association	dataset	threshold value	standardized value
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Azacitidine_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0195128
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.42731
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77193
Taenia tecta, ventral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06584
CRCGN014_HEPG2_24H:H24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.234
GTEX-S7SF-0526-SM-3K2BC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895009
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29X-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
RERFLCAD1	CCLE Cell Line Gene CNV Profiles	1.0	1.64831
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K08881846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09994
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.948402
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22913
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-0002-SM-4AT5O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89684
protein serine/threonine kinase activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
GSE142684_0_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_4_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12660_KD_NFE2L2_SRP242008	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
XCL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00538124
MEL-JUSO	GDSC Cell Line Gene Expression Profiles	1.0	1.46446
GSE236437_2_v_3_aldosterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7371-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE144115_4_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE173873_1_v_3_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Andarine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134054
SLC35E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25008
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-UJHI-0426-SM-3DB8Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914829
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.43544
protein metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039305
Kinocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.044
GTEX-T6MN-1126-SM-4DM71	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835367
Sarcoma_SARC_TCGA-IE-A4EJ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-3.35055
Spondyloepimetaphyseal dysplasia with joint laxity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.58
BRD-K20853228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02013
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.566616
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23232
BRD-K23203419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93191
PC14	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58109
PDXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05865
A549_XAV-939_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0366587
brain disease	GWASdb SNP-Disease Associations	1.0	0.154217
A549_Pracinostat_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167463
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.772358
BRD-K97527915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57518
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57866
GSE226249_2_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Alzheimer's disease (cognitive decline)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.630103
A549_Motesanib Diphosphate_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126786
BRD-K72531838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04094
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.59392
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K88224221	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34179
PMC4791243-oncotarget-06-43452-s006.xlsx-Supplementary_table_S5-Supplementary_table_S5_Differentially_expressed_genes_in_TP53_mutant_versus_TP53_wild_type_cell_lines_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE214823,GSE214824_5_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_8_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LN340	DepMap CRISPR Gene Dependency	1.0	14.1566
MTAP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00459453
WM88	CCLE Cell Line Gene Mutation Profiles	1.0	null
BRD-K02473319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04664
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K82019575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02889
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.976919
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transferase activity	GO Molecular Function Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164874_5_v_8_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K75206048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27331
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormal eye physiology	GWASdb SNP-Phenotype Associations	1.0	0.208064
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K90047132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22472
A549_Panobinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0120639
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16949
ELF1	ENCODE Transcription Factor Targets	1.0	null
sarcoidosis	GWASdb SNP-Disease Associations	1.0	0.609395
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43479
Coronary Artery Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K68544484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65826
BRD-K52223190	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10786
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13I-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228106_0_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K22875065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35857
BRD-K78315404	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54472
hsa-miR-10a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39934
hsa-miR-4477a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
A549_Baricitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0213245
CRCGN011_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0302
A549_Regorafenib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165224
GLRX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35332
mantle zone of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26051
TRAF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00516158
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.981874
outer CP in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.992932
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
KDM6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18232
abnormality of leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.092178
NCI-H2122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.856169
BRD-K17384993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33344
BRD-K75625428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32942
GTEX-WFON-2326-SM-3LK7M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854572
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-654-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-XQ8I-0526-SM-4BOPS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12039
ventrolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.75537
H3K27me3_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sensory disturbances after bilateral sagittal split ramus osteotomy	GWAS Catalog SNP-Phenotype Associations	1.0	0.057619
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.898124
Brain Lower Grade Glioma_LGG_TCGA-FG-5963-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38633800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55256
GTEX-VUSG-2226-SM-4KKZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16093
BRD-K90741031	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35122
GSE213588_10_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE179974_3_v_5_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66394
BRD-K40560569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09477
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
A549_M344_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147493
GSE168797_2_v_0_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11477
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4686761-ncomms10068-s3.xlsx-S2D-NSC_down_overlap-Supplementary_Data_2D_-_expression_of_genes_in_NSC_down-regulated_2_fold_change_in_both_MSC_PTEN-_-_vs_MSC_PTEN_and_NSC_PTEN-_-_vs_NSC_PTEN_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10769314-NIHMS1954782-supplement-9.xlsx-Table_S7B-Table_S7B_Frontal_cortex_relative_gene_expression_from_post-KD_and_pre-KD_recipient_mice_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_6251_KO_Dicer_SRP041835	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866801
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A69E-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PX3G-0826-SM-48TZS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94246
Perturb_424_KD_EHF_SRP049988	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
disease of mental health	GWASdb SNP-Disease Associations	1.0	0.237247
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
BRD-K87669186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.24833
reticular formation of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36839
GSE128563_2_v_6_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
km3	HPA Cell Line Gene Expression Profiles	1.0	1.0357
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A55W-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Age at suicide	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.61549
GTEX-U3ZN-1426-SM-3DB87	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00885
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0538
ALAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14099
PMC10721704-12265_2022_10347_MOESM9_ESM.xlsx-S6A-Supplementary_Table_6A_Region_level_burden_tests_variants_with_MAF_0_05_only_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.44448
BRD-A16313205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0907
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Climbing fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.663
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-S_48h_1-Unnamed_0_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
20032505-TableS6	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-423-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Azacitidine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165151
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6599263-13073_2019_654_MOESM2_ESM.xlsx-CAR1_tsv-gene_name_NR1I3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
DNALI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05625
STYX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44955
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0116
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01916
VZ in postamygdaloid region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.85787
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_POU5F1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K52552873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.99482
orbital frontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45551
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE133213_6_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A95442017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09687
GSE171486_4_v_6_ddx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039261
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9314667-Table_1.xlsx-Regulons-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888553
GSE140322_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
2-BFI	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07355
A549_Costunolide_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176157
UMRC2	CCLE Cell Line Gene Expression Profiles	1.0	1.8781
GTEX-TKQ1-0003-SM-3NMAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13627
BRD-K47271260	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75252
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07168
SRC_activemutant_51_GSE15815	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.85371
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-A61V-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.946565
H3K9ac_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_SRT3025 HCl_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0218667
carbohydrate derivative binding	GO Molecular Function Annotations 2015	1.0	null
Perturb_14686_KO_Sirt3_SRP277814	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.75681
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, mouth, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5822
kidney_c	HPA Tissue Sample Gene Expression Profiles	1.0	1.30578
Sima	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.524
ARHGAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22355
LIVF001-018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39023
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10529
HCC78	DepMap CRISPR Gene Dependency	1.0	3.33345
phosphate-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K58643762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00899
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.20749
GTEX-WRHU-0326-SM-3MJFY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84333
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28196
H3K36me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
supranuclear gaze palsy	GWASdb SNP-Phenotype Associations	1.0	0.556012
GSE211989_3_v_2_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162892_3_v_1_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-REY6-0326-SM-2TF5A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831475
WM-115	GDSC Cell Line Gene Expression Profiles	1.0	1.73269
BRD-K42061172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02817
Celiac disease	GWAS Catalog SNP-Phenotype Associations	1.0	0.048624
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12399715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22889
BRD-K31269097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27427
cuneus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.50142
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K26231789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04893
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12933612-mmc2.xlsx-eTable_14_Gene_sets-MULLIGHAN_MLL_SIGNATURE_2_DN_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
ORM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00559683
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.24423
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.209317
BRD-K07939054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22805
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.91754
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66394
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.961218
GTEX-P44H-0326-SM-2XCES	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32075
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sensory neuropathy	GWASdb SNP-Phenotype Associations	1.0	0.40409
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13845
Ar	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7175
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64711
nucleus of the diagonal band, left, vertical division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.07254
GSE95077_1_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_375_KD_DHX16_SRP309315	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.8594
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6024-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05934
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_48h_2-down-regulated_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
schizophrenia	GWASdb SNP-Phenotype Associations	1.0	0.713239
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE142684_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66949
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
perifornical nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1234
p1 part of the substantia nigra reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4804
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11547
GTEX-WHPG-0004-SM-3NMDO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94263
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-Gene_SymbolH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
DSCAML1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00551463
A549_Barasertib_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015723
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46274
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46819
GTEX-S95S-0002-SM-3NM8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.999784
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855656
r3 part of spinal trigeminal sensory column, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.291
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.1598
synucleinopathy	GWASdb SNP-Disease Associations	1.0	0.572462
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0572
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
B4GALT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00609657
BRD-K03624299	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15284
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3828
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
HSF1_KD_GDS1733_754_human_HeLa cells -  0 Hour by siHSF1_2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10987
H3K4me1_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8251
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00869
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE161864,GSE161866_0_v_2_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22546
BRD-K50271780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53349
GSE86507,GSE86509_3_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825806
hsa-miR-4690-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GSE126345_0_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04832
eye and adnexa disease	GWASdb SNP-Disease Associations	1.0	0.143094
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11368
BRD-K60828476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33336
Setleis syndrome_Skin fibroblast_GSE16524	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-0.733631
CTCF	ENCODE Transcription Factor Targets	1.0	null
BRD-K01922054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.30646
BRD-K26766324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65166
superficial stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08593
GTEX-XGQ4-0326-SM-4GIEE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37069
AGS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41495
GSE202434,GSE202438_8_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K89687419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50169
PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_6258_KO_CIC_ERP108370	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.663004
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-0004-SM-46MWA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31599
GSE182680,GSE182683_10_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K67090705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00051
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_up-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.986325
BRD-K66823946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24451
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K05417183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89638
BRD-K35909757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22668
CAPAN1	DepMap CRISPR Gene Dependency	1.0	2.10685
A549_MK-5108_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0233009
Prostate adenocarcinoma_PRAD_TCGA-J9-A52C-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050753
BRD-K17420784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06058
MJ	DepMap CRISPR Gene Dependency	1.0	2.08549
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14717
RPMI8226	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59326
GTEX-SJXC-1226-SM-4DM78	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88481
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RXF393	BioGPS Cell Line Gene Expression Profiles	1.0	0.857093
H3K9ac_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TUBB2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00712998
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8410-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61706
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_Roxadustat_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139975
GTEX-PWCY-0226-SM-48TD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09366
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20W-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152441,GSE152442_1_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K87447060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16859
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87E-01A-31R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-518a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
cleft lip	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.780251
BRD-K83122599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15359
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain_CT2_Splat 428	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
GTEX-WCDI-0002-SM-3P61U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38444
BRD-K44139185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52234
CTCF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10639
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18675
hsa-miR-1205	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55972185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97617
BRD-K48294384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15513
Electrocardiography	dbGAP Gene-Trait Associations	1.0	0.406869
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64255
PMC11839389-PUL2-15-e70058-s003.xlsx-FLF_TBX4_mergeRNAseqChIPseq-symbol_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4686761-ncomms10068-s3.xlsx-S2H-MSC_down_overlap-Supplementary_Data_2H_-_expression_of_genes_in_MSCs_which_were_down-regulated_in_both_MSC_PTEN-_-_vs_MSC_PTEN_and_NSC_PTEN-_-_vs_NSC_PTEN_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-POYW-0726-SM-2XCEO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71588
PIK3C2G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00476264
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K44803159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58893
GSE166914_1_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NUTM2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00762605
GSE119978,GSE180930_6_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SNU-475	GDSC Cell Line Gene Expression Profiles	1.0	1.42105
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K39348592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4706
inner SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16633
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158743_1_v_2_nfkbia_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WHSC1	ENCODE Transcription Factor Targets	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PIK3CD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0060691
BRD-K83270677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06022
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1482	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.13416
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4897-01A-03R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7477-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
20032505-TableS5	GeneSigDB Published Gene Signatures	1.0	null
outer SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.942489
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2M2-01A-21R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-POMQ-0126-SM-48TD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839859
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
KNS42	DepMap CRISPR Gene Dependency	1.0	2.35749
A549_ENMD-2076 L-Tartaric acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0235942
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Z8-1726-SM-3K2AX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842059
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K26760349_HG-9-91-01_PC3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88I-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67925
BRD-K46376359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38669
liver	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
Lung squamous cell carcinoma_LUSC_TCGA-66-2795-01A-02R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K50129495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12892
BRD-A25993094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39044
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Subthalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05433
superficial stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40822
TP63	ChEA Transcription Factor Targets	1.0	null
BRD-K00218068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57522
BRD-K84518331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51779
GTEX-QDT8-1326-SM-48TYY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827173
CRCGN014_HEPG2_3H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23095
A549_Amisulpride_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154454
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K98225007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37911
DCLK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0048644
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50928
Perturb_8668_KD_CSL_SRP115628	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CTCF_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular protein modification process	GO Biological Process Annotations 2015	1.0	null
BRD-K69744558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43262
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A7EU-01A-22R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01096898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11433
TTC7A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00555219
BRD-K69294714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44564
BRD-K43414987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17369
GABPA	ENCODE Transcription Factor Targets	1.0	null
GSE48812_7_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45037973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66625
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_13186_Mut_Cry2_SRP303502	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	18.0915
JUND-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE197117_0_v_1_kdm6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-637	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
borderline	GeneRIF Biological Term Annotations	1.0	null
Perturb_17738_KO_Phf8_SRP093797	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.1853
PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18629
496100374_HIP_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.43865
PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885246
18593951-TableS2	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
kidney	HPA Tissue Gene Expression Profiles	1.0	1.73929
TAF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42552
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3619-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16129
E2F6	ENCODE Transcription Factor Targets	1.0	null
nucleoside phosphate binding	GO Molecular Function Annotations 2015	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84341
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LDB1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PF-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_14241_KO_Tet1_SRP237910	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.31298
16729877-GeneTable	GeneSigDB Published Gene Signatures	1.0	null
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31939603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44143
CRCGN016_MCF10A.TP53.M_24H:H19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05961
GSE261563_6_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_BMS-754807_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130029
CCNT2	ENCODE Transcription Factor Targets	1.0	null
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10502
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spleen	HPA Tissue Gene Expression Profiles	-1.0	-1.13362
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4166-01A-02R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24886
mhhnb11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.027
GSE230744,GSE237803_0_v_3_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.46058
CTCF_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49282125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56125
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38417094	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36278
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K27618188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94675
GSE203181_0_v_1_phosphoramidon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34813
Supplemental somatosensory area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27253
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.46922
Lung squamous cell carcinoma_LUSC_TCGA-22-5473-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE173282_1_v_0_marchf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33888
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K26217579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94769
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146982_0_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0326-SM-48U1O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16337
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02163
IRF2_01_100	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.72476
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Lomustine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0176193
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
GSE223893_1_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.075168
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_3_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NB4	CCLE Cell Line Gene CNV Profiles	1.0	1.34351
CHUK_knockdown_108_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.87973
17597811-SuppTable6	GeneSigDB Published Gene Signatures	1.0	null
CRCGN013_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.50063
PMC12661646-dmm-18-052290-TableS8.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VJYA-1326-SM-3GIJC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32589
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82541
Semicircular canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
Perturb_572_KO_Plod1_SRP321648	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.2181
Lung adenocarcinoma_LUAD_TCGA-95-7562-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92929998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.28731
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	1.66326
GTEX-T5JW-1526-SM-4DM5E	GTEx Tissue Sample Gene Expression Profiles	1.0	3.87569
GTEX-U412-0526-SM-3DB9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60373
BRD-K05104363_HY-50295_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PSDG-0926-SM-2I5FP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06928
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Triamcinolone Acetonide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0110441
GTEX-X4EP-0326-SM-3P5Z6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45423
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE261563_5_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
KYSE-510	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38301
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03211
GSE148514_0_v_1_rreb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S33H-0326-SM-4AD6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22493
GTEX-WOFL-0126-SM-3MJG2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06425
HCC2279	CCLE Cell Line Gene CNV Profiles	1.0	1.41021
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6960-01A-41R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11289
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.650285
GSE148657_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A40010674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39767
Ellis-Van Creveld syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.35
GSE152441,GSE152442_0_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.15685
CRCGN015_HEPG2_48H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.41602
JADE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0538
Lung squamous cell carcinoma_LUSC_TCGA-34-2596-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSF1_KD_GDS1733_755_human_HeLa cells - 0.5 Hour by siHSF1_2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE130864_0_v_1_tincr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r6 part of ventral gigangocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-4.10739
15220918-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
GSE217694_4_v_0_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCO2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67109
immune system disease	GWASdb SNP-Disease Associations	1.0	0.101263
lateral hypothalamic area, mammillary region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2051
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04092807	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.91041
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.89399
CRCGN011_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.42865
testis_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.22538
A549_Dasatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0181627
GSE233647_2_v_3_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_7667_KD_IMP2_DRP003316	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.76151
NO-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-A37780065_TRIAMCINOLONE_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
posterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35451
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG7-1326-SM-4LMK1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26008
BRD-K62310379_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A71V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26601
GSE196671_6_v_8_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HHV8_72Hour-LEC_20080955_GSE16354	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.13703
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.5022
HADH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07101
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LEO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04425
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.961003
BRD-K46005840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36095
