association dataset threshold value standardized value r6 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56797 Adrenocortical carcinoma_ACC_TCGA-OR-A5LP-01A-11R-A29S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null upper limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.65075 H3K27me3_bronchial epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE156907,GSE160237_1_v_0_pten_mouse RummaGEO Gene Perturbation Signatures 1.0 null JHESOAD1 CCLE Cell Line Gene Expression Profiles -1.0 -1.61849 PMC4149371-pone.0105180.s010.xls-SOX2-GENE_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null PMC10915192-ab-23-0304-Supplementary-Table-S7.pdf-17-MEIS2_MEIS2 Rummagene Transcription Factor Associations 2026 1.0 null GSE174418,GSE174421_2_v_3_mettl5_mouse RummaGEO Gene Perturbation Signatures -1.0 null PKBalpha_KO_GDS1784_193_mouse_Embryonic fibroblasts (MEFs) - 0 hour GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051766 Acute Myeloid Leukemia_LAML_TCGA-AB-2977-03B-01T-0760-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Synaptic vesicle, readily releasable pool COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.886 HCC366 CCLE Cell Line Gene Expression Profiles -1.0 -1.98764 gilles de la tourette syndrome GWASdb SNP-Disease Associations 1.0 0.688771 PDSS2_KO_GDS3454_120_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null DDX56 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.38397 GSE149264,GSE149267_9_v_1_trp53_mouse RummaGEO Gene Perturbation Signatures 1.0 null Teratocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.733 Prostate adenocarcinoma_PRAD_TCGA-G9-6356-01A-11R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-641 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 GTEX-NL4W-0011-R5a-SM-2I3GD GTEx Tissue Sample Gene Expression Profiles 1.0 1.17404 primary auditory cortex (core)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.05993 MITF-21258399-MELANOMA-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null cytoplasmic vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.766804 PPARD_KO_GDS4320_619_mouse_Pancreas GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null ONDA7 DepMap CRISPR Gene Dependency 1.0 2.14466 H3K9ac_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null 15374961-TableS2 GeneSigDB Published Gene Signatures 1.0 null GTEX-T5JC-0011-R4A-SM-32PLT GTEx Tissue Sample Gene Expression Profiles 1.0 0.875935 GTEX-N7MT-0011-R5a-SM-2I3G6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.34457 PPP4R1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07113 stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.70845 GSE216273,GSE216292_0_v_3_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null GSE149870_0_v_1_pfn1_mouse RummaGEO Gene Perturbation Signatures 1.0 null mediodorsal nucleus of thalamus_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -3.52575 hsa-miR-509-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 GSE223008_7_v_12_calhm6_mouse RummaGEO Gene Perturbation Signatures 1.0 null granular layer of rostral dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.943378 forebrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.771514 pterigoid muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.2587 hsa-miR-3682-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 EZH2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null forebrain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PMC6938365-pone.0226733.s020.txt--POU5F1_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null GSE88819_7_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null embryonic brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.420766 HOXB3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.6629 Perturb_3444_KO_Acsl6_SRP321472 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.23152 Intrinsic component of postsynaptic density membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.725 POLR2A_cerebellum_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null neuron part GO Cellular Component Annotations 2015 1.0 null organelle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 epidermal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05574 Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mouse - Motor Cortex - Cluster - Vip+ Mybpc1+ GABAergic neuron_3 HuBMAP Azimuth Cell Type Annotations 1.0 null TEF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.7618 Central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.792 olfactory receptor neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.420004 NCI-H441 COSMIC Cell Line Gene Mutation Profiles 1.0 null medial habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08088 Brain Lower Grade Glioma_LGG_TCGA-TM-A7C4-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null emboliform nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.856735 LS411N CCLE Cell Line Gene Expression Profiles 1.0 1.43168 abnormality of the face GWASdb SNP-Phenotype Associations 1.0 0.086905 GSE242199_2_v_5_ntrk2_human RummaGEO Gene Perturbation Signatures 1.0 null hsa-miR-4727-5p TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 core of nucleus accumbens Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.37339 Exocytic vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.285 HCC1833 CCLE Cell Line Gene Expression Profiles -1.0 -2.23547 Intercalated nucleus of amygdala Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.882332 Neurotoxicity Syndromes CTD Gene-Disease Associations 1.0 1.01212 GSE111660_1_v_3_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null USF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.0703 intermediate part of r5B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02548 Nucleus accumbens Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0032 Human - Motor Cortex - Subclass - Vip+ GABAergic neuron HuBMAP Azimuth Cell Type Annotations 1.0 null superficial stratum of PCPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03592 FBXO2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02527 BT549 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.834086 hsa-miR-499a-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Liver GTEx Tissue Gene Expression Profiles 2023 1.0 2.24878 GTEX-S7SE-0011-R11A-SM-2XCDD GTEx Tissue Sample Gene Expression Profiles 1.0 1.17012 GTEX-NPJ8-0011-R11A-SM-2YUMS GTEx Tissue Sample Gene Expression Profiles 1.0 1.06118 Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A819-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG Rummagene Transcription Factor Associations 2026 1.0 null Nmyc_OE_GDS2406_14_mouse_LUNG GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7603-01A-21R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null heart muscle HPA Tissue Gene Expression Profiles 1.0 1.23496 pontine raphe nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.885396 Agranular insular area, ventral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23406 striatum_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.911322 BB30HNC DepMap CRISPR Gene Dependency 1.0 2.69726 G292CLONEA141B1 CCLE Cell Line Gene CNV Profiles 1.0 1.61342 SIN3A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null r4 part of posteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.105 mRNA_TCF3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null GTEX-X4XX-3026-SM-3NMB2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.837566 PRDM1 JASPAR Predicted Transcription Factor Targets 1.0 null trochlear nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.858798 Ebstein anomaly DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.155 medial subdivision of area 10 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.843102 central nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.75191 Glomerular layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.469 CTCF_WERI-Rb-1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Lean body mass GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.504576 Trigeminal nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.599 periventricular stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0056 hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.888754 hsa-miR-136 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 MRTO4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.57102 central glial substance Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.30684 axon part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.212974 COLO 829 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26689 PMC12478272-mmc1.xlsx-Table_S7-Supplementary_Table_7_Proteome-wide_MR_and_sensitivity_analysis_results_using_the_brain_pQTL_dataset_from_Wingo_et_al_1_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null cerebellar cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.17569 Dentate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08937 CEBPB-26923725-CHIP-SEQ-MESODERM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null hilus of the DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39597 SNRPG CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.74394 arterial stenosis GWASdb SNP-Phenotype Associations 1.0 0.206171 GSE111660_2_v_6_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null Amacrine cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.276 CSNK2B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27477 RPL8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.08008 para-high vocal center TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.096 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null obstructive lung disease GWASdb SNP-Disease Associations 1.0 0.407594 asthma GWASdb SNP-Disease Associations 1.0 0.937304 VZ in dorsomedial extrastriate cortex (V2) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.907527 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.592043 Perturb_4482_KO_Silc1_SRP134051 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -2.78589 TC71 CCLE Cell Line Gene Expression Profiles 1.0 2.25277 chr3_63109469_C_T_b38 GTEx eQTL 2025 1.0 1.30714 DFCI024 CCLE Cell Line Gene Expression Profiles -1.0 -3.10801 eye TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.452198 H3K27me3_cardiac mesoderm_hg19_8 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of r6BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56376 ZBTB26 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.8709 gigantocellular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.912996 NCIH2122 Achilles Cell Line Gene Essentiality Profiles 1.0 1.09324 GSE119498_6_v_4_setd5_mouse RummaGEO Gene Perturbation Signatures -1.0 null CAPAN-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26096 ZNF680 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.9114 mantle zone of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.88952 G-361 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14724 Presynapse COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 central part of CEl Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.884344 NCIH2172 CCLE Cell Line Gene CNV Profiles -1.0 -1.63683 H3K27me3_fibroblast of lung_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null r1 part of vestibular nucleus Y Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43921 NCIH1436 CCLE Cell Line Gene CNV Profiles -1.0 -2.20312 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.18098 GSE69244_1_v_0_j147_mouse RummaGEO Drug Perturbation Signatures 1.0 null Dendritic tree COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.997 FOXA1-25552417-VCAP-HUMAN ChEA Transcription Factor Targets 2022 1.0 null EMC10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32951 Perturb_17229_KO_Tsc1_SRP096336 