gene-Disease Associations	1.0	1.28518
MAP1LC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4279
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01218
Glycogen storage disease Ib	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.067
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
nomegestrol-6362	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	193.01
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.895732
GSE153443_1_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Atg12-Atg5-Atg16 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.956
NKRF	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE194396,GSE194429_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DT-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
aminohippuric acid-6294	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.62609
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
scopoletin-3131	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE141328_3_v_2_rock2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42131
Temporal association areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01692
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFV	Pathway Commons Protein-Protein Interactions	1.0	null
ROS50	DepMap CRISPR Gene Dependency	1.0	4.40735
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
probenecid-4771	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCBP1	Pathway Commons Protein-Protein Interactions	1.0	null
Autolysosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.355
CFL1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE147366_1_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral part of r1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21997
hsa-miR-519d	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14333
Proteinuria	CTD Gene-Disease Associations	1.0	1.7183
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_2875_Mut_KRAS_SRP404927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
WDR62	Pathway Commons Protein-Protein Interactions	1.0	null
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199541_2_v_4_mbd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.605
CRCGN016_MCF10A.TP53.M_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.24278
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-3_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Prestwick-689-7173	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Fluorouracil	CTD Gene-Chemical Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.89556
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIST2H2BE	Pathway Commons Protein-Protein Interactions	1.0	null
RCN2	Pathway Commons Protein-Protein Interactions	1.0	null
Cleft Palate	CTD Gene-Disease Associations	1.0	1.18193
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.223906
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20985
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Secretory granule membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
TELO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61126
PRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82182
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPL23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64262
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHSA8926	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.43126
DAOY	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54234
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-372	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
EJM	DepMap CRISPR Gene Dependency	1.0	11.5326
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-6_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10334
levocabastine-2948	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7161353-supp_073353.119_Supplemental_Tab_S8.xlsx-BRCA_HRGs_correlation_to_MBNL2-gene_name_MBNL2	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_15401_KD_MELK_SRP098926	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.11075
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.165435
PRMT5	Pathway Commons Protein-Protein Interactions	1.0	null
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6275
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28059
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5484
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Neoplasms	CTD Gene-Disease Associations	1.0	1.71728
KCNIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52961
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DLAT	Pathway Commons Protein-Protein Interactions	1.0	null
GSE160246_9_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRSF10	Pathway Commons Protein-Protein Interactions	1.0	null
ergocalciferol-5346	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
T-tubule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
SQ1	CCLE Cell Line Gene CNV Profiles	1.0	1.52631
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BICR31	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
DDB1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE210842_3_v_1_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.076
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0233
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE196117_1_v_7_clarithromycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Otx2_KO_GDS4440_143_mouse_fourth ventricular choroid plexus tissue	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCI-H2081	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02866
EXOC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62063
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.10306
Duchenne muscular dystrophy (DMD)_Muscle - Striated (Skeletal) (MMHCC)_GSE1025	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.53615
KBTBD6	Pathway Commons Protein-Protein Interactions	1.0	null
sulfadimidine-2560	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19677
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039442
SSR4	Pathway Commons Protein-Protein Interactions	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02426
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TARDBP	Pathway Commons Protein-Protein Interactions	1.0	null
trichostatin A-448	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7731-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIA1_KO_GSE54418_263_mouse_spinal cord	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE88819_1_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SYNCRIP	Pathway Commons Protein-Protein Interactions	1.0	null
Aflatoxin B1	CTD Gene-Chemical Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-UZ-A9PO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182179_0_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_11337_KD_Ankrd35_SRP214047	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE153189_1_v_3_interferon gamma_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ketoconazole-1285	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CCT6A	Pathway Commons Protein-Protein Interactions	1.0	null
paclitaxel-5320	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RPS15A	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN008_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.05055
Neurotoxicity Syndromes	CTD Gene-Disease Associations	1.0	1.60921
CNOT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64595
H3K9ac_Peripheral Blood Mononuclear Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.55187
CRCGN008_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.0555
PMC9376070-41419_2022_5157_MOESM18_ESM.xlsx-Sheet1-Table_S4_Differentially_expressed_genes_of_HNRNPC-KD_and_NC_cells_identified_in_the_RNA-seq_analysis_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5174-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE173997_1_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE126463_5_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE195568_3_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32632
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6U0-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-550a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K36me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211177,GSE211178_8_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPS24	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABARAP	Pathway Commons Protein-Protein Interactions	1.0	null
ATP5B	Pathway Commons Protein-Protein Interactions	1.0	null
SDHA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE161302,GSE161304_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBOAT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07476
Perturb_8043_KO_Zeb2_SRP261907	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.45687
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4983-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perinuclear region of cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE60837_2_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
rolipram-3072	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
LY-294002-1157	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UBL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08962
GSE220520_3_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PPP2R1A	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_16406_KO_Vgll2_DRP005135	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.54553
GSE205316,GSE205317_0_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB-20176806-THIOMACROPHAGE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
propoxycaine-6803	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38515
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140200_1_v_3_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SARS-CoV MA15_Day1-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.01787
KDM5A	ENCODE Transcription Factor Targets	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
naftifine-2974	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.900784
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05024
norfloxacin-7283	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14819
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.142
NCIH441	CCLE Cell Line Gene Expression Profiles	1.0	1.62864
GSE95077_1_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-302e	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Parkinson's disease 6	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
GSE228106_0_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K029AX	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45371
GSE114258_1_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_4_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.851016
tanespimycin-6985	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21086
BUB3	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.67718
HNF4A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hif1a_16565084_mcf7_lof_human_gpl2507_gds2761	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.221706
hsa-miR-520d-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFKB1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE66931,GSE73382_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB7A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paraventricular nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.76498
cardiac muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.334498
Lung squamous cell carcinoma_LUSC_TCGA-56-8201-11A-01R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Perturb_1027_KO_Ovgp1_SRP379795	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.81928
trichostatin A-4184	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4222
GSE243683_0_v_1_s100a16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K36me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE167224,GSE168147_3_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.16318
NUDT21	Pathway Commons Protein-Protein Interactions	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	2.04541
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.515
r3 pontine raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1825
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HYOU1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE104508_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.78428
HDAC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59961
CRCGN015_HEPG2_48H:B19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50192
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYK_knockdown_190_GSE54065	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.41433
GSE217071_3_v_2_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CSNK2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02177
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16134
hsa-miR-1972	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
SAFB2	Pathway Commons Protein-Protein Interactions	1.0	null
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8413-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR1H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31261
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PSMA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52871
bupivacaine-2404	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACADM_KO_GDS4546_512_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ATG2A	Pathway Commons Protein-Protein Interactions	1.0	null
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.04232
ATG4B	Pathway Commons Protein-Protein Interactions	1.0	null
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43279
VZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.963261
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.41883
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCF-STTG1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3385-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE82032_3_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCBD1	Pathway Commons Protein-Protein Interactions	1.0	null
mantle zone of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22039
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:L21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0184
496100451_TCx_no dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.34558
ethaverine-5337	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chr4_76276244_A_G_b38	GTEx eQTL 2025	1.0	1.8169
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02353
EXOSC2	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MU-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cinoxacin-3463	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885868
CP-944629-7502	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CADM1_Deficiency_GDS2027_722_mouse_Testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Poisoning	CTD Gene-Disease Associations	1.0	1.24623
NUP88	Pathway Commons Protein-Protein Interactions	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03937
496100630_PCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28315
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PBX-27287812-CHIP-SEQ-EMBYONIC-LIMB-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SKMM2	CCLE Cell Line Gene Expression Profiles	1.0	1.83481
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDCD6	Pathway Commons Protein-Protein Interactions	1.0	null
procainamide-2618	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49708
IPO5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09342
RPL18	Pathway Commons Protein-Protein Interactions	1.0	null
Colon - Sigmoid	GTEx Tissue Gene Expression Profiles 2023	1.0	5.24332
FHL2_Deficiency_GDS3344_596_mouse_Spontaneously immortalized embryonic fibroblasts (EFs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE152666,GSE152668_2_v_1_carm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ADCK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81958
Ovarian Neoplasms	CTD Gene-Disease Associations	1.0	1.39841
spinalcordlower	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.916787
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.847243
CD8_Naive_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.88665
primary auditory cortex (core)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.59145
DDX1	Pathway Commons Protein-Protein Interactions	1.0	null
HIST1H1C	Pathway Commons Protein-Protein Interactions	1.0	null
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3393
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RHOA GTPase cycle	Reactome Pathways 2024	1.0	null
GSE193258,GSE193259_9_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5334
RUFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27202
GMPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79825
MOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41683
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
MYB-21317192-ERMYB-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Left atrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.024
Lung squamous cell carcinoma_LUSC_TCGA-39-5011-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TNRC6B	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE145476_2_v_0_hopx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.921489
CPSF6	Pathway Commons Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.47271
Lung Injury	CTD Gene-Disease Associations	1.0	1.43537
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.832641
ZNF263	ENCODE Transcription Factor Targets	1.0	null
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE218907_3_v_2_opa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3470785-NIHMS377161-supplement-3.pdf-497-NR5A2_NR5A2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
oleandomycin-1518	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216538_1_v_6_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Anterolateral visual area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62814
