association	dataset	threshold value	standardized value
UNC45A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62199
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.860208
GTPBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31355
15374961-TableS2	GeneSigDB Published Gene Signatures	1.0	null
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.06839
hsa-miR-3972	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
DNASE1L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56096
H-NS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.845
Excitatory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.232
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13907
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48425
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.858104
oculomotor nuclear complex, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.907935
Uremia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.075
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18546
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02475
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A497-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99894
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210476_11_v_5_rutaecarpine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.17104
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.123138
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DOC2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81097
RIGI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.11081
synaptic vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
POGK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17246
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898412
GSE214382,GSE214383_4_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F1-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE216273,GSE216292_14_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GALNS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23769
INSM1_KO_GDS5066_472_mouse_pituitary gland	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979935
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
KYSE410	CCLE Cell Line Gene CNV Profiles	1.0	1.74726
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899421
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28697
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6K1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreas-pancreatic beta cell	Tabula Sapiens Gene-Cell Associations	1.0	1.24226
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00448
ERLEC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57431
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DPP3_OE_GDS2653_650_human_IMR-32 neuroblastoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
hsa-miR-10b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PRODH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.3307
SPAST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85933
GLI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62711
GSE205163,GSE205164_1_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	1.0	null
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.34166
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF277	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36372
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25328
Lung squamous cell carcinoma_LUSC_TCGA-18-3410-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE67266_7_v_3_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49558
Early onset absence epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.11
NDUFB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57415
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.95033
PMC8554124-DataSheet2.XLSX-57-CEBPD_CEBPD	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87248
SMYD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31194
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Peripheral Nervous System Diseases	CTD Gene-Disease Associations	1.0	2.88009
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15705
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13303
R3HDM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68173
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149035_1_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	1.0	null
HNRNPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45877
Kidney renal papillary cell carcinoma_KIRP_TCGA-J7-8537-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.987955
EGR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
REST_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4A	ChEA Transcription Factor Targets	1.0	null
TMEM81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05968
REST_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATP6AP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64522
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adrenal gland cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.183235
DDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.97657
PHLDA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21569
IFRD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.07319
Synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Skeletal Muscle Female	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.890917
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.346
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CPSF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39563
SMIM26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26325
FN3K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64767
TP53-20018659-R1E-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4469	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
CPOX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81619
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3450-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SFT2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83546
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05352
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89066
GSE207302,GSE207303_0_v_2_tp53bp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
VEZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7305
MED14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73641
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.08465
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
MFAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01212
KDM5A	ENCODE Transcription Factor Targets	1.0	null
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.358
PANK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36284
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46161
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FDXACB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2886
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4859-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE154767_1_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NIPSNAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96275
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07076
neurula	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.06779
AKIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7062
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AGAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53959
Neurosecretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.663
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.99159
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53648
BBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13045
IBTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52878
Perturb_5169_KO_Ddx5_SRP068412	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.47193
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.03305
ILKAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74303
MACROH2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45983
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.87955
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.887757
JUN	ENCODE Transcription Factor Targets	1.0	null
ZNF501	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56112
hippocampus (hippocampal formation)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.874653
TEAD4_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.584686
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1124
FARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87493
MFGE8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50723
LRIG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11967
GTEX-XOTO-0011-R11B-SM-4B64O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08697
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.995001
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IQGAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46925
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14726
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ASPHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43628
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1323
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20651
hsa-miR-1224-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE148252_5_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
inferior frontal gyrus, opercular part, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.995137
ELAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13599
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.969911
TTF2-22483619-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
POLR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7009
SH10TC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47411
DMRTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22626
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01767
Electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.019
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
SMURF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91543
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TTF2-22483619-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CHP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32481
GTEX-S7SE-2526-SM-2XCDL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17431
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02363
GSE94814_1_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Botulism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
General substrate transporter	InterPro Predicted Protein Domain Annotations	1.0	null
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.74985
PSMG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1112
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911499
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8196
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9514
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.53087
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
ENTPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.08156
cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TC71	CCLE Cell Line Gene CNV Profiles	1.0	1.90102
TET1	ChEA Transcription Factor Targets	1.0	null
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ALG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97493
PHF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03024
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.049406
KLHL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41525
cell part	GO Cellular Component Annotations 2015	1.0	null
GSE210101,GSE210114_5_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DMS53	CCLE Cell Line Gene CNV Profiles	1.0	1.35864
ARMCX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78183
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
frontal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.965796
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C1orf52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51266
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-767-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-2926-SM-4B65G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0989
cellular_component	GO Cellular Component Annotations 2015	1.0	null
substrate-specific transporter activity	GO Molecular Function Annotations 2015	1.0	null
GSE211177,GSE211178_9_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14446
PMC12670081-mct-24-0704_supplementary_table_s10_suppst10.xlsx-Supplementary_Table_S10-Supplementary_Table_S10_Differential_expression_of_TFCP2-rearranged_RMS_Vs_Other_RMS_FC_3_padj_0_01_TFCP2	Rummagene Transcription Factor Associations 2026	1.0	null
CSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01652
CAOV3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44514
hsa-miR-1470	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043606
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27207
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SERF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37184
NR5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67849
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE244518,GSE244520_1_v_0_dnmt3b_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF263	ENCODE Transcription Factor Targets	1.0	null
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940604
PRDX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31743
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TNKS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53593
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7061-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TDGF1P3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43579
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
ADAMTS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01367
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
ZCCHC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77646
USP21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30845
MDAMB231	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.862175
TP53-20018659-R1E-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23114
GSE100102_0_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EFCAB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.00577
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
uremia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.701526
GNG12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.54183
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-RS-A6TO-01A-32R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-3.27518
UTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67743
AK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40993
TMEM130	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50525
MITF	ChEA Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-3771-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MDAMB134VI	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	2.40471
SW1271	CCLE Cell Line Gene Expression Profiles	-1.0	-2.08946
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DHRS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24291
PBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73047
stratum pyramidale of caudal CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.858983
primary visual cortex (striate cortex, area V1/17)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.827662
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
SF-767 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.023
TPRG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21875
SEC11C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15685
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.88193
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ISCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24109
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BBS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72138
GPR137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85382
Acute Myeloid Leukemia_LAML_TCGA-AB-2941-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-DX-A7EM-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.26414
SRF	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MECOM_KO_GDS3343_554_mouse_Hematopoietic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE210101,GSE210114_2_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876624
KE97	CCLE Cell Line Gene CNV Profiles	1.0	1.42241
hsa-miR-4800-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
HUPT3	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
NCIH716	CCLE Cell Line Gene Expression Profiles	1.0	2.25264
ONS76	CCLE Cell Line Gene Expression Profiles	-1.0	-1.75522
HDAC2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3194-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Perturb_4321_KD_Cck_SRP220728	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.15072
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19879
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23083
TMEM187	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8381
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922657
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PLAU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80031
GSE133683_3_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DERL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19376
ERBB2_knockdown_231_GSE8373	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.77977
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE211931_2_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in dorsomedial extrastriate cortex (V2)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.3843
PEX11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72484
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.464798
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24543
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980723
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE151119_3_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58331
KRT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40015
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01631
increased mean corpuscular hemoglobin concentration	MGI Mouse Phenotype Associations 2023	1.0	null
AHDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73785
GTEX-XLM4-2926-SM-4AT59	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947163
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
bleomycin_mus musculus_gpl6885_gse37635	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PEA15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67979
tongueepidermis	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.990271
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ETV5_01_304	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60351
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Synaptic vesicle, resting pool	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.691
DLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7856
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7133
Perturb_2176_KO_Nlrp3_SRP366634	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.7668
FOXP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26343
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4897
SEPTIN7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22873
ANKFY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74456
hsa-miR-502-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GSE203308_6_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SREBF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8847
GSE144231_6_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PDZD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27929
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941743
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE131887_5_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE234289_5_v_0_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.299452
dentate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.841291
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTF2H5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76924
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064207
Transport vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
MRPL47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5837