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.17026 496100496_FWM_possible Alzheimer's disease_no TBI_88_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.82563 GTEX-X4XX-0011-R5A-SM-46MWN GTEx Tissue Sample Gene Expression Profiles 1.0 0.924956 PPARD-21283829-MYOFIBROBLAST-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 MEF2D JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.5874 CH25H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1477 Olfactory areas Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.36416 GSE211126_1_v_0_hapln1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SKES1 CCLE Cell Line Gene Expression Profiles 1.0 1.64153 HCC1806 CCLE Cell Line Gene CNV Profiles -1.0 -1.57844 Asthma_Epithelial Cell_GSE4302 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.72517 characterization GeneRIF Biological Term Annotations 1.0 null intrinsic component of organelle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K27me3_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null POU2F1::SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.5868 PMC10099894-NAN-49-0-s001.xlsx-GENIC_INTERSECT_VCF-MID_TBX1 Rummagene Transcription Factor Associations 2026 1.0 null SKBR3 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.611152 A673 CCLE Cell Line Gene Expression Profiles 1.0 2.13763 Anterior olfactory nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.917 GTEX-P44H-0011-R11A-SM-2XCER GTEx Tissue Sample Gene Expression Profiles 1.0 1.28073 POU5F1 ChEA Transcription Factor Targets 1.0 null Stratum granulosum cerebelli TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.629 arteriosclerosis GWASdb SNP-Phenotype Associations 1.0 0.229954 GTEX-TSE9-0011-R4A-SM-3DB7H GTEx Tissue Sample Gene Expression Profiles 1.0 0.826432 Dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.996 BICDL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07675 Pancreatic adenocarcinoma_PAAD_TCGA-US-A776-01A-13R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE160017,GSE160022_1_v_0_trem2_mouse RummaGEO Gene Perturbation Signatures 1.0 null ventrolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.21243 leukemia GWASdb SNP-Phenotype Associations 1.0 0.222108 medial habenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63337 HCC1395 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.835818 GSE223008_7_v_8_calhm6_mouse RummaGEO Gene Perturbation Signatures 1.0 null Diencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.764 r6 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.67145 H3K4me1_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.32497 acute lymphatic leukemia GWASdb SNP-Phenotype Associations 1.0 0.440463 dorsolateral prefrontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.89422 striatum_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.39933 ONCODG1 CCLE Cell Line Gene CNV Profiles 1.0 1.84449 GSE192870_2_v_0_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null layer 3 of LOT Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.26111 CSTB_KO_GDS5090_398_mouse_cerebella GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null substance dependence GWASdb SNP-Disease Associations 1.0 0.268396 specific developmental disorder GWASdb SNP-Disease Associations 1.0 0.263574 mediodorsal nucleus of thalamus_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.18551 Developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.719 lateral group of nuclei, right, dorsal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06894 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null lateral trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51111 Dentate gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.154 superficial stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10308 outer SZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.895938 BARHL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.1361 HOXB8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.1095 BEN Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.96798 Brain Lower Grade Glioma_LGG_TCGA-FG-A713-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE235945_1_v_0_pikfyve_mouse RummaGEO Gene Perturbation Signatures -1.0 null STAT1::STAT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.2742 496100514_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.74364 SULT2A1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16347 GTEX-Q2AG-0011-R1A-SM-2HMJI GTEx Tissue Sample Gene Expression Profiles 1.0 1.03992 G protein-coupled receptor dimeric complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.999 dentate gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.24076 membrane-bounded vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.984393 mantle zone of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47291 Corpus albicans TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.243 H3K4me3_cardiac mesoderm_hg19_4 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the mouth GWASdb SNP-Phenotype Associations 1.0 0.117078 PHOX2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.0392 SAP30 ENCODE Transcription Factor Targets 1.0 null PPP1R8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44062 GSE181959_3_v_2_dextran_mouse RummaGEO Drug Perturbation Signatures 1.0 null PANC 08.13 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.957685 PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1-FLI1-KDM6B_genes-Genes_associated_to_EWSR1_FLI1-KDM6B_peaks_in_A-673_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null PMC10769395-media-2.xlsx-S2E_EF_Activated_genes-Ebegboni_et_al_Supplemental_Table_S2E_Decreased_expression_following_depletion_of_EWSR1_FLI1_TC-32_TC-71_and_A673_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null RBBP5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null behavioral abnormality GWASdb SNP-Phenotype Associations 1.0 0.186583 GTEX-R55F-0011-R8A-SM-2TF4F GTEx Tissue Sample Gene Expression Profiles 1.0 0.989942 mTert_OE_GDS1211_256_mouse_Embryonic fibroblasts GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EP300 ChEA Transcription Factor Targets 1.0 null Intrinsic component of postsynaptic specialization membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.636 Posterior amygdala TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.554 LONP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.45774 ZMYND11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15982 anterior olfactory area, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01238 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.327581 nitration GeneRIF Biological Term Annotations 1.0 null DBH_KO_GSE33906_53_mouse_heart (E10.5) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K27me3_cardiac mesoderm_hg19_7 ENCODE Transcription Factor Binding Site Profiles 1.0 null Mild cognitive impairment DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.092 Mouse - Motor Cortex - Cluster - Sncg+ GABAergic neuron HuBMAP Azimuth Cell Type Annotations 1.0 null PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-GENE_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null GSE202434,GSE202438_7_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null hypoglossal nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.26325 mantle zone of r6Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32498 DCUN1D3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.07706 temporal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.720345 PMC11801220-NIHMS2038999-supplement-15.xlsx-Exc-SKOR2-gene_SKOR2 Rummagene Transcription Factor Associations 2026 1.0 null CUX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6278 striatum_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.969382 PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2 Rummagene Transcription Factor Associations 2026 1.0 null Human - Motor Cortex - Cross-Species Cluster - Sncg+ GABAergic neuron_4 HuBMAP Azimuth Cell Type Annotations 1.0 null HUP-T4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.865538 IRF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 53.9167 PMC6938365-pone.0226733.s020.txt--ZNF217_ZNF217 Rummagene Transcription Factor Associations 2026 1.0 null basolateral nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17422 DMS53 CCLE Cell Line Gene CNV Profiles -1.0 -1.64754 dentate gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.759086 Viscus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 2.757 NRF1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_KLF4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null FSP27_KO_GDS3768_514_mouse_White adipose tissue (WAT) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.746 H3K27me3_HepG2_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.44826 GTEX-N7MS-2526-SM-2D7W3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.958773 endomembrane system COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K4me3_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null OUMS-23 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.54993 MHHES1 CCLE Cell Line Gene CNV Profiles -1.0 -1.33992 disease GWASdb SNP-Disease Associations 1.0 0.117173 inner plexiform layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.03346 phenotypic abnormality GWASdb SNP-Phenotype Associations 1.0 0.518575 abnormality of the lung GWASdb SNP-Phenotype Associations 1.0 0.588175 mantle zone of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.69903 H3K4me1_iPS DF 19.11 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC4860404-Table1.XLSX-MR_specific-Table_S1-9_DEGspecific_for_mouse_rat_SCI_at_1_dpi_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null EIF2A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.02533 Hypertrophy CTD Gene-Disease Associations 1.0 1.15967 496100577_FWM_probable Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.57575 Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A8O8-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Parietal lobe TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.024 Intrinsic component of cell outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.728 HIPK2_knockout_171_GSE39253 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 0.943727 GSE212772_0_v_1_ncoa4_mouse RummaGEO Gene Perturbation Signatures 1.0 null Rectum adenocarcinoma_READ_TCGA-AH-6903-01A-11R-1928-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ventral posterior inferior nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.933513 Perturb_12619_KO_SF3B1_SRP056033 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 MDA-MB-175-VII COSMIC Cell Line Gene Mutation Profiles 1.0 null BJAB Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2534 GTEX-NPJ7-0011-R6a-SM-2I3G7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.83276 NIH:OVCAR-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3352 ALEXANDERCELLS CCLE Cell Line Gene CNV Profiles -1.0 -2.59447 neuron projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.561772 Human - Tonsil - L2 - IgD PC precursor HuBMAP Azimuth Cell Type Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7470-01A-12R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QMR6-1426-SM-32PLA GTEx Tissue Sample Gene Expression Profiles 1.0 0.900427 PMC12505200-ALZ-21-e70629-s002.docx-3-AA_AD_GWAS_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null EIF4E CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.01205 NCI-H196 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.59607 medial superior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.83026 abnormalities of the peripheral arteries GWASdb SNP-Phenotype Associations 1.0 0.206171 cognitive impairment GWASdb SNP-Phenotype Associations 1.0 0.522136 sensory cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.531089 Dihydropyrimidinase deficiency DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.114 KDM5A ENCODE Transcription Factor Targets 1.0 null GTEX-WWYW-3026-SM-3NB36 GTEx Tissue Sample Gene Expression Profiles 1.0 0.987504 dementia GWASdb SNP-Disease Associations 1.0 0.37017 GTEX-QDT8-0011-R3A-SM-32PKR GTEx Tissue Sample Gene Expression Profiles 1.0 1.08099 TEAD4-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-WHSE-0011-R5A-SM-3P5ZO GTEx Tissue Sample Gene Expression Profiles 1.0 1.52753 FOXP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.2676 HUG1N Achilles Cell Line Gene Essentiality Profiles -1.0 -1.1442 hsa-miR-2115 TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR Rummagene Transcription Factor Associations 2026 1.0 null 20140255-TableS2 GeneSigDB Published Gene Signatures 1.0 null ZR75B Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.16623 hsa-miR-875-3p TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 ZNF292 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10855 lateral part of r6B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56127 inferior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.38189 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1ML-01A-11R-A14Y-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WL46-0011-R6A-SM-3LK6X GTEx Tissue Sample Gene Expression Profiles 1.0 1.25697 H3K27me3_Adipose Nuclei Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE186005_1_v_2_klf5_mouse RummaGEO Gene Perturbation Signatures 1.0 null Uterine Carcinosarcoma_UCS_TCGA-NA-A4QW-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SOX2-22085726-NPCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Presynaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.338 anterior digastric muscle trigeminal motor cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19038 amygdala BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.977601 amyloid GeneRIF Biological Term Annotations 1.0 null GTEX-TSE9-0011-R6A-SM-3DB7L GTEx Tissue Sample Gene Expression Profiles 1.0 1.74584 Dentate gyrus, granule cell layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51556 GSE227698_2_v_0_g0s2_human RummaGEO Gene Perturbation Signatures -1.0 null modulation of chemical synaptic transmission SynGO Synaptic Gene Annotations 1.0 null cerebellar cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.924163 amygdaloid complex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.23076 Hippocampus TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Granule cell layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.875 mantle zone of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37864 Synaptic vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.288 SCRT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4077 GTEX-NL3H-0011-R11A-SM-2I3E6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.1584 ZNF689 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31116 YY1 JASPAR Predicted Transcription Factor Targets 1.0 null PMC6293073-LSA-2018-00153_TableS1.xlsx-A_KD_Tr_1_3_DNAm-Unnamed_1_AR Rummagene Transcription Factor Associations 2026 1.0 null Mesothelioma_MESO_TCGA-LK-A4O6-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE85565_1_v_0_tcf21_human RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_HEK293_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null POU3F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.8039 Medium spiny neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.128 Whole Blood GTEx Tissue Gene Expression Profiles 2023 1.0 5.60829 ADNP_Deficiency - NULL MUTATION_GDS2540_691_mouse_E9 embryos - Heterozygous mutant GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5 Rummagene Transcription Factor Associations 2026 1.0 null BCL2L11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.07302 NB7 DepMap CRISPR Gene Dependency 1.0 2.00342 Cognitive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.77 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.944695 abnormality of the head GWASdb SNP-Phenotype Associations 1.0 0.073558 Human - Motor Cortex - Cross-Species Cluster - Sncg+ GABAergic neuron_3 HuBMAP Azimuth Cell Type Annotations 1.0 null SVGp12 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.706 TEAD4_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF268 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22034 Perturb_13979_KO_Dnmt3a_SRP168393 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 HCC56 CCLE Cell Line Gene Expression Profiles 1.0 1.93133 Sarcoma_SARC_TCGA-SI-AA8C-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null integral component of organelle membrane GO Cellular Component Annotations 2015 1.0 null H3K27me3_H7_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE65617_5_v_1_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null PDE10A_KO_GSE40377_581_mouse_Striatum and hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.899129 NCI-H2228 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.968625 H3K27me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Integral component of postsynaptic density membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.742 Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me3_BE2C_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null binding GO Molecular Function Annotations 2015 1.0 null abnormality of the respiratory system GWASdb SNP-Phenotype Associations 1.0 0.208203 golgi apparatus LOCATE Curated Protein Localization Annotations 1.0 null Olfactory glomerulus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.12 PMC9882185-media-4.xlsx-Neuron_KD-ID_AR Rummagene Transcription Factor Associations 2026 1.0 null superficial stratum of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.16796 Cell body fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.138 HCN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05444 cuneate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.08928 Robust nucleus of arcopallium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.881 hsa-miR-548ad TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 NB13 DepMap CRISPR Gene Dependency 1.0 11.2742 brain TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null MAX_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LAMA2_Deficiency_GDS1778_747_mouse_Diaphragm (from dystrophia muscularis -dy/dy- mouse model) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-P44H-0011-R4A-SM-2XCEW GTEx Tissue Sample Gene Expression Profiles 1.0 0.874251 Presynapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.443 acetylcholine GeneRIF Biological Term Annotations 1.0 null cytoplasmic vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 496100455_FWM_dementia_TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.3708 nucleus subceruleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.874947 abnormality of immune system physiology GWASdb SNP-Phenotype Associations 1.0 0.182414 outer CP in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.22085 vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.867206 GTEX-WVLH-3026-SM-3MJG9 GTEx Tissue Sample Gene Expression Profiles 1.0 0.869876 GTEX-X585-0011-R1B-SM-46MVE GTEx Tissue Sample Gene Expression Profiles 1.0 1.1432 RMUG-S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.824086 nicotine dependence GWASdb SNP-Disease Associations 1.0 0.840288 TMEM243 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.69152 H3K4me3_SK-N-MC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null nutrition disease GWASdb SNP-Disease Associations 1.0 0.369056 AAMP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48098 rostral putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.21534 Mouse - Motor Cortex - Subclass - Vip+ GABAergic neuron HuBMAP Azimuth Cell Type Annotations 1.0 null cerebral hemisphere TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.793543 Perturb_6175_OE_Zeb1_SRP187711 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.83254 nasal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.194837 LCLC103H DepMap CRISPR Gene Dependency 1.0 2.4495 cardiovascular system disease GWASdb SNP-Disease Associations 1.0 0.660239 Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7393-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null immune GAD High Level Gene-Disease Associations 1.0 0.293278 medioventral part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26306 GTEX-T5JC-0011-R7A-SM-32PME GTEx Tissue Sample Gene Expression Profiles 1.0 1.39906 BCL11B_KO_GSE9330_4_mouse_brain (striatum) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null cerebral cortex TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GTEX-T2IS-3026-SM-32QPM GTEx Tissue Sample Gene Expression Profiles 1.0 0.894272 GTEX-WWYW-0011-R11A-SM-3NB38 GTEx Tissue Sample Gene Expression Profiles 1.0 1.25488 CAS1 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.45636 Primary hematopoietic stem cells G-CSF-mobilized Female RO_01480 Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -1.17935 GSE213588_8_v_11_trametinib_human RummaGEO Drug Perturbation Signatures 1.0 null ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.1238 GTEX-T2IS-0011-R11A-SM-32QPC GTEx Tissue Sample Gene Expression Profiles 1.0 1.18758 GSE138001_2_v_3_rorb_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE202434,GSE202438_12_v_14_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null NR2F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5408 EP300_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WZTO-0011-R8A-SM-4E3II GTEx Tissue Sample Gene Expression Profiles 1.0 0.905035 Feather barbules TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.969 DES_KO_GDS4804_171_mouse_young skeletal muscles GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Arciform density COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.579 hindbrain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.236332 GTEX-WL46-0011-R11A-SM-3MJFT GTEx Tissue Sample Gene Expression Profiles 1.0 1.29712 hsa-miR-3121-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.828473 hsa-miR-181b TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 GTEX-T6MN-0011-R7A-SM-32QP5 GTEx Tissue Sample Gene Expression Profiles 1.0 2.04409 RPAP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.48548 gracile nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.18193 GTEX-WZTO-0011-R3B-SM-3NMC6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.03756 COLO 741 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.07604 GTEX-WL46-0011-R2A-SM-3LK6O GTEx Tissue Sample Gene Expression Profiles 1.0 1.51705 hsa-miR-186 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 Nucleus of Roller Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02761 Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null extracellular region part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04435 PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP Rummagene Transcription Factor Associations 2026 1.0 null SK-MEL-24 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.968625 PMC5817105-thnov08p0972s2.xls-SIX3-GeneName_SIX3 Rummagene Transcription Factor Associations 2026 1.0 null SLR26 CCLE Cell Line Gene Expression Profiles -1.0 -1.83439 Vesicle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 hematological neoplasm GWASdb SNP-Phenotype Associations 1.0 0.1379 GTEX-QVJO-0011-R4A-SM-2S1QL GTEx Tissue Sample Gene Expression Profiles 1.0 1.00338 496100470_HIP_possible Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.07676 CORL95 CCLE Cell Line Gene Expression Profiles 1.0 1.47354 genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.045314 POLR2A ENCODE Transcription Factor Targets 1.0 null