association	dataset	threshold value	standardized value
NU-DUL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.50863
m1Lim part of the midbrain reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10502
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7301
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14129
hsa-miR-524-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
RECQL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52703
superficial stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89183
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23979
p1 portion of the paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6432
CA46	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.082
hippocampus (hippocampal formation)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.90192
ERF::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8807
CACNG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60152
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.88348
Medial pretectal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34785
SRY-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
subbrachial nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55935
ZNF347	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93872
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.914936
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
TTC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6364
Brain Lower Grade Glioma_LGG_TCGA-S9-A7R2-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TUBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49798
NSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01726
Vestibular labyrinth	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.386
PAPLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44493
A-CA-04-2009(H1N1)_48Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.996
CNIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9102
preoptic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08341
ZNF660	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34856
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.959838
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996515
ADAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93869
r3 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30365
periventricular stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15152
A-431	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.82649
Semicircular canal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
NFKBIZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55685
CENPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73286
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05219
Hair cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.457
C10orf82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82599
TUNAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52221
Spinal nucleus of the trigeminal, oral part, rostral dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.13681
testis	HPA Tissue Protein Expression Profiles	-1.0	-0.766156
GSE144443_0_v_6_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
lateral dorsal nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.18508
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8309-11A-01R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU489	CCLE Cell Line Gene Expression Profiles	-1.0	-2.52791
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
hsa-miR-4312	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
CREB1_01_195	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	3.36876
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.20026
Foramen magnum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.894
brain	GTEx Tissue Gene Expression Profiles	1.0	0.834461
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93W-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40773
hsa-miR-4639-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BLM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23343
NCIH1975	CCLE Cell Line Gene CNV Profiles	-1.0	-1.65878
TARS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38344
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE123022,GSE123030_8_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27915
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5844
VMRCRCW	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72404
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.941854
Cyclin E1-CDK2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.58
YPEL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92099
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	1.0	3.13871
Trigeminal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.303
NCI-H1688	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
A-Netherlands-602-2009(H1N1)_18Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.8983
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.101
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5461-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4592
Kidney Chromophobe_KICH_TCGA-KN-8430-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IJ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DBI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50411
Pedal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.791
ACAD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3749
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.65029
Sarcoma_SARC_TCGA-FX-A2QS-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3I3-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SNU1033	DepMap CRISPR Gene Dependency	1.0	11.6577
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.580818
PCMTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51827
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8505
Cochlear duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.448
PROX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6782
intermediate stratum of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43093
Rectum adenocarcinoma_READ_TCGA-EI-6509-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-892b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
PARPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.46968
NCIH1355	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81755
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.782
Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.974645
nucleus subputaminalis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04041
MMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28536
CSRNP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99177
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.028796
thyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-0.766156
Intrinsic component of periplasmic side of cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.755
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45528
NCIH292	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57079
SMAD4-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.1444
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17617
amplification	GeneRIF Biological Term Annotations	1.0	null
Cell envelope	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.155
SNUC1	CCLE Cell Line Gene CNV Profiles	1.0	1.78611
membrane	LOCATE Curated Protein Localization Annotations	1.0	null
lung	GTEx Tissue Gene Expression Profiles	1.0	1.04772
GIPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.29381
cell projection	GO Cellular Component Annotations 2015	1.0	null
EPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20435
PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_13_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
RRP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57832
CKLF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32368
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.1928
SMAD2/3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53996
MTA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73974
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.022
JMSU1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.78013
NUDT11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2198
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GR-ST	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
FOXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09267
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_18Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.16025
SRCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54436
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
HSF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2103
SU-DHL-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.992751
JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.3949
FOXJ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82081
EFM-19	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.36462
APLP2_KO_GDS4414_534_mouse_adult cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
LCTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49616
central nucleus of inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.911523
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67023
gliosarcoma	GeneRIF Biological Term Annotations	1.0	null
CYB5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66717
intermediate stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2008
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
USP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21003
Macrocytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.135
CCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16061
SNU213	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81694
Hemolytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.377
HOXD10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3302
RPMI8226	CCLE Cell Line Gene Expression Profiles	1.0	1.5867
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1285
NCIH929	CCLE Cell Line Gene Expression Profiles	1.0	1.77435
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050907
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61313
PAICS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19185
YWHAQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1702
CTCF-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
AMH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37957
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1681
16912175-SuppTable3b	GeneSigDB Published Gene Signatures	1.0	null
superficial stratum of CoPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17031
MZ in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43628
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
RETSAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97062
SNUPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90527
r4 part of descending trigeminal sensory nucleus, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88464
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2826
RI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.082
CAOV3	CCLE Cell Line Gene Expression Profiles	1.0	1.35181
periventricular stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07492
CLDN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20488
trachea	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-548c-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.18542
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1348
ZNF586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13583
liminal periaqueductal gray of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18427
membrane raft	GO Cellular Component Annotations 2015	1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.593
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.966541
Trigeminal neuralgia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
IRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90618
MMAC	DepMap CRISPR Gene Dependency	1.0	2.33755
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062284
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99147
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6728
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13739
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.531089
SLC38A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64104
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intermediate stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42373
r1 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03008
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.851222
MROH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79293
hsa-miR-4287	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
LRRC73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12128
ATG2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97498
Dehydrated hereditary stomatocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.313
ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6944
REEP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39916
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00694
sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.22514
FOXL1	JASPAR Predicted Transcription Factor Targets	1.0	null
CEP170	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99639
Membrane microdomain	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.734
ZNF410	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9807
ADCY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81167
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837951
Mitochondrial prohibitin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.869
Velum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.745
TCF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13271
Entorhinal area, medial part, ventral zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41346
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4741
anterior paraventricular nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62308
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837951
PPP1R37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60803
Prostate adenocarcinoma_PRAD_TCGA-HC-7231-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXD4L5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53311
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.26799
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33017
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23611
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2641
D542MG	DepMap CRISPR Gene Dependency	1.0	8.45148
EP300_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parvicellular interstitial nucleus of the posterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.73934
DROSHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90776
Insulinoma	DisGeNET Gene-Disease Associations	1.0	null
Stereocilium bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.078
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	2.111
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1816
PMC9306206-12915_2022_1367_MOESM6_ESM.xlsx-Table_S7_-_JIP-Gene_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4472	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.99791
FZD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56835
arterial stenosis	GWASdb SNP-Phenotype Associations	1.0	0.249501
LRWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58624
GUK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65334
SLC35F5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29728
NCI-H929	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.11737
MCC142	DepMap CRISPR Gene Dependency	1.0	2.85747
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.45444
FAM98C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96323
APOBEC3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2701
POLQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85922
Lung adenocarcinoma_LUAD_TCGA-97-8552-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TTC31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19004
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50016
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0757
LRR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2517
mantle zone of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24895
MINPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15663
CRK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05471
Rumen epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.777
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089076
PLSCR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32771
MSANTD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83297
SW948	CCLE Cell Line Gene CNV Profiles	1.0	2.26146
DTWD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72602
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.06485
intermediate stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26158
abnormal spinal reflex	MPO Gene-Phenotype Associations	1.0	null
CDX2-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GPR150	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60993
primary visual cortex (striate cortex, area V1/17)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.848717
Stereocilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.108
intermediate stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01276
B3GALT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22986
PRICKLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31379
GSE199644_3_v_2_palmitic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEX264	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16149
RH30	CCLE Cell Line Gene CNV Profiles	1.0	1.47966
NCIH1781	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48241
18451145-TableS1	GeneSigDB Published Gene Signatures	1.0	null
rosiglitazone_mus musculus_gpl1261_gds3798	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050344
DCUN1D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82637
EXOC3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49826
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0202
KYSE30	CCLE Cell Line Gene Expression Profiles	1.0	1.57103
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47504
TE14	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03478
PGR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65799
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63225