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
CALM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28035
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911395
TMEM74B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7395
CCDC137	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14649
SNTA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44434
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ASPM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53386
TIA1_KO_GSE54418_266_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.922319
pheochromocytoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.187122
GSE238116_1_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08751
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042118
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7091-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IF-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09874
RANGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.46088
D341MED	CCLE Cell Line Gene Expression Profiles	1.0	1.75104
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FB-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G6PC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33403
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05123
SKBR3	CCLE Cell Line Gene CNV Profiles	-1.0	-2.97303
H3K27ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TAF15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37804
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EFNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03461
INSM1_lack of the seven N-terminal amino acids_GDS5066_404_mouse_pituitary glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
IKZF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44673
telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.34814
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF213	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13466
MRPS17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87542
AN3CA	CCLE Cell Line Gene Expression Profiles	-1.0	-3.10204
Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868084
GSE238116_3_v_2_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE162087_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
estradiol_mus musculus_gpl4134_gse23072	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Toll-like receptor 2-Toll-like receptor 6 protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.883
NIPBL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70421
SIN3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC2A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9788
ADCY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70764
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE121809_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRICKLE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62038
Spine synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.931
COL7A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50099
GSTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87093
JUND	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54632
cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921473
retina	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.836177
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11661
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5679-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EBC1	CCLE Cell Line Gene CNV Profiles	1.0	2.06793
MYC	ENCODE Transcription Factor Targets	1.0	null
NKAPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29678
Kidney renal papillary cell carcinoma_KIRP_TCGA-2Z-A9J5-01A-21R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58128
SOX11	ChEA Transcription Factor Targets	1.0	null
transmembrane transport	GO Biological Process Annotations 2015	1.0	null
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal gait	IMPC Knockout Mouse Phenotypes	1.0	null
GSE216273,GSE216292_14_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARHGEF10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71628
A204	CCLE Cell Line Gene Expression Profiles	-1.0	-1.91235
smarcc2_00000000_e12dot5_embryonic_cortex_lof_mouse_gpl6887_gse45629	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.225632
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81N-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
GSE95077_5_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Presynapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.27914
REST_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5696-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4858-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55643
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35152
GSE221577_4_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Dendritic filopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.927
FN3KRP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43573
NFIA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85895
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175571_3_v_2_acsl6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ALX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97056
PGBD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36273
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31819
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.406
SP4	ENCODE Transcription Factor Targets	1.0	null
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SIMA	CCLE Cell Line Gene Expression Profiles	1.0	1.5775
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF695	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67286
HS571T	CCLE Cell Line Gene Expression Profiles	-1.0	-2.07529
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE93674_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MED12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1988
GSE210770_0_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900033
Sarcoma_SARC_TCGA-DX-A6B9-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
KHK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44642
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924866
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.23708
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNAPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16118
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4735-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB11FIP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01014
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.8519
Synaptic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
PABPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21547
SLC12A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6073
GTEX-WHSE-0011-R11A-SM-3P5YY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0317
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
PTPRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54573
WDR35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33564
emboliform nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28796
ATP6V0E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05763
TEAD4	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949625
DELE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83602
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.244
Peritoneal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.893
AUTS2-25519132-293T-REX-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-4483	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
USP51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.585
DAB2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52695
Dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.07
LEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28443
H3K27me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF2BPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09493
YDJC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2559
CAPAN2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.68196
JVM3	CCLE Cell Line Gene CNV Profiles	1.0	1.54647
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054632
FOXI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41143
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE244940_0_v_1_edf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Q2AG-0011-R11A-SM-2HMKZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32325
GTEX-UTHO-2926-SM-3P5Z9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08726
PYROXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52218
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2-23942234-MYOBLASTS AND MYOTUBES-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE186647,GSE217288_2_v_4_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66454
GSE70499_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881743
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
medial orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.825003
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.864491
GSE202603_0_v_2_bhlhe40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FAM89B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7983
INSM1_Deficiency_GDS5066_272_mouse_Fetal pituitary glands from embryonic day 17.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TNFAIP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40982
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MAML3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24835
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927579
fallopian tube	GTEx Tissue Gene Expression Profiles	-1.0	-2.10021
DDX3X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86359
impaired righting response	IMPC Knockout Mouse Phenotypes	1.0	null
FERMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45007
CYYR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.18977
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.984429
OIP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.17955
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.959731
ISG20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61431
Perturb_196_KD_Mapk7_SRP110236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.73534
SLFN5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22435
AP4B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83632
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35598
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01541
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TNNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13726
hsa-miR-4668-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.544
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01955
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854964
GSE87615_2_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
OSR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4636
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.00299
GSE151119_3_v_1_hsf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MSANTD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2166
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06836
KCNQ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40428
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.01941
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938226
hippocampus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.07371
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2159
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39819
kidney failure	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.174354
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE68156_0_v_1_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.849448
KLHL17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57104
MAZ	ENCODE Transcription Factor Targets	1.0	null
GSE236454,GSE236456_0_v_1_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044472
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JD-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145249_0_v_3_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE126127_5_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_MSC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.05174
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.861036
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-toNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
MDAMB231	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69146
Perturb_5339_KO_Tnfaip2_SRP256539	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
FAF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27296
GSE205163,GSE205164_2_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
PPARG	ChEA Transcription Factor Targets	1.0	null
ZNF652	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6609
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKNFI	CCLE Cell Line Gene Expression Profiles	1.0	1.50693
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GNAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20104
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.75537
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
H3K27me3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
H3K27me3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reticular nucleus of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16501
COL27A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97242
MRPL51	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93358
GSE122067_3_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.15849
496100438_PCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24658
disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043929
OVOL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41461
PROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26903
Toll-like receptor 1-Toll-like receptor 2 protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.79
TP53-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CDCA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39502
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A4BA-01A-21R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AASS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4093
mRNA_POU5F1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.92646
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.889534
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1107
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
DAAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87991
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.87457
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.961663
DPM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65991
SRF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.78731
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04323
PIANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17717
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984555
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.45
PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4051124-1471-2164-15-256-S16.XLSX-WES_IPD-RBCK1_2-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.93537
Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-7841-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-2926-SM-2TF66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12456
TRIM54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.7385
PARP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.61415
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE128333_3_v_0_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-N7MS-0011-R11A-SM-2HMJS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35476
MOLP2	CCLE Cell Line Gene Expression Profiles	1.0	2.50572
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lateral tuberal nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66737
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.980916
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61218
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.11598
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.98083
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RSPRY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65604
TBX20-22328084-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ST6GAL1_Deficiency_GDS3151_608_mouse_Mammary tumors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937768
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZR75B	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.885883
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053677
NUP133	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35876
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.944649
adrenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.145734
NNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27544
SUZ12	ENCODE Transcription Factor Targets	1.0	null
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.943842
SRF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CNEP1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6736
PRSS27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07224
CDK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96296
Presynaptic periactive zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.073
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.076997
DRD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72037
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
GSE128054_1_v_0_myt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	2.05704
HDAC3_KO_GDS4886_66_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Perturb_12544_KO_Ctnnb1_SRP194249	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.5388
Infant botulism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
inner SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.912501
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03823
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17916
WT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2081
HDHD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64611
TEAD4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2109
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041218
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910111
REST_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54628
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6485
hsa-miR-449a	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
PMC9541747-AGE-53-680-s003.xlsx-TableS6-Table_S6_Genes_with_missense_mutations_in_Yaroslavl_cattle_MAF_0_1_and_FST_0_4_in_the_1000_Bull_Genomes_Run_9_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DAGLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70395
GSE148252_7_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48963
Secretory vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACBD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73878
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039232
SPI1	ENCODE Transcription Factor Targets	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
HFM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70783
GSE227891_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
epithalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.547724
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921573
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14265
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.24722
TCF21-26020271-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
WDR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11898
PPIG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05138
Perturb_9042_KO_UTX/JMJD3_SRP158713	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
mRNA_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04504
ZNF33A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19421
cuneate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.973184
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
AK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20108
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.77995
GTEX-WVLH-2926-SM-3MJG5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12994
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0713
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE203308_9_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RASA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94826