hsa-miR-4786-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 central nuclear group Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.76191 Amelogenesis imperfecta type 1E DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.69 hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.43404 GTEX-P44H-0011-R5A-SM-2XCEX GTEx Tissue Sample Gene Expression Profiles 1.0 1.84617 GTEX-QMR6-0011-R4A-SM-32PKU GTEx Tissue Sample Gene Expression Profiles 1.0 0.955932 hsa-miR-4687-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 hsa-miR-92a-3p MiRTarBase microRNA Targets 1.0 null hypertension GWASdb SNP-Disease Associations 1.0 0.803948 GTEX-X585-0011-R3B-SM-46MVG GTEx Tissue Sample Gene Expression Profiles 1.0 1.04764 abnormality of the genitourinary system GWASdb SNP-Phenotype Associations 1.0 0.079384 PMC11801220-NIHMS2038999-supplement-15.xlsx-Inh-MEF2C-gene_MEF2C Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-4316 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 GTEX-NPJ8-2626-SM-2D7W2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.881661 GTEX-N7MS-0011-R4a-SM-2HMKW GTEx Tissue Sample Gene Expression Profiles 1.0 0.900928 granular layer of caudal dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.955327 J82 DepMap CRISPR Gene Dependency 1.0 2.23369 IRF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3312 IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.18308 PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Supplemental_Table_6_Genes_downregulated_in_NEUROG3-_-_hESC_line_differentiated_to_pancreatic_endocrine_progenitors_d13_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null CDAN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.53608 mantle zone of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37174 Adolescent Idiopathic Scoliosis DisGeNET Gene-Disease Associations 1.0 null SW 1417 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26597 UACC257 CCLE Cell Line Gene CNV Profiles 1.0 1.82384 GSE160817_7_v_1_slamf6_human RummaGEO Gene Perturbation Signatures -1.0 null PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null upper (rostral) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.959533 Retrosplenial region TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.072 Fibre tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.835 Reading disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.17 striatum_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0038 GSE160077,GSE160084_3_v_0_bin1_mouse RummaGEO Gene Perturbation Signatures 1.0 null H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH446 CCLE Cell Line Gene Expression Profiles 1.0 1.71535 ZSCAN16 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.1334 H3K27me3_endothelial cell of umbilical vein_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7874-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null disease of mental health GWASdb SNP-Disease Associations 1.0 0.21612 epidermis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067139 GTEX-XOTO-0011-R5A-SM-4B657 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0167 obesity GWASdb SNP-Phenotype Associations 1.0 0.512746 GTEX-X261-0011-R11A-SM-4E3JY GTEx Tissue Sample Gene Expression Profiles 1.0 1.2991 PMC8905236-mmc2.xlsx-Table_S10-Table_S10_Differentially_regulated_genes_in_SPI1_high_vs_low_group_in_CGGA_GBM_dataset_SPI1 Rummagene Transcription Factor Associations 2026 1.0 null outer SZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.937412 coronary artery disease GWASdb SNP-Phenotype Associations 1.0 0.468662 Rod spherule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.674 Subiculum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.444 NR4A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.0159 hippocampus (hippocampal formation)_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.898051 cdna GeneRIF Biological Term Annotations 1.0 null abnormality of taste sensation GWASdb SNP-Phenotype Associations 1.0 0.429949 bronchoalveolar system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.079837 GTEX-N7MT-0011-R7a-SM-2I3FZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.15222 cerebellar cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.02312 PMC10591879-NIHMS1933918-supplement-2.xlsx-Down_in_NMR_OPC_differentiation-EGR1_EGR1 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-2113 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 abnormal emotion/affect behavior GWASdb SNP-Phenotype Associations 1.0 0.307634 H413 DepMap CRISPR Gene Dependency 1.0 3.31634 caudal portion of VFC (area 44) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.34333 GTEX-X585-0011-R6A-SM-46MVJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.91868 Postcentral gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.167 CHD2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 496100277_FWM_no dementia_no TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.37258 intermediate (interpositus) cerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.6649 Olfactory ensheathing cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.703 H3K4me1_limb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null synapse part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GTEX-RNOR-0011-R4A-SM-3GAD3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.855664 synaptic vesicle membrane GO Cellular Component Annotations 2015 1.0 null GTEX-WZTO-0011-R10B-SM-4E3KB GTEx Tissue Sample Gene Expression Profiles 1.0 0.987534 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null JNK_KO_GDS3001_531_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-01A-11R-2016-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Axon COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.052 cerebellum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.895841 MDA-MB-436 COSMIC Cell Line Gene Mutation Profiles 1.0 null KPL1 DepMap CRISPR Gene Dependency 1.0 8.00287 striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10163 orbital frontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.36269 amygdaloid complex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.838167 Inflammation CTD Gene-Disease Associations 1.0 1.09083 motor nucleus of trigeminal nerve, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.930929 Fiber TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.962 NANOG-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null 496100362_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.27207 medial group of nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.0616 A673 CCLE Cell Line Gene CNV Profiles -1.0 -1.35708 SOX2 ChEA Transcription Factor Targets 1.0 null GSE162590_1_v_0_gsx2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null cerebellar cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.55481 H3K27me3_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68D-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 immunologic hypersensitivity GWASdb SNP-Phenotype Associations 1.0 0.321159 GTEX-UTHO-0011-R5A-SM-3GIJD GTEx Tissue Sample Gene Expression Profiles 1.0 2.04416 Mitral cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.131 breast cancer GWASdb SNP-Disease Associations 1.0 1.47579 hsa-miR-944 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 GTEX-XOTO-0011-R6B-SM-4B65X GTEx Tissue Sample Gene Expression Profiles 1.0 1.31015 PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-female_port-FOS_1_FOS Rummagene Transcription Factor Associations 2026 1.0 null Lung squamous cell carcinoma_LUSC_TCGA-22-5483-01A-01R-1820-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GABA-ergic synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.431 facial motor nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.42021 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.21835 MITF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.8482 Postsynaptic specialization COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.59 HDAC6_KO_GDS4375_532_mouse_Foxp3(+) Tregs GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null intracellular COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 cell part LOCATE Predicted Protein Localization Annotations 1.0 null PMC6938365-pone.0226733.s018.txt--GATA2_GATA2 Rummagene Transcription Factor Associations 2026 1.0 null PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1 Rummagene Transcription Factor Associations 2026 1.0 null r4 part of medial pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1893 Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.32 cerebellar cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.824868 Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4858-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02599 PMC10714175-mmc2.xlsx-KD_Gene_list-Unnamed_2_AR Rummagene Transcription Factor Associations 2026 1.0 null JUND ENCODE Transcription Factor Targets 1.0 null GSE101239_4_v_2_valproic acid_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE242199_9_v_5_ntrk2_human RummaGEO Gene Perturbation Signatures 1.0 null STK10 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54822 GSE129241_4_v_2_valproic acid_human RummaGEO Drug Perturbation Signatures 1.0 null DAOY CCLE Cell Line Gene Expression Profiles -1.0 -1.69646 hsa-miR-4699-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 OUMS23 CCLE Cell Line Gene Expression Profiles 1.0 1.3927 Epithalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40318 Weight Loss CTD Gene-Disease Associations 1.0 1.15899 H3K27me3_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE234289_5_v_2_rfx6_human RummaGEO Gene Perturbation Signatures 1.0 null central nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.35663 dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.53856 intracellular membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 KM12 CCLE Cell Line Gene Expression Profiles 1.0 1.89937 H3K4me3_SK-N-SH_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null retina TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.574816 Smooth endoplasmic reticulum cisterna COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.503 ABCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.61281 head of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.50278 mediodorsal nucleus of thalamus_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.09982 GSE219195_1_v_5_rbm12_human RummaGEO Gene Perturbation Signatures 1.0 null AOB, outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.98867 PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-T5JC-0011-R10A-SM-32PM2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.971379 mediodorsal nucleus of thalamus_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0161 H3K27me3_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null hsa-miR-4262 TargetScan Predicted Conserved microRNA Targets 1.0 1.45615 Synaptic vesicle lumen COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.58 HNF4 MotifMap Predicted Transcription Factor Targets 1.0 null clathrin-coated vesicle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 SOX2-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null pontine nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.49784 Brain Lower Grade Glioma_LGG_TCGA-HT-7688-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14776_KO_Tsc2_SRP227934 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 10.1399 external granular (germinal) layer of lower rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.86977 depression GWASdb SNP-Phenotype Associations 1.0 0.389633 GGCT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.32591 FLI1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Targets 2022 1.0 null disease of metabolism GWASdb SNP-Disease Associations 1.0 0.34519 r7 part of the dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26286 Perturb_8901_KD_STIM1_SRP128928 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 3.20729 PMC8528285-pbio.3001085.s010.xlsx-Fig_S8A-MLX_3T3_MLX Rummagene Transcription Factor Associations 2026 1.0 null KLE CCLE Cell Line Gene Expression Profiles 1.0 1.57934 SK-MEL-28 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.98087 Specific language impairment DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.669 GTEX-Q2AG-0011-R3A-SM-2HMJ9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0564 PMC3906982-1471-2164-14-830-S1.xlsx-Sheet1-Table_S1_HOXC9-responsive_genes_HOXC9 Rummagene Transcription Factor Associations 2026 1.0 null 496100494_HIP_no dementia_TBI_100+_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.3201 MDAMB415 CCLE Cell Line Gene CNV Profiles -1.0 -1.93136 medial trapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20451 GTEX-WVLH-0011-R4A-SM-3MJFS GTEx Tissue Sample Gene Expression Profiles 1.0 0.956326 tyrosine GeneRIF Biological Term Annotations 1.0 null CDX2-19796622-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-GENE_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null medial (fastigial) cerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08142 NRL_Deficiency_GDS1693_237_mouse_Photoreceptors cells of retinas at P6 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Mouse - Motor Cortex - Cluster - Vip+ Mybpc1+ GABAergic neuron_2 HuBMAP Azimuth Cell Type Annotations 1.0 null LN382 CCLE Cell Line Gene Expression Profiles -1.0 -1.75772 endoplasmic reticulum LOCATE Curated Protein Localization Annotations 1.0 null MCF7 CCLE Cell Line Gene CNV Profiles 1.0 2.88944 EP300-20729851-FORBRAIN-MIDBRAIN-LIMB-HEART-MOUSE ChEA Transcription Factor Targets 2022 1.0 null inner SZ in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.05488 PMC12126244-jci-135-184115-s239.xlsx-Table_3_Suppl_Fig_16-Genes_down-regulated_in_SOX9_low_tumors_744_genes_SOX9 Rummagene Transcription Factor Associations 2026 1.0 null layer IIIu of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.915106 caudal (posterior) extramural migratory stream Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.84088 Perturb_4473_KO_Prdm12_SRP304476 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 2.7241 YMB-1-E COSMIC Cell Line Gene Mutation Profiles 1.0 null GATA3 ENCODE Transcription Factor Targets 1.0 null TCF4-23295773-U87-HUMAN ChEA Transcription Factor Targets 2022 1.0 null DMS454 CCLE Cell Line Gene CNV Profiles -1.0 -1.82672 head TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null r6 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19689 ZNF652 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.1119 r6 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.88153 GTEX-X585-0011-R8A-SM-46MUX GTEx Tissue Sample Gene Expression Profiles 1.0 0.831016 Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZF-01A-11R-A23N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null 888 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32965 GSE92457_9_v_12_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null IPC-298 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.42855 Cell outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.684 overnutrition GWASdb SNP-Disease Associations 1.0 0.436942 Perturb_918_KD_BC200_SRP261125 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -17.7399 inherited metabolic disorder GWASdb SNP-Disease Associations 1.0 0.298675 PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-GENE_DBP Rummagene Transcription Factor Associations 2026 1.0 null bounding membrane of organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.00417 layer 1 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.35939 Olfactory receptor neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.326 striatum_19 yrs_F_12832 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.41605 OLIG2 ChEA Transcription Factor Targets 1.0 null respiratory system disease GWASdb SNP-Disease Associations 1.0 0.34113 SNX2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10104 coated vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.801562 PMC7608835-aba3058_Table_S4.xlsx-EWS-FLI1_RING1B-Genes_containing_RING1B_EWSR1-FLI1_enhancers_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null neuron part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.794 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.44404 Depressive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.388 PMC8387919-mmc2.xlsx-ST8_NEUROG3_and_islets_expr-Unnamed_2_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null Perihypoglossal nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03585 neurological GAD High Level Gene-Disease Associations 1.0 0.293278 Synaptophysin/synaptoporin InterPro Predicted Protein Domain Annotations 1.0 null A_CA_04_2009_7dayMOI-10^3_None_GSE37569 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.59845 NR3C2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.18746 Pancreatic adenocarcinoma_PAAD_TCGA-3E-AAAY-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Smoking Behaviors DisGeNET Gene-Phenotype Associations 1.0 null tic disorder GWASdb SNP-Disease Associations 1.0 0.688771 TSACC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.8758 PRMT6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.62194 Zona incerta TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.88 hsa-miR-509-3-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Synaptic vesicle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 H4K20me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null POU5F1-26923725-CHIP-SEQ-MESODERM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null LTV1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.15946 acute lymphocytic leukemia GWASdb SNP-Disease Associations 1.0 0.516361 ADD3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.36906 Prelimbic area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.065 MKN45 DepMap CRISPR Gene Dependency 1.0 2.97797 Agranular insular cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.972 hsa-miR-3647-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.212286 CDX2-19796622-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null SRSF5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.70627 H3K4me3_cardiac mesoderm_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null COLO 699 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14724 BICR 22 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13779 ENC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.43372 r2 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37797 mantle zone of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28193 GSE210101,GSE210114_2_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null KDM4A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29Q-06A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null periventricular stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.47592 JMJD8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08865 GSE216147_2_v_1_rbm20_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE184902_4_v_0_adipor1_mouse RummaGEO Gene Perturbation Signatures 1.0 null periventricular stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04163 SMAD4-21799915-A2780-HUMAN ChEA Transcription Factor Targets 2022 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.2108 Cornu ammonis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.836 PPARA::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.3627 cerebellar cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.83254 POU2F2 JASPAR Predicted Transcription Factor Targets 1.0 null Perturb_14013_KO_Perk_SRP370072 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 Cerebellar cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.482 H3K27me3_liver_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r4 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70854 Excitatory synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.527 Embryonic brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.018 CSTB_KO_GDS5090_199_mouse_Cerebellum GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GSE68156_3_v_4_dextran_mouse RummaGEO Drug Perturbation Signatures 1.0 null XRCC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.86881 Hypothalamus TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.764 PMC7438927-Table_2.XLSX-upregulated_in_AA-Upregulated_in_AA_Log2FC_3_Adjusted_P_value_0_01_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null GSE120370_0_v_3_thrombin_mouse RummaGEO Drug Perturbation Signatures 1.0 null LTBR_INHIBITION - 2 Days_GDS2004_734_mouse_Lymph nodes (MG-430A) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null abnormality of blood and blood-forming tissues GWASdb SNP-Phenotype Associations 1.0 0.045937 Transport vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.491 asymmetric synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.324201 alzheimer's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.28616 RECQL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.17909 GSE210101,GSE210114_2_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null premotor cortex (area 6) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.924349 GTEX-R55E-0011-R7A-SM-2TC5Z GTEx Tissue Sample Gene Expression Profiles 1.0 1.12307 Cerebral cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.212 GSU CCLE Cell Line Gene CNV Profiles 1.0 1.77465 bipolar disorder GWASdb SNP-Disease Associations 1.0 0.809109 HEC-1-A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33161 integral component of synaptic vesicle membrane GO Cellular Component Annotations 2015 1.0 null GTEX-R55F-0011-R6A-SM-2TF4L GTEx Tissue Sample Gene Expression Profiles 1.0 1.74822 cell part GO Cellular Component Annotations 2015 1.0 null LTBR_INHIBITION - 27 Day_GDS2004_736_mouse_Lymph nodes (MG-430A) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H3K4me3_ES-E14_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null CTCF_small intestine_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null peripheral nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.293151 GTEX-TSE9-2926-SM-3DB77 GTEx Tissue Sample Gene Expression Profiles 1.0 0.962997 GTEX-WZTO-0011-R11A-SM-4E3K9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13557 H3K23me2_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null limbic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.793543 Supplemental somatosensory area, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0104 magnesium GAD Gene-Disease Associations 1.0 null H3K4me3_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null orbital frontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.9531 RAB38 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44211 NT5C3B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.08114 CHD7 ENCODE Transcription Factor Targets 1.0 null dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.14945 striatum_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.98352 superficial stratum of r2Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05992 GSE195559_6_v_7_notch1_human RummaGEO Gene Perturbation Signatures 1.0 null photoreceptor TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.396465 GSE146687_2_v_0_eribulin_human RummaGEO Drug Perturbation Signatures -1.0 null RPS13 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64116 primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.28932 Autosomal dominant disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.033 Scolopidium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.043 ETV2::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.4985 synaptic