CAL33	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61685
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EW7	DepMap CRISPR Gene Dependency	1.0	2.03997
Side of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.125
ZNF547	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5332
hsa-miR-4633-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
ERICH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91864
GSE198054,GSE198057_0_v_1_csf1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.983612
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0087
MED13L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47573
hsa-miR-548d-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE140607_0_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Filtration diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.583
ZFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57356
posterior intralaminar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.59976
FOXM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5293
Interanterodorsal nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.95895
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2264
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94477
CSNK2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46184
icSARS CoV_36Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.2626
Nose	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.613
CCNI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58838
C12orf29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86576
Edema	CTD Gene-Disease Associations	1.0	1.0894
COLO 205	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66595
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.8456
MZ in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.926603
GNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99301
APLP2_KO_GDS4414_371_mouse_prefrontal cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
PMC5787244-13229_2018_191_MOESM1_ESM.xlsx-FOXO1_GSEA_txt-GENE_SYMBOL_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-559	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.676
WRNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02755
KATNBL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37009
Endocytic vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.586
HAPSTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53655
IZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11994
SWAP70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35813
Lung squamous cell carcinoma_LUSC_TCGA-22-4605-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.87806
Prostate adenocarcinoma_PRAD_TCGA-WW-A8ZI-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68517
BARHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22861
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gliosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.3555
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.985974
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58273
CCNJL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52566
ZBTB45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17395
SNU-C1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66595
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.15
Lung adenocarcinoma_LUAD_TCGA-49-4512-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Trigeminal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.134
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846109
CL-40	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14824
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72953
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.90554
endometrium	HPA Tissue Gene Expression Profiles	1.0	0.941499
SCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6773
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ATF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.024
RAB8B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82526
biological regulation	GO Biological Process Annotations 2015	1.0	null
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.5509
SLC1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36409
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2475
SHLD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24847
COPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16649
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Gene_Name_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50302
Fbxl10_OE_GDS4788_327_mouse_MEF fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
CR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62788
endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.097533
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3991
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.828439
A2058	CCLE Cell Line Gene Expression Profiles	-1.0	-1.76606
Lung squamous cell carcinoma_LUSC_TCGA-34-5234-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12128_KO_Dnmt3a_SRP033096	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.92282
SOX9	ChEA Transcription Factor Targets	1.0	null
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28369
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6228-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TIMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66638
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.52915
ORMDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43218
USP22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64339
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043292
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02207
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03342
hsa-miR-606	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ZNF605	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18337
Fbxl10_OE_GSE34691_579_mouse_fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE84922,GSE84924_0_v_3_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Retrocerebral complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.824
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3429-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10981
Spiral organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.459
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I0-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-588	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.82649
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.6362
RAB31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74313
SW 620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34479
OVOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42741
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.27792
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A268-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UQCR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6181
cervix uteri	GTEx Tissue Gene Expression Profiles	1.0	0.977316
DTYMK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91609
GSE174701_4_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08459
WM88	DepMap CRISPR Gene Dependency	1.0	4.91918
POU2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73155
anterior pretectal nucleus, ventral superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35885
GSE195559_6_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hypoalgesia	MPO Gene-Phenotype Associations	1.0	null
SLC7A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30726
GSE203308_15_v_10_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CIPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05607
JcPV part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09539
Olfactory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.633
hsa-miR-4760-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Pilus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.16
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82124
PMC4872452__F2	PFOCR Pathway Figure Associations 2024	1.0	null
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SW403	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.1293
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MOCS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43707
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8061-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
coronary artery disease	GWASdb SNP-Disease Associations	1.0	0.843827
PROB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65775
HOXC9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6692
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4970-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174701_5_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SEL1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11768
RCOR1	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-5670-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6134-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM61	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52862
anteroventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26791
ANKRD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75204
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.6886
SLC26A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05019
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.974372
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.839577
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ATG4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.443
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
c-fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.347587
Fog2_KO_GDS3659_152_mouse_adult heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
intermediate stratum of p1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11221
hsa-miR-3670	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100355_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.68397
IRF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	107.75
myb_16205643_primary_monocytes_gof_human_gpl570_gse2816	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.011207
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.74046
A-673	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13259
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.101
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.4165
496100388_HIP_probable Alzheimer's disease_no TBI_87_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.0865
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
germ layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058464
hsa-miR-4310	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PMC9174882-EMMM-14-e15816-s004.xlsx-MYC_GeneSigs-DANG_BOUND_BY_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
CD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7951
YAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08865
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.225
DNAJB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16232
SNU81	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64631
Metabolic syndrome	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
TAF6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.286
BPGM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62144
bone marrow	HPA Tissue Protein Expression Profiles	1.0	1.2595
HdhQ111/111_Knock-in_GDS4534_744_mouse_Striatum and cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055203
hsa-miR-2052	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76981
Olfactory organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.223
PCGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03756
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1943
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GM-06B-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DK-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALYREF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30908
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
overnutrition	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043034
Kidney Chromophobe_KICH_TCGA-KL-8329-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ICC2	DepMap CRISPR Gene Dependency	1.0	2.97248
intermediate stratum of m1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10502
centrosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.214714
GSE111247_11_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STK10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67991
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.016
GSE70935_3_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1677
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8792
RNASEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75488
C1QBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92318
Nasal cavity	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.028
ZNF789	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91925
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86026
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPZOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45379
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.288
MGAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36072
Subparafascicular nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06174
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A85H-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	68.972
GSE201239_6_v_7_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sensory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.143
Oral apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.6
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1666	CCLE Cell Line Gene CNV Profiles	1.0	1.59789
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.624885
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, dorsal zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.7551
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.3333
Postsynaptic cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.89
Infralimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00694
anteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22913
reticular formation of p1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11221
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042686
all	GWASdb SNP-Phenotype Associations	1.0	0.028771
Acute Myeloid Leukemia_LAML_TCGA-AB-2931-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49518
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.88
hsa-miR-4268	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Gliosarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.036
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.06396
HCC15	CCLE Cell Line Gene Expression Profiles	1.0	1.82556
hsa-miR-4723-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08119
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2871
ZNF682	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81137
ZNF280C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16951
hsa-miR-623	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051967
USF	MotifMap Predicted Transcription Factor Targets	1.0	null
CEBPB-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53996
C8orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77473
CISD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92349
PFDN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.27682
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2915
SA1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MTMR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75577
USP27X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62236
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
PRMT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04765
chr13_38993468_C_A_b38	GTEx eQTL 2025	1.0	1.05071
GSE235120_1_v_0_pidd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SERTAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28462
periventricular stratum of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18634
m2 part of pararubral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52735
TGF-beta_OE_GDS2974_137_mouse_corneas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857177
bardet-biedl syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.23386
Leaflet of membrane bilayer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.647
r4 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42727
NBEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3675
IKZF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22616
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1453
M-1	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.64463
Spinal nucleus of the trigeminal, oral part, ventrolateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70222
PMC5787244-13229_2018_191_MOESM1_ESM.xlsx-FOXO1_GSEA_txt-PROBE_FOXO1	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14506
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.45441
nucleus of the inferior collicular brachium, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9019
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.868874
MAP3K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05967
FGFR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1536
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.942289
PATU8988S	CCLE Cell Line Gene Expression Profiles	1.0	1.55403
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
EZH2	ENCODE Transcription Factor Targets	1.0	null
TRMT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.93359
Infertility, Male	CTD Gene-Disease Associations	1.0	1.12973
Brain Lower Grade Glioma_LGG_TCGA-HT-A74H-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HT55	CCLE Cell Line Gene Expression Profiles	1.0	1.69153
496100635_HIP_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25562
hippocampus (hippocampal formation)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.46428
RAPGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68867
KIF20B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52762
THOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11508
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A184-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mediodorsal nucleus of the thalamus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22532
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-7823-01B-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08344