GSE189653,GSE203344_4_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226249_5_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K80381603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39725
FADU	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53145
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02241673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.49904
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.4137
BRD-K25600773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22848
superior colliculus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.68806
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19047
Liver hepatocellular carcinoma_LIHC_TCGA-LG-A9QC-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S7SE-0226-SM-2XCD4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879704
GSE146982_0_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
pc3	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
BRD-K08219814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14368
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Selisistat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152665
MUTZ5	CCLE Cell Line Gene Expression Profiles	1.0	2.73428
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054916
mantle zone of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10327
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K94385157	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34577
hsa-miR-3662	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
MDA-MB-330	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.11641
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K07794261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33509
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.55671
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00711
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29834
primary visual cortex (striate cortex, area V1/17)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0855
GSE169152_3_v_2_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14349
BRD-K23793049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18571
A549_Hesperadin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0125655
lip	GeneRIF Biological Term Annotations	1.0	null
GM12878	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.931907
H2BK20ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22534
GTEX-S32W-1926-SM-4AD63	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27517
hsa-miR-4795-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CRCGN016_MCF10A.TP53.M_24H:H23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05517
GTEX-V1D1-0526-SM-4JBGW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948343
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138841_0_v_1_trim6_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.493
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2542
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.57963
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PMC4580636-pone.0138782.s005.xls-Sheet1-Table_S3_List_of_Genes_with_RUNX1_binding_sites_in_each_Cytogenetic_Group_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.56001
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24139
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
SMC3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11058
Nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62113
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.928483
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06823
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_Celecoxib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0290713
GSE93674_2_v_3_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0676
A549_Valproic acid sodium salt_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0186088
SJRH30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-27b	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
A549_Trametinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145134
GTEX-TMMY-1626-SM-4DXTY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26408
Perturb_552_KD_EWSR1/EWSR1FLI1_SRP273158	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	18.5229
Ltk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.274
GTEX-RN64-0326-SM-2TC5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847652
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
peptidyl-serine phosphorylation	GO Biological Process Annotations 2023	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_0_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
GTEX-XQ8I-0226-SM-4BOPM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07012
BRD-K39476596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65021
Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A96007399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08642
GSE242083,GSE242098_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	1.34738
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19489
abnormality of the immune system	GWASdb SNP-Phenotype Associations	1.0	0.097551
HCFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02409
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17531
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_MK-5108_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0242155
temporotympanic muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19625
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE118077_7_v_2_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NDUFC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00487409
BRD-K07486034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47296
16491124-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GSE140997_2_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SF539	BioGPS Cell Line Gene Expression Profiles	1.0	0.915343
KLHL5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00492559
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K27354087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00087
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75103
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875387
BRD-K80858297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82133
RL952	CCLE Cell Line Gene Mutation Profiles	1.0	null
GTEX-XGQ4-0004-SM-4AT5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.933489
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973634
hsa-miR-154	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.947271
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
A549_Tofacitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0188475
Placental abruption	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.013
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88293
GTEX-R55G-0226-SM-48FEI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969434
GTEX-Q734-1826-SM-2I3EL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948224
Acute Myeloid Leukemia_LAML_TCGA-AB-2822-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11234
JHH6	CCLE Cell Line Gene Expression Profiles	1.0	1.54488
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978364
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.28356
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7J9-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Selisistat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0204872
r3 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03145
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
arteriosclerotic cardiovascular disease	GWASdb SNP-Disease Associations	1.0	0.438821
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spleen_3c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.15669
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Tazemetostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157845
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXC2_01_236	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.73175
BRD-K83972459_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MHHCALL4	CCLE Cell Line Gene CNV Profiles	1.0	2.12763
mantle zone of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2477
BRD-K39037393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29301
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A58767537_afatinib_BT20_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235516_0_v_1_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWOO-0826-SM-48TCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.832
mRNA_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE77108_3_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A101D	GDSC Cell Line Gene Expression Profiles	1.0	1.51706
TAL1	MotifMap Predicted Transcription Factor Targets	1.0	null
A549_BMS-536924_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.01401
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49585
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH82	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42906
BRD-K69491845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57709
BRD-K27356753	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21234
Alzheimer Disease	DisGeNET Gene-Disease Associations	1.0	null
GTEX-R55G-0126-SM-48FDS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937758
BRD-K41809155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35249
BRD-K56336567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.03702
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.139
RAD21_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26582
BRD-A06471483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.99319
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12381304-41467_2025_63299_MOESM6_ESM.xlsx-Diff-GeneExp-Supplementary_Data_4d_Differentially_expressed_genes_between_WD_vs_Het-KD_padj_0_01_Log2_Foldchange_2_total_of_135_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-1207-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
GSE203308_4_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Wt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	96.7685
PMC8704271__F1	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14728
paracentral lobule, posterior part, left, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07991
r7 part of the nucleus of Roller	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08229
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.849097
BRD-K05411364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15294
BRD-K13299646	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2721
SOX9_01_309	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59142
BRD-K67399222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00991
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26306
A549_PCI-34051_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161108
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
A549_Sirtinol_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163109
BRD-K28820796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08974
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1037
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135030_8_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10169359-13058_2023_1653_MOESM1_ESM.xlsx-Table_S9-Table_S9_Genes_differentially_expressed_between_TP53_mutant_and_wild-type_pBCs_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE172016_2_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
JJN3	CCLE Cell Line Gene Expression Profiles	1.0	1.50343
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN014_HEPG2_24H:L03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1146
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE127790_6_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36451
ion binding	GO Molecular Function Annotations 2015	1.0	null
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	9.4519
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04058
GSE242083,GSE242098_3_v_0_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U3ZN-0002-SM-3NMDF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4924
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5700-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85294251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71071
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.34229
occipito-temporal gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08368
ACSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54225
GTEX-S4P3-1326-SM-4AD6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83991
MZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.953926
RCOR3	ChEA Transcription Factor Targets	1.0	null
BRD-A84816049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74678
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98061
HCC33	CCLE Cell Line Gene Mutation Profiles	1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984285
NCI-H596	COSMIC Cell Line Gene Mutation Profiles	1.0	null
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885246
GTEX-TSE9-0126-SM-3DB83	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4908
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09967
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GSE86507,GSE86509_3_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.861121
Lung squamous cell carcinoma_LUSC_TCGA-56-8305-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.940118
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11435
GSE223893_4_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TSE9-2826-SM-4DXTF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96662
CRCGN013_HEPG2_24H:H21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.07213
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.42275
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.928865
claustrum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.6379
AR-35650195-DSRCT-HUMAN-MESENCHYMAL-SARCOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE233647_4_v_6_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF816	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.4226
GTEX-OOBJ-0326-SM-33HBO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10657
primary visual cortex (striate cortex, area V1/17)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04423
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE150557_1_v_0_dnmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.52658
18778486-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60031
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00705
EPHA4_knockout_226_GSE34430	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.72413
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8A-MLX_3T3_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RWS6-1926-SM-47JXY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15717
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.13041
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47274
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAKI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04622
Mitotic arrest phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
GSE244072_10_v_3_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.07914
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93463
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	6.7383
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181513_2_v_1_usp7_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K63757821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03894
hypersensitivity reaction disease	GWASdb SNP-Disease Associations	1.0	0.221063
GTEX-WVLH-0226-SM-3MJG6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16852
BRD-A34774643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18159
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25345
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5105
red nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09372
GSE193588_3_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050138
GSE195559_3_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
kidney_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.21878
GSE182680,GSE182683_5_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.124
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-C_FUS-DDIT3-eGFP_vs_eGFP-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
RNF208	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01431
NANOG-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ATP5MG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41681
BRD-K67229323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03542
GSE48812_3_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.862977
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08795
GTEX-X5EB-2426-SM-4E3HX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1061
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R53T-1226-SM-48FCT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871767
SNU869	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05635
COUP direct repeat 1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE202434,GSE202438_6_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HSP90AB1	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-RWSA-0626-SM-2XCBD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20369
CTCF-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56153
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08216
PCI-15A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CRCGN011_HEPG2_24H:L12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.92485
MYC	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C6-06A-12R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
STIM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00589877
A549_Abexinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.00989907
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE182680,GSE182683_0_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.85339
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4091
abnormality of myeloid leukocytes	GWASdb SNP-Phenotype Associations	1.0	0.182944
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46951445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.78069
GTEX-WY7C-1126-SM-3NB3A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0764
BRD-K93519076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0601
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0807
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.975889
GSE240344_1_v_0_uxs1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147056_2_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WFG8-0426-SM-3GILD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957573
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
a549	HPA Cell Line Gene Expression Profiles	1.0	1.10991
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.85583
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44777
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU7-0001-SM-3NMAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11432
A549_Divalproex Sodium_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149586
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214931_1_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9169777-pnas.2120787119.sd07.xlsx-Sheet1-Dataset_S7_Significantly_differentially_expressed_genes_between_G2_and_GATA3_WT_T-ALL_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900301
Dorsal claustrum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.05923
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66867
BRD-K53772256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01755
Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10175786-Table4.XLSX-Sheet_1-GSE9750_AND_GSE7410_NOT_GSE63514_NOT_Ferrotosis_genes_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01831
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.0355
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15595
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.976693
BRD-K81751970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07972
BRD-K63787803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49954
primary auditory cortex (core)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.94797
Brain Lower Grade Glioma_LGG_TCGA-DU-A76L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXA1-26769127-CHIP-SEQ-PDAC-CELL-LINE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NR5A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00599996
GSE202603_3_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE261563_9_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9618568-41467_2022_34255_MOESM5_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	1.16913
16849537-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1937	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.14442
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08068
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
medial subdivision of area 10	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.374
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.20661
BRD-K05086663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05836
CA SKI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0915
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4BB-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K63364685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34359
mantle zone of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4184
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.13982
SKMEL1	CCLE Cell Line Gene CNV Profiles	1.0	1.81985
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898766
cleft	GeneRIF Biological Term Annotations	1.0	null
BRD-K15028515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85063
CRCGN013_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09709
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88485
SLC29A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72327
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70C-01A-21R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K67075780_TGX-115_A549_6.0_h_160.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07728
outer CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.70868
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47951859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00565
LSM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84353
Supramolecular polymer	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
CAMK2N1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04659
GSE226249_2_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K73357447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.60997
GSE77108_6_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Osteochondrodysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
H3K4me1_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Nucleus of the lateral olfactory tract, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61619
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE233679_5_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC2998	DepMap CRISPR Gene Dependency	1.0	3.27788
GSE203308_1_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_10_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	1.0	2.23722
transferase activity, transferring phosphorus-containing groups	GO Molecular Function Annotations 2015	1.0	null
RING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23734
BRD-K60848736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68786
Sarcoma_SARC_TCGA-IE-A6BZ-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-A61C-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A13983189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87104
GTEX-S4Q7-0003-SM-3NM8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834965
A549_Avagacestat_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0189611
A549_CEP-33779_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.013758
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3154	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Lung squamous cell carcinoma_LUSC_TCGA-22-0944-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF15_KO_GDS4780_419_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03926
hsa-miR-3181	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-U3ZG-0001-SM-47JYF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98777
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.833475
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-1.55671
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.958937
BRD-K44139682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12911
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.01382
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.495
dementia	GWASdb SNP-Disease Associations	1.0	0.62363
BRD-K57035236	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46294
COLO783	CCLE Cell Line Gene Expression Profiles	1.0	1.42465
ACAD8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00547156
BRD-A48228341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.18802
principal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82751
FOSL2	ENCODE Transcription Factor Targets	1.0	null
BRD-K62460895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0073
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53117
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
atherosclerosis	GWASdb SNP-Disease Associations	1.0	0.670682
RBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15321
DDIT4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29973
S117	DepMap CRISPR Gene Dependency	1.0	6.7698
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K91511557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21702
GSE131649_4_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K54265757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2538
YY1	ENCODE Transcription Factor Targets	1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0051
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TE441T	CCLE Cell Line Gene Expression Profiles	1.0	1.41016
EW-7	COSMIC Cell Line Gene CNV Profiles	1.0	2.15402
BRD-K41504921	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10132
PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-WT-gene_symbol_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-R45C-0926-SM-3GAD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17276
abnormality of lipid metabolism	GWASdb SNP-Phenotype Associations	1.0	0.574776
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4893-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heart conduction disease	GWASdb SNP-Disease Associations	1.0	1.10764
H3K4me1_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_Fasudil_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0223494
non-caseating epithelioid cell granulomatosis	GWASdb SNP-Phenotype Associations	1.0	0.517529
KLF15_KO_GDS4780_509_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41089
psychotic disorder	GWASdb SNP-Disease Associations	1.0	0.300032
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_02_199	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.65966
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STON2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00500097
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15939
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LB2241-RCC	GDSC Cell Line Gene Expression Profiles	1.0	1.64433
CTCF	MotifMap Predicted Transcription Factor Targets	1.0	null
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_7_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
SP in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06977
A549_AICAR_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0181757
EOMES_OE_GDS5077_65_human_RUES2	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
musculoskeletal system disease	GWASdb SNP-Disease Associations	1.0	0.077267
Mathematical Ability	DisGeNET Gene-Phenotype Associations	1.0	null
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-DX-A6Z0-01A-13R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HS729	CCLE Cell Line Gene CNV Profiles	1.0	1.44877
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD300E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00575215
rt4	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69387464	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61542
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5978-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superior occipital gyrus, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.987364
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-172 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.757
BRD-K64558129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13063
GTEX-R55G-1626-SM-48FF4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15174
BRD-K68395284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60596
ChIP_CTCF_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K56515112_6alpha-methyl-11beta-hydroxyprogesterone_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4091
A549_GSK J1_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161592
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
hsa-miR-342-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-U3ZH-1426-SM-4DXSR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89463
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3373-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102505_6_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86654
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878814
SOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25178
Brain disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
A549_SGI-1776 free base_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.022419
Sarcoma_SARC_TCGA-DX-A1KW-01A-22R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28720546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38473
Nucleus of the trapezoid body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.31048
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4XY-0326-SM-46MVZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19154
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97665
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.4051
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33414
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13087
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3306-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66216147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75286
Mediodorsal nucleus of the thalamus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06584
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19H-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K11636255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38091
GSE137914_0_v_3_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10140619-mmc5.xlsx-Rank_Beta1-Beta3-Gene_BHLHE22	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NFK9-0326-SM-3MJGV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957318
coronary artery disease	GWASdb SNP-Disease Associations	1.0	1.62029
FLT4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00592116
hsa-miR-548d-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CHRM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00509039
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46506
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21433
Lymphoid-primed multipotent progenitor cell(LMPP)_Umbilical cord blood_Human	CellMarker Gene-Cell Type Associations	1.0	null
vascular dementia	GWASdb SNP-Disease Associations	1.0	0.949336
OCUBM	DepMap CRISPR Gene Dependency	1.0	2.50494
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.990459
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Hemochromatosis type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.289
BRD-K54657536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1053
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-A4M6-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BACH1-22875853-CHIP-PCR-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.66769
GSE133661_0_v_1_c19orf12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_4643_KO_Wwc2_SRP151543	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.40438
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
respiratory system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045925
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hydrocortisone_homo sapiens_keloid scar_gds3071	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC3117129-mp2010119x5.xls-CRS_Amg-Unnamed_5_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05962
disease	GWASdb SNP-Disease Associations	1.0	0.154498
A549_JQ1_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015438
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05926
496100319_HIP_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.1245
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
MTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05959
protein serine/threonine kinase activity	GO Molecular Function Annotations 2023	1.0	null
mRNA_SALL4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE165307_3_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15537
RAD21_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal peripheral nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.40409
BRD-K03902845	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21437
BRD-K16357911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.47171
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0332
BRD-K66541877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93786
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A19500257_geldanamycin_A375_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE217105_0_v_1_gemcitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-0002-SM-3NMDC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.940266
superficial stratum of r3Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29462
BRD-K72468471	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13687
AM-38	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.05
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.152132
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
20368555-TS-1	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
KYSE-150	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.995975
TBX3-20139965-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_17309_KO_Ddx25_SRP247988	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.2916
A549_Lenalidomide_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.026937
oocyte	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
BRD-K23957028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.83554
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-WYJK-1026-SM-3NM8W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42403
PMC12629863-CAC2-45-1547-s002.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Kinases_predicted_to_phosphorylat_YY1_at_Ser247_YY1	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10676
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.34374
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central gray substance of midbrain, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.993959
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.872479
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.856169
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K63436213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11917
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-0126-SM-4IHLP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.863546
