association	dataset	threshold value	standardized value
Sarcoplasmic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.742
ZNF679	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
NR3C2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0034
ZNF233	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84052
GON4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76766
DOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54633
PTER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75107
Glucose metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.057
ENDOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1668
PMC9387164-Table_2.XLSX-Sheet1-CLOCK_CLOCK	Rummagene Transcription Factor Associations 2026	1.0	null
RAVER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07952
CENPV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24541
Intercalated disc	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.781
CDR2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43382
FOXA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82811
FEV	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11824
EIF5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21474
FOXJ2::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2036
Hypertrophic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.264
Aortic valve disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
MSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2933
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1337
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.3491
USP38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78711
FOXO1::ELK3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1017
Prdm4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.2464
RALGPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61236
POU4F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.9715
FOXN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00076
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
BARHL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43048
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.1659
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1443
TOMM20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99927
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.3667
POLR2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23167
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0
TMEM179B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98841
MASP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70329
ST6GAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38403
GSE119978,GSE180930_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IFT80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53331
PAFAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82456
Pax7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0136
Roe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
ATAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38462
MRPS23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85444
LHFPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10727
HMGN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14204
SIX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.3481
SLC25A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76046
GAL3ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38584
CAPN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53962
TRIM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09558
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.138
FCHO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15277
Muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.785
PGF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54374
MST1R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13356
Skeletal muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.569
ABRAXAS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65552
FKBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57176
KDM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82467
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4151
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4256
CEP350	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95702
YIPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6571
MAPK15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74133
IP6K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61115
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0548
Saphenous vein endothelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
NOCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07674
IER5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66935
NAT8L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17838
USP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05165
GSE119978,GSE180930_2_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26903
SINHCAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77418
IDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55984
DENND5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0771
TNFRSF13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39368
APC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26958
TUBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13382
GSE158834_0_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12651
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5174
TACC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42344
DNMBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30004
TFEB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49438
SENP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1658
HOXA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91345
ACOT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32172
Timothy syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.056
Sarcoplasmic reticulum lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.642
C2CD2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51731
CLN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.12741
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.664
PRDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86061
Dlx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5931
RAD23B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77434
CAPN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39215
PCNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17653
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7815
Atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.673
MYO10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.096
RAB11FIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23234
KDM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37368
PRCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04454
MPC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03693
NVT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.72
ZNF793	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27345
NLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83655
DARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19175
CUX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8169
Uniplex complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.18
ZNF211	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9257
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3091
FLT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12507
DBP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.3679
AAMP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84187
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5959
PIK3C2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1175
TXNL4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34297
KDELR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53265
HENMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39744
JAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16874
PXDNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93826
MANF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4421
KLHL31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67319
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.4779
FKTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.2239
Malignant hyperthermia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
INSM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43945
NDUFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79888
GPR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37241
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	55.2628
PTGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30306
LRRC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23599
TGFBR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.91576
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5707
CERS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2097
ASB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28859
Sarcoplasmic reticulum	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
VAPB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3698
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SLC35F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6209
TBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7706
HOXB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4631
NODAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71059
SNCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25335
SLC25A52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9781
GSE164874_5_v_8_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0424
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.744
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CPHXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57806
GSE164874_5_v_4_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RBM48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22956
CHRNA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08401
CNOT9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64595
SIX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4458
UBA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51266
PLK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00114
GATA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5754
MRPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86232
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3849
KIF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11016
Extensor digitorum longus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.76
BARX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.5953
PRRG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82013
CHP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32481
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1024
PPM1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22435
ARHGEF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59209
Extensor	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.21
MGA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.404
Slow twitch muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.385
INSYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.50388
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.1563
ZNF142	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06652
ENO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08569