ZNF598	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40169
SKUT1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54434
GSE239541_8_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of r1Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55303
Intracranial hypotension	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
ST486	CCLE Cell Line Gene Expression Profiles	1.0	2.05224
Slit diaphragm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.584
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2538
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.50149
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C6orf132	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.84766
intermediate stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09742
Lung adenocarcinoma_LUAD_TCGA-55-6985-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4831
ARIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17187
hsa-miR-570	TargetScan Predicted Conserved microRNA Targets	1.0	0.517189
SMAD3-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
WSU-FSCCL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22852
PLXNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.674
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.23605
Acute Myeloid Leukemia_LAML_TCGA-AB-2986-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4659a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.908669
HCC2218	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36239
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044055
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.231
PROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26903
HOXC12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4383
ORC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29707
TRA2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28008
NCI-H2369	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857667
first (dorsal) preoptic domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47115
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.4091
ELOVL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02999
fallopian tube	HPA Tissue Protein Expression Profiles	1.0	1.2595
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A57M-01A-51R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05219
M140325	DepMap CRISPR Gene Dependency	1.0	3.54802
ZNF570	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58983
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4685-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.063295
Facial neuralgia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.257
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
TGFBR2_knockout_292_GSE46150	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.40895
Distal arthrogryposis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.759
EMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87587
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hydrogenosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.025
Lobule II, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16004
496100392_HIP_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.93377
H3K36me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Usp22_DEPLETION_GDS4973_284_mouse_E14 embryonic stem cells (ESCs)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
separase-securin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.525
POTEI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90059
posterior (ventral) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00012
septum (resp epith)	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
MAFF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60559
Arteries	dbGAP Gene-Trait Associations	1.0	0.20026
CCDC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28801
inner SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.982326
LITAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85597
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10196
Periplasmic side of cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.755
NCI-H1651	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8165-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-548ab	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8725
Anterior olfactory nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18132
PDSS2_KO_GDS3454_120_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Olfactory nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.972
ARL4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56362
HS870T	CCLE Cell Line Gene Expression Profiles	1.0	2.51506
MAP3K1_knockout_245_GSE39240	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.50531
GSE203308_9_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BL5254 (TAF3)	NURSA Protein Complexes	1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3627
Perturb_12129_KO_IslandsH/Lipsi/Sfaktiria_SRP136181	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.23972
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE208096_1_v_0_progesterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EIF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59208
APOBEC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28111
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_1day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.05388
EIF1AY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31995
Cytoproct	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.005
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3ML-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73941
TJP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61827
Parabrachial nucleus, lateral division, ventral lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0791
intermediate stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67023
TMBIM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19775
lymph node	HPA Tissue Protein Expression Profiles	-1.0	-0.766156
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6934-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EFM19	DepMap CRISPR Gene Dependency	1.0	2.05828
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.980684
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.60038
GLYATL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60813
inner CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.919622
Retrosplenial area, ventral part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01462
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.9638
hsa-miR-1286	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Diabetic neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.568
CBX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35893
TMSB4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83614
abnormal mechanical nociception	MPO Gene-Phenotype Associations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.884234
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81415
cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18076
496100470_HIP_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	5.2092
IKZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7216
MANSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00812
Ciliated cell_Lung_Human	CellMarker Gene-Cell Type Associations	1.0	null
hippocampus (hippocampal formation)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.825661
NKX2-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77096
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-G8-6326-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dorsal peduncular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49882
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3737
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.913
Spz1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4167
red nucleus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01651
hsa-miR-548n	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.101
ZNF175	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6077
COLO201	CCLE Cell Line Gene CNV Profiles	1.0	1.45685
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.061942
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Impaired Cognition	DisGeNET Gene-Disease Associations	1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.284
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.24678
Caveola	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.605
Lung adenocarcinoma_LUAD_TCGA-44-6148-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTARC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78623
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.989181
SUM52PE	DepMap CRISPR Gene Dependency	1.0	2.21659
Lung squamous cell carcinoma_LUSC_TCGA-43-6773-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pupa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.761
TIGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75784
Intrinsic component of cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.754
SH2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55
CTDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15524
TMEM94	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05046
CEBPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80217
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.061639
GSE129241_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3365-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6081
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
dorsal part of alar p3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06213
Olfactory epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.675
YMB1	CCLE Cell Line Gene Expression Profiles	1.0	1.37295
PMC11772884-41421_2024_747_MOESM6_ESM.xlsx-7_DEGs_USF2-KO_vs_control-Gene_Symbol_USF2	Rummagene Transcription Factor Associations 2026	1.0	null
DCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31563
OVSAHO	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68909
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.942458
SEPTIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69655
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
posterior paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18178
MON	DepMap CRISPR Gene Dependency	1.0	3.67865
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47884
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
PGM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84771
integument phenotype	MPO Gene-Phenotype Associations	1.0	null
SIX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73998
Spinal nucleus of the trigeminal, oral part, caudal dorsomedial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70222
cell projection	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7094
hsa-miR-1915	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
Hematopoietic system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
FZD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77944
Rectum adenocarcinoma_READ_TCGA-EI-6508-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2042
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05322
METTL7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88016
Peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.948
inner CP in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.834176
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
CMTM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75634
Third cranial nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.208
septal organ	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.4376
hsa-miR-520d-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
HUO9	DepMap CRISPR Gene Dependency	1.0	4.19172
Linear nucleus of the medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29736
Lung squamous cell carcinoma_LUSC_TCGA-56-7730-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TANGO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00308
PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_12_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44194
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-548h	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
mediodorsal nucleus of thalamus_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.53753
Perivascular astrocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.646
NKX2-8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79801
r5 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16435
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A1X3-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1056
SG in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14463
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5703-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NIF3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90755
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.99959
Lung squamous cell carcinoma_LUSC_TCGA-90-7767-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mesenchyme	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.244232
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78766
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
liminal alar domain of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0266
subethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46642
MUTYH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57891
Primary somatosensory area, lower limb, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37039
TCF3/E2A-22897851-JUKARTE6-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EBF1-22473956-BONE-MARROW-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02213
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-13q34_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
ETV2::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4765
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
cellular_component	GO Cellular Component Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-A46K-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal peduncular cortex, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5844
A-Netherlands-602-2009(H1N1)_48Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	3.0893
GSE70499_5_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29259
Gliosarcoma	DisGeNET Gene-Disease Associations	1.0	null
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058557
SUMF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74356
C-fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.602
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9894241-pnas.2211429119.sd05.xlsx-G8_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
RAB40AL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.38029
PAX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68869
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81415
primary somatosensory cortex (area S1, areas 3,1,2)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47161
Regio orbitalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.74
SK-MEL-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23611
caudal subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09071
SURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62805
r4 part of reticulotegmental nucleus, shell portion	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21691
KMS-12-PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.967021
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.05115
OXLD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28609
HCC2218	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07292
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Anther	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.908
Precommissural nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17194
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.899236
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
lung	HPA Tissue Gene Expression Profiles	1.0	1.23769
ZKSCAN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55312
neuron part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04764
LOXIMVI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4653-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.0037
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.7533
ES4	DepMap CRISPR Gene Dependency	1.0	2.95724
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MFE280	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49941
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82354
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18303
CAR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
disease of metabolism	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6688
HCC1576	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61964
Perturb_2272_KO_Mettl3_SRP110576	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.73223
CALU1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.49034
BICR10	DepMap CRISPR Gene Dependency	1.0	2.36444
KLE	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15135
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.837183
LATS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4429
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-664	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
MAP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92043
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TRAPPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20013
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
superficial stratum of m2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00129
ALEXANDERCELLS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.67821
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884573
Seed coat	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
signal transduction	GO Biological Process Annotations 2015	1.0	null
PRELID3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11171
outer SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.43083
JMY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57921
Carcinoma, Ovarian Epithelial	DisGeNET Gene-Disease Associations	1.0	null
Nerve plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.944
AKAP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11739
ZMYM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80734
C1orf159	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70926
PAQR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31784