Brain_CT2_Splat 421	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.920043
ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-WYJK-1726-SM-3NM9U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03991
COLO678	DepMap CRISPR Gene Dependency	1.0	4.27097
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06538
Prostate adenocarcinoma_PRAD_TCGA-G9-7523-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cognitive disorder	GWASdb SNP-Disease Associations	1.0	0.615118
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE48812_0_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-N417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18594
GSE146982_4_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
YKT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42775
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49112
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XV7Q-1826-SM-4BRUV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36806
Perturb_6250_KO_Ago2_SRP041835	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Alzheimer's disease (cognitive decline)	GWAS Catalog SNP-Phenotype Associations	1.0	0.266721
GSE131649_2_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PF-00562151-00-5922	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K94088431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34509
c4orf6	GeneRIF Biological Term Annotations	1.0	null
BRD-K00586442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20719
phosphotransferase activity, alcohol group as acceptor	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-1913	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28314528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2441
NCI-H2023	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51781
EJM	DepMap CRISPR Gene Dependency	1.0	6.91013
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AXIN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00477013
BRD-K66985689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71472
GSE169205_3_v_2_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JJ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K56401968	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96696
GSE169152_3_v_1_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE86507,GSE86509_3_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_2-Methoxyestradiol_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0222962
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07049
BRD-A31962514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08374
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08611
BRD-K12918607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43255
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95653
H3K4me1_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INSM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8333
CRCGN014_HEPG2_24H:K13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.7602
A549_Zileuton_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152525
MERO14	DepMap CRISPR Gene Dependency	1.0	3.82291
A549_Selisistat_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166996
shsy5y	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
intermediate stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54618
BRD-K51577639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.63073
claustrum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.36653
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.59941
SCLC-22H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35685
lung cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.055862
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.917667
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_6_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_8_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33865
BRD-K32944375_NCGC00184834-01_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DAOY cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.339
NCIH2196	CCLE Cell Line Gene Expression Profiles	-1.0	-1.5174
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40033
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.23997
Protein kinase, ATP binding site	InterPro Predicted Protein Domain Annotations	1.0	null
Cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
electrocardiography	GAD Gene-Disease Associations	1.0	null
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.823577
NCI-H1781	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04708
Duodenum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADORA2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00644624
Superior colliculus, motor related, intermediate gray layer, sublayer b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01564
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.127
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.84756
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	1.62515
GTEX-RTLS-2626-SM-46MUJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05783
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r6 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47463
SOX13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3456
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.49195
BRD-K70870890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.71743
GSE233679_6_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K06816455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45041
Perturb_5374_KO_Setdb1_SRP226379	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.9419
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
OLFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49063
BRD-K49584663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02173
CREB1	ENCODE Transcription Factor Targets	1.0	null
GNL3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60619
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-A4D0-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2950-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K35520972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08445
GSE183327,GSE183328_1_v_0_ddit3_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K87547250_KUC104218 KUC104218N_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
A549_Daphnetin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135086
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.880383
A549_MC1568_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0137048
A549_Epothilone A_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0182374
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3322-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16025
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.853312
BRD-K45200389	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34715
protein phosphorylation	GO Biological Process Annotations 2015	1.0	null
BRD-K76588894	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60545
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50335
BRD-K67626198	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06845
mRNA_MYC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Lipoproteins, LDL	dbGAP Gene-Trait Associations	1.0	0.059114
GSE233679_14_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4164-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K41719231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.22608
GSE226249_0_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.118
abnormality of brain morphology	GWASdb SNP-Phenotype Associations	1.0	0.14197
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
BRD-K77987907	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34052
BRD-A79768653_sirolimus_MDST8_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
chp126	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.977
mania	GWASdb SNP-Phenotype Associations	1.0	0.685437
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.40905
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peripheral neuropathy	GWASdb SNP-Phenotype Associations	1.0	0.40409
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A84O-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
GTEX-WYBS-0926-SM-3NM94	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3655
BRD-K67566344_KU-0063794_EFO27_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K01371603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05357
NUGC4	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.33789
BRD-K94962942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14258
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55940699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25826
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31272
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050753
BRD-K63547380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57985
NR3C1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69248736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.57025
SIRT6	ENCODE Transcription Factor Targets	1.0	null
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.93323
Serum Albumin Measurement	DisGeNET Gene-Phenotype Associations	1.0	null
BRD-K73587666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53398
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.811524
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13361
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.33583
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GRHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3786
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.18724
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30053
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IALM	CCLE Cell Line Gene CNV Profiles	1.0	2.42354
septal nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.867745
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_PCI-34051_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156693
HDAC1	ENCODE Transcription Factor Targets	1.0	null
17510434-Table2	GeneSigDB Published Gene Signatures	1.0	null
insulin resistance	GWASdb SNP-Phenotype Associations	1.0	0.431824
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-OOBJ-0826-SM-3NB2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43484
S1PR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0064956
BRD-K21253219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6855
bone remodeling disease	GWASdb SNP-Disease Associations	1.0	0.387883
CTCF_SK-N-SH_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.7483
mantle zone of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29043
BRD-K95435237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29522
11823860-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NR3C1	ENCODE Transcription Factor Targets	1.0	null
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37647
BRD-K13859368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17862
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
r4 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28503
Perturb_15584_OE_MIR483_SRP252353	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-15.6084
GSE48812_2_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE232564,GSE232566_0_v_2_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.22709
A549_G007-LK_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155729
mood disorder	GWASdb SNP-Disease Associations	1.0	0.33652
GSE213588_9_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08102
HTR1E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00718001
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
REST	ChEA Transcription Factor Targets	1.0	null
Spondyloepimetaphyseal dysplasia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.018
GSE207471_2_v_3_btla_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE182680,GSE182683_5_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE201110_0_v_1_sirt4_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of central motor function	GWASdb SNP-Phenotype Associations	1.0	0.487671
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917401
FOXH1-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE226249_0_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
midbrain raphe nuclei	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18102
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.80764
Lung adenocarcinoma_LUAD_TCGA-44-5645-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJYA-1026-SM-4KL21	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905218
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151782_1_v_0_aim2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CALB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00611817
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15537
CDK2_knockdown_90_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.67846
NEU	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.759
PMC3419980-leu201249x4.xls-H3K9Ac-RUNX1ETO_peaks_2fold-All_gene_regions_overlapping_with_RUNX1-ETO_peaks_changing_histone_acetylation_more_than_2-fold_after_knock-down_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HK2	CCLE Cell Line Gene Expression Profiles	1.0	1.84237
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
commissural pretectal domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20313
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_XAV-939_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155631
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049092
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936917
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49671
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28895
BRD-A19962819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05776
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93463
BRD-K42713448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24415
PMC8185471-mmc4.xlsx-D4-DEGs_between_SOX15_KO_DPs_and_WT_DPs_cells_at_day_4_padj_0_05_Log2FoldChange_0_5_SOX15_KO_WT_or_Log2FoldChange_-0_5_SOX15_KO_WT_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.04803
abnormality of cellular immune system	GWASdb SNP-Phenotype Associations	1.0	0.092178
BRD-K99036206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64759
GTEX-VUSG-2426-SM-4KKZG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999791
BRD-K67602895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.99945
PMC12518476-10067_2025_7574_MOESM8_ESM.xlsx-Sheet1-Up_regulated_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-7937-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K68084083	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03649
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRRK2_mutant_33_GDS4401	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.00209
PFDN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55281
H3K27ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_Triamcinolone Acetonide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143525
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15462
BRD-K66734120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22265
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04086
A549_PD98059_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165778
GEO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	2.38201
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
NCI-H2452	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00085
GSE149035_1_v_0_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K21201014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.11621
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A19037878_trichostatin A_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K37657772	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09776
GSE233679_12_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_15189_KD_TP63_SRP056637	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0852
subcuneiform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38322
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZM-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10529
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-A02481876_Importazole_A375_24.0_h_60.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11089039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05886
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03978
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.217353
Prostate adenocarcinoma_PRAD_TCGA-HC-A8D0-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_8_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7192
BRD-K52406139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19507
18425577-TableS3a	GeneSigDB Published Gene Signatures	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28952606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53829
BRD-K83481256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3809
GSE148262,GSE150691_1_v_0_hdlbp_human	RummaGEO Gene Perturbation Signatures	1.0	null
AURKAIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35195
primary visual cortex (striate cortex, area V1/17)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.852374
A549_PCI-34051_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0183072
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF-21964334-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K30121969	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15261
intermediate stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03215
GSE186483_6_v_4_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZSCAN31	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.112
MAP1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00721172
A549_Ofloxacin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144371
kidney disease	GWASdb SNP-Disease Associations	1.0	0.839855
GSE214931_4_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K03479638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9786
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKGIIIA	DepMap CRISPR Gene Dependency	1.0	2.50974
PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1FLI-KDM6A_genes-Genes_associated_to_EWSR1_FLI1-KDM6A_peaks_in_A-673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
T3M10	CCLE Cell Line Gene Mutation Profiles	1.0	null
CAR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A15297126_FLUOCINONIDE_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13656
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsal part of CoP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41707
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.958988
ITGA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00679012
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K31462164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73153
NH-12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE130401_6_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Fedratinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155287
Celiac Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7435-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-2110	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.31351
hypertension	GWASdb SNP-Disease Associations	1.0	1.02249
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38917
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MDAMB435S	CCLE Cell Line Gene Expression Profiles	1.0	1.56224
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888456
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.83313
PMC11390959-41598_2024_70075_MOESM3_ESM.xlsx-520_DMD_common_down_gene_list-HES4_HES4	Rummagene Transcription Factor Associations 2026	1.0	null
MLMA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
magnocellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23026
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.82731
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_4303_KO_Serpine1_SRP179032	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.39784
BRD-K63665694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1518
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Movement disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826297
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
heart_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.59923
A549_TG101209_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158984
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:E20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.06129
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A375	GDSC Cell Line Gene Expression Profiles	1.0	2.26256
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3671	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
GSE229671,GSE229673_2_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R3RS-0126-SM-3GIJL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93397
GSE210655_3_v_7_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
spleen_3a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.868091
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.5238
GTEX-Q2AH-0526-SM-2I3ED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50187
BRD-K58614056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07953
Temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.832
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A42K-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7545
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969275
GSE174498,GSE174500_0_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A62995832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19873
Lung squamous cell carcinoma_LUSC_TCGA-85-A4CN-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22825
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050656
CTCF_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-0626-SM-46MVQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12338
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69656
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9618568-41467_2022_34255_MOESM4_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G3_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A48237631_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K86903429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62365
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.861955
pedigree	GeneRIF Biological Term Annotations	1.0	null
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.85166
Precommissural nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40311
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M6-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB17	DepMap CRISPR Gene Dependency	1.0	4.08976
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.82853
BRD-A82238138_Budesonide_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
kasugamycin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20368
specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.248554
BRD-A63501481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.86147
IRAK4_knockout_41_GSE12124	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.00464
GTEX-XMD1-0011-R1A-SM-4AT4C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04442
BRD-K55508908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66908
GTEX-XUJ4-0626-SM-4BOOO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10381
RAB11FIP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00492808
A549_Alisertib_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124888
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54916
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04337
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEL4-2126-SM-447AE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06395
Perturb_305_KD_Pabpn1_SRP318863	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-T5JW-0926-SM-4DM5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857593
celiac disease	GWASdb SNP-Disease Associations	1.0	0.986376
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.368
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57149
kidney_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.62223
Hip	dbGAP Gene-Trait Associations	1.0	0.617164
BRD-U64521890_XMD16-144_SKBR3_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
macromolecule modification	GO Biological Process Annotations 2015	1.0	null
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K44935022	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89288
BRD-K03406345_azacitidine_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2615
JUND	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_17230_KD_CCM2_SRP389914	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.20056
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CDK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58298
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K94012289_OSI-027_PC3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12567
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09564
BRD-K72717797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50716
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Superior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.267
A549_SGI-1776 free base_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145722
ABL1_knockdown_100_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.61974
GSE121866_1_v_3_six4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ECGI10	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80331
CLDN1_OE_GDS3510_31_human_CL1-5 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2690-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K13534347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17121
CHD7	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SOX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6201
Movement disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.928
artery disease	GWASdb SNP-Disease Associations	1.0	0.382114
PDCD10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00501925
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10335
cerebral ischemia	GWASdb SNP-Phenotype Associations	1.0	0.383167
Central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
Weyers acrofacial dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
Uterine Carcinosarcoma_UCS_TCGA-QN-A5NN-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-w_SRPK2-KD-mouse_kinase_AR	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36451
OVISE	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73545
GTEX-SN8G-0001-SM-3NM8L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60536
A549_CUDC-907_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0133688
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5099-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K22606370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24403
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
RTEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0795
abnormality of the eye	GWASdb SNP-Phenotype Associations	1.0	0.083368
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.08206
GSE193258,GSE193259_5_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
15831697-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-01A-31R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DRAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00458908
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.6415
HCT-116	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A549_Obatoclax Mesylate_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124035
A204	GDSC Cell Line Gene Expression Profiles	1.0	1.88427
GSE95077_1_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_PFI-1_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0124905
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_SRT2104_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0189104
Inflammation	CTD Gene-Disease Associations	1.0	1.1529
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73068
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Pelitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0210259
Kidney Chromophobe_KICH_TCGA-KN-8436-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
salivary gland	HPA Tissue Gene Expression Profiles	-1.0	-0.986096
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.575
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K02362691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32519
GTEX-XLM4-2026-SM-4AT4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.885995
hsa-miR-4527	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0226-SM-3DB84	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977194
medial part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40252
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3879
H2BK5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AKR1C1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00501532
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.846527
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95807
small molecule binding	GO Molecular Function Annotations 2015	1.0	null
GSE206516,GSE206518_5_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GCH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0049735
SNU349	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64746
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144347_1_v_0_crnkl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32012
CAL-72	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K68676343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56871
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE70935_1_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of macrophages	GWASdb SNP-Phenotype Associations	1.0	0.277916
A549_Cediranib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158927
ChIP_H3K27me3_20682450_humanESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Perturb_4220_KO_Hoxa2_SRP092451	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.38788
A549_AG-14361_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0137397
hsa-miR-761	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE202434,GSE202438_9_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RUNX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4295
A549_Fulvestrant_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014791
GTEX-R45C-1226-SM-48FEE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928046
BRD-K15620114	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82295
r3 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00315
BRD-K23669327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02779
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.901454
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.995975
Lung adenocarcinoma_LUAD_TCGA-75-5146-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12135
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94954
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VJ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PMC11263707-41419_2024_6896_MOESM4_ESM.pdf-14-TCF7L2_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
A549_G007-LK_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142907
BRD-K25737009_-666_HEC108_6.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8I7-01A-21R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95901403_S1118_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PL45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.93463
GSE214823,GSE214824_0_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMEM88B_KD_GPL10558_471_human_cardiovascular progenitors cells differentiated from hES cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-SIU7-0426-SM-2XCDX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
TMD8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52445
GSE218727_2_v_3_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_4_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SERPINA6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00440034
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE152441,GSE152442_1_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Superior olivary complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.34014
GTEX-WOFM-1326-SM-3MJFR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10821
mantle zone of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05215
PMC8481886-Table_2.xlsx-A_subsets-AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_357_KD_SIRT5_SRP311327	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
A549_Tucidinostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0174461
STAT3	ChEA Transcription Factor Targets	1.0	null
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41568
GSE211126_1_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nucleus subceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.956531
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QV44-0526-SM-2S1RE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21814
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.62908
EBC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32139
GTEX-QLQ7-0526-SM-2I5G3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10813
r5 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60305
BRD-K19231873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66641
A549_Hesperadin_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0112839
GSE146982_0_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_AMG-900_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0201512
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909951
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_ITSA-1_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0132477
Rectum adenocarcinoma_READ_TCGA-AF-2691-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LF-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Trametinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169561
HFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00487
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04141
GTEX-XQ8I-0126-SM-4BOPL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20316
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59059
Rectum adenocarcinoma_READ_TCGA-AF-2689-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03589
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PCM6	CCLE Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K69834831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68641
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.01763
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K21124684	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35395
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
BRD-K32537206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0333
Perturb_16830_KO_Cldn18_SRP096968	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM2664	CCLE Cell Line Gene Expression Profiles	1.0	1.9381
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16197
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01221
GTEX-XOT4-1126-SM-4B66E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839306
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K01534436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70001
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Dacinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016158
A549_Resminostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0109063
PMC9894241-pnas.2211429119.sd05.xlsx-G4_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GSE183041_1_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Entacapone_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0215976
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16826
CRCGN009_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.59435