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN010_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14384
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DDX3X	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RM-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
carbarsone-1313	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PRKAR1A	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nutrition disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
skeletal muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.612555
HSPA7	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A61C-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02418
GSE228106_3_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
latamoxef-3028	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A2OS-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.836818
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPS13	Pathway Commons Protein-Protein Interactions	1.0	null
GSE111035,GSE111040_8_v_9_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AAK1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211474,GSE212779_8_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
isthmic portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20912
sirolimus-7001	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
pyrithyldione-7153	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNRPD3	Pathway Commons Protein-Protein Interactions	1.0	null
pentoxyverine-5610	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042005
GSE88819_7_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229973_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H1F0	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-multicellular organism process	GO Biological Process Annotations 2015	1.0	null
TTBK2	Pathway Commons Protein-Protein Interactions	1.0	null
chenodeoxycholic acid-7310	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
16651409-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
lytic vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.365477
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178714_3_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE225141,GSE225143_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211177,GSE211178_8_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UACC-257	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998961
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.008
Electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.71
AGL	Pathway Commons Protein-Protein Interactions	1.0	null
THOC6	Pathway Commons Protein-Protein Interactions	1.0	null
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37263
PRRC2C	Pathway Commons Protein-Protein Interactions	1.0	null
lateral part of preisthmic periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02203
intrinsic component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
X-linked dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DDX5	Pathway Commons Protein-Protein Interactions	1.0	null
RRS1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC3607232-mmc1.xls-MLLN_prom_RS411-MLL_prom_RS411_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.96371
496100625_FWM_no dementia_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.70606
GSE232624_4_v_5_ethanol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nigrostriatal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
11-deoxy-16,16-dimethylprostaglandin E2-7519	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HSPA1L	Pathway Commons Protein-Protein Interactions	1.0	null
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15861
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE9375	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.72228
Perturb_15393_KD_CHKA_SRP050331	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	15.4173
GSE162892_3_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162087_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FLNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40881
pyrvinium-2957	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SNU-423	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998961
GSE138019_1_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAB15	Pathway Commons Protein-Protein Interactions	1.0	null
GSE124410_1_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.33115
GSE88819_0_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.53108
MINDY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97713
mafenide-5079	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
adenosine phosphate-5359	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SLC43A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03362
IZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6165
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
IZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.133
Glycogen storage disease III	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.779
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FXR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27286
CPSF1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC8298514-41467_2021_24813_MOESM22_ESM.xlsx-RXRA_H3K27ac-SYMBOL_RXRA	Rummagene Transcription Factor Associations 2026	1.0	null
Anterior hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.24385
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126127_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050739
Pancreatic adenocarcinoma_PAAD_TCGA-H6-A45N-11A-12R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE199606_1_v_0_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ascorbic acid-6306	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7918
ascorbic acid-3225	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43523
SEC24A	Pathway Commons Protein-Protein Interactions	1.0	null
Midbrain trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.41386
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFC1	Pathway Commons Protein-Protein Interactions	1.0	null
ZC3H12C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.782
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.8998
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13582
Drug-Related Side Effects and Adverse Reactions	CTD Gene-Disease Associations	1.0	1.88008
PMC10204296-13578_2023_1034_MOESM16_ESM.xlsx-Black-ZNF671_ZNF671	Rummagene Transcription Factor Associations 2026	1.0	null
octopamine-3112	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055858
CYP4Z2P	Pathway Commons Protein-Protein Interactions	1.0	null
HARA	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62443
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.38517
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
C8orf33	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-3171	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
FOXA1	ENCODE Transcription Factor Targets	1.0	null
CRCGN015_HEPG2_48H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.95392
EIF5A2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Peroxisomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.645
superficial stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0478
iopanoic acid-6348	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
U2AF1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.87855
F7	Pathway Commons Protein-Protein Interactions	1.0	null
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
chlorpropamide-6291	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.83071
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fluphenazine-6954	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE125153_2_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
glycogen binding	GO Molecular Function Annotations 2023	1.0	null
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.01936
GSE122101,GSE122103_3_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HNRNPUL1	Pathway Commons Protein-Protein Interactions	1.0	null
KRT80	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE262134_0_v_1_dnajc12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PSMB2	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EX-01A-12R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AGO2	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lateral terminal nucleus of the accessory optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04138
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Exercise-induced Circadian Regulation(Mus musculus)	WikiPathways Pathways 2014	1.0	null
SRF	ENCODE Transcription Factor Targets	1.0	null
CTCF_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL23A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.62182
liver cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058421
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.98283
HIST1H4F	Pathway Commons Protein-Protein Interactions	1.0	null
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054002
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.71513
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.649
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
RPS14	Pathway Commons Protein-Protein Interactions	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EXOSC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21307
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120612_7_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216413_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58641
diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.215314
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypoglossal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32041
isthmus proper	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02805
GSE142210_11_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KRT82	Pathway Commons Protein-Protein Interactions	1.0	null
parabrachial complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66778
E2F4	ENCODE Transcription Factor Targets	1.0	null
Twitch muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.322
plasma membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38494
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88582
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ZIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22653
Perturb_2076_OE_PUM1_SRP072710	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.409
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5655
Hyponatremia	CTD Gene-Disease Associations	1.0	1.18456
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5039-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-544	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.8656
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-MV-A51V-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FLG2	Pathway Commons Protein-Protein Interactions	1.0	null
SLC35E4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14501
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24159
hsa-miR-93	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GLA	Pathway Commons Protein-Protein Interactions	1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3451
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GYG1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE190186,GSE190188_8_v_5_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_4485_OE_Mir29a/Mir29b1_SRP220351	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.30059
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7469-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE85880,GSE85881_4_v_1_tretinoin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Fast twitch muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
HCC44	DepMap CRISPR Gene Dependency	1.0	2.31608
VWA5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45622
EEF1A1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE126463_6_v_2_arid2_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07501
Glycosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.123
GABARAPL2	Hub Proteins Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4151-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Myocarditis	CTD Gene-Disease Associations	1.0	1.01701
PEBP1	Pathway Commons Protein-Protein Interactions	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7918-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12478272-mmc1.xlsx-Table_S7-Supplementary_Table_7_Proteome-wide_MR_and_sensitivity_analysis_results_using_the_brain_pQTL_dataset_from_Wingo_et_al_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
parasubthalamic nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02805
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.838754
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RTCB	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-K2-ATF3_peaks_Context1_2-Gene_Name_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
MYH9	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-8460-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052905
Prenatal Injuries	CTD Gene-Disease Associations	1.0	1.11911
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08477
VAPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53273
GSE254649_2_v_1_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA1_01_233	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.95654
KMS34	CCLE Cell Line Gene Expression Profiles	1.0	2.0772
Sublaterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33024
NIF3L1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_1_BioID_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Combined-MYB_Combined_sgRNA_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCT7	Pathway Commons Protein-Protein Interactions	1.0	null
GSE182179_2_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPS25	Pathway Commons Protein-Protein Interactions	1.0	null
Variable age at onset electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.129
Acute Myeloid Leukemia_LAML_TCGA-AB-2814-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149124,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193900,GSE193905_1_v_0_pura_human	RummaGEO Gene Perturbation Signatures	1.0	null
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.48456
Lung squamous cell carcinoma_LUSC_TCGA-22-5483-01A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mildronate	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.23
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CRCGN015_MCF10A.TP53.M_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.82455
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KARPAS-422	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.80773
tertiary granule membrane	GO Cellular Component Annotations 2025	1.0	null
KEAP1	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-27a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE169152_5_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fulvestrant-1146	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SLC25A27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92626
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052043
Weight Gain	CTD Gene-Disease Associations	1.0	1.5012
CBR3	Pathway Commons Protein-Protein Interactions	1.0	null
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02985
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07432
FOXA1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Glucose Intolerance	CTD Gene-Disease Associations	1.0	1.36361
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
haloperidol-1628	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SRF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Adipocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
CTCF-31629814-HEPATOCYTES-MOUSE-TYROSINEMIA	ChEA Transcription Factor Targets 2022	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1518
PMC9794594-DataSheet_1.xlsx-ST12-Unnamed_9_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
difenidol-7406	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE196962_4_v_3_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25995
pentetrazol-2092	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Parabrachial nucleus, medial division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99711
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE201309_5_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4683
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16332
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33281
RHO GTPase cycle	Reactome Pathways 2024	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y6-01A-21R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integral component of plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GSE168797_1_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Acute Kidney Injury	CTD Gene-Disease Associations	1.0	1.4332
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urinary bladder	HPA Tissue Protein Expression Profiles	1.0	1.00184
ILF3_02_148	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61891
GSE184210_0_v_1_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
Dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
CRCGN013_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53814
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.87769
GSE118766_2_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5B_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUBB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7536
CARM1	Pathway Commons Protein-Protein Interactions	1.0	null
SPI1-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
XRCC6	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DDX24	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IL-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE114258_3_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
layer II of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.917838