ZNF354C	JASPAR Predicted Transcription Factor Targets	1.0	null
PHF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20959
KO52	CCLE Cell Line Gene CNV Profiles	1.0	1.89627
ASPHD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05433
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.970983
POLR2A	ENCODE Transcription Factor Targets	1.0	null
SATB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18576
r2 part of median raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14447
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07135
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.635248
GSE232631_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2937-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Oculomotor nerve paralysis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.276
septodiagonal transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13743
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.845189
RHOB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92174
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0499
GSE165682_2_v_5_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TNFAIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40982
FOXO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64776
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.970983
SLC37A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37905
Ebolavirus(ZEBOV)_3day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.33639
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887052
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
SUPT20H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74017
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76455
ZNF582	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16346
ac2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.587
KMBC2	CCLE Cell Line Gene CNV Profiles	-1.0	-3.20971
ICMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12997
CLDN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27842
REST-19997604-NEURONS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NUP50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85684
EHBP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71285
CELSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58066
DCTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89637
UMUC1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.63202
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0109
Disease by infectious agent	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.908207
Kidney Chromophobe_KICH_TCGA-KN-8434-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
TBX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53115
Cell outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.289
MEX3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67507
Choanomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.337
malignant glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.364085
SPI1-20517297-HL60-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Medial preoptic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06252
Lung squamous cell carcinoma_LUSC_TCGA-56-7579-11A-01R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.3663
SLAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58844
496100529_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.72519
ANGEL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56338
r3 part of reticulotegmental nucleus, shell portion	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.62299
ZNF81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19508
central part of MD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49344
anterior pretectal nucleus, dorsal core part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09662
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041955
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86026
496100433_HIP_probable Alzheimer's disease_TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.50636
TT2609C02	CCLE Cell Line Gene Expression Profiles	-1.0	-1.96689
mantle zone of r4Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.44467
Nucleus of the lateral olfactory tract, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19213
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A3-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal mechanical nociception	MGI Mouse Phenotype Associations 2023	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14882
Lung adenocarcinoma_LUAD_TCGA-55-8513-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
m1 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43815
NCIH3255	CCLE Cell Line Gene Expression Profiles	-1.0	-2.5148
BAZ2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19351
coronary artery disease	GWASdb SNP-Phenotype Associations	1.0	0.738585
hsa-miR-122	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.09606
Stomatin-like protein 3	InterPro Predicted Protein Domain Annotations	1.0	null
MDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24321
MOSPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.454
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3324-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71811
VHL_Deficiency_GDS3769_513_mouse_Immortalized embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SPI1	ChEA Transcription Factor Targets	1.0	null
PDCD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37168
PANC 03.27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846109
atherosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.311386
GSE191138_3_v_0_fmo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prader-Willi Syndrome	DisGeNET Gene-Disease Associations	1.0	null
periventricular stratum of DTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03936
PTAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5048
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73R-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.668
ZNF205	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08363
FAM156B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02947
nucleus of the stria medullaris (prethalamic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06411
LMBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23871
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.11377
FOXD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.3979
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11295
COLO678	CCLE Cell Line Gene CNV Profiles	1.0	1.42181
SH10TC	DepMap CRISPR Gene Dependency	1.0	2.06402
JDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18501
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04057
lung	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
LS513	CCLE Cell Line Gene CNV Profiles	1.0	1.57098
DTX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04954
105KC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.996515
SIRT3_KO_GDS4058_16_mouse_BROWN ADIPOSE TISSUE	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MCM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05929
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SIK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67083
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06466
NHLRC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74806
CEBPB-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-2.30892
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5199-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04115
Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7021771-41467_2020_14684_MOESM7_ESM.xlsx-CASZ1_ChIPseq_in_SMS-CTR_MEKi-Nearest_Ensembl_CASZ1	Rummagene Transcription Factor Associations 2026	1.0	null
RTCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94591
superficial stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96376
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LTA4H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0555
UBLCP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69685
UBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51266
Dorsal motor nucleus of the vagus nerve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1002
ZSCAN4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4075
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	1.2595
SRY	ChEA Transcription Factor Targets	1.0	null
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04003
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.6914
Aedesaegypti	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
A673	CCLE Cell Line Gene CNV Profiles	1.0	1.35802
Apical cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.693
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
prethalamic eminence	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06294
PMC10679662-mmc2.xlsx-NC-D3-ZEB2-siRNA-Upregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
KYO1	CCLE Cell Line Gene Expression Profiles	1.0	2.01483
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6955-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer 1 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91559
layer 3 of CCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0791
SK-MM-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0915
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.79145
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.14031
Nemaline myopathy 5A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.128
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.4926
STRN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87622
RADX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30539
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.109
P31FUJ	CCLE Cell Line Gene CNV Profiles	1.0	1.69047
Lyf-1	MotifMap Predicted Transcription Factor Targets	1.0	null
MRPS30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50904
GOLT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59797
Bleb	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.73
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
CAV1	Pathway Commons Protein-Protein Interactions	1.0	null
496100480_HIP_no dementia_TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.96216
FAM229A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63719
Nucleus of the brachium of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44103
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14824
TMEM186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29394
HCC366	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40378
BCAS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27404
PTPN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98953
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36466
FBXO45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51507
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21948
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
A2058	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.887052
superficial stratum of PcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35885
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.42027
abnormal response to tactile stimuli	MPO Gene-Phenotype Associations	1.0	null
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.293278
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-2608-01A-02R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACBD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61299
SOD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74504
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78109
VIPAS39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30656
Encephalomyelitis	DisGeNET Gene-Disease Associations	1.0	null
HIVEP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33027
PMC2263127-pone.0001816.s001.xls-E2F3_down_Bild-Symbol_E2F3	Rummagene Transcription Factor Associations 2026	1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.66373
MAP3K20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34614
scale	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.257572
TUBB4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69499
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CYSRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53232
IQGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53631
UXT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36213
RAB6C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3418
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9486
LTBR_INHIBITION - 2 Days_GDS2005_729_mouse_Lymph nodes  (MG-430B)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cochlea	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.392
EP300	ENCODE Transcription Factor Targets	1.0	null
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.6926
QPCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43303
VAV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45258
FBXL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88016
membrane region	GO Cellular Component Annotations 2015	1.0	null
CALB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42463
abnormal nerve fiber response	MPO Gene-Phenotype Associations	1.0	null
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.101
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.612
STAT3	ENCODE Transcription Factor Targets	1.0	null
CRBN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40974
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10196
TERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59294
BICR18	CCLE Cell Line Gene CNV Profiles	1.0	1.52292
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
zfpm2_19411579_heart_lof_mouse_gpl1261_gds3659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.676547
A_CA_04_2009_4dayMOI-10^3_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.16312
CRIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19662
JAGN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71703
hsa-miR-532-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
hsa-miR-4736	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Plasma membrane raft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.602
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.7952
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08243
mesenchymal	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-4447	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
WSU-NHL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31784
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.954303
r8 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2008
Perturb_8901_KD_STIM1_SRP128928	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.35466
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.736
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.049173
MROH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87035
CSNK1G3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56305
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3872
LAYN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2792
ZFP41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78596
AKT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73399
abnormal involuntary movement	MPO Gene-Phenotype Associations	1.0	null
SCARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30169
EHMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92291
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49348
ZNF395	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74785
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SR-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Germinated grain	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.837
ZNF589	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51569
TE9	CCLE Cell Line Gene CNV Profiles	1.0	1.84792
OE33	DepMap CRISPR Gene Dependency	1.0	2.00992
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.101
Lung adenocarcinoma_LUAD_TCGA-55-6978-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50551
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
JHH2	CCLE Cell Line Gene Expression Profiles	-1.0	-1.67146
Globus pallidus, internal segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24939
RAB3A_KO_GDS2483_700_mouse_Cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TE8	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9418
abnormality of the vasculature	GWASdb SNP-Phenotype Associations	1.0	0.102183
hsa-miR-4729	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.052297
C5orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21441
Rectum adenocarcinoma_READ_TCGA-EI-6885-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
lateral terminal nucleus of the accessory optic tract, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16947
CRABP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89782
SDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8462
Lung adenocarcinoma_LUAD_TCGA-49-6742-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane raft	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
PUM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01743
LRRC57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73521
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26998
RNF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57431
TNS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74201
Lung adenocarcinoma_LUAD_TCGA-44-6147-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Transport of small molecules	Reactome Pathways 2024	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40896
nucleus of the inferior collicular brachium, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21487
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3139
neuron projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.07456
HSPA1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30301
EIF4E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94369
CYBRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58902
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_30_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.0321
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14431
APH1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79192
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043474
Uterine Carcinosarcoma_UCS_TCGA-N9-A4Q1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tanycyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.545
subbrachial nucleus, rostral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5239