BRD-K95080525_NCGC00183401-01_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7871-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_13_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C10	DepMap CRISPR Gene Dependency	1.0	2.00366
BRD-K84836394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01813
Coronary artery calcified atherosclerotic plaque (130 HU threshold) in type 2 diabetes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.26654
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE175787_13_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNHIT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61802
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29452
TAF1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3609	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CRCGN008_HEPG2_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00625
SUZ12-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10901781-41467_2024_46134_MOESM12_ESM.xlsx-Supplementary_Data_9-Supplementary_Data_09_Differential_expressed_genes_in_RUNX1-mutated_AML_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.9009
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19178
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.58109
A549_Iniparib_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0227361
Perturb_4651_KO_Tip55_SRP134924	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.09788
Mouth floor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.948
BRD-K09635314_-666_A549_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.44518
GSE233647_4_v_5_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K63030320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12587
PMC7373278-pone.0236187.s013.xlsx-MCF7_genes_overexpressed_in_AR-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_9086_KO_YAP_SRP297717	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
decamethonium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15989
GSE195568_3_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K61139423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18704
GSE232714_0_v_1_raver1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923522
GTEX-XQ8I-2026-SM-4BOOL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832792
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.059
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840213
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885246
BRD-A01848933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66865
BRD-K57014223	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47655
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.29463
CD200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29918
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.787
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63136
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16733
BRD-A19037878_trichostatin A_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_12580_OE_STK32B_SRP261296	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	16.9352
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126345_7_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IGROV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
purine ribonucleoside binding	GO Molecular Function Annotations 2015	1.0	null
hsa-miR-548ac	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE233679_14_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9585487-NIHMS1838959-supplement-4.xlsx-Upregulated-Table_S3_FOXC1_regulated_genes_FOXC1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835898
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF354C	JASPAR Predicted Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-8500-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Squamous Cell Carcinoma Of Mouth	DisGeNET Gene-Disease Associations	1.0	null
CGP74514A	LINCS KinomeScan Kinase Inhibitor Targets	1.0	1.04035
A549_PD98059_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138499
GTEX-S3XE-0626-SM-4AD6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890203
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43341
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE195663_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.2096
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
H3K4me1_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18493
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.851062
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3069
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885246
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932271
GTEX-X5EB-0726-SM-46MVR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05873
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.973233
CTBP2	ENCODE Transcription Factor Targets	1.0	null
Brain_CT2_Splat 428	HuBMAP ASCT+B Annotations	1.0	null
GSE202434,GSE202438_13_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE119978,GSE180930_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Divalproex Sodium_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0240132
Brain Lower Grade Glioma_LGG_TCGA-CS-5396-01A-02R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.199267
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.4513
BRD-K86109840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36704
BRD-K36204977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05554
BRD-A94698726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3146
GSE233679_6_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Pracinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.011539
Mild Mental Retardation	DisGeNET Gene-Disease Associations	1.0	null
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-486-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
RCM1	CCLE Cell Line Gene CNV Profiles	1.0	1.89573
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
olivary pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41517
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.999641
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24779
BRD-K92433833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54002
snoutepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.07042
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131649_4_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07862
mRNA_EOMES_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebrovascular disease	GWASdb SNP-Disease Associations	1.0	0.737324
GTEX-QXCU-0926-SM-48FEP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890351
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.869731
GTEX-S32W-2026-SM-4AD6E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988221
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_CYC116_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140083
PMC5798892-41421_2017_3_MOESM7_ESM.xlsx-Veh_KO_vs_WT-Supplementary_Table_S2-1_Up-_and_downregulated_genes_in_ATF6_cells_relative_to_ATF6_cells_in_the_presence_of_Vehicle_early_passage_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-679	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hek293	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
Sarcoma_SARC_TCGA-UE-A6QU-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24667
PMC9894241-pnas.2211429119.sd05.xlsx-G7_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GSE261563_9_v_4_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r2 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29201
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7245-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6238_KO_Setd1a_SRP365947	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.52526
LAMA84	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40002
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828307
GSE223893_2_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7857-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4K91ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K86884344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87874
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stomach_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.885525
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-B_FUS-DDIT3-eGFP_vs_WT-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE120612_7_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLHL14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00472817
GSE138001_0_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
stomach_3a	HPA Tissue Sample Gene Expression Profiles	1.0	0.973362
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92195
Prostate adenocarcinoma_PRAD_TCGA-CH-5763-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WFG8-0626-SM-3GILJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09204
r6 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0852
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8284321-supp_078827.121_Supplemental_Table_2.xlsx-Signature_EWS-FLI1_targets-Unnamed_2_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K09405682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44333
H3K4me1_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE135030_11_v_4_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
medial part of r5B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.94697
breast	GTEx Tissue Gene Expression Profiles	1.0	0.835342
GTEX-Q734-1926-SM-2I5EV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21069
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888875
GTEX-OXRO-0226-SM-3LK6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03745
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.04885
SIN3B	ChEA Transcription Factor Targets	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
KDM8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00391676
15897907-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14156
SS18L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12476
GTEX-S33H-1126-SM-2XCB6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25156
BRD-K17429946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02128
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE198794_0_v_1_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.503
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48119
A549_Filgotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0194085
H3K14ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8481886-Table_1.xlsx-A_subsets-iMSC_fetal_MSC_UC_MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
FOXP1	ChEA Transcription Factor Targets	1.0	null
HCC1599	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MOLT-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K75413392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.72344
Essential tremor	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.930103
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K60531990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93736
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.63765
consanguineous	GeneRIF Biological Term Annotations	1.0	null
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41685
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.11466
A549_CEP-33779_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140147
BRD-K57184137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.42814
GSE213588_9_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01018
GSE157594_3_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.285454
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4267	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
GTEX-WH7G-1526-SM-4LVMX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917079
GSE171177,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34351
Perturb_11877_OE_miR30a3p_SRP238971	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-13.8685
GTEX-T8EM-1326-SM-3DB7G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958259
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12649_KD_DIRC3_SRP191422	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Perturb_14242_KO_Tet2_SRP237910	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-12.5727
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
L-540	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Tazemetostat_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164946
A549_MK-0752_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0191532
GSE96649_1_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q2AH-0726-SM-2I3EA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851268
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52561
BRD-K23984367_sorafenib_HME1_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MON1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29545
PAX3	ChEA Transcription Factor Targets	1.0	null
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11848
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907428
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34497
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1	ChEA Transcription Factor Targets	1.0	null
BRD-K73286847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64783
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLDN1_OE_GDS3510_393_human_CL1-5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PWWP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10424
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-QDT8-0626-SM-48TYW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909185
REC1	CCLE Cell Line Gene CNV Profiles	1.0	2.48291
GTEX-WQUQ-1426-SM-3MJFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845602
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.77018
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Z-01A-21R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A89681034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3968
abnormality of the abdomen	GWASdb SNP-Phenotype Associations	1.0	0.868241
GTEX-SUCS-0226-SM-32PLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833596
hsa-miR-4446-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.119151
BRD-K77250455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51177
GSE203060_0_v_1_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K12994359_Valdecoxib_A549_6.0_h_177.6_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RAD21_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36251
phosphorylation	GO Biological Process Annotations 2015	1.0	null
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24492
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
BRD-K27881453	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05943
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4766-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86192746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21771
A549_ITSA-1_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156171
chr4_5024914_A_C_b38	GTEx eQTL 2025	1.0	2.40545
BRD-A31916785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74101
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FLI1	ChEA Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.924697
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46807
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX3-FKHR-20663909-RHABDOMYOSARCOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K11581306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36861
intermediate stratum of 5BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60044
CHD1	ENCODE Transcription Factor Targets	1.0	null
CRCGN011_HEPG2_24H:H22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2101
GTEX-RUSQ-0526-SM-2TF72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08977
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.5948
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of immune system physiology	GWASdb SNP-Phenotype Associations	1.0	0.098502
BRD-A17902629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73775
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.829498
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.183
GTEX-UJMC-1226-SM-4IHLI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02417
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Tongue-endothelial cell of lymphatic vessel	Tabula Sapiens Gene-Cell Associations	1.0	-0.130541
NOX3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00681473
GSE127790_9_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-O5YW-1826-SM-2YUN2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982679
GTEX-T6MN-0726-SM-32PML	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858674
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41862
hsa-miR-573	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Penis_Foreskin_Melanocyte_Primary_Cells_skin03	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.829053
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1343	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054263
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.931554
HEC1A	CCLE Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Disulfiram_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0260329
9+2 non-motile cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.044
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST12-Unnamed_8_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1599	CCLE Cell Line Gene CNV Profiles	-1.0	-2.37577
evidence	GeneRIF Biological Term Annotations	1.0	null
A549_ITSA-1_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163849
GTEX-T6MN-1226-SM-3NMA5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30343
Bell's palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.979326
WM793	CCLE Cell Line Gene Expression Profiles	1.0	1.59214
A549_Patupilone_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0198742
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-P4PQ-0326-SM-2HMJ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04199
BRD-K17372597	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50744
superficial stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00315
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18042
mantle zone of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40329
CTCF_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1395	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78349
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
bipolar affective disorder	GWASdb SNP-Phenotype Associations	1.0	0.685437
TCF4	ChEA Transcription Factor Targets	1.0	null
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15205
16622258-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.4719
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SNU-407	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114685_1_v_0_grin2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K62182950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.258
BRD-K05374764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18525
PPAR, HNF-4, COUP, RAR	MotifMap Predicted Transcription Factor Targets	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Givinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0107461
HS6ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28518
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K49635910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32502
GSE95077_1_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885246
BRD-K74211805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4459
hsa-miR-3616-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE206516,GSE206518_6_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
orofacial cleft	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.638282
medial part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.21253
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.06186
liver	GTEx Tissue Gene Expression Profiles	-1.0	-2.07215
chr4_5438081_T_A_b38	GTEx eQTL 2025	1.0	3.4513
hsa-miR-4763-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
PMC11979751-table_s1_trajectoryderivation_elad055.xlsx-Cluster_DE_Genes_Summary-Cluster_2_AP2_Up_GTF3A	Rummagene Transcription Factor Associations 2026	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K05185748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.98686
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86654
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900832
progressive supranuclear palsy	GWASdb SNP-Disease Associations	1.0	0.651654
NCIH322	CCLE Cell Line Gene CNV Profiles	1.0	1.6331
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
PMC10087102-LSA-2023-02054_TableS5.xlsx-Sheet_1_-_Supplementary_Table_6-Supplementary_Table_6_PITA_filtered_output_ZFP1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K09304381	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42654
CRCGN017_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0414
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07682
GSE112760,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.885246
BRD-K06408981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10135
subpretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06405
BRD-K62692910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09786
A549_Linifanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160572
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18994
r6 part of spinal trigeminal nucleus, pars oralis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48972
TE-12	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.11641
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K91361836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46216
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MIDOSTAURIN	DGIdb Drug Targets 2026	1.0	1.55682
GSE167546_1_v_2_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24681
GTEX-XXEK-0004-SM-4BRWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.851634
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE216147_0_v_3_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Adenosine triphosphate	HMDB Metabolites of Enzymes	1.0	null
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.32457
CRCGN008_HEPG2_24H:D09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.105
Prostate adenocarcinoma_PRAD_TCGA-HC-A76W-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UPJH-0001-SM-3NMDE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.13155
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHL1	CCLE Cell Line Gene Expression Profiles	1.0	1.73036
salivarygland_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.927295
AR	ChEA Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cleft Lip	HuGE Navigator Gene-Phenotype Associations	1.0	null
MCM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05066
EZH2	ENCODE Transcription Factor Targets	1.0	null
BRD-K57639176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29585
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
A549_TMP195_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0169106
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Mercaptopurine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0167497
COGN278	DepMap CRISPR Gene Dependency	1.0	2.21072
HS274T	CCLE Cell Line Gene Expression Profiles	1.0	1.90036
hsa-miR-1	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17232
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
A549_EED226_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0181444
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.825555
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050584
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548t	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
TBX3	ChEA Transcription Factor Targets	1.0	null
A549_CYC116_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0423855
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2073
SKRC31	CCLE Cell Line Gene Expression Profiles	1.0	1.43
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Acrofacial dysostosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.213
SNU245	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48258
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.97644
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98852
CRCGN015_MCF10A.TP53.M_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03395
RKO	GDSC Cell Line Gene Expression Profiles	-1.0	-1.41873
A549_S-Ruxolitinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171603
hsa-miR-488	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Supramolecular fiber	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.03203
CEBPB	ENCODE Transcription Factor Targets	1.0	null
CRCGN011_HEPG2_24H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1811
r5 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42058
abnormality of the cerebral vasculature	GWASdb SNP-Phenotype Associations	1.0	0.265032
fertilizedegg	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
ZNF263	ENCODE Transcription Factor Targets	1.0	null
TT	GDSC Cell Line Gene Expression Profiles	1.0	1.70728
GTEX-UJMC-0226-SM-4IHLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948201
accessory entopeduncular nucleus (post-migratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10679
BRD-K67075780_TGX-115_A673_6.0_h_160.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75688032	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11667
SNX17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0053295
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1487
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sensory disturbances after bilateral sagittal split ramus osteotomy	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Parafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13793
BRD-K86797399_pracinostat_HA1E_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123943_4_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K15563106_-666_AGS_6.0_h_177.6_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZSCAN16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.8861
abnormality of nervous system morphology	GWASdb SNP-Phenotype Associations	1.0	0.207882
GSE216147_2_v_3_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
647-V	GDSC Cell Line Gene Expression Profiles	-1.0	-2.03644
Lung adenocarcinoma_LUAD_TCGA-67-3772-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100340_TCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01325
MFM223	DepMap CRISPR Gene Dependency	1.0	3.0797
RFX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
MZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.15276
A549_SB431542_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0279326
Lung squamous cell carcinoma_LUSC_TCGA-77-7338-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-7109-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.54053
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.63472
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_Obatoclax Mesylate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0381859
CRX-20693478-ADULT_RETINA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K28107038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14164
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12425
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958457
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Hypertension	HuGE Navigator Gene-Phenotype Associations	1.0	null
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19568
BRD-K82135108_elesclomol_SW948_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZFP57	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.184
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12124
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.85511
GTEX-TMMY-0126-SM-4DXTP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.99654
Perturb_239_KD_CYFIP1_SRP061192	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.08282
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IKBKE_knockdown_97_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.93692
anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.77184
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7647-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139987_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRX-20693478-ADULT-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.6935
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K01478290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06903
PMC3255547-supp_007401_DMM007401TableS6.xls-EWS-FLI1_signatures-Unnamed_1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29459
line1	GeneRIF Biological Term Annotations	1.0	null
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83509
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caused	GeneRIF Biological Term Annotations	1.0	null
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K20809650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03596
GSE211357_1_v_3_atg7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-0326-SM-2HMJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04045
BRD-K68705041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42757
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMX1_Deficiency_GDS4810_324_mouse_Retinas of C57BL/6J	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
liver	HPA Tissue Gene Expression Profiles	-1.0	-1.47134
TUBB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00453612
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66909
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.835498
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29781
PPP1R11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47857
H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Cerebellum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12205
intermediate stratum of r5Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22448
Magnesium	HMDB Metabolites of Enzymes	1.0	null
RASA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54563
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular protein metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K57080016_-666_SKMEL28_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
rotenone-5920	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OTX2_silencing_GDS4472_136_human_D425 medulloblastoma (MB) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC11167905-10194_2024_1805_MOESM1_ESM.xlsx-S6-Table_S6_MR_results_of_brain_eQTLs_and_migraine_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SYK_knockdown_279_GDS3609	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.41688
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.01202
Lung squamous cell carcinoma_LUSC_TCGA-85-7844-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K13852343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17368
H3K4me1_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RAD21_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37527826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32973
GSE116894_1_v_0_tle3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A61767497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21233
MAP4K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0134
DDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01729
SW1990	DepMap CRISPR Gene Dependency	1.0	8.98051
KALS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K45813167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29229
BRD-A15079084_phorbol-12-myristate-13-acetate (PMA)_THP1_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H838	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2501
GTEX-SNOS-0003-SM-3NMAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
PMC7429792-40104_2020_487_MOESM3_ESM.xlsx-MSC_enriched_miRNA_target-NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
17069664-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
abnormal ekg	GWASdb SNP-Phenotype Associations	1.0	0.969142
connective tissue disease	GWASdb SNP-Disease Associations	1.0	0.108086
SOX14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2102
Perturb_14396_KO_SYK_SRP124678	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CHLA90	DepMap CRISPR Gene Dependency	1.0	2.92455
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.3664
GSE96649_1_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.76587
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.872045
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71A-01A-22R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K17840858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51641
superficial stratum of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49145
BRD-K12440228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87006
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC10794847-mmc6.xlsx-PIAS1_KD_down-Table_S5_Genes_differentially_expressed_with_PIAS1_knockdown_in_keratinocytes_cultured_in_the_differentiation_condition_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
HLF	CCLE Cell Line Gene CNV Profiles	1.0	1.34447
GSE211357_2_v_0_atg7_human	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06107
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08547
GTEX-P4PP-0926-SM-48TBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24435
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.38753
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE224294_4_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE134214_0_v_1_ell2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K49409947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.0533
GSE154337_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K81418486_vorinostat_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K50443235	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.88135
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6935-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMS11	DepMap CRISPR Gene Dependency	1.0	2.83064
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36181
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17462
hsa-miR-4722-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC-33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
BRD-K66993610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51018
PMC12661646-dmm-18-052290-TableS6.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
12714683-Table5	GeneSigDB Published Gene Signatures	1.0	null
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228106_0_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A13133631_FLUOROMETHOLONE_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04044
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r4 part of descending trigeminal sensory nucleus, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46807
PAX2_01_72	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.68631
GSE236486_1_v_2_arnt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE246461,GSE246463_5_v_0_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_6_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K88746179	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81851
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZN-1926-SM-4DXSG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858379
BRD-K49292348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73097
BRD-K57732605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40089
ACLY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84781
GSE186483_2_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-3691-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
r5 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22448
GSE127790_5_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K03067757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44153
