association dataset threshold value standardized value H3K4me3_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Jurkat_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null HEI-OC1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.073 Posterolateral visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21999 CREB1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XOTO-0006-SM-4B64T GTEx Tissue Sample Gene Expression Profiles -1.0 -1.43819 CTCF_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE132694,GSE132717_0_v_2_meis1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XAJ8-1326-SM-47JYT GTEx Tissue Sample Gene Expression Profiles 1.0 1.61416 TUBB3 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-SIU7-0006-SM-2XCE6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.916 H3K4me3_foreskin fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null CCNT1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null core of P-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27684 H3K4me2_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.36648 PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL2-Unnamed_0_TAL2 Rummagene Transcription Factor Associations 2026 1.0 null CP in caudal hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.30514 KRT80 Pathway Commons Protein-Protein Interactions 1.0 null Eca-109 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.868 Brain Lower Grade Glioma_LGG_TCGA-DU-5847-01A-11R-1708-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-93 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 UFM1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.82697 PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR Rummagene Transcription Factor Associations 2026 1.0 null CHD2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM12866_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of villous mesenchyme_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Manchette COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.465 MAX_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H820 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.853629 Kidney Chromophobe_KICH_TCGA-KL-8332-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE218819_2_v_1_kdm5b_human RummaGEO Gene Perturbation Signatures -1.0 null DYNC1H1 Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-GN-A4U9-06A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KRT6A Pathway Commons Protein-Protein Interactions 1.0 null CDX2-19796622-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE160304,GSE163392_4_v_3_zswim8_human RummaGEO Gene Perturbation Signatures -1.0 null Lung carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.671 mantle zone of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05242 TBL1XR1 ENCODE Transcription Factor Targets 1.0 null PMC11343843-41540_2024_417_MOESM4_ESM.xlsx-KIN_PHOS-Kinases_or_phosphatases_inferred_with_KSEA_Phosphoscore_or_KSEA_PhosphoScore_in_training_dataset_KIN Rummagene Transcription Factor Associations 2026 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NQ-01A-11R-A27V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Stomach TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040795 POLR2A_HepG2_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anophthalmia And Pulmonary Hypoplasia DisGeNET Gene-Disease Associations 1.0 null SNCA_KO_GDS4153_443_mouse_Striatum - 6 months GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Throat TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GTEX-PW2O-1426-SM-48TCD GTEx Tissue Sample Gene Expression Profiles 1.0 1.78978 GTEX-RM2N-1426-SM-2TF4H GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2558 placenta_3a HPA Tissue Sample Gene Expression Profiles -1.0 -1.41363 GTEX-XXEK-1626-SM-4BRUZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18196 Sarcoma_SARC_TCGA-IS-A3KA-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06124 H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5706-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_bronchial epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null EEF2KMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08473 inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.44839 GTEX-XV7Q-1426-SM-4BRWA GTEx Tissue Sample Gene Expression Profiles 1.0 1.03823 PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Myeloid leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.292 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.42733 fallopiantube_8d HPA Tissue Sample Gene Expression Profiles 1.0 1.5645 SNRPA1 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-UN-AAZ9-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-19b TargetScan Predicted Conserved microRNA Targets 1.0 0.348832 Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver Carcinoma DisGeNET Gene-Disease Associations 1.0 null mediodorsal nucleus of thalamus_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00039 POLR2A_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null metabolic GAD High Level Gene-Disease Associations 1.0 0.303208 Respiratory system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.672 NAT10 Pathway Commons Protein-Protein Interactions 1.0 null Gustatory areas, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.14783 EZH2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT6 MotifMap Predicted Transcription Factor Targets 1.0 null RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.27 Salt gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.518 SMC4 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-WHWD-1826-SM-3LK6I GTEx Tissue Sample Gene Expression Profiles -1.0 -1.22469 SHP77 CCLE Cell Line Gene Mutation Profiles 1.0 null increased fasting circulating glucose level IMPC Knockout Mouse Phenotypes 1.0 null GTEX-X4EP-0826-SM-3P5YK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12238 PSMC2 Pathway Commons Protein-Protein Interactions 1.0 null SP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24968 HDAC1 Pathway Commons Protein-Protein Interactions 1.0 null GR MotifMap Predicted Transcription Factor Targets 1.0 null SIK3 Pathway Commons Protein-Protein Interactions 1.0 null GSE235066_7_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null hsa-miR-520g TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 GTEX-PSDG-0226-SM-33HC1 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 GTEX-Q2AG-0826-SM-2HMKF GTEx Tissue Sample Gene Expression Profiles 1.0 0.990023 H2AFZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_astrocyte of the spinal cord_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PWCY-0005-SM-33HBP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02298 CAL78 CCLE Cell Line Gene CNV Profiles 1.0 1.33467 Moxonidine DeepCoverMOA Drug Mechanisms of Action 1.0 0.27 GSE210842_3_v_1_hnf4a_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_skeletal muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GOLGA2 Pathway Commons Protein-Protein Interactions 1.0 null Body Mass Index dbGAP Gene-Trait Associations 1.0 0.820059 PDPK1 Pathway Commons Protein-Protein Interactions 1.0 null MAX_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Thymus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.962435 H3K27ac_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K27ac_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC9710014-12876_2022_2535_MOESM2_ESM.pdf-44-CSRNP3_CSRNP3 Rummagene Transcription Factor Associations 2026 1.0 null PKN1 Pathway Commons Protein-Protein Interactions 1.0 null Lateral ventricle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ZBTB7A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WH7G-0005-SM-3NMBX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.44229 GTEX-RWSA-2426-SM-47JXR GTEx Tissue Sample Gene Expression Profiles 1.0 1.70893 parabigeminal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.834097 GSE112763,GSE112767_4_v_1_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.984984 IPO7 Pathway Commons Protein-Protein Interactions 1.0 null A549_CUDC-907_100nM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0172378 DYNC1LI1 Pathway Commons Protein-Protein Interactions 1.0 null VZ in subgenual cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.959802 GSE110268_2_v_3_foxd1_human RummaGEO Gene Perturbation Signatures -1.0 null PMC10709143-41556_2023_1271_MOESM9_ESM.xls-Up_in_PAX7--Target_name_PAX7 Rummagene Transcription Factor Associations 2026 1.0 null superficial stratum of PCPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20825 GSE200839,GSE233826_3_v_6_tnrc18_human RummaGEO Gene Perturbation Signatures 1.0 null ZNF766 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1816 Pancreatic Ductal Adenocarcinoma DisGeNET Gene-Disease Associations 1.0 null Piriform area, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20538 abnormality of the systemic arterial tree GWASdb SNP-Phenotype Associations 1.0 0.131115 GTEX-WFJO-0226-SM-3GIKW GTEx Tissue Sample Gene Expression Profiles 1.0 0.921267 brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.078833 overnutrition DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.256228 SUDHL6 CCLE Cell Line Gene CNV Profiles 1.0 1.38466 cytoplasm LOCATE Predicted Protein Localization Annotations 1.0 null NR2F2_02_19 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.27302 Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DM-01A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SJSA1 CCLE Cell Line Gene CNV Profiles -1.0 -1.50478 CUX1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-TMMY-0005-SM-33HBN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.28773 STAT3-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null FBXL18 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.58022 POLR2A_GM12892_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE157960_2_v_3_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null Prostate adenocarcinoma_PRAD_TCGA-VN-A88L-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ELAVL1 Pathway Commons Protein-Protein Interactions 1.0 null PSMD1 Pathway Commons Protein-Protein Interactions 1.0 null Disease of cellular proliferation DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.905 fallopian tube HPA Tissue Protein Expression Profiles 1.0 0.857749 Colorectal Carcinoma DisGeNET Gene-Disease Associations 1.0 null nucleus of the inferior collicular brachium, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79655 Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.86246 PHA-767491 LINCS KinomeScan Kinase Inhibitor Targets 1.0 0.959553 MRE11A Pathway Commons Protein-Protein Interactions 1.0 null Tyrosinemia type III DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.034 posteroventral (inferior) parietal cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.873466 POLR2A_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null caudal ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.91192 A549_CUDC-907_10nM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0159687 H3K4me1_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Dorsomedial nucleus of the hypothalamus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62508 Zic1::Zic2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.7829 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-x_LPS-BMDCs-kinase_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null NCIH1650 CCLE Cell Line Gene CNV Profiles -1.0 -1.65241 TFAP2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 133.729 medial preoptic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23948 NPDC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49181 chr11_8519232_G_T_b38 GTEx eQTL 2025 1.0 1.77652 CTCF_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null periventricular stratum of isBL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15427 GTEX-WFG7-0326-SM-3GILI GTEx Tissue Sample Gene Expression Profiles 1.0 1.00927 H9 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.37109 GSE164874_5_v_6_prednisolone_human RummaGEO Drug Perturbation Signatures 1.0 null intermediate filament COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.232029 cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.426265 CHD2 ENCODE Transcription Factor Targets 1.0 null cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.922286 FOXO1_KD_GDS2720_477_mouse_LSK GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H2AFZ_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H1693 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.12404 effect GeneRIF Biological Term Annotations 1.0 null GSE216043_3_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null hsa-miR-1271 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Anterior olfactory nucleus, external part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.60276 cerebellar cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.889193 USP14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45768 NALM1 CCLE Cell Line Gene Expression Profiles 1.0 1.52386 NCIH1836 CCLE Cell Line Gene Expression Profiles 1.0 1.92576 H3K4me3_B cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null Ciliated cell_Lung_Mouse CellMarker Gene-Cell Type Associations 1.0 null H3K4me3_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T6MN-2026-SM-4DM7L GTEx Tissue Sample Gene Expression Profiles 1.0 2.23431 Anteromedial visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5297 TIMM50 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05571 H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null phagocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.074135 GSE224096_2_v_0_cocaine_human RummaGEO Drug Perturbation Signatures -1.0 null Male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 mantle zone of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22883 Cell type cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.793 DARS Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-106b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 periventricular stratum of AStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00613 H3K27ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 NCIH2228 CCLE Cell Line Gene Mutation Profiles 1.0 null SP4 ENCODE Transcription Factor Targets 1.0 null cell COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 carbohydrate derivative binding GO Molecular Function Annotations 2015 1.0 null INT-747 DeepCoverMOA Drug Mechanisms of Action 1.0 0.42 purine nucleoside binding GO Molecular Function Annotations 2015 1.0 null H3K4me3_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HMY-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.53426 MAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.637 HNRNPUL1 Pathway Commons Protein-Protein Interactions 1.0 null GSE178532_1_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null superficial stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.98222 USF1_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPS5 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-QVJO-0006-SM-2S1RC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.35261 GTEX-S33H-0126-SM-4AD62 GTEx Tissue Sample Gene Expression Profiles 1.0 1.75442 GTEX-T8EM-0006-SM-3DB71 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.69555 neuroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067612 A549_Resveratrol_10nM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0152911 greek GeneRIF Biological Term Annotations 1.0 null LRIG1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76253 TE1 CCLE Cell Line Gene CNV Profiles -1.0 -2.08463 GSE133087_1_v_0_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE205070_2_v_9_mertk_mouse RummaGEO Gene Perturbation Signatures -1.0 null TBK1 Pathway Commons Protein-Protein Interactions 1.0 null r7 part of the nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27443 testis_4a HPA Tissue Sample Gene Expression Profiles 1.0 1.00131 EKVX cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.729 arcuate nucleus of hypothalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.54488 H3K4me3_epithelial cell of proximal tubule_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SURF4 Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-3944-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 Intestinal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.565 overnutrition GWASdb SNP-Disease Associations 1.0 0.75119 Sarcoma_SARC_TCGA-X2-A95T-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null TC-O 9311 DeepCoverMOA Drug Mechanisms of Action 1.0 0.33 Lymphoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.166 lateral ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.894777 snp GeneRIF Biological Term Annotations 1.0 null transferase activity, transferring phosphorus-containing groups GO Molecular Function Annotations 2015 1.0 null GSE261563_3_v_1_atrx_human RummaGEO Gene Perturbation Signatures 1.0 null PMC3253558__F1 PFOCR Pathway Figure Associations 2024 1.0 null PMC7064337-elife-51373-supp1.xlsx-MTF2_targets_shCTR-List_of_2011_genes_marked_by_MTF2_ChIPseq_in_control_conditions_shCTR_MTF2 Rummagene Transcription Factor Associations 2026 1.0 null GSE151612_4_v_2_pracinostat_human RummaGEO Drug Perturbation Signatures 1.0 null GSE216043_7_v_9_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-TKQ2-1526-SM-4DXUN GTEx Tissue Sample Gene Expression Profiles 1.0 1.74733 MKN7 CCLE Cell Line Gene CNV Profiles 1.0 2.20233 POLR2AphosphoS5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Thoracic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.395 retina TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.141609 H3K4me3_astrocyte of the cerebellum_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null U2904 DepMap CRISPR Gene Dependency 1.0 2.40728 SARS-CoV MA15_Day4-TNFRsf1b KO_None_GSE40824 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.97313 phosphorus metabolic process GO Biological Process Annotations 2015 1.0 null GTEX-OIZI-0126-SM-3NB13 GTEx Tissue Sample Gene Expression Profiles 1.0 1.33934 GTEX-XQ3S-0006-SM-4BOQ4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12011 GSE185163_5_v_2_clic4_mouse RummaGEO Gene Perturbation Signatures 1.0 null parabigeminal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06448 GTEX-OHPM-2626-SM-33HC5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0547 Sperm head-tail coupling apparatus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.612 GTEX-RWS6-0426-SM-47JXH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42956 FOXM1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hippocampus (hippocampal formation)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.22933 H3K4me3_epithelial cell of esophagus_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RERFLCAI CCLE Cell Line Gene CNV Profiles 1.0 1.35518 GSE207611,GSE207612_3_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null SIK2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OHPK-2426-SM-3MJGH GTEx Tissue Sample Gene Expression Profiles 1.0 0.841989 type iii intermediate filament COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.285876 C1orf109 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.20626 GABARAPL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22095 H2AFZ_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null metabolic process GO Biological Process Annotations 2015 1.0 null GSE175787_13_v_2_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null YY1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PSMA6 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_Skeletal Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZNF622_02_108 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59119 GTEX-S4P3-0926-SM-4AD54 GTEx Tissue Sample Gene Expression Profiles 1.0 0.960075 H3K27me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null WRNIP1 ENCODE Transcription Factor Targets 1.0 null PURG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17109 H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06315 alimentary canal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.059169 GTEX-WRHU-0926-SM-4E3IG GTEx Tissue Sample Gene Expression Profiles 1.0 1.04096 coronary artery disease GWASdb SNP-Disease Associations 1.0 0.705518 liver HPA Tissue Protein Expression Profiles -1.0 -0.896424 GTEX-Q2AI-0626-SM-48TZU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03804 TMEM147 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.28515 Prelimbic area, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69109 PCI-34051 DeepCoverMOA Drug Mechanisms of Action 1.0 1.14 H3K4me1_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-11A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2354 MAPK14 Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-19a TargetScan Predicted Conserved microRNA Targets 1.0 0.348832 Secretory granule lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.742 superficial stratum of r3Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12327 YBX1_01_257 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59206 H3K4me1_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-33-4533-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE158834_12_v_8_palmitic acid_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_cardiac fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null MAX_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Precommissural nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39711 amygdaloid complex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09423 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052524 Specific granule lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.308 PAX3_Knock-in_GDS3331_598_mouse_Palatal shelves (E14.5 embryos - palate) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MS751 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20336 dorsolateral prefrontal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.927348 APP Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VH-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE226249_2_v_3_pirfenidone_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null RPS3A Pathway Commons Protein-Protein Interactions 1.0 null thyroid gland HPA Tissue Gene Expression Profiles 1.0 0.936149 GTEX-WYJK-1626-SM-3NM9J GTEx Tissue Sample Gene Expression Profiles 1.0 0.881766 LB2518-MEL COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2A_HeLa-S3_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-WP-A9GB-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U4B1-1526-SM-4DXSL GTEx Tissue Sample Gene Expression Profiles 1.0 1.76363 H3K27me3_megakaryocyte_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Autonomic nervous system neoplasm DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.905 Brain Lower Grade Glioma_LGG_TCGA-VV-A86M-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE114284_4_v_3_irf1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WEY5-2326-SM-3GIKK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21794 Prelimbic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0826 SIN3A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HEY DepMap CRISPR Gene Dependency 1.0 5.18658 GAK Pathway Commons Protein-Protein Interactions 1.0 null GSE190316,GSE190324_1_v_9_rbm4_human RummaGEO Gene Perturbation Signatures 1.0 null PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-677-ENSG00000149050_ZNF214 Rummagene Transcription Factor Associations 2026 1.0 null FDFT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2566 GTEX-WYJK-0126-SM-3NMAB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.879121 hsa-miR-335 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null Agranular insular area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24391 H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SMAD4 ChEA Transcription Factor Targets 1.0 null GTEX-OOBJ-2026-SM-3NB1R GTEx Tissue Sample Gene Expression Profiles 1.0 0.839674 H3K4me3_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Carcinoma, Large Cell DisGeNET Gene-Disease Associations 1.0 null MYB-26560356-CHIP-SEQ-TH2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-WK11-0926-SM-3NMAU GTEx Tissue Sample Gene Expression Profiles 1.0 0.95023 PMC3875676__F4 PFOCR Pathway Figure Associations 2024 1.0 null PMC12496224-mmc5.xlsx-Correlation_between_GSC-Unnamed_1_GSC Rummagene Transcription Factor Associations 2026 1.0 null EMC-BAC-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-U412-0526-SM-3DB9I GTEx Tissue Sample Gene Expression Profiles -1.0 -0.852569 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040635 AR-19668381-PC3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.4224 H3K4me3_CD19 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE214382,GSE214383_1_v_2_ascl1_human RummaGEO Gene Perturbation Signatures 1.0 null UBB_KO_GDS3906_492_mouse_Testis - 14 Days GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Ectoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.633 GSE180641_0_v_1_zfp503_mouse RummaGEO Gene Perturbation Signatures 1.0 null posterior paraventricular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60587 GSE142210_9_v_7_panobinostat_human RummaGEO Drug Perturbation Signatures 1.0 null GSE95771_0_v_1_ruxolitinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null TAF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_HepG2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MAX_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QLQW-1026-SM-447A9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.87956 GTEX-PLZ4-1326-SM-2S1O7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.51214 Brain Lower Grade Glioma_LGG_TCGA-HT-A617-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_GM12864_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XLM4-3126-SM-4AT6M GTEx Tissue Sample Gene Expression Profiles 1.0 1.54694 POLR2AphosphoS5_U-87 MG_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE158197_5_v_4_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE167546_1_v_2_atrx_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K27me3_erythroblast_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE181517_0_v_1_doxorubicin_human RummaGEO Drug Perturbation Signatures -1.0 null MDA-MB-453 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.60779 GSE159937_1_v_0_tfcp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE133087_5_v_0_metformin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE226249_2_v_6_pirfenidone_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-WVLH-0626-SM-3MJG7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.04969 parathyroid gland HPA Tissue Protein Expression Profiles 1.0 0.857749 GTEX-PWN1-0126-SM-2I3FK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32883 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.46281 GSE112760,GSE112767_2_v_5_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE123861_1_v_0_sin3a_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_choroid plexus epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null NREP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.11925 H3K4me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70W-01A-12R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LS-411N COSMIC Cell Line Gene Mutation Profiles 1.0 null KARS Pathway Commons Protein-Protein Interactions 1.0 null posterior (caudal) superior temporal cortex (area 22c)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.980967 H3K4me3_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QESD-0006-SM-2I5G6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.994481 GTEX-WRHK-0005-SM-3MJF5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03234 caudal ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.18394 mitotic DNA damage checkpoint signaling GO Biological Process Annotations 2025 1.0 null primary auditory cortex (core)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.95452 GTF2F1 ENCODE Transcription Factor Targets 1.0 null primary motor cortex (area M1, area 4)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.83863 15902281-TableS1b GeneSigDB Published Gene Signatures 1.0 null CLOCK JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9264 reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.58494 GTEX-X4EP-0005-SM-3P5ZE GTEx Tissue Sample Gene Expression Profiles -1.0 -0.940233 GSE106661,GSE106665_2_v_3_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null periventricular nucleus, preoptic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.903017 GTEX-UJMC-0326-SM-3GAE2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07864 Uterine Carcinosarcoma_UCS_TCGA-N6-A4VC-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9me3_erythroblast_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null MAX_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null EB1 CCLE Cell Line Gene Expression Profiles 1.0 2.00089 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054953 Prostate cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.017 H3K4me1_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null macromolecule modification GO Biological Process Annotations 2015 1.0 null GTEX-R53T-0005-SM-3GADK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05995 Cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.905 ZNF75A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 61.7277 IZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.54574 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SF3B3 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-X8HC-0126-SM-4E3JW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.6375 H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q4-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-Y8-A894-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5461-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-N87 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.19098 PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Unnamed_1_FOXO1 Rummagene Transcription Factor Associations 2026 1.0 null Sarcoma_SARC_TCGA-HS-A5NA-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RUNX3 ENCODE Transcription Factor Targets 1.0 null H3K4me3_GM06990_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null SERBP1 Pathway Commons Protein-Protein Interactions 1.0 null UPF1 Pathway Commons Protein-Protein Interactions 1.0 null HLA-DOA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02341 H3K4me3_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GLI3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.1915 pattern GeneRIF Biological Term Annotations 1.0 null 9+2 motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.562 Stomach cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.059 H3K4me2_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC6683136-41598_2019_47363_MOESM4_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1_and_other_genes_ZEB1 Rummagene Transcription Factor Associations 2026 1.0 null Central nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.832 GTEX-WFG8-1926-SM-4LVM1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.54207 Obesity HuGE Navigator Gene-Phenotype Associations 1.0 null Lung adenocarcinoma_LUAD_TCGA-44-6147-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SNU81 CCLE Cell Line Gene Mutation Profiles 1.0 null caudal secondary prosencephalon Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05971 GSE202434,GSE202438_7_v_0_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null RAD21_MEL cell line_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE218060_7_v_6_decitabine_human RummaGEO Drug Perturbation Signatures -1.0 null PMC6344081-elife-40364-supp8.xlsx-PLZF-kd_2d_Diff_Vs_Ctrl_2d-diff-Symbol_ZBTB16 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-4524 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 male infertility MGI Mouse Phenotype Associations 2023 1.0 null Implantation fossa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.689 PMC8744729__F2 PFOCR Pathway Figure Associations 2024 1.0 null H3K9ac_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Posterolateral visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28775 fallopiantube_5a HPA Tissue Sample Gene Expression Profiles 1.0 0.829165 GTEX-SIU8-0626-SM-2XCDN GTEx Tissue Sample Gene Expression Profiles 1.0 1.29287 A549_Pracinostat_100nM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0140966 Liver hepatocellular carcinoma_LIHC_TCGA-DD-AA3A-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pyramidal layer of IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25707 PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-VJYA-0426-SM-3GIJK GTEx Tissue Sample Gene Expression Profiles 1.0 1.02462 MAZ_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SUM149PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.757422 Gastrointestinal system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.713 H3K4me3_HepG2_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.27395 nutrition disease GWASdb SNP-Disease Associations 1.0 0.484322 POLR2A_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null morphine_mus musculus_gpl6105_gds3703 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null PAPOLG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.91515 Cerebral cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.223 mononuclear cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.0721 Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OOBK-2126-SM-3LK5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.75708 GTEX-XBEC-0006-SM-4AT5T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.920553 GTEX-XLM4-0008-SM-4AT4W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.61523 RPS9 Pathway Commons Protein-Protein Interactions 1.0 null Adipose - Subcutaneous GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.65138 intermediate stratum of r10Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19453 H3K4me3_HCT116_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U3ZN-1426-SM-3DB87 GTEx Tissue Sample Gene Expression Profiles 1.0 0.969886 GTEX-QLQW-0005-SM-2S1RA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.938778 DST Pathway Commons Protein-Protein Interactions 1.0 null MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO ChEA Transcription Factor Targets 2022 1.0 null RPS10 Pathway Commons Protein-Protein Interactions 1.0 null SFRP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27425 GSE151612_4_v_7_pracinostat_human RummaGEO Drug Perturbation Signatures 1.0 null BX-912 LINCS KinomeScan Kinase Inhibitor Targets 1.0 1.30212 NCI-H1915 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.831554 patu8902 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.082 H3K4me3_fibroblast of upper leg skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null 496100448_TCx_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.96043 GTEX-X4EP-2926-SM-3P5YQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4452 Basolateral amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.00105 H3K9ac_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LA-01A-11R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KRT6B Pathway Commons Protein-Protein Interactions 1.0 null Tyrosinemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.493 placenta_6c HPA Tissue Sample Gene Expression Profiles -1.0 -1.23137 Hypertyrosinemia DisGeNET Gene-Disease Associations 1.0 null GTEX-V1D1-2126-SM-4JBH4 GTEx Tissue Sample Gene Expression Profiles 1.0 2.37075 infundibulum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.519253 resembles GeneRIF Biological Term Annotations 1.0 null NUMA1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-S4P3-0226-SM-3K2BD GTEx Tissue Sample Gene Expression Profiles 1.0 1.00571 Cortical amygdalar area, posterior part, medial zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72144 GSE81803,GSE81912_0_v_1_fmr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null layer III of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.16498 SW-48 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.702 GSE202434,GSE202438_3_v_5_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null Lassa Fever Virus_24hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.96004 A549_Abexinostat_10nM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0110425 colorectum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.232599 FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8025 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEF2C_MEF2C Rummagene Transcription Factor Associations 2026 1.0 null TPST2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.87235 