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
GSE178714_6_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240896,GSE240899_2_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5004-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7389
SJRH30	CCLE Cell Line Gene CNV Profiles	1.0	1.68519
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRMT1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE248858_1_v_7_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7210-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
umbilicalcord	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.939637
Perturb_773_Mut_ACLY_SRP403241	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.08494
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.48068
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.2876
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
trichostatin A-6434	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE159473_0_v_1_eif5a2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173810_4_v_6_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CUL3	Pathway Commons Protein-Protein Interactions	1.0	null
minocycline-2405	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41569
COR-L279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.900619
KRT10	Pathway Commons Protein-Protein Interactions	1.0	null
RPL3	Pathway Commons Protein-Protein Interactions	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
midbrain raphe nuclei	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.19749
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE92364_1_v_3_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67682
Mental Disorders	CTD Gene-Disease Associations	1.0	1.32905
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-MJ-A68H-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TDOTT	DepMap CRISPR Gene Dependency	1.0	2.3316
Perturb_15422_KD_PXN_SRP199368	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.33222
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_788_KD_Foxk2_SRP145105	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE163809_1_v_2_sdhaf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6135
MAPK14_KO_GDS2693_535_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NAP1L1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR1A	Pathway Commons Protein-Protein Interactions	1.0	null
Ventromedial hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.59485
GSE165122_2_v_1_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLDN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31205
H1FX	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
PSMC3	Pathway Commons Protein-Protein Interactions	1.0	null
Hypertension_Adrenal gland_GSE1674	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.76339
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TMEM160	Pathway Commons Protein-Protein Interactions	1.0	null
MOLM16_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	3.7763
Uterine Cervical Neoplasms	CTD Gene-Disease Associations	1.0	1.09436
OXA1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32198
nilutamide-3104	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE210476_2_v_0_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PABPN1	Pathway Commons Protein-Protein Interactions	1.0	null
496100408_PCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.23828
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dl-alpha tocopherol-1320	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153871_0_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MYOD1	ENCODE Transcription Factor Targets	1.0	null
ATR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83225
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
496100353_HIP_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.34476
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Atg1/ULK1 kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.407
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CBS	Pathway Commons Protein-Protein Interactions	1.0	null
nabumetone-5428	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sarcoma_SARC_TCGA-PC-A5DP-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE147283_1_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_ENSEMBL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
IZ in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842778
Fetal Death	CTD Gene-Disease Associations	1.0	1.42777
DMS114	CCLE Cell Line Gene CNV Profiles	-1.0	-2.62451
furazolidone-3019	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE258991_5_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111385_2_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8054_KD_IGF2BP1_SRP094100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.77255
EMC-BAC-2	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.65801
GSE126463_0_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
dexamethasone_homo sapiens_gpl6480_gds3946	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	2.59807
KU812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07654
gabarapl1	GeneRIF Biological Term Annotations	1.0	null
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.825252
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TP53INP2_KO_GDS5053_544_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SDHB	Pathway Commons Protein-Protein Interactions	1.0	null
GSE232223_1_v_0_letmd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6397
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3454-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2	ChEA Transcription Factor Targets	1.0	null
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE254649_3_v_1_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZFP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.72907
GSE220520_3_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25666
Diurnally Regulated Genes with Circadian Orthologs(Mus musculus)	WikiPathways Pathways 2014	1.0	null
RPL14	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE125782_0_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FAM98A	Pathway Commons Protein-Protein Interactions	1.0	null
clopamide-6301	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUPT1	DepMap CRISPR Gene Dependency	1.0	2.06597
GSE199092_1_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
SMARCB1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61277
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885868
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35905
ACACA	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3064-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.193083
GSE202434,GSE202438_8_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PGC-1alpha_Deficiency_GDS4904_311_mouse_Aged gastrocnemius muscle - 24 months	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69949
GATA5_KO_GSE47425_386_mouse_lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC10714175-mmc2.xlsx-KD_Gene_list-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16681
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10583
ATP5O	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPA1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN013_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30918
hsa-miR-4503	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
MYB-26560356-CHIP-SEQ-TH2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE134214_0_v_1_ell2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80993
Nervous System Diseases	CTD Gene-Disease Associations	1.0	1.77724
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAPZB	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24159
HSPA4	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SRSF5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE180200,GSE180201_15_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4147
C1QBP	Pathway Commons Protein-Protein Interactions	1.0	null
Neutrophil degranulation	Reactome Pathways 2024	1.0	null
FAM169A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96955
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
TIA1	Pathway Commons Protein-Protein Interactions	1.0	null
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.22862
intermediate stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34401
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FUS	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-7938-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RMDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22207
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LI-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040712
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178340_1_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
eed_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.018244
496100499_PCx_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12933
GSE48812_4_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
Parabrachial nucleus, lateral division, dorsal lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52247
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chr4_76424241_C_T_b38	GTEx eQTL 2025	1.0	1.31774
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE44157,GSE44163_1_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
trichostatin A-7387	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BMI1	ChEA Transcription Factor Targets	1.0	null
SOX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70188
GSE179031_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE232558_0_v_2_fbxl12_human	RummaGEO Gene Perturbation Signatures	1.0	null
trichostatin A-6709	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
basal ganglia disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.266558
PCBP2	Pathway Commons Protein-Protein Interactions	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
H3K36me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pattern binding	GO Molecular Function Annotations 2015	1.0	null
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PKP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE153871_5_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Adrenocortical carcinoma_ACC_TCGA-PK-A5H9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36806
POLR3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2642
ifosfamide-6279	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	1.0	null
KRT3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Huntington's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.888469
ventral tuberomammillary nucleus, superficial part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04927
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
hydroxyzine-2024	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RBM14	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.835004
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.536
PMC9745174-Table_3.xlsx-GSE8157-turquoise-ZBTB38_ZBTB38	Rummagene Transcription Factor Associations 2026	1.0	null
GSE124304_1_v_0_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19Q-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
Endometrial glandular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.002
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
DLD	Pathway Commons Protein-Protein Interactions	1.0	null
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PHB	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Smooth endoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.295
KRT71	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_11435_KD_CIT_SRP173646	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.32209
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
20101236-SuppTable7a	GeneSigDB Published Gene Signatures	1.0	null
PLS3	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6405-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
terminal subparaventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01404
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041642
GSE145790_0_v_1_bruceantin_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.974948
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2361
NCIH1836	CCLE Cell Line Gene CNV Profiles	1.0	1.54214
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HMY1	DepMap CRISPR Gene Dependency	1.0	4.10777
496100417_HIP_probable Alzheimer's disease_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.35037
HAUS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77891
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10S-01A-22R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RT-112	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-1_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4680-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CRCGN015_HEPG2_48H:B22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.53694
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.890057
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NDUFS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00852
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.61604
PMC9235320-mmc2.xlsx-ST9_eQTL-MR-results-Unnamed_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
IARS	Pathway Commons Protein-Protein Interactions	1.0	null
KBTBD7	Pathway Commons Protein-Protein Interactions	1.0	null
DCTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77771
sulfamethoxazole-2335	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UDP-N-acetylglucosamine-lysosomal-enzyme N-acetylglucosaminephosphotransferase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.507
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.058775
Flight muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.686
SUPT16H	Pathway Commons Protein-Protein Interactions	1.0	null
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27403
Runx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.13
AHCY	Pathway Commons Protein-Protein Interactions	1.0	null
KRT6C	Pathway Commons Protein-Protein Interactions	1.0	null
RPL24	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN008_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57635
EEF1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	9.0061
hsa-miR-4723-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
SRRT	Pathway Commons Protein-Protein Interactions	1.0	null
RO60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66146
MTHFD1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.72538
genistein-6194	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MSTN_DEPLETION_GDS3637_94_mouse_mature skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HLA-B	Pathway Commons Protein-Protein Interactions	1.0	null
skeletal muscle	HPA Tissue Protein Expression Profiles	1.0	1.00184
CTCF	ENCODE Transcription Factor Targets	1.0	null
GSE208634_1_v_2_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE197850_4_v_0_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
Anteroventral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.00656
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MC-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3145_KO_Mrfta/Mrtfb_SRP388810	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.31337
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23888
HEP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.900995
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-373	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
CEBPD	ENCODE Transcription Factor Targets	1.0	null
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.01445
PRDX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69769
NUBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00056
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18095
RT11284	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4314
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Depressive Disorder	CTD Gene-Disease Associations	1.0	1.58327
GSE196671_6_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MRPS12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55971
troglitazone-1173	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tertiary granule	GO Cellular Component Annotations 2025	1.0	null
FLCN	Pathway Commons Protein-Protein Interactions	1.0	null
GSE227891_5_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
estradiol-1241	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
WFS1_KO_GSE33372_395_mouse_hypothalamus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC5095001-oncotarget-07-36293-s002.xlsx-Table_S2-Table_S2_MYCN-correlated_genes_and_their_correlations_with_other_transcription_factors_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
TUBA4A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE95685_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72507
r8 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18985
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.805561
UBA5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE144443_10_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EP300	ChEA Transcription Factor Targets	1.0	null
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.997
BCLAF1_01_214	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.89715
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	2.32785
RPL13	Pathway Commons Protein-Protein Interactions	1.0	null
GSE114284_1_v_3_irf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
cefapirin-3471	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MATR3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE193999,GSE194000_3_v_2_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC4051124-1471-2164-15-256-S16.XLSX-WES_IPD-RBCK1_2-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
95T1000	DepMap CRISPR Gene Dependency	1.0	4.17984
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21574
iopanoic acid-5448	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PSMA6	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH28	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45107