SKM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9192
HCC1395	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58171
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PARP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52428
ZNF524	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.08161
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7587013-GLIA-68-2613-s005.xlsx-ASCL1_Putative_Targets-Overlapping_Genes_ChIP-seq_8791_ASCL1_Assoc_Genes_vs_TCGA_RNA-seq_2136_Top_10_ASCL1-positively_Correlated_Genes_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907625
RARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41922
LDOC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32933
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37835
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZSCAN29	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55456
SRF	ENCODE Transcription Factor Targets	1.0	null
GTEX-N7MS-0011-R2a-SM-2HML6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.964187
UBA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95242
cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051241
KDM5B	ENCODE Transcription Factor Targets	1.0	null
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07216
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864033
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02985
QSOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.39351
fallopian tube	HPA Tissue Protein Expression Profiles	-1.0	-0.770588
INO80E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97589
UACC257	CCLE Cell Line Gene CNV Profiles	1.0	2.12953
GLIPR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.69777
primary motor cortex (area M1, area 4)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30135
urinarybladder_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.953176
CREB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25618
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239373_0_v_1_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SLC35A5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.06045
UBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90909
BRMS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11458
synapse part	GO Cellular Component Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A63U-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL6-25482012-CML-JURL-MK1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE153836_14_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CCFSTTG1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.63979
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4436
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.49331
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70804
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53411
PITHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5925
GTEX-RU72-0011-R11A-SM-2TF6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16805
GSE88819_1_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PADI4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40118
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
peritoneal dialysis fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.25101
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7048-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834401
H3K4me1_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SLC7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26312
SOX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5078
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.98162
GSE190316,GSE190324_6_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Organic cation transport protein	InterPro Predicted Protein Domain Annotations	1.0	null
CITED2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83506
ACCMESO1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.53107
APOD_OE_GDS3913_489_mouse_Cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE88819_1_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
XPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09316
JUND	ENCODE Transcription Factor Targets	1.0	null
CALML6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33064
Ejaculatory duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.509
REST_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Calyx of Held	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.131
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.848169
posteroventral (inferior) parietal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17385
EDC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67639
VRK1_knockout_64_GSE19329	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.18005
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pc-12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.315498
cytoplasmic vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
ACTR3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.57518
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PCDHB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2615
UBE2Z	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8093
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.899329
TEN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49707
Necrosis	CTD Gene-Disease Associations	1.0	1.1437
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
increased mean corpuscular hemoglobin	MGI Mouse Phenotype Associations 2023	1.0	null
GSE136742,GSE136744_0_v_3_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876743
GTEX-WL46-2826-SM-3LK81	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31746
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.14604
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053793
Connective tissue	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
RWDD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79322
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12052
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1	ChEA Transcription Factor Targets	1.0	null
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
PAK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13253
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216043_11_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ALKBH8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10453
integral component of synaptic vesicle membrane	SynGO Synaptic Gene Annotations	1.0	null
CYP20A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.96382
ZNF598	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40169
TET1-21451524-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4701-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2-23942234-MYOBLASTS-AND-MYOTUBES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PWO3-1026-SM-2I5F2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993471
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35583
TMEM256	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7303
CDC23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33626
TWSG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36512
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_3_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventricular (matrix) zone of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50144
H3K9me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ATP5MC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88087
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.096845
localization	GO Biological Process Annotations 2015	1.0	null
GSE195743_3_v_2_lhx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QVJO-1325-SM-2S1QX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982804
TIA1_KO_GSE54418_265_mouse_midbrain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cervix, uterine	HPA Tissue Protein Expression Profiles	-1.0	-0.770588
Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE212312_1_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	1.0	null
USP49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2665
GSE216043_11_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
DDX27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51667
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE149096_4_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TUBB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17893
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ERBB3_knockout_239_GSE32129	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	0.750908
496100416_FWM_dementia_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05793
ZNF341	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1676
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36917
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841578
SKMM2	CCLE Cell Line Gene Expression Profiles	1.0	1.85242
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POU6F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64516
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52582
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
VPS4A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02408
EYA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91784
Bacteriocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.687
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02363
GSE179002_0_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_4823_KD_Chd4_SRP315519	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.29345
ATAD3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47611
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE221327_8_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05123
GSE148252_5_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98339
Transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.266
RBPJ-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
GSE182680,GSE182683_0_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
LAMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.80717
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Venom apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.935
SDAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28705
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57882
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931681
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47457
FOXA1	JASPAR Predicted Transcription Factor Targets	1.0	null
RNASE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33372
SPOP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61849
GSE210377_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF350	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01598
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01695
CFAP36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3485
SMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30763
GSE133213_6_v_3_znrf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BLOC-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.642
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21095
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.178299
Pleated septate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.025
UBE2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.48559
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984328
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949444
PAFAH1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72197
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47726
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.664
SRF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JARID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13883
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Secretory vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.058
GSE184137,GSE217802_1_v_0_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
synaptic vesicle	GO Cellular Component Annotations 2015	1.0	null
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06286
TBX20-22080862-HEART-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.298
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898706
FOXA1-21572438-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
fastigial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32145
GSE113734_1_v_2_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32999
Perturb_2175_KO_Gsdmd_SRP366634	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
hsa-miR-1184	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4667-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.103199
REST_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKLU1	CCLE Cell Line Gene CNV Profiles	1.0	1.54232
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41825
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDUFB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.76777
vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906517
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112714_2_v_0_ctnnb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918761
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051051
Adamantinous craniopharyngioma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25146
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A465-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_5_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE199543,GSE239447_0_v_4_ezh2_human	RummaGEO Gene Perturbation Signatures	1.0	null
globose nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.98636
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_4day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.65689
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LX-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TNFRSF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00128
ZNF551	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73601
INPP5J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52184
REST_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.070585
anterior (rostral) cingulate (medial prefrontal) cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.35736
GLP1R	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5158-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DDAH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.388
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SPI1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972169
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08053
Adrenocortical carcinoma_ACC_TCGA-OR-A5LO-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CALU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43161
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.47843
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
ZBTB42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23663
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.406
SKMEL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.7345
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.936885
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917921
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
inner CP in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.882528
SHSY5Y	CCLE Cell Line Gene Expression Profiles	1.0	1.53391
oral mucosa	HPA Tissue Protein Expression Profiles	-1.0	-0.770588
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.16435
PA2G4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07652
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.839904
coronary artery disease	GAD Gene-Disease Associations	1.0	null
UBE3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79864
heart	GTEx Tissue Gene Expression Profiles	1.0	0.893755
PTDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07784
external granular (germinal) layer of lower rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.3601
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_42_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971312
Superior temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.731
GSE210101,GSE210114_5_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05287
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LA-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intestine-407 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.516
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989329
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.065721
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-4522	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
hsa-miR-449b	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
JPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21551
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_12854_KD_Pdx1_SRP149543	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
UBL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48348
H3K27me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83226
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10686
C21orf91	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.399
VCX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7785
PAK1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97385
A704	CCLE Cell Line Gene CNV Profiles	1.0	1.58632
GTEX-Q2AG-0011-R7A-SM-2HMJP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841011
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
SDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12569
TEAD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79216
REST_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8905236-mmc2.xlsx-Table_S10-Table_S10_Differentially_regulated_genes_in_SPI1_high_vs_low_group_in_CGGA_GBM_dataset_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I6-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061953
SNAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52218
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59124
LCMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99876
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.76456
GTEX-WWYW-3026-SM-3NB36	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15118
ARIH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17187
PRDM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.70192
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962041
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05277
PAM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23902
TDGF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65078
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.32905
NDUFB10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40595
HCST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16578
FLI1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MVD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40365
GSE144231_3_v_5_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36761
Synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.159
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12207
Major facilitator superfamily domain	InterPro Predicted Protein Domain Annotations	1.0	null
SOX2-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24796
membrane	GO Cellular Component Annotations 2015	1.0	null
hsa-miR-10a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
CYB5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57733
cerebellar cortex_35 pcw_F_12295	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.87272
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.974242
Granular vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.302
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MRPS18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51246
GSE205163,GSE205164_5_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
ATP6V1G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.924
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FARSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34618
KMS27	CCLE Cell Line Gene Expression Profiles	1.0	1.46912
RIPK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.07254
GTEX-QVUS-2926-SM-3GIJB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.937229
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6GW-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
AURKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28113
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COPS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15546