EBF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.867 male infertility IMPC Knockout Mouse Phenotypes 1.0 null GSE207433_2_v_3_crtc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null SKM-1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.618 Paragigantocellular reticular nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0539 ASH-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null GSE235066_4_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null HS578T Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.79672 GTEX-XUJ4-1726-SM-4BONW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.10245 Agranular insular area, ventral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63281 GSE142684_2_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null independent GeneRIF Biological Term Annotations 1.0 null yap1_18413746_mcf10a_gof_human_gpl570_gds3220 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.453205 PACSIN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.85373 adipose tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.163365 GSK1059615 LINCS KinomeScan Kinase Inhibitor Targets 1.0 1.31878 Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE95771_0_v_2_ruxolitinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null H3K23me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null cochlear nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.05418 epithalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.503926 H3K4me3_keratinocyte_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-UTHO-3126-SM-3P5ZB GTEx Tissue Sample Gene Expression Profiles 1.0 1.30098 CDC42EP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14959 Spiral organ cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.073 MFE319 CCLE Cell Line Gene Mutation Profiles 1.0 null CUX1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S341-0326-SM-2XCAU GTEx Tissue Sample Gene Expression Profiles 1.0 1.35486 ZNF143_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NONO_02_65 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 2.87447 TBP ENCODE Transcription Factor Targets 1.0 null UBA52 Pathway Commons Protein-Protein Interactions 1.0 null arcuate nucleus of the hypothalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.878117 Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null intermediate stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6622 SNRPB2 Pathway Commons Protein-Protein Interactions 1.0 null GSE150215_1_v_0_etl4_mouse RummaGEO Gene Perturbation Signatures 1.0 null dorsolateral prefrontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.30336 GTEX-T2IS-2226-SM-4DM65 GTEx Tissue Sample Gene Expression Profiles 1.0 0.922649 Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XV7Q-2226-SM-4BRVY GTEx Tissue Sample Gene Expression Profiles 1.0 0.832234 FU97 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13253 GTEX-UJHI-1626-SM-3DB9A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00112 GTEX-UPJH-0926-SM-4IHKA GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0223 behavioral abnormality GWASdb SNP-Phenotype Associations 1.0 0.097849 lateral ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.49314 MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null mediodorsal nucleus of thalamus_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.1107 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GSE162892_3_v_0_isox_human RummaGEO Drug Perturbation Signatures 1.0 null AGRN Pathway Commons Protein-Protein Interactions 1.0 null primary auditory cortex (core)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.08152 CK2A1 Kinase Library Serine Threonine Kinome Atlas 1.0 null GTEX-XPVG-2226-SM-4B65U GTEx Tissue Sample Gene Expression Profiles 1.0 1.32484 GSE202434,GSE202438_7_v_5_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null KHDRBS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04598 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cortical subplate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.61244 PRKAA1 Pathway Commons Protein-Protein Interactions 1.0 null PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-w_SRPK2-KD-mouse_kinase_AR Rummagene Transcription Factor Associations 2026 1.0 null dorsofrontal pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09217 Hepatobiliary disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.218 Intake of total sugars GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.522185 H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null purine ribonucleotide binding GO Molecular Function Annotations 2015 1.0 null GSE114284_1_v_5_irf1_human RummaGEO Gene Perturbation Signatures -1.0 null skin_6a HPA Tissue Sample Gene Expression Profiles -1.0 -1.32689 HT-29 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.907248 smooth muscle HPA Tissue Protein Expression Profiles -1.0 -1.42179 FOXO1_KO_GSE46025_480_mouse_CD8 T cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null RPL4 Pathway Commons Protein-Protein Interactions 1.0 null H3K27me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null BHLHE40_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null superior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.05295 PANC1 CCLE Cell Line Gene CNV Profiles 1.0 1.93339 posterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.905994 POLR2AphosphoS5_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Fingolimod DeepCoverMOA Drug Mechanisms of Action -1.0 -0.47 Cortical amygdalar area, posterior part, lateral zone, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.02998 HCC2998 COSMIC Cell Line Gene Mutation Profiles 1.0 null Mesothelioma_MESO_TCGA-MQ-A4LJ-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE202434,GSE202438_4_v_0_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null hsa-miR-96 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 SPR Pathway Commons Protein-Protein Interactions 1.0 null nih 3T3 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.938022 cSARS Bat SRBD_72Hour_None_GSE37827 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.51634 Primary Malignant Neoplasm Of Lung DisGeNET Gene-Disease Associations 1.0 null cerebellar cortex_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.926836 EBF1 ENCODE Transcription Factor Targets 1.0 null intermediate stratum of PcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09217 GTEX-SE5C-0426-SM-4BRUI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11853 ALB Pathway Commons Protein-Protein Interactions 1.0 null GSE191105_2_v_3_nat1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Liver carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.25 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A3JJ-11A-12R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MYC ENCODE Transcription Factor Targets 1.0 null Gonad TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC8481886-Table_1.xlsx-A_subsets-iMSC_fetal_MSC_MSC Rummagene Transcription Factor Associations 2026 1.0 null CAMK2G Pathway Commons Protein-Protein Interactions 1.0 null SMC3 ENCODE Transcription Factor Targets 1.0 null GSE224096_1_v_0_cocaine_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me1_MEL cell line_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_epithelial cell of esophagus_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NALM19 CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-OXRN-2626-SM-48TBX GTEx Tissue Sample Gene Expression Profiles 1.0 1.44953 mediodorsal nucleus of thalamus_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.46198 RRBP1 Pathway Commons Protein-Protein Interactions 1.0 null CCT6A Pathway Commons Protein-Protein Interactions 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2978-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 H3K4me3_fibroblast of lung_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null USF1_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE102505_6_v_2_tunicamycin_human RummaGEO Drug Perturbation Signatures 1.0 null layer 3 of LPrP cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37629 H3K4me3_choroid plexus epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null YBX1 Pathway Commons Protein-Protein Interactions 1.0 null ventrolateral prefrontal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.8309 hsa-miR-548q TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 intermediate stratum of AStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09615 H3K4me1_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me2_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-SN8G-1526-SM-4DM79 GTEx Tissue Sample Gene Expression Profiles 1.0 0.835942 mitotic DNA integrity checkpoint signaling GO Biological Process Annotations 2023 1.0 null EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T6MO-0326-SM-32QOK GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 Squamous Cell Carcinoma DisGeNET Gene-Disease Associations 1.0 null Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hippocampus (hippocampal formation)_37 pcw_M_263195015 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.46407 ZBTB7A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.43974 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 BAG2 Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-W5WG-1426-SM-4KKZP GTEx Tissue Sample Gene Expression Profiles 1.0 0.881403 FLG2 Pathway Commons Protein-Protein Interactions 1.0 null USF2 ENCODE Transcription Factor Targets 1.0 null H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Peripheral nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.905 MYC-22102868-CA46-HUMAN-BLOOD-BURKITTSLYMPHOMA ChEA Transcription Factor Targets 2022 1.0 null TBX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.329 COLO679 CCLE Cell Line Gene Mutation Profiles 1.0 null coronary artery disease GWASdb SNP-Phenotype Associations 1.0 0.606562 GTEX-RVPV-0006-SM-2TF6Q GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 NCI-H2228 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null CTCF_GM12868_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPN2 Pathway Commons Protein-Protein Interactions 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2853-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SIU7-1126-SM-2XCDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.1717 EEA1 Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-7861-01A-11R-2232-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DDR1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-N7MS-0126-SM-3TW8O GTEx Tissue Sample Gene Expression Profiles 1.0 1.82199 RPL31 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_fibroblast of foreskin _hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-X8HC-0006-SM-46MV6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.962688 PMC10140619-mmc5.xlsx-Beta3_ConVsBSL-Gene_BHLHE22 Rummagene Transcription Factor Associations 2026 1.0 null GSE154936_3_v_2_remdesivir_human RummaGEO Drug Perturbation Signatures -1.0 null MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.30509 CAPAN-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.995 GSE174418,GSE174421_2_v_3_mettl5_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE140651,GSE140653_2_v_0_med1_human RummaGEO Gene Perturbation Signatures 1.0 null HNRNPUL2 Pathway Commons Protein-Protein Interactions 1.0 null disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.421016 CBX8_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ALYREF Pathway Commons Protein-Protein Interactions 1.0 null HCC2998 DepMap CRISPR Gene Dependency 1.0 5.6271 mitotic DNA damage checkpoint signaling GO Biological Process Annotations 2023 1.0 null POLR2A_HeLa-S3_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null amygdaloid complex_4 mos_M_12889 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.946738 GTEX-XAJ8-0826-SM-47JY6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.924012 placenta_6b HPA Tissue Sample Gene Expression Profiles -1.0 -0.87839 BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.01308 H3K4me1_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null POLR2AphosphoS5_U-87 MG_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null IFIT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13126 lateral habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.826771 HCC4017 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.53426 GTEX-P4PP-0126-SM-3LK69 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 intermediate stratum of the VAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.02998 GTEX-RU72-3126-SM-46MUB GTEx Tissue Sample Gene Expression Profiles 1.0 1.32749 POLR2AphosphoS2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Motile cilium COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.47 TANK Pathway Commons Protein-Protein Interactions 1.0 null GTEX-Q734-0526-SM-2I3EH GTEx Tissue Sample Gene Expression Profiles 1.0 0.843172 GSE186660_2_v_1_nicotine_mouse RummaGEO Drug Perturbation Signatures 1.0 null gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null A549_Dacinostat_100nM_72h Sci-Plex Drug Perturbation Signatures 1.0 0.00995091 HNRNPK Pathway Commons Protein-Protein Interactions 1.0 null AIMP2 Pathway Commons Protein-Protein Interactions 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6ME-01A-22R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE216043_10_v_8_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null intermediate stratum of p1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73981 GSE158834_10_v_8_palm_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-UJHI-1426-SM-3DB9C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3768 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.21396 POLR2A_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CBLL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.46892 GTEX-PVOW-0006-SM-3NMB8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01544 AP2A1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U412-0006-SM-3DB8J GTEx Tissue Sample Gene Expression Profiles -1.0 -1.14688 hsa-miR-520h TargetScan Predicted Conserved microRNA Targets 1.0 0.474009 POLR2AphosphoS5_HL-60_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-K1-A42X-02A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE205070_1_v_6_mertk_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE210885_2_v_1_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE57871_5_v_2_vorinostat_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_fibroblast of skin of abdomen_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null UACC893 DepMap CRISPR Gene Dependency 1.0 3.28516 Squamous Cell Carcinoma Of The Hypopharynx DisGeNET Gene-Disease Associations 1.0 null TDOTT DepMap CRISPR Gene Dependency 1.0 2.15497 inferior occipital gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.41052 H3K9ac_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE112761,GSE112767_1_v_3_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE205163,GSE205164_2_v_6_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null 496100341_TCx_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.02194 Noonan syndrome 6 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.1 Breast TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H3K4me2_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.40014 posteroventral (inferior) parietal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.4481 hsa-miR-1270 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 GTEX-V1D1-0926-SM-4JBHQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.17644 XMD16-144 LINCS KinomeScan Kinase Inhibitor Targets 1.0 0.880521 Perturb_6518_KD_S100A4_SRP105051 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 12.3122 HS 936.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.937833 Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE226439,GSE226441_6_v_2_hnf4g_human RummaGEO Gene Perturbation Signatures 1.0 null KRT16 Pathway Commons Protein-Protein Interactions 1.0 null NFE2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null nucleus of the inferior collicular brachium, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59976 STAT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22646 Lung small cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.001 Reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.214 GTEX-Q2AI-1226-SM-48U14 GTEx Tissue Sample Gene Expression Profiles 1.0 1.81926 GSE158834_11_v_8_palm_human RummaGEO Gene Perturbation Signatures -1.0 null Body mass index GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.6 Cnidoblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.737 DLST Pathway Commons Protein-Protein Interactions 1.0 null GSE193258,GSE193259_9_v_15_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE125014_1_v_2_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null MAX_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PSMD2 Pathway Commons Protein-Protein Interactions 1.0 null PNISR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27327 STAT3-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TCF4-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Outer dynein arm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.772 GSE217115_2_v_5_alectinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null EPPK1 Pathway Commons Protein-Protein Interactions 1.0 null GSE175787_4_v_10_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null GSE175683_3_v_2_angiotensin ii_mouse RummaGEO Drug Perturbation Signatures 1.0 null Chordoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.242 GSE210885_5_v_4_klf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null PTGER1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.42925 Prostate adenocarcinoma_PRAD_TCGA-G9-6365-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Internal female genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 HCT-8 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.711 PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-x_LPS-BMDCs-mouse_kinase_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null MXI1 ENCODE Transcription Factor Targets 1.0 null CTCF_CH12.LX_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null TBP_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null chr11_8491332_G_T_b38 GTEx eQTL 2025 1.0 1.78308 HCC70 CCLE Cell Line Gene CNV Profiles -1.0 -1.78966 IQGAP1 Pathway Commons Protein-Protein Interactions 1.0 null Retrosplenial area, lateral agranular part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01558 RPS11 Pathway Commons Protein-Protein Interactions 1.0 null GSE178714_5_v_2_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-15b TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 Pancreatic ductal adenocarcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.042 Hepatobiliary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.299 HNRNPH1 Pathway Commons Protein-Protein Interactions 1.0 null esophagus HPA Tissue Protein Expression Profiles 1.0 0.857749 lateral tuberal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16828 NCI-H1930 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06315 Pancreatic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.615 PFKP Pathway Commons Protein-Protein Interactions 1.0 null COLO 201 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17426 striatum_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08985 GTEX-R55C-0626-SM-2TF4Q GTEx Tissue Sample Gene Expression Profiles 1.0 0.975198 A549_CUDC-907_1µM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.00837161 QARS Pathway Commons Protein-Protein Interactions 1.0 null KRT77 Pathway Commons Protein-Protein Interactions 1.0 null NOP2 Pathway Commons Protein-Protein Interactions 1.0 null HS746T CCLE Cell Line Gene Mutation Profiles 1.0 null HRNR Pathway Commons Protein-Protein Interactions 1.0 null E2F6_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC5058748-oncotarget-07-31177-s002.xlsx-ZNF224_gene_peaks_promoter-Table_S3_Genes_that_contain_a_ZNF224_enriched_region_within_1_kb_of_the_transcription_ZNF224 Rummagene Transcription Factor Associations 2026 1.0 null superficial stratum of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28228 19808870-ST1 GeneSigDB Published Gene Signatures 1.0 null PAX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S9-ZNF384_SpecDMCs-Unnamed_3_ZNF384 Rummagene Transcription Factor Associations 2026 1.0 null ventral pallium Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25319 DYNLL1 Pathway Commons Protein-Protein Interactions 1.0 null purine ribonucleoside triphosphate binding GO Molecular Function Annotations 2015 1.0 null MELK Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_fibroblast of pulmonary artery_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null r1 part of vestibulocerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02015 H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE77108_4_v_7_saha_human RummaGEO Drug Perturbation Signatures -1.0 null GLMN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.613 H3K4me3_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null EB2 CCLE Cell Line Gene Expression Profiles 1.0 2.79065 EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Anteromedial visual area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04169 GTEX-XV7Q-0326-SM-4BRVM GTEx Tissue Sample Gene Expression Profiles 1.0 0.859771 layer 2 of InsCx Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56301 GTEX-S3XE-1526-SM-4AD5A GTEx Tissue Sample Gene Expression Profiles 1.0 1.58721 HCC38 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.40386 H3K9ac_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-PWO3-0011-R8A-SM-2I5GD GTEx Tissue Sample Gene Expression Profiles 1.0 1.00695 RPL23 Pathway Commons Protein-Protein Interactions 1.0 null hippocampus (hippocampal formation)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.903654 MXI1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null thyroid GTEx Tissue Gene Expression Profiles 1.0 0.84743 GTEX-XV7Q-1526-SM-4BRWB GTEx Tissue Sample Gene Expression Profiles 1.0 1.011 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.027143 Testis GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.64765 MARK2 Pathway Commons Protein-Protein Interactions 1.0 null Penis_Foreskin_Melanocyte_Primary_Cells_skin03 Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.870512 KLF5-20875108-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE88819_7_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null YY1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RFX5_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BHLHE40 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.0942 SRP14 Pathway Commons Protein-Protein Interactions 1.0 null GSE235701,GSE261434_2_v_3_enasidenib_human RummaGEO Drug Perturbation Signatures -1.0 null BNC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4106 GNL3 Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-20a TargetScan Predicted Conserved microRNA Targets 1.0 0.474009 hsa-miR-519c-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.37496 RPL14 Pathway Commons Protein-Protein Interactions 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MA-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prelimbic area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46856 SIN3A_Panc1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100367_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.4889 ZNF714 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04318 H3K4me3_kidney_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE205163,GSE205164_2_v_4_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null CEBPB_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-424 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 Sarcoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.091 abnormal emotion/affect behavior GWASdb SNP-Phenotype Associations 1.0 0.280529 POLR2A_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CCDC177 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1093 endocrine gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.158951 liver HPA Tissue Gene Expression Profiles -1.0 -1.29479 NAP1L1 Pathway Commons Protein-Protein Interactions 1.0 null PSKH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08466 H3K27me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mitotic DNA integrity checkpoint signaling GO Biological Process Annotations 2025 1.0 null KELLY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.60654 hsa-miR-2278 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 MDAMB453 CCLE Cell Line Gene CNV Profiles -1.0 -1.80532 POLR2A_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brachial Amyotrophic Diplegia DisGeNET Gene-Disease Associations 1.0 null TP53BP1 Pathway Commons Protein-Protein Interactions 1.0 null amygdalo-striatal transition Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00849 GSE88819_3_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null vagina HPA Tissue Protein Expression Profiles 1.0 0.857749 Uterine cervix TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 KRT13 Pathway Commons Protein-Protein Interactions 1.0 null NFIC_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null large intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.25259 GSE158834_12_v_4_palm_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-PX3G-0126-SM-2I3EN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03122 dermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.151114 MCF7 CCLE Cell Line Gene CNV Profiles -1.0 -1.56598 intracellular membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null Colon cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.299 PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Gene_Name_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE88819_5_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null SW 620 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.12907 catalytic activity GO Molecular Function Annotations 2015 1.0 null RPLP0 Pathway Commons Protein-Protein Interactions 1.0 null posteromedial cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.80018 USF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of villous mesenchyme_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XLM4-1526-SM-4AT6D GTEx Tissue Sample Gene Expression Profiles 1.0 1.91174 Protein kinase domain InterPro Predicted Protein Domain Annotations 1.0 null H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE175787_5_v_2_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null GSE163240_3_v_0_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null RPS7 Pathway Commons Protein-Protein Interactions 1.0 null Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_CH12.LX_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null MAX_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null AAK1 Pathway Commons Protein-Protein Interactions 1.0 null PSMA2 Pathway Commons Protein-Protein Interactions 1.0 null dorsal juxtacommissural pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41393 Brain Lower Grade Glioma_LGG_TCGA-WY-A85B-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HSPA5 Pathway Commons Protein-Protein Interactions 1.0 null ATF3 ENCODE Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DB-A64O-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NPM1 Pathway Commons Protein-Protein Interactions 1.0 null GSE158834_10_v_3_palmitic acid_human RummaGEO Drug Perturbation Signatures -1.0 null PMC11133462-41467_2024_47218_MOESM5_ESM.xlsx-IL-10_SBNO2_KD-symbol_AR Rummagene Transcription Factor Associations 2026 1.0 null urogenital system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 RPSA Pathway Commons Protein-Protein Interactions 1.0 null GSE165334_2_v_0_dabrafenib_human RummaGEO Drug Perturbation Signatures 1.0 null LOUCY CCLE Cell Line Gene Expression Profiles 1.0 1.49012 E2F1-17053090-MCF7-human ChEA Transcription Factor Binding Site Profiles 1.0 null arcuate nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.42589 H3K4me1_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HNRNPM Pathway Commons Protein-Protein Interactions 1.0 null disease of metabolism GWASdb SNP-Disease Associations 1.0 0.176394 Perturb_16508_OE_Rest_SRP314492 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 7.76476 macrophage TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.086081 Synaptic vesicle, readily releasable pool COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.634 NCM-460 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.988 GTEX-X4XY-0826-SM-4E3JM GTEx Tissue Sample Gene Expression Profiles 1.0 0.898509 GSE202434,GSE202438_8_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE226770_1_v_6_atrx_human RummaGEO Gene Perturbation Signatures 1.0 null TRIM28_02_63 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.04439 GSE226249_0_v_3_pirfenidone_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-QCQG-1426-SM-48U22 GTEx Tissue Sample Gene Expression Profiles 1.0 0.876323 ILF3 Pathway Commons Protein-Protein Interactions 1.0 null GSE195514_0_v_1_stk25_human RummaGEO Gene Perturbation Signatures -1.0 null KDM1A_KD_GDS5055_367_mouse_adipose tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null periventricular stratum of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17731 H2AFZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H2AFZ_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null kras GeneRIF Biological Term Annotations 1.0 null GSE168458_1_v_3_disulfiram_mouse RummaGEO Drug Perturbation Signatures -1.0 null COLO 320DM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.875866 hsa-miR-10b-5p MiRTarBase microRNA Targets 1.0 null H3K4me1_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null IDS Pathway Commons Protein-Protein Interactions 1.0 null GTEX-T5JC-2526-SM-4DM6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.11379 RPL27 Pathway Commons Protein-Protein Interactions 1.0 null EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-LT-A5Z6-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Foreskin fibroblast cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.546 GSE138863_3_v_0_disulfiram_human RummaGEO Drug Perturbation Signatures 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null endocrine gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 KYSE-30 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04769 MAX JASPAR Predicted Transcription Factor Targets 1.0 null GSE189789_0_v_1_oridonin_human RummaGEO Drug Perturbation Signatures 1.0 null Psoriasis vulgaris_Skin tissue_GSE14905 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -2.89694 dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.865072 A549_BMS-754807_10µM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0101294 H3K4me1_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null diencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.091985 Brain ventricle TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WL46-3026-SM-3LK7Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.57974 hsa-miR-3607-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 Brain Lower Grade Glioma_LGG_TCGA-DU-7012-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE169356_0_v_5_ivermectin_human RummaGEO Drug Perturbation Signatures 1.0 null TRIM28 Pathway Commons Protein-Protein Interactions 1.0 null medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.80309 GSE86507,GSE86509_4_v_8_hoxb7_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE210682_0_v_3_methadone_human RummaGEO Drug Perturbation Signatures -1.0 null Melanoma DisGeNET Gene-Disease Associations 1.0 null hypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.182133 GSE161170,GSE161268_1_v_3_med1_human RummaGEO Gene Perturbation Signatures 1.0 null HSP90AA1 Pathway Commons Protein-Protein Interactions 1.0 null RPS14 Pathway Commons Protein-Protein Interactions 1.0 null Subpallium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.548 ependymal epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.627081 hsa-miR-520b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.47676 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null tanycyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.12217 GSE228106_3_v_2_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null PMC13187244-41392_2026_2766_MOESM2_ESM.xlsx-Table_S17-Table_S17_Differentially_expressed_genes_in_OCI-AML3_cells_ZMIZ1_inhibitor_SIH-001_4E_vs_DMSO_RUNX2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-VJYA-0005-SM-3P5ZD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3415 SU-DHL-6 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.89474 LNCAPCLONEFGC CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-XGQ4-2026-SM-4AT6G GTEx Tissue Sample Gene Expression Profiles 1.0 1.82639 ls123 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.555 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null DSC1 Pathway Commons Protein-Protein Interactions 1.0 null Kidney cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.1 Sarcoma_SARC_TCGA-DX-AB2J-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC7526497-JEM_20191688_TableS2.xlsx-Supplemental_Table_2-Supplemental_Table_2_List_of_ZBTB24-regulated_genes_identified_by_RNA-seq_ZBTB24 Rummagene Transcription Factor Associations 2026 1.0 null MYC_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSK3B Pathway Commons Protein-Protein Interactions 1.0 null H3K27me3_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-497 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.94743 H3K4me1_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MAX ENCODE Transcription Factor Targets 1.0 null THOC2 Pathway Commons Protein-Protein Interactions 1.0 null SLC45A4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02934 GSE173262_6_v_0_ash1l_mouse RummaGEO Gene Perturbation Signatures -1.0 null Microtubule cytoskeleton COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 GSE131377_1_v_0_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-XMD1-0011-R8A-SM-4AT48 GTEx Tissue Sample Gene Expression Profiles 1.0 0.946647 organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Sarcoma_SARC_TCGA-DX-A6B9-01A-12R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCOR1 ENCODE Transcription Factor Targets 1.0 null GTEX-P4PP-2426-SM-3P61L GTEx Tissue Sample Gene Expression Profiles 1.0 0.883074 GSE145323,GSE145324_1_v_2_rfx3_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me1_G1E-ER4_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null PMC9203705-10.1182-2021014723_bloodbld2021014723-suppl2.xlsx-Supp_Table_5-Supplementary_Table_5_List_of_genes_identified_by_WGCNA_corresponding_to_the_CDX2_UBTF_cluster_CDX2 Rummagene Transcription Factor Associations 2026 1.0 null Reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.295 Serine/threonine-protein kinase, active site InterPro Predicted Protein Domain Annotations 1.0 null retina BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.844473 Endocrine gland cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.681 H3K4me3_LNCaP clone FGC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC3012117-pone.0015793.s008.xls-Sheet1-Table_S3_The_list_of_TFE3_regulated_genes_with_MiTF_TFE_binding_sequence_in_their_promoters_TFE3 Rummagene Transcription Factor Associations 2026 1.0 null GSE158834_2_v_4_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null external globus pallidum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01142 PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR Rummagene Transcription Factor Associations 2026 1.0 null mantle zone of LAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.07624 H3K4me1_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Parataenial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08415 OB olfactory fiber layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09615 GSE239844_8_v_9_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null caudal prosubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08316 hsa-miR-526b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 hsa-miR-20a TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 PLEC Pathway Commons Protein-Protein Interactions 1.0 null CP in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17515 SP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.53353 PMC5503627-oncotarget-08-39497-s003.xlsx-hyper_in_shUHRF1_KD-Unnamed_7_AR Rummagene Transcription Factor Associations 2026 1.0 null CAR-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.81891 HL-7702 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.916 periventricular stratum of PcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.05402 GTEX-PX3G-2626-SM-2I3EG GTEx Tissue Sample Gene Expression Profiles 1.0 0.880438 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4834-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TAF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEP170B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.73275 PMC12629863-CAC2-45-1547-s002.