A549_Mercaptopurine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146728
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Gene_Name_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27505
A549_IOX2_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0225029
BRD-K66434795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10441
hsa-miR-648	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
A549_Ofloxacin_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0116876
superficial stratum of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30981
KMRC1	DepMap CRISPR Gene Dependency	1.0	2.36664
ARL14EP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11378
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13361
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03056
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRL-0326-SM-2I3F2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08494
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46892
Anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
GTEX-XUW1-2326-SM-4BOO5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969786
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06431647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34425
mantle zone of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0852
hsa-miR-4710	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVJ-1826-SM-2S1P3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884091
PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-w_SRPK2-KD-kinase_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K74540252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83118
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00929
BRD-K47849061	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1432
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
H3K9ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K64939364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33833
GSE118617,GSE118619_0_v_3_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEPG2	CCLE Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-324-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE123943_2_v_0_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K72439355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39627
HSSCH2	DepMap CRISPR Gene Dependency	1.0	4.22133
intermediate stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12545
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor-sensory cortex (samples)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.96074
Perturb_7891_KD_EZH2_SRP321656	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Polymeric cytoskeletal fiber	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
CAKI1	BioGPS Cell Line Gene Expression Profiles	1.0	1.15335
GSE148262,GSE150691_3_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Fasudil_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0156525
BV-173	GDSC Cell Line Gene Expression Profiles	1.0	1.44159
BRD-K85357344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47911
PMC3152520-1479-5876-9-119-S2.XLS-Sheet1-STAT1_STAT1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_2_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HEL9217	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38811
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
purine ribonucleoside triphosphate binding	GO Molecular Function Annotations 2015	1.0	null
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12735
BRD-K94344573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09105
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	2.22093
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.922474
BRD-K84239940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02457
GTEX-RNOR-1426-SM-48FDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84276
GSE233679_14_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
PXYLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03804
CRCGN015_MCF10A_48H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03041
ZGLP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00675726
BRD-K04786080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21982
CBX3	ENCODE Transcription Factor Targets	1.0	null
bipolar disorder	GWASdb SNP-Disease Associations	1.0	0.788564
BRD-K16826019	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20003
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_72h_1-Unnamed_0_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K72591075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20162
EWS502	CCLE Cell Line Gene Expression Profiles	1.0	1.65597
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Spinal cord_CT1_Dorsal Inhibitory Neuron 2	HuBMAP ASCT+B Annotations	1.0	null
BRD-K89014967_S1475_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SPINK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00774401
Lung adenocarcinoma_LUAD_TCGA-64-1681-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Microtubule cytoskeleton	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
BRD-K91577886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35225
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A28105619_curcubitacin I_COV644_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain_CT2_DLIT 152	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
CLC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00607789
BRD-K96987864	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54644
MZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.56652
BRD-K00209945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0941
BRD-K14203360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64575
BRD-K44309337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44113
Prostate adenocarcinoma_PRAD_TCGA-EJ-A46H-01A-31R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K94452277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74847
Peroxisome biogenesis disorder 3A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.847
GSE216274,GSE216292_4_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73182084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3715
UMRC7	DepMap CRISPR Gene Dependency	1.0	2.97119
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38429
BRD-K68968009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80305
mantle zone of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07658
BRD-K14375485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06738
GSE149359_2_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-x_LPS-BMDCs-mouse_kinase_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69748
H3K4me1_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25551
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03385
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Mediodorsal nucleus of the thalamus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17361
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.830708
A549_SRT3025 HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133611
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.02953
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.856169
GSE233647_4_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral (parvicellular) part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07515
REST	ENCODE Transcription Factor Targets	1.0	null
GTEX-P4PQ-0426-SM-3NMCI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847675
BRD-A04618830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03519
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
r3 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0852
SOX10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.5655
SK-GT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-2626-SM-2HMK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02251
H3K4me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A42628519_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
11823860-Figure2	GeneSigDB Published Gene Signatures	1.0	null
Perturb_15339_KO_Nampt_SRP255398	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.054
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-PWOO-0526-SM-2S1Q3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13181
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182680,GSE182683_7_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HS939T	CCLE Cell Line Gene Expression Profiles	1.0	1.35856
GSE182680,GSE182683_5_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE189653,GSE203344_2_v_0_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
outer SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.864411
GTEX-O5YT-0326-SM-32PKA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963759
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.33598
H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A6YU-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GNA12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85701
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
COG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37861
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04141
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
spleen_3d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.62013
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.43176
BRD-K82107433	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06282
Alzheimer's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
GTEX-QDVJ-0426-SM-2I5FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907656
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4151-01A-01R-1188-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95145
RCOR3-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K54254994	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05659
BRD-K22668106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26894
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Protein kinase-like domain	InterPro Predicted Protein Domain Annotations	1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K01762107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29785
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in rostral cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07067
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K76937233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68487
HS821T	CCLE Cell Line Gene Expression Profiles	1.0	2.72873
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19808870-ST1	GeneSigDB Published Gene Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF-21964334-BJAB-B-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7250-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GSE149760_3_v_1_elof1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4723-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4775-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.12635
GTEX-PWCY-0526-SM-2I3ER	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88964
H3K9ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PANK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00481668
TRPV3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00499451
GSE246053_4_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77801
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
PMC6923932__F4	PFOCR Pathway Figure Associations 2024	1.0	null
BRD-K03214579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06875
Perturb_12222_KD_FOXA1_SRP267080	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.301738
H3K36me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K63829331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.87876
JARID1B-DAIN-22020125-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.350576
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73721
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32045
A549_Divalproex Sodium_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160924
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174498,GSE174500_3_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.296
BRD-K32049721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13622
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-8_DEGs_RUNX1-OE_vs_control-Gene_Symbol_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12720_KD_KMT2C_SRP110043	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
STIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77476
BRD-K90048234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05305
A549_Azacitidine_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161018
GTEX-XV7Q-2526-SM-4BRV9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33974
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_4944_KO_Rybp/Yaf2/Prc1_SRP247114	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
alcohol dependence	GWASdb SNP-Disease Associations	1.0	0.814185
IGF1_OE_GDS3484_540_human_MCF-7	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K71726959_N9-isoproplyolomoucine_PL21_6.0_h_122.55_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-1265	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Bony labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.707
r4 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12249
PPARgamma:RXRalpha	MotifMap Predicted Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5482-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.10093
Perturb_12904_KD_FOXA1_SRP313175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.1405
A549_Alendronate sodium trihydrate_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140149
Medulloblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.157
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:I10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.393
BRD-K19381111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28815
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.1499
G61	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.856169
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883143
Kidney Failure, Chronic	HuGE Navigator Gene-Phenotype Associations	1.0	null
GSE216273,GSE216292_14_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5807
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QT-1326-SM-3NMD3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949468
GSE140997_10_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-27a	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
GTEX-RU1J-1726-SM-2TF5S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903924
behavioral abnormality	GWASdb SNP-Phenotype Associations	1.0	0.19118
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3450-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WOFL-0826-SM-3MJG1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0043
Spinal nucleus of the trigeminal, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28948
BRD-K70992537	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05883
BRD-K37696710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3182
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
C6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00489714
GTEX-V955-0004-SM-3NMDH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39062
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50836978_Purvalanol A_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K26184956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62751
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.897353
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28216304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01796
PSN1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.8133
Brain Lower Grade Glioma_LGG_TCGA-DU-6397-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7248-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2	Rummagene Transcription Factor Associations 2026	1.0	null
stk32b	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4436b-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
Rectum adenocarcinoma_READ_TCGA-EI-7004-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCIMY5	CCLE Cell Line Gene CNV Profiles	1.0	1.35887
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.050124
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
protein kinase activity	GO Molecular Function Annotations 2015	1.0	null
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K57080016_selumetinib_BT20_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
18410693-TableS6	GeneSigDB Published Gene Signatures	1.0	null
vascular disease	GWASdb SNP-Disease Associations	1.0	0.313928
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4853-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-CA-04-2009(H1N1)_0Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.57736
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13479
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RQ-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K25675728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21163
BRD-K27302831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12963
BACH1-22875853-HELA-AND-SCP4-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039176
inner CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.879627
superficial stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12333
GSE95077_5_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K63970901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92417
A549_AZD1480_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152319
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52013
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26198
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64860662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2061
GSE236815_1_v_0_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4664-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07686
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F5-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE140576_0_v_2_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r2 part of ventral lateral lemniscal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28503
H4K20me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211425_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of r6Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0293
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Fasudil_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0211854
NCIH2444	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80932
CAS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74067
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-external_gene_name_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K56751279_Y-39983_PC3_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
trios	GeneRIF Biological Term Annotations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7013-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11246
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.34721
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.998665
Perturb_12544_KO_Ctnnb1_SRP194249	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.0002
BRD-K18000429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77105
GTEX-T5JW-2026-SM-4DM63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05961
SW156	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-PSDG-0326-SM-48TCP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00967
intermediate stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5364
A549_M344_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015766
populations	GeneRIF Biological Term Annotations	1.0	null
GTEX-QEG5-0926-SM-2TC64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.834861
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.13977
BRD-K89141455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.37068
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08133
BRD-K38003476_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRNKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07129
RI1	DepMap CRISPR Gene Dependency	1.0	2.25755
BRD-K45628030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63279
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31537
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42542
A549_A-366_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0217015
19808870-ST3	GeneSigDB Published Gene Signatures	1.0	null
r4 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06642
Ewing's sarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.706
GTEX-OXRK-1826-SM-2HMJE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937201
hsa-miR-548ah	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE226249_0_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RPS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47568
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74597
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bone resorption disease	GWASdb SNP-Disease Associations	1.0	0.794247
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE179974_3_v_0_carboplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PIWIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11946
squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.978917
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4728-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06322
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWOO-1226-SM-48TCO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893829
A549_Busulfan_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0273831
Cerebellar cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1869
GTEX-U3ZM-1226-SM-3DB9G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925759
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.19565
HSC-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.502
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.920019
A549_Danusertib_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0193557
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44638
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PNPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68953
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.289748
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56761
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8353-01A-21R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K68580555	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26346
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176008_0_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K78074905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66277
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93387
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31436
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20208
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14939
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19902
BRD-K95153427	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57721
GSE233679_5_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HNF4alpha_KO_GDS1915_173_mouse_Small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Penis_Foreskin_Melanocyte_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.21548
ZBTB8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61313
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76795
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
Perturb_13689_KD_TFEB_SRP033784	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-12.7265
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4812
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.834325
CRCGN017_MCF10A.TP53.M_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43202
outer CP in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35531
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
LRRK2_activemutant_159_GSE36321	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.00207
nicotine dependence	GWASdb SNP-Disease Associations	1.0	0.814185
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ATP5F1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87098
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.831583
CTCF-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SLC1A7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00551468
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88153
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-2126-SM-32PMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78282
MAX	ENCODE Transcription Factor Targets	1.0	null
Human - Motor Cortex - Subclass - Layer 6 Car3+ glutamatergic neuron, intratelencephalon-projecting	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE214823,GSE214824_6_v_2_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_3_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
wm115	HPA Cell Line Gene Expression Profiles	1.0	1.66706
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETV4_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33536
BRD-K02106348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20701
BRD-K43384508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10883
BRD-K26314798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23753
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K98301999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23218
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43851
BRD-K60946512	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27893
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.26877
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.936906
CRCGN016_MCF10A.WT.HP_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18093
GSE237040_6_v_5_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K01894374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39487
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IL17RC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00518415
GTEX-UPK5-0003-SM-3NMDI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73982
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29191
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0187
Brain Lower Grade Glioma_LGG_TCGA-TM-A84J-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_5_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BCL9L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30129
GTEX-QLQW-1226-SM-2S1Q9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993505
HIR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.74
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.995975
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240896,GSE240899_10_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69417
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.929354
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEC265	DepMap CRISPR Gene Dependency	1.0	3.6562
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q734-2226-SM-3GAD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62172
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2814-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
detected	GeneRIF Biological Term Annotations	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_ID1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
PMC12888741-13073_2026_1599_MOESM1_ESM.pdf-34-TBX21_TBX21	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.827796
GTEX-OXRP-0126-SM-3NB32	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03376
A549_PFI-1_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141402
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.80875
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Accessory facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18676
Brain Lower Grade Glioma_LGG_TCGA-VM-A8C9-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cleft palate	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.705144
ATM_knockout_74_GSE23116	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.2174
GSE137702_2_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
RC-K8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Human - Motor Cortex - Cluster - SST+ PRRT4+ Layer 1-2 GABAergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77447
GTEX-XUJ4-0526-SM-4BOON	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18969
BRD-K48827674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15698
GTEX-RTLS-1326-SM-46MUN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59899
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_1day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.66706
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903258
QPRT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00338044
GSE186483_1_v_4_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_7_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
MOB3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18409
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRX	ChEA Transcription Factor Targets	1.0	null
inferior olivary complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.894967
BRD-K17175263	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.90095
BRD-K84949119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58049
outer CP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67632
GTEx Ovary 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-6.25646
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11324
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.49773
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-0526-SM-3GAE3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901352
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
heart conduction disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.60786
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-BR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22687
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31062
Salt gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WYJK-1326-SM-3NB2T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07478
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24556
H3K4me1_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18136
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K45328741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02937
BRD-K62892366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.46008
BRD-K05471809	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53608
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K32269272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29698
BRD-K56131419	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75973
C11orf68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35713
hip	GAD Gene-Disease Associations	1.0	null
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052261
647V	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37918
layer 1 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08156
upper limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26122
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A5KC-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_SRT3025 HCl_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0120915
PMC7481169-277_2020_4194_MOESM7_ESM.xlsx-RUNX1_R139G-Unnamed_1_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70H-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12634441-41375_2025_2771_MOESM7_ESM.xlsx-RNAseq-Table_S2_Bulk_RNA-seq_GATA2_vs_control_Only_p-adj_0_05_GATA2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
deletion	GeneRIF Biological Term Annotations	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NB1643	DepMap CRISPR Gene Dependency	1.0	2.02447
U343	CCLE Cell Line Gene CNV Profiles	1.0	1.43074
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K31627533_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K95014616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46192
Neoplasm Metastasis	DisGeNET Gene-Phenotype Associations	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
all	GeneRIF Biological Term Annotations	1.0	null
schizophrenia	GWASdb SNP-Disease Associations	1.0	0.817591
BRD-A20305532	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64175
HUNS1	DepMap CRISPR Gene Dependency	1.0	5.20821
GTEx Uterus 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	-1.0	-3.8005
GTF2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44049
abnormality of bone mineral density	GWASdb SNP-Phenotype Associations	1.0	0.690584
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42965
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Triamcinolone Acetonide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0204939
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958043
anion binding	GO Molecular Function Annotations 2015	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JJN3	DepMap CRISPR Gene Dependency	1.0	2.05231
Cleft Palate	HuGE Navigator Gene-Phenotype Associations	1.0	null
Mesothelioma_MESO_TCGA-MQ-A4LC-01A-31R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JB-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSP90AA1	Pathway Commons Protein-Protein Interactions	1.0	null
RUNX1_01_159	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60498
BRD-K63209730	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49392
GSE195559_0_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4498	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.160203
GSE213588_10_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58815
Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T5-01A-12R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QEL4-1226-SM-447A4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.906544
abnormal emotion/affect behavior	GWASdb SNP-Phenotype Associations	1.0	0.305533
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4340-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K44908880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32415
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_5_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0454
BRD-K63668467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33219
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.918416
GTEX-WL46-2026-SM-3LK7U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900458
ERN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00619276
LN229	CCLE Cell Line Gene Expression Profiles	1.0	1.41027
BRD-K73114074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79482
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8791
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.734535
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7979
Brain Lower Grade Glioma_LGG_TCGA-S9-A6UA-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60948
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-885-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
homozygous	GeneRIF Biological Term Annotations	1.0	null
SR786	CCLE Cell Line Gene CNV Profiles	1.0	2.15978
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	1.48419
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2196	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K88542817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59098
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21794
ERMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09445
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.976851
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00743
SCL-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.085
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
hsa-miR-762	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
eye disease	GWASdb SNP-Disease Associations	1.0	0.143094
GSE135030_8_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOT4-0226-SM-4B66Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01197
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K23292451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00539