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.848881
LCLC97TM1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.54499
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07143
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.53212
TTLL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05207
ZFP36_Deficiency_GDS2456_707_mouse_Fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.946292
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1915	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
PON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.04144
orbital frontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.978451
Ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCT4-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ENPP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73938
mRNA_GADD45A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19694
GSE210101,GSE210114_4_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZSCAN25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.17473
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-0011-R11A-SM-2TF6F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20709
ZNF93	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7929
amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SMIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67912
SOX2_Deficiency_GDS4853_322_human_AZ-521 gastric cancer (GC) cell line - 24 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Perturb_150_KD_Fto_SRP144034	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.52806
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
COL2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35253
TAF1	ENCODE Transcription Factor Targets	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07491
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GSE173911,GSE173917_0_v_1_morc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Spinal muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.528
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52633
ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
DEGS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16841
REST_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic vesicle part	GO Cellular Component Annotations 2015	1.0	null
GSE183251_7_v_3_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199606_5_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12788
CADOES1	CCLE Cell Line Gene Expression Profiles	1.0	1.44627
synapse part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.779583
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12717
C11orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17346
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC-20876797-MEDULLOBLASTOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AICDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88468
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6790-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03948
orbital frontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.915639
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02506
cortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03944
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Mesothelioma_MESO_TCGA-SC-A6LN-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO704	CCLE Cell Line Gene Expression Profiles	1.0	2.00369
GSE107854_2_v_0_prmt5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
ZNF542P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.73681
FBXO21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62149
DUS1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52379
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
KLHL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87587
IM95	CCLE Cell Line Gene Expression Profiles	1.0	1.40849
GSE210101,GSE210114_5_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.06926
HPAFII	CCLE Cell Line Gene CNV Profiles	1.0	1.78995
VZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.04176
KPNRTBM1	CCLE Cell Line Gene Expression Profiles	1.0	1.37732
HCC1171	CCLE Cell Line Gene Expression Profiles	-1.0	-2.03524
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stomach_3a	HPA Tissue Sample Gene Expression Profiles	1.0	0.829871
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.86285
urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.054691
Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HLA-B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5514
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-484	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46506
GTEX-N7MT-1226-SM-2D7W4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08938
ZNF841	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87216
hsa-miR-3155	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Acute porphyria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.072
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.03134
PLCB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45086
RCOR1	ENCODE Transcription Factor Targets	1.0	null
hep2c	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.028
TP63_01_197	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61204
ADAMTSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67526
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46358
Basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SETDB1	ENCODE Transcription Factor Targets	1.0	null
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
STX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52375
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00913
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
MAMSTR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0334
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042591
MYOG	ENCODE Transcription Factor Targets	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
PMC9950457-mmc3.xlsx-GRHL2_overexpression_DOWN-gene_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
TCF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0497
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.624512
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0541
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10411
TMEM185A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62618
Perturb_125_KD_Cebpb_SRP041765	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.81701
SIAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47984
MKN45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.72012
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877346
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.05498
Perturb_4945_KO_Rybp/Yaf2/Prc1_SRP247114	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.90593
organelle	GO Cellular Component Annotations 2015	1.0	null
CCDC12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99633
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.99195
NCIH2228	CCLE Cell Line Gene Expression Profiles	-1.0	-1.95543
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84726
Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SCA1_Knock-in_GDS1756_234_mouse_Forebrain tissue - 12 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TET1-21490601-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC8384902-mmc5.xlsx-H128_ASCL1_ChIP-Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.48618
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08909
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.15789
ENY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6955
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GEMIN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6909
CC2D1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45739
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.073
GSE143212_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
hsa-miR-516a-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.541706
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-IF-A4AK-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BW-A5NQ-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
QGP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96351
NOC2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07837
primary somatosensory cortex (area S1, areas 3,1,2)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.431
NAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05664
DGUOK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49457
brain	HPA Tissue Gene Expression Profiles	1.0	1.45249
RAB32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.53096
KDM5B-21448134-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
VPS37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50124
EGR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	2.92265
GSE149075_1_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10291
H3K27me3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX2_KO_GDS4445_354_mouse_E11.5 XY embryonic gonads	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE199874_4_v_5_gabpb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205291,GSE205292_1_v_3_drd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11358472-41467_2024_51851_MOESM4_ESM.xlsx-Sheet1-Supplementary_Table_4_gene_expression_levels_for_323_genes_connected_to_EWS-WT1_in_JN-DSRCT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
stratum pyramidale of rostral CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26739
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
SLC29A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52274
VZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.875871
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Presynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.327
CTRL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65857
SP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.859902
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12121
Wound botulism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
hsa-miR-34c-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KMT2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51715
GTEX-X261-0011-R11A-SM-4E3JY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997856
NMB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95767
CTTNBP2NL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0107
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06802
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.2925
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6872
GTEX-TSE9-2926-SM-3DB77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1458
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4876-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FURIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65833
VZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03263
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Unnamed_12_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.829927
SNU46	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57257
NCIH2227	CCLE Cell Line Gene Expression Profiles	1.0	1.97833
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56406
184A1N4	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.11702
cofilin-actin rod	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.554
TCF4_01_185	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59442
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MUS81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14931
GSE198165,GSE198166_7_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08142
hsa-miR-197	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GTEX-X585-0011-R11B-SM-46MUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857568
Synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.335
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.86208
Perturb_78_KD_BAP18_SRP074464	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.76817
GSE162892_4_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WZTO-2826-SM-3NM8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16762
Perturb_13821_KD_Ogt_SRP240961	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.8642
EIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05423
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEx Brain 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-13.5112
ZFAND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.538
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.82835
Cephalothorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.717
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965089
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.93314
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.9769
DEAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09483
TTC21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30677
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.043862
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3268
SP4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4308	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
WAC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10158
MKRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15339
SMURF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79293
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.084
TIA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49694
ZXDC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3455
Kidney Chromophobe_KICH_TCGA-KN-8421-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_13141_KO_Ctr1_SRP165861	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.62386
GTEX-NPJ8-0011-R11A-SM-2YUMS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11581
Lung squamous cell carcinoma_LUSC_TCGA-37-4141-01A-02R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
CD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7951
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.878658
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.9248
COLO668	CCLE Cell Line Gene CNV Profiles	1.0	2.1607
USP33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97911
TXNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36776
SETD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.63873
BPNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41423
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54072
GSE167886_3_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSMC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70029
WWC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85045
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.914193
GSE210101,GSE210114_8_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131887_1_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
AEBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82601
H4K20me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-2826-SM-2I3FU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975172
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2218	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.47006
forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ENSG00000284691	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30719
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.897955
H2BC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56886
SNAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80207
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.3312
Kidney renal clear cell carcinoma_KIRC_TCGA-EU-5907-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04218
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Large_Intestine-intestinal enteroendocrine cell	Tabula Sapiens Gene-Cell Associations	1.0	-0.0684713
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.4189
hsa-miR-1293	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4827
CTCF-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE214248_0_v_1_cxcl8_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR3D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.91454
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.889281
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20435
single-organism transport	GO Biological Process Annotations 2015	1.0	null
Avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.488276
GSE51684,GSE51741_2_v_4_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCSTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08746
GSE201454_1_v_2_ftcd_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TEAD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4324
AACS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44896
IL4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74252
PDE6G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08147
PHYH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72682
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040581
ROCK_INHIBITION_GDS3944_464_mouse_Forebrain astrocytes - 24 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77599
TNIK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15701
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07273
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zfp961	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.5592
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.14465
ABRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22944
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.86973
icSARA deltaORF6_36Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.39623
PMC4051124-1471-2164-15-256-S15.XLSX-WES_IPD-RBCK1_1-Target_RBCK1	Rummagene Transcription Factor Associations 2026	1.0	null
clathrin-coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Pancreas-pancreatic alpha cell	Tabula Sapiens Gene-Cell Associations	1.0	0.849044
GSE178714_5_v_2_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
trans-Golgi network membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.707
RABGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66804
pheochromocytoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.312232
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00759
GSE162892_4_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.919981
abdomen	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.143442
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Milk gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.882
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.79678
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.6227
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00174
EFNB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45684
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.992373
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_2day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.2886
VZ in ventromedial extrastriate cortex (VP)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33741
substrate-specific transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
lateral ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.142546
SIN3A_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2454
PMC5058748-oncotarget-07-31177-s002.xlsx-ZNF224_gene_peaks_promoter-Table_S3_Genes_that_contain_a_ZNF224_enriched_region_within_1_kb_of_the_transcription_ZNF224	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22693
Perturb_13614_KD_Srrm4_SRP041656	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
membrane part	GO Cellular Component Annotations 2015	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_NR2F2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.43989
Perturb_6534_KD_Cd80_SRP338134	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A3KG-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25545
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
globus pallidus, internal segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26451
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.909054
Bacterial nucleoid	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.69
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50325
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.4125
FUZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14123
CAL78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.81677
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF750	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.91298