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Kinases_predicted_to_phosphorylat_YY1_at_Ser247_YY1 Rummagene Transcription Factor Associations 2026 1.0 null MAP3K11 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null STAT1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PRELID3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.62854 nutrition disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.256228 ELF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WHSE-3126-SM-3P5ZI GTEx Tissue Sample Gene Expression Profiles 1.0 1.01795 YWHAG Pathway Commons Protein-Protein Interactions 1.0 null central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.4892 20860821-TableS5 GeneSigDB Published Gene Signatures 1.0 null Calcium/calmodulin-dependent/calcium-dependent protein kinase InterPro Predicted Protein Domain Annotations 1.0 null PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null Colonic epithelium cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.654 GSE154074_1_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null FAM83H Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GO-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null disease of mental health GWASdb SNP-Disease Associations 1.0 0.09461 Rectum adenocarcinoma_READ_TCGA-AH-6549-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BT483 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.06387 PANC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.81891 H4K91ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-RWS6-2026-SM-2XCB5 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 primary auditory cortex (core)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.924313 H3K4me1_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-R55E-2726-SM-48FCX GTEx Tissue Sample Gene Expression Profiles 1.0 1.83414 Urinary system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.006 Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-SUCS-0006-SM-4DM59 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2092 hsa-miR-4757-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 PMC3355086-pgen.1002728.s003.xlsx-Tabelle1-HEY2_downregulated_HEY2 Rummagene Transcription Factor Associations 2026 1.0 null SOX10 MotifMap Predicted Transcription Factor Targets 1.0 null chr11_8462542_C_T_b38 GTEx eQTL 2025 1.0 1.60306 triangular septal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00446 chr11_8483981_A_T_b38 GTEx eQTL 2025 1.0 2.92257 H3K9ac_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me1_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73558 GSE152432_5_v_2_zrsr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null CD177 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.97324 GSE144231_3_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE131649_6_v_5_hemin_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_fibroblast of upper leg skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null bone marrow HPA Tissue Protein Expression Profiles -1.0 -2.3529 medial ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.05746 Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null colorectal cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.458759 PMC9530161-41419_2022_5296_MOESM2_ESM.xlsx-Tab6_KDM5C-KD-up_genes-Table_6_Up_regulated_genes_in_KDM5C-KD_KDM5C-KD1_Control_overlap_KDM5C-KD2_Control_AR Rummagene Transcription Factor Associations 2026 1.0 null POLR2AphosphoS5_HL-60_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null FB-66-UU47_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.205488 GSE112762,GSE112767_1_v_3_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null hematopoietic cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05183 posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.37261 Piriform-amygdalar area, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.82839 JUN ENCODE Transcription Factor Targets 1.0 null MAX_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mental depression GWASdb SNP-Disease Associations 1.0 0.618776 POLR2A_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZEB1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-138 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 nucleotide binding GO Molecular Function Annotations 2015 1.0 null HNRNPA1 Pathway Commons Protein-Protein Interactions 1.0 null H3K27ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_B cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MXI1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X5EB-2026-SM-4E3KA GTEx Tissue Sample Gene Expression Profiles 1.0 1.90298 GSE131161_3_v_4_rarres1_mouse RummaGEO Gene Perturbation Signatures -1.0 null fat_8b HPA Tissue Sample Gene Expression Profiles -1.0 -0.914651 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JA-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE162892_3_v_0_sox9_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-SNOS-0006-SM-32PLH GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02695 Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041188 RPL13 Pathway Commons Protein-Protein Interactions 1.0 null Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.067 H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.80123 GTEX-NPJ7-2926-SM-3MJGQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.57109 496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.07303 E2F1 ChEA Transcription Factor Targets 1.0 null cellular protein metabolic process GO Biological Process Annotations 2015 1.0 null FBXW5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15058 H3K4me3_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XQ3S-2726-SM-4BOP2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.68868 H3K4me1_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_CD14-positive monocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE165636_0_v_4_tofacitinib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE116354,GSE117379_3_v_5_cox2_mouse RummaGEO Gene Perturbation Signatures -1.0 null RARG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26767 A-875 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.877 lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16493 PKM Pathway Commons Protein-Protein Interactions 1.0 null Nervous system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.905 ATP5F1A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19098 H3K4me3_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZNF331 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.1795 nicotine dependence GWASdb SNP-Disease Associations 1.0 1.24687 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5454-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUND ENCODE Transcription Factor Targets 1.0 null TNIK Pathway Commons Protein-Protein Interactions 1.0 null GSE175787_13_v_0_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null GSE210580_0_v_7_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC4060771-170289.f1.pdf-393-DMRT2_DMRT2 Rummagene Transcription Factor Associations 2026 1.0 null GSE158834_7_v_6_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GSE240896,GSE240899_2_v_4_ccnt1_human RummaGEO Gene Perturbation Signatures -1.0 null superficial stratum of isLim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22542 Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QH-01A-11R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Body mass index GWAS Catalog SNP-Phenotype Associations 1.0 0.483518 H3K27me3_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPL7A Pathway Commons Protein-Protein Interactions 1.0 null transferase activity GO Molecular Function Annotations 2015 1.0 null EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H3K9ac_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QDVJ-1726-SM-2I5FX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.31211 GTEX-XPVG-0006-SM-4B65Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.978184 SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null CHD2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE202434,GSE202438_4_v_5_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-ENSG_ID_RFX2 Rummagene Transcription Factor Associations 2026 1.0 null hMPV_12Hour_18234263_GSE8961 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.61731 GTEX-S7SE-0726-SM-2XCD7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.862498 H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null liver_d HPA Tissue Sample Gene Expression Profiles -1.0 -2.07549 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null E2F6 ENCODE Transcription Factor Targets 1.0 null GSE125219,GSE125221_3_v_8_arid1a_human RummaGEO Gene Perturbation Signatures 1.0 null GSDMD CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.49448 liver GTEx Tissue Gene Expression Profiles -1.0 -1.49475 H3K4me1_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null testis_7f HPA Tissue Sample Gene Expression Profiles 1.0 1.05853 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null GSE144231_6_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Nucleus sagulum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.54865 SNCA_KO_GDS4153_527_mouse_striatum GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null chr11_8528336_T_C_b38 GTEx eQTL 2025 1.0 1.23777 Darunavir DeepCoverMOA Drug Mechanisms of Action 1.0 0.29 GTEX-SE5C-0726-SM-4BRWY GTEx Tissue Sample Gene Expression Profiles 1.0 0.907918 PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE158834_7_v_5_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.42744 GSE235066_4_v_5_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null organelle LOCATE Predicted Protein Localization Annotations 1.0 null superficial stratum of LAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53926 12471243-TableS2 GeneSigDB Published Gene Signatures 1.0 null GTEX-X4XX-0008-SM-46MVK GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0433 GTEX-P78B-1926-SM-3P616 GTEx Tissue Sample Gene Expression Profiles 1.0 1.10303 GTEX-XBEC-0126-SM-4GIDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.65135 Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null plexiform layer of TuStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05242 PMC10140619-mmc5.xlsx-Rank_Beta1-Beta3-Gene_BHLHE22 Rummagene Transcription Factor Associations 2026 1.0 null GSE200673,GSE200691_2_v_5_hmga2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.815 Large intestine cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.635 Dorsomedial nucleus of the hypothalamus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11076 H3K4me3_HeLa-S3_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null BRCA1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_10_CCF-Affected_Genes_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-S4Z8-0526-SM-4AD4T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.891796 CTCF_GM12864_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Autonomic nervous system neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.069 H3K4me3_foreskin fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null TP63 ChEA Transcription Factor Targets 1.0 null ZFYVE16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14724 Malignant exocrine pancreas neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.216 GTEX-U8XE-1026-SM-4E3HM GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 hsa-miR-646 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 HCT-15 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.105 H3K4me3_cardiac mesoderm_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null KELLY CCLE Cell Line Gene CNV Profiles -1.0 -1.42294 anterior hypothalamic area, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.857388 Lung adenocarcinoma_LUAD_TCGA-62-A470-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE169356_2_v_1_ivermectin_human RummaGEO Drug Perturbation Signatures -1.0 null children GeneRIF Biological Term Annotations 1.0 null viscus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053729 SUZ12_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null TCF3 ENCODE Transcription Factor Targets 1.0 null E2F1-17053090-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K9ac_Brain Inferior Temporal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-U8T8-0005-SM-3DB8F GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 cellular protein modification process GO Biological Process Annotations 2015 1.0 null GTEX-X261-3226-SM-3NMC3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.33956 H3K27me3_G1E_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF ENCODE Transcription Factor Targets 1.0 null BLOC1S3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.2305 GTEX-X5EB-0726-SM-46MVR GTEx Tissue Sample Gene Expression Profiles 1.0 0.938662 Paraventricular nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.07551 Loperamide (hydrochloride)_HEC-1-A Tahoe Therapeutics Tahoe 100M Perturbation Atlas -1.0 -0.00791318 oculomotor nuclear complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.880591 POU2F2_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WL46-0126-SM-3TW8I GTEx Tissue Sample Gene Expression Profiles 1.0 0.941829 Perturb_1187_KD_BCL6_SRP187038 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -7.77944 H3K4me3_fibroblast of pulmonary artery_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Sperm flagellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.391 PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null Basomedial amygdalar nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.82839 intracellular non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04644 GTEX-PSDG-0005-SM-3GADC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29914 chr11_8514375_G_A_b38 GTEx eQTL 2025 1.0 2.08412 GTEX-WH7G-1926-SM-4LVMM GTEx Tissue Sample Gene Expression Profiles 1.0 1.86726 striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.849707 GTEX-SUCS-0226-SM-32PLQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.974189 SNUC5 CCLE Cell Line Gene CNV Profiles -1.0 -2.59447 GTEX-U3ZH-1526-SM-4DXV1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.52511 PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaDadj_vs_NC-Gene_ERG Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_kidney epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HDAC2 ENCODE Transcription Factor Targets 1.0 null GTEX-QDVJ-0226-SM-2I5FV GTEx Tissue Sample Gene Expression Profiles 1.0 1.01487 small intestine HPA Tissue Protein Expression Profiles 1.0 0.857749 PRPF6 Pathway Commons Protein-Protein Interactions 1.0 null cellular macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XMD3-2326-SM-4AT5H GTEx Tissue Sample Gene Expression Profiles 1.0 0.860964 RANGAP1 Pathway Commons Protein-Protein Interactions 1.0 null H3K23ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-T5JW-0326-SM-4DM6J GTEx Tissue Sample Gene Expression Profiles 1.0 0.945085 Head and neck cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.006 EPRS Pathway Commons Protein-Protein Interactions 1.0 null NRF1_02_62 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.41504 H3K27me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Phosphatidylinositol 3-kinase complex, class I COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.705 SNU668 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-3926-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE210885_2_v_4_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-PLZ4-1226-SM-2I5FE GTEx Tissue Sample Gene Expression Profiles 1.0 0.829741 DMS454 CCLE Cell Line Gene CNV Profiles 1.0 1.56367 arterial stenosis GWASdb SNP-Phenotype Associations 1.0 0.234657 DTWD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.2037 GTEX-S341-0226-SM-2XCAX GTEx Tissue Sample Gene Expression Profiles 1.0 0.916571 ventrolateral prefrontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.846931 estradiol_homo sapiens_gpl570_gds3283 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE142210_3_v_10_panobinostat_human RummaGEO Drug Perturbation Signatures 1.0 null H3K79me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SMC3_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Melanoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.047 NCIH1105 CCLE Cell Line Gene Expression Profiles 1.0 2.85538 H3K27me3_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ebolavirus(EBOV)_7day_Splenocytes_19683682_GSE17509 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.90841 preoptic region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.939307 KYSE-510 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29337 GTEX-UJMC-2026-SM-3GADR GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 GTEX-QXCU-0326-SM-2TC63 GTEx Tissue Sample Gene Expression Profiles 1.0 0.85523 alimentary canal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Pancreatic cancer cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.371 GSE85880,GSE85881_0_v_2_tretinoin_human RummaGEO Drug Perturbation Signatures 1.0 null GSE192870_2_v_0_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null intracellular part LOCATE Predicted Protein Localization Annotations 1.0 null Cortical amygdalar area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70205 RT-112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.60794 GTEX-PVOW-2726-SM-48TCA GTEx Tissue Sample Gene Expression Profiles 1.0 1.91393 Sarcoma_SARC_TCGA-PT-A8TR-01A-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner CP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.34644 HNRNPC Pathway Commons Protein-Protein Interactions 1.0 null TMEM30A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05472 GSE235066_4_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null TGF-beta_OE_GDS2974_137_mouse_corneas GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE202434,GSE202438_13_v_5_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null HCC1500 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.18909 ZNF384 ENCODE Transcription Factor Targets 1.0 null GSE221577_2_v_0_pik3r1_human RummaGEO Gene Perturbation Signatures -1.0 null lateral terminal nucleus of the accessory optic tract, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72944 Axonemal central pair COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.153 H3K4me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC3253558__F1 PFOCR Pathway Figure Associations 2023 1.0 null PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_1_AR Rummagene Transcription Factor Associations 2026 1.0 null H2AFZ_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ESRRB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.9886 CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.69733 Multiple myeloma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.116 GTEX-R3RS-0726-SM-3GIJR GTEx Tissue Sample Gene Expression Profiles 1.0 1.31039 uterus TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null COPB1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TRC complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.46 GM12878 Roadmap Epigenomics Cell and Tissue Gene Expression Profiles 1.0 0.880803 MARK1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null lung TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054414 EEF1AKMT4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00509 MAX_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UJHI-1926-SM-3DB8Z GTEx Tissue Sample Gene Expression Profiles -1.0 -0.995096 Perturb_10359_KD_Ascl1_SRP340223 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 496100453_HIP_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.0579 r3 part of spinal trigeminal sensory column, oral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12327 PMC5577301-in-17-237-s001.xls-AR_downregulated_DEGs-Kidney_GSE9493_GENE_AR Rummagene Transcription Factor Associations 2026 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NN-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dependent GeneRIF Biological Term Annotations 1.0 null POLR2A_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHAGOK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.58486 EOMES ChEA Transcription Factor Targets 1.0 null FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-XXEK-1126-SM-4BRUX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2535 GTEX-XUYS-0126-SM-47JWZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.912008 Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_embryonic fibroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4671-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.348832 Outer dense fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.746 H3K4me3_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KM-8439-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.606 RXRA::VDR JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1 GTEX-X4EP-0126-SM-3P5YV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.49161 NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.899122 RPS8 Pathway Commons Protein-Protein Interactions 1.0 null ELK1 ENCODE Transcription Factor Targets 1.0 null hsa-miR-16-5p MiRTarBase microRNA Targets 1.0 null hsa-miR-301a TargetScan Predicted Conserved microRNA Targets 1.0 0.997906 PRKAB1 Pathway Commons Protein-Protein Interactions 1.0 null PMC8528285-pbio.3001085.s010.xlsx-Fig_7A-MLX_TESTES_MLX Rummagene Transcription Factor Associations 2026 1.0 null A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_3Hour_None_GSE43203 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.55217 GSE110248_1_v_6_romidepsin_human RummaGEO Drug Perturbation Signatures 1.0 null NCI-H2122 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.655 lower dorsal lateral hypothalamic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19221 GSE239844_6_v_10_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null induseum griseum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25808 GTEX-WZTO-3026-SM-3NMA2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.78922 GTEX-OXRP-0006-SM-2I3FN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18856 GSE146865,GSE146866_4_v_3_saracatinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-QDVN-2326-SM-2S1PF GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-PAX6-M_PAX6 Rummagene Transcription Factor Associations 2026 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null TNK2 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of mammary gland_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SPTAN1 Pathway Commons Protein-Protein Interactions 1.0 null RPL12 Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-663 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 GTEX-WFJO-1026-SM-3GIKL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.927044 LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47269 H3K4me3_fibroblast of lung_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null intermediate periretromammillary nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12578 H3K4me3_WI38_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC12640707-NIHMS2124006-supplement-Supplemental_tables.xlsx-Supplemental_Table_S5-Supplemental_Table_S5_Genes_commonly_downregulated_in_both_clones_of_ZFX-depleted_HEK293T_cells_in_Ni_et_al_2020_ZFX Rummagene Transcription Factor Associations 2026 1.0 null Cortical amygdalar area, posterior part, lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72144 GSE154074_2_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Tumor Angiogenesis DisGeNET Gene-Phenotype Associations 1.0 null GTEX-U3ZM-1626-SM-4DXSK GTEx Tissue Sample Gene Expression Profiles 1.0 1.68594 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 MAZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80V-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Median eminence TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.151 PABPC1 Pathway Commons Protein-Protein Interactions 1.0 null ZKSCAN1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PEO4 DepMap CRISPR Gene Dependency 1.0 2.96336 A549_Tacedinaline_10µM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0166422 intercalated amygdaloid nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6491 KDM5A ENCODE Transcription Factor Targets 1.0 null GTEX-NPJ8-1426-SM-3MJHR GTEx Tissue Sample Gene Expression Profiles 1.0 1.3374 MTA3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K36me3_testis_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null molecular_function GO Molecular Function Annotations 2015 1.0 null chr11_8594392_G_A_b38 GTEx eQTL 2025 1.0 5.51269 microcellular tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.40755 leukocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052884 Small cell lung cancer cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.841 GTEX-WOFL-0006-SM-3TW8K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04665 B-cell lymphoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.006 Dorsal nucleus raphe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08845 PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null intracellular membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GTEX-U8T8-1126-SM-4DXUE GTEx Tissue Sample Gene Expression Profiles 1.0 1.5841 pituitary GTEx Tissue Gene Expression Profiles 1.0 1.6551 posteroventral (inferior) parietal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.35382 E2F4-21247883-LYMPHOBLASTOID-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null bronchoalveolar system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067051 PRKAB2 Pathway Commons Protein-Protein Interactions 1.0 null H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2790-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE202434,GSE202438_2_v_5_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null Carcinogenesis DisGeNET Gene-Phenotype Associations 1.0 null SUZ12 ChEA Transcription Factor Targets 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20Q-11A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.7076 GTEX-OXRK-0626-SM-2HMJ5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.829657 HUG1N CCLE Cell Line Gene CNV Profiles -1.0 -2.3514 GTEX-XK95-0226-SM-4AT58 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.924642 pineal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.553683 GSE218060_2_v_4_decitabine_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE210662_2_v_1_znf165_human RummaGEO Gene Perturbation Signatures -1.0 null RPL23A Pathway Commons Protein-Protein Interactions 1.0 null primary auditory cortex (core)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -3.05343 CAMKK2 Pathway Commons Protein-Protein Interactions 1.0 null Pancreas disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.567 RFX5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T8EM-0126-SM-4DM5R GTEx Tissue Sample Gene Expression Profiles 1.0 2.06569 chr11_8504440_T_C_b38 GTEx eQTL 2025 1.0 1.32801 H3K4me3_HL-60_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GLB1L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.60485 GSE178714_6_v_2_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null artery disease GWASdb SNP-Disease Associations 1.0 0.112345 RPS15A Pathway Commons Protein-Protein Interactions 1.0 null DNM1L CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23898 disease of metabolism DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.58494 H3K4me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Piriform area, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41077 H3K4me1_megakaryocyte_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null PSMD12 Pathway Commons Protein-Protein Interactions 1.0 null lung epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.401765 NFE2 ENCODE Transcription Factor Targets 1.0 null XRCC6 Pathway Commons Protein-Protein Interactions 1.0 null Cervical carcinoma cell TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 496100607_TCx_dementia_TBI_77_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.16531 Gustatory areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41732 Hematopoietic system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.279 POLR2A_bone marrow_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ESRRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.574 dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.37563 MEL270 DepMap CRISPR Gene Dependency 1.0 5.27954 Nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.37 H3K27me3_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null testis TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Flagellate TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.063 abnormality of the cardiovascular system GWASdb SNP-Phenotype Associations 1.0 0.046449 superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18728 disease of cellular proliferation GWASdb SNP-Disease Associations 1.0 0.051096 CTCF_MEL cell line_mm9_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null EP300_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BAG5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.35528 H3K27me3_G1E-ER4_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPL10 Pathway Commons Protein-Protein Interactions 1.0 null posteroventral (inferior) parietal cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.861784 posterior (caudal) superior temporal cortex (area 22c)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.90287 PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaDadj_vs_NC-Gene_ERG Rummagene Transcription Factor Associations 2026 1.0 null Nervous system disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.905 Prostate adenocarcinoma_PRAD_TCGA-EJ-7797-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HNF4, COUP MotifMap Predicted Transcription Factor Targets 1.0 null H3K27me3_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POU2F2 ENCODE Transcription Factor Targets 1.0 null HCC515 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.192 ULK3 Pathway Commons Protein-Protein Interactions 1.0 null HMEpC cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.015 GSE158834_12_v_4_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null GSE48812_11_v_6_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_Breast vHMEC Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCIH2342 CCLE Cell Line Gene Expression Profiles -1.0 -2.08285 NKX2-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4843 GTEX-U3ZG-0006-SM-47JWX GTEx Tissue Sample Gene Expression Profiles -1.0 -0.827759 H3K4me3_BJ_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CAT Pathway Commons Protein-Protein Interactions 1.0 null lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.46458 posteroventral (inferior) parietal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.50848 EXOSC10 Pathway Commons Protein-Protein Interactions 1.0 null AHNAK Pathway Commons Protein-Protein Interactions 1.0 null CSE1L Pathway Commons Protein-Protein Interactions 1.0 null GSE226249_5_v_3_pirfenidone_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me3_WI38_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TKQ2-0006-SM-33HBH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.826478 H3K4me1_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of the aortic adventitia_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary auditory cortex (core)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01429 all GWASdb SNP-Phenotype Associations 1.0 0.04125 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell part GO Cellular Component Annotations 2015 1.0 null ZNF157 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.0 Hypopharynx TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.944 GTEX-O5YT-2126-SM-3MJGD GTEx Tissue Sample Gene Expression Profiles 1.0 1.45787 Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A656-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.229919 TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T5JW-1226-SM-3GACY GTEx Tissue Sample Gene Expression Profiles 1.0 0.992161 A549_Entinostat_10µM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0142745 H3K4me3_A549_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XUJ4-1326-SM-4BOQ9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.884524 DLD-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.830353 H3K4me3_fibroblast of mammary gland_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null SUZ12 ENCODE Transcription Factor Targets 1.0 null abnormality of the vasculature GWASdb SNP-Phenotype Associations 1.0 0.093561 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05599 primary motor-sensory cortex (samples)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.29155 Brain Lower Grade Glioma_LGG_TCGA-HT-8011-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_5255_KO_Morc3_SRP318570 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 9.81029 PPP1CA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.6351 VHL_Deficiency_GDS3769_513_mouse_Immortalized embryonic fibroblasts GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE175787_13_v_10_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null primary auditory cortex (core)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.25995 skin_5e HPA Tissue Sample Gene Expression Profiles -1.0 -1.04751 H4K8ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null manchette assembly GO Biological Process Annotations 2025 1.0 null bmi GeneRIF Biological Term Annotations 1.0 null H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SNU1040 CCLE Cell Line Gene Mutation Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XYKS-1426-SM-4BRUO GTEx Tissue Sample Gene Expression Profiles -1.0 -1.32306 olfactory bulb Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22533 Serine/threonine/dual specificity protein kinase, catalytic domain InterPro Predicted Protein Domain Annotations 1.0 null SFPQ Pathway Commons Protein-Protein Interactions 1.0 null NCIH1963 CCLE Cell Line Gene Expression Profiles 1.0 1.49263 increased fasting circulating glucose level MGI Mouse Phenotype Associations 2023 1.0 null H3K4me3_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25Y-01A-11R-A16W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH292 CCLE Cell Line Gene CNV Profiles 1.0 1.38766 CBP-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE131161_5_v_4_rarres1_mouse RummaGEO Gene Perturbation Signatures -1.0 null STAT3 ChEA Transcription Factor Targets 1.0 null paralemniscal isthmic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39193 dorsolateral prefrontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.826101 RESF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.59696 H2AFZ_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE158834_7_v_4_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null Ebl TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.536 PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null Neuroblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.069 HESPERADIN DGIdb Drug Targets 2026 1.0 0.66165 H3K4me1_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A5TW-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1703 CCLE Cell Line Gene CNV Profiles -1.0 -1.96313 H3K79me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Protein kinase, ATP binding site InterPro Predicted Protein Domain Annotations 1.0 null intermediate stratum of DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30629 caudal division of IPC (area 39) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.36078 H3K4me3_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Calu-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.192 RUNX3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null YWHAZ Pathway Commons Protein-Protein Interactions 1.0 null RPS23 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me2_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HSD17B4 Pathway Commons Protein-Protein Interactions 1.0 null horizontal nucleus of the diagonal band Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02781 GSE154074_1_v_4_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE158834_7_v_3_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null