F11R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26299
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15338_KO_Ldha_SRP255398	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.28353
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.897935
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8419-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sensory system disease	GWASdb SNP-Disease Associations	1.0	1.00407
CCDC106	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29402
SIK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00602754
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
G121	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13656
Spinal cord_CT1_Dorsal Inhibitory Neuron 2	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-512-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
GTEX-XPT6-0001-SM-4B64G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39745
BRD-K94790210	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18117
BRD-K74855272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93579
BRD-K28159131	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3856
BRD-K50234570_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MZ7-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29981
BRD-A15454510	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00944
BRD-K68450812	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05313
BRD-K77990919	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52265
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36018
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-A_FUS-DDIT3_vs_both_controls-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A36630025_-666_MCF7_6.0_h_0.35_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.02197
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.925
A549_Pracinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0127578
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
16109776-TableS1	GeneSigDB Published Gene Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.526
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_2-Methoxyestradiol_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0194904
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44603
CTCF	ChEA Transcription Factor Targets	1.0	null
PLD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50563
dementia	GWASdb SNP-Phenotype Associations	1.0	0.836232
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
TrigeminalGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.11951
HCFC1	ENCODE Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-527	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19946
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869157
POLR2AphosphoS5_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.855416
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K30921693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48661
adenyl nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-QEG5-0326-SM-2S1PB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829092
BRD-K73768826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20995
retropontine reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19935
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5653
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24081
GTEX-SIU8-0626-SM-2XCDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00968
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Functional diarrhea	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.449
CRCGN015_MCF10A.TP53.M_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16
GTEX-QCQG-0226-SM-48U28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02259
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21507
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-2426-SM-3GILL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18086
GSE112760,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.407397
BRD-K06020071	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33929
Perturb_12659_KD_NFE2L2_SRP242008	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F9-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
cleft lip; cleft palate	GAD Gene-Disease Associations	1.0	null
CCK81	CCLE Cell Line Gene Mutation Profiles	1.0	null
PMC12171002-jcav16p2578s1.pdf-2-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
TBX3-20139965-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-TK-A8OK-01A-22R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1245_OE_MYC/BCL2/BCL6_SRP376326	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.87157
OVKATE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.63758
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40851
BRD-K51490301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29305
GTEX-RU1J-1926-SM-2TF6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56765
GSE195743_3_v_2_lhx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE213588_8_v_4_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828807
BRD-K45677957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13904
HOXB7-26014856-BT474-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mental deterioration	GWASdb SNP-Phenotype Associations	1.0	0.836232
KYSE450	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54068
adenyl ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
NB4	DepMap CRISPR Gene Dependency	1.0	2.24331
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07853
superficial stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54414
mantle zone of r6Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08593
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10140619-mmc5.xlsx-Beta3_ConVsBSL-Gene_BHLHE22	Rummagene Transcription Factor Associations 2026	1.0	null
mcf7	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Parkinson's disease motor subtype (tremor to postural instability/gait difficulty score ratio)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.61549
GTEX-XGQ4-0526-SM-4AT6C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
BRD-K50866992_tropisetron hcl_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE197555_0_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.1499
BRD-K25757432	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12995
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.623
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MR-01A-31R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
triangular septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0393
BRD-K07152092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.61249
ETCC016	DepMap CRISPR Gene Dependency	1.0	2.96743
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.112
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ORC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2443
P30-OHK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VV-A829-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Lung adenocarcinoma_LUAD_TCGA-50-6591-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-507	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
TCEAL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00457513
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-2226-SM-3TW8W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856837
MEK_OE_GDS1925_165_human_Estrogen receptor (ER) alpha positive MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29906
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.856987
18787218-tableS1	GeneSigDB Published Gene Signatures	1.0	null
r7 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07513
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216147_0_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
WIDR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21992
A549_Busulfan_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0134313
catalytic activity	GO Molecular Function Annotations 2015	1.0	null
GSE202434,GSE202438_4_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13538
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10433
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.60848
IFRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34369
SOX2	ChEA Transcription Factor Targets	1.0	null
BRD-K54814515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36555
GSE240896,GSE240899_2_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
alzheimer disease	GWASdb SNP-Phenotype Associations	1.0	1.08774
BRD-K93956318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84847
GTEX-XLM4-0004-SM-4AT5I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77498
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.064035
BRD-K21936026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04798
A172	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.10048
occipital pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.7755
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30741
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37507
GTEX-UPIC-0926-SM-4IHLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37483
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_PHA-680632_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0190321
BRD-A58767537_afatinib_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SPIRE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49041
PMC7346435-12864_2020_6860_MOESM6_ESM.xlsx-H1_ZF_Oocyte_Specific-GeneH_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K60662039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27455
A204	CCLE Cell Line Gene Expression Profiles	1.0	1.45243
EIF5AL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.60724
PPARD	ChEA Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2948
Fetalbrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.27937
hepg2	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
lingual gyrus, left, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.973438
15257931-SuppTableA	GeneSigDB Published Gene Signatures	1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07941
BRD-K35693854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37833
BRD-A07765530_(+/-)-epinephrine_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9509360-41419_2022_5262_MOESM6_ESM.xlsx-Fig_2D_MSC_targeted_RNF4-Down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Tanespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014949
mb03	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.67
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04637
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28996
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.55671
intermediate stratum of CoPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50928
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
BRD-K45498945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03774
H3K9ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RAD21_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIPK1_knockout_170_GSE39253	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-0.664409
GSE110580_1_v_0_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.92955
GTEX-QDT8-0126-SM-48TZ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02771
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5VU-01A-21R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A99990159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35755
Right_Atrium	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.31369
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QT-0226-SM-3LK68	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907901
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hyperbilirubinemia	GWASdb SNP-Phenotype Associations	1.0	0.734978
MUTZ5	CCLE Cell Line Gene CNV Profiles	1.0	2.00848
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PRRC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05419
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TPST2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00642995
A549_Lenalidomide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172473
GSE148252_1_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of r4Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28355
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02963
GSE213588_8_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18594
r2 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30863
A549_Lomustine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0214085
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4P3-1626-SM-3K2AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01139
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-TKQ2-1726-SM-4DXUP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16413
CAL120	CCLE Cell Line Gene CNV Profiles	1.0	1.6336
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OB mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05679
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-511	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.22467
H3K27me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K06251362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96037
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19457
corneal disease	GWASdb SNP-Disease Associations	1.0	1.00407
TRIM54	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00662359
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131798,GSE131804_5_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76695
SCLY	ChEA Transcription Factor Targets	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
BRD-K19009697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34774
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_BMS-536924_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142988
A549_UNC1999_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0188768
atp binding	GO Molecular Function Annotations 2015	1.0	null
Perturb_15978_KO_Tsga8_SRP254760	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.85788
GSE111660_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47959
r6 part of magnocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02789
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19103068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25068
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K65266979	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80329
TMEM88_KD_GSE43805_682_human_hES cells differentiated along the cardiac lineage	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
OCUB-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4685-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ME-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
17597811-SuppTable5	GeneSigDB Published Gene Signatures	1.0	null
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
A549_RG108_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0204357
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.28921
RAD21	ENCODE Transcription Factor Targets	1.0	null
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825493
GSE182680,GSE182683_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNAP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00846
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40206
medial part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07515
BRD-K14599588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80814
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50361
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82298
GTEX-UPK5-2326-SM-3P5Z8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28375
TEC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00434529
BRD-K08903301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34436
trochlear nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.910487
WM1799	CCLE Cell Line Gene Expression Profiles	1.0	1.75825
BRD-K33805195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16383
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.837569
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.7652
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD2/3-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r6 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84547
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7573-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Neurosphere_Cultured_Cells_Ganglionic_Eminence_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.31556
GTEX-XMD1-0826-SM-4AT52	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08437
kidney	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
Perturb_10199_KD_RUNX1/RUNX1T1_SRP291095	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.01948
GSE182680,GSE182683_10_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Microtubule	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
A549_Tanespimycin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157821
all	GWASdb SNP-Phenotype Associations	1.0	0.137633
H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
rhombomere 6	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09098
yielded	GeneRIF Biological Term Annotations	1.0	null
PDGFRA_knockdown_117_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.84277
BRD-A71962374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25739
NCI-H1048	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE233679_5_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4291	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-T6MO-1526-SM-4DM57	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900428
RIOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80168
cSARS Bat SRBD_12Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.51873
LOX-IMVI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21861
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE213588_9_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_4_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K34506374	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27856
GSE261563_7_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-5.9248
BRD-K14269958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.29649
BCL6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9336
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44197
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.28895
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15373
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_GSK J1_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0244682
heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
PMC9585487-NIHMS1838959-supplement-4.xlsx-FOXC1-bound_upregulated-Table_S3_FOXC1_regulated_genes_FOXC1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_Triamcinolone Acetonide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138939
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kinase activity	GO Molecular Function Annotations 2015	1.0	null
NCIH838	CCLE Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NB13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-V955-0126-SM-4JBH5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859731
Perturb_4144_KO_Bcl11a/Bcl11b_SRP334609	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.4833
ventral claustrum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1063
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SBC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973587
NDUFA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45431
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68987
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.57001
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19351
stroke	GWASdb SNP-Phenotype Associations	1.0	0.383167
CTCF_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Bosutinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0181612
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TBL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04222
BRD-A01717111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4623
BRD-K02321382	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79358
Celiac disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.509691
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13276
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.437
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3879
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6221-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K51849151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40071
PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39389
BRD-A32018906	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46265
BRD-K38861721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25689
hsa-miR-548z	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K23923189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25866
BRD-K87126326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0754
mp1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
GSE131649_6_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC3960207-oncotarget-05-0264-s002.xls-rank_down_foxp3_symb-Supplementary_Table_2_Genes_significantly_differentially_expressed_between_the_SK-MEL-28-FOXP3_and_SK-MEL-28-EV_clones_FOXP3	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-X6-A8C6-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
purine nucleotide binding	GO Molecular Function Annotations 2015	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7862-01A-21R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K71592817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37973
GTEX-XBED-0526-SM-47JY3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08588
GTEX-P4QR-0426-SM-2S1NV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11
r3 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0852
SGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32608
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	30.3588
NELL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00559977
Perturb_9085_KO_YAP_SRP297717	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K98374711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66136
GSE213588_9_v_6_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_TMP195_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0170733
GTEX-WZTO-0826-SM-3NM8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875584
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0959
RBBP5	ENCODE Transcription Factor Targets	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54599
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_72h_2-down-regulated_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K47200630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91381
Perturb_8901_KD_STIM1_SRP128928	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.52645
BRD-A17741195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77524
BRCA1	ENCODE Transcription Factor Targets	1.0	null
DCAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13947
LMO2-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66873
HUCCT1	DepMap CRISPR Gene Dependency	1.0	2.02816
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56465
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K58846294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00361
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
Egg white	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.629
Brain Lower Grade Glioma_LGG_TCGA-HT-7691-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053571
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126345_4_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Serine/threonine/dual specificity protein kinase, catalytic  domain	InterPro Predicted Protein Domain Annotations	1.0	null
A549_Abexinostat_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0100125
15831697-TableS3	GeneSigDB Published Gene Signatures	1.0	null
consistent	GeneRIF Biological Term Annotations	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45U-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-60-2713-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1475
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.20323
GSE142210_2_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.06
GSE223893_11_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BACH1	ChEA Transcription Factor Targets	1.0	null
novobiocin-na	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19697
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.5094
ventrolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.15185
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CEBPZ_01_75	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.5989
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K35792251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80248
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-11A-13R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55F-1726-SM-2TF4R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962817
lateral trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54503
A549_Azacitidine_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164579
BRD-K50204028_-666_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51061
BRD-K14533399	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48626
MCM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71501
BRD-K26376097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06203
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00638
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.83595
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	2.58839
TTC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53323
BRD-K01297681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.18335
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.434259
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.844154
GSE213588_10_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAFA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4528
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
liver	HPA Tissue Protein Expression Profiles	-1.0	-1.0482
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0826-SM-3GIKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32654
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06463
MEF2A_01_265	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.6716
GSE146982_3_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Essential Tremor	DisGeNET Gene-Disease Associations	1.0	null
GM2493	BioGPS Cell Line Gene Expression Profiles	1.0	0.982142
BRD-K52075040_-666_SKMEL1_6.0_h_44.4_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NANOG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00519568
BRD-K81400584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.47538
BRD-K29838935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.22541
TCEAL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3306
BRD-K94993773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73598
hsa-miR-939	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CRCGN015_MCF10A.TP53.M_24H:M07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.5544
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.864837
r5 part of posteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40949
BRD-K41643612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54174
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE215351,GSE215794_1_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Usp22_DEPLETION_GDS4973_284_mouse_E14 embryonic stem cells (ESCs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01101
layer 1 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.72933
Acute Myeloid Leukemia_LAML_TCGA-AB-2875-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
M14	BioGPS Cell Line Gene Expression Profiles	1.0	1.67855
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859002
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50732
A549_2-Methoxyestradiol_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0116114
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SUPHD1	CCLE Cell Line Gene Mutation Profiles	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Gandotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158546
A549_Droxinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0229654
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H4K20me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00006
abnormality of cerebral artery	GWASdb SNP-Phenotype Associations	1.0	0.300042
TSPOAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00506142
CDC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10878
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03091
BRD-A90131694_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924505
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIN3A_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCK-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.33913
GTEX-WFG7-0726-SM-3GIKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838273
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC10803041-elife-86204-supp2.xlsx-snRNA-seq_Snc-KD_in_HT-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10367
Perturb_15239_KD_ERCC6L2_SRP349996	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.85661
lipoproteins, ldl	GAD Gene-Disease Associations	1.0	null
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WFG8-0001-SM-4LVN8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
A549_Resminostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0211079
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4797
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.41906
BRD-K06489778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77986
abnormality of the skeletal system	GWASdb SNP-Phenotype Associations	1.0	0.056785
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04708
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.666599
GTEX-OHPK-0226-SM-3MJH6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02866
BRD-K69328504_L-690,488_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996421
BRD-K71414336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16235
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.829696
GSE223008_7_v_1_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T2IS-0226-SM-32QPH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34645
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Parkinsonism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral hypothalamic area, mammillary region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30877
BRD-K83670600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80118
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30310008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14269
GSE206984_1_v_0_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE149901_3_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SHKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02251
A549_SRT1720 HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0235406
HDLM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92945
BRD-K22437400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75469
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03572
H3K27me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7023
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5705-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196962_2_v_6_parg_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6923932__F4	PFOCR Pathway Figure Associations 2023	1.0	null
A549_BMS-754807_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154482
ZNF710	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7631
A549_WHI-P154_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0236071
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8739
BRD-K28874552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15639
GSE182680,GSE182683_7_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K40876208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1251
GTEX-X3Y1-0226-SM-3P5Z5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11437
dorsofrontal pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01258
GSE165307_2_v_0_gfi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE195568_3_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OOBJ-1526-SM-3NB1Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01551
thp1	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE261563_9_v_8_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-19a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
CRCGN017_MCF10A.WT.HP_24H:A13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15735
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
evc	GeneRIF Biological Term Annotations	1.0	null
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19494
intermediate stratum of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01094
BRD-K20028734	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30538
UTY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31612
CDK10_knockdown_116_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.78265
GSE182680,GSE182683_7_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ADP	HMDB Metabolites of Enzymes	1.0	null
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53269
CD7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00481173
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE226770_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Dystonia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
trachea	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.385
Posterior pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.20146
without	GeneRIF Biological Term Annotations	1.0	null
BRD-A59943784_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K58310485	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12555
BRD-K86158100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11244
GTEX-NFK9-0926-SM-2HMJU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0495
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.91972
BRD-U37049823_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7617265-EMS137094-supplement-Supplementary_Tables.xlsx-ST18-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213588_10_v_13_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KP3	CCLE Cell Line Gene CNV Profiles	1.0	1.46789
GTEX-TMZS-0001-SM-3P61Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6071
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CB-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_11462_KD_TEAD1/TEAD2/TEAD3/TEAD4_SRP045711	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.4698
BRD-K31059261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02231
superior colliculus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.07472
abnormal bone structure	GWASdb SNP-Phenotype Associations	1.0	0.138221
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06106
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50254
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE198794_0_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.880732
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PH-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
superficial stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07422
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17847
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.928253
GSE101336_1_v_2_decitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-2.8241
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.97326
parkinsonism	GWASdb SNP-Phenotype Associations	1.0	0.487671
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.61706
KYSE70	CCLE Cell Line Gene CNV Profiles	1.0	1.36382
A549_Dasatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126797