Flotillin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.848
periventricular stratum of JcPV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09539
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4642-01B-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF628	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40601
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-1.18472
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9482
ZNF140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.877
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
C1orf198	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82549
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.082632
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7130-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_987_KO_Eed_SRP092111	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.33879
MM383	DepMap CRISPR Gene Dependency	1.0	10.1933
RFX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05043
KRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63851
abnormal nervous system physiology	MPO Gene-Phenotype Associations	1.0	null
bronchus	HPA Tissue Protein Expression Profiles	1.0	1.2595
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.948988
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05322
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5606
B4GALNT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94054
KCTD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94864
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Lung squamous cell carcinoma_LUSC_TCGA-22-5479-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5028-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF224	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62402
IRF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sox5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9597
STK26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17161
primary motor cortex (area M1, area 4)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.956611
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07851
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.55485
GSE174383_1_v_5_ly6d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Superior colliculus, motor related, intermediate gray layer, sublayer c	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28537
GSE114013,GSE114014_0_v_3_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cribriform plate	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.826
HOXC13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5358
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.87186
BV-173	COSMIC Cell Line Gene Mutation Profiles	1.0	null
isthmic part of basolateral isthmic reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16937
ZNF174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53564
NACAD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85549
Adrenocortical carcinoma_ACC_TCGA-OR-A5K2-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03753
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
ZFP62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46573
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.406
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42155
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17617
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.30233
FAM120AOS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80984
Lung adenocarcinoma_LUAD_TCGA-38-A44F-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21014
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14882
Nasal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
RPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16936
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.423
Lung adenocarcinoma_LUAD_TCGA-75-7025-01A-12R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15883
496100539_HIP_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	4.50391
Gata-6_KO_GDS4782_330_mouse_Adult heart during pressure overload	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Integral component of Golgi membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.578
UAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62178
KCTD15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38638
NCIH2291	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87078
Spinal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.471
Lung squamous cell carcinoma_LUSC_TCGA-22-1005-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus of the lateral olfactory tract, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38157
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18555
MS751	DepMap CRISPR Gene Dependency	1.0	2.3075
NTF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69082
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	49.448
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HTRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64328
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3547
NCI-H841	COSMIC Cell Line Gene Mutation Profiles	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.39312
superficial mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11444
RNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84807
Lung adenocarcinoma_LUAD_TCGA-55-8204-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160817_0_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ae1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.105
Contractile vacuolar membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.917
microtubule cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.175745
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-564	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NHERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28469
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11931
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Cranial ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.128
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC9A3_KO_GDS3323_495_mouse_colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
JHH7	DepMap CRISPR Gene Dependency	1.0	2.83203
MRPL52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06382
Visceral hump	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
BBSome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.103
METTL26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82773
intermediate stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47504
Lung squamous cell carcinoma_LUSC_TCGA-21-5784-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.070664
r5 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99014
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1975 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
hsa-miR-516b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
APP	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7784-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lateral habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00733
PMC4872452__F2	PFOCR Pathway Figure Associations 2023	1.0	null
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
outer SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21628
Glomerular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.938
SLC25A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4549
TP63	ChEA Transcription Factor Targets	1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.23224
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.75344
TCP10L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26109
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC9941047-41591_2022_2163_MOESM3_ESM.xlsx-ST12-Unnamed_1_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
SPRR2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57296
496100597_HIP_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.49635
GATA1	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Distal arthrogryposis type 5	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.059
MPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54159
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13603
KMS26	CCLE Cell Line Gene Expression Profiles	1.0	1.90394
CYFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45773
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07912
HCC1833	CCLE Cell Line Gene Expression Profiles	-1.0	-2.14284
AMOTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38377
ATG4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28079
mantle zone of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13968
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19429
Matrilin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.635
MTERF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62874
superficial stratum of m1AL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52722
U118MG	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03639
MPZL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.388
hsa-miR-4659b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
EEF1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47438
preoptic telencephalon	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06036
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0329
A-Vietnam-1203_CIP048_RG3-2004(H5N1)_7Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.45328
496100294_HIP_possible Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.87386
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14021
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Dorsal peduncular area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.30759
FBXL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06321
496100584_HIP_probable Alzheimer's disease_no TBI_95-99_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.27537
GSE201239_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GNAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50973
hsa-miR-520f	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
abnormality of the systemic arterial tree	GWASdb SNP-Phenotype Associations	1.0	0.142626
ALPK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75942
primary visual cortex (striate cortex, area V1/17)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.836854
BARHL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3934
RRAGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89341
early endosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.280716
NCIH508	CCLE Cell Line Gene CNV Profiles	1.0	2.32859
horizontal nucleus of the diagonal band, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25192
JcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.82006
abnormal motor capabilities/coordination/movement	MPO Gene-Phenotype Associations	1.0	null
GSE160817_7_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5861
RAGE_knockout_269_GSE22873	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.76833
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.03191
Perturb_15285_KO_Trp73_SRP067006	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.25572
SERPINB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89918
ECC12	CCLE Cell Line Gene CNV Profiles	-1.0	-1.5163
aa94	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.245
Maxillary nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
Lung adenocarcinoma_LUAD_TCGA-44-6148-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41677
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MED12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.3298
Caryopsis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.894
hsa-miR-1260	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48131
SKBR3	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.932045
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.545
Peripheral ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.47
OLIG2-23332759-OLIGODENDROCYTES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PSMC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10003
basointermediate isthmic reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42373
amygdaloid complex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.90064
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.996504
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08525
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70J-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE178714_5_v_7_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MJ-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.959223
DCUN1D4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71794
TCEAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11564
SPATA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70325
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1087
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37887
Lung squamous cell carcinoma_LUSC_TCGA-56-7221-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57094
RLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55566
GSE195713_0_v_1_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GLO1_OE_GDS4991_546_mouse_anxiety disorders	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.1356
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
ITPKC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62407
CEBPB-26923725-CHIP-SEQ-MESODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Anteroventral nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33971
ZNF713	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39699
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.2899
MSANTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89872
lateral intermediate part of entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.29023
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196199_0_v_1_zbtb20_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH520	CCLE Cell Line Gene Expression Profiles	1.0	1.59
NR3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94227
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16695
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
hsa-miR-494	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Membrane raft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.736
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2167
KAT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67541
GSE240344_1_v_0_uxs1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
FAM78A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6839
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_7Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.3309
MEIS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77985
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.82649
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3766
RAB11FIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30184
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHAX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26234
Corpus allatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.878
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.294
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of PThE	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06294
periventricular stratum of TG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00129
GA10	CCLE Cell Line Gene Expression Profiles	1.0	1.50925
FERD3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03761
Perturb_14003_OE_Kcna2_SRP309478	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19398
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.896407
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.975543
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.63666
METAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69114
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11859
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35618
Rhinencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
Golgi trans cisterna	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.024
SLC35E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12272
Anterior olfactory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10756
Neuropathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.335
primary auditory cortex (core)_25 pcw_F_12948	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10006
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
HMX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30624
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE116580_0_v_1_smug1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.92313
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05775
astrocytoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.499997
ventrolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.18015
ZNF558	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23438
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3195
ARC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74575
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.33959
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
A-Netherlands-602-2009(H1N1)_7Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.60439
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Posterior cell cortex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.098
Nasal mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.618
ZSCAN16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15186
PDGFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88412
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69085
intermediate stratum of r1Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03008
dorsal part of m1A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24852
SNU-449	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51363
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.30638
Perturb_15284_KO_Trp73_SRP067006	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.29044
mesenchymal cell neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	1.16008
hsa-miR-129-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
m1AD (DM) part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52056
hsa-miR-942	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
ethmoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74976
HOXD12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0898
periventricular stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52103