RPS10	Pathway Commons Protein-Protein Interactions	1.0	null
Tremor	CTD Gene-Disease Associations	1.0	1.12288
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE216273,GSE216292_0_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE180200,GSE180201_15_v_1_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
cantharidin-3075	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Tcf1_KO_GDS1473_307_mouse_Pancreatic islets	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.989946
GYS1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K79me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GRSF1	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RJ-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
glucan catabolic process	GO Biological Process Annotations 2025	1.0	null
alpha-estradiol-2670	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tretinoin-966	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCIH1963	CCLE Cell Line Gene Expression Profiles	-1.0	-1.47038
DYNC2I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55305
TTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7752
PANC-03-27	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
corbadrine-7208	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
atg8	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7406-11A-01R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
idazoxan-3088	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.903316
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anteromedial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19918
ZCCHC11	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	1.76452
FBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02571
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL7L1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CJ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Chromosome Aberrations	CTD Gene-Disease Associations	1.0	1.17695
TAGLN2	Pathway Commons Protein-Protein Interactions	1.0	null
epirizole-1681	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Heart Failure	CTD Gene-Disease Associations	1.0	1.07875
GSE131680_1_v_0_macroh2a1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LKAAEAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34651
EEF1A2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE169697,GSE169725_0_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184356_1_v_2_tfam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE261563_9_v_8_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160373_1_v_2_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24159
glycogen catabolic process	GO Biological Process Annotations 2025	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A8NY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FNIP1	Pathway Commons Protein-Protein Interactions	1.0	null
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043825
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Right_Atrium	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.42418
ATP6V1G2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ISTMEL1	DepMap CRISPR Gene Dependency	1.0	2.89143
HUPT4	DepMap CRISPR Gene Dependency	1.0	2.6652
IGF2BP2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95302_2_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TE15	CCLE Cell Line Gene CNV Profiles	1.0	1.3349
IGKV1-5	Pathway Commons Protein-Protein Interactions	1.0	null
LSM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3587
GSE115395_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PCI6A	DepMap CRISPR Gene Dependency	1.0	8.19177
GTEx AdiposeTissue 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-16.4883
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r7 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40896
GSE229973_4_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE102505_4_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
KRT4	Pathway Commons Protein-Protein Interactions	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053728
H3K27ac_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11062_KO_Jup/Ctnnb1_SRP304535	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-16.9382
VZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27315
spinalcordupper	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.14105
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL23	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10713
GEMIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26446
BTK_KO_GDS1346_302_mouse_splenic B cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PGK1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RNMT	Pathway Commons Protein-Protein Interactions	1.0	null
GSE130690,GSE130692_2_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
ZNF536	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27403
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE206226_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of r1BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82232
GSE226249_0_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
muscle contraction	GO Biological Process Annotations 2015	1.0	null
JURKAT, CLONE E6-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.223
GSE79291_1_v_2_streptozotocin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
trimetazidine-2876	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN012_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3764
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KHSRP	Pathway Commons Protein-Protein Interactions	1.0	null
central part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70478
LGALS3BP	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.36047
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
basolateral amygdaloid nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07432
HCC2998	DepMap CRISPR Gene Dependency	1.0	3.80328
hesperidin-5313	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07349
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Phosphatidylinositol 3-kinase complex, class III	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.777
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
meticrane-7282	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lysosomal lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.09
prednisolone-7424	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KRT76	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN008_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7108
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS123	DepMap CRISPR Gene Dependency	1.0	2.4385
alpha-ergocryptine-2572	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE100102_0_v_3_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Autophagosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.014
GSE216238,GSE216241_0_v_1_tonsl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Centronuclear myopathy 1	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.416
Lung adenocarcinoma_LUAD_TCGA-75-6207-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146074_9_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7161353-supp_073353.119_Supplemental_Tab_S8.xlsx-LUAD_HRGs_correlation_to_MBNL2-gene_name_MBNL2	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH292	DepMap CRISPR Gene Dependency	1.0	2.50999
propidium iodide-6277	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MS751	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12767
Perturb_13302_KO_Tet2_SRP338315	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.49319
KMS28BM	CCLE Cell Line Gene Expression Profiles	1.0	1.53463
DYX1C1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE213228_2_v_5_irak2_human	RummaGEO Gene Perturbation Signatures	1.0	null
glycogen metabolic process	GO Biological Process Annotations 2023	1.0	null
GSE193354_0_v_1_saraf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:M05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.11667
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNRPB	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.37144
motor nucleus of trigeminal nerve, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44616
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_16384_KO_Lincsmad7_SRP123056	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.54482
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:I22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43765
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5192-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PSMA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29567
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1-22570637-MALME-3M-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
AZGP1	Pathway Commons Protein-Protein Interactions	1.0	null
Mitochondrial cloud	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.575
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25853
GTF3C3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE100316_5_v_2_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.909342
MCM5	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-4316	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
GSE227592_10_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
COGN278	DepMap CRISPR Gene Dependency	1.0	2.48977
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4-II-E-C3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.132
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.05149
MDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15379
CREB1	ENCODE Transcription Factor Targets	1.0	null
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.83756
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
ATG7	Pathway Commons Protein-Protein Interactions	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.48
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3QU-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9068765-41467_2022_29960_MOESM14_ESM.xlsx-TP53-Annotation_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE207302,GSE207303_0_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:M01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.10435
HNRNPH2	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NUPL2	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_14680_KO_P2Y14_SRP044222	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.46934
valproic acid_mus musculus_gpl1261_gds3002	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE201042_2_v_4_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.60347
lateral medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12053
4950_MED27_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.05711
hsa-miR-4699-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114258_1_v_0_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135686_2_v_3_etomoxir_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCT3	Pathway Commons Protein-Protein Interactions	1.0	null
Muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
trichostatin A-4632	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE136894_1_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SERPINB2	Pathway Commons Protein-Protein Interactions	1.0	null
ONDA9	DepMap CRISPR Gene Dependency	1.0	3.05521
dorsomedial preoptic area, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.66074
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_11995_KO_C3_SRP235282	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Magnocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03545
HAT1	Pathway Commons Protein-Protein Interactions	1.0	null
LANCL1	Pathway Commons Protein-Protein Interactions	1.0	null
SUM229PE	DepMap CRISPR Gene Dependency	1.0	3.62823
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24575
NIX_Deficiency_GDS2630_655_mouse_Spleen	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
carbohydrate metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.18651
LGMN	Pathway Commons Protein-Protein Interactions	1.0	null
CLN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28765
SRSF2	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_13137_KO_Ing1_SRP149486	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.37602
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14335
Lung squamous cell carcinoma_LUSC_TCGA-22-5483-11A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.955409
KRT33B	Pathway Commons Protein-Protein Interactions	1.0	null
mepyramine-7223	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5191-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3118	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CRCGN017_MCF10A.WT.HP_24H:P15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5402
NCI-H2171	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE189609_1_v_0_hax1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPL13A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE162688_1_v_4_pink1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CCRF-SB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05979
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN012_HEPG2_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.01092
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148200_4_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111247_14_v_12_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GATA3_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.873188
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15671
NOM1	Pathway Commons Protein-Protein Interactions	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GW-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTBP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE132386_1_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A_48H:O12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.17771
CRCGN014_HEPG2_24H:F22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43527
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_7_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18398
coralyne-1298	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.17043
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.73682
PHB2	Pathway Commons Protein-Protein Interactions	1.0	null
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24891
Coma	CTD Gene-Disease Associations	1.0	1.16467
bendroflumethiazide-2555	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-4_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Amyotrophic lateral sclerosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3_OE_GDS3444_576_mouse_Cultured embryonic stem (ES) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ifosfamide-3485	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HSPE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27914
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041789
Prostate adenocarcinoma_PRAD_TCGA-KC-A4BL-01A-31R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-7_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Secretory vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
hsa-miR-3941	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SUDHL6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.78954
GSE248858_4_v_0_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50028
hsa-miR-324-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
multicellular organismal process	GO Biological Process Annotations 2015	1.0	null
trichostatin A-4072	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cefapirin-7142	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.900995
GSE104508_2_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Superior colliculus, zonal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67019
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RAB39A	Pathway Commons Protein-Protein Interactions	1.0	null
RPS18	Pathway Commons Protein-Protein Interactions	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.933215
mesoridazine-7017	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adipose - Visceral (Omentum)	GTEx Tissue Gene Expression Profiles 2023	1.0	2.57949
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nipecotic acid-3121	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
troglitazone-1012	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SRY	ChEA Transcription Factor Targets	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09464
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31093
etofylline-5048	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JUP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE226249_0_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.093773
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCIMY5	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42678
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
TATDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2876
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	108.35
BAG4	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
MARS	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PCMT1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4619_KD_Rfx1_SRP231452	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.28229
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
trichostatin A-4388	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Anteromedial visual area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10324
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154767_2_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
16-phenyltetranorprostaglandin E2-7546	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.90302
netilmicin-7302	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.434
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
meropenem-5824	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Atrium	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.11