NHLH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53444
GSE119498_0_v_5_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199034_1_v_0_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
STAT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22646
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19785
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SARM_KO_GDS4842_412_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39021
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_SIN3A_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RMDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80291
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7056-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41647
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.990074
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-2326-SM-32PMR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24827
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Developmental and epileptic encephalopathy 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.048
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.46
AGPAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.371
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MS-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GALNT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.80326
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Unnamed_4_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE250534_4_v_1_cabergoline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ChIP_MYC_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18534
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26396
limitans nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.88407
H3K27me3_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Small_Intestine-intestinal enteroendocrine cell	Tabula Sapiens Gene-Cell Associations	1.0	0.71797
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.57984
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSTF2T	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05404
RBP2_deficiency_GDS2731_62_mouse_embryonic fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLHDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66589
8-MG-BA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE179002_2_v_6_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampal pyramidal layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.395331
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.828043
VEZF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	58.89
ERCC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44698
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tauopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.167224
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.25915
MAP2K3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18392
hsa-miR-4267	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
AK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66725
MYC-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
MTERF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.22479
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852972
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.2163
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892405
Head and Neck squamous cell carcinoma_HNSC_TCGA-DQ-7595-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SLC38A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58192
ELF5	ChEA Transcription Factor Targets	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-GK-A6C7-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79795
KIF18B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11651
LMBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23871
496100496_FWM_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.66784
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02363
Fetal Brain Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.974205
Adrenocortical carcinoma_ACC_TCGA-OR-A5LH-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIN3A_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-4A-A93X-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18535662-TableS2d	GeneSigDB Published Gene Signatures	1.0	null
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2419
frontal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34887
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956677
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.877051
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.59958
ISCU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38008
synapse part	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901391
icSARA deltaORF6_72Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.72597
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4alpha_KO_GDS1915_173_mouse_Small intestine	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ELAC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57512
TCF12	ENCODE Transcription Factor Targets	1.0	null
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.072683
TCF3	ENCODE Transcription Factor Targets	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
UPF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86941
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ERO1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00039
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A66S-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatic Cirrhosis_Liver_GSE6764	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.68737
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
outer SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.989777
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.084
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02508
hsa-miR-516a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
HDAC1	ENCODE Transcription Factor Targets	1.0	null
ING5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80167
trunk	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06412
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
single-organism localization	GO Biological Process Annotations 2015	1.0	null
GSE100464,GSE100465_1_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9630632-Table1.XLSX-diff_exp_genes-Group_2_vs_3_AND_Group_1_vs_3_NOT_Group_1_vs_2_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35152
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE113734_3_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15136
Perturb_16897_KI_Htt_SRP250656	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.73976
POLR3H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5699
globus pallidus, external segment, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32184
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76172
hsa-miR-4307	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
GSE216274,GSE216292_4_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.852502
RCN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00088
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10684
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ETS1	ENCODE Transcription Factor Targets	1.0	null
TFAP4::FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8459
AP3D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65996
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1241
ZHX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04641
SESTD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80054
cerebrospinal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.250627
GABPA	ENCODE Transcription Factor Targets	1.0	null
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-509-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
hsa-miR-3155b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-8255-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.25758
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.973368
establishment of localization	GO Biological Process Annotations 2015	1.0	null
CBX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33491
SLC39A8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18174
alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.168148
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20152
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8037
GSE218060_7_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GLUD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77879
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Catalytic step 2 spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.69
WHSC1	ENCODE Transcription Factor Targets	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Mesothelioma_MESO_TCGA-NQ-A57I-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899055
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0951
synapse part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916771
OSBPL8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47187
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.074269
GTEX-T2IS-2926-SM-32QPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28735
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCDC103	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5438
LCLC103H	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59269
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.13758
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NDUFA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85871
EGR1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51412
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112714_2_v_1_ctnnb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856736
inferolateral temporal cortex (area TEv, area 20)_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0275
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JPH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40401
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03355
BMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60462
RADX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30539
SZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.829807
SOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99377
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.906574
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OR2A4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.19321
CDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06286
CALHM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11888
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.74821
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03454
FOXRED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.79371
clathrin-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.884705
WDR26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30413
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058326
CDK5RAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88943
Foodborne botulism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.527
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE90019,GSE90020_5_v_2_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF486	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.05111
MMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16545
C19orf44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13757
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84519
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.23511
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988975
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Major facilitator superfamily	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0784
H3K4me1_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_17307_KD_Chrm5_SRP222274	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.72852
hsa-miR-4292	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
CLCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72177
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
CXXC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17286
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56068
NCIH2066	CCLE Cell Line Gene Expression Profiles	1.0	1.9134
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02481
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01826
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-2226-SM-2TF5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19522
NAP1L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13119
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE216043_11_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARHGAP11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78962
stratum pyramidale of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.68787
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior temporal gyrus, right, bank of the its	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.867791
Childhood electroclinical syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.0
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RBPJ	ChEA Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.836591
PMC5541666__F1	PFOCR Pathway Figure Associations 2024	1.0	null
IL18BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2053
GSE228992_0_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
cerebralcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
BXPC3	CCLE Cell Line Gene Expression Profiles	-1.0	-2.07685
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.137192
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SMAD4	ChEA Transcription Factor Targets	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.2129
SPRED3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15949
primary somatosensory cortex (area S1, areas 3,1,2)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.1312
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062354
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21214
PMC12240782-Table3.xlsx-Sheet1-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.976003
SHISA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19031
GSE205163,GSE205164_3_v_6_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
E2F2_KD_GDS4094_447_mouse_Mammary tumors (Myc-induced)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
COPI-coated Golgi to ER transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.782
ZNF26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56684
COLO684	CCLE Cell Line Gene Expression Profiles	1.0	3.40792
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32699
Skeletal Muscle Male	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.49503
RTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60959
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RERFGC1B	CCLE Cell Line Gene CNV Profiles	1.0	1.33806
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04751
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52278
RBM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6727
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
no abnormal phenotype detected	MPO Gene-Phenotype Associations	1.0	null
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19294
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210101,GSE210114_2_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE145215_0_v_1_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
XRCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77053
B9D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27574
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31544
GSE210101,GSE210114_1_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM139	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0277
Neurobehavioral Manifestations	CTD Gene-Disease Associations	1.0	1.03235
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GPR75	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65059
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846598
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
Venom gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.954
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A719-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12211354-12915_2025_2224_MOESM6_ESM.xlsx-Sheet1-Sheet1_The_source_list_of_zebrafish_Npas4b_targets_from_human_NPAS4_targets_in_CHEA3_database_NPAS4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	1.0	null
REST_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NIBAN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03398
RAB41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15397
SSBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99245
JAZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90463
GSE190316,GSE190324_10_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.477
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3120-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
GSE214382,GSE214383_5_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62728
LPXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17158
KIF21B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45203
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.978451
WARS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.09196
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_Panc1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hippocampus (hippocampal formation)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.879
Lung adenocarcinoma_LUAD_TCGA-86-8358-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Eye-eye photoreceptor cell	Tabula Sapiens Gene-Cell Associations	1.0	10.6796
GBF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55051
LN-229	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-133a	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
SAP30BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33334
hsa-miR-589	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
AHRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08672
MONOMAC1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.50755
NCIH1385	CCLE Cell Line Gene Expression Profiles	1.0	2.1377
ZNF143	ENCODE Transcription Factor Targets	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
KRIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06462
Rectum adenocarcinoma_READ_TCGA-AG-3731-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
18787207-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GSE68156_3_v_4_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_3_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
REST	ChEA Transcription Factor Targets	1.0	null
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971854
normal phenotype	MPO Gene-Phenotype Associations	1.0	null
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26045
FBXO41	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06516
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
CDKN1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49067
primary motor cortex (area M1, area 4)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.898448
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053794
17616640-TableS3	GeneSigDB Published Gene Signatures	1.0	null
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941382
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-2W-A8YY-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.841577
SUPT11	CCLE Cell Line Gene CNV Profiles	-1.0	-2.02355
ELF1	ENCODE Transcription Factor Targets	1.0	null
TMEM158	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34723
NCIH2106	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50884
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.319
MHHNB11	CCLE Cell Line Gene Expression Profiles	1.0	1.78665
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
GPR161	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77095
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210101,GSE210114_7_v_3_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
TET1-21451524-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
SW403	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38887
mRNA_KLF4_18264089	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7881-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925305
STK40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9586
Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190316,GSE190324_1_v_9_rbm4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CLCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17448