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K44027058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59528
Brain Lower Grade Glioma_LGG_TCGA-S9-A89V-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Barasertib_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160596
binding	GO Molecular Function Annotations 2015	1.0	null
GSE256181_2_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
inner CP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.855292
A549_Quisinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166346
CRCGN017_MCF10A.WT.HP_24H:O08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.1148
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04523
BRD-K64537490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13027
hsa-miR-3173-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GTEX-OIZH-0326-SM-2HMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971689
bilirubin metabolic disorder	GWASdb SNP-Disease Associations	1.0	0.840288
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE237040_6_v_1_notch3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-REY6-1226-SM-48FDR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26435
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SB-01A-31R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26758344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37824
u2197	HPA Cell Line Gene Expression Profiles	1.0	1.22859
CD160	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00501587
NCIH1299	CCLE Cell Line Gene CNV Profiles	1.0	1.34061
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-1.0482
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QLQ7-1626-SM-2S1R8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900058
USP49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16208
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
P30OHK	DepMap CRISPR Gene Dependency	1.0	4.30312
BRD-K33897007	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79964
Lung squamous cell carcinoma_LUSC_TCGA-22-4609-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.38093
BRD-A75931230_7706-0139_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RCOR3-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC12368524-Supplementary_materials.pdf-13-ZNF256_transcript_variant_2_ZNF256	Rummagene Transcription Factor Associations 2026	1.0	null
CHP212	CCLE Cell Line Gene Mutation Profiles	1.0	null
SOX9_01_308	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59142
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44708
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11008696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.28048
GSE123943_1_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TE10	CCLE Cell Line Gene CNV Profiles	-1.0	-2.03605
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Electrocardiographic conduction measures	GWAS Catalog SNP-Phenotype Associations	1.0	0.129504
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.93727
H3K56ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13144
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
BRD-A23955117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34394
PMC7304190-13229_2020_355_MOESM18_ESM.xlsx-Supplemental_Table_5-hNSCs_SATB2_SATB2	Rummagene Transcription Factor Associations 2026	1.0	null
mouth	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.277197
FGFR3_knockdown_174_GSE41035	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-3.11115
GTEX-N7MS-0011-R4a-SM-2HMKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909228
18631401-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6520398-41467_2019_10148_MOESM11_ESM.xls-FigS1a-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S11-DUX4_DiffExprGene-Unnamed_1_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8423-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10395
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19061
A549_S3I-201_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0234197
TUBB6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00429018
BRD-K50603336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49585
GSE77108_5_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE148252_7_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
comprising	GeneRIF Biological Term Annotations	1.0	null
posteroventral (inferior) parietal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.68955
GSE219274,GSE219276_2_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K34228325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50377
GSE118816_0_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58689
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
autoimmune disease of gastrointestinal tract	GWASdb SNP-Disease Associations	1.0	0.986376
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ezh2_Deficiency_GDS4309_364_mouse_Hearts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K75506133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31354
CHL-1	GDSC Cell Line Gene Expression Profiles	1.0	2.27284
CHMP1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00417167
BRD-K39159284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94629
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-F_48h_1-Unnamed_0_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
MAPKAPK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00256926
GSE233183,GSE233187_2_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S4Q7-0726-SM-4AD5F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864014
A549_XAV-939_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0320065
substantia nigra reticulata, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43479
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.43104
GSE152441,GSE152442_6_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE218580_1_v_3_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HG3	DepMap CRISPR Gene Dependency	1.0	3.25827
TO175T	CCLE Cell Line Gene Expression Profiles	1.0	1.73668
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K37479727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42756
BRD-A27422067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74516
BRD-K19534880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25818
Hemochromatosis type 2A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.232
BRD-K22420708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0288
GTEX-T5JW-0003-SM-3NMAD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.1376
GSE60217_1_v_8_inosine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-REY6-2426-SM-48FF5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830377
ANKRD50	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00413356
GTEX-RUSQ-0126-SM-47JWV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860405
RIMS4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00485031
striatum_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.905085
SNU-601	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.63068
Metastatic Melanoma	DisGeNET Gene-Disease Associations	1.0	null
intermediate part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05433
r2 part of anteroventral cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37507
Sarcoma_SARC_TCGA-WK-A8XQ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
four	GeneRIF Biological Term Annotations	1.0	null
GSE168797_2_v_3_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of r2BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28577
A549_AZ 960_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0196435
BRD-K26195700	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8775
Perturb_14556_KO_KLF5_SRP051606	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
A549_BMS-911543_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0178697
intermediate stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29391
PMC9305137-PATH-256-297-s005.xlsx-CIC_associated_DE_genes_IDH1-W-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_14667_KO_Sirt3_SRP277814	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.97947
BRD-K26335565	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51062
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871886
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01345
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05578
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28699
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.08916
GSE101112_6_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.913928
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0005
CTCF_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_8_v_11_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.98456
hsa-miR-1252	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
496100330_PCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.10435
RIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04
r6 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2455
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18591
ATG2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36048
r5 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10183
KDM5B_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intelligence	GeneRIF Biological Term Annotations	1.0	null
GTEX-WFG7-0326-SM-3GILI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28174
BRD-K98223571	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.43804
A549_Aurora A Inhibitor I_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016144
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO800	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57679
Oliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.897
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Essential tremor	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
GTEX-XBED-2326-SM-47JYR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861762
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11945
GSE135030_11_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K64091938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89963
intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.374809
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAPK14_knockdown_101_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.72887
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JAG1_OE_GDS3571_40_human_endometrial stromal cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5102-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Mocetinostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0170229
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.17612
H3K27me3_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BCL2L10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84519
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Utricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.856
GSE203429_0_v_1_angptl8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8635809-Table_2.xls-LPS-upregulated-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Oligospermia	CTD Gene-Disease Associations	1.0	1.17101
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
protein serine/threonine kinase activity	GO Molecular Function Annotations 2025	1.0	null
CHP-212	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.11365
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE155836,GSE155839_3_v_2_alvocidib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12621392-12864_2025_12212_MOESM2_ESM.xlsx-GSF-S_48h_2-down-regulated_PDX1	Rummagene Transcription Factor Associations 2026	1.0	null
purine nucleoside binding	GO Molecular Function Annotations 2015	1.0	null
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A195-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1345
CEACAM5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00543864
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69405
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52159
Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31490008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40124
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11474
Mesothelioma_MESO_TCGA-MQ-A4KX-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216273,GSE216292_14_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31037
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_Abexinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129489
GTEX-XPT6-0126-SM-4B65S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08363
GTEX-P4QT-2626-SM-2I3FM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863236
GSE162892_4_v_2_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950706
PFSK-1	GDSC Cell Line Gene Expression Profiles	1.0	2.36139
CENPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05055
BRD-K71544970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12105
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835693
BRD-K63299476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0
PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-x_LPS-BMDCs-kinase_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.476792
GSE242367_1_v_0_dpp9_human	RummaGEO Gene Perturbation Signatures	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01549	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.982811
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.897618
BRD-K71605668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05363
GSE206516,GSE206518_2_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
BRD-A85860691_chaetocin_A375_24.0_h_0.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2BK120ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
orbital frontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.918069
BRD-A17687311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01811
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.80553
paresthesia	GWASdb SNP-Phenotype Associations	1.0	0.882984
Retrosplenial area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22455
CAOV3	CCLE Cell Line Gene CNV Profiles	1.0	1.74891
H3K4me1_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CCNC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00840653
BRD-K98117883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18811
A549_Tie2 kinase inhibitor_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0191343
GSE210655_1_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-U3ZN-2026-SM-4DXUC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949068
PMC6344081-elife-40364-supp8.xlsx-PLZF-Si-diff-expressed-gen-Down-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K66879977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60789
hsa-miR-3662	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K61386375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53232
PMC12661646-dmm-18-052290-TableS5.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G2_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63063
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:H09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.90685
Acute Myeloid Leukemia_LAML_TCGA-AB-2937-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196259_2_v_0_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10196668	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95281
Protein kinase domain	InterPro Predicted Protein Domain Annotations	1.0	null
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.91559
A549_Resveratrol_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.018337
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE128844_0_v_1_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-557	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE77108_4_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.7863
GSE162892_4_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RH-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cognitive impairment	GWASdb SNP-Phenotype Associations	1.0	0.522136
CDIPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66907
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.94789
20174566-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE138672_4_v_3_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary visual cortex (striate cortex, area V1/17)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23151
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94621
BRD-K05153001_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K67835515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0105
GTEX-TKQ1-0126-SM-33HB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0206
Perturb_4636_KO_lnc956_SRP359638	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
A549_Ofloxacin_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0129781
physical disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.230063
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48747
A549_Mocetinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150781
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Obatoclax Mesylate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145657
C6orf120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22154
anterior (rostral) cingulate (medial prefrontal) cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39457
GSE195503_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKMEL1	CCLE Cell Line Gene Expression Profiles	1.0	2.4099
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE101112_0_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4492	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
TBCD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92253
Ellis-Van Creveld Syndrome	DisGeNET Gene-Disease Associations	1.0	null
GTEX-R3RS-0626-SM-48FE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04632
MXI1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3184	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
MCM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17763
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
alzheimer's disease	GWASdb SNP-Disease Associations	1.0	1.24194
GSE184087_4_v_1_tert_human	RummaGEO Gene Perturbation Signatures	1.0	null
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.400838
CRCGN011_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12985
BRD-K28140275	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19413
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oral squamous cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.20422
A549_Iniparib_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151923
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.8534
Primary hematopoietic stem cells G-CSF-mobilized Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.56409
GSE233679_6_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.857186
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.258597
r4 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24817
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.412122
Pia mater	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.555
protein phosphorylation	GO Biological Process Annotations 2023	1.0	null
MHHCALL4	CCLE Cell Line Gene Expression Profiles	1.0	1.57698
BRD-K58827489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.86362
developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.209583
primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.870612
HNF4 direct repeat 1	MotifMap Predicted Transcription Factor Targets	1.0	null
LN18	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.877711
A549_ITSA-1_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130827
substance dependence	GWASdb SNP-Disease Associations	1.0	0.390579
GSE77108_3_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE218727_2_v_1_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Generalized Anxiety Disorder	DisGeNET Gene-Disease Associations	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE228894_0_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_MC1568_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0340431
orbital frontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2831
MZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.895467
Perturb_14675_KO_RpL13a_SRP090469	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.45156
GSE140997_4_v_6_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q734-0526-SM-2I3EH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.867832
GTEX-W5X1-2326-SM-3GIL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27047
BRD-K19776718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07774
MZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69803
BRD-K52175660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87306
BRD-A75172220_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
prdm1_21670299_e18dot5_small_intestine_lof_mouse_gpl6887_gse29658	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.605293
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.11874
CRCGN016_MCF10A.TP53.M_24H:J11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.58253
GTEX-SJXC-0226-SM-2XCDU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03387
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146982_4_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE211126_3_v_0_hapln1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Ki8751_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0361277
A549_PFI-1_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0129933
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32459
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.710116
BRD-K25757224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37793
FASTKD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00457802
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-d-Classification_of_camel_SON_basal_genes_-_enzymes_SON	Rummagene Transcription Factor Associations 2026	1.0	null
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	0.921866
GSE242083,GSE242098_3_v_5_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58923
hsa-miR-3685	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.084
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.212133
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.949679
GSE213588_10_v_5_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8206-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JHOM2B	CCLE Cell Line Gene Mutation Profiles	1.0	null
TXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03132
G124	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.887147
POLR2A	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MKN1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.57815
GSE174406_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HS578T	BioGPS Cell Line Gene Expression Profiles	1.0	1.0603
GTEX-R53T-0326-SM-48FEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96551
PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10769395-media-2.xlsx-S2D_EF_Repressed_genes-Ebegboni_et_al_Supplemental_Table_S2D_Increased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.353
AK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00596962
BRD-K06500446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06862
PYGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23845
A549_MLN8054_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0113298
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3M_Peaks_YAP1MAMLD1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28859
SNU16	CCLE Cell Line Gene CNV Profiles	-1.0	-2.52942
BRD-K65733046	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95081
VZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02213
hsa-miR-3170	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07025
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_02_196	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.6116
intermediate part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6273
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5514
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39425
GSE235550_2_v_0_hspa9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128634,GSE128636_2_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231799_3_v_4_nfkbie_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Main olfactory bulb, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01862
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3619-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
TMEM42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42305
primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.839761
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26415
H3K27me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.1467
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mucopolysaccharidosis I	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
BRD-A35108200_betamethasone_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01295
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1876
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SISO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE221004_3_v_2_prdm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE153871_1_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE96649_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78789413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.16034
CD56+_NKCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.32213
BRD-K58324650	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12925
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6797-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_TBX3_20139965	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
phosphorus metabolic process	GO Biological Process Annotations 2015	1.0	null
A549_Tie2 kinase inhibitor_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.038091
A549_Costunolide_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0231604
RAB40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10475
protein modification process	GO Biological Process Annotations 2015	1.0	null
BRD-K90408478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95221
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15473
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65739
GTEX-REY6-0526-SM-2TF5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59058
GSE174498,GSE174500_3_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Roxadustat_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0219132
GSE256181_1_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57398
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5F-Up_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K74712962	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01503
496100550_TCx_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11279
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HP-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
GTEX-T5JC-0001-SM-3NMAK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56375
EPB41L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47764
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.77704
hypersensitivity reaction type ii disease	GWASdb SNP-Disease Associations	1.0	0.165872
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	1.271
lateral part of CoP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26102
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K66707905	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.542
dorsomedial part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03356
Necrosis	CTD Gene-Disease Associations	1.0	1.10388
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47381
GTEX-QDVN-0626-SM-2I3FP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02924
SOX2-27498859-CHIP-SEQ-STOMACH-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lateral habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25312
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K43594798	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9564
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.866444
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MB-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A98795688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05831
BRD-K43341819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23168
PMC6683136-41598_2019_47363_MOESM4_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K82446079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17392
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01314849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50492
BRD-K60389305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06688
BRD-K51498205	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00247
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.29141
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957602
A549_Decitabine_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0111253
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3N_Peaks_YAP1FAM118B_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.969984
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
A4FUK	CCLE Cell Line Gene CNV Profiles	1.0	1.91333
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-2026-SM-447BI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47216
Perturb_6169_KD_PROX1_SRP073100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.47677
CRCGN014_HEPG2_24H:I18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28767
spleen_3b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.0006
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76478
A549_Cyclocytidine HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0093264
CRCGN016_MCF10A.TP53.M_24H:I11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8573
ellis-van creveld syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.46495
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47429
GSE109565_12_v_11_glyphosate_human	RummaGEO Drug Perturbation Signatures	1.0	null
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56309
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06997715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07471
Coronary Heart Disease	DisGeNET Gene-Disease Associations	1.0	null
dorsolateral prefrontal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5274
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
IGR39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49393
GSE248045,GSE248046_4_v_2_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SKP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00781272
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Anacardic Acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0229762
r3 part of cochlear sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26551
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23741
PSMB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11661
SRR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00457954
Bone development disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.042
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSKH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00609967
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16985
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:F04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13313
lateral hypothalamic area, anterior region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.30701
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
19843711-TableS2	GeneSigDB Published Gene Signatures	1.0	null
BRD-K81515704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12175
Developmental and epileptic encephalopathy 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.626
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
18310505-TableS7	GeneSigDB Published Gene Signatures	1.0	null
BRD-K63401195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22218
primary motor cortex (area M1, area 4)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12502
lateral spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1869
BRD-A22707317_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K28912195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70821
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2148
kidney_b	HPA Tissue Sample Gene Expression Profiles	1.0	1.18347
GTEX-SIU8-0226-SM-2XCDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25268
RAD21_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85266
GP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00465118
A549_Tozasertib_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144384
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	1.0	4.87811
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.835518
HL60	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.08878
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.845739
GTEX-OHPM-0226-SM-3LK61	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953107
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_3Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.67221
ZNF384	ENCODE Transcription Factor Targets	1.0	null
PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S12-ZNF384_DiffExprGene-Unnamed_1_ZNF384	Rummagene Transcription Factor Associations 2026	1.0	null
doxorubicin_homo sapiens_gpl10558_gse42531	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE146982_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90713
elements	GeneRIF Biological Term Annotations	1.0	null
GTEX-W5X1-0001-SM-3P61V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67694
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.TP53.M_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.22231
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A57E-11A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
purine ribonucleotide binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-POMQ-0826-SM-3P61H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07537
recombination	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4267	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.51199
Linear nucleus of the medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45376
H2BK15ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	1.16913
Lung squamous cell carcinoma_LUSC_TCGA-94-A5I6-01A-21R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF4-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
A549_Resveratrol_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126282
BRD-A52475911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54514
Perturb_17663_KD_TRAF4_SRP292631	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP2K1_knockdown_105_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.63275
CTCF_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64052750_gefitinib_BT20_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A549_EED226_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0191536
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890726
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4487811-mmc3.xlsx-siRE_enriched_geneLists-siRE_occupancy_pattern_gene_lists_after_RUNX1_ETO_knock_down_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
A253	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
GTEX-SE5C-0626-SM-2XCDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934557
BRD-K69984954	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61754
L540	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46433
dorsal part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13056
GSE140997_10_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149359_2_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24674
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6941-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13876_OE_ABCC1_SRP301382	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K40612106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12996