HHEX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27972
TBX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0711
MRPS35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90975
MYF5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.5545
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4915
SORT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45217
NR1D2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1072
UPF3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06883
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3043
ATXN7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44808
ZFYVE27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62777
IFITM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47364
DFFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03951
VAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7895
Arx	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6407
NID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80597
COX7A2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73731
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4594
Brody myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.141
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_11_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
EFNA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2899
ARGFX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73089
Keratosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
ELP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.04682
Taurine dioxygenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.079
ADIPOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78922
GMEB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9787
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4177
ACOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26849
GSE145915_3_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LETM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03235
EVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8845
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5299
sknf1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
PAPSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29065
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.395
ZKSCAN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54049
HABP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44053
GSE205316,GSE205317_0_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Atrophic muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.099
ZMYM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33856
IST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02184
Six4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.7952
MNX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4988
Leaflet of membrane bilayer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.788
IGFBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76162
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
PMC12696503-mmc2.xlsx-ST15_KD_RNA-seq_diff_expr-ensembl_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EMILIN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39102
ELMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47673
DPY19L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53082
SIPA1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24389
UTP14C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34626
POLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19987
Cardiac muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.033
PTPN23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45798
ISL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6839
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.1679
MAF::NFE2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9596
sarcoplasmic reticulum	GO Cellular Component Annotations 2025	1.0	null
DACH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19485
FABP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90457
C12orf43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51685
SPAG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05491
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.6973
FOXO1::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.9612
MYL12B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1574
KNOP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6446
WDR81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3039
ALX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60578
GNPDA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57553
GSE164874_5_v_9_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
ADISSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57564
PCGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77389
MUC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32634
PTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87933
DEGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16841
CHGB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34995
MANBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98959
GFER	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22652
Organelle subcompartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.27
CCDC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14621
S100A10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37387
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.908
GATA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7828
HAPLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96248
FOXG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.947
Arrhythmogenic right ventricular cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
PSME4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44241
Atrial fibrillation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.088
ALDH4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51346
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3985
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.9901
FOXO1::ELF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9284
RACK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.92807
PRKCG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54527
Pulmonary vein	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.703
GPX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52154
SAP18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6787
HARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20263
GSE102870_1_v_2_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF668	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65075
NFATC3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5896
GSE242555_1_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12466
STIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40785
GSE131649_6_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WWP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89614
CCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52076
EFNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84057
E2F6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41356
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68505
Congenital myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
CIITA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04756
SHISA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47705
NID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2043
TBX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1486
IL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21692
TBC1D10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70554
TMEM170A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4028
NR1H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46001
GSE158834_11_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
TBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5645
UBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40212
DMRTA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3812
ESYT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59523
GSE105406_0_v_3_ptcd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1505
Slow muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.463
Arid5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.8462
COQ9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43007
PIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66409
SEMA4F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96289
ACADSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11424
HEPH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55673
ATP2B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.23362
L3MBTL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71567
RBM15B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97336
DUSP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48641
T-REx 293 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.053
GSE233183,GSE233187_3_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1527
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0169
PDAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25968
DNMT3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.987
ACIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91029
TCF7L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0122
PFDN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86065
OTUD6B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96463
ZCCHC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48212
APTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87012
PMC12619835-41467_2025_66007_MOESM12_ESM.xlsx-KLF5_activated_H3K27ac_T3M4-Nearest_Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_2_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
NANOS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61707
GLI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61377
Saphenous vein endothelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
MPV17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51393
PPARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.25
GSE200897_1_v_0_pold1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30218
HOXB2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2605
ZMYM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67789
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.7717
NDUFB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42489
Sox1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.7557
NES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40166
Pou5f1::Sox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.9165
SLC39A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.84396
SQSTM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.21527
FUZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14123
ZNF511	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66951
TMEM242	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44344
Yy1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.158
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9923
Sarcoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4169
GSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2959
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1891
MTMR9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29463
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.6826
Congenital myopathy 1A	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.095