Sarcoma_SARC_TCGA-DX-A48P-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130081,GSE130082_0_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
homatropine-5477	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCIH1435	CCLE Cell Line Gene CNV Profiles	1.0	2.15599
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131565_1_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prochlorperazine-1215	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
starch binding	GO Molecular Function Annotations 2015	1.0	null
GSE130620_1_v_0_kdm4b_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.8249
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE245407,GSE245412_0_v_1_smurf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998961
EIF2AK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1329
GATA2-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC25A6	Pathway Commons Protein-Protein Interactions	1.0	null
GSE125782_3_v_2_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49901
xylazine-2132	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.61814
GSE240896,GSE240899_10_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE187006_0_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Outer mitochondrial membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.046
ioxaglic acid-2966	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SKIV2L2	Pathway Commons Protein-Protein Interactions	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.61563
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02353
Leukopenia	CTD Gene-Disease Associations	1.0	1.03493
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43102
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998961
ILF2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN016_MCF10A.WT.HP_24H:O09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5265
GSE178714_3_v_0_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_2_TurboID_10m_ERM_proteome-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZNF577	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13735
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
19286929-SuppTable2q	GeneSigDB Published Gene Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-WA-A7GZ-11A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
APOBEC3B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE128730_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.849063
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KMS-26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.15874
ATP5A1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE178714_6_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Membrane fusion priming complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.455
CCK81	DepMap CRISPR Gene Dependency	1.0	3.00607
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE206270_1_v_0_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_13114_KO_Foxm1_SRP194062	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.8871
RPL36A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96495
Immune System	Reactome Pathways 2024	1.0	null
GSE205163,GSE205164_9_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06139
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE241031_0_v_4_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FGD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43259
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13751_KO_Bcl3_SRP179718	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.42803
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.824348
Acquired metabolic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE216538_0_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
acemetacin-6361	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-106b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Psoriasis vulgaris_Skin tissue_GSE13355	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.31279
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.4901
Glycogen Storage Disease	DisGeNET Gene-Disease Associations	1.0	null
sulconazole-3035	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
telenzepine-5521	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K36me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Starch grain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.674
CLIC1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE122101,GSE122103_0_v_1_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25048
GSE112962,GSE112963_2_v_1_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2826-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10714175-mmc2.xlsx-KD_Gene_list-Supplemental_Table_3_FAM13B_knockdown_mediated_changes_in_gene_expression_AR	Rummagene Transcription Factor Associations 2026	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12767
RPL37A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE147876,GSE147877_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:J01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.02715
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80265
HUG1N	CCLE Cell Line Gene CNV Profiles	-1.0	-2.89531
GSE147876,GSE147877_2_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
valproic acid-1665	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ESET_KO_GDS4508_348_mouse_Dorsal telencephalon from E14.5 embryos	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
LARP1	Pathway Commons Protein-Protein Interactions	1.0	null
MCM3	Pathway Commons Protein-Protein Interactions	1.0	null
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	76.4207
BTG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07865
MOLP-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11946
GSE217156_2_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_4_Overlap_of_ERM_proteom-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vascular Diseases	CTD Gene-Disease Associations	1.0	1.26298
WDR77	Pathway Commons Protein-Protein Interactions	1.0	null
HNRNPH1	Pathway Commons Protein-Protein Interactions	1.0	null
metyrapone-3070	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CW9019	DepMap CRISPR Gene Dependency	1.0	3.68483
pb1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.299
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07547
Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNRPE	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.306
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.989651
GSE146074_0_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3691
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNRPD1	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05486
RUNX3	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GPR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99741
RPL19	Pathway Commons Protein-Protein Interactions	1.0	null
isradipine-6347	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Hepatocellular adenoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.119
ficolin-1-rich granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
CDC5L	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
necessary	GeneRIF Biological Term Annotations	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M4-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100453_HIP_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.82749
betazole-6344	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KIF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29371
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43102
fluphenazine-6196	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MET_knockout_259_GSE25583	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.839136
RPL15	Pathway Commons Protein-Protein Interactions	1.0	null
SNRPD2	Pathway Commons Protein-Protein Interactions	1.0	null
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.905773
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37397
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.929194
GSE48812_7_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239457_1_v_0_rasa1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1092	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.850032
S100A8	Pathway Commons Protein-Protein Interactions	1.0	null
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.99456
ketorolac-5988	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCOA2_KO_GSE41558_19_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MRPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11983
PRKAA1	Pathway Commons Protein-Protein Interactions	1.0	null
HCC95	DepMap CRISPR Gene Dependency	1.0	3.47102
anisomycin-6764	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
galantamine-4772	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
extracellular region	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE197850_4_v_2_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18521
T3M3	DepMap CRISPR Gene Dependency	1.0	2.36833
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22778
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.968451
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Glycogen granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.695
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEFM	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NXF1	Pathway Commons Protein-Protein Interactions	1.0	null
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046831
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
15681518-Figure2	GeneSigDB Published Gene Signatures	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.9271
GSE108614,GSE108615_0_v_2_setd1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.7628
PMC9235320-mmc2.xlsx-ST9_eQTL-MR-results-Supplementary_Table_9A_The_effects_of_whole_blood_transcripts_on_COVID-19_severity_with_suggestive_Mendelian_randomization_evidence_P_0_05_using_Genomicc_data_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PRDX4	Pathway Commons Protein-Protein Interactions	1.0	null
TBC1D2B	Pathway Commons Protein-Protein Interactions	1.0	null
RAE1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE232558_0_v_1_fbxl12_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06817
cytoplasmic part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE173997_3_v_0_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.295851
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02717
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6222-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02756
GSE96991,GSE97117_5_v_0_il11_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Taenia tecta, dorsal part, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82362
Sarcoma_SARC_TCGA-K1-A3PN-02A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SULT1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0143
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.861658
PMC12804025-mmc2.xlsx-LPS-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
ficolin-1-rich granule	GO Cellular Component Annotations 2025	1.0	null
CAV1_KO_GDS3551_366_mouse_mouse heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DHX15	Pathway Commons Protein-Protein Interactions	1.0	null
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31112
Hypoglycemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.17
GSE165647_5_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.0522
H3K4ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Perturb_8367_KD_IGF2BP1_SRP094100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.7892
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
SNRPF	Pathway Commons Protein-Protein Interactions	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0479
Slow twitch muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.814
GSE161846,GSE161849_1_v_5_smarca4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Diseases	CTD Gene-Disease Associations	1.0	1.23899
RPL7	Pathway Commons Protein-Protein Interactions	1.0	null
GSE228162_2_v_5_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBC1D15	Pathway Commons Protein-Protein Interactions	1.0	null
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.6446
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ILF3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE154767_4_v_3_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
chlorambucil-4523	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178340_1_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
RPL27	Pathway Commons Protein-Protein Interactions	1.0	null
CSB-26484114-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AS-3778-01A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7727-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7882-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210655_1_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201309_1_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cefalexin-1273	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NSDHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02573
HNRNPF	Pathway Commons Protein-Protein Interactions	1.0	null
PCM6	CCLE Cell Line Gene Expression Profiles	1.0	1.85703
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE3583	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.990593
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.830105
flumetasone-3410	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLK	Pathway Commons Protein-Protein Interactions	1.0	null
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PTPLAD1	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN012_HEPG2_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5665
Lung Diseases	CTD Gene-Disease Associations	1.0	1.19412
TC32	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63752
SRSF1	Pathway Commons Protein-Protein Interactions	1.0	null
RUVBL2	Pathway Commons Protein-Protein Interactions	1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.94669
GNL3	Pathway Commons Protein-Protein Interactions	1.0	null
milrinone-3552	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RPS6KB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62361
KRT16	Pathway Commons Protein-Protein Interactions	1.0	null
GSE184892_0_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13090_KO_Atm_SRP062722	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K27me3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GPC4	Pathway Commons Protein-Protein Interactions	1.0	null
intrinsic component of plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ALDH3A2	Pathway Commons Protein-Protein Interactions	1.0	null
RFC4	Pathway Commons Protein-Protein Interactions	1.0	null
H3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16309
RPL18A	Pathway Commons Protein-Protein Interactions	1.0	null
L363	CCLE Cell Line Gene Expression Profiles	1.0	1.80541
C2orf81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19609
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1787
18081427-TableS8	GeneSigDB Published Gene Signatures	1.0	null
fludrocortisone-282	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KP1N	DepMap CRISPR Gene Dependency	1.0	5.10396
CRCGN009_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23784
5213008-898	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
18310505-TableS1	GeneSigDB Published Gene Signatures	1.0	null
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146074_10_v_8_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHLA266	DepMap CRISPR Gene Dependency	1.0	2.60629
GSE158320,GSE183351_0_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAC3 GTPase cycle	Reactome Pathways 2024	1.0	null
GSE165682_2_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE185635_0_v_1_ncor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRDX6	Pathway Commons Protein-Protein Interactions	1.0	null
protoveratrine A-4963	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-MEL-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.23533
Parabrachial nucleus, lateral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64551
TRIM45	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_2963_KD_Nap1l2_SRP304879	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.54312
NDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18948
GSE183251_1_v_3_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5514-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6963_OE_Med13_SRP049167	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.53974
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r7 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00949
Signaling by Rho GTPases	Reactome Pathways 2024	1.0	null
tubocurarine chloride-6351	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SP4	ENCODE Transcription Factor Targets	1.0	null
PLEC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PDIA3	Pathway Commons Protein-Protein Interactions	1.0	null
HES5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04254
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEK9	Pathway Commons Protein-Protein Interactions	1.0	null
EXOSC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28697
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DUSP1_KO_GDS1606_775_mouse_Spleens	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
dexamethasone-6271	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sarcoma_SARC_TCGA-DX-A48U-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ANK2	Pathway Commons Protein-Protein Interactions	1.0	null
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.45297
intermediate stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63116
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALYREF	Pathway Commons Protein-Protein Interactions	1.0	null
Anterior olfactory nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.05936
parkinson's disease	GAD Gene-Disease Associations	1.0	null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSD17B10	Pathway Commons Protein-Protein Interactions	1.0	null