vesicle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -2.27383 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ebolavirus(ZEBOV)_7day_PBMCs_rNAPc2treated_21987740_GSE24943 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 0.210854 BCL11B_KO_GDS3178_296_mouse_striatum GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null intracellular membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.427104 ID1_01_117 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 4.38559 GTEX-N7MS-0011-R10A-SM-2HMJK GTEx Tissue Sample Gene Expression Profiles 1.0 0.908265 PMC8387919-mmc2.xlsx-ST6_NEUROG3-KO_downreg-Unnamed_4_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null KMS-11 COSMIC Cell Line Gene Mutation Profiles 1.0 null GTEX-S7SE-0011-R5A-SM-2XCDA GTEx Tissue Sample Gene Expression Profiles 1.0 1.4164 Oligospermia CTD Gene-Disease Associations 1.0 1.03864 OLIG2-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null TAL1-21186366-BM-HSCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null tauopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.284728 nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.943935 GTEX-QVJO-1325-SM-2S1QX GTEx Tissue Sample Gene Expression Profiles 1.0 0.889559 GSE178113,GSE178116_0_v_1_atrx_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K27me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null ESR1_KD_GDS4065_452_human_MCF7 estrogen-sensitive breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null coronary artery disease GWASdb SNP-Disease Associations 1.0 0.549587 Liver BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.17967 DUX4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.9922 posteroventral (inferior) parietal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00267 SARS-CoV MA15_Day4-PFU-10^5_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.78695 cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.950072 HS 578T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.853691 Granular lamina of the cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01608 H2AFZ_mammary epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null LHFPL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35185 FLI1::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.2222 Fasciolar gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.794 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7418-01A-11R-2081-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP Rummagene Transcription Factor Associations 2026 1.0 null H3K4me3_SK-N-MC_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null paravermis of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.877282 GLIS3_KO_GDS3812_500_mouse_Embryonic pancreas at E15.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null SMIM24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4115 NCIH810 CCLE Cell Line Gene CNV Profiles -1.0 -1.68321 Inner plexiform layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.184 molecular layer of the DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37412 GSE210101,GSE210114_4_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null keratinocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.113085 POU5F1-16153702-HESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null ETV2::DRGX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.4305 Autism GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.530103 cytoplasmic vesicle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 SNU-C1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01646 Caudolateral nidopallium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.746 striatum_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.14059 496100436_FWM_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -4.16395 calcium- and calmodulin-dependent protein kinase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.311 embryo TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.098643 KPL1 CCLE Cell Line Gene CNV Profiles 1.0 2.45191 GSE94011_2_v_1_pias3_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me3_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null neurodegenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.084339 PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-OLIG2_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_OLIG2 Rummagene Transcription Factor Associations 2026 1.0 null ZNF526 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1192 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null arcuate nucleus of medulla, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.56248 NCI-H2810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05893 Chromosomal disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.064 SW1710 CCLE Cell Line Gene Expression Profiles -1.0 -1.98643 FOXO1::ELK3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.9196 Piriform area TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.019 Brain stem TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.509 Ebolavirus(EBOV)_3day_Splenocytes_19683682_GSE17509 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.84911 PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_13_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null Cochlear nucleus, subpedunclular granular region Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23567 attention deficit hyperactivity disorder GWASdb SNP-Disease Associations 1.0 0.688771 striatum_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.958292 Juxtaglomerular cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.004 axon terminus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.377738 H3K4me3_cardiac mesoderm_hg19_6 ENCODE Histone Modification Site Profiles 1.0 null POLR2A_limb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45244 VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.55678 interneuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.586828 r3 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.69714 NANOG-16153702-HESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null OV-90 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09784 PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null PHOX2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.1382 GSE189859,GSE189861_4_v_2_idh1_human RummaGEO Gene Perturbation Signatures -1.0 null anterior olfactory area, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08208 cerebellar cortex_21 pcw_M_12886 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.44918 Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cranial nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.135083 OC314 DepMap CRISPR Gene Dependency 1.0 2.10013 HOOK2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.1245 r5 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04253 BT20 CCLE Cell Line Gene CNV Profiles 1.0 1.59021 H3K27me3_brain_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.16701 GSE210101,GSE210114_4_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null CAL 27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.880769 granule cell layer of the DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51119 intermediate stratum of DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39597 Perisynaptic space COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.534 Neuroendocrine cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.147 anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.850284 Main olfactory bulb, mitral layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80474 GTEX-T5JC-0011-R1A-SM-32PM6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.16444 Psychotic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.617 dexamethasone_homo sapiens_gpl6244_gse20963 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Granular vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.137 intracellular membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.397811 OAW42 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.00828 striatum_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.851958 U178 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.16757 periventricular stratum of r4Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.70854 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IF-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.042391 Hippocampal mossy fiber TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.191 H3K4me3_MCF-7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null trans-Golgi network membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.496 dentate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.17096 KMS-28PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.96798 Small Intestine - Terminal Ileum GTEx Tissue Gene Expression Profiles 2023 1.0 1.24374 mantle zone of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23398 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MU-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ganglion cell layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.452969 intracellular organelle part GO Cellular Component Annotations 2015 1.0 null FOXK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7585 18381423-Table1 GeneSigDB Published Gene Signatures 1.0 null hsa-miR-671-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 SIN3A ENCODE Transcription Factor Targets 1.0 null E2F6 ENCODE Transcription Factor Targets 1.0 null GTEX-N7MS-0011-R7a-SM-2HMKN GTEx Tissue Sample Gene Expression Profiles 1.0 0.867069 VMRCRCW DepMap CRISPR Gene Dependency 1.0 2.81187 GSE206093,GSE206094_1_v_3_isl1_mouse RummaGEO Gene Perturbation Signatures 1.0 null Accessory olfactory bulb, mitral layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.16798 NCIH2227 CCLE Cell Line Gene Expression Profiles 1.0 1.35467 Mouse - Motor Cortex - Cluster - Opalin+ oligodendrocyte_3 HuBMAP Azimuth Cell Type Annotations 1.0 null GSE249714_0_v_1_anxa1_mouse RummaGEO Gene Perturbation Signatures -1.0 null obsessive-compulsive disorder GWASdb SNP-Disease Associations 1.0 0.688771 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null A3/KAW Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.45926 496100543_FWM_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.84055 H3K27me3_kidney epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormal respiratory system morphology GWASdb SNP-Phenotype Associations 1.0 0.246911 GTEX-QDT8-0011-R5A-SM-32PKN GTEx Tissue Sample Gene Expression Profiles 1.0 1.00908 IRF5 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.3234 medial group of nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01132 spleen GTEx Tissue Gene Expression Profiles -1.0 -1.16781 limitans nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.871294 GSE183994_3_v_0_scml2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Human - Motor Cortex - Cluster - SST+ DEFB108B+ Layer 1 GABAergic neuron HuBMAP Azimuth Cell Type Annotations 1.0 null ADGRB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.64942 GSE137914_0_v_1_tet3_mouse RummaGEO Gene Perturbation Signatures 1.0 null synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.03179 striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18015 Spine synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.805 Perturb_5387_KO_Isl1_SRP380182 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.86962 GSE173262_6_v_0_ash1l_mouse RummaGEO Gene Perturbation Signatures -1.0 null Paragigantocellular reticular nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04918 Cmah_KO_GDS4770_421_mouse_muscle GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null MKN74 CCLE Cell Line Gene CNV Profiles -1.0 -3.21049 GTEX-WHSE-0011-R11A-SM-3P5YY GTEx Tissue Sample Gene Expression Profiles 1.0 