COMPOUND 1 [PMID: 21742770] DGIdb Drug Targets 2026 1.0 13.233 GSE123943_4_v_0_sox1_human RummaGEO Gene Perturbation Signatures 1.0 null RPL19 Pathway Commons Protein-Protein Interactions 1.0 null eye TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.084564 lung cancer GWASdb SNP-Disease Associations 1.0 1.24687 SNRNP40 Pathway Commons Protein-Protein Interactions 1.0 null NCIH2286 CCLE Cell Line Gene Mutation Profiles 1.0 null GSE158431_2_v_3_pioglitazone_mouse RummaGEO Drug Perturbation Signatures 1.0 null cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.948581 H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null membrane-bounded organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 OCILY3 CCLE Cell Line Gene Expression Profiles 1.0 1.77205 EIF3B Pathway Commons Protein-Protein Interactions 1.0 null GTL-16 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.937833 Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bcl11b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.4501 mRNA_ZSCAN4C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null NOMO-1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.569 Stomach GTEx Tissue Gene Expression Profiles 2023 -1.0 -0.650137 Secondary Malignant Neoplasm Of Lymph Node DisGeNET Gene-Disease Associations 1.0 null EP300_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H2135 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null inner CP in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.972845 KRT1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null CX-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.907248 GTEX-R55D-0126-SM-48FEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.54127 HCC1569 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.937833 H3K4me3_fibroblast of pedal digit skin_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null BCAP31 Pathway Commons Protein-Protein Interactions 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OS-01A-12R-A220-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE206870,GSE206872_1_v_2_ascl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null abnormalities of the peripheral arteries GWASdb SNP-Phenotype Associations 1.0 0.234657 SMC2 Pathway Commons Protein-Protein Interactions 1.0 null KMS11 CCLE Cell Line Gene Expression Profiles 1.0 1.63941 POLR2A_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH1435 CCLE Cell Line Gene Mutation Profiles 1.0 null ZNF214 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.8006 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null STK10 Pathway Commons Protein-Protein Interactions 1.0 null superficial stratum of InsCx (cortical plate/marginal zone) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04762 Sarcoma_SARC_TCGA-3B-A9HR-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DCD Pathway Commons Protein-Protein Interactions 1.0 null GSE158431_5_v_1_pioglitazone_mouse RummaGEO Drug Perturbation Signatures -1.0 null cerebellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.160838 OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.45377 AURKB Pathway Commons Protein-Protein Interactions 1.0 null NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.02433 GSE172016_2_v_0_paclitaxel_human RummaGEO Drug Perturbation Signatures 1.0 null hsa-miR-4456 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 GSE221004_3_v_2_prdm6_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XOT4-0005-SM-4B64S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07415 Lung adenocarcinoma_LUAD_TCGA-78-7167-01A-11R-2066-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE114284_4_v_0_irf1_human RummaGEO Gene Perturbation Signatures -1.0 null HNRNPF Pathway Commons Protein-Protein Interactions 1.0 null ACTL6A Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3363-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_ES-Bruce4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null internal cortical nucleus of inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17119 H3K27me3_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Non-Small Cell Lung Carcinoma DisGeNET Gene-Disease Associations 1.0 null CHD7 ENCODE Transcription Factor Targets 1.0 null cellular_component COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 PARD6B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32397 Cortical amygdalar area, posterior part, medial zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42343 GTEX-S32W-1326-SM-4AD5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.75832 WIDR Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.908463 GSE172146_2_v_0_mettl1_human RummaGEO Gene Perturbation Signatures 1.0 null intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CUL4A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22664 CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null internal female genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QXCU-0006-SM-2TC5K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.38594 GTEX-RU72-0006-SM-2TF65 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 POLR2A_GM18505_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RBMX Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M5-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TMZS-0006-SM-3DB8G GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 MAX_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-8158-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null basomedial amygdaloid nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74191 Basolateral amygdalar nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.71148 SCH DepMap CRISPR Gene Dependency 1.0 3.25541 PRDX1 Pathway Commons Protein-Protein Interactions 1.0 null hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.04254 GTEX-XBEW-0226-SM-4AT6A GTEx Tissue Sample Gene Expression Profiles 1.0 1.70587 periventricular stratum of r1BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08629 respiratory system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053998 fallopiantube_8e HPA Tissue Sample Gene Expression Profiles 1.0 0.935885 PRKAG1 Pathway Commons Protein-Protein Interactions 1.0 null PNMA2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01079 NEXN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14381 GTEX-WFON-1926-SM-3LK7L GTEx Tissue Sample Gene Expression Profiles -1.0 -0.852633 CREB3L4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4077 H3K9me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2871-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12186250-NIHMS2085662-supplement-3.xlsx-4111_TEAD4_peaks-Nearest_Ensembl_TEAD4 Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Body mass index (joint analysis main effects and physical activity interaction) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.809691 H3K4me2_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null FA-63-WI26_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.229234 H4K20me1_K562_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XPT6-1626-SM-4B655 GTEx Tissue Sample Gene Expression Profiles 1.0 1.32465 TAF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-R55F-0005-SM-2TF4W GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 GSE175787_11_v_9_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null KRT17 Pathway Commons Protein-Protein Interactions 1.0 null GSE210885_3_v_1_klf4_mouse RummaGEO Gene Perturbation Signatures 1.0 null laterostriatal stripe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00153 cuneiform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25129 testis_7d HPA Tissue Sample Gene Expression Profiles 1.0 1.35632 Irf1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.1021 periventricular stratum of r8BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29976 ALDH3A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12117 GSE102505_6_v_0_tunicamycin_human RummaGEO Drug Perturbation Signatures 1.0 null GlobusPallidus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.963854 Lassa Fever Virus_4hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.08458 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q8-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5L3-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HEC251 CCLE Cell Line Gene Mutation Profiles 1.0 null H3K4me3_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null intermediate stratum of PHyB-P Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12547 CSNK2A1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-TML8-1926-SM-32QOS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.872344 primary motor cortex (area M1, area 4)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.14041 GTEX-UJHI-1526-SM-3DB99 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 ATF3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Peripheral nervous system neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.064 H3K4me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null KRT10 Pathway Commons Protein-Protein Interactions 1.0 null PRKCA Pathway Commons Protein-Protein Interactions 1.0 null H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pallium Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37015 PSMC3 Pathway Commons Protein-Protein Interactions 1.0 null GSE216043_7_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-UJHI-0006-SM-3DB8H GTEx Tissue Sample Gene Expression Profiles -1.0 -0.829373 GSE225869_2_v_0_cd44_human RummaGEO Gene Perturbation Signatures 1.0 null Inflammation CTD Gene-Disease Associations 1.0 1.32786 orbital frontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.23487 Perturb_2264_Mut_H33A_SRP223446 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 PMC2883591-pgen.1000979.s003.xls-NRSF_GENELISTS_WitOut_GeneSig_g-Supplemental_Table_3_REST Rummagene Transcription Factor Associations 2026 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Y-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Dentate gyrus, granule cell layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02262 H3K4me3_Breast Myoepithelial Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null mononuclear phagocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.081843 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QG-01A-12R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AR ChEA Transcription Factor Targets 1.0 null SW 900 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10516 SMARCA4 Pathway Commons Protein-Protein Interactions 1.0 null GSE121043_0_v_1_aldh1a1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE96777,GSE96778_3_v_2_zbtb4_human RummaGEO Gene Perturbation Signatures -1.0 null posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.137 POLR2AphosphoS5_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC38 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.05916 PANC0203 CCLE Cell Line Gene CNV Profiles 1.0 2.09825 H3K9ac_fibroblast of lung_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PAX5 ENCODE Transcription Factor Targets 1.0 null 19334046-TableS3b GeneSigDB Published Gene Signatures 1.0 null H4K5ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Disease of anatomical entity DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.905 496100415_PCx_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.0872 hsa-miR-944 TargetScan Predicted Conserved microRNA Targets 1.0 0.257113 intestine TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.070542 dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.994351 H3K4me3_Stomach Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null cervical carcinoma cell TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null subbrachial nucleus, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 4.01021 primary motor cortex (area M1, area 4)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.917318 OVKATE CCLE Cell Line Gene CNV Profiles -1.0 -1.36691 GTEX-XUZC-0005-SM-4BOQ8 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.88315 GTEX-T5JW-1626-SM-3GADZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05489 PMC4944136-srep28995-s2.xls-OTX2-gene_OTX2 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null X Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04906 intracellular organelle COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.907248 SF268 CCLE Cell Line Gene CNV Profiles 1.0 1.75837 GTEX-WFJO-0005-SM-3GIKY GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D5-01A-11R-A31O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CHD1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H292 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47269 r10 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19421 mRNA_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null MR49F cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.651 ZNF326 Pathway Commons Protein-Protein Interactions 1.0 null Adrenocortical carcinoma_ACC_TCGA-OR-A5JT-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cortical amygdalar area, posterior part, medial zone, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.85954 Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11578 EIF3A Pathway Commons Protein-Protein Interactions 1.0 null A549_Mocetinostat_1µM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0109547 group GeneRIF Biological Term Annotations 1.0 null GTEX-T2IS-0626-SM-32QP6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.1495 H3K4me1_CH12.LX_mm9_4 ENCODE Histone Modification Site Profiles 1.0 null HNRNPAB Pathway Commons Protein-Protein Interactions 1.0 null mediodorsal nucleus of thalamus_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.24944 PMC6879454-Data_Sheet_1.xlsx-AA_in_vitro-Unnamed_4_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null H3K27ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Liver cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.285 Trunk TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GTEX-XAJ8-1426-SM-47JYM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.884582 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7XP-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-UPIC-0005-SM-3GACV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.09948 RFX5 ENCODE Transcription Factor Targets 1.0 null GTEX-SSA3-0005-SM-32QOT GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 membrane-bounded organelle LOCATE Predicted Protein Localization Annotations 1.0 null DDX5 Pathway Commons Protein-Protein Interactions 1.0 null SKMEL28 CCLE Cell Line Gene CNV Profiles 1.0 1.35182 184A1N4 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.02075 H2AFZ_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.33109 KRT2 Pathway Commons Protein-Protein Interactions 1.0 null A549_Pracinostat_1µM_72h Sci-Plex Drug Perturbation Signatures 1.0 0.0180143 hsa-miR-935 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 GSE158834_2_v_4_palm_human RummaGEO Gene Perturbation Signatures 1.0 null TCF4 ChEA Transcription Factor Targets 1.0 null Hand1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 30.3399 GSE214823,GSE214824_0_v_1_crtc2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A8XE-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U8T8-2226-SM-3DB95 GTEx Tissue Sample Gene Expression Profiles 1.0 1.16846 TP53 JASPAR Predicted Transcription Factor Targets 1.0 null intermediate stratum of PHyB-I Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18764 Prostate adenocarcinoma_PRAD_TCGA-G9-6348-11A-01R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hematopoietic stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06683 Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H1 Cells Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 2.18293 ribavirin_homo sapiens_gpl570_gds4391 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6V9-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.181 hsa-miR-106a TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 KTN1 Pathway Commons Protein-Protein Interactions 1.0 null Acute myeloid leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.205 GTEX-QV31-0726-SM-3GAEG GTEx Tissue Sample Gene Expression Profiles 1.0 1.05511 GSE131161_1_v_4_rarres1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Piriform-amygdalar area, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.28356 496100287_TCx_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.2392 NCIH2029 CCLE Cell Line Gene Expression Profiles 1.0 2.26603 GTEX-P78B-0005-SM-2I5GM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.956436 POLR2A_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2564 TEAD4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ion binding GO Molecular Function Annotations 2015 1.0 null GSE112761,GSE112767_1_v_0_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.676528 IARS Pathway Commons Protein-Protein Interactions 1.0 null USF1_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X4EP-3226-SM-3P5YR GTEx Tissue Sample Gene Expression Profiles 1.0 0.948445 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QEG5-0226-SM-2I5GI GTEx Tissue Sample Gene Expression Profiles -1.0 -0.861501 H3K4me3_fibroblast of pedal digit skin_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lymphatic system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.173 CTCF_MEL cell line_mm9_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4633-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 VZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.884906 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 GTEX-SNMC-1026-SM-4DM7K GTEx Tissue Sample Gene Expression Profiles 1.0 1.72473 DMS153 CCLE Cell Line Gene Mutation Profiles 1.0 null PMC3029394-pone.0016617.s001.xls-Up-regulated-Table_S1_Genes_up-regulated_by_SOX2_over-expression_2_0-fold_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null dorsolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.13208 TEAD4_02_40 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.75489 XMD11-50 LINCS KinomeScan Kinase Inhibitor Targets 1.0 0.850157 GSE193258,GSE193259_9_v_12_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null Ewings Sarcoma-Primitive Neuroectodermal Tumor (Pnet) DisGeNET Gene-Disease Associations 1.0 null cerebralcortex BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.896365 CP in rostral hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14415 ATP5A1 Pathway Commons Protein-Protein Interactions 1.0 null pc3 HPA Cell Line Gene Expression Profiles -1.0 -0.969415 GSE161170,GSE161268_0_v_2_med1_human RummaGEO Gene Perturbation Signatures -1.0 null depression GWASdb SNP-Phenotype Associations 1.0 0.52536 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17289 AKT1_Activation - 2 week induction_GDS2308_717_mouse_Heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null asthenozoospermia MGI Mouse Phenotype Associations 2023 1.0 null Flagellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.102 PMC8437976-41416_2021_1470_MOESM2_ESM.xls-List_of_MAF_in_SNP_Rectum-Hugo_Symbol_MAF Rummagene Transcription Factor Associations 2026 1.0 null Nucleus prepositus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16374 HA1E TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.139 RCOR1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Intestinal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.633 H3K4me3_fibroblast of skin of abdomen_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null outer plexiform layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.723631 thrombocytopenia MGI Mouse Phenotype Associations 2023 1.0 null Axonemal central apparatus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.139 skin_5f HPA Tissue Sample Gene Expression Profiles -1.0 -0.868416 GSE240030,GSE252532_0_v_2_atrx_human RummaGEO Gene Perturbation Signatures -1.0 null EIF3F Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DH-A7UV-01A-12R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EW22 DepMap CRISPR Gene Dependency 1.0 4.3343 primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.917702 H3K27me3_cardiac mesoderm_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null cytoskeletal part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04971 GTEX-N7MT-1026-SM-3TW8T GTEx Tissue Sample Gene Expression Profiles 1.0 1.4033 GTEX-P4QS-2626-SM-2I3EV GTEx Tissue Sample Gene Expression Profiles 1.0 0.995634 H3K27ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Retrosplenial area, lateral agranular part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17616 PSMD3 Pathway Commons Protein-Protein Interactions 1.0 null FOXD4L4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34029 GTEX-RWSA-0826-SM-2XCBF GTEx Tissue Sample Gene Expression Profiles 1.0 1.13475 DYNC1LI2 Pathway Commons Protein-Protein Interactions 1.0 null HSPA8 Pathway Commons Protein-Protein Interactions 1.0 null GSE163240_2_v_0_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null PLK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.40652 GSE229468,GSE229471_0_v_3_znf587_human RummaGEO Gene Perturbation Signatures -1.0 null Ciliated epithelial cell_Esophagus_Human CellMarker Gene-Cell Type Associations 1.0 null dorsal tuberomammillary nucleus, intermediate part (histaminergic) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79185 Myeloid neoplasm DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.058 CMLT1 CCLE Cell Line Gene Expression Profiles 1.0 2.17471 ARG1 Pathway Commons Protein-Protein Interactions 1.0 null HSPA1B Pathway Commons Protein-Protein Interactions 1.0 null GTEX-XAJ8-1026-SM-47JY9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02156 GTEX-RM2N-0526-SM-2TF4N GTEx Tissue Sample Gene Expression Profiles 1.0 1.01356 HCC1806 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33846 Serous cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.741 PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_CoCl2-HIF2_-related_miRNA_targets_expression_during_hypoxia_based_on_micorarray_FC_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null EZH2 ENCODE Transcription Factor Targets 1.0 null biological_process GO Biological Process Annotations 2015 1.0 null H3K27ac_fibroblast of lung_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K9ac_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCIH1355 CCLE Cell Line Gene CNV Profiles -1.0 -2.00354 GTEX-XBEC-1526-SM-4AT68 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.829991 gonad TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 H3K4me1_G1E-ER4_mm9_3 ENCODE Histone Modification Site Profiles 1.0 null dorsal thalamus_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.35182 thrombocytopenia IMPC Knockout Mouse Phenotypes 1.0 null GSE193258,GSE193259_2_v_12_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null E2F4 ChEA Transcription Factor Targets 1.0 null LARS Pathway Commons Protein-Protein Interactions 1.0 null NCI-H650 COSMIC Cell Line Gene Mutation Profiles 1.0 null chr11_8610943_C_A_b38 GTEx eQTL 2025 1.0 4.09902 H3K9ac_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_epithelial cell of proximal tubule_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null stk33 GeneRIF Biological Term Annotations 1.0 null PHF8 ENCODE Transcription Factor Targets 1.0 null GTEX-OXRO-0006-SM-2I5EM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19332 hindbrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.162748 Basolateral amygdalar nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52774 marrow cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.069853 GEMIN5 Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.17289 hacat HPA Cell Line Gene Expression Profiles -1.0 -0.969415 A-375SM cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.76 primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.15065 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7242-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ventropallial amygdalopiriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51365 PMC10291819-13287_2023_3380_MOESM11_ESM.pdf-50-HOXC11_HOXC11 Rummagene Transcription Factor Associations 2026 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STK3 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-X5EB-0426-SM-46MVY GTEx Tissue Sample Gene Expression Profiles 1.0 1.13629 H3K4me1_mononuclear cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC9894241-pnas.2211429119.sd05.xlsx-G4_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null LNCaP-95 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.702 GTEX-WXYG-2326-SM-4E3I6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.11652 H3K4me3_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-66-2754-01A-01R-0980-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-OXRN-0126-SM-48TDM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12444 A549_Alisertib_10µM_72h Sci-Plex Drug Perturbation Signatures 1.0 0.0150502 GSE94814_1_v_0_reck_mouse RummaGEO Gene Perturbation Signatures -1.0 null Tanycyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.387 intermediate isthmic part of the dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18376 related GeneRIF Biological Term Annotations 1.0 null GTEX-NPJ8-1326-SM-3LK6B GTEx Tissue Sample Gene Expression Profiles -1.0 -0.857385 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary motor-sensory cortex (samples)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.07765 VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29933 Kidney renal clear cell carcinoma_KIRC_TCGA-B2-4098-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-8500-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_3245_OE_RUNX3_SRP330291 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 1.96156 Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ACTN4 Pathway Commons Protein-Protein Interactions 1.0 null GSE146612_1_v_3_amiodarone_human RummaGEO Drug Perturbation Signatures -1.0 null Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pancreatic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.240497 PMC8528285-pbio.3001085.s010.xlsx-Fig_7E-MLX_TESTES_MLX Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE135030_8_v_2_fludarabine_human RummaGEO Drug Perturbation Signatures 1.0 null TNPO1 Pathway Commons Protein-Protein Interactions 1.0 null PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null Tiplaxtinin DeepCoverMOA Drug Mechanisms of Action -1.0 -0.27 LIM1215 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.637 GTEX-U3ZN-0626-SM-3DB7U GTEx Tissue Sample Gene Expression Profiles 1.0 0.858356 hsa-miR-302e TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 NCI-H1355 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.87719 GSE196104,GSE196106_2_v_1_vsx2_mouse RummaGEO Gene Perturbation Signatures -1.0 null DDX21 Pathway Commons Protein-Protein Interactions 1.0 null cerebellar cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06324 EP300 ENCODE Transcription Factor Targets 1.0 null GSE242199_6_v_0_ntrk2_human RummaGEO Gene Perturbation Signatures 1.0 null MAZ ENCODE Transcription Factor Targets 1.0 null GSE191021_1_v_0_nono_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_Caco-2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SLC36A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52012 GTEX-U8XE-1926-SM-3DB98 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 High grade glioma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.153 SP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12576 POLR2A_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-S4Q7-1226-SM-4AD5I GTEx Tissue Sample Gene Expression Profiles 1.0 1.5457 Body Mass Index Procedure DisGeNET Gene-Phenotype Associations 1.0 null GTEX-R55C-1426-SM-48FED GTEx Tissue Sample Gene Expression Profiles 1.0 1.5829 PMC4221415__F5 PFOCR Pathway Figure Associations 2024 1.0 null GSE140651,GSE140653_5_v_7_med1_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_Panc1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-U3ZN-0326-SM-3DB86 GTEx Tissue Sample Gene Expression Profiles 1.0 1.06335 external part of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6661 RPS20 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-S33H-0005-SM-2XCAL GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Radial spoke COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.031 NANOG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14741 Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10W-01A-11R-A131-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null USF2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Perturb_4874_KO_SUZ12_SRP095403 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 Infralimbic area, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05003 GTEX-WH7G-2026-SM-3NMBL GTEx Tissue Sample Gene Expression Profiles -1.0 -0.891904 GTEX-QVUS-0011-R1A-SM-3GAD2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.15052 ZIM3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.9679 H3K4me3_megakaryocyte_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null TAF1 ENCODE Transcription Factor Targets 1.0 null GTEX-X3Y1-0626-SM-3P5YS GTEx Tissue Sample Gene Expression Profiles 1.0 0.950247 GTEX-RVPV-1226-SM-2TF73 GTEx Tissue Sample Gene Expression Profiles 1.0 1.11012 BMP2K Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-301b TargetScan Predicted Conserved microRNA Targets 1.0 0.997906 protein kinase activity GO Molecular Function Annotations 2015 1.0 null subcuneiform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.34465 GSE193258,GSE193259_9_v_13_osimertinib_human RummaGEO Drug Perturbation Signatures 1.0 null PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null APOB Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_Adult Liver Roadmap Epigenomics Histone Modification Site Profiles 1.0 null abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.057033 IER3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31648 Perturb_10356_KD_BRD4_SRP093774 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 lymph node HPA Tissue Protein Expression Profiles 1.0 0.857749 intermediate filament cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.232029 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M6-01A-11R-A13Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXD4L1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41619 GTEX-S95S-1126-SM-4B64E GTEx Tissue Sample Gene Expression Profiles 1.0 1.58695 MLXIPL JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.9475 GTEX-VJYA-1426-SM-4KL1Y GTEx Tissue Sample Gene Expression Profiles 1.0 1.408 GSE189609_1_v_0_hax1_human RummaGEO Gene Perturbation Signatures 1.0 null RANBP2 Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-3394-11A-01R-1758-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_bone marrow macrophage_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null outer CP in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.879065 GTEX-OHPN-0005-SM-2YUML GTEx Tissue Sample Gene Expression Profiles -1.0 -0.93209 SIN3A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null IGROV1 CCLE Cell Line Gene Mutation Profiles 1.0 null RPL10A Pathway Commons Protein-Protein Interactions 1.0 null GSE226397_0_v_1_cystine_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE158458_2_v_3_sorafenib_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-XMK1-2026-SM-4B65K GTEx Tissue Sample Gene Expression Profiles 1.0 1.57483 GSE230573_1_v_0_dcaf1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WYBS-1926-SM-3NM8N GTEx Tissue Sample Gene Expression Profiles 1.0 1.01802 HNRNPD Pathway Commons Protein-Protein Interactions 1.0 null OCT4-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null peduncular part of dorsomedial hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.84877 PRMT1 Pathway Commons Protein-Protein Interactions 1.0 null SW-480 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.359 NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.06697 H3K9ac_Pancreatic Islets Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3443-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SNRNP200 Pathway Commons Protein-Protein Interactions 1.0 null nucleus GO Cellular Component Annotations 2025 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-6984-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE48812_4_v_6_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null u937 HPA Cell Line Gene Expression Profiles -1.0 -0.969415 Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NFYB_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNRNPR Pathway Commons Protein-Protein Interactions 1.0 null Lung adenocarcinoma_LUAD_TCGA-91-6847-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE235066_4_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null IC-05-AW29_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.223577 superficial stratum of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72991 Male reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.127 cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 USF1_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null caudal ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.63505 GOLGB1 Pathway Commons Protein-Protein Interactions 1.0 null cellular_component GO Cellular Component Annotations 2015 1.0 null CA2 field, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.960962 Ciliary plasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.351 Oral mucosa TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 TMEFF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.45827 BxPC-3 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.859 Lung adenocarcinoma_LUAD_TCGA-53-7813-01A-11R-2170-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-4594-01A-01R-1201-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Intercalated amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53926 GSE108675_3_v_0_slc1a4_mouse RummaGEO Gene Perturbation Signatures 1.0 null Female reproductive system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.007 lateral subdivision of area 9 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.41745 Ciliated cell_Trachea_Mouse CellMarker Gene-Cell Type Associations 1.0 null superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.86817 HERC2 Pathway Commons Protein-Protein Interactions 1.0 null PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-Upstream_NAME_MSC Rummagene Transcription Factor Associations 2026 1.0 null GTEX-U8XE-1526-SM-4E3HT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4285 Colonic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.341 POLR2A_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-106a TargetScan Predicted Conserved microRNA Targets 1.0 0.454769 subcutis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.43146 GTEX-RN64-2326-SM-48FDW GTEx Tissue Sample Gene Expression Profiles 1.0 1.47048 embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.054488 HCC1806 CCLE Cell Line Gene CNV Profiles 1.0 2.11256 acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.272343 H3K4me1_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HCC2814 CCLE Cell Line Gene CNV Profiles 1.0 1.49588 H3K9ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-QEG4-0006-SM-2I5FY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25861 Cortical amygdalar area, posterior part, medial zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.77764 GTEX-PWOO-0926-SM-2I3EC GTEx Tissue Sample Gene Expression Profiles 1.0 0.9193 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7058-01A-11R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_BJ_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null KRT73 Pathway Commons Protein-Protein Interactions 1.0 null H3K27ac_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE207514,GSE207515_0_v_3_acetylcysteine_human RummaGEO Drug Perturbation Signatures -1.0 null striatum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.826547 hippocampus BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.21705 superficial stratum of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22883 hsa-miR-1908 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 lateral spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15205 H3K4me1_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cellular metabolic process GO Biological Process Annotations 2015 1.0 null Immune system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.105 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q5-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KMS-26 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.20392 