GTEX-N7MS-2526-SM-2D7W3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35052
Parahippocampal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	1.89599
MOB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56753
AKNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14372
GSE100102_2_v_5_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.026
C8orf82	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35718
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10324
CLBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87709
PAFAH1B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36333
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039333
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06109
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ATP13A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06659
STAT1-17558387-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LRRC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.67598
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Tail	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.932
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79085
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34717
CMLT1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.55107
GSE67266_7_v_4_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SHISA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4056
SDHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58902
MED31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38419
c2c12	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.34203
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939954
H3K4me3_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ETV2-25802403-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PNKP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59046
VZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.927207
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS	Rummagene Transcription Factor Associations 2026	1.0	null
REST_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053428
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25476
PGR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9453
VSX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35465
CEP72	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05569
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09159
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.844787
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.981357
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2	ChEA Transcription Factor Targets	1.0	null
S100PBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06672
GSTO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86354
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66225
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RNF125	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14727
ZNF766	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4764
GPRIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66553
FAM222B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43542
PINX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.30723
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05617
TTC9C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25972
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.47591
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74991
Neurula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.922
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4708
BSDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99994
SRF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06693
ZNF654	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64367
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.904978
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31713
HFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00487
cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
peritoneal fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.726097
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
NDFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07413
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.24988
TPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26852
Sarcoma_SARC_TCGA-DX-A3UC-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
uterus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.17908
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15193
SFN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4167
PIP5KL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00767
anterior group of nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.852165
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.82162
cellular process	GO Biological Process Annotations 2015	1.0	null
GSE216043_10_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC2_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE143212_0_v_3_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NFE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27157
hsa-miR-2861	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
TEAD2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7509
PLEKHA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28474
DHFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99564
ECC10	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97401
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12961
LIPT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65556
dorsolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21257
SIN3A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.946
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.9742
STYXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93348
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMEM65	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86836
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99301
GSE111660_1_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GABPA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ITCH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31202
ZNF317	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7548
adrenal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.243605
H2BC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29002
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.950179
ZNF384	ENCODE Transcription Factor Targets	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.60902
GET4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27982
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
adiposetissue	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.74661
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EL-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1385	CCLE Cell Line Gene CNV Profiles	1.0	1.52694
A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^4_None_GSE44441	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.12299
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.002
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ACOT8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.07038
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210101,GSE210114_6_v_10_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_RHOX6_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05536
COPS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00017
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CCDC174	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.35117
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.080037
ATP5F1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46715
no abnormal phenotype detected	MGI Mouse Phenotype Associations 2023	1.0	null
SLC4A11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03133
CD99	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25459
Exocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.156
Amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SORBS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.87988
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13162
15273739-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
STIMATE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97515
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06098
hsa-miR-1262	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.8797
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CREM	ChEA Transcription Factor Targets	1.0	null
BLTP3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45881
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMYM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33856
MTHFSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93327
GSE174418,GSE174421_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOWAHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.42698
NEK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20933
GRPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51217
ABHD13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44663
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21539
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.381
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SLC46A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58285
MPND	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.1597
TLE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06062
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57875_1_v_0_hnrnpl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9996951-40659_2023_417_MOESM3_ESM.xlsx-Osteo_vs_MSC_Array2_hypo_er_txt-Upstream_NAME_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.9172
GSE232218_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40991
ATG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05753
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CNR_KO_GDS2820_636_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inner portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.856864
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.070877
GSE150669_2_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE227891_5_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
TFDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77876
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54119
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966565
dorsolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.48317
GSE148252_1_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AU565	CCLE Cell Line Gene CNV Profiles	-1.0	-2.36159
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05978
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71811
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.56501
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2619
Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898075
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938637
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.30419
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
Paracentral lobule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.656
ZNF320	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88534
VZ in caudal cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.853151
MYC-20876797-MEDULLOBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
EMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.6493
hsa-miR-3925-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151782_6_v_7_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11163
MOB3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22942
LHFPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14481
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Synaptic vesicle, readily releasable pool	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.982
PANC0327	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60435
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EIF4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47229
NCIH524	CCLE Cell Line Gene Expression Profiles	1.0	1.64095
hsa-miR-4423-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A411-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6017-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTDSP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39836
synaptic vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
FKBP1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65219
Prostate adenocarcinoma_PRAD_TCGA-HC-A632-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056894
USF1	ENCODE Transcription Factor Targets	1.0	null
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	3.18888
HPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13422
H4K20me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NHERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05227
hippocampus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.165402
GSE70499_3_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.80624
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67338
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FOSB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.99949
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052566
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.084
REST_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79989
lung	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25541
OTUD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03386
ITGA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97667
synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.974198
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07107
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
AADAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33298
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PDIA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81003
GTEX-Q2AG-2826-SM-2HMJQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25341
DNAJC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58217
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.178299
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A7M9-01A-23R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
short insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.969476
EP300_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Colon muscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.541
MTAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39876
Coronary Artery Disease	dbGAP Gene-Trait Associations	1.0	0.148655
ARL4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56362
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_0_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
VZ in rostral cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.977658
outer SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26915
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19065
basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.589295
IP6K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76955
temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824383
ZNF660	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34856
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18915
PPIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25457
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-0.770588
H3K27me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AR	ChEA Transcription Factor Targets	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22265
EXOSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86096
DNAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94586
Specific language impairment	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.348
FHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55628
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30664
GTEX-T6MN-2526-SM-32PMN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18231
peritoneum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.196723
TPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21026
DNAJC18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12683
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
TET1-21490601-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
STMN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.90191
abducens nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16765
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.09454
SARS-BatSRBD_Day4_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.90282
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
TRIR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2199
NEUROD2-26341353-CORTEX-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.871288
Hepatoerythropoietic porphyria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.102
AP2M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0248
Inflammation	CTD Gene-Disease Associations	1.0	1.19835
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CST3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38581
HOXB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94011
hsa-miR-329	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBE2T	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20142
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.44976
RELB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4769
GSE236280_0_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
subarachnoid space	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241746
TCF12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3176	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
GSE205163,GSE205164_1_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060965
ACOT7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46338
GSE205687_1_v_0_mta1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TSC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02604
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03426
inner CP in dysgranular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.842953
SIN3A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PARP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63912
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.91667
GSE148252_1_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	31.2798
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904949
Choanomastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.905
PMC5541666__F1	PFOCR Pathway Figure Associations 2023	1.0	null
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07079
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ion transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
OTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14817
DVL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52389
PHTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02544
Kidney renal papillary cell carcinoma_KIRP_TCGA-KV-A74V-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76958
cytoplasmic membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
SOX4	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TMEM199	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68251
UCHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5147
Perturb_1261_KO_Ahnak_SRP307472	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.06981
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01084
PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Supplemental_Table_6_Genes_downregulated_in_NEUROG3-_-_hESC_line_differentiated_to_pancreatic_endocrine_progenitors_d13_NEUROG3	Rummagene Transcription Factor Associations 2026	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
striatum_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17745
GON7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.74069
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA4_INACTIVATION_GDS3663_519_mouse_Endothelial-derived cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
TMX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70805
CDC16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.66043
AIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97073
PMC7893891-12860_2021_343_MOESM1_ESM.xlsx-Fig3C_D13vsD7-FOXP2_FOXP2	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LAPTM4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.57302
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SINHCAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77418
Synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.289
HMGB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59602
PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasmic part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE74528_0_v_1_trex2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55637
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16874
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
ZNF45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39758
TP53	ChEA Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2889-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE179002_0_v_8_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29764
MDAMB134VI	CCLE Cell Line Gene CNV Profiles	1.0	1.7275
GTEX-NPJ8-2626-SM-2D7W2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08374
PMC7895828-41419_2021_3488_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_3_List_of_deregulated_genes_in_c-MYC_altered_human_HCC_from_TCGA_LIHC_dataset_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
SCC4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36188
APH1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79192
hsa-miR-570	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
496100608_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.20409
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.070173
GSE190186,GSE190188_8_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180185_9_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
IMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2614
ATF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
KP2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33268
Acute Myeloid Leukemia_LAML_TCGA-AB-2935-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MTX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.002
SOX11-23321250-Z138-A519-JVM2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
PKD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08764
REST_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02998
PMC12885947-44386_2025_32_MOESM1_ESM.pdf-23-ZNF469_ZNF469	Rummagene Transcription Factor Associations 2026	1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRDM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2738
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.19
HDHD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1754
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.08498
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1933
A4FUK	CCLE Cell Line Gene Expression Profiles	1.0	1.73887
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053411
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.80114
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Mesothelioma_MESO_TCGA-SC-A6LM-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4724-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Perturb_16431_KD_E2f4_SRP327850	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.78903
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216273,GSE216292_14_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TIMM17A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0672
synapse	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.5529
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
SUPT7L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65541
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PELI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72011
spinal cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055198
ZNF777	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3612
YH13	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69589
MRPL28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6369
16293602-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928282
RC3H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55322
GSE179002_0_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormal gait	MGI Mouse Phenotype Associations 2023	1.0	null
NAA38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80978
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ethanol_rattus norvegicus_gpl341_gse1996	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.167125
pineal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.597666
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35087
PMC10111863-supp_gad.350269.122_Supplemental_Paun350269_FileS3.xlsx-A_ASCL1-regulated_DGE-geneID_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC25A32	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72709
JHOS2	CCLE Cell Line Gene CNV Profiles	1.0	2.53876
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.27665
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.056105
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GRHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2209
ARF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82131
pyramidal layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.935825
RIT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64541
HARBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55987
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1136
IGR39	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44002
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_5374_KO_Setdb1_SRP226379	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.49691
MPZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65865
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.904134
hsa-miR-34a	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.89175
ASIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53355
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01051
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916563
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MV-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MP-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.71339
RCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78645
icSARS CoV_72Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.32134
transporter activity	GO Molecular Function Annotations 2015	1.0	null
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06746
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-639	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CBP-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ7-0011-R11A-SM-2I3E8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04553
GSE211224_2_v_0_donepezil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12826982-mmc5.xlsx-Table_S4-Supplementary_Table_S4_Differentially_Bound_Down-regulated_Peak-Related_Genes_in_Flag-SOX3-HSV-1_vs_Flag-SOX3-Mock_SOX3	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH292	CCLE Cell Line Gene Expression Profiles	-1.0	-1.57836
DMS454	CCLE Cell Line Gene Expression Profiles	1.0	1.53781
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE150669_0_v_3_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FEZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.14924
H3K27me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIRT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1998
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-0.770588
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GPI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02449
PUSL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40921
NCIH810	CCLE Cell Line Gene Expression Profiles	1.0	1.43856
BPHL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3123
HDQP1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.44082
CNN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95195
17616640-TableS1	GeneSigDB Published Gene Signatures	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF76	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99499
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21748
BARHL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1576
cytoplasmic membrane-bounded vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
DNASE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19401
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.49898
CA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18742
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GJC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3878
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MYRFL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.0212
MOV10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.80999
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40916
Pancreas-pancreatic delta cell	Tabula Sapiens Gene-Cell Associations	1.0	0.0626023
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07348
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
THTPA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6788
icSARA deltaORF6_24Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.30535
Presynapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.095
GTEX-X4XX-2926-SM-3NMB1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938336
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3593
TM9SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57073
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75232
Sarcoma_SARC_TCGA-HB-A5W3-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYOD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8695
avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
CBX3_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67467
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869492
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0355
TTF2	ChEA Transcription Factor Targets	1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178907_5_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55E-0011-R9A-SM-2TC6C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.854082
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46579
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936819
GSE201217_2_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IGR37	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63807
U2OS	CCLE Cell Line Gene CNV Profiles	-1.0	-1.391
LDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48323
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31531
Uterine Carcinosarcoma_UCS_TCGA-N8-A4PI-01A-21R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0077
globus pallidus, external segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11549
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
PHLPP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.1641
vagina	HPA Tissue Protein Expression Profiles	-1.0	-0.770588
HENMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39744
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH2141	CCLE Cell Line Gene Expression Profiles	1.0	1.35937
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
chr12_108916549_C_T_b38	GTEx eQTL 2025	1.0	3.78545
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRR36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77149
Perturb_14132_OE_Lmnb1_SRP299168	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.77185
AGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20013
REST_Panc1_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7374-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ATP5MC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34677
UBF1/2-26484160-CHIP-SEQ-FIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
LMO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7774
SOX17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63008
NPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51951
SPTLC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30836
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5B-21448134-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PSPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17234
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.004
HACD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83425
KM12	CCLE Cell Line Gene CNV Profiles	1.0	1.51388
POLH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2335
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.849078
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pyramidal neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.395709
ARFGEF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18218
cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
YIF1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98854
Peritoneal dialysis fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.252
CENPQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53289
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999946
TRMT44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73387
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHCHD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37181
UBQLN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58288
EGR1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPRD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93819
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Alzheimer's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.304
stratum pyramidale of rostral CA3	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.979793
KDM2B-26808549-CHIP-SEQ-REH-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PEX16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55428
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
AMIGO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45537
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.55251
GSE183335,GSE183351_1_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.53433
GSE142232,GSE142234_0_v_3_gcgr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_3_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
membrane-bounded vesicle	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.997265
RAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.43237
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOCS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8597
ACSM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71391
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GPBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7969
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927866
MEF2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71949
Central nervous system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.009
PMC6335596-mmc2.xlsx-RNA-seq_Day_12_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_12_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23468
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06303
hsa-miR-498	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC3_KO_GDS4886_29_mouse_heart - 6 week old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08289
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
SLC35E3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3758
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE180185_4_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FSCN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19424
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25451
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_197_KD_Map2k5_SRP110236	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.68604
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.885568
ion transport	GO Biological Process Annotations 2015	1.0	null
polymorphic layer of rostral subiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.963745
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850682
Temporal lobe epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.352
OFD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30376
CNIH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79693
GSE158320,GSE183351_2_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_5_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15135
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.066858
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.084
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE100102_2_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984732
RPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90445
hsa-miR-1237	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Perturb_13056_Mut|OE_Sik3E13_SRP334442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.3647
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0201
increased mean corpuscular hemoglobin concentration	IMPC Knockout Mouse Phenotypes	1.0	null
NCI-H810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2129
TRAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.41097
TDP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66024
MMRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40881
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8851354-Table_6.xlsx-STAT3-bound_genes_GM12878-Supplementary_Table_6_STAT3-bound_unique_genes_in_GM12878_cells_STAT3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210101,GSE210114_2_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KIFC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50637
hsa-miR-219-1-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
basal ganglia disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.270108
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.10353
TBC1D16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32665
REST_01_145	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.92015
HYOU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76707
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HD-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4904-01A-02R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H4C11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29859
cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.059172
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01078
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.2175
VASH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57152
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199606_5_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE141143_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32665
ACHN	CCLE Cell Line Gene CNV Profiles	1.0	1.85011
HEATR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21724
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32201
FUS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56861
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.951338
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890888
Chromaffin cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.976
NECTIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06264
TULP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00503
SAP30	ENCODE Transcription Factor Targets	1.0	null
ESPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49004
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CXXC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21315
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FBLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21975
STAT3	ChEA Transcription Factor Targets	1.0	null
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860384
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10192
JURKAT	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61675
SOX11-23321250-Z138-A519-JVM2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.30243
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PNPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68953
ZNF468	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24236
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RHOXF2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10149
ZIC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.01984
GSE149075_1_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AP5M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73914
synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.606973
kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.063401
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082686
EGR1	ENCODE Transcription Factor Targets	1.0	null
Focal epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.291
GSE167886_2_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CBX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87273