RAI14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88474
Nkx3-1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.6362
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.085
JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7215
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0992
interanterodorsal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.0614
ARHGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22357
NR3C1	ChEA Transcription Factor Targets	1.0	null
NLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51904
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.258
EBPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14117
RUFY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35245
island of Calleja major	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02426
ADCY3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE114690_2_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.974785
SOX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92922
CIITA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85308
Dorsal peduncular area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03996
CAV1	Hub Proteins Protein-Protein Interactions	1.0	null
laminin-5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.936
axon	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.121855
ZNF121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55748
KLRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9212
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.833334
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10872
ovary	HPA Tissue Protein Expression Profiles	-1.0	-0.766156
H3-7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36212
TMEM92	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7817
MFE319	CCLE Cell Line Gene Expression Profiles	1.0	1.53782
Ikzf3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6619
pyramidal cells of rostral CA4	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0552
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
hyporesponsive to tactile stimuli	MGI Mouse Phenotype Associations 2023	1.0	null
klf7_17123745_olfactory_epithelium_lof_mouse_gpl1261_gds2069	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.384426
CCAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66246
hsa-miR-548i	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
hyporesponsive to tactile stimuli	MPO Gene-Phenotype Associations	1.0	null
rt1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.668
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053872
Vomeronasal organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.713
Inner mitochondrial membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.521
ChIP_PRDM14_21183938	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Angelman Syndrome	DisGeNET Gene-Disease Associations	1.0	null
Bardet-Biedl syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.295
PABPC1L2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88186
PDIK1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2561
SIRT3_KO_GDS4058_454_mouse_BROWN ADIPOSE TISSUE	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ZNF175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30722
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.101
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.79
CGRP receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.515
HOXB9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1413
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SU-DHL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.082
Trigeminal nerve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.069
ZNF276	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92773
Hippocampus minor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.881
PA1	DepMap CRISPR Gene Dependency	1.0	2.97939
hsa-miR-548y	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.07636
ZBTB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.02947
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.716
Childhood Gliosarcoma	DisGeNET Gene-Disease Associations	1.0	null
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22714
Band 7 protein	InterPro Predicted Protein Domain Annotations	1.0	null
membrane region	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.003506
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043898
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
WDFY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65677
Trachea	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Vestibular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.386
NR3C1-21868756-MCF10A-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SURF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41019
ZNF71	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00824
PAFAH1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82857
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2746
KLM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.99219
mantle zone of PThE	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06294
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32091
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34479
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51T-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3R1-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Stimuli-sensing channels	Reactome Pathways 2024	1.0	null
GSE217541,GSE217543_3_v_2_tet1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Dendritic knob	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.747
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.052
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intermediate stratum of ITTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.74867
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.11931
mantle zone of m2Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0274
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Ciliary membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.17
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.58837
TC-71	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11555
GSE211177,GSE211178_4_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sensory dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.915
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.59596
CKMT1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88018
U266B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54434
MFSD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1538
Ebolavirus(ZEBOV)_6day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-3.55252
Nerve trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.521
SNU119	CCLE Cell Line Gene Expression Profiles	-1.0	-3.48756
MAPKBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37815
FOXO1::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.2602
ZSCAN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28891
SW1463	CCLE Cell Line Gene CNV Profiles	1.0	1.75352
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A86F-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBC1D24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55832
SAMD10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19323
MRPL39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3057
METTL21A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2918
SCN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42733
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.81415
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99265
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25192
Spinal nucleus of the trigeminal, oral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.53598
TP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37498
Lung squamous cell carcinoma_LUSC_TCGA-98-A53H-01A-12R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MMP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17802
SPIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.489
CTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37441
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A5BD-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ABCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57807
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HOXD11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0322
mantle zone of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46753
Hypoglossal nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.565
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SL-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pedunculopontine nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86255
ZNRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82246
DNAJB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21101
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.92962
OCUM1	CCLE Cell Line Gene CNV Profiles	1.0	1.39207
deferoxamine_homo sapiens_gpl13497_gse30774	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06537
periaqueductal gray substance, ventral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.950992
hsa-miR-1260b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Lung adenocarcinoma_LUAD_TCGA-91-6849-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3763
NDUFAF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7873
GSE114232_8_v_6_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMED7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98354
CLIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67258
DUS3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20478
FRAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21366
SHARPIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61251
CBY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80036
DPYSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85741
Stomatin family	InterPro Predicted Protein Domain Annotations	1.0	null
TE-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormalities of the peripheral arteries	GWASdb SNP-Phenotype Associations	1.0	0.249501
ETV5::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5765
RFNG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37717
Lateral group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02538
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.754122
ARFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23625
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
PMC7889611-41467_2021_21346_MOESM10_ESM.xlsx-High_TSA_score_correlations-Supplementary_Data_6_Genes_with_expression_that_positively_correlate_with_a_high_TSA_score_in_AIRE_and_corneocyte-like_mTECs_AIRE	Rummagene Transcription Factor Associations 2026	1.0	null
Band 7/stomatin-like, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
496100434_HIP_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.72438
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A855-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.1321
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	2.24804
abnormal touch/ nociception	MPO Gene-Phenotype Associations	1.0	null
H4C6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.70545
hippocampus (hippocampal formation)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.70991
PK59	CCLE Cell Line Gene CNV Profiles	1.0	1.35802
TM6SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22415
ATAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44099
r2 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03205
Rosette leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.956
Prostate adenocarcinoma_PRAD_TCGA-CH-5766-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15778_KO_Nmnat2_SRP360949	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.31283
MAPK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35964
NCI-H1944	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.60149
DICER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14569
COR-L321	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CLDN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76884
POLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59349
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.23805
EBF1	ENCODE Transcription Factor Targets	1.0	null
Fbxl10_OE_GDS4788_580_mouse_fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Ovary	GTEx Tissue Gene Expression Profiles 2023	1.0	5.13491
Lateral spinothalamic tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.797
MCF7	CCLE Cell Line Gene Expression Profiles	1.0	2.32962
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.447961
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01651
DNAJC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58217
pancreas	HPA Tissue Protein Expression Profiles	-1.0	-0.766156
Adrenocortical carcinoma_ACC_TCGA-OR-A5J1-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5471-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF3	ENCODE Transcription Factor Targets	1.0	null
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18646
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Lung adenocarcinoma_LUAD_TCGA-55-6986-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-2116	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SLC7A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85958
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.12263
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66595
Bam protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.755
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.82649
hsa-miR-1248	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Spinal nucleus of the trigeminal, oral part, middle dorsomedial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3964
ZNF462	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65597
PLPP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16145
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6537
PDLIM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59669
microtubule organizing center part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.482064
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.19038
inferior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.893979
STX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84735
SKOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93502
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23246
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04787
SLITRK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68817
MT-CO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55461
Microtubule bundle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.995
A-CA-04-2009(H1N1)_7Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.32033
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8478
peripheral nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.94867
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.896407
Hereditary Stomatocytosis	DisGeNET Gene-Disease Associations	1.0	null
PDIA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2039
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.027808
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JG-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-5645-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parabigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.7278
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.834022
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65882
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.86806
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06466
NCIH1623	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59681
ROS50	DepMap CRISPR Gene Dependency	1.0	5.51939
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5836-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PIGC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26374
H3K27me3_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ESCO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61561
RASSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17322
periventricular stratum of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34017
orbital frontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23582
nervous system phenotype	MPO Gene-Phenotype Associations	1.0	null
HES7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51707
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T47D	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.37767
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.80668
STRIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03989
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11612
USP53	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31585
COLO205	CCLE Cell Line Gene CNV Profiles	1.0	2.26293
P53-22387025-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC7165319-3896263.f6.xlsx-List_of_significantly_diffenent-Significantly_different_proteins_between_AA_pool_and_CON_pool_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XL-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40427
CACNA2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36247
ANKLE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11469
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PQ-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.114
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2794
GMPPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46566
Erg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.4886
ZNF181	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85926
A3KAW	CCLE Cell Line Gene Expression Profiles	1.0	2.12441
ZNF688	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87239
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43312
Ethmoid bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.809
Olfactory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
DUSP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19107
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZK-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-2355-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
JHH-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857177
CYB5R3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38376
hsa-miR-340	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.846689
LU165	DepMap CRISPR Gene Dependency	1.0	4.24329
cytoskeletal part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.063556
Contractile vacuole pore	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.092