RPL17 Pathway Commons Protein-Protein Interactions 1.0 null Kidney Chromophobe_KICH_TCGA-KM-8441-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056631 PMC8528285-pbio.3001085.s010.xlsx-Fig_S7A-GENE_LIST_UPLOADED_TO_ENRICHR_MLX_TESTES_855_GENES_MLX Rummagene Transcription Factor Associations 2026 1.0 null GSE206870,GSE206872_0_v_2_ascl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-106b TargetScan Predicted Conserved microRNA Targets 1.0 0.474009 gastrointestinal tract TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Neuroectodermal Tumor DisGeNET Gene-Disease Associations 1.0 null orbital frontal cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.8774 NCI-H1650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.50503 blood TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051674 cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.81446 KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.894319 MAZ_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null STK4 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-X261-0126-SM-3NMD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.871187 mantle zone of m2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41615 A549_Abexinostat_100nM_72h Sci-Plex Drug Perturbation Signatures 1.0 0.0131769 PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-NFK9-0526-SM-2YUNL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23687 TUBB4B Pathway Commons Protein-Protein Interactions 1.0 null ventromedial hypothalamic nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0061 CDC37 Pathway Commons Protein-Protein Interactions 1.0 null Cerebrum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10665 lateral ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.38279 USF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE144231_2_v_7_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-OXRL-2126-SM-3NM98 GTEx Tissue Sample Gene Expression Profiles 1.0 1.99112 GSE239844_4_v_9_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE239688_2_v_5_canagliflozin_human RummaGEO Drug Perturbation Signatures 1.0 null H3K9ac_liver_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-130b TargetScan Predicted Conserved microRNA Targets 1.0 0.997906 GTEX-NFK9-0006-SM-3GACS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.931749 placenta HPA Tissue Gene Expression Profiles -1.0 -1.15573 VHL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.32755 GSE152734,GSE152735_2_v_0_pbrm1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-OOBK-0005-SM-2YUMG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.987119 caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23408 DNAJC10 Pathway Commons Protein-Protein Interactions 1.0 null PMC12354803-42003_2025_8643_MOESM2_ESM.xlsx-2w_TP63_positive-Gene_TP63 Rummagene Transcription Factor Associations 2026 1.0 null GSE188869,GSE188871_1_v_3_kat7_mouse RummaGEO Gene Perturbation Signatures 1.0 null basolateral amygdaloid nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.93914 GSE232558_0_v_2_fbxl12_human RummaGEO Gene Perturbation Signatures 1.0 null NCI-H2228 COSMIC Cell Line Gene Mutation Profiles 1.0 null COV362 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16847 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE202434,GSE202438_15_v_5_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null BT-20 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.726 Spermatozoon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.224 GTEX-U3ZN-1626-SM-4DXTZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.02756 ventrolateral prefrontal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.06511 A549_Givinostat_10µM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0071019 Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZC-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K9ac_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null primary motor cortex (area M1, area 4)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.15704 CHD7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X4XY-0008-SM-46MVL GTEx Tissue Sample Gene Expression Profiles -1.0 -1.61059 Urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K4me3_cardiac fibroblast_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null primary metabolic process GO Biological Process Annotations 2015 1.0 null GSE200673,GSE200691_1_v_5_hmga2_mouse RummaGEO Gene Perturbation Signatures 1.0 null USP5 Pathway Commons Protein-Protein Interactions 1.0 null nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.068545 Cortical amygdalar area, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.93914 TET1-21490601-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.914 GTEX-NFK9-1326-SM-3LK5I GTEx Tissue Sample Gene Expression Profiles -1.0 -1.42138 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4712-11A-02R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.931441 neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.083952 soft tissue HPA Tissue Protein Expression Profiles -1.0 -1.28913 PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-geneName_PTF1A Rummagene Transcription Factor Associations 2026 1.0 null Restless legs syndrome DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.832 VZ in hypothalamic portion Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.11401 obesity GWASdb SNP-Disease Associations 1.0 1.47287 PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5 Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE147613_1_v_0_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null JcPL part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37077 HCC56 CCLE Cell Line Gene CNV Profiles 1.0 1.64719 CTCF_GM12873_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null pituitary BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 H3K9ac_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null paraventricular nuclei, left of thalamus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.04595 HEY1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.2217 GTEX-WCDI-0005-SM-3NB2M GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0779 GSE207611,GSE207612_0_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null orbital frontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.80239 gonad TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null USF1_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE173873_4_v_6_stra8_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-POYW-0826-SM-2XCEM GTEx Tissue Sample Gene Expression Profiles 1.0 1.01282 NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38479 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3471-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TMMY-0226-SM-33HBA GTEx Tissue Sample Gene Expression Profiles -1.0 -0.831799 shell of P-DMH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.93622 GTEX-U4B1-0626-SM-3DB8L GTEx Tissue Sample Gene Expression Profiles 1.0 0.862352 H3K4me2_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null upper (rostral) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16463 YY1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null duodenum HPA Tissue Protein Expression Profiles 1.0 0.857749 PTEN_01_303 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.62092 Fetal Lung Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.02163 Prostate adenocarcinoma_PRAD_TCGA-CH-5752-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8 Rummagene Transcription Factor Associations 2026 1.0 null testis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 Testis TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 POLR2A_Raji_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JURLMK1 CCLE Cell Line Gene CNV Profiles -1.0 -1.59935 KLB Pathway Commons Protein-Protein Interactions 1.0 null PKN2 Pathway Commons Protein-Protein Interactions 1.0 null GANAB Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_endothelial cell of umbilical vein_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE163240_3_v_4_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null TTN Pathway Commons Protein-Protein Interactions 1.0 null PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4 Rummagene Transcription Factor Associations 2026 1.0 null PMC12461113-HEM3-9-e70217-s002.xlsx-Table_S3-Model_4_top_50_genes_IKZF5_IKZF5 Rummagene Transcription Factor Associations 2026 1.0 null TARBP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.14559 ACOX1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-U412-0226-SM-3NMC8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15696 TBX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.101 H3K9ac_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE65617_2_v_3_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-T5JC-0005-SM-4DM7B GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00016 GSE240468_3_v_6_nfyc_human RummaGEO Gene Perturbation Signatures 1.0 null intracellular membrane-bounded organelle GO Cellular Component Annotations 2023 1.0 null Hypopharyngeal carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.045 CAD Pathway Commons Protein-Protein Interactions 1.0 null POLR2A_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE217115_2_v_4_alectinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null SKNO1 CCLE Cell Line Gene CNV Profiles -1.0 -1.53792 Lung disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.712 periventricular stratum of isBI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18343 mediodorsal nucleus of thalamus_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.927688 u138mg HPA Cell Line Gene Expression Profiles -1.0 -0.969415 PUF60 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.26582 hippocampus (hippocampal formation)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.938058 hsa-miR-620 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 Organ system cancer DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.905 H3K4me3_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null fourth ventricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.599273 AZI2 Pathway Commons Protein-Protein Interactions 1.0 null t24/83 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.766 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE159473_0_v_1_eif5a2_human RummaGEO Gene Perturbation Signatures -1.0 null GSE125014_6_v_5_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null Response to fenofibrate (HDL cholesterol levels) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.569897 PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null Cortical plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.17897 ZKSCAN1 ENCODE Transcription Factor Targets 1.0 null H3K4me3_H1 Derived Mesenchymal Stem Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-626 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 GSE158834_7_v_13_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null rosiglitazone_mus musculus_gpl7202_gse19896 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Posterior parietal association areas, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02262 acquired metabolic disease DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.58494 H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CEBPB JASPAR Predicted Transcription Factor Targets 1.0 null POLR2A_GM19099_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_G1E_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-93 TargetScan Predicted Conserved microRNA Targets 1.0 0.419947 mRNA_DLX3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null amygdaloid complex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.966776 SQSTM1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_fibroblast of lung_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null GTEX-R55G-2526-SM-2TC6D GTEx Tissue Sample Gene Expression Profiles -1.0 -0.897271 GTEX-X5EB-2226-SM-46MW4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.2447 Acute Myeloid Leukemia_LAML_TCGA-AB-2847-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in rostral midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.20763 Islet Cell Tumor DisGeNET Gene-Disease Associations 1.0 null Parathyroid gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 dorsolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.825126 Hypothalamus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.001 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A3M9-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Nucleus of the brachium of the inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.81974 Tyrosinemia DisGeNET Gene-Disease Associations 1.0 null ZNF263 ENCODE Transcription Factor Targets 1.0 null CCT7 Pathway Commons Protein-Protein Interactions 1.0 null reticular formation of p1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.73981 H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE112761,GSE112767_4_v_5_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null internal male genital organ TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 POLR2AphosphoS5_neural cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null AP3M1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44075 PMC12559107-12035_2025_5221_MOESM1_ESM.xlsx-Supplment_Tab_3-Supplement_Tab_3_The_result_of_MR_analysis_for_SCZ_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null Bed nuclei of the stria terminalis, anterior division, anterolateral area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02658 H3K4me3_astrocyte of the cerebellum_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE102505_1_v_3_tunicamycin_human RummaGEO Drug Perturbation Signatures 1.0 null HNRNPL Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null NRF1 ENCODE Transcription Factor Targets 1.0 null GTEX-P44H-1026-SM-3NM96 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.935018 Alfuzosin DeepCoverMOA Drug Mechanisms of Action 1.0 0.33 PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_CoCl2-Unnamed_12_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H2AFZ_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.929713 Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RUVBL1 Pathway Commons Protein-Protein Interactions 1.0 null dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.926533 POLR2A_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U8XE-0326-SM-3DB8P GTEx Tissue Sample Gene Expression Profiles -1.0 -0.875365 horizontal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.831547 GTEX-X4LF-0426-SM-3NMB5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.945643 GSE216043_7_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.841686 r6 part of nucleus prepositus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11013 496100529_HIP_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.07368 primary somatosensory cortex (area S1, areas 3,1,2)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.18296 intracellular COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GSE202434,GSE202438_2_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null dorsolateral prefrontal cortex_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.859908 GTEX-UPK5-1126-SM-3GAEJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.05523 GSE158431_2_v_6_pioglitazone_mouse RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6088-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11529 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.81344 PMC12433928-12672_2025_2985_MOESM1_ESM.pdf-11-RUNX2_RUNX2 Rummagene Transcription Factor Associations 2026 1.0 null PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-130a TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 TAF1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC7305081-10120_2020_1045_MOESM1_ESM.xlsx-Tab2-Mutation-MAF_MAF Rummagene Transcription Factor Associations 2026 1.0 null POLR2AphosphoS5_neural cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null basolateral amygdaloid nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42951 DYNC1I2 Pathway Commons Protein-Protein Interactions 1.0 null Body mass index (age <50) GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.03979 primary motor cortex (area M1, area 4)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.70122 U031 COSMIC Cell Line Gene Mutation Profiles 1.0 null obesity DISEASES Experimental Gene-Disease Association Evidence Scores 1.0 0.256228 mRNA_MEF2C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null MYC_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.903609 CYP2D6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28206 GTEX-SUCS-1326-SM-4DM5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.52568 GTEX-X15G-0526-SM-3NMB7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05124 Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SREBF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9731 EOMES-21245162-HESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null RPL15 Pathway Commons Protein-Protein Interactions 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXP1_FOXP1 Rummagene Transcription Factor Associations 2026 1.0 null Central lateral nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32248 GTEX-Q734-0006-SM-2I3FJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07916 cancer GWASdb SNP-Disease Associations 1.0 0.052026 GTEX-RUSQ-2126-SM-47JXK GTEx Tissue Sample Gene Expression Profiles 1.0 1.58911 GTEX-T6MO-0226-SM-32QOL GTEx Tissue Sample Gene Expression Profiles 1.0 1.02181 GSE175787_4_v_6_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.968 Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-T8EM-0226-SM-3DB7C GTEx Tissue Sample Gene Expression Profiles 1.0 1.07685 GSE214931_2_v_5_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null hematopoietic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051432 GTEX-WHPG-0226-SM-3NMB9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.986919 KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null anion binding GO Molecular Function Annotations 2015 1.0 null some GeneRIF Biological Term Annotations 1.0 null Posterolateral visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00376 GTEX-PW2O-0006-SM-2I3DV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00489 testis_7b HPA Tissue Sample Gene Expression Profiles 1.0 1.32101 GTEX-WFG8-2226-SM-3GIL9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25618 PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2 Rummagene Transcription Factor Associations 2026 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-06A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CALCOCO2 Pathway Commons Protein-Protein Interactions 1.0 null cerebellar cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25421 GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null m1Lim part of the midbrain reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.28637 Brain Lower Grade Glioma_LGG_TCGA-FG-A4MT-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EFM-192A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.940623 chr11_8611792_G_A_b38 GTEx eQTL 2025 1.0 2.84584 E2F6_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13291 JIMT1 CCLE Cell Line Gene CNV Profiles -1.0 -2.14249 Oligoasthenoteratozoospermia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.008 Prostate adenocarcinoma_PRAD_TCGA-H9-A6BX-01A-31R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_Brain Germinal Matrix Roadmap Epigenomics Histone Modification Site Profiles 1.0 null 496100490_HIP_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.42043 monocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.083146 GTEX-OIZI-0726-SM-2XCEI GTEx Tissue Sample Gene Expression Profiles 1.0 0.990671 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.24786 PSMC5 Pathway Commons Protein-Protein Interactions 1.0 null RUNX3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null central gray substance of midbrain, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.912649 mantle zone of AStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09877 SOX2_01_349 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59535 organic cyclic compound binding GO Molecular Function Annotations 2015 1.0 null GSE175787_13_v_9_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null upper limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.11402 ASMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0372 MYBL1_KO_GDS4485_350_mouse_Testis from 17 day old GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PRKAG2 Pathway Commons Protein-Protein Interactions 1.0 null GSE88819_1_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null members GeneRIF Biological Term Annotations 1.0 null mRNA_TCF3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-WFG8-0426-SM-3GILD GTEx Tissue Sample Gene Expression Profiles 1.0 0.862591 KRT14 Pathway Commons Protein-Protein Interactions 1.0 null posteroventral (inferior) parietal cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.93587 TBP_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RARS Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_WI38_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null POLR2A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_CoCl2-Unnamed_16_HIF1A Rummagene Transcription Factor Associations 2026 1.0 null NCI-H358 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.632 THNSL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.21044 metencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.156594 H3K4me1_Brain Cingulate Gyrus Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-UPIC-0226-SM-3GADO GTEx Tissue Sample Gene Expression Profiles 1.0 1.09037 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GB-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9203705-bloodBLD2021014723-suppl2.xlsx-Supp_Table_5-Supplementary_Table_5_List_of_genes_identified_by_WGCNA_corresponding_to_the_CDX2_UBTF_cluster_CDX2 Rummagene Transcription Factor Associations 2026 1.0 null ventrolateral prefrontal cortex_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.937461 Reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K9ac_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-S33H-1626-SM-4AD68 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.831063 basolateral amygdaloid nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.30951 MEWO CCLE Cell Line Gene Mutation Profiles 1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null GSE211128_9_v_0_angptl4_human RummaGEO Gene Perturbation Signatures -1.0 null posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.909655 GTEX-XPT6-0008-SM-4B64Q GTEx Tissue Sample Gene Expression Profiles -1.0 -0.942192 FaDu cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.05 cerebellar cortex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07744 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MR-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chr11_8564142_T_G_b38 GTEx eQTL 2025 1.0 1.99149 EP300_GM12878_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKN3 DepMap CRISPR Gene Dependency 1.0 3.63618 MAX_A549_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-FX-A8OO-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null caudal ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.14017 POLR2A_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-UPIC-1826-SM-4IHKC GTEx Tissue Sample Gene Expression Profiles 1.0 0.82598 ANXA2 Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-744 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 GSE220600_1_v_2_clpp_mouse RummaGEO Gene Perturbation Signatures -1.0 null protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041062 Fer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.595 PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null PTBP1 Pathway Commons Protein-Protein Interactions 1.0 null RPN1 Pathway Commons Protein-Protein Interactions 1.0 null GSE142210_2_v_0_panobinostat_human RummaGEO Drug Perturbation Signatures 1.0 null PRPF19 Pathway Commons Protein-Protein Interactions 1.0 null primary motor-sensory cortex (samples)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.994223 NMD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.64928 PMC3889689-elife01439s001.xls-RFX2_rnaseq_chip_DirectDE_final-GeneName_RFX2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-X585-2426-SM-46MW2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29027 H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Infralimbic area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22883 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null RPL18A Pathway Commons Protein-Protein Interactions 1.0 null HCC1937 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.37636 GTEX-QCQG-1326-SM-48U24 GTEx Tissue Sample Gene Expression Profiles 1.0 0.980993 AURKA Pathway Commons Protein-Protein Interactions 1.0 null PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.987688 Acute Myeloid Leukemia_LAML_TCGA-AB-2993-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null chr11_8597314_A_G_b38 GTEx eQTL 2025 1.0 1.61385 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-6871-01A-11R-1873-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NO11 DepMap CRISPR Gene Dependency 1.0 12.1544 Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RNOR-2426-SM-48FDY GTEx Tissue Sample Gene Expression Profiles 1.0 1.49184 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null SYK Pathway Commons Protein-Protein Interactions 1.0 null GTEX-UPJH-0126-SM-4IHLL GTEx Tissue Sample Gene Expression Profiles 1.0 1.52369 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ERG_ERG Rummagene Transcription Factor Associations 2026 1.0 null ALKBH6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.33495 kinase GeneRIF Biological Term Annotations 1.0 null GTEX-PWO3-0011-R6A-SM-2I5F3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.17111 H3K4me3_CD3 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null MDAMB231 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.45515 Bone marrow cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.113 ZKSCAN3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 58.7762 496100618_PCx_probable Alzheimer's disease_no TBI_86_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.21998 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 KANSL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01821 PMC6683136-41598_2019_47363_MOESM2_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1-AS1_and_other_genes_ZEB1 Rummagene Transcription Factor Associations 2026 1.0 null Squamous cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.391 GTEX-TKQ2-1726-SM-4DXUP GTEx Tissue Sample Gene Expression Profiles -1.0 -0.959182 GTEX-UTHO-0006-SM-3NMCC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.67527 ribonucleoside binding GO Molecular Function Annotations 2015 1.0 null GSE234514,GSE234516_2_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null kidney HPA Tissue Protein Expression Profiles -1.0 -0.896424 NAMALWA cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.726 PcPL part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.05481 BHLHE40_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Agranular insular area, ventral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5756 r8 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.45711 PSMA7 Pathway Commons Protein-Protein Interactions 1.0 null MAX_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC7495487-41598_2020_71030_MOESM2_ESM.xlsx-Sheet1-NR1A1_THRA Rummagene Transcription Factor Associations 2026 1.0 null STK33_SKM MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null Manchette COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 4.0 hsa-miR-17 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Sox3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.9412 ELF1 ENCODE Transcription Factor Targets 1.0 null GTEX-OHPM-0006-SM-2HMKU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.05464 HPDL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.42671 Neck TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GSE154074_5_v_0_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null purine nucleotide binding GO Molecular Function Annotations 2015 1.0 null hsa-miR-372 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 CTCF_thymus_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE98898_8_v_1_hoxa1_human RummaGEO Gene Perturbation Signatures -1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CM-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X5EB-0006-SM-46MV5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.01659 H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE186647,GSE217288_11_v_7_hnrnpc_human RummaGEO Gene Perturbation Signatures -1.0 null COPB2 Pathway Commons Protein-Protein Interactions 1.0 null pineal body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32819 H3K27me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE158834_2_v_8_palmitic acid_human RummaGEO Drug Perturbation Signatures -1.0 null SK-MEL-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null Perturb_18111_KO_Eed_SRP132909 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.52366 ILF2 Pathway Commons Protein-Protein Interactions 1.0 null GSE90710_1_v_0_med13_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XAJ8-0926-SM-47JXZ GTEx Tissue Sample Gene Expression Profiles -1.0 -0.873433 SF3B4 Pathway Commons Protein-Protein Interactions 1.0 null Postpiriform transition area, layers 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07245 GTEX-RNOR-0926-SM-2TF56 GTEx Tissue Sample Gene Expression Profiles 1.0 0.857975 GSE122101,GSE122103_3_v_4_ssu72_mouse RummaGEO Gene Perturbation Signatures 1.0 null lateropallial amygdalopiriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.07624 GTEX-XBED-2026-SM-4AT5D GTEx Tissue Sample Gene Expression Profiles 1.0 1.54549 H3K36me3_MEL cell line_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null arteriosclerosis GWASdb SNP-Phenotype Associations 1.0 0.261361 Pancreatic ductal carcinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.04 lateral ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.7228 Axonemal dynein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.127 mRNA_FOXJ2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null USF1_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10794847-mmc5.xlsx-PIAS1_KD_down-Table_S4_Differentially_expressed_genes_with_PIAS1_knockdown_in_the_progenitors_state_Related_to_Figure_5_AR Rummagene Transcription Factor Associations 2026 1.0 null orbital frontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.907619 COL8A1 Pathway Commons Protein-Protein Interactions 1.0 null Septohippocampal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27921 RARA::RXRG JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.9948 GTEX-WWYW-0005-SM-3NB3K GTEx Tissue Sample Gene Expression Profiles -1.0 -1.67315 Malignant Neoplasm DisGeNET Gene-Disease Associations 1.0 null organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039828 GTEX-XLM4-0726-SM-4AT64 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13172 RUVBL2 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-QEL4-0526-SM-3GIJ4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25633 ventrolateral prefrontal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.978785 HNFA-21074721-CACO-2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Infundibulum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.076 GTEX-RM2N-1326-SM-48FCW GTEx Tissue Sample Gene Expression Profiles 1.0 1.65249 female reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GSE167984,GSE167987_0_v_1_setd1b_mouse RummaGEO Gene Perturbation Signatures 1.0 null mRNA_ESX1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-OIZH-2126-SM-3NB1P GTEx Tissue Sample Gene Expression Profiles 1.0 1.90852 MKN-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.984984 LP1 CCLE Cell Line Gene Expression Profiles 1.0 1.35018 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null TBL1XR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null inner CP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10808 Body mass index in physically active individuals GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.7 dentate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.9891 LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null mRNA_RHOX6_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PSMC4 Pathway Commons Protein-Protein Interactions 1.0 null colo320hsr TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.165 HCC2270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.38152 DLD-1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.328 GTEX-N7MS-2625-SM-3LK77 GTEx Tissue Sample Gene Expression Profiles 1.0 1.30175 Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HUWE1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22865 H3K4me3_GM12878_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null urinary bladder HPA Tissue Protein Expression Profiles 1.0 0.857749 H3K9ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null HELLS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.31756 dorsal part of JcP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46932 GSE175787_5_v_9_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null SUZ12-20075857-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-SN8G-0126-SM-32PLI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00167 insular cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05003 golgi apparatus COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 hsa-miR-4714-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-SOX2-M_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null EFM-192B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.896129 ZNF692 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.9572 ventrolateral prefrontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.925307 GSE158834_10_v_8_palmitic acid_human RummaGEO Drug Perturbation Signatures -1.0 null intermediate stratum of isLim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51613 NCIN87 DepMap CRISPR Gene Dependency 1.0 4.28022 USF1_A549_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventrolateral part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41652 primary auditory cortex (core)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.846931 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.971815 XMD8-85 LINCS KinomeScan Kinase Inhibitor Targets 1.0 0.883492 BC-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XMD1-0006-SM-4AT4Q GTEx Tissue Sample Gene Expression Profiles -1.0 -1.51517 GSE216043_7_v_8_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null CFPAC-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.851587 H3K4me3_Stomach Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null protein phosphorylation GO Biological Process Annotations 2015 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LC-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null paraventricular nuclei, right of thalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.38886 GTEX-WY7C-0226-SM-3NB37 GTEx Tissue Sample Gene Expression Profiles 1.0 0.851667 RPS12 Pathway Commons Protein-Protein Interactions 1.0 null NB7 COSMIC Cell Line Gene Mutation Profiles 1.0 null POLR2AphosphoS5_HCT116_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QEG5-0326-SM-2S1PB GTEx Tissue Sample Gene Expression Profiles -1.0 -0.945186 GTEX-RWS6-2326-SM-2XCB4 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27525 SNRPD3 Pathway Commons Protein-Protein Interactions 1.0 null mutant GeneRIF Biological Term Annotations 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040898 Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HOXA5 JASPAR Predicted Transcription Factor Targets 1.0 null hsa-miR-519d TargetScan Predicted Conserved microRNA Targets 1.0 0.49473 chr11_8557534_T_A_b38 GTEx eQTL 2025 1.0 1.66235 RPS28 Pathway Commons Protein-Protein Interactions 1.0 null SERPINB12 Pathway Commons Protein-Protein Interactions 1.0 null TP63-22573176-HFKS-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null PML_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC4821877-ncomms10846-s9.xlsx-THP1_Splice_events-Gene_GLI2 Rummagene Transcription Factor Associations 2026 1.0 null PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-146-ZNF225_ZNF225 Rummagene Transcription Factor Associations 2026 1.0 null medial ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.07954 T-T COSMIC Cell Line