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S6-01A-21R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4001
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5B-Up_H3K4me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
PXMP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.14397
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
temporal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.110134
corpus callosum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.4817
ATP6V1F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56232
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44733
DHX15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.3872
DPEP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.63158
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BORCS6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49422
H3K27me3_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.999441
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16114
hsa-miR-4739	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
stratum pyramidale of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.93114
SMIM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78483
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.7
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07754
T3M4	CCLE Cell Line Gene CNV Profiles	1.0	1.53928
organelle part	GO Cellular Component Annotations 2015	1.0	null
MRPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86232
inner CP in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01915
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903368
MATK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77796
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.52518
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.896925
PXDNL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93826
GSE225901_2_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell junction	GO Cellular Component Annotations 2015	1.0	null
SEPTIN11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31886
NOTCH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.191
BICDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71548
GSE122101,GSE122103_0_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EBNA2-21746931-IB4-LCL-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
HDAC2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HARA	CCLE Cell Line Gene CNV Profiles	1.0	1.33806
FGFR3_knockdown_34_GDS4454	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.03574
SBC5	CCLE Cell Line Gene Expression Profiles	-1.0	-1.59786
transmembrane transporter activity	GO Molecular Function Annotations 2015	1.0	null
fusiform gyrus, right, bank of cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.832356
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.37758
EFEMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50445
Intestinal botulism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.533
KDM4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04613
layer VI of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.932444
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87809
RPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.01296
PPP4R3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.69155
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.827174
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IRX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90618
REST_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.890539
Perturb_5019_KD_Dppa4_SRP187465	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.61366
CECR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9119
ZNF429	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.04931
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PFKFB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.43935
TNPO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56582
callosal sling	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.841692
LMO2-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05556
GSE131887_1_v_3_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46586
Prostate adenocarcinoma_PRAD_TCGA-J9-A52B-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88402
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.58678
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEx Brain 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-13.5422
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MONOMAC6	CCLE Cell Line Gene CNV Profiles	-1.0	-2.1108
vesicle	GO Cellular Component Annotations 2015	1.0	null
C2orf15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92296
nih 3T3	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.24163
GSE179002_2_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042396
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	1.64811
SNURF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89246
HUPT4	CCLE Cell Line Gene CNV Profiles	1.0	1.89553
GSE189683_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dementia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.165655
PIGU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48871
synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.136023
GTEX-WHSE-2926-SM-3NMBG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05737
MYC	ChEA Transcription Factor Targets	1.0	null
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Transport vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.874
E2F4	ENCODE Transcription Factor Targets	1.0	null
TAF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36951
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08967
increased mean corpuscular hemoglobin	IMPC Knockout Mouse Phenotypes	1.0	null
GSE225901_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-11A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
ZFYVE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99046
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03926
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06685
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12317
GSE164505,GSE164506_3_v_2_indisulam_human	RummaGEO Drug Perturbation Signatures	-1.0	null
spinal column	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.151914
Perturb_15337_KO_Nfkbiz_SRP255398	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.40379
CNNM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33087
CEP250	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54115
PDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36015
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.7383
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ILK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7787
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
RAB13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.92351
SARS-CoV MA15_Day2-PFU-10^5_None_GSE50000	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.90952
hsa-miR-1273f	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
PMC5352183-oncotarget-08-624-s009.xlsx-Table_S20-1_indicates_that_the_gene_is_both_a_TP53-MW_and_a_TP53-MSN_gene_in_the_correponding_cancer_and_0_indicates_not_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
H4K20me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SWSAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87919
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PI4K2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70991
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-2526-SM-2TC6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14957
primary somatosensory cortex (area S1, areas 3,1,2)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.928563
SOX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33137
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_Panc1_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.41934
ECC12	CCLE Cell Line Gene Expression Profiles	1.0	2.51209
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
PMC8684775-CTM2-11-e640-s002.xlsx-Sheet1-Table_S3_MAF_file_of_the_CCS_samples_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4691-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.181316
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.61165
malignant glioma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.216332
single-organism process	GO Biological Process Annotations 2015	1.0	null
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46813
AMFR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.93165
Lung adenocarcinoma_LUAD_TCGA-35-5375-01A-01R-1628-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09936
STRADA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02117
THEM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72522
D2HGDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40748
OGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61438
HUP-T3	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB436	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50635
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963253
REST_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15264
UPF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.12466
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDC42SE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23815
Neurosecretory vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.429
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inferior frontal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.575
A-Vietnam-1203_CIP048_RG4-2004(H5N1)PB2-627E_7day-MOI-10^4_None_GSE43301	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.72788
GSE205163,GSE205164_1_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92084
HMGN3	ENCODE Transcription Factor Targets	1.0	null
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8419
TAF7	ENCODE Transcription Factor Targets	1.0	null
NANOG	ENCODE Transcription Factor Targets	1.0	null
GTEX-QDT8-3026-SM-32PKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07192
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5258
Huntington's Disease_Lymphocyte_GSE8762	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.90484
ENG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03256
Porphyria	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.02
MFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96321
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7018-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNASEH2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37473
choroid plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.192449
U2SURP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.97599
RBIS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58344
GSE217363_4_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ADPRS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20588
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SLX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96502
KDM5B	ChEA Transcription Factor Targets	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19499
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB134VI	CCLE Cell Line Gene Expression Profiles	1.0	1.67349
KNS42	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43142
GSE221327_8_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C2CD4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27302
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210101,GSE210114_8_v_9_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27671
PCDHB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19513
PDX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4981
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039878
GSE173873_8_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9124206-41419_2022_4940_MOESM8_ESM.xlsx-DEG_PACA-US-ID_PTF1A	Rummagene Transcription Factor Associations 2026	1.0	null
PTPRCAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33445
Electric organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.079
ADGRB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47199
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3203
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.829927
Perturb_4991_KO_Mettl5_SRP268611	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.40668
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.044855
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EML4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3767
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.10737
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24438
WIPI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67623
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-QMR6-1326-SM-32PLB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959472
Lung adenocarcinoma_LUAD_TCGA-55-8507-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3JH-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_854_KD_Ogt_SRP297858	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.50247
SBNO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37814
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
CX3CL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89057
FLI1	ChEA Transcription Factor Targets	1.0	null
GSE112714_2_v_3_ctnnb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FGFR3_knockdown_173_GSE41035	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.0357
hsa-miR-4756-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
MYC-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SPIN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18738
HADHB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2757
MAPRE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46468
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE239844_8_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTBP2	ENCODE Transcription Factor Targets	1.0	null
NICN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44003
NUDT21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39331
PRMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52155
ABCB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60441
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946114
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8258
EDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39992
GSE210101,GSE210114_6_v_3_urod_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE193541_0_v_3_nifurtimox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NUDCD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28976
cytoplasmic vesicle	GO Cellular Component Annotations 2015	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	1.52389
ORC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29707
CYB5R2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42631
RBBP5	ENCODE Transcription Factor Targets	1.0	null
REST_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.22769
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE151119_2_v_0_hsf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6855629-pone.0225186.s008.xlsx-Sheet1-DEGs_downregulated_in_SK-N-SH_MEIS1_OE_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.147991
hsa-miR-3922-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35975
NKX2-3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80208
PKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04834
ZDHHC21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1614
KM12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EIF5A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90811
primary auditory cortex (core)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.996521
REST_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A1CF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92122
REST_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06086
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S3-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE133087_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MMS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05468
COX4I1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99012
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.928707
impaired righting response	MGI Mouse Phenotype Associations 2023	1.0	null
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33091
BCL6B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6708
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45678
cyclophosphamide_rattus norvegicus_gpl1355_gse48407	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNRF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.82246
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_8_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
SCRT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.248
hsa-miR-541	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
PMC6299095-41389_2018_108_MOESM4_ESM.xlsx-T47D-TRPS1_peak-gene_symbol_TRPS1	Rummagene Transcription Factor Associations 2026	1.0	null
PU.1_KD_GDS2411_175_mouse_Preleukemic hematopoietic stem cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
SHISA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.16347
CNN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79812
SARNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59848
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.911401
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	1.88911
Exocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.32
hsa-miR-377	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32527
C1QTNF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35596
ELF5-23300383-T47D-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CFAP119	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55415
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.87069
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.294581
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7569
ARVCF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.97977
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4710-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27842
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM120B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28839
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37904
TSG101	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08244
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.360782
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.9906
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.770588
ATG4C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28079
XRCC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98288
VIRMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2249
CRBN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40974
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36658
ARID1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92579
GSE160246_0_v_7_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.944045
Perturb_4554_KD_Mcrs1_SRP126769	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.76402
Exocytic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
HSF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.38398
PPM1M	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53034
synaptic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCDC43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04891
GSE167218_1_v_0_hoxd12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_7_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
IGF2R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.67392
RCOR1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLP8	CCLE Cell Line Gene Expression Profiles	1.0	1.60505
CCDC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28801
stratum pyramidale of caudal CA2	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.916
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07826
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.36176
hsa-miR-133b	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
ANXA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7626
SKNFI	CCLE Cell Line Gene CNV Profiles	1.0	1.46931
Sarcoma_SARC_TCGA-DX-A7EL-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949934
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
SEZ6L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33399
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188