GSE168797_1_v_3_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
r3 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30936
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE224311_3_v_4_chaetocin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51697
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K16570418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03979
GSE244072_10_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.317
BRD-K47438870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39731
GSE228727_2_v_0_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.77298
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_3_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9980149-media-17.xlsx-Supp_Table_12_Bulk_Seq_CTH_KD_I-SUPPLEMENTARY_TABLE_12_Bulk_RNA-seq_results_of_invasive_fractions_from_GBM43_CTH_knockdwn_vs_GBM43_control_cells_invading_3D_hydrogels_AR	Rummagene Transcription Factor Associations 2026	1.0	null
OVKATE	CCLE Cell Line Gene CNV Profiles	1.0	1.66267
GSE189653,GSE203344_5_v_3_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A69951442_dexamethasone_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_SNS-314 Mesylate_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154579
evc2	GeneRIF Biological Term Annotations	1.0	null
BRD-K51241952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30014
16141321-Table2	GeneSigDB Published Gene Signatures	1.0	null
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
palate	GeneRIF Biological Term Annotations	1.0	null
PMC4609150-13073_2015_228_MOESM2_ESM.xlsx-TP53-Gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
STAT3_01_334	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.03967
GSE182680,GSE182683_5_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10794847-mmc5.xlsx-PIAS1_KD_down-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A40504327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26146
GSE148252_7_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
r5 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29462
GSE164874_5_v_7_prednisolone_human	RummaGEO Drug Perturbation Signatures	1.0	null
bone disease	GWASdb SNP-Disease Associations	1.0	0.140548
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77612
BRD-K56562541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23901
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11993713-41598_2025_96655_MOESM1_ESM.xlsx-S10-Table_S10_MR_results_of_the_discovery_blood_cis-eQTLs_and_Sepsis_outcomes_in_IVW_or_Wald_ratio_methods_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146982_3_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
A549_ITSA-1_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152018
PMC8528285-pbio.3001085.s010.xlsx-Fig_8C-MLX_3T3_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE101239_5_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.920777
hl60	HPA Cell Line Gene Expression Profiles	-1.0	-0.894171
GSE127790_4_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216147_2_v_1_rbm20_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835246
mRNA_MSC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE233679_12_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
19429869-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-OHPM-1826-SM-2YUNF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995173
Acute Myeloid Leukemia_LAML_TCGA-AB-2817-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE213588_8_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Serine/threonine-protein kinase, active site	InterPro Predicted Protein Domain Annotations	1.0	null
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48747
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
morphological abnormality of the central nervous system	GWASdb SNP-Phenotype Associations	1.0	0.177283
Lake et al.Science.In7_Brain_Human	CellMarker Gene-Cell Type Associations	1.0	null
COLO201	CCLE Cell Line Gene CNV Profiles	-1.0	-1.8646
BRD-K88831197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.63217
GTEX-T6MO-0003-SM-3NMAG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43474
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0393
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2899-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-214	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_11_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
granulomatosis	GWASdb SNP-Phenotype Associations	1.0	0.320236
BRD-K90918886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30562
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.984695
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.80547
SNU738	CCLE Cell Line Gene CNV Profiles	-1.0	-2.20049
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE86507,GSE86509_7_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEx Ovary 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	-1.0	-7.44616
GTEX-XBED-1626-SM-47JYN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20191
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49112
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	1.674
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29W-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_UNC1999_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0191234
GTEX-XBEC-0326-SM-4AT4M	GTEx Tissue Sample Gene Expression Profiles	1.0	2.01395
MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE2779	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.43839
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20257
ACHN	BioGPS Cell Line Gene Expression Profiles	1.0	1.4322
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2347	CCLE Cell Line Gene Mutation Profiles	1.0	null
Perturb_12035_KO_Ccr2_SRP247656	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.7462
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BF-11A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-5332-01A-01R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38083
Perturb_259_KD_PBRM1_SRP358304	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
outer CP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.48253
GSE120612_6_v_0_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE226249_2_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PFSK1	DepMap CRISPR Gene Dependency	1.0	2.24599
GTEX-XPVG-0726-SM-4B658	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20913
Supramolecular complex	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
MT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45334
H3K4me1_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K56ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_Clevudine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166343
WTAP_KD_GDS2010_69_human_HUVEC (umbilical vein endothelial cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K34026318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88893
BRD-K58688519	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60354
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.117
GTEX-XYKS-2726-SM-4E3IC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861529
Human - Fetal Development - L2 - Stomach-Vascular endothelial cells	HuBMAP Azimuth Cell Type Annotations	1.0	null
r7 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49145
GSE135030_3_v_7_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Diffusing capacity of the lung for carbon monoxide traits	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.622185
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869157
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_UNC0631_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130565
GSE135030_11_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_MC1568_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.019133
ZFAND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04808
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CYP2A6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00463595
movement disease	GWASdb SNP-Disease Associations	1.0	0.435368
BRD-K89811208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05137
ARH-77	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE135030_11_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_MLN8054_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172719
TP53	ChEA Transcription Factor Targets	1.0	null
abnormality of immune serum protein physiology	GWASdb SNP-Phenotype Associations	1.0	0.621289
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Fetal akinesia deformation sequence syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.151
RPL13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08415
hypersensitivity reaction type iv disease	GWASdb SNP-Disease Associations	1.0	0.609395
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RT-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12661646-dmm-18-052290-TableS7.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196104,GSE196106_2_v_0_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A1HT-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_HEPG2_48H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12355
Frontal pole, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14362
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53606
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.574776
GSE195568_6_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cleft Lip With Or Without Cleft Palate	DisGeNET Gene-Disease Associations	1.0	null
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36251
cuneus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4223
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.939042
inferior olivary complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.874205
Supplemental somatosensory area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24706
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57917
Generalized anxiety disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
UBXN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74069
A549_Danusertib_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162168
IRF6_01_101	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.65073
Pancreatic alpha cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.018
GTEX-Q734-0326-SM-48U15	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13743
Brain Lower Grade Glioma_LGG_TCGA-DU-A7T6-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL6-25482012-CML-JURL-MK1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
inherited metabolic disorder	GWASdb SNP-Disease Associations	1.0	0.199318
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3647-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
NCIH358	DepMap CRISPR Gene Dependency	1.0	2.80044
BRD-K95323755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56405
CRCGN009_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.96454
OXA1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42436
GSE172189_0_v_1_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A45607610	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26854
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
18381933-SuppTableS4	GeneSigDB Published Gene Signatures	1.0	null
Lake et al.Science.Ex8_Brain_Human	CellMarker Gene-Cell Type Associations	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX3-20139965-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4728-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28524
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.827833
BRD-K96817767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13796
GTEX-OXRL-1626-SM-2YUMU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.855783
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52301
GTEX-OOBJ-0226-SM-2YUMM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912347
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41376
Alzheimer's disease progression score	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.569897
A549_JQ1_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169715
BRD-K02517738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3581
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XOT4-0726-SM-4GIAW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845862
A549_GSK1070916_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0152197
SUZ12	ChEA Transcription Factor Targets	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
A549_Celecoxib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154581
reticular formation of CoPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03315
MAST2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00439078
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13
SUZ12-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.400838
BRD-K16966765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28765
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60514
BRD-K74688087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96033
BRD-K07365255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33505
GSE119978,GSE180930_2_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Fulvestrant_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151729
BRD-A07407288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63503
GSE173232_2_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_4_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K33864865_LY 225910_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Spleen	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.65978
ischemic stroke	GWASdb SNP-Phenotype Associations	1.0	0.636183
A549_Pelitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157082
BRD-K38694430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26343
GSE180468_3_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.98514
type ii diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.540725
BRD-K44705560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.14895
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_0_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10721704-12265_2022_10347_MOESM9_ESM.xlsx-S6B-Supplementary_Table_6B_Region_level_burden_tests_variants_with_MAF_0_01_only_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tauopathy	GWASdb SNP-Disease Associations	1.0	1.24194
A549_TMP195_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015109
HS863T	CCLE Cell Line Gene Expression Profiles	1.0	2.02155
GSE152441,GSE152442_7_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138001_5_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12318984-Table1.xlsx-S7-Table_S7_Instrumental_variables_IVs_identified_from_eQTL_dataset_for_druggable_GIKs_used_in_Mendelian_randomization_MR_analysis_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K46124507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36572
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66461
Lung squamous cell carcinoma_LUSC_TCGA-92-8063-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EWSR1_KD_GDS4962_469_human_Ewing sarcoma and prostate cancer	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K07770425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35458
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.963662
VZ in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04257
496100599_TCx_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21304
PMC7041704-JEM_20180649_TableS1.xlsx-shared_LPS_downregulated_genes-Unnamed_6_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K60937893	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46499
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8766486-42003_2021_2990_MOESM3_ESM.xlsx-ST18-Supplementary_Data_18_Gene_burden_for_deletions_by_subtype_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39361
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39653
central gray substance of midbrain, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.936465
A-Netherlands-602-2009(H1N1)_3Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.93256
BRD-K07825644	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04679
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE162892_4_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_BMS-911543_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0129112
GTEX-X4XY-0926-SM-4E3JD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835346
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27862
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YQ-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195568_2_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Micronuclei, Chromosome-Defective	CTD Gene-Disease Associations	1.0	1.33052
parkinson's disease	GWASdb SNP-Disease Associations	1.0	0.572462
GTEX-XK95-0426-SM-4AT4R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855976
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RV-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_5_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
abnormality of extrapyramidal motor function	GWASdb SNP-Phenotype Associations	1.0	0.487671
primary visual cortex (striate cortex, area V1/17)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.89426
BRD-K98145661	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04869
Perturb_12647_KD_Dirc3_SRP191022	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MITF	ChEA Transcription Factor Targets	1.0	null
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	-1.0	null
type 2 diabetes mellitus	GWASdb SNP-Disease Associations	1.0	2.26415
YTHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42542
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K71817857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47873
GSE178907_5_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_11601_KD_ABCD4_SRP113334	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.20791
E2F4	ENCODE Transcription Factor Targets	1.0	null
HCC366	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984285
WM115	CCLE Cell Line Gene Expression Profiles	1.0	2.35338
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_Tie2 kinase inhibitor_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0185483
A204	BioGPS Cell Line Gene Expression Profiles	1.0	2.41625
19843711-TableS1	GeneSigDB Published Gene Signatures	1.0	null
BHLHE40_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Essential tremor	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.648
HT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.45753
GTEX-WL46-0326-SM-3LK6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60451
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-7021-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE118077_7_v_8_sprr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HI-7168-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
17880687-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3151	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
20140255-TableS1	GeneSigDB Published Gene Signatures	1.0	null
arteriosclerosis	GWASdb SNP-Disease Associations	1.0	0.371104
BRD-K80923834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27345
ChIP_SUZ12_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.955865
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
depression	GWASdb SNP-Phenotype Associations	1.0	0.387866
BRD-K66717300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.12109
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04282
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.191
GSE139948_3_v_6_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2886-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100435_TCx_probable Alzheimer's disease_TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24263
A549_Luminespib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144065
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830944
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.21992
H4K20me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07468
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_SRT3025 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0205417
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K68635551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10938
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OPM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00085
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.32682
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.8333
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903391
SARS-CoV MA15_Day2-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.57238
Superior temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.696
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44603
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06322
IST-MEL1	GDSC Cell Line Gene Expression Profiles	1.0	1.75398
A549_Tazemetostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157438
COMPOUND 74 [PMID: 24793884]	DGIdb Drug Targets 2026	1.0	8.822
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29763
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FCGR3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0049899
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19752998	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09784
BRD-K27754030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13406
RCOR1	ENCODE Transcription Factor Targets	1.0	null
GSE94814_2_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ARHGEF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09546
GSE155972_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r5 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61961
hsa-miR-544	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
DEPDC5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00459684
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.113
GSE182680,GSE182683_7_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE87617_1_v_0_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K31917106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77594
BRD-K36807301	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04213
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE120612_7_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-19b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
A549_Mercaptopurine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0234715
NCI-H2347	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92493
GTEX-X3Y1-0426-SM-3P5Z4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51041
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain_CT2_DLIT 152	HuBMAP ASCT+B Annotations	1.0	null
MSTO211H	DepMap CRISPR Gene Dependency	1.0	10.2679
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66564
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE116930,GSE116935_1_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
outer CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.987239
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29467
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-0526-SM-4B65N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09863
squamous epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09935
RT112	CCLE Cell Line Gene CNV Profiles	1.0	1.52431
EGR1	ENCODE Transcription Factor Targets	1.0	null
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_PD173074_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0229947
CTCF_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242367_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7583-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OXRK-0826-SM-2HMK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42426
GSE214931_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of eye movement	GWASdb SNP-Phenotype Associations	1.0	0.556012
Sarcoma_SARC_TCGA-IF-A4AK-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19008
cuneiform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40584
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE224004,GSE224005_0_v_8_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-K1-A6RU-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-toNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13233
Vascular endothelial growth factor levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.930103
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09355
abnormality of higher mental function	GWASdb SNP-Phenotype Associations	1.0	0.360468
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19221
BRD-K05402890_NCGC00165289-01_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SW837	DepMap CRISPR Gene Dependency	1.0	2.49437
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25294
PIR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00582072
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925208
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
BRD-K82968130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35008
RPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72822
PSIP1_Deficiency_GDS2883_633_human_T-cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-3158-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91856
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vagina	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.566358
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
RAD21_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934045
NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
MAGT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00508706
MAFK	ENCODE Transcription Factor Targets	1.0	null
BRD-K75606012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05454
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.6492
GSE233679_12_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K84769529	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35958
GTEX-S33H-1626-SM-4AD68	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899121
GTEX-P78B-1826-SM-3P5YX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874022
TAK-715	LINCS KinomeScan Kinase Inhibitor Targets	1.0	0.944052
BRD-K65633211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09637
A549_MLN8054_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0176892
PANC 02.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00085
A549_Danusertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145996
RNF186	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00644568
orbital frontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.834319
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25301
BRD-K13089873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01202
substance-related disorder	GWASdb SNP-Disease Associations	1.0	0.26468
BRD-K94441949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.59185
BRD-A92439610_TRIAMCINOLONE ACETONIDE_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43877
STAT1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K83942575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75063
ME1	CCLE Cell Line Gene Expression Profiles	1.0	1.53793
BRD-K95729740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49527
GSE248045,GSE248046_4_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Ki8751_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144439
Fetal_Brain_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.935245
A549_PF-3845_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175723
A549_2-Methoxyestradiol_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171474
BFTC-909	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7103-01A-21R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE77108_5_v_7_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Brain_CT2_Splat 421	HuBMAP ASCT+B Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BX-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87251
cellular process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-3658	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.0526
RT112	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48802
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE168797_1_v_6_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27152
QPCT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0045659
BRD-K60068268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19814
A549_ABT-737_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171755
BRD-K07420629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00087
A549_Cyclocytidine HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0204365
Ahr::Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.625
KDM5A	ENCODE Transcription Factor Targets	1.0	null
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04593
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spinal nucleus of the trigeminal, oral part, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50837
ZNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22145
RB1_KD_GSE50532_591_human_OSTEOBLASTS	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
BRD-K36778976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4739
Perturb_6940_KO_Rbm20_SRP403612	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.39803
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Goldenhar syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.326
Fetal Growth Retardation	CTD Gene-Disease Associations	1.0	1.14098
PMC12661646-dmm-18-052290-TableS9.xlsx-Table_S7_related_to_Fig5D-Fig_5D_-_overlap_between_genes_differentially_expressed_in_presence_absence_of_FOXP2_with_cerebellar_organoid_data_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K31093279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15729
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24797
GSE138001_2_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30331
HOXB4_induction_GDS3036_138_mouse_ES cell-derived embryoid bodies (EBs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.504
m2 part of substantia nigra compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06286
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65823
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CCR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00780189
Perturb_6254_KO_CIC_ERP108370	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
XBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10928
GSE226770_1_v_6_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KRAS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00490823
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42286
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28995
BRD-K37532736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07246
GSE196671_6_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7SF-0001-SM-3K2BE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61159
GTEX-XV7Q-1326-SM-4BRWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09873
SNAI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42526
GTEX-U3ZM-0002-SM-3NMDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56209
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5237
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.18302
PMC6242972-41467_2018_6699_MOESM5_ESM.xlsx-Sheet1-Supplementary_Data_2_Significantly_up-_and_down-regulated_genes_adj_P_Val_0_05_upon_TBX2_knockdown_in_the_IMR-5_75_cell_line_TBX2	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Enzastaurin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0238286
CRCGN015_MCF10A_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00518
BRD-K02471501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12822
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K86978618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9006
A549_Regorafenib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153981
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.849097
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49188
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stomach	HPA Tissue Gene Expression Profiles	1.0	1.14728
GTEX-QDT8-0226-SM-32PL4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00545
BRD-K49473928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15122
diagnosed	GeneRIF Biological Term Annotations	1.0	null
BRD-K76450502	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.97138
primary visual cortex (striate cortex, area V1/17)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25765
GSE148657_3_v_1_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.884859
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44413
Perturb_6974_KO_Acsl1_SRP117680	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.79749
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91267
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of skeletal morphology	GWASdb SNP-Phenotype Associations	1.0	0.062537
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A4CL-01A-41R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE261563_0_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RH-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A27693633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00981
Lung squamous cell carcinoma_LUSC_TCGA-85-7950-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07411
TGFBR1_activemutant_291_GSE14523	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.65878
CRCGN015_HEPG2_48H:L04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04635
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210911_1_v_0_crem_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6932815-ppat.1007634.s015.xlsx-ST5_DGE_ELF1-R8AvIFN48-mock_lfc-ensembl_gene_id_ELF1	Rummagene Transcription Factor Associations 2026	1.0	null
lateral subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06132
mantle zone of r6BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.21064
A549_JNJ-7706621_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0185953
16651414-Supp2	GeneSigDB Published Gene Signatures	1.0	null
PCM6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34774
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
peptidyl-serine modification	GO Biological Process Annotations 2023	1.0	null
BRD-K22478004	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51506
Lung adenocarcinoma_LUAD_TCGA-69-7973-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
outer SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16585
BRD-K86630280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16055
GSE215351,GSE215794_1_v_3_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5691083-41467_2017_859_MOESM6_ESM.xlsx-FDR_0_1_RELB_RNAi-Unnamed_1_RELB	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A89354030	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15728
Perturb_1109_KO_Nkx2_SRP032537	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.1673
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K20661169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0914
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.71383
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ewing's family tumor cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.699
cation binding	GO Molecular Function Annotations 2015	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_1day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.42832
BRD-A83672804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36387
VARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0647
BRD-K77594363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64692
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84609
Lung adenocarcinoma_LUAD_TCGA-95-A4VP-01A-21R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null