Gene Mutation Profiles 1.0 null NCIH2286 CCLE Cell Line Gene Expression Profiles 1.0 1.59338 TPR Pathway Commons Protein-Protein Interactions 1.0 null primary motor cortex (area M1, area 4)_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.942245 GSE202434,GSE202438_6_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.20191 SKIV2L2 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_fibroblast of lung_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GSE48812_3_v_6_sulforaphane_human RummaGEO Drug Perturbation Signatures 1.0 null inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.14239 abnormal sperm flagellum morphology MGI Mouse Phenotype Associations 2023 1.0 null protein autophosphorylation GO Biological Process Annotations 2025 1.0 null PSMD12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -4.05324 KAP1-22055183-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Respiratory system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.792 Acute Myeloid Leukemia_LAML_TCGA-AB-2983-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null testis TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 organ system cancer GWASdb SNP-Disease Associations 1.0 0.05534 GSE206516,GSE206518_6_v_4_ptdss2_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XMD1-0011-R5A-SM-4AT47 GTEx Tissue Sample Gene Expression Profiles 1.0 1.10571 ependymocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.236725 trochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08783 GTEX-NPJ8-0007-SM-2D7VX GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 GSE195568_3_v_0_palbociclib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE216043_11_v_1_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null protein modification process GO Biological Process Annotations 2015 1.0 null GTEX-S7SE-0326-SM-4AT5Q GTEx Tissue Sample Gene Expression Profiles 1.0 1.71581 GTEX-XGQ4-0426-SM-4AT4I GTEx Tissue Sample Gene Expression Profiles 1.0 1.02703 GSE214583,GSE214585_1_v_0_steap1_human RummaGEO Gene Perturbation Signatures 1.0 null CTCF_MEL cell line_mm9_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1569 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.878868 Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7Q0-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NRF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ALDH3A2 Pathway Commons Protein-Protein Interactions 1.0 null LARP1 Pathway Commons Protein-Protein Interactions 1.0 null Finding Of Body Mass Index DisGeNET Gene-Phenotype Associations 1.0 null nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.073244 Notochordal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.242 GTEX-XBEW-0126-SM-4AT66 GTEx Tissue Sample Gene Expression Profiles 1.0 1.23878 H3K27ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.489852 JUP Pathway Commons Protein-Protein Interactions 1.0 null GSE247084,GSE247087_0_v_1_cdyl_human RummaGEO Gene Perturbation Signatures 1.0 null A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_18Hour_None_GSE43204 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.74801 H3K4me3_Adipose Nuclei Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TUBB Pathway Commons Protein-Protein Interactions 1.0 null Large Cell Carcinoma Of Lung DisGeNET Gene-Disease Associations 1.0 null TBL1-22424771-293T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null those GeneRIF Biological Term Annotations 1.0 null RFX5_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null chr11_8596003_C_T_b38 GTEx eQTL 2025 1.0 4.03984 Urinary system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.125 LGALS3BP Pathway Commons Protein-Protein Interactions 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8437-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MKN-45 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.747 GSE162590_1_v_0_gsx2_mouse RummaGEO Gene Perturbation Signatures -1.0 null intracellular membrane-bounded organelle GO Cellular Component Annotations 2025 1.0 null primary auditory cortex (core)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.977677 PRKCD Pathway Commons Protein-Protein Interactions 1.0 null PAX5_GM12892_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE202603_1_v_2_bhlhe40_mouse RummaGEO Gene Perturbation Signatures -1.0 null HNRNPDL Pathway Commons Protein-Protein Interactions 1.0 null Ebolavirus(ZEBOV)_1day_Spleen_None_GSE57214 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.76003 GSE140441_2_v_0_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null EEF1B2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34337 Neuroblastoma DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.905 ventral isthmic part of dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41285 PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null Field CA3, stratum radiatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16751 CUX1 ENCODE Transcription Factor Targets 1.0 null MCF-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.40635 GTEX-SN8G-0006-SM-32PLD GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23134 non-Hodgkin lymphoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.051 Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q3-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EEF1D Pathway Commons Protein-Protein Interactions 1.0 null laterorostral part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07042 Hypertrophy CTD Gene-Disease Associations 1.0 1.31267 adult stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.061143 GTEX-WFON-2026-SM-4LVMW GTEx Tissue Sample Gene Expression Profiles 1.0 1.14853 Perturb_14796_OE_Mycn_SRP094656 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.89559 MDA-MB-134-VI Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.869746 GSE158834_1_v_8_palmitic acid_human RummaGEO Drug Perturbation Signatures -1.0 null basomedial amygdaloid nucleus, posterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.82839 SRPRA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22046 GSE158834_0_v_8_palmitic acid_human RummaGEO Drug Perturbation Signatures -1.0 null hsa-miR-527 TargetScan Predicted Conserved microRNA Targets 1.0 0.49473 GTEX-X638-0005-SM-47JX6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00239 protein autophosphorylation GO Biological Process Annotations 2023 1.0 null hsa-miR-3666 TargetScan Predicted Conserved microRNA Targets 1.0 0.997906 GSE121198,GSE129782_1_v_0_arid1a_human RummaGEO Gene Perturbation Signatures -1.0 null STAT1 ENCODE Transcription Factor Targets 1.0 null FUOV1 CCLE Cell Line Gene CNV Profiles 1.0 1.80943 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LF-01A-21R-A22U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U8T8-2326-SM-3DB96 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03491 RPL5 Pathway Commons Protein-Protein Interactions 1.0 null EIF3L Pathway Commons Protein-Protein Interactions 1.0 null heterocyclic compound binding GO Molecular Function Annotations 2015 1.0 null TTLL11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.23324 GSE148657_3_v_0_cd44_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_GM12864_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null outer CP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.27714 KYSE-270 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.839816 intracellular part GO Cellular Component Annotations 2015 1.0 null HS281T CCLE Cell Line Gene Mutation Profiles 1.0 null MOTN1 CCLE Cell Line Gene CNV Profiles -1.0 -1.38863 CDC5L Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_GM12865_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE173910,GSE173917_1_v_0_morc3_mouse RummaGEO Gene Perturbation Signatures 1.0 null Tonsil TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 Retrosplenial area, dorsal part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38922 NCIH2286 CCLE Cell Line Gene CNV Profiles 1.0 1.33877 Dorsomedial nucleus of the hypothalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17376 ERF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4254 AP5Z1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19305 Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CEBPB-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-RM2N-1926-SM-48FCU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29996 GATA1 JASPAR Predicted Transcription Factor Targets 1.0 null JIMT-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.30961 GTEX-T6MN-2726-SM-4DM77 GTEx Tissue Sample Gene Expression Profiles 1.0 1.66139 TBX5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.0944 FOXM1 ENCODE Transcription Factor Targets 1.0 null SAS COSMIC Cell Line Gene Mutation Profiles 1.0 null USF1_A549_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE190316,GSE190324_6_v_9_rbm4_human RummaGEO Gene Perturbation Signatures 1.0 null outer CP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10441 PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_9_CCF-Affected_Genes_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_endothelial cell of umbilical vein_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null posteroventral (inferior) parietal cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.31988 epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055362 GTEX-WH7G-1126-SM-3NMBK GTEx Tissue Sample Gene Expression Profiles -1.0 -0.889242 T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.12718 GTEX-REY6-1226-SM-48FDR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.828079 GTF2I Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_fibroblast of the aortic adventitia_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null mediodorsal nucleus of thalamus_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.842324 Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.43565 H3K4me2_B cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null nucleus GO Cellular Component Annotations 2023 1.0 null GSE207787_3_v_2_pdha1_human RummaGEO Gene Perturbation Signatures -1.0 null KRT7 Pathway Commons Protein-Protein Interactions 1.0 null Prostate disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.014 polysensory temporal cortex (area 22p) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12466 KMRC2 CCLE Cell Line Gene CNV Profiles 1.0 3.2803 TCC-PAN2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.908463 Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H2-01A-12R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-V955-1926-SM-4KL1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.54787 PMC3579516__F7 PFOCR Pathway Figure Associations 2023 1.0 null Retrosplenial area, lateral agranular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24391 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81G-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ovarian surface epithelial cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.57 intermediate stratum of m2AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25199 amygdalohippocampal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18182 H3K4me3_brain microvascular endothelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE154074_2_v_4_bleomycin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Posterior hypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01625 H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null USF1_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_heart_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K9ac_Adult Kidney Roadmap Epigenomics Histone Modification Site Profiles 1.0 null anaphase-promoting complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.731 NSUN2 Pathway Commons Protein-Protein Interactions 1.0 null obesity GeneRIF Biological Term Annotations 1.0 null DB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.908463 PMC10800016-table_s3_20230913_ddad186.xlsx-DUX4-aff_I-Unnamed_1_DUX4 Rummagene Transcription Factor Associations 2026 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RC3H2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.50526 Female reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 primary auditory cortex (core)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.1078 RPL18 Pathway Commons Protein-Protein Interactions 1.0 null subcutaneous adipose tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.459532 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A5U2-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE225901_2_v_3_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null Cytoplasmic vesicle lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.686 GTEX-XUZC-1726-SM-4BRWS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.43386 RPS6KA6 Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular process GO Biological Process Annotations 2015 1.0 null RCOR1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3453-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inner portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.864266 hsa-miR-183-5p MiRTarBase microRNA Targets 1.0 null H3K4me3_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE218819_3_v_4_kdm5b_human RummaGEO Gene Perturbation Signatures 1.0 null Internal male genital organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-CA-ID_PTF1A Rummagene Transcription Factor Associations 2026 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2895-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-885-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 GSE121824,GSE121826_0_v_6_scaf8_human RummaGEO Gene Perturbation Signatures 1.0 null GSE138863_2_v_1_disulfiram_human RummaGEO Drug Perturbation Signatures -1.0 null Central amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06474 CTCF_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KMS-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.830353 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053085 cerebellar cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.914845 Hyperplasia CTD Gene-Disease Associations 1.0 1.16933 intermediate stratum of PHyB-V Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.79279 RARA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 68.3965 H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-U412-0426-SM-3DB9O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.98983 GSE178292_0_v_3_melphalan_human RummaGEO Drug Perturbation Signatures -1.0 null HSCC cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.397 anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.25253 GTEX-T6MO-1626-SM-32QOM GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 GTEX-QCQG-1826-SM-2S1P2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.902164 EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-Y8E5-0006-SM-47JWQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.26543 IF-87-AU84_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.246139 H3K4me2_CH12.LX_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null substance-related disorder GWASdb SNP-Disease Associations 1.0 0.205479 CHD2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null THRA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12616 RPS18 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TEKTIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.02369 medial amygdala, anteroventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16478 ventrolateral prefrontal cortex_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.01102 Chaperone complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.032 GTEX-P78B-1326-SM-3P611 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.856611 hsa-miR-4640-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 MTA3 ENCODE Transcription Factor Targets 1.0 null GTEX-X5EB-1926-SM-4E3IW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.59752 area postrema TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.79146 SUZ12-20075857-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null USF1_SK-N-SH_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WHWD-2426-SM-3LK6S GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17753 H3K4me3_Panc1_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GPRC5A Pathway Commons Protein-Protein Interactions 1.0 null PAPSS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.21555 GSE108084_3_v_2_epinephrine_human RummaGEO Drug Perturbation Signatures 1.0 null GSE210655_3_v_7_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null GTEX-RTLS-0226-SM-2TF5E GTEx Tissue Sample Gene Expression Profiles -1.0 -1.55307 GSE157960_0_v_3_progesterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null H2BK20ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Pancreatic carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.216 Dentate gyrus, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31601 H3K4me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE178532_2_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null embryonic stem no feeder BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.14529 H3K4me3_HeLa-S3_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE142684_3_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null Male reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.01 LRRK2 Pathway Commons Protein-Protein Interactions 1.0 null primary motor-sensory cortex (samples)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.973365 hsa-miR-324-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 core part of DTg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.49654 RT11284 CCLE Cell Line Gene CNV Profiles -1.0 -1.41132 OPM2 CCLE Cell Line Gene Expression Profiles 1.0 1.88793 mantle zone of VAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51365 FER Pathway Commons Protein-Protein Interactions 1.0 null head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.070397 YY1 ENCODE Transcription Factor Targets 1.0 null OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.49128 H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KRT18 Pathway Commons Protein-Protein Interactions 1.0 null r7 portion of the hypoglossal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.59976 BRCA1 ENCODE Transcription Factor Targets 1.0 null SUIT-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null sense organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.069494 Serous carcinoma_Fallopian tube_GSE10971 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.77087 H3K4me3_Caco-2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.908748 EIF3E Pathway Commons Protein-Protein Interactions 1.0 null brain ventricle TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.223906 Central amygdalar nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07245 UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_Neurosphere Cultured Cells Cortex Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-X4XY-0006-SM-46MV2 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17388 raphe obscurus nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.89027 CENPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13208 POLR2A_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EZH2_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC11993713-41598_2025_96655_MOESM1_ESM.xlsx-S10-Table_S10_MR_results_of_the_discovery_blood_cis-eQTLs_and_Sepsis_outcomes_in_IVW_or_Wald_ratio_methods_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null GSE148010,GSE148120_3_v_2_tet2_human RummaGEO Gene Perturbation Signatures -1.0 null occipito-temporal gyrus, right, superior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.867479 496100438_PCx_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.76936 PANC-08-13 COSMIC Cell Line Gene Mutation Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KO-8410-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE139016_3_v_2_disulfiram_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-OIZH-2626-SM-2HMJM GTEx Tissue Sample Gene Expression Profiles 1.0 0.8566 POLR2A_GM15510_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_ETV3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null hsa-miR-518a-5p TargetScan Predicted Conserved microRNA Targets 1.0 0.49473 NCL Pathway Commons Protein-Protein Interactions 1.0 null 496100470_HIP_possible Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.52295 PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S11-DUX4_DiffExprGene-Unnamed_1_DUX4 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-P4PP-0005-SM-2HMKX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.19896 NVP-BEP800 DeepCoverMOA Drug Mechanisms of Action -1.0 -1.39 GSE88819_1_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-TSE9-3126-SM-4DXSY GTEx Tissue Sample Gene Expression Profiles 1.0 1.29894 SARS-CoV MA15_Day2_None_GSE49262 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.43914 H3K4me3_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null alar plate of evaginated telencephalic vesicle Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07245 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.20033 H3K4me3_fibroblast of gingiva_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Genetic Predisposition to Disease HuGE Navigator Gene-Phenotype Associations 1.0 null PML_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XV7Q-0626-SM-4BRV5 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.970671 GSE164874_5_v_0_prednisolone_human RummaGEO Drug Perturbation Signatures 1.0 null phosphorylation GO Biological Process Annotations 2015 1.0 null hsa-miR-520c-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 GTEX-Q2AG-3026-SM-48U1L GTEx Tissue Sample Gene Expression Profiles 1.0 1.45694 H3K4me1_K562_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.158 GSE144231_2_v_1_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null RPL11 Pathway Commons Protein-Protein Interactions 1.0 null GSE158197_0_v_4_egfr_mouse RummaGEO Gene Perturbation Signatures -1.0 null SCX CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.63893 LMNA Pathway Commons Protein-Protein Interactions 1.0 null trunk TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.056131 abnormality of the coronary arteries GWASdb SNP-Phenotype Associations 1.0 0.29639 Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-3467-01A-02R-1351-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SF3B1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null HDAC6 Pathway Commons Protein-Protein Interactions 1.0 null Gli2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.7628 cytoplasmic part GO Cellular Component Annotations 2015 1.0 null amygdaloid complex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.61708 CAMK2D Pathway Commons Protein-Protein Interactions 1.0 null EOMES-21245162-HESC-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPS6KA3 Pathway Commons Protein-Protein Interactions 1.0 null PMC5652794__F8 PFOCR Pathway Figure Associations 2024 1.0 null H3K27me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Diencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.001 female reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-WFON-0005-SM-3NMC9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.71112 A549_Abexinostat_1µM_72h Sci-Plex Drug Perturbation Signatures 1.0 0.0121561 SPTBN1 Pathway Commons Protein-Protein Interactions 1.0 null GSE183994_1_v_0_scml2_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-XUZC-2026-SM-4BRW9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.58936 Hematologic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.442 GSE216043_3_v_6_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-XMK1-0626-SM-4B65A GTEx Tissue Sample Gene Expression Profiles 1.0 0.921922 XPO1 Pathway Commons Protein-Protein Interactions 1.0 null Pancreatic adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.248 COPA Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_WI38_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Nematocyst COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.682 H3K27me3_erythroblast_mm9_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Sarcoma_SARC_TCGA-FX-A76Y-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_bronchial epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Fruit consumption GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.804576 GSE100863,GSE100864_3_v_0_tet2_mouse RummaGEO Gene Perturbation Signatures 1.0 null HCC1143 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.745839 KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17038 POLR2AphosphoS5_GM12891_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-U3ZN-0006-SM-3DB7Y GTEx Tissue Sample Gene Expression Profiles -1.0 -0.883086 NFIC ENCODE Transcription Factor Targets 1.0 null PRPF8 Pathway Commons Protein-Protein Interactions 1.0 null GSE95771_0_v_3_ruxolitinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null skin TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06216 RPS26 Pathway Commons Protein-Protein Interactions 1.0 null NQO2 Pathway Commons Protein-Protein Interactions 1.0 null SARS-CoV MA15_Day7-PFU-10^5_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.11491 PPP2R3C CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.99088 POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null A549_Epothilone A_10µM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0131432 MDA-MB-330 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26386 MFN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.25696 GTEX-NL3H-0006-SM-2I3FW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12692 Skin Cutaneous Melanoma_SKCM_TCGA-EB-A85I-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PIM1 Pathway Commons Protein-Protein Interactions 1.0 null primary auditory cortex (core)_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.89157 PMC9894241-pnas.2211429119.sd05.xlsx-G2_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null GSE182179_0_v_3_kdsr_human RummaGEO Gene Perturbation Signatures 1.0 null protein serine/threonine kinase activity GO Molecular Function Annotations 2025 1.0 null inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.59936 GTEX-XQ8I-0006-SM-4BOQ5 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.52653 NCI-H358 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13253 myeloid progenitor cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.069359 496100545_HIP_possible Alzheimer's disease_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.37043 Lung adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.464 GSE175787_13_v_7_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_GATA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GSE206516,GSE206518_1_v_4_ptdss2_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-S341-1326-SM-4AD72 GTEx Tissue Sample Gene Expression Profiles 1.0 0.868584 Cloneh TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.692 LSS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.09929 GTEX-U3ZN-0726-SM-4DXT5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.02596 H3K27me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PANC0327 DepMap CRISPR Gene Dependency 1.0 22.7519 USF1 ENCODE Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC4221415__F5 PFOCR Pathway Figure Associations 2023 1.0 null PMC10568675-JCMM-27-3157-s003.docx-70-RFX3_RFX3 Rummagene Transcription Factor Associations 2026 1.0 null stratum pyramidale of caudal CA1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.916964 GTEX-Q2AI-1326-SM-2S1PL GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 Male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 SRF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2864 CREB1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPL30 Pathway Commons Protein-Protein Interactions 1.0 null Cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.973 H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac muscle cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null PMC11518656-ADHM-13-0-s002.pdf-96-MEIS1_MEIS1 Rummagene Transcription Factor Associations 2026 1.0 null MYC_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null purine ribonucleoside binding GO Molecular Function Annotations 2015 1.0 null anterior olfactory area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22883 ZNF382 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.4278 GNB2L1 Pathway Commons Protein-Protein Interactions 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null ventrolateral prefrontal cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.84894 CDK3 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RF-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2A_GM18526_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1 Rummagene Transcription Factor Associations 2026 1.0 null Adenocarcinoma DisGeNET Gene-Disease Associations 1.0 null MAX_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WVLH-3126-SM-3MJGA GTEx Tissue Sample Gene Expression Profiles 1.0 2.00793 H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null HPAFII DepMap CRISPR Gene Dependency 1.0 3.59388 GTEX-X62O-1626-SM-46MW9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.17069 swedish GeneRIF Biological Term Annotations 1.0 null LASV_FML29 _4hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.3675 lateral ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14928 Tumor Cell Invasion DisGeNET Gene-Phenotype Associations 1.0 null Bone marrow disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.108 JHUEM7 CCLE Cell Line Gene Mutation Profiles 1.0 null MXI1_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.08757 PMC6344081-elife-40364-supp8.xlsx-PLZF-Si-diff-expressed-genes-Up-Symbol_ZBTB16 Rummagene Transcription Factor Associations 2026 1.0 null Malignant astrocytoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.125 GSE196699_2_v_1_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WHSE-0126-SM-3NMBT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.904117 GTEX-TML8-0926-SM-4DXSJ GTEx Tissue Sample Gene Expression Profiles 1.0 0.903841 GTEX-QEG4-0126-SM-48TZE GTEx Tissue Sample Gene Expression Profiles 1.0 2.21885 Posterior amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33518 anterior cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24391 H3K4me1_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null medial subhabenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.017 GTEX-U3ZH-0626-SM-4DXT3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.31418 USF1_A549_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHD4-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO ChEA Transcription Factor Targets 2022 1.0 null E2F4-21247883-LYMPHOBLASTOID-HUMAN ChEA Transcription Factor Targets 2022 1.0 null TPGS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.10064 GTEX-TKQ1-0126-SM-33HB3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.971404 GTEX-QEL4-0726-SM-3GIJ5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13507 PBX-27287812-CHIP-SEQ-EMBYONIC-LIMB-MOUSE ChEA Transcription Factor Targets 2022 1.0 null H3K27me3_erythroblast_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_keratinocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QLQ7-0726-SM-2I5G2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.835037 substance dependence GWASdb SNP-Disease Associations 1.0 0.330135 GSE224096_3_v_0_cocaine_human RummaGEO Drug Perturbation Signatures -1.0 null tail of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.877723 RPS16 Pathway Commons Protein-Protein Interactions 1.0 null MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2268 CAKI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.908463 Glioblastoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.128 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39924 JUN_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null SKMEL3 CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-T6MN-0005-SM-32PLJ GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 GSE162688_1_v_2_pink1_mouse RummaGEO Gene Perturbation Signatures -1.0 null ZNF382 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.00085 GSE200839,GSE233826_5_v_4_tnrc18_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-WY7C-0006-SM-3NB3L GTEx Tissue Sample Gene Expression Profiles -1.0 -1.74385 CBX8 ENCODE Transcription Factor Targets 1.0 null POLR2A_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null superficial dorsofrontal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20825 SLC16A7+ cell_Lung_Human CellMarker Gene-Cell Type Associations 1.0 null Leukemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.31 cytoskeleton COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.074576 BHLHE22 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5757 H3K9ac_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Kdm1a_KD_GDS5055_274_mouse_3T3-L1 preadipocytes - 24h GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE88819_6_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Axoneme COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.352 NCI-H2135 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-TSE9-0005-SM-4DXUF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.46848 PUF60 Pathway Commons Protein-Protein Interactions 1.0 null preoptic BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.959223 GSE145628,GSE145629_1_v_0_myrf_human RummaGEO Gene Perturbation Signatures -1.0 null H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EIF3I Pathway Commons Protein-Protein Interactions 1.0 null APAF1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.15336 PMC7899648-elife-61630-supp2.xlsx-Blad1-Subset_of_TFE3_targets_upregulated_in_FLCNNEG_RPTEC_cluster_3_boxed_yellow_in_Figure_3A_TFE3 Rummagene Transcription Factor Associations 2026 1.0 null GSE70935_3_v_5_cyfip1_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null EA-39-YN88_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.243063 MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hippocampus (hippocampal formation)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.40671 hsa-miR-15a TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 SF3B2 Pathway Commons Protein-Protein Interactions 1.0 null MATR3 Pathway Commons Protein-Protein Interactions 1.0 null COLO-668 COSMIC Cell Line Gene Mutation Profiles 1.0 null atp binding GO Molecular Function Annotations 2015 1.0 null Alimentary canal TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Prostate adenocarcinoma_PRAD_TCGA-TK-A8OK-01A-22R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.833619 SNRPE Pathway Commons Protein-Protein Interactions 1.0 null Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null medial intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.950963 reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 EFR3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15799 Olfactory areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.223 cytosol COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 RPS2 Pathway Commons Protein-Protein Interactions 1.0 null intermediate stratum of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10614 hsa-miR-519b-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.37496 MARK4 Pathway Commons Protein-Protein Interactions 1.0 null GSE175787_8_v_6_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null hilus of the DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30316 testis_7a HPA Tissue Sample Gene Expression Profiles 1.0 1.04586 GSE100464,GSE100465_1_v_3_atrx_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-OHPM-2126-SM-3LK75 GTEx Tissue Sample Gene Expression Profiles 1.0 1.75701 organic substance metabolic process GO Biological Process Annotations 2015 1.0 null lateral subhabenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22509 GSE178292_0_v_2_melphalan_human RummaGEO Drug Perturbation Signatures -1.0 null TCF12 ENCODE Transcription Factor Targets 1.0 null HCC70 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.81765 obesity; asthma GAD Gene-Disease Associations 1.0 null GTEX-RUSQ-0326-SM-47JWS GTEx Tissue Sample Gene Expression Profiles -1.0 -0.87706 GLYCTK Pathway Commons Protein-Protein Interactions 1.0 null primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.961844 striatal amygdala Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09877 ZNF341 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6653 GTEX-XUJ4-1826-SM-4BOOU GTEx Tissue Sample Gene Expression Profiles -1.0 -1.25412 PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Supplementary_Figure_15l-FOSL2_ChIP_WT-exclusive_genes_FOSL2 Rummagene Transcription Factor Associations 2026 