hsa-miR-4677-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
CCDC120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76423
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.9953
TMEM9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28271
centriole	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.519389
abnormal nerve fiber response	MGI Mouse Phenotype Associations 2023	1.0	null
Respiratory mucosa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.591
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1448
CASP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67516
Major island of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21691
GSE201239_0_v_7_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.68101
496100619_HIP_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.16406
JHOS4	CCLE Cell Line Gene CNV Profiles	1.0	1.96146
ETV2-25802403-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.828439
Midline group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19213
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5374
Peripheral nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.052
small intestine	HPA Tissue Protein Expression Profiles	1.0	1.2595
MHHCALL4	CCLE Cell Line Gene Expression Profiles	1.0	1.58072
intermediate stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44103
Ventral tegmental area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05192
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5008-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3342
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01084
TBP	ENCODE Transcription Factor Targets	1.0	null
PRDM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17615
ST6GAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38403
SNU685	CCLE Cell Line Gene Expression Profiles	-1.0	-1.66072
Corpus cardiacum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.665
DPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98231
SMAD9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32051
BL8882 (SIRT6)	NURSA Protein Complexes	1.0	null
GJD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34505
DAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57298
PMC8944338__F4	PFOCR Pathway Figure Associations 2024	1.0	null
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8923
PLEKHG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45158
PLOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85513
496100471_HIP_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07073
r1 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55303
Satellite glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.547
OLIG2	ChEA Transcription Factor Targets	1.0	null
acquired metabolic disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RILPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21253
Parabrachial nucleus, medial division, external medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19398
Ion channel transport	Reactome Pathways 2024	1.0	null
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15722
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEP20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04624
GAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44483
MDAMB157	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36806
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ESRRB-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
COLO824	DepMap CRISPR Gene Dependency	1.0	4.55992
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
CDCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39502
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39623
Sto	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.086
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5B-Up_H3K4me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
abnormal sensory capabilities/reflexes/nociception	MPO Gene-Phenotype Associations	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-13q34_1_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
RASA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.33124
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846109
N4BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29388
HCA1	DepMap CRISPR Gene Dependency	1.0	4.47014
plasma membrane	LOCATE Curated Protein Localization Annotations	1.0	null
PASK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22601
septostriatal transition area (accumbens)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02039
artery disease	GWASdb SNP-Disease Associations	1.0	0.122692
Head and Neck squamous cell carcinoma_HNSC_TCGA-H7-A6C5-11A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE231641_0_v_1_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
layer IIIu of area 35r	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.88878
raphe obscurus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.955495
RNASE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37727
RCOR1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3444-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TRIM36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74561
ETCC016	DepMap CRISPR Gene Dependency	1.0	3.39691
hair-cell stereocilium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.835
ventral linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70005
Perturb_9448_KD_ESR2_SRP275562	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
DNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18047
differentiation	GeneRIF Biological Term Annotations	1.0	null
SLCO4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9602
TXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41458
MICOS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90259
Uroepithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.811
abnormality of the coronary arteries	GWASdb SNP-Phenotype Associations	1.0	0.311386
CCNQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80697
SW 1417	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965582
DMS53	DepMap CRISPR Gene Dependency	1.0	4.77637
Lung adenocarcinoma_LUAD_TCGA-99-8025-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56106
MKNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0734
PLC/PRF/5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.379
Ciliated epithelial cell_Esophagus_Human	CellMarker Gene-Cell Type Associations	1.0	null
hsa-miR-548ak	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.85953
MC1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19452
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.845655
Trigeminal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.034
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05181
SNU449	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74945
MZ in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05013
parvicellular (lateral) subparafascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18303
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.63682
Masseter	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.724
lateral preoptic area, PO1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55303
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.30993
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23611
SNAP47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25281
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.73142
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82067
Molting gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.071
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	2.88918
dorsal peduncular cortex, periventricular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07282
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A82C-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45708
RL	CCLE Cell Line Gene Expression Profiles	1.0	1.52804
CEBPB	ENCODE Transcription Factor Targets	1.0	null
SPPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21376
IZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.959692
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.838512
COLO800	CCLE Cell Line Gene CNV Profiles	1.0	1.63338
COLO792	DepMap CRISPR Gene Dependency	1.0	3.47986
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
microtubule organizing center	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.178877
SNUC1	DepMap CRISPR Gene Dependency	1.0	7.68621
Vascular cambium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
LU134A	DepMap CRISPR Gene Dependency	1.0	3.03228
CEBPB-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NOTO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27484
Nucleus of the solitary tract, commissural part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29863
TOP3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22237
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebral cortex	HPA Tissue Protein Expression Profiles	-1.0	-1.07311
Lung squamous cell carcinoma_LUSC_TCGA-43-7657-11A-01R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hair shaft	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.61
LDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27646
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.902692
hsa-miR-620	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
FIZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87066
FOXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27199
Medial geniculate complex, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33926
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary cutaneous amyloidosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.001
TDRKH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97979
membrane part	GO Cellular Component Annotations 2015	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057086
MOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39451
ZNF430	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6539
GSE157960_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
mantle zone of SeStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02039
insulin-like growth factor ternary complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.92
hsa-miR-4722-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.7008
SLC23A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79878
paraseptal subpallium	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16175
CFP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69619
CINP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22656
Johnston's organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.252
L428	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59681
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
nucleus sagulum, superficial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27216
accumbens nucleus, core domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34333
Lung adenocarcinoma_LUAD_TCGA-49-6745-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.6218
FDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51647
REST	ChEA Transcription Factor Targets	1.0	null
IRAK2_knockout_39_GSE10765	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.71453
SG in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.840146
r4 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.44467
GSE111247_11_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Dendrite terminus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.502
anterior nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15842
PEX26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5127
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.5402
arteriosclerosis	GWASdb SNP-Phenotype Associations	1.0	0.277486
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31784
mantle zone of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99014
KARPAS299	CCLE Cell Line Gene Expression Profiles	1.0	1.39346
ITFG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46308
2-iminoacetate synthase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.569
FBXL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84608
disease	GWASdb SNP-Disease Associations	1.0	0.024866
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03544
ventrolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.954303
GSE111247_14_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13832
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.896
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.878158
Lung adenocarcinoma_LUAD_TCGA-NJ-A55A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MED24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95572
Peripheral nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.271
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.079
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.858113
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.3413
posterior triangular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.1668
CHD1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69641
ZMPSTE24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18933
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.914936
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7053-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE70935_1_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54711
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.7381
OCIAML3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66124
Supratrigeminal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65882
fallopian tube	GTEx Tissue Gene Expression Profiles	1.0	1.51886
periventricular stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.82182
cilium	GO Cellular Component Annotations 2015	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sepal	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.743
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	69.422
glioblastoma multiforme	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.535796
KLF9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	85.7234
Distal arthrogryposis type 3	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.864
CCNJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.31669
Lung squamous cell carcinoma_LUSC_TCGA-63-A5M9-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.35448
HS 852.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04401
GTF2F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2033
TRIM27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6881
GSE114690_1_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Parasympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.524
496100381_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.39616
PDCD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36035
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.63919
DEDD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66932
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0915
PMC4051124-1471-2164-15-256-S16.XLSX-WES_IPD-RBCK1_2-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
LCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67369
GSE165647_5_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARHGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79696
NHE3_Deficiency_GDS3323_599_mouse_Colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.21047
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.99206
BCL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.98631
TPBG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59531
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.884075
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1752
RSU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67663
LPS510	DepMap CRISPR Gene Dependency	1.0	2.17264
H2AC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00805
EPHA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65462
BRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08346
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.673269
PTRHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81116
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18665
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.82124
GTF3C5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36185
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-1.45444
Daytime sleep phenotypes	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
WRAP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49276
TP63-23658742-EP156T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EEF1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72936
superficial stratum of m2ADL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27216
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27489
JAK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05473
MEAK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67826
Lung adenocarcinoma_LUAD_TCGA-91-6847-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perineurium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.541
Mesothelioma_MESO_TCGA-TS-A7P8-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.8013
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.42919
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.966423
JARID1B-DAIN-22020125-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D9-A6EC-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1641
CTCF	ENCODE Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.84463
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VDAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.9268
PEX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60337
PRKX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36928
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.53463
PKNOX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7125
RABIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07103
COLO320	CCLE Cell Line Gene CNV Profiles	1.0	1.68103
Prostate adenocarcinoma_PRAD_TCGA-CH-5794-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3439_KD_Ythdf2_SRP269726	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.17435
intermediate stratum of VTTh	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42291
FAM193A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1702
NCI-H2135	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.05419
NCI-H508	COSMIC Cell Line Gene CNV Profiles	1.0	3.12177
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	65.0008