muscle	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-520c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FERMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22795
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_0_v_10_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051185
WASHC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2585
GSE201042_2_v_3_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.983597
dapsone-1868	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXA1_01_104	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.04746
PMC8166871__F7	PFOCR Pathway Figure Associations 2024	1.0	null
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
tridihexethyl-5067	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB-24764292-MC3T3-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
JUN-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
5279552-960	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.836173
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COPS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45468
GSE147876,GSE147877_2_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043832
MTPN	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_10337_KO_Camk2d_SRP281889	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.86223
GSE205163,GSE205164_2_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal lateral geniculate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39326
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SA-A6C2-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Flemming body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.697
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
cyclic adenosine monophosphate-2969	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Adenocarcinoma	CTD Gene-Disease Associations	1.0	1.18126
GSE125153_1_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NANOG-20526341-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CYP2C8	Pathway Commons Protein-Protein Interactions	1.0	null
GSE176008_0_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
LLGL1	Pathway Commons Protein-Protein Interactions	1.0	null
PYDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26057
KRT75	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Niemann-Pick disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATG3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FGF23_OE_GDS3361_493_mouse_kidney	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE158853_0_v_1_hmgcs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	41.7816
POF1B	Pathway Commons Protein-Protein Interactions	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.34114
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205316,GSE205317_0_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68567
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80151
chlorzoxazone-7456	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Seizures	CTD Gene-Disease Associations	1.0	1.17101
NACA	Pathway Commons Protein-Protein Interactions	1.0	null
YWHAB	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hydralazine-2349	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ALDH9A1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE211177,GSE211178_4_v_10_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Linear nucleus of the medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.552
NUP210	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancuronium bromide-7329	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VTN	Pathway Commons Protein-Protein Interactions	1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.3667
GSE193258,GSE193259_2_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MEST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46957
nitrendipine-3087	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YY1	ChEA Transcription Factor Targets	1.0	null
RPLP1	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A76B-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSPD1	Pathway Commons Protein-Protein Interactions	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
PMC8481886-Table_1.xlsx-A_subsets-iMSC_fetal_MSC_UC_MSC_bone_marrow_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
NUDT1	Pathway Commons Protein-Protein Interactions	1.0	null
parabrachial part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8172
muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214576
RHOD GTPase cycle	Reactome Pathways 2024	1.0	null
GSE151119_2_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
naproxen-7146	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4859-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNRPA	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_54_KD_Ago2_SRP259987	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.02848
GSE217694_3_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_9_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
C19orf73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12905
CAV1_Deficiency_GDS3551_559_mouse_Hearts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
laudanosine-7030	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
layer III of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12588
CENPE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1632
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A76L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE62843,GSE64371_2_v_5_furan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN013_HEPG2_24H:K03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0042
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
neuro2a	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.884267
GSE153137,GSE153140_2_v_0_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Amphisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.145
SENP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61165
trichostatin A-6546	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE228106_0_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.94302
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053029
HCC1419	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.84353
PABPC4	Pathway Commons Protein-Protein Interactions	1.0	null
HPRT1	Pathway Commons Protein-Protein Interactions	1.0	null
FKBP4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE116810_2_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
HIST1H2BL	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-BI-A20A-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLIN5_OE_GSE44192_482_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	3.08047
r6 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10632
scopolamine N-oxide-6335	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Tertiary granule membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
myocardium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.422292
TE-6	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.2563
GSE147943_5_v_1_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111035,GSE111040_3_v_13_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE227592_4_v_3_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.038
chr4_76299684_T_G_b38	GTEx eQTL 2025	1.0	2.7828
trichostatin A-6736	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DOCK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41912
LIN7A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.68105
GSE202434,GSE202438_4_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
outer SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.834485
COQ9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09394
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039558
GTF2I	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
nicardipine-5397	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE216538_1_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A5SL-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81969
GSE146982_4_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.31199
Perturb_15452_KD_circCSNK1G3_SRP139940	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.76136
PACS1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-WK-A8XX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118816_2_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4342-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRGQ	Pathway Commons Protein-Protein Interactions	1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.30174
ANKFY1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE199092_2_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KRT6B	Pathway Commons Protein-Protein Interactions	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-LK-A4O4-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE248858_4_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RAB7A	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN013_HEPG2_24H:I14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07422
Lewy neurite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.662
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POFUT2	Pathway Commons Protein-Protein Interactions	1.0	null
MAP1LC3B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.034
GSE213588_10_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
tretinoin-991	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RBM34	Pathway Commons Protein-Protein Interactions	1.0	null
trichostatin A-1793	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72631
GSE168797_2_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216538_7_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DU4475	DepMap CRISPR Gene Dependency	1.0	3.64421
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6772
PRKCI	Pathway Commons Protein-Protein Interactions	1.0	null
G3BP2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE205163,GSE205164_2_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17315
BMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62262
deferoxamine-485	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LETM2	Pathway Commons Protein-Protein Interactions	1.0	null
MYOG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.7547
Lung squamous cell carcinoma_LUSC_TCGA-56-8624-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12170838-41698_2025_973_MOESM1_ESM.pdf-31-RBPJ_RBPJ	Rummagene Transcription Factor Associations 2026	1.0	null
Bounding membrane of organelle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16359
MOLT16	CCLE Cell Line Gene Expression Profiles	-1.0	-1.4736
S100A11	Pathway Commons Protein-Protein Interactions	1.0	null
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8546
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12861
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.937239
ELK1	ENCODE Transcription Factor Targets	1.0	null
OV56	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01063
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08362
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A0VM-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB33B	Pathway Commons Protein-Protein Interactions	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.055
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	104.523
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.900995
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE236486_1_v_2_arnt_human	RummaGEO Gene Perturbation Signatures	1.0	null
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20067
dropropizine-2398	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.954542
Chanarin-Dorfman syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.007
Prestwick-1082-7267	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RPL11	Pathway Commons Protein-Protein Interactions	1.0	null
CHD4	Pathway Commons Protein-Protein Interactions	1.0	null
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HUH1	CCLE Cell Line Gene Expression Profiles	1.0	1.91201
TOP1	Pathway Commons Protein-Protein Interactions	1.0	null
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.33924
nucleus sagulum, deep part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63041
GSE159893_2_v_1_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22372
KMS11	CCLE Cell Line Gene Expression Profiles	1.0	2.08612
mitoxantrone-6755	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7154-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAIP2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Hypertrophy	CTD Gene-Disease Associations	1.0	1.43103
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.02486
MAFK_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:E16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.15302
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154253_1_v_0_tnfaip8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043949
TROVE2	Pathway Commons Protein-Protein Interactions	1.0	null
CP-320650-01-3908	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UTP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11912
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TFG	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128240_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE116810_2_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.828618
YTHDF2	Pathway Commons Protein-Protein Interactions	1.0	null
HDMYZ	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05905
Nausea	CTD Gene-Disease Associations	1.0	1.13793
SF3B1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Atrophy	CTD Gene-Disease Associations	1.0	1.4332
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIA1_KO_GSE54418_267_mouse_spinal cord	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
SMARCC1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE214842_0_v_1_atf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AAMP	Pathway Commons Protein-Protein Interactions	1.0	null
RPL34	Pathway Commons Protein-Protein Interactions	1.0	null
Anemia, Hemolytic	CTD Gene-Disease Associations	1.0	1.18193
DHX9	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH2066	CCLE Cell Line Gene Expression Profiles	1.0	1.37523
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27862
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE188870,GSE188871_1_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10933434-44319_2024_69_MOESM2_ESM.xls-HRV16-UV_vs_MI-Ensembl_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
GPC6	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_2114_KD_SF3B3_SRP268983	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.36634
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28999
GEMIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39549
H3K9ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.6616
MOV10	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_9498_KO_Lsd1_SRP096254	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE233679_5_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139987_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_6358_KO_NumbL_SRP307901	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.66391
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BCAS2	Pathway Commons Protein-Protein Interactions	1.0	null
NIP7	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5688
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YWHAZ	Pathway Commons Protein-Protein Interactions	1.0	null
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.32252
KARS	Pathway Commons Protein-Protein Interactions	1.0	null
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.451
Parabrachial nucleus, lateral division, central lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.36112
SEC24C	Pathway Commons Protein-Protein Interactions	1.0	null
SW1573	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40576
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE100316_7_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211128_3_v_5_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTSA	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE146072_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SLC25A3	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7914-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
epithelioma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053422
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VIM	Pathway Commons Protein-Protein Interactions	1.0	null
PMC10015223-can-22-1444_supplementary_data_2_suppsd2.xlsx-RT4-FOXA1_peaks_Context1_2-Gene_Name_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
GM2A	Pathway Commons Protein-Protein Interactions	1.0	null
MRPL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11099
hsa-miR-2682	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
liver	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070989
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HP1BP3	Pathway Commons Protein-Protein Interactions	1.0	null
RPMI8402	CCLE Cell Line Gene CNV Profiles	1.0	2.00248
GSE149903_6_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KMS26	CCLE Cell Line Gene Expression Profiles	1.0	2.25257
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSTP1	Pathway Commons Protein-Protein Interactions	1.0	null
PMC2263127-pone.0001816.s002.xls-Terms_with_Genes_E2F3_up_Bild-Title_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.862329
LRRC15	Pathway Commons Protein-Protein Interactions	1.0	null
ARHGAP11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50784
NCIH1339	CCLE Cell Line Gene CNV Profiles	1.0	1.7015
IRS4_KO_GDS1219_306_mouse_brown preadipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4222
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TP63	ChEA Transcription Factor Targets	1.0	null
REST_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRPF39	Pathway Commons Protein-Protein Interactions	1.0	null
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05201