1.0 null Ltk TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.664 UBC Pathway Commons Protein-Protein Interactions 1.0 null PSME3IP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.28773 PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-d-Classification_of_camel_SON_basal_genes_-_enzymes_SON Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_kidney epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GSE188870,GSE188871_0_v_3_kat7_mouse RummaGEO Gene Perturbation Signatures -1.0 null RBBP5 ENCODE Transcription Factor Targets 1.0 null periventricular stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.82162 RPS6KA1 Pathway Commons Protein-Protein Interactions 1.0 null skeletal muscle HPA Tissue Protein Expression Profiles -1.0 -2.3529 USF2 JASPAR Predicted Transcription Factor Targets 1.0 null INTS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.72313 skin GTEx Tissue Gene Expression Profiles -1.0 -0.837667 male reproductive system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.964252 PMC9894241-pnas.2211429119.sd05.xlsx-G7_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST Rummagene Transcription Factor Associations 2026 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-VUSG-0426-SM-3GIKD GTEx Tissue Sample Gene Expression Profiles 1.0 1.04779 dorsolateral isthmic part of the dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27409 H3K4me2_osteoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null brain stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.14468 Primitive neuroectodermal tumor cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.054 XRN2 Pathway Commons Protein-Protein Interactions 1.0 null ChIP_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null H3K4me3_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-QESD-2026-SM-447BI GTEx Tissue Sample Gene Expression Profiles -1.0 -1.46549 GSE142210_4_v_0_panobinostat_human RummaGEO Drug Perturbation Signatures 1.0 null EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GAPDH Pathway Commons Protein-Protein Interactions 1.0 null Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.26612 colon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.306444 male reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GTEX-S32W-2126-SM-2XCB1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.46545 Cortical amygdalar area, anterior part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04249 MARK3 Pathway Commons Protein-Protein Interactions 1.0 null GSE151829,GSE151831_5_v_8_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null Agranular insular area, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63281 H3K4me3_fibroblast of foreskin _hg19_2 ENCODE Histone Modification Site Profiles 1.0 null vascular disease GWASdb SNP-Disease Associations 1.0 0.080574 GSE154253_1_v_0_tnfaip8_human RummaGEO Gene Perturbation Signatures 1.0 null PRPF4 Pathway Commons Protein-Protein Interactions 1.0 null Female reproductive organ cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.004 HNRNPA2B1 Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-4446-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 NCIH1915 CCLE Cell Line Gene CNV Profiles 1.0 2.06196 peritoneal cavity TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.289582 H3K27me3_spleen_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSS CCLE Cell Line Gene CNV Profiles 1.0 2.59998 GTEX-W5WG-1826-SM-4KL2Y GTEx Tissue Sample Gene Expression Profiles -1.0 -1.3958 H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041296 NPIPA3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04417 hsa-miR-17 TargetScan Predicted Conserved microRNA Targets 1.0 0.454769 H3K27ac_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-43-7658-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE239844_7_v_9_crizotinib_human RummaGEO Drug Perturbation Signatures 1.0 null intermediate stratum of m2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.19364 CK2A2 Kinase Library Serine Threonine Kinome Atlas 1.0 null orbital frontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.844512 PMC2866657-pone.0010547.s003.xls-ESE3_corr-Genes_correlated_anticorrelated_to_ESE3_EHF Rummagene Transcription Factor Associations 2026 1.0 null Thoracic cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.388 CTCF_GM12875_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZBTB7A ENCODE Transcription Factor Targets 1.0 null GTEX-S7PM-0626-SM-4AD4Q GTEx Tissue Sample Gene Expression Profiles 1.0 2.12596 Lung squamous cell carcinoma_LUSC_TCGA-68-8251-01A-11R-2296-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MFE-319 COSMIC Cell Line Gene Mutation Profiles 1.0 null growth abnormality GWASdb SNP-Phenotype Associations 1.0 1.30781 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null MDA-MB-453 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.837 H3K27me3_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null phosphotransferase activity, alcohol group as acceptor GO Molecular Function Annotations 2015 1.0 null EIF3C Pathway Commons Protein-Protein Interactions 1.0 null primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.19313 USF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Mobilized CD34 Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.14713 nucleoside binding GO Molecular Function Annotations 2015 1.0 null GTEX-OIZH-1826-SM-2YUNP GTEx Tissue Sample Gene Expression Profiles -1.0 -1.26079 Bed nuclei of the stria terminalis, anterior division, oval nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67257 Dorsal tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16503 posteroventral (inferior) parietal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.953184 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7839-01A-11R-2139-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NFYB-21822215-K562-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me3_Duodenum Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE102505_6_v_3_tunicamycin_human RummaGEO Drug Perturbation Signatures 1.0 null Field CA3, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24391 intermediate stratum of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46969 H3K9ac_heart_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null PANC 02.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.16484 SHP77 CCLE Cell Line Gene CNV Profiles -1.0 -1.32367 GSE125014_6_v_2_enzalutamide_human RummaGEO Drug Perturbation Signatures -1.0 null D283MED DepMap CRISPR Gene Dependency 1.0 2.76922 496100496_FWM_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.55103 GTEX-X4XX-0926-SM-46MV7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.897787 PKNOX1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03028 GCN1L1 Pathway Commons Protein-Protein Interactions 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE112761,GSE112767_1_v_5_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null anterior pretectal nucleus, ventral superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28261 POLR2A_GM12892_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE144231_4_v_1_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-103a-3p MiRTarBase microRNA Targets 1.0 null GATA2 ENCODE Transcription Factor Targets 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JUN-26020271-SMOOTH-MUSCLE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Piriform-amygdalar area, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.36977 Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RO-3306 LINCS KinomeScan Kinase Inhibitor Targets 1.0 1.23916 ATF3_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.556 GTEX-P78B-0526-SM-2I5F7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.883948 Gustatory areas, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08022 TAF1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE214823,GSE214824_5_v_7_crtc2_mouse RummaGEO Gene Perturbation Signatures -1.0 null male reproductive gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PANC0813 CCLE Cell Line Gene Mutation Profiles 1.0 null PMC12318984-Table1.xlsx-S7-Table_S7_Instrumental_variables_IVs_identified_from_eQTL_dataset_for_druggable_GIKs_used_in_Mendelian_randomization_MR_analysis_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_GM12865_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H2AFZ_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-SJXC-0726-SM-2XCFJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.34624 Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NIP7 Pathway Commons Protein-Protein Interactions 1.0 null H3K27me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null NCI-H1573 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82222 SF268 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.58139 H3K9ac_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE157894_1_v_0_cystine_human RummaGEO Drug Perturbation Signatures -1.0 null ZNF384_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WHSE-0006-SM-3NMBW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.16397 RPS25 Pathway Commons Protein-Protein Interactions 1.0 null MYCBP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.09554 AB-84-PK04_0.1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.218132 anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.33873 CAPAN2 CCLE Cell Line Gene CNV Profiles 1.0 1.76822 Diabetes Mellitus, Type 2 HuGE Navigator Gene-Phenotype Associations 1.0 null H3K27me3_Rectal Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CEBPB ENCODE Transcription Factor Targets 1.0 null PMC9013128-NIHMS1795992-supplement-4.xlsx-SKmel147_ARID2_KO_Downregulated-Gene_name_ARID2 Rummagene Transcription Factor Associations 2026 1.0 null HUNS1 CCLE Cell Line Gene Expression Profiles 1.0 1.78743 Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E8-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors -1.0 null PMC11131031-pwad060_suppl_supplementary_tables_s3.xlsx-FOXO1-knockout_bulk_RNA-seq-Differentially_expressed_genes_identified_in_bulk_RNA-seq_of_FOXO1-_-_vs_FOXO1_hMSCs_FOXO1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-P4QS-2126-SM-3NMCF GTEx Tissue Sample Gene Expression Profiles 1.0 1.51145 A549_Thalidomide_1µM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0129104 telencephalic vesicle Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06978 GTEX-OIZG-0008-SM-4E3J2 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.878428 H3K27me3_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null VZ in subcallosal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26824 GSE214931_4_v_0_temozolomide_human RummaGEO Drug Perturbation Signatures -1.0 null H3K9ac_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ZNF143 ENCODE Transcription Factor Targets 1.0 null CI1 CCLE Cell Line Gene Expression Profiles 1.0 1.70776 H3K4me3_Penis Foreskin Keratinocyte Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE235066_7_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null DSP Pathway Commons Protein-Protein Interactions 1.0 null PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_25_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null skin HPA Tissue Gene Expression Profiles -1.0 -1.12778 GTEX-OOBJ-2626-SM-2I3F6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.04942 CTCF_GM12866_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COV318 CCLE Cell Line Gene CNV Profiles -1.0 -1.46887 PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PBX3_PBX3 Rummagene Transcription Factor Associations 2026 1.0 null layer 1 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42951 Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5546-01A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.971815 PMC4060771-170289.f1.pdf-336-IRX4_IRX4 Rummagene Transcription Factor Associations 2026 1.0 null MYH9 Pathway Commons Protein-Protein Interactions 1.0 null Small cell lung carcinoma GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.61549 male reproductive system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 GTEX-RWS6-1926-SM-47JXY GTEx Tissue Sample Gene Expression Profiles -1.0 -1.24258 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.058929 SAP30 ENCODE Transcription Factor Targets 1.0 null H3K4me1_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null K562 Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -0.867335 cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.96326 GSE175787_11_v_2_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null 496100392_HIP_dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.13468 GTEX-U8XE-0826-SM-4E3J1 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.15534 an3ca HPA Cell Line Gene Expression Profiles -1.0 -0.969415 hsa-miR-320e TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 Body mass index x sex x age interaction (4df test) GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.02218 MDAMB415 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.606493 USP15 Pathway Commons Protein-Protein Interactions 1.0 null fat_a.V1 HPA Tissue Sample Gene Expression Profiles -1.0 -1.05952 nucleus LOCATE Predicted Protein Localization Annotations 1.0 null FLNB Pathway Commons Protein-Protein Interactions 1.0 null MHHES1 CCLE Cell Line Gene Expression Profiles -1.0 -2.04878 ELK4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07764 GSE178714_1_v_2_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null CTSK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03232 non-membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.045974 GTEX-S341-0006-SM-3NM8D GTEx Tissue Sample Gene Expression Profiles -1.0 -1.1464 KDM4A ENCODE Transcription Factor Targets 1.0 null GSE218060_5_v_6_decitabine_human RummaGEO Drug Perturbation Signatures -1.0 null RPS19 Pathway Commons Protein-Protein Interactions 1.0 null NCOR-22424771-293T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE210655_3_v_0_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.24974 TUBA1B Pathway Commons Protein-Protein Interactions 1.0 null EBF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 49.7236 Neuroectodermal tumor cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.002 periventricular stratum of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10921 cerebellar cortex_35 pcw_F_12295 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.5467 NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.47269 H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2995-03A-01T-0735-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TP63-23658742-EP156T-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 KLF2_02_29 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.0 NCIH661 CCLE Cell Line Gene Mutation Profiles 1.0 null GALNT12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17121 Body Mass Index DisGeNET Gene-Phenotype Associations 1.0 null Basolateral amygdalar nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.7286 A549_Givinostat_1µM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0146243 GTEX-T2IS-0926-SM-4DM5B GTEx Tissue Sample Gene Expression Profiles 1.0 0.842727 Gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 AMOTL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06837 MOLP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.908463 protein phosphorylation GO Biological Process Annotations 2025 1.0 null H3K27me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE175787_5_v_6_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_fibroblast of lung_hg19_7 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_Caco-2_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null RBBP7 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_LNCaP clone FGC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null SYNCRIP Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_brain microvascular endothelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null AKT1_OE_GDS2308[_473_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H3K4me1_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null ZBTB20_Deficiency_GDS3718_517_mouse_Developing hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE96777,GSE96778_1_v_0_zbtb4_human RummaGEO Gene Perturbation Signatures 1.0 null Breast disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.391 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.930584 RPL8 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OXRL-2626-SM-2I3F1 GTEx Tissue Sample Gene Expression Profiles 1.0 0.963321 PMC3875676__F4 PFOCR Pathway Figure Associations 2023 1.0 null TP63-23658742-EP156T-HUMAN ChEA Transcription Factor Targets 2022 1.0 null BHY Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.66612 JcP contribution to LTL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51574 PDHB Pathway Commons Protein-Protein Interactions 1.0 null GSE158834_2_v_9_palm_human RummaGEO Gene Perturbation Signatures 1.0 null Acrosomal matrix COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.555 GTEX-OOBJ-1826-SM-3NB1C GTEx Tissue Sample Gene Expression Profiles -1.0 -1.4277 primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.918314 GSE239688_4_v_0_canagliflozin_human RummaGEO Drug Perturbation Signatures -1.0 null GTEX-XUW1-0926-SM-4BONX GTEx Tissue Sample Gene Expression Profiles -1.0 -1.00864 FOXF2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16804 SARS-ddORF6_72Hour_23935999_GSE47961 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.70277 SF3A1 Pathway Commons Protein-Protein Interactions 1.0 null NCI-H1435 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-R53T-0326-SM-48FEC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.61327 GSE173810_0_v_3_igf2_mouse RummaGEO Gene Perturbation Signatures -1.0 null CDX2 ChEA Transcription Factor Targets 1.0 null spermatid development GO Biological Process Annotations 2025 1.0 null CP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.840663 Asthma HuGE Navigator Gene-Phenotype Associations 1.0 null GTEX-R3RS-0005-SM-3GAEH GTEx Tissue Sample Gene Expression Profiles -1.0 -0.922065 CCT2 Pathway Commons Protein-Protein Interactions 1.0 null Sperm flagellum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.661 PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-228-ZNF214_ZNF214 Rummagene Transcription Factor Associations 2026 1.0 null connective tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055409 H3K4me3_CD34 Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PRKAA2 Pathway Commons Protein-Protein Interactions 1.0 null PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_2_AR Rummagene Transcription Factor Associations 2026 1.0 null POLR2AphosphoS2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_Brain Anterior Caudate Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-RN64-0626-SM-2TC5V GTEx Tissue Sample Gene Expression Profiles 1.0 0.969169 Perihypoglossal nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.20807 USF1_K562_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE158834_7_v_8_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null viscus TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Colorectal cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.632 trachea BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.23083 oral mucosa HPA Tissue Protein Expression Profiles 1.0 0.857749 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.54663 fallopian tube HPA Tissue Gene Expression Profiles 1.0 1.69798 Pancreatic Carcinoma DisGeNET Gene-Disease Associations 1.0 null PMC3579516__F7 PFOCR Pathway Figure Associations 2024 1.0 null cell part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 H3K4me3_Jurkat_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Immune system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.184 mantle zone of JcPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47007 CHP-212 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.56879 MYCN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.637 Infertility, Female CTD Gene-Disease Associations 1.0 1.4076 Gli1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 27.4252 GTEX-S3XE-0006-SM-3K2AA GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 GTEX-WHSE-0011-R5A-SM-3P5ZO GTEx Tissue Sample Gene Expression Profiles 1.0 0.952932 RAD50 Pathway Commons Protein-Protein Interactions 1.0 null Cortical amygdalar area, posterior part, lateral zone, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.5034 hsa-miR-454 TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 abdominal adipose tissue TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.374618 Pharynx cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.0 organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041995 GTEX-U8XE-1226-SM-4E3HN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.69281 amygdaloid complex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.02291 USF1 JASPAR Predicted Transcription Factor Targets 1.0 null GSE149035_2_v_5_hepacam_human RummaGEO Gene Perturbation Signatures 1.0 null GSE116354,GSE117379_2_v_4_cox2_mouse RummaGEO Gene Perturbation Signatures 1.0 null TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA ChEA Transcription Factor Targets 2022 1.0 null JUND_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE175787_5_v_0_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null GSE126621,GSE126920_1_v_0_dppa4_mouse RummaGEO Gene Perturbation Signatures -1.0 null Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE216043_10_v_9_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null H3K79me1_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_myotube_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36124 HTATSF1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-R55F-1426-SM-2TF53 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.885029 inner CP in ventromedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06612 GTEX-WHSE-0011-R4A-SM-3P5ZN GTEx Tissue Sample Gene Expression Profiles 1.0 0.944625 GTEX-OXRL-0005-SM-3LK6A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.33295 GSE158834_7_v_13_palm_human RummaGEO Gene Perturbation Signatures 1.0 null GSE88819_0_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null overexpression GeneRIF Biological Term Annotations 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5465-11A-01R-1503-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null binding GO Molecular Function Annotations 2015 1.0 null Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8530322-pone.0258316.s002.xlsx-GG_776_TH17-AA_776_TH17-Symbol_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null periventricular stratum of the VAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28155 hsa-miR-1913 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 HLFA CCLE Cell Line Gene Mutation Profiles 1.0 null CDX2-19796622-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null GTEX-XXEK-0005-SM-4BRWJ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08561 GSE158834_7_v_9_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null hel HPA Cell Line Gene Expression Profiles -1.0 -0.969415 HES7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.012 G96 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06441 MAX_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.892559 secondary prosencephalon Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07762 Kdm1a_KD_GDS5055_275_mouse_3T3-L1 preadipocytes - 48h GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null COV318 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.16201 POLR2A_GM12891_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null adrenal gland HPA Tissue Protein Expression Profiles 1.0 0.857749 AIMP1 Pathway Commons Protein-Protein Interactions 1.0 null hsa-miR-520g TargetScan Predicted Conserved microRNA Targets 1.0 0.474009 GSE135350_3_v_6_dexamethasone_human RummaGEO Drug Perturbation Signatures 1.0 null GSE168587,GSE168752_3_v_1_tp53_human RummaGEO Gene Perturbation Signatures 1.0 null CAPAN-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.51367 GSK3A Pathway Commons Protein-Protein Interactions 1.0 null GTEX-N7MT-0007-SM-3GACQ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.57643 Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMC3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 496100385_TCx_dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.24481 PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WFON-2126-SM-3LK7O GTEx Tissue Sample Gene Expression Profiles -1.0 -0.84768 GSE175787_8_v_10_rhoc_human RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_skeletal muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-O2-A52S-01A-11R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT1-17558387-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null RARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.087 abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 1.09212 GTEX-U8XE-0226-SM-4E3J3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.930343 SNAI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.1243 H3K4me1_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_A549_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null HCC1500 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.984984 KRT5 Pathway Commons Protein-Protein Interactions 1.0 null abdomen TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.095955 PABPC4 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3328-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE216043_11_v_6_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null NCIH929 CCLE Cell Line Gene Expression Profiles 1.0 1.53515 GSE178714_3_v_2_smad2_human RummaGEO Gene Perturbation Signatures 1.0 null BX795_NGP LINCS Kinativ Kinase Inhibitor Bioactivity Profiles -1.0 -0.65935 HCC33 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.992869 hsa-miR-519a TargetScan Predicted Conserved microRNA Targets 1.0 0.37496 Gastrointestinal tract TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K4me3_HCT116_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE112761,GSE112767_4_v_3_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null placenta_6a HPA Tissue Sample Gene Expression Profiles -1.0 -1.01131 Lung squamous cell carcinoma_LUSC_TCGA-85-A510-01A-11R-A26W-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.14554 SIN3A_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE48812_2_v_6_sulforaphane_human RummaGEO Drug Perturbation Signatures -1.0 null TCF4-22108803-LS180-HUMAN ChEA Transcription Factor Targets 2022 1.0 null H3K4me1_thymus_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null alitretinoin_homo sapiens_gpl6480_gse43090 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null MAX_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_small intestine_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null DHX15 Pathway Commons Protein-Protein Interactions 1.0 null posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.854698 NONO Pathway Commons Protein-Protein Interactions 1.0 null intracellular part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 GSE242199_6_v_7_ntrk2_human RummaGEO Gene Perturbation Signatures 1.0 null MAX_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-VJWN-0005-SM-3GIKF GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 cohorts GeneRIF Biological Term Annotations 1.0 null GSE210885_5_v_7_klf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null periventricular stratum of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37113 GTEX-X585-0005-SM-46MV3 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.975957 forebrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.060487 pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29702 brownfat BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.868511 type 2 diabetes GAD Gene-Disease Associations 1.0 null kinase activity GO Molecular Function Annotations 2015 1.0 null Carcinoma Of Lung DisGeNET Gene-Disease Associations 1.0 null H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K4me3_keratinocyte_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null MAX_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-W5X1-0426-SM-3GILB GTEx Tissue Sample Gene Expression Profiles 1.0 1.04595 PMC6520398-41467_2019_10148_MOESM11_ESM.xls-FigS1a-TP53_TP53 Rummagene Transcription Factor Associations 2026 1.0 null Heart Defects, Congenital CTD Gene-Disease Associations 1.0 1.11186 Retrosplenial area, ventral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20251 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null dominant GeneRIF Biological Term Annotations 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.02011 occipital pole, left, lateral aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.20076 hsa-miR-4295 TargetScan Predicted Conserved microRNA Targets 1.0 0.997906 hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.19455 gastrointestinal tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.063669 Gonadal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.027 doxorubicin_homo sapiens_gpl6947_gse25741 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Medial habenula Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.14344 RPS4X Pathway Commons Protein-Protein Interactions 1.0 null outer CP in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.865493 Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EF-01A-12R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ribonucleotide binding GO Molecular Function Annotations 2015 1.0 null EML3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36881 SUB1 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-V955-2626-SM-3NM9F GTEx Tissue Sample Gene Expression Profiles -1.0 -1.71657 KRT9 Pathway Commons Protein-Protein Interactions 1.0 null GSE210580_0_v_12_rag2_mouse RummaGEO Gene Perturbation Signatures -1.0 null intracellular organelle LOCATE Predicted Protein Localization Annotations 1.0 null GSE199541_2_v_4_mbd2_mouse RummaGEO Gene Perturbation Signatures -1.0 null GSE196699_2_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null Central nervous system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.272 POLR2AphosphoS5_HepG2_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null TEAD4 ENCODE Transcription Factor Targets 1.0 null GATA2_SH-SY5Y_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Transforming growth factor beta activated kinase 1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.101 A549_Tucidinostat_10µM_72h Sci-Plex Drug Perturbation Signatures 1.0 0.0135105 Peripheral nervous system neoplasm DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.905 GSE127790_4_v_3_zcchc8_mouse RummaGEO Gene Perturbation Signatures 1.0 null ACOT8 Pathway Commons Protein-Protein Interactions 1.0 null SNRPD2 Pathway Commons Protein-Protein Interactions 1.0 null primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.38515 cardiovascular system disease GWASdb SNP-Disease Associations 1.0 0.057182 testis_7e HPA Tissue Sample Gene Expression Profiles 1.0 1.23607 GSE112761,GSE112767_2_v_0_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null RNH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03363 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPL13A Pathway Commons Protein-Protein Interactions 1.0 null STS-0421 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-XXEK-0726-SM-4BRWF GTEx Tissue Sample Gene Expression Profiles -1.0 -1.147 GTEX-OXRK-0006-SM-2HML1 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.860432 PMC9270251-mmc2.xlsx-2_Filtered_DEGs_Control_vs_KD_2-Gene_ID_AR Rummagene Transcription Factor Associations 2026 1.0 null laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.23601 GTEX-OIZG-0226-SM-2TC5L GTEx Tissue Sample Gene Expression Profiles 1.0 0.926094 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF Rummagene Transcription Factor Associations 2026 1.0 null H2AFZ_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27me3_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QESD-1526-SM-2S1QT GTEx Tissue Sample Gene Expression Profiles -1.0 -1.12253 HKE-3 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.341 CP466722 LINCS KinomeScan Kinase Inhibitor Targets 1.0 0.967615 Lung squamous cell carcinoma_LUSC_TCGA-56-7730-01A-11R-2125-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Pars tuberalis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.852 H3K4me3_skeletal muscle myoblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Thyroid gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 HNRNPA3 Pathway Commons Protein-Protein Interactions 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7R3-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE102505_1_v_2_tunicamycin_human RummaGEO Drug Perturbation Signatures 1.0 null MET_knockout_251_GDS3148 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.44986 SNU626 DepMap CRISPR Gene Dependency 1.0 2.7449 Brain Lower Grade Glioma_LGG_TCGA-FG-A4MX-01A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE147613_1_v_2_cisplatin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Viscus TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 H3K27ac_Panc1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KNS81 CCLE Cell Line Gene CNV Profiles -1.0 -1.39743 GTEX-R53T-0526-SM-3GADL GTEx Tissue Sample Gene Expression Profiles 1.0 1.01975 RPS6KA4 Pathway Commons Protein-Protein Interactions 1.0 null TCF12_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.07302 Human - Fetal Development - L1 - Ciliated epithelial cells HuBMAP Azimuth Cell Type Annotations 1.0 null striatum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03833 CLTC Pathway Commons Protein-Protein Interactions 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Disease DISEASES Experimental Gene-Disease Association Evidence Scores 2025 1.0 1.905 Sarcoma_SARC_TCGA-KD-A5QT-01A-11R-A27Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-T6MN-0626-SM-32PM9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.04272 CGP74514A LINCS KinomeScan Kinase Inhibitor Targets 1.0 1.04543 Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-U8XE-0126-SM-4E3I3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.50984 RFX5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2 Rummagene Transcription Factor Associations 2026 1.0 null isthmic part of the intermediate lateral lemniscal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00086 hsa-miR-16 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 KRT15 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_GM06990_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE138841_0_v_1_trim6_human RummaGEO Gene Perturbation Signatures -1.0 null MAPK8 Pathway Commons Protein-Protein Interactions 1.0 null Inner dynein arm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.347 H3K4me3_HL-60_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XQ8I-0426-SM-4BOPO GTEx Tissue Sample Gene Expression Profiles -1.0 -0.907968 GOS3 CCLE Cell Line Gene Expression Profiles 1.0 1.49874 PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG Rummagene Transcription Factor Associations 2026 1.0 null ITGB4 Pathway Commons Protein-Protein Interactions 1.0 null cognitive disorder GWASdb SNP-Disease Associations 1.0 0.103307 RPS13 Pathway Commons Protein-Protein Interactions 1.0 null Adult_Liver Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.28365 PMC10679662-mmc3.xlsx-NC-D5-ZEB2-Mutant-Downregulated-Gene_Symbol_ZEB2 Rummagene Transcription Factor Associations 2026 1.0 null IKBKE Pathway Commons Protein-Protein Interactions 1.0 null SNAI3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.9537 Lymphatic system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.184 GTEX-QDVJ-0626-SM-48U1T GTEx Tissue Sample Gene Expression Profiles -1.0 -0.855671 Mesothelioma_MESO_TCGA-LK-A4NY-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Supplemental somatosensory area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10146 H3K18ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27ac_Brain Hippocampus Middle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-RWS6-1026-SM-47JXD GTEx Tissue Sample Gene Expression Profiles 1.0 0.9022 CORL88 CCLE Cell Line Gene Expression Profiles 1.0 1.61268 KRT19 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-V955-0005-SM-3P5ZC GTEx Tissue Sample Gene Expression Profiles -1.0 -1.03169 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPL24 Pathway Commons Protein-Protein Interactions 1.0 null medial habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.60206 Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9RF-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null