cebpa_22442349_pbmc_lof_human_gpl570_gds4407	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.171792
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3636
H4C8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99858
UVSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36155
cell projection	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050248
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
Suprageniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.70369
TCF4	ChEA Transcription Factor Targets	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5296
NCIH647	DepMap CRISPR Gene Dependency	1.0	2.18528
Normocytic anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.155
UBE2G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04511
dorsolateral TG part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00129
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897238
molecular_function	GO Molecular Function Annotations 2015	1.0	null
HCT-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.40826
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.21882
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1270	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
core of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05192
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24462
vomeralnasalorgan.VMO.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
Herpes zoster oticus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.125
Hydrogenosomal membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.001
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96422
adult retina	HPM Cell Type and Tissue Protein Expression Profiles	-1.0	-1.17459
USP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07256
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.486
IGHMBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92427
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16396
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.969681
Anemia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.247
Alx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.9002
ventral paracommissural tectal nucleus, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44149
hippocampus (hippocampal formation)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.947493
mainolfactoryepithelium.MOE.	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01024
ADAM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14073
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.879956
LAMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.59931
GSE145323,GSE145324_1_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25192
NCIH69	CCLE Cell Line Gene Expression Profiles	1.0	1.66131
Lung squamous cell carcinoma_LUSC_TCGA-43-A56U-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HIF1A_DEPLETION_GDS2760_642_human_Hypoxic MCF-7 breast cancer cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Bolting stage	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.394
PPP1CC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38576
non-growing cell tip	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.94
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.953772
ARSI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42989
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9801
SNUC1	CCLE Cell Line Gene Expression Profiles	1.0	1.87018
ALG13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06482
H2BC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61778
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7699
PMC7165319-3896263.f6.xlsx-List_of_AA_outlier_pool-AA_outlier_pool_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00291
OTX2_01_268	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.82957
TIMM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44181
amygdaloid complex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.25107
GSE112763,GSE112767_0_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Omasum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.056
TGIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28901
FSCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83757
hsa-miR-1236	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
PVRIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41553
ZNF697	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12685
SW 1463	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45443
FBXW4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43182
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14575
NCI-H2073	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58278
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53567
hsa-miR-3116	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Retrosplenial area, ventral part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81317
hsa-miR-759	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Polycystin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.823
hsa-miR-548w	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Sarcoma_SARC_TCGA-X9-A973-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nutrition disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
CCNL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95316
SDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12569
OUMS23	CCLE Cell Line Gene CNV Profiles	1.0	1.41431
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26998
ETHE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27391
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.30294
Perturb_14505_KO_Tgfb3_SRP020224	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-18.2441
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18902
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19254
Transmembrane collagen trimer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.685
GSE111247_11_v_10_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5153
RBPJL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72889
PSORS1C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99858
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.07819
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.836854
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
abnormal pain threshold	MPO Gene-Phenotype Associations	1.0	null
IRF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.3143
NMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70284
CCDC25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74537
MECP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.602
organelle	GO Cellular Component Annotations 2015	1.0	null
NR3C1-21868756-MCF10A-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SERPING1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20142
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3111
ACSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47254
HCC1937	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.60238
POU6F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7076
ABHD17C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37783
VSIG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67989
DCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65705
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12827
RUNX2	ChEA Transcription Factor Targets	1.0	null
SKMEL24	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48236
KP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28494
hsa-miR-3074-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
DNAJC28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59578
HHIPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85888
cilium	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Serous carcinoma_Fallopian tube_GSE10971	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.11529
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04274
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
NCIH510	CCLE Cell Line Gene CNV Profiles	-1.0	-2.34714
TTLL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71007
SNTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99942
MEA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81546
preoptic alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06252
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.958877
Abducens nerve palsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.031
hsa-miR-548b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2264
mRNA_FOXP1_21924763	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.8203
NONO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79081
RNF17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63489
Perturb_14215_KO_Psen2_SRP254653	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.21386
r5 part of the oral Sp5 subnucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.96376
KMT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68155
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.86167
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-2.5382
Neuro-2a cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.204
PRPSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4474
PMC12229924-ab-24-0861-Supplementary-3.pdf-7-DMRT2_DMRT2	Rummagene Transcription Factor Associations 2026	1.0	null
FLYWCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67985
Intrinsic component of Golgi membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.572
metabolic syndrome x	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.15771
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043964
Septic Shock_Whole blood_GSE9692	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.44803
GSE205730,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67357
SNU-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.985317
KLE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72706
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A6K9-06A-41R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2913-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gallbladder	HPA Tissue Protein Expression Profiles	1.0	1.2595
GSE174701_4_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	83.6397
ATAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38839
SLC35C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08874
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.3069
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Autosomal recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.003
ODAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86476
Adult Gliosarcoma	DisGeNET Gene-Disease Associations	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7290-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal nervous system electrophysiology	MPO Gene-Phenotype Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5489-11A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66572
BHY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Tegmental reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0986
hsa-miR-548j	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
Perturb_15286_KO_Trp73_SRP067006	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-11.276
DMRTA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9695
Gfi1b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.5627
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13297
PTPRJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6743
NCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68897
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.944499
intermediate stratum of isBL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17412
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.049922
arteries	GAD Gene-Disease Associations	1.0	null
LOUNH91	DepMap CRISPR Gene Dependency	1.0	4.42491
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.94142
MEGF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71248
r9 portion of vagal motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15111
hsa-miR-1229	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
Posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56872
abnormal reflex	MPO Gene-Phenotype Associations	1.0	null
RET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66396
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1553
ELK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81101
MACROH2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45983
hsa-miR-4701-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GTF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90221
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSTA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3277
PTMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55457
LNZ308	CCLE Cell Line Gene Expression Profiles	1.0	3.38454
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4525
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53492
496100372_HIP_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.67749
KDM5A	ENCODE Transcription Factor Targets	1.0	null
medial amygdala, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15313
MAF-26560356-CHIP-SEQ-TH1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.71713
Paraventricular nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5412
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1192
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.80469
mesoderm	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.065898
GSE111247_14_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
OVOL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26763
MRPL14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26972
FANCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59459
intermediate stratum of r5Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16175
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.050555
CREB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9651
vascular disease	GWASdb SNP-Disease Associations	1.0	0.088236
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7646-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lek	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.87
PPDPF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03801
Lung adenocarcinoma_LUAD_TCGA-86-8076-01A-31R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G292CLONEA141B1	DepMap CRISPR Gene Dependency	1.0	3.06525
ZBTB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49129
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28597
PAQR6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41274
PPIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25457
BCAT-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
496100545_HIP_possible Alzheimer's disease_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.8253
BARX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.10814
GSE111247_11_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22714
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.91938
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.42908
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.165217
FIZZ2_KO_GDS4902_408_mouse_Lung	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SK-MEL-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nematocyst	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.85248
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.897238
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NMRAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7098
Ovarian Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
HCC1806	CCLE Cell Line Gene CNV Profiles	1.0	1.54268
septopallidal shell area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19643
WDR86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11219
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H1-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
AMO1	DepMap CRISPR Gene Dependency	1.0	3.12113
blood vessel	GTEx Tissue Gene Expression Profiles	-1.0	-1.23382
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
r1 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03205
TPRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19783
SFXN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78337
NDUFB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57415
KIF13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.91178
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04238
TSPOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52812
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.857177
EARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00867
KIFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91484
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
MAP4K5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3428
HNF4A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.515
CEP104	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13199
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.069924
Pancreatic adenocarcinoma_PAAD_TCGA-2L-AAQL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BL8876 (RIOK2)	NURSA Protein Complexes	1.0	null
SCG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09765
ZNF543	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.43003
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.24684
Bardet-Biedl Syndrome	DisGeNET Gene-Disease Associations	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.852802
hsa-miR-548a-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE195663_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FLI1::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.6853
ventrolateral part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02778
KP2	CCLE Cell Line Gene CNV Profiles	1.0	1.3426
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3066
anterior (rostral) cingulate (medial prefrontal) cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.895427
ASCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49338
CLN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.12741
Weight Loss	CTD Gene-Disease Associations	1.0	1.22371
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.394
POU5F1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0151
GATA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9073
SNU668	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51279
Overhydrated hereditary stomatocytosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.158
PRRC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81937
FRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88601