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_HEPG2_48H:B12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.14505
TOMM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59143
CRCGN015_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.5491
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PSMF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5378
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01673
Anterolateral visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.04038
RRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05614
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04412
GSE225982_2_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66932
MSTN_KO_GDS3637_439_mouse_muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
DLST	Pathway Commons Protein-Protein Interactions	1.0	null
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE132386_2_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
caffeic acid-3053	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050745
GSE137325_2_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052449
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.867902
DMRT1-23473982-TESTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE217071_3_v_0_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8511-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:B18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28465
SNRNP27	Pathway Commons Protein-Protein Interactions	1.0	null
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.618908
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.913797
GSE214596,GSE214598_1_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
tremorine-3196	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Smad4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0
Prestwick-692-2165	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BLMH	Pathway Commons Protein-Protein Interactions	1.0	null
NRF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
doxycycline-5838	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE128333_4_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_13673_KO_Mir155_SRP057986	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.64191
MCM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08223
CL-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.32093
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
Intersegmental muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.798
PMC12238561-42003_2025_8460_MOESM2_ESM.xlsx-IDs_S12_LF_C1_8h-Unnamed_5_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE116810_5_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
Left ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.078
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE95077_5_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
EIF6	Pathway Commons Protein-Protein Interactions	1.0	null
TIS granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.599
esr1_21299862_mcf7_lof_human_gpl570_gds4065	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.744777
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.10788
PMC8507136-12935_2021_2224_MOESM5_ESM.xlsx-CREB1_upregulated_RRHO_list-RRHO_concordant_degree_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
TRIM21	Pathway Commons Protein-Protein Interactions	1.0	null
HSP90AA1	Pathway Commons Protein-Protein Interactions	1.0	null
SACS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36312
GET4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27321
NUDT16L1	Pathway Commons Protein-Protein Interactions	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.49225
CRCGN017_MCF10A.TP53.M_24H:J04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03903
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Peripheral_Blood_Mononuclear_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.842873
GSE226091,GSE226092_3_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125007,GSE125008_4_v_0_uhrf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Immunoglobulin-like fold	InterPro Predicted Protein Domain Annotations	1.0	null
CRCGN015_HEPG2_48H:C01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45797
Lung adenocarcinoma_LUAD_TCGA-55-7994-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
SON	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80826
TCCSUP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TPI1	Pathway Commons Protein-Protein Interactions	1.0	null
EP300-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Secretory granule	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Inclusion Body Myositides_Muscle tissue_GSE3112	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.70141
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tertiary granule membrane	GO Cellular Component Annotations 2023	1.0	null
GSE84678,GSE93902_3_v_2_bcl11b_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34694
PSPC1	Pathway Commons Protein-Protein Interactions	1.0	null
Hepatobiliary benign neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.058
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-5_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
SPTBN1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE223241_2_v_0_cdkn2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.TP53.M_24H:E07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34702
TUHR14TKB	CCLE Cell Line Gene CNV Profiles	1.0	1.48621
Perturb_6332_KO_Lonp1_SRP304502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.2299
ARIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58828
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
hexestrol-6252	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MPP2	Pathway Commons Protein-Protein Interactions	1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8045_KD_ST18_SRP062868	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.03209
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANXA2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE235682_3_v_0_rbl2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
r6 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34213
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01218
muscular system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SW 1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0695
BCL2L2-PABPN1	Pathway Commons Protein-Protein Interactions	1.0	null
intermediate stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00239
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24575
PSME3	Pathway Commons Protein-Protein Interactions	1.0	null
resveratrol-2865	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE202434,GSE202438_3_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RCBTB1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE162688_1_v_2_pink1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.26865
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0921
BNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61028
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_10_v_12_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.36533
intermediate stratum of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.81866
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6904118-NIHMS1544763-supplement-5.xlsx-MYB_Individual-MYB_sgRNA-9_MYB	Rummagene Transcription Factor Associations 2026	1.0	null
Urinary Bladder Diseases	CTD Gene-Disease Associations	1.0	1.10838
MIF	Pathway Commons Protein-Protein Interactions	1.0	null
GSE77108_3_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTF2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2398
bepridil-1274	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11724
FAU	Pathway Commons Protein-Protein Interactions	1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
cycloserine-7134	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_6342_KO_LONP1/ATF4_SRP353442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
NCI-H446	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE48812_4_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
trichostatin A-1014	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
IGHM	Pathway Commons Protein-Protein Interactions	1.0	null
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.18651
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCAD_KO_GDS4546_422_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.790617
CRCGN015_MCF10A.TP53.M_24H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5261
NOL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2754
hepatoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06292
DAP3	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_10909_KD_Eif3m_SRP157047	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.06711
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE193402_0_v_4_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01491
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A196-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS294T	DepMap CRISPR Gene Dependency	1.0	3.14538
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19417
GSE203308_1_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tonzonium bromide-3080	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35237
NCIH2066	CCLE Cell Line Gene CNV Profiles	1.0	1.65968
PPP3CB	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4837-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4338-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Parabrachial nucleus, lateral division, ventral lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18293
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PLOD3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE199606_1_v_0_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
dexamethasone_rattus norvegicus_gpl1355_gse29912	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE155031_5_v_1_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Parkinson's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.926293
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPLP0	Pathway Commons Protein-Protein Interactions	1.0	null
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_6344_KO_Ppargc1a3_SRP375932	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.078
estradiol-5318	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EEF1B2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE210476_2_v_7_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Endometriosis_Endometrium_GSE7305	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.76225
membrane part	GO Cellular Component Annotations 2015	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052957
PMC10363146-41598_2023_38681_MOESM1_ESM.pdf-507-ETV3L_ETV3L	Rummagene Transcription Factor Associations 2026	1.0	null
H2BK20ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB436	DepMap CRISPR Gene Dependency	1.0	2.37045
GSE123836_2_v_3_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Signaling by Rho GTPases, Miro GTPases and RHOBTB3	Reactome Pathways 2024	1.0	null
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.95415
Muscle thin filament tropomyosin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.937
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.96414
Prestwick-559-7462	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
C12orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4751
Brain Lower Grade Glioma_LGG_TCGA-P5-A5EU-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RSL1D1	Pathway Commons Protein-Protein Interactions	1.0	null
secretory granule membrane	GO Cellular Component Annotations 2025	1.0	null
sirolimus_mus musculus_gpl1261_gse21755	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CCT4	Pathway Commons Protein-Protein Interactions	1.0	null
GSE226316_3_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111385_2_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44731
Sarcoma_SARC_TCGA-PC-A5DL-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_6341_KO_LONP1_SRP353442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
CRCGN011_HEPG2_24H:P07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3613
GAR1	Pathway Commons Protein-Protein Interactions	1.0	null
ZBTB7A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8073
PMC7773934-Table_1.XLSX-Table_S2-Supplementary_Table_2_TBX22_co-expressed_genes_detailed_results_TBX22	Rummagene Transcription Factor Associations 2026	1.0	null
PMC6754502-41598_2019_50051_MOESM3_ESM.xlsx-Br_to_Fay_Heat_LPS-Gene_Symbol_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
isoniazid-7197	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
1320_CCND1_P1	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.12512
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Extensor digitorum longus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.734
KRT13	Pathway Commons Protein-Protein Interactions	1.0	null
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.862915
phentolamine-1138	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.051512
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE136894_2_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Paralysis	CTD Gene-Disease Associations	1.0	1.04868
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
PDHB	Pathway Commons Protein-Protein Interactions	1.0	null
PMC11330984-41467_2024_51229_MOESM6_ESM.xlsx-MYC_UP-ID_SYMBOL_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-548p	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
RPS2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE215849_2_v_1_muc1_human	RummaGEO Gene Perturbation Signatures	1.0	null
cos cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.323144
FBXO41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06516
Parkinson's disease 15	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15671
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.00332
bupivacaine-7435	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TMC1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SNRPC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE206870,GSE206872_4_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NOSIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57672
TUBGCP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10734
GSE207301,GSE207303_1_v_3_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
strophanthidin-5826	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MRPL43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24203
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TV-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-8120-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.WT.HP_24H:G06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.3398
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51867
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13488
NOL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06877
TSR2	Pathway Commons Protein-Protein Interactions	1.0	null
U2AF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0955
GSE147366_1_v_4_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.86286
CRCGN015_MCF10A_48H:O07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13156
YY1_KO_GSE39009_49_mouse_skeletal muscle (6 mo)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Perturb_11467_KD_SRSF1_SRP290964	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9218734-Supplementary_Data3.xlsx-KRIEG-KRIEG_HYPOXIA_NOT_VIA_KDM3A_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
YLPM1	Pathway Commons Protein-Protein Interactions	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
Lung squamous cell carcinoma_LUSC_TCGA-37-4130-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PWP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE231720,GSE231724_2_v_0_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202744_1_v_0_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
glycogen binding	GO Molecular Function Annotations 2025	1.0	null
AHSA1	Pathway Commons Protein-Protein Interactions	1.0	null
adult retina	HPM Cell Type and Tissue Protein Expression Profiles	-1.0	-0.974419
lower dorsal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21086
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cdx2_20696899_caco2_lof_human_gpl570_gse22572	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.541069
CRCGN010_HEPG2_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.77922
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.310059
ATPSCKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8857
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
lateral mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.90665
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62541
Perturb_13064_KO_Bak/Bax_SRP055036	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE207433_0_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE261563_3_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
EWSR1	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.24645
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10769395-media-2.xlsx-S2D_EF_Repressed_genes-Ebegboni_et_al_Supplemental_Table_S2D_Increased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GMPPA	Pathway Commons Protein-Protein Interactions	1.0	null
GSE173911,GSE173917_0_v_1_morc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24277
ethaverine-3037	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WDFY3	Pathway Commons Protein-Protein Interactions	1.0	null
pyramidal layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16615
H4K20me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
tanespimycin-6185	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ADGRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65428
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VU-01A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DHX57	Pathway Commons Protein-Protein Interactions	1.0	null
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.63452
UMC-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.51867