cytoplasm COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 hsa-miR-877-3p MiRTarBase microRNA Targets 1.0 null H3K4me3_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null LNCAP Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles 1.0 null Retrosplenial area, lateral agranular part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40481 primary visual cortex (striate cortex, area V1/17)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.887406 GSE175787_11_v_0_rhoc_human RummaGEO Gene Perturbation Signatures -1.0 null KATO III Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.27176 TNK1 Pathway Commons Protein-Protein Interactions 1.0 null medial ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.88208 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null outer CP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.09138 GTEX-QESD-1426-SM-2S1R9 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.04115 intermediate stratum of m1Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.28282 SUM 52PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.74211 TET1 ChEA Transcription Factor Targets 1.0 null FOXO1::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9926 TK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.896129 PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF Rummagene Transcription Factor Associations 2026 1.0 null animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05547 GSE65617_5_v_3_aire_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K9ac_GM12878_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Lung cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.794 GSE196104,GSE196106_3_v_1_vsx2_mouse RummaGEO Gene Perturbation Signatures -1.0 null HIST1H1A Pathway Commons Protein-Protein Interactions 1.0 null GSE225869_2_v_0_temozolomide_human RummaGEO Drug Perturbation Signatures 1.0 null ZEB1 ENCODE Transcription Factor Targets 1.0 null lateral pallium Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22883 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A7UZ-01A-12R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_cardiac muscle cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Sarcoma_SARC_TCGA-HB-A3L4-01A-11R-A21T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GD-66-XE49_10uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.207133 LS411N CCLE Cell Line Gene Mutation Profiles 1.0 null premotor cortex (area 6) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.06719 H3K4me3_foreskin fibroblast_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null DSG1 Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-90-A4EE-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE112761,GSE112767_2_v_5_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null CTCF_GM12870_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dms153 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.473 PMC4266008-mmc3.xlsx-iPS-MSC_vs_MSC-Unnamed_1_MSC Rummagene Transcription Factor Associations 2026 1.0 null Rectum adenocarcinoma_READ_TCGA-CI-6621-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-503 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 hsa-miR-195 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 GSE144231_4_v_7_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null HES2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6968 H3K56ac_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null OlfactoryBulb BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.920355 GTEX-RWSA-0926-SM-47JXW GTEx Tissue Sample Gene Expression Profiles -1.0 -1.45702 Vagina TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 H3K4me1_G1E-ER4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null LNCAP-CLONE-FGC COSMIC Cell Line Gene Mutation Profiles 1.0 null RB1_KD_GSE50532_660_human_OSTEOBLASTS GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-7315-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null STAT3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Basomedial amygdalar nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21999 496100462_PCx_dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.40662 Smoking Behaviors DisGeNET Gene-Phenotype Associations 1.0 null PRKDC Pathway Commons Protein-Protein Interactions 1.0 null G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14567 H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null POLR2AphosphoS5_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null MVP Pathway Commons Protein-Protein Interactions 1.0 null PSMC6 Pathway Commons Protein-Protein Interactions 1.0 null PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null median eminence TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.537812 MYB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.905 central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.078107 H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null 496100480_HIP_no dementia_TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.61401 protein serine/threonine kinase activity GO Molecular Function Annotations 2023 1.0 null UTRN Pathway Commons Protein-Protein Interactions 1.0 null NCIN87 CCLE Cell Line Gene CNV Profiles -1.0 -1.4369 HSP90AB1 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Mucosa TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 ILF2_02_70 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.39232 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MC-06A-12R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null respiratory epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.079662 hsa-miR-520h TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 hsa-miR-1257 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 RAD21 ENCODE Transcription Factor Targets 1.0 null hsa-miR-219-1-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 Oviduct TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 r7 part of nucleus prepositus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.89876 Kidney renal papillary cell carcinoma_KIRP_TCGA-B1-A47N-01A-11R-A24Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.824455 KMRC2 CCLE Cell Line Gene Mutation Profiles 1.0 null body mass index GAD Gene-Disease Associations 1.0 null olfactory part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.997735 GTEX-T2IS-2026-SM-4DM6W GTEx Tissue Sample Gene Expression Profiles 1.0 0.941574 GSE245418_0_v_2_cd109_human RummaGEO Gene Perturbation Signatures -1.0 null Perturb_8957_OE_MYCN_SRP223240 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 7.27371 GSE193541_0_v_3_nifurtimox_human RummaGEO Drug Perturbation Signatures -1.0 null superficial stratum of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25707 Obesity DisGeNET Gene-Disease Associations 1.0 null ESRRG_Deficiency_GDS2811_637_mouse_Fetal heart - Heterozygous null mutant GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null POLR2A_H54_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null dorsolateral prefrontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.887916 GTEX-XK95-1026-SM-4GIDV GTEx Tissue Sample Gene Expression Profiles -1.0 -0.91543 SRF_KO_GDS3732_148_mouse_HSC GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null MAX_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null MYBL1_KO_GDS4485_349_mouse_Testis from 14 day old GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PMC10550934-41467_2023_41927_MOESM4_ESM.xlsx-degenes_beatAML_CEBPA-NT_Fig1c-Gene_Symbol_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null cytoplasmic part COMPARTMENTS Experimental Protein Localization Evidence Scores 1.0 0.233497 chr11_8476681_C_A_b38 GTEx eQTL 2025 1.0 2.43599 H3K4me2_Muscle Satellite Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX4_SOX4 Rummagene Transcription Factor Associations 2026 1.0 null GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null H2AFZ_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1_A549_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null ELF1_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_cardiac mesoderm_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cellular component assembly GO Biological Process Annotations 2025 1.0 null medial ganglionic eminence_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.64966 urogenital system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null ventricular (matrix) zone of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.74198 RAD21_CH12.LX_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2919-03A-01T-0740-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null protein phosphorylation GO Biological Process Annotations 2023 1.0 null SNU-638 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36433 GTEX-NPJ8-1826-SM-2YUNC GTEx Tissue Sample Gene Expression Profiles -1.0 -0.842207 GSE126345_4_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE239844_6_v_0_crizotinib_human RummaGEO Drug Perturbation Signatures -1.0 null PMC5557398-13045_2017_515_MOESM1_ESM.xlsx-S12-ZNF384_DiffExprGene-Unnamed_1_ZNF384 Rummagene Transcription Factor Associations 2026 1.0 null GSE248883_0_v_1_shmt2_mouse RummaGEO Gene Perturbation Signatures -1.0 null protein metabolic process GO Biological Process Annotations 2015 1.0 null Lung adenocarcinoma_LUAD_TCGA-49-6742-11A-01R-1858-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84B-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7MC-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null alveolar macrophage TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.361155 Piriform-amygdalar area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.71148 PML ENCODE Transcription Factor Targets 1.0 null mRNA_ASCL1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-PLZ5-1526-SM-3P5ZX GTEx Tissue Sample Gene Expression Profiles 1.0 1.32416 GSE205070_2_v_5_mertk_mouse RummaGEO Gene Perturbation Signatures -1.0 null EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE126345_9_v_3_hcrt_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-SJXC-1226-SM-4DM78 GTEx Tissue Sample Gene Expression Profiles -1.0 -0.970702 capan2 HPA Cell Line Gene Expression Profiles -1.0 -0.969415 DHX9 Pathway Commons Protein-Protein Interactions 1.0 null NUP58 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13487 H3K4me3_CD8 Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ARID3A_02_50 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.85798 EBF1_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null HIST1H4F Pathway Commons Protein-Protein Interactions 1.0 null subbrachial nucleus, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.64967 GTEX-X4XX-0005-SM-3NMCS GTEx Tissue Sample Gene Expression Profiles -1.0 -1.29015 CAL-62 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.658 GTEX-V955-0426-SM-3GAEL GTEx Tissue Sample Gene Expression Profiles 1.0 1.02788 Breast - Mammary Tissue GTEx Tissue Gene Expression Profiles 2023 1.0 3.54736 primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.10857 Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TET1-21490601-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null periventricular stratum of ITTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09652 H3K4me1_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null atherosclerosis GWASdb SNP-Phenotype Associations 1.0 0.29639 Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-A8LB-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-QH-A870-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null blast cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.066469 ZNF682 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.1371 GTEX-REY6-0326-SM-2TF5A GTEx Tissue Sample Gene Expression Profiles -1.0 -1.6458 GSE158834_2_v_9_palmitic acid_human RummaGEO Drug Perturbation Signatures 1.0 null H3K4me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Tal-1beta:ITF-2 MotifMap Predicted Transcription Factor Targets 1.0 null GSE123502,GSE123504_1_v_0_chd4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE205070_2_v_7_mertk_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5549-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE196699_0_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-OXRP-2426-SM-2S1NR GTEx Tissue Sample Gene Expression Profiles -1.0 -0.965818 EGR1-20690147-ERYTHROLEUKEMIA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.042202 mRNA_ID1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PMC7334247-12031_2020_1490_MOESM2_ESM.xls-THAP1_S21T_vs_wt-Gene_Symbol_THAP1 Rummagene Transcription Factor Associations 2026 1.0 null SMMC-7721 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.728 USF2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null A549_Abexinostat_10µM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0096799 hsa-miR-20b TargetScan Predicted Conserved microRNA Targets 1.0 0.49473 H3K4me1_CD34 Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lower respiratory tract disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.684 PMC9314667-Table_1.xlsx-Regulons-FOSL1_FOSL1 Rummagene Transcription Factor Associations 2026 1.0 null liminal alar domain of m2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41543 H3K27ac_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null AR-19668381-PC3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null POLR2A_GM19193_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null USF1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CTCF_GM12873_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null DNA damage checkpoint signaling GO Biological Process Annotations 2025 1.0 null GTEX-P4PQ-2626-SM-33HC9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.27994 A549_Nintedanib_10µM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0113651 A-427 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.034 Yy1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.3908 DLAT Pathway Commons Protein-Protein Interactions 1.0 null nucleoside phosphate binding GO Molecular Function Annotations 2015 1.0 null GSE226249_2_v_1_pirfenidone_human RummaGEO Drug Perturbation Signatures -1.0 null GSE151412_2_v_1_sorafenib_human RummaGEO Drug Perturbation Signatures -1.0 null GSE142210_2_v_7_panobinostat_human RummaGEO Drug Perturbation Signatures 1.0 null calciumcalmodulin GeneRIF Biological Term Annotations 1.0 null PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA4_GATA4 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Basomedial amygdalar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.15019 BHLHE40 ENCODE Transcription Factor Targets 1.0 null GTEX-WL46-0526-SM-3LK7W GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21277 NFYA JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-R55E-0726-SM-48FCZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.93861 18277965-Table4b GeneSigDB Published Gene Signatures 1.0 null GSE169263_1_v_0_armc5_mouse RummaGEO Gene Perturbation Signatures 1.0 null RPS24 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-Q2AH-1526-SM-48TZG GTEx Tissue Sample Gene Expression Profiles 1.0 1.68868 GSE202434,GSE202438_12_v_5_talazoparib_human RummaGEO Drug Perturbation Signatures 1.0 null orbital frontal cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.60885 Pancreatic Neoplasm DisGeNET Gene-Disease Associations 1.0 null H3K9ac_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null USF2_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_GM12875_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Uterus TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 HSP90-CDC37 chaperone complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.654 NCI-H187 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.06441 hsa-miR-4667-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 occipital neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.849707 STAT3 ENCODE Transcription Factor Targets 1.0 null GTEX-VUSG-0626-SM-4KL1Z GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 YH13 CCLE Cell Line Gene CNV Profiles -1.0 -1.62178 AP1M1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04504 GTEX-REY6-0126-SM-48FDT GTEx Tissue Sample Gene Expression Profiles 1.0 1.73045 Hypopharyngeal squamous cell carcinoma cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.049 EP300_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CHAC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.0876 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RPS3 Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-98-A53H-01A-12R-A262-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UPF 648 DeepCoverMOA Drug Mechanisms of Action 1.0 0.24 GSE145323,GSE145324_1_v_0_rfx3_mouse RummaGEO Gene Perturbation Signatures -1.0 null H4K5ac_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null protein serine/threonine kinase activity GO Molecular Function Annotations 2015 1.0 null H3K9ac_Colon Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null inner CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21499 periventricular mantle of isBM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.41103 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.15344 H3K4me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EP300_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ISYNA1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17256 Organ system cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.893 H3K4me3_megakaryocyte_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_fibroblast of gingiva_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null EGR1 ChEA Transcription Factor Targets 1.0 null Gustatory areas, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07762 Thorax TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 female reproductive gland TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 0.766457 protein autophosphorylation GO Biological Process Annotations 2015 1.0 null GTEX-RTLS-1326-SM-46MUN GTEx Tissue Sample Gene Expression Profiles -1.0 -1.23461 TUBA1C Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RAD21_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null liminal reticular formation of m2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.50178 Lymphoma_burkitts(Daudi) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.835325 Primitive neuroectodermal tumor cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.124 NCI-H661 COSMIC Cell Line Gene Mutation Profiles 1.0 null Carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.798 RPS6 Pathway Commons Protein-Protein Interactions 1.0 null TUBA4A Pathway Commons Protein-Protein Interactions 1.0 null H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC12187926-41421_2025_809_MOESM8_ESM.xlsx-w_SRPK2-KD-kinase_AR Rummagene Transcription Factor Associations 2026 1.0 null macromolecule metabolic process GO Biological Process Annotations 2015 1.0 null phosphate-containing compound metabolic process GO Biological Process Annotations 2015 1.0 null Small Cell Carcinoma Of Lung DisGeNET Gene-Disease Associations 1.0 null HES5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0707 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null neurohypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.43989 GTEX-XAJ8-0006-SM-46MVM GTEx Tissue Sample Gene Expression Profiles -1.0 -1.18178 H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null GSE158834_11_v_8_palmitic acid_human RummaGEO Drug Perturbation Signatures -1.0 null KRT8 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-OOBJ-2126-SM-3NB1N GTEx Tissue Sample Gene Expression Profiles 1.0 1.65965 PMC12827430-41467_2025_67591_MOESM6_ESM.xlsx-Figure_4f-FOSL2_ChIP_WT-exclusive_genes_FOSL2 Rummagene Transcription Factor Associations 2026 1.0 null liver_c HPA Tissue Sample Gene Expression Profiles -1.0 -2.07549 GTEX-R53T-2026-SM-3GIJF GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 adenyl ribonucleotide binding GO Molecular Function Annotations 2015 1.0 null TCF3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Primary ciliary dyskinesia 13 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.522 GSE180813,GSE180815_1_v_0_mettl3_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perinuclear theca COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.555 GSE185163_3_v_1_clic4_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WEY5-0006-SM-3GIKG GTEx Tissue Sample Gene Expression Profiles -1.0 -1.08786 dorsal spiriform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60192 H3K4me3_cardiac fibroblast_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XLM4-0011-R8A-SM-4AT44 GTEx Tissue Sample Gene Expression Profiles 1.0 0.952949 Breast_Myoepithelial_Cells Roadmap Epigenomics Cell and Tissue Gene Expression Profiles -1.0 -1.99249 H3K4me3_HeLa-S3_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 VPS33A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43049 CCDC134 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.91011 Plasma membrane bounded cell projection cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.298 GTEX-R45C-0006-SM-3GAD6 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.57353 GSE112765,GSE112767_1_v_0_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-Q2AH-0005-SM-33HBR GTEx Tissue Sample Gene Expression Profiles -1.0 -1.62989 RPS27 Pathway Commons Protein-Protein Interactions 1.0 null H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-4675 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 PAX3_01_359 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.76189 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.223165 Protein kinase-like domain InterPro Predicted Protein Domain Annotations 1.0 null GSE86507,GSE86509_3_v_8_hoxb7_mouse RummaGEO Gene Perturbation Signatures 1.0 null ETS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3866 H3K4me3_mammary epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null H3K4me3_endothelial cell of umbilical vein_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S3XE-1726-SM-3K2AM GTEx Tissue Sample Gene Expression Profiles -1.0 -0.961968 GSE216043_10_v_4_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null lung BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.07371 GTEX-XGQ4-0005-SM-4AT5U GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 intermediate stratum of LAP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.95085 posterolateral cortical amygdaloid area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57998 SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null respiratory system cancer GWASdb SNP-Disease Associations 1.0 0.361868 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF Rummagene Transcription Factor Associations 2026 1.0 null GTEX-PLZ6-0006-SM-33HBZ GTEx Tissue Sample Gene Expression Profiles -1.0 -1.53877 stomach TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80P-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null uterine cervix TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null THAP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.3347 GTEX-WH7G-0526-SM-3NMBI GTEx Tissue Sample Gene Expression Profiles 1.0 0.929723 MYC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1382 GSE142210_4_v_7_panobinostat_human RummaGEO Drug Perturbation Signatures 1.0 null GTEX-XUW1-0726-SM-4BOP5 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 survival GeneRIF Biological Term Annotations 1.0 null Piriform area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21405 GSE221386_3_v_0_romidepsin_human RummaGEO Drug Perturbation Signatures -1.0 null USF1_HCT116_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null WRNIP1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null RPL7 Pathway Commons Protein-Protein Interactions 1.0 null GSE102505_1_v_0_tunicamycin_human RummaGEO Drug Perturbation Signatures 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-01A-02R-1325-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Neuroepithelioma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.972 Stomach Carcinoma DisGeNET Gene-Disease Associations 1.0 null HCC193 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.36124 USF1_ECC-1_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null disease GWASdb SNP-Disease Associations 1.0 0.045971 Neurohypophysis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.073 plicamycin_homo sapiens_gpl570_gse25127 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null NCIH1339 CCLE Cell Line Gene Mutation Profiles 1.0 null GTEX-RWS6-0008-SM-47JYV GTEx Tissue Sample Gene Expression Profiles -1.0 -1.07756 ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null fallopian tube GTEx Tissue Gene Expression Profiles 1.0 0.86819 RPL3 Pathway Commons Protein-Protein Interactions 1.0 null GTEX-WI4N-1026-SM-3LK7N GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 GTEX-QV44-0826-SM-2S1RG GTEx Tissue Sample Gene Expression Profiles 1.0 1.22897 GSE131377_1_v_3_spocd1_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_astrocyte of the spinal cord_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null fallopiantube_8c HPA Tissue Sample Gene Expression Profiles 1.0 1.904 Integument TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 NFYB ENCODE Transcription Factor Targets 1.0 null TAL1::TCF3 MotifMap Predicted Transcription Factor Targets 1.0 null GLIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.8311 GTEX-TKQ1-0926-SM-4DXU2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.91267 medial habenular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.15897 KYO1 CCLE Cell Line Gene Mutation Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-6D-AA2E-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-20b TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 Neoplasm Metastasis DisGeNET Gene-Phenotype Associations 1.0 null DNA damage checkpoint signaling GO Biological Process Annotations 2023 1.0 null hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.897983 Rectum adenocarcinoma_READ_TCGA-AH-6903-01A-11R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3440-01A-02R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE235066_7_v_3_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null ZNF45 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.51166 rostral division of OFCi (area 11) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.82475 POLR2A_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Gastrointestinal system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.617 perinuclear region of cytoplasm GO Cellular Component Annotations 2015 1.0 null small molecule binding GO Molecular Function Annotations 2015 1.0 null downregulation GeneRIF Biological Term Annotations 1.0 null Nkx3-2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.8444 Stomach disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.055 superficial stratum of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51574 SIN3A ENCODE Transcription Factor Targets 1.0 null GTEX-X88G-0126-SM-47JZ3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.27678 SARS-CoV MA15_Day7-CXCR3KO_None_GSE50878 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.92126 Breast cancer DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.383 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CCT3 Pathway Commons Protein-Protein Interactions 1.0 null CKAP4 Pathway Commons Protein-Protein Interactions 1.0 null H3K4me2_A549_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42003 ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.846931 ELK1_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K23me2_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE112760,GSE112767_1_v_5_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null Adult body size GWAS Catalog SNP-Phenotype Associations 2025 1.0 1.3699 ventrolateral prefrontal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.847354 GTEX-XUJ4-2426-SM-4BOO3 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.47125 ZNF784 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4504 MAIP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.02735 hippocampus (hippocampal formation)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.00393 JHH6 CCLE Cell Line Gene CNV Profiles 1.0 1.73721 GTEX-RM2N-1826-SM-2TF5B GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 adenyl nucleotide binding GO Molecular Function Annotations 2015 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7860-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF30 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.09696 PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF Rummagene Transcription Factor Associations 2026 1.0 null USF1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XYKS-2126-SM-4E3IB GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 USF1_ECC-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3Z7-01A-12R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GSE199092_3_v_0_ddx5_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null EGFR Pathway Commons Protein-Protein Interactions 1.0 null GSE169356_2_v_4_ivermectin_human RummaGEO Drug Perturbation Signatures -1.0 null Liver disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.201 Myc-Max complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.723 breast GTEx Tissue Gene Expression Profiles -1.0 -0.86573 WC-16-IR43_1uM NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles -1.0 -0.202574 Hepatocellular carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.244 H3K4me3_GM12878_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.055471 medial habenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09247 JUN-27471255-CHONDROCYTES-MOUSE-RIB ChEA Transcription Factor Targets 2022 1.0 null GSE112762,GSE112767_2_v_0_dgcr8_mouse RummaGEO Gene Perturbation Signatures -1.0 null mood disorder GWASdb SNP-Disease Associations 1.0 0.307587 H2AFZ ENCODE Transcription Factor Targets 1.0 null ITPRID2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.00106 GTEX-R55G-0006-SM-2TC6O GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 PMC12297505-41598_2025_11704_MOESM4_ESM.xlsx-table_s4_veen-TCGA-GBMLGG_AND_Human_kinases_NOT_GSE16011_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null MYBBP1A Pathway Commons Protein-Protein Interactions 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-56-7582-11A-01R-2045-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-R55F-1726-SM-2TF4R GTEx Tissue Sample Gene Expression Profiles -1.0 -0.898723 GTEX-WVLH-0006-SM-3MJF7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.21087 PMC3152520-1479-5876-9-119-S2.XLS-Sheet1-STAT1_STAT1 Rummagene Transcription Factor Associations 2026 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-MI-A75I-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Sheet3-The_overlapping_genes_between_significantly_co-expressed_genes_and_significantly_differentially_expressed_genes_of_BARX2_in_LIHC_BARX2 Rummagene Transcription Factor Associations 2026 1.0 null ATF3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nkx3-1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.2301 H3K4me1_spleen_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null KDM1A_KD_GDS5055_457_mouse_adipose tissue GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null H2AFZ_B cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K4me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE142210_9_v_0_panobinostat_human RummaGEO Drug Perturbation Signatures 1.0 null MFE280 DepMap CRISPR Gene Dependency 1.0 2.04671 GTEX-WWYW-0426-SM-3NB31 GTEx Tissue Sample Gene Expression Profiles -1.0 -2.16238 MET Pathway Commons Protein-Protein Interactions 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A41B-01A-11R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Limbic system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.001 FOXJ2::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.4867 H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HNRNPU Pathway Commons Protein-Protein Interactions 1.0 null H3K4me1_Fetal Lung Roadmap Epigenomics Histone Modification Site Profiles 1.0 null had GeneRIF Biological Term Annotations 1.0 null GSE146612_1_v_0_amiodarone_human RummaGEO Drug Perturbation Signatures -1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.03591 Sperm head COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.119 GTEX-SNOS-1126-SM-4DM67 GTEx Tissue Sample Gene Expression Profiles 1.0 1.89166 ER membrane insertion complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.33 hsa-miR-4741 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 A549_G007-LK_10nM_24h Sci-Plex Drug Perturbation Signatures 1.0 0.0165289 CHD1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC9618568-41467_2022_34255_MOESM4_ESM.xlsx-TAL1-Unnamed_0_TAL1 Rummagene Transcription Factor Associations 2026 1.0 null H3K79me2_A549_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null YY1_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A7TA-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSMC1 Pathway Commons Protein-Protein Interactions 1.0 null HS-68 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.811 EEF1G Pathway Commons Protein-Protein Interactions 1.0 null inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.37261 H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null EZH2_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null upper (rostral) rhombic lip_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.934622 COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00793 GTEX-Q2AI-0006-SM-2I3FG GTEx Tissue Sample Gene Expression Profiles -1.0 -0.831026 GSE216043_11_v_2_cisplatin_human RummaGEO Drug Perturbation Signatures -1.0 null H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-S4Q7-0006-SM-3K2AT GTEx Tissue Sample Gene Expression Profiles -1.0 -0.978285 Medial pretectal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.65101 intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.041107 POLR2A_GM18951_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null EFTUD2 Pathway Commons Protein-Protein Interactions 1.0 null HEBP1 Pathway Commons Protein-Protein Interactions 1.0 null GSE216043_10_v_0_cisplatin_human RummaGEO Drug Perturbation Signatures 1.0 null H3K9ac_Peripheral Blood Mononuclear Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-QDVN-0006-SM-48U1R GTEx Tissue Sample Gene Expression Profiles -1.0 -1.55821 GTEX-WEY5-1926-SM-3GIL8 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.0906 PDK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.82919 GTEX-SJXC-0005-SM-2XCE7 GTEx Tissue Sample Gene Expression Profiles -1.0 -1.44297 NCIH889 CCLE Cell Line Gene Expression Profiles 1.0 1.67719 POLR2A ENCODE Transcription Factor Targets 1.0 null Endocrine gland TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 LIMS1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.66711 cell part LOCATE Predicted Protein Localization Annotations 1.0 null JHH5 CCLE Cell Line Gene CNV Profiles 1.0 1.69278 H3K4me3_cardiac mesoderm_hg19_8 ENCODE Histone Modification Site Profiles 1.0 null GSE160817_4_v_1_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null PMC7898758-40168_2020_994_MOESM4_ESM.xls-STAT1_target_genes-Gene_STAT1 Rummagene Transcription Factor Associations 2026 1.0 null RAI1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12813 dorsolateral prefrontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.10847 GTEX-T2IS-3126-SM-32QPK GTEx Tissue Sample Gene Expression Profiles 1.0 2.2992 Liver hepatocellular carcinoma_LIHC_TCGA-ED-A82E-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POLR2AphosphoS5_GM12891_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.07352 H3K4me3_mammary epithelial cell_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.34664 CHP212 CCLE Cell Line Gene CNV Profiles -1.0 -1.78425 Pancreatic ductal adenocarcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.231 SP4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CREB1 ENCODE Transcription Factor Targets 1.0 null H3K27me3_cardiac mesoderm_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YN-11A-11R-A10U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null inferior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.897708 TCF4-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null Lung non-small cell carcinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.661 Hippocampus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.091 GTEX-S341-0726-SM-4AD5R GTEx Tissue Sample Gene Expression Profiles 1.0 1.04712 Endopiriform nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.74874