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.973
ZFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93053
ACTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23436
Bounding membrane of organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.19
TTC30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27043
Muscle tissue disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.672
NR2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.7102
PMC6167382-41467_2018_6258_MOESM4_ESM.xlsx-TEAD-associated_GSC-Specific_UP-Nearest_Ensembl_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
Endoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.325
GSE242555_1_v_0_fn3k_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4543
sarcoplasmic reticulum membrane	GO Cellular Component Annotations 2025	1.0	null
ETV2::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2884
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.5879
MED28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69324
SPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26462
COL4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8447
STMN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91713
RRP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32243
CDC25B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66565
ASCL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.49338
CTNNA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30397
H2AC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25071
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9037
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.8156
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.9077
NHEJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45148
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	77.3152
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7283
IFI6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23465
SPCS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7594
PIWIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84481
ankyrin-B-related cardiac arrhythmia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.27
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3352
ARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82131
Heart conduction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
Forestomach	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.701
LYPLA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47815
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2109
RTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91968
GSE195559_6_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	60.1819
ARCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59341
AVPI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80393
Endoplasmic reticulum subcompartment	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.323
Striated muscle cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.5
MAPRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47542
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4311
DPYSL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33538
BACH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.2896
ARHGEF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48697
SEMA4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10583
MMS22L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25164
PHACTR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21803
HTRA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35386
RUNX1T1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82772
MAP3K9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62736
Gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
CFAP97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25368
TEX264	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18547
Organelle subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
NKX6-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9496
TMEM127	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75062
GSE129811_5_v_0_niacin_human	RummaGEO Drug Perturbation Signatures	1.0	null
regulation of calcium ion transmembrane transporter activity	GO Biological Process Annotations 2025	1.0	null
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.9337
regulation of slow-twitch skeletal muscle fiber contraction	GO Biological Process Annotations 2025	1.0	null
ARMCX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22077
SOX8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8585
USP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.06386
PEG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40482
UBE2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3684
PPIF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.03001
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	72.4856
LSM14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95933
Mitochondrial pyruvate dehydrogenase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.592
MYRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38694
TBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30827
C5orf24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33459
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.656
ZNF136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38258
ENTPD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46569
SKIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08281
TRIM16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01786
Fast twitch muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.845
Phospholamban complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.887
ZSCAN5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2354
DENND10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97604
RPRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93819
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-ENSEMBL_ID_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
Cardiac Troponin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.913
BAZ2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73589
ARMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67096
GSE143782_6_v_5_calcitriol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAFK	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5607
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7669
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARHGAP11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50784
SRSF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11042
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9151
ZSWIM9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05762
Myocardial infarction	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.511
GSE236228_0_v_1_penfluridol_human	RummaGEO Drug Perturbation Signatures	1.0	null
SRY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5357
Dux	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.8722
MAPK14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51023
CUX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.739
XRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65371
ADCK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8061
SPOUT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38274
COL5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76874
MPZL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33663
Gluteal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.079
Shox2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.1113
CLTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.61321
BSX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1614
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.9311
ARRDC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69579
KIF1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24426
MAF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5697
SMARCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35456
CTNNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31654
DDX49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57867
PMC12774775-mmc2.xlsx-PAR_RARG_merge_q5_Narrow_subKO-Gene_Symbol_RARG	Rummagene Transcription Factor Associations 2026	1.0	null
C8orf82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35718
Keratosis follicularis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.777
MAP2K7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95595
Vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.4605
MSI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.178
Eht	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.542
TRPS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3472
GPBP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64898
Carbohydrate metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.064
APLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76981
HOXA7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.9765
CRNKL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81045
ZNF66	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00305
MRPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6369
AJUBA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.21569
NUTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23342
SHOC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94487
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3579
USP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64226
ZNF566	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48042
BOD1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65882
MTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00438
GEMIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7697
NACA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47383
SESTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80054
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.2283
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF738	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74262
TAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08256
ZFP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72907
PPP1R8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23604
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.6241
SOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5679
ENPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30859
Msx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4625
GSE205316,GSE205317_2_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GLT8D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00416
OFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30376
ZNF853	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.47111
PNLDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26141
ATP13A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72391
CDR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14686
Diabetes mellitus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
COA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39842
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1807
EIF3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12489
MAP3K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00439
FOXC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4931
TRAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12982
RUBCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21524
NOL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30134
RPAIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53795
FAM229B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.70092
MAGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67604
Coronary artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.474
TLE4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75349
GNPTAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51666
Musculoskeletal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.262
R3HDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68173
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1782
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.1436
SRP54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21008
KLF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27464
TRUB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44171
ZNF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93941
ZNF384	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20175
Sinus node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.648
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5827
SHOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01083
Paraspeckles	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.79
FOXD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4
CEP43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43455
B3GAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11799
SCRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25042
KLHDC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75304
Nuclear membrane microtubule tethering complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.109
TMEM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61246
ARHGAP19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82534
ZFP62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10231
METTL27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07377
PTPN14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36695
Aortic adventitial fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
X-linked recessive disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.42
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7882
PDLIM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11498
TSPAN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97914
ATF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41296
KDM1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37442
TPD52L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06997
Fast muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.038
GSE119978,GSE180930_6_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE88819_11_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Soleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.633
SOX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5706
MDH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.10535
PRELID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08686
TXNRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57442
Sarcoplasmic reticulum membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.911
ACER3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17821
F8A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79005
C10orf105	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30867
C17orf97	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33212
HNRNPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29038
COIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21969
SEC61B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02483
SLC37A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34555
EMC9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59131
ADAMTS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47517
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF157	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.5317
PMC9174176-41467_2022_30924_MOESM6_ESM.xlsx-OC2-SYMBOL_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
Endoplasmic reticulum protein-containing complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.317
PLCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18119
PKIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45742
ZNF207	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25239
Thap11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	27.1848
PALM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17928
PANO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81654
PCNX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41109
GIGYF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41535
regulation of ATPase-coupled calcium transmembrane transporter activity	GO Biological Process Annotations 2025	1.0	null
H1-6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17819
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.8354
SLFN13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71959
ZNF781	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87941
GSE100732,GSE100733_0_v_1_lrpprc_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PELI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72011
PDHX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02395
Muscle fibre	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.939
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.0517
NUP42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60224
PRXL2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39772
DUXA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.1447
NKX1-1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27372
MDFI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97479
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.1111
CASTOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17335
ANKRD54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69776
UACC-812 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.997
VPS33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4412
UNC119B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85074
MAST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37231
Protein phosphatase inhibitor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.872
positive regulation of calcium ion import into sarcoplasmic reticulum	GO Biological Process Annotations 2025	1.0	null
ERFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41828
ZSCAN22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41334
HEY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71858
ZNF680	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5737
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43024
DLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3588
RMI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28648
KEAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08859
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Alx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.5894
TMEM230	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02562
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
ANKRD52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45422
ZNF35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.9012
RCOR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85339
HECTD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89456
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GALT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62708
NDUFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48778
MRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37619
CHAF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21182
Aortic valve stenosis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.115
Nuclear outer membrane-endoplasmic reticulum membrane network	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.322
SCMH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01781
ZNF844	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56213
VENTX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.714
TEF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.0917
PADI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20511
ATOH7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4898
PABPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81414
Long QT syndrome 8	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.183
Dilated cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.092
GSE217156_2_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXC8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5833
CNTRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85191
RGMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33945
RDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59999
POLR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17547
CNOT6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40383
Cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.939
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6817
FOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09403
CHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32248
Endoplasmic reticulum membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ITGA2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31226
GPR180	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44746
MAFG::NFE2L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2747
HCN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12832
Meiotic nuclear membrane microtubule tethering complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.109
IFT57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34952
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0608
AIMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14429
NASP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33906
FGD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80797
PRICKLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31379
POU3F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.0695
Nuclear outer membrane-endoplasmic reticulum membrane network	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ACOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46338
MRFAP1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18813
LMBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23871
TRIM56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39516
ERF::FOXO1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9759
POM121	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00111
PSMA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1513
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.4153
Myotome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.629
IL17RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34198
DHX38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31003
STON1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13697
ELK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81101
C17orf58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39327
ACTN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90997
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.2233
IFT52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32121
GORASP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.89174
TMEM186	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29394
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0679
Muscular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.617