SRRM2	Pathway Commons Protein-Protein Interactions	1.0	null
PPA1	Pathway Commons Protein-Protein Interactions	1.0	null
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87307
Gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r4 part of pontine raphe cell population	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24833
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.204223
cytoplasm	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
motif	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-106a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
TGM3	Pathway Commons Protein-Protein Interactions	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4T-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.40302
XRCC5	Pathway Commons Protein-Protein Interactions	1.0	null
FTSJ3	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_5861_KD_H3f3a_SRP133189	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.91732
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A6RX-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cytosol	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.895
PMC3255547-supp_007401_DMM007401TableS6.xls-EWS-FLI1_signatures-Unnamed_4_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_9701_KD_RTN4R_SRP368642	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.0526
RPL6	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A8AZ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DPYSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78766
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
CBLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3936
CTSD	Pathway Commons Protein-Protein Interactions	1.0	null
SPTAN1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08858
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.825252
carbohydrate binding	GO Molecular Function Annotations 2015	1.0	null
NCI-H2110	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.58954
stbd1	GeneRIF Biological Term Annotations	1.0	null
RAD21_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158456_2_v_3_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM169	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88272
uterus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Locus ceruleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1102
C3orf14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43708
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11598
GSE149903_6_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10175
trichostatin A-4565	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prestwick-689-5816	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SPTSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98175
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169205_0_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4306
glycogen catabolic process	GO Biological Process Annotations 2023	1.0	null
Epithalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51192
Neoplasm Metastasis	CTD Gene-Disease Associations	1.0	1.14132
GFAP	Pathway Commons Protein-Protein Interactions	1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.6144
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1AC-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
midecamycin-1943	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.987248
ABCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03036
SW1990	DepMap CRISPR Gene Dependency	1.0	2.43173
CDSN	Pathway Commons Protein-Protein Interactions	1.0	null
15486232-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	122.5
Fatty Liver	CTD Gene-Disease Associations	1.0	1.75719
intermediate stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7465
CRCGN016_MCF10A.WT.HP_24H:D19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.40396
OCT1-27270436-CHIP-SEQ-PROSTATE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23039
RBM28	Pathway Commons Protein-Protein Interactions	1.0	null
GSE95685_4_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE88819_5_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE161302,GSE161304_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Accessory facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11528
IGHG2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6849
Adrenocortical carcinoma_ACC_TCGA-OR-A5KU-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998961
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
superficial stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39842
mantle zone of the PBC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66858
Lung adenocarcinoma_LUAD_TCGA-49-4488-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.998961
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_12_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HSPA5	Pathway Commons Protein-Protein Interactions	1.0	null
GSE100316_3_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100425_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.52602
Perturb_7768_KD_EXOC5_DRP001280	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.21093
Obesity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
GSE237040_4_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
STRAP	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-134	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.882116
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r1 part of the 'mesencephalic' trigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.09207
ionomycin-871	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hesperetin-5350	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6UA-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
decreased prepulse inhibition	IMPC Knockout Mouse Phenotypes	1.0	null
Perturb_8706_KD_SIRT1_SRP267968	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.19864
PI4K2A	Pathway Commons Protein-Protein Interactions	1.0	null
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	101.737
dorsal peduncular cortex, periventricular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49731
Perturb_11907_OE_Tlr7_SRP155370	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.81411
GSE248858_5_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
layer 2 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20296
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN011_HEPG2_24H:G07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1415
Perturb_8058_KD_IGF2BP1_SRP094100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.632
hsa-miR-548ab	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Phagophore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.688
CRCGN008_HEPG2_24H:H15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0184
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.860043
ETV5::HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7788
GSE229973_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
suxibuzone-2503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111035,GSE111040_8_v_5_plag1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NECAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55413
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055444
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	89.532
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12161
GSE153871_5_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PSMB7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62805
Superior colliculus, superficial gray layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50903
PRPH	Pathway Commons Protein-Protein Interactions	1.0	null
CD2BP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05184
Parkinson Disease	DisGeNET Gene-Disease Associations	1.0	null
articaine-7272	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PRDX2	Pathway Commons Protein-Protein Interactions	1.0	null
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31994
pralidoxime-6283	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
NOC3L	Pathway Commons Protein-Protein Interactions	1.0	null
SKNO1	CCLE Cell Line Gene CNV Profiles	1.0	1.40738
WM1552C	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.64504
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.147
Perturb_15418_OE_KDM4B_SRP194543	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.21214
LMNA	Pathway Commons Protein-Protein Interactions	1.0	null
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211128_7_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Fibrosis	CTD Gene-Disease Associations	1.0	1.91635
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6868_OE_STBD1_SRP316253	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
SEC61B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16272
TP53INP2_KO_GSE54917_384_mouse_Quadriceps muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
hsa-miR-4662a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ticlopidine-1975	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-374b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bufexamac-2382	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.76198
hsa-miR-509-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GSE214212_2_v_1_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158431_5_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13853
haloperidol-1185	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PLOD1	Pathway Commons Protein-Protein Interactions	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03783
CRCGN015_MCF10A.TP53.M_24H:E17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5344
PMC2966110__F8	PFOCR Pathway Figure Associations 2023	1.0	null
GSE160373_6_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04501
L428	CCLE Cell Line Gene Expression Profiles	-1.0	-1.88414
RPL4	Pathway Commons Protein-Protein Interactions	1.0	null
SNU-475	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.98733
PMC6126969-NIHMS979612-supplement-7.xlsx-Tab_5_TbID_-biotin_ERM_proteo-Gene_Name_ETV5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150669_0_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_13523_KD_Arid1a_SRP333303	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.5086
TBP	ENCODE Transcription Factor Targets	1.0	null
Perturb_14952_OE_Tnfsf14_SRP148550	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5971-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HIST1H2AB	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_14834_KD_Scr_SRP017110	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.7521
ZNF143	ENCODE Transcription Factor Targets	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.68
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RHOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06149
TUHR10TKB	CCLE Cell Line Gene Expression Profiles	1.0	1.46692
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PYGL	Pathway Commons Protein-Protein Interactions	1.0	null
vertebrate muscular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.45374
GATA2-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.56815
GSE201309_4_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.90258
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SKMG1	DepMap CRISPR Gene Dependency	1.0	3.01149
GSE147876,GSE147877_4_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3VY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Retinitis pigmentosa 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.32
GSE101336_1_v_2_decitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00895
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
VDAC2	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_14693_KO_Sufu/Spop_SRP171166	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-19.301
DPF2	Pathway Commons Protein-Protein Interactions	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
DDX21	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03015
vacuole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.313718
17210682-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
RPL12	Pathway Commons Protein-Protein Interactions	1.0	null
CADM1_KO_GDS2026_301_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nurse cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.632
late endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.239197
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01404
BMI1-23680149-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Parabrachial nucleus, lateral division, superior lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37063
Perturb_13115_KO_Foxm1_SRP194062	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.06907
metronidazole-1503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Acute Myeloid Leukemia_LAML_TCGA-AB-2898-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cefmetazole-7222	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9035581-HEP4-6-1157-s002.docx-3-Supplementary_Table_S5_Gene_expression_signature_of_endogenous_FOXS1_silencing_in_SNU-449_cells_FOXS1	Rummagene Transcription Factor Associations 2026	1.0	null
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36617
RRP1	Pathway Commons Protein-Protein Interactions	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ticarcillin-6146	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-L9-A443-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oxprenolol-6145	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_K27me3_17603471_mouseNPC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TB-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.968609
Perturb_4351_OE_Sall1_SRP409197	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.4857
proadifen-2707	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.950396
BMI1-23680149-NPCS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CSPG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15309
COA6	Pathway Commons Protein-Protein Interactions	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Psoas_Muscle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.15955
Sarcolemma	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
496100368_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.71539
t56-vastus-lateralis_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	4.18711
MAZ_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.76357
GSE146074_0_v_7_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
deptropine-5543	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ADPRM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68432
HAUS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48106
RFC2	Pathway Commons Protein-Protein Interactions	1.0	null
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149355_0_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
haloperidol-983	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hypertension	CTD Gene-Disease Associations	1.0	1.53531
TUBG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39878
HS578T	CCLE Cell Line Gene Expression Profiles	1.0	1.60285
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-2.22522
RPTN	Pathway Commons Protein-Protein Interactions	1.0	null
tridihexethyl-2964	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.18915
dorsolateral preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32566
293-F FreeStyle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
RAD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6474
hsa-miR-136	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0664
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
secretory granule membrane	GO Cellular Component Annotations 2023	1.0	null
GSE169152_5_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
talampicillin-2954	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SMARCA4	Pathway Commons Protein-Protein Interactions	1.0	null
PMC2263127-pone.0001816.s001.xls-E2F3_up_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
EPRS	Pathway Commons Protein-Protein Interactions	1.0	null
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ADPRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63399
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SERPINB3	Pathway Commons Protein-Protein Interactions	1.0	null
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	75.899
amitriptyline-6353	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
system process	GO Biological Process Annotations 2015	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158632_3_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Jaundice	CTD Gene-Disease Associations	1.0	1.01474
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KRT5	Pathway Commons Protein-Protein Interactions	1.0	null
bethanechol-2975	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
decreased prepulse inhibition	MGI Mouse Phenotype Associations 2023	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JT-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NIX_Deficiency_GDS2630_160_mouse_spleen	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
FASN	Pathway Commons Protein-Protein Interactions	1.0	null
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2463
cSARS Bat SRBD_12Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.7122
CCNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90825
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12767
TMED10	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-520e	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221633_3_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4377
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heart muscle	HPA Tissue Protein Expression Profiles	1.0	1.00184
GSE217552_3_v_2_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CSTB	Pathway Commons Protein-Protein Interactions	1.0	null
KCNH2	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN009_HEPG2_24H:D11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.3898
CSRP2	Pathway Commons Protein-Protein Interactions	1.0	null