1.17195 abnormality of body weight GWASdb SNP-Phenotype Associations 1.0 0.318996 mRNA_GATA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null clathrin-coated vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.30121 SMDT1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.51844 anterior part of Int Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45099 VZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14069 external part of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.84091 CAPAN1 CCLE Cell Line Gene CNV Profiles 1.0 1.43105 neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.02995 Asthma dbGAP Gene-Trait Associations 1.0 0.27422 Autistic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.451 increased body weight GWASdb SNP-Phenotype Associations 1.0 0.512746 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5889-01A-11R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QVJO-0011-R6A-SM-2S1QN GTEx Tissue Sample Gene Expression Profiles 1.0 2.00475 substance-related disorder GWASdb SNP-Disease Associations 1.0 0.161697 KDM4A ENCODE Transcription Factor Targets 1.0 null inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.88926 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-WHSE-3026-SM-3P5ZH GTEx Tissue Sample Gene Expression Profiles 1.0 0.827304 posteroventral (inferior) parietal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.44469 SW 1463 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.919568 NIHOVCAR3 CCLE Cell Line Gene CNV Profiles 1.0 1.9638 PMC8919059__F5 PFOCR Pathway Figure Associations 2024 1.0 null NKX6-2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.2924 M-1 BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.982493 metabolic GAD High Level Gene-Disease Associations 1.0 0.295739 ZNF808 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03297 r2 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0056 Arcopallium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.245 gracile nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.13536 temporal lobe TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Zollinger-Ellison syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.042 COLO 794 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.12138 GTEX-QDT8-0011-R2A-SM-32PKQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.991557 dorsorostral division of MFC (area 32) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24955 PMC5325343-oncotarget-07-63003-s002.xlsx-Supplementary_Table_1-Supplementary_Table_1_Genes_upregulated_by_EWS-FLI1_in_the_Gordon_et_al_data_set_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null SPC24 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.05379 Pontine gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.59028 PMC7550584__F3 PFOCR Pathway Figure Associations 2023 1.0 null Ventral pallidus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.76518 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LB-01A-11R-A24H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-RU72-0011-R8A-SM-2TF61 GTEx Tissue Sample Gene Expression Profiles 1.0 0.964661 Dense core granule COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.393 Dentate gyrus HICAP cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.093 SREBF1 JASPAR Predicted Transcription Factor Targets 1.0 null striatum_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.77535 Perturb_6234_KO_Mecp2_SRP045354 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 OVCAR-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.909258 MEIS1-26253404-OPTIC-CUPS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-XOTO-0011-R3A-SM-4B64W GTEx Tissue Sample Gene Expression Profiles 1.0 0.939361 GSE93674_2_v_3_ezh2_mouse RummaGEO Gene Perturbation Signatures 1.0 null CEBPB CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24138 posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.876217 SMAD4 ChEA Transcription Factor Targets 1.0 null OUMS23 CCLE Cell Line Gene CNV Profiles -1.0 -1.54927 HOXD9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.3218 COV413B Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.862998 TRIM28-17542650-NTERA2-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null hsa-miR-146a TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 AGXT2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22849 PMC12311841-CTM2-15-e70424-s001.pdf-16-EMX2-like_EMX2 Rummagene Transcription Factor Associations 2026 1.0 null dentate gyrus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.09361 H3K27ac_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WWYW-0011-R1A-SM-3TW8G GTEx Tissue Sample Gene Expression Profiles 1.0 0.893589 Neuropil TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.357 UACC62 DepMap CRISPR Gene Dependency 1.0 3.69873 Urinary tract TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.946 GSE135352_6_v_4_napabucasin_human RummaGEO Drug Perturbation Signatures -1.0 null membrane-bounded organelle LOCATE Curated Protein Localization Annotations 1.0 null GSE133087_5_v_0_metformin_human RummaGEO Drug Perturbation Signatures -1.0 null hippocampus (hippocampal formation)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.90029 GTEX-XLM4-3026-SM-4AT6L GTEx Tissue Sample Gene Expression Profiles 1.0 0.898478 head TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 Lung adenocarcinoma_LUAD_TCGA-55-7570-01A-11R-2039-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K27me3_CD14-positive monocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QMR6-0011-R7A-SM-32PKL GTEx Tissue Sample Gene Expression Profiles 1.0 0.886033 hsa-miR-4710 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 neurosecretory vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.542352 H3K4me3_HEK293_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null hsa-miR-491-3p TargetScan Predicted Conserved microRNA Targets 1.0 0.90397 GSE196199_0_v_1_zbtb20_mouse RummaGEO Gene Perturbation Signatures 1.0 null PRPF4B CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.29125 GTEX-T5JC-2426-SM-3NMDB GTEx Tissue Sample Gene Expression Profiles 1.0 0.82929 nidopallium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.745864 dorsalrootganglion BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.46784 GTEX-WVLH-0011-R6A-SM-3MJFZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.51351 Motor nucleus of trigeminal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16518 cuneate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.20051 H2AC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.74825 BACH1 ENCODE Transcription Factor Targets 1.0 null LXFL529 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33455 imidazoleglycerol-phosphate synthase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.912 NEUROG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.0754 GSE157555,GSE157556_4_v_2_foxa2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Dentate gyrus mossy fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.902 PMC4042849-rsob-4-140029.pdf-4-P53_TP53 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-NL3H-0011-R6a-SM-2I3G8 GTEx Tissue Sample Gene Expression Profiles 1.0 2.06533 PMC6938365-pone.0226733.s018.txt--POU5F1_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null SCA1_Knock-in_GDS3544_562_mouse_Cerebellum - 12 Weeks GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null MELHO DepMap CRISPR Gene Dependency 1.0 3.63017 temporal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.56716 habenula (old epithalamus) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37078 retina TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null organelle membrane GO Cellular Component Annotations 2015 1.0 null H3K4me3_Fetal Brain Roadmap Epigenomics Histone Modification Site Profiles 1.0 null olfactory tubercle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.49348 pontobulbar body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.29457 H3K4me3_SK-N-SH_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Kidney Chromophobe_KICH_TCGA-KL-8324-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4698 TargetScan Predicted Conserved microRNA Targets 1.0 0.714812 PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT Rummagene Transcription Factor Associations 2026 1.0 null type 2 diabetes mellitus GWASdb SNP-Disease Associations 1.0 1.64031 H3K27me3_cardiac mesoderm_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null H3K27ac_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Autism spectrum disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.602 Transport vesicle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 Bed nuclei of the stria terminalis, anterior division, oval nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.21315 Mouse - Motor Cortex - Cluster - Vip+ Mybpc1+ GABAergic neuron_1 HuBMAP Azimuth Cell Type Annotations 1.0 null Perturb_4159_KO_Mir137_SRP072457 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 11.0505 hsa-miR-3183 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 alzheimer's disease GWASdb SNP-Disease Associations 1.0 0.665868 membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.250751 Subpallium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.195 PK-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04705 hippocampus (hippocampal formation)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.864038 Tectum mesencephali TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.684 Endopeduncular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.56 DMS 53 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.99557 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.693 beta GeneRIF Biological Term Annotations 1.0 null body of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04217 hsa-miR-4698 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A764-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AOB, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.46874 H3K27me3_bronchial epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QMR6-0011-R5A-SM-32PKT GTEx Tissue Sample Gene Expression Profiles 1.0 1.14366 cardiovascular GAD High Level Gene-Disease Associations 1.0 0.293278 PMC6938365-pone.0226733.s018.txt--ZNF217_ZNF217 Rummagene Transcription Factor Associations 2026 1.0 null GSE65617_0_v_1_aire_mouse RummaGEO Gene Perturbation Signatures 1.0 null Calyx of Held COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.656 Acute Myeloid Leukemia_LAML_TCGA-AB-2911-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MHHES1 CCLE Cell Line Gene Expression Profiles 1.0 2.04753 macromolecular complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040295 medial mammillary nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.01398 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE210101,GSE210114_8_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null olfactory epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.217346 GTEX-T5JC-0011-R5A-SM-32PLK GTEx Tissue Sample Gene Expression Profiles 1.0 1.38423 HUPT4 CCLE Cell Line Gene CNV Profiles 1.0 1.6444 asthma GAD Gene-Disease Associations 1.0 null neoplasm of the breast GWASdb SNP-Phenotype Associations 1.0 1.31194 LUZP1-20508642-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Epilepsy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.926 Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE5786 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.86839 PMC6713698-109_2019_1809_MOESM2_ESM.xlsx-AR-PCOS-Gene_List_AR Rummagene Transcription Factor Associations 2026 1.0 null GSE197850_4_v_0_glucagon_human RummaGEO Drug Perturbation Signatures 1.0 null Striate cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.835 LAMA84 Achilles Cell Line