bounding membrane of organelle	GO Cellular Component Annotations 2025	1.0	null
DRG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22621
MTSS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98305
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0329
PMC12520974-44161_2025_709_MOESM2_ESM.xlsx-Extended_Data_Fig_4a-Extended_Data_Fig_4a_Marker_genes_used_in_the_heatmap_for_ATF3_4_Capillary_and_Venous_in_non-ischemic_vs_PAD_comparison_ATF3	Rummagene Transcription Factor Associations 2026	1.0	null
Skeletal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.069
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0001
Hoxd13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9527
CXCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44312
HNRNPU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07198
PGLYRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24902
GSE183335,GSE183351_3_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2939
M6PR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28552
TRIB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36644
ZNF883	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80917
GSE198036,GSE198041_4_v_3_sox9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MSRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60459
SNAP29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05201
OPLAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65888
Diaphragm	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.343
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4411
SSR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78645
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7326
UBE2J1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12377
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
S100A16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94671
positive regulation of calcium ion transport	GO Biological Process Annotations 2025	1.0	null
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7658
ZNF662	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54819
RPS9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1491
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1971
HSPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27762
MYOZ3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3112
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
MTX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5489
SOX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73484
IRF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22513
Plantaris muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.028
GSE158834_11_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE119978,GSE180930_6_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CYP27B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50567
Nuclear membrane protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.083
BARX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7789
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.7946
CD40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49655
Endoplasmic reticulum subcompartment	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
STAT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94546
SOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22567
X-linked monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.373
SKIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44809
PCDHB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92823
SFMBT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.6442
CACFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76156
RUNX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56995
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0308
TAF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19549
PMC12019336-41467_2025_58868_MOESM5_ESM.xlsx-Open_peaks_IKAROS_WT-Unnamed_5_IKZF1	Rummagene Transcription Factor Associations 2026	1.0	null
SEMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31538
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
GRPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51217
PTPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14639
GABRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02719
ZNF837	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56669
ZNF26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56684
RAB11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13226
RAB11FIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08574
BMAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31224
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.098
AP1AR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92057
TULP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82786
Myopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.677
HOXA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24202
Intrinsic cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.038
XPO5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06451
DYNC1LI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85904
KIAA1143	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43794
HOXA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40803
NR2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.4829
L3HYPDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31547
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Polysome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.3
RHOXF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4709
GSE152055_0_v_1_mpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cAMP-dependent protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.792
GSE205316,GSE205317_0_v_3_nrip1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TLX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4253
PDIA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57533
MAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05567
ARPC5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00981
PIERCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16973
MAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34179
HAND2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39704
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	97.6199
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0816
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4409
Amylin receptor complex 2	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.907
ADGRL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71826
Catecholaminergic polymorphic ventricular tachycardia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.22
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2862
KDM6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61174
CFAP126	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90657
ATP5PF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46193
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2164
Artery disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.334
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.0494
FOXB1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3573
CHCHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37927
Dlx4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9038
RAPGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77738
TPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26852
ZNF563	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31734
PDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36425
GSE158834_0_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
AVL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15831
KIAA2026	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89814
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.066
BAG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0622
SCG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67403
regulation of twitch skeletal muscle contraction	GO Biological Process Annotations 2025	1.0	null
UQCR10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57224
GSE131649_6_v_1_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HMCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19971
DEAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09483
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.7825
AIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9415
SLC22A17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83465
SH3GL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.0975
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.26
DROSHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90776
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.0428
TMTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07501
POU3F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.8826
GSE173394_1_v_0_nfatc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZIM3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.3315
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.6
PDPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70734
RP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1202
DCAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58576
NR1D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81774
CYB561A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48322
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.618
GUF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54725
FOXB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49058
PSME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49898
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4818
MDP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76759
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.598
SIGLEC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22423
CKM complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.78
KLF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21444
OTUD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31004
NKTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3035
POU5F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3565
EGR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16201
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0197
GC-1 spg cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.594
LBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.4648
DBF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11854
KCNA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0809
PPP1R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83196
SNX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88386
CILP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68263
PRPSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4474
LYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29617
RPS4Y1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40822
WDR48	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62608
HOXD8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.665
ETV5::FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3884
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6818
AK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66725
CLDN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66389
HSPA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32633
GSE60691_2_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF280B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65987
Reticulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.807
DYNC1LI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19688
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7107
KIF14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05257
ZFP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27195
GSE88819_6_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.5345
GSE164874_5_v_3_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5961
FOSL2::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.0711
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8322
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
API5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57187
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	63.3633
CSTF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69405
Microtubule organizing center attachment site	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.063
LSM12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55621
GSE148262,GSE150691_3_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OLIG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.5304
RBM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08701
POU4F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9317
GSE211955_1_v_0_jmjd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3026
ODC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34512
ANKRD30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35754
GPAT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59735
Arid3a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.0
RAD50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16394
BHLHE23	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.6348
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8082
TNRC6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22434
MGAT4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09023
AUP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96111
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0707
CKAP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28762
EPN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20951
CCDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38379
GSE223241_1_v_3_cdkn2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL1::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1017
GSE136340_3_v_4_darunavir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SURF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59397
CDCA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50633
STAC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32101
Cardiac Purkinje fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.56
BLTP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40252
ESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2614
FGF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45021
CCDC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58017
SMG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12404
Lhx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	44.8
PLEKHA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55012
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.2762
DLX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66196
Cardiac muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.902
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4382
MRPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77974
SNRPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3201
positive regulation of intracellular transport	GO Biological Process Annotations 2025	1.0	null
EPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99321
KYAT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30474
PHOX2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55016
MPLKIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.94046
GCDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97717
UBN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23788
CREB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25618
PAQR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23117
ZNF727	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06846
TAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44733
NKG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62527
EN2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.2366
EIF4G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02295
BCAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37456
ZNF569	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39354
FAM174C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46042
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.6391
VPS37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35111
ACSBG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.99536
Hmga1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	49.0937
METRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33216
MRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63443
ACTR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51934
SMCO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70044
ECE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62606
regulation of calcium ion import into sarcoplasmic reticulum	GO Biological Process Annotations 2025	1.0	null
KLK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26576
CD74	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36201
HOXD8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52224
ERBB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5018
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.2407
Thorax muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.395
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.479
CYB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49036
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.3952
PITPNC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.887
VENTX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32607
NUFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35494
TBX15	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.0266
ZC3H12A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26965
IFI16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87871
Body wall muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.884
lm9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.481
EMX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9615
NSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53909
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Inherited metabolic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
LAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81695
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9202
PNPO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02564
NR2C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2653
FOXD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07496
RPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19128
ISX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3223
ESD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26344
ADAMTS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.83396
PRMT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66408
MRPS34	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27715
c87	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.367
endoplasmic reticulum membrane	GO Cellular Component Annotations 2025	1.0	null
Sarcoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
POU4F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	51.3724
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.5236
VCX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50396
IL11RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52129
UBE2H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54549
PCDHB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70809
H4C13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59712
RTBDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41829
GSE234289_4_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	1.0	null
CIART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46144
UBXN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17196
Duchenne muscular dystrophy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.671
RGS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.77238
chr3_155297083_G_C_b38	GTEx eQTL 2025	1.0	2.68881
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71087
UQCRFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32231
DNAJC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46276
HMGN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54632
ATAD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45098
ZNF260	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67873
ADPGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63617
AMIGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45537
PDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.6133
CCDC107	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.11529
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6636
GCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92297
SNTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99942
RNASE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95184
ERCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67397
NOXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89008
SRSF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14719
SLC36A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52012
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.5422
MRPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54822
NEFH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44261
Sarcoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.689
GSE77795_2_v_1_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7772
LHX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1284
CD2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59837
ZNF382	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.1766
NADK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17768
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9388
HACL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30561
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.24
GALNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36324
VAT1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85994
Leg muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.515
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0464
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7134
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7671
FOXP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.00362
S100A13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80977
CHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06247
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1515
SMIM24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04497
ACAA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56512
LSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15465
Sarcolemma	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.309
NKAIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34761
ZNF746	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15254
POLL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28495
Twitch muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.637