Gene Essentiality Profiles 1.0 1.18482 abnormality of nervous system physiology GWASdb SNP-Phenotype Associations 1.0 0.169626 OB granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.96009 outer CP in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.21225 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A556-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RFX5_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE223008_4_v_8_calhm6_mouse RummaGEO Gene Perturbation Signatures 1.0 null ARHGAP12 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.52909 GSE142684_4_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null TBX2-35687133-MCF-7-HUMAN-BREASTCANCER ChEA Transcription Factor Targets 2022 1.0 null GTEX-UTHO-0011-R4A-SM-3GIJP GTEx Tissue Sample Gene Expression Profiles 1.0 1.26006 Neuronal dense core vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.675 Perturb_17679_KO_l2LsL_SRP228817 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Olfactory nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.884 LBHD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.55817 TNKS_INHIBITION_GDS5029_281_human_SW480 KRAS-mutant colorectal cancer cell line - 16hours GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GTEX-QVJO-0011-R1A-SM-2S1QI GTEx Tissue Sample Gene Expression Profiles 1.0 0.825327 CCAR2_02_86 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.49185 ventral pallium Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38405 inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12820 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.874974 GTEX-Q2AG-0011-R11A-SM-2HMKZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.17151 Monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.15 Retina TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 animal TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null PMC7415402-oncotarget-11-2995-s004.xlsx-EWS-FLI1_Type_1_vs_Type_3-Gene_Symbol_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null SUM102PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.998146 glucose metabolism disease GWASdb SNP-Disease Associations 1.0 0.454501 synaptic vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.22568 organelle LOCATE Curated Protein Localization Annotations 1.0 null GSE137818_3_v_7_brca2_mouse RummaGEO Gene Perturbation Signatures 1.0 null AGS CCLE Cell Line Gene Expression Profiles 1.0 1.87561 GSE79663_2_v_0_tcf4_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K4me3_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Auditory cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.852 H3K27me3_BJ_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null mRNA_DNMT3B_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null telencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null SCRT2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.6186 r3 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12655 MITF-21258399-MELANOMA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GTEX-T5JC-0011-R8A-SM-32PLM GTEx Tissue Sample Gene Expression Profiles 1.0 0.911317 abnormality of the tongue GWASdb SNP-Phenotype Associations 1.0 0.429949 striatum_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.87305 GSE189653,GSE203344_2_v_1_fluoxetine_mouse RummaGEO Drug Perturbation Signatures -1.0 null PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaDadj_vs_NC-Gene_ERG Rummagene Transcription Factor Associations 2026 1.0 null NCI-H810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82183 layer 1 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38692 HDAC6_KO_GDS4375_372_mouse_CD4+CD25+ T-regulatory cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null anxiety disorder GWASdb SNP-Disease Associations 1.0 0.32351 raphe nuclei of medulla Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.46252 MYB JASPAR Predicted Transcription Factor Targets 1.0 null GSE203308_9_v_3_brf1_mouse RummaGEO Gene Perturbation Signatures 1.0 null cerebellar cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.838052 Nucleus prepositus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02247 Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8637-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null H3K4me1_brown adipose tissue_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-WZTO-0011-R4A-SM-3NMC7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.867082 GSE210101,GSE210114_5_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null Synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.399 Orbital area, ventrolateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52008 Parahippocampal gyrus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.59 SOX2-21211035-LN229_GBM-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null brain TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 496100562_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.67624 GTEX-XMD1-0011-R10A-SM-4AT4A GTEx Tissue Sample Gene Expression Profiles 1.0 0.908529 STAT6 MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-RU72-2926-SM-2TF66 GTEx Tissue Sample Gene Expression Profiles 1.0 1.12523 Accessory olfactory bulb, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.53064 epithalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.182509 abnormality of head or neck GWASdb SNP-Phenotype Associations 1.0 0.073558 Smith-Magenis syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.14 VZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.903333 intermediate stratum of r6Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19854 Perturb_13974_KO_SYTL3_ERP126655 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 -20.0 GTEX-S7SE-0011-R4A-SM-2XCDB GTEx Tissue Sample Gene Expression Profiles 1.0 0.855543 Necrosis CTD Gene-Disease Associations 1.0 1.03197 H3K4me3_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null ELOVL4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06291 inner CP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.898073 mRNA_NR0B1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null 496100322_FWM_possible Alzheimer's disease_no TBI_100+_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.40134 496100317_FWM_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.74468 intermediate stratum of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.75106 TBP_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCI-H441 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.60018 Subiculum, dorsal part, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00841 superficial stratum of r6BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51506 GSE247764_5_v_2_nell2_mouse RummaGEO Gene Perturbation Signatures -1.0 null mRNA_ETV3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null GTEX-QMR6-0011-R8A-SM-32PKJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.02475 anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.16353 Internal plexiform layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.694 IKZF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.249 GTEX-N7MT-0011-R6a-SM-2I3G3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.58646 HOXD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.05329 hsa-miR-515-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8062-01A-11R-2213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC10714175-mmc2.xlsx-KD_Gene_list-Supplemental_Table_3_FAM13B_knockdown_mediated_changes_in_gene_expression_AR Rummagene Transcription Factor Associations 2026 1.0 null Nutritional optic neuropathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.042 striatum_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.841819 RAD21_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null STAT3 JASPAR Predicted Transcription Factor Targets 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8558-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null basal ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.094342 superficial stratum of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0808 anterior group of nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.39779 SKMEL28 CCLE Cell Line Gene CNV Profiles 1.0 2.23798 Postsynapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.772 SUGP1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.58987 dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.32298 coated vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.26392 C2orf15 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27935 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 fiber TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.783141 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5694-11A-01R-1541-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null intracellular part GO Cellular Component Annotations 2015 1.0 null SW1783 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC1263 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01646 Central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 embryonic structure TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.0842 CADOES1 CCLE Cell Line Gene Expression Profiles 1.0 1.60759 EZH2_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NCIH441 CCLE Cell Line Gene CNV Profiles 1.0 1.516 membrane-bounded organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K4me3_ES-Bruce4_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null FOXP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0414 H3K4me3_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XP-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR Rummagene Transcription Factor Associations 2026 1.0 null r3 part of medial pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20396 whole plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.516891 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.334356 inner portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.877238 GTEX-OXRN-0011-R5A-SM-2I5EF GTEx Tissue Sample Gene Expression Profiles 1.0 1.04235 BT-20 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.957685 cell junction GO Cellular Component Annotations 2015 1.0 null deutocerebrum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.221521 r1 part of vestibulocerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12457 KLF15_KO_GDS4780_419_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null periventricular stratum of r6Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.122 GSE213588_10_v_11_trametinib_human RummaGEO Drug Perturbation Signatures 1.0 null vesicle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 chemdependency GAD High Level Gene-Disease Associations 1.0 0.293278 cerebellar cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25782 SIRT3_KO_GDS4817_417_mouse_liver GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE198228,GSE198245_0_v_2_apoe_human RummaGEO Gene Perturbation Signatures -1.0 null Laterodorsal thalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.653 Prostate adenocarcinoma_PRAD_TCGA-CH-5740-01A-11R-1580-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4289 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.965816 nervous system disease GWASdb SNP-Disease Associations 1.0 0.081754 integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Sense organ TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 DHPS CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16718 cognitive disorder GWASdb SNP-Disease Associations 1.0 0.615118 Perturb_15069_KD_Twist1_SRP150075 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 PMC7438927-Table_2.XLSX-upregulated_in_AA-Unnamed_2_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WVLH-0011-R10A-SM-3MJFM GTEx Tissue Sample Gene Expression Profiles 1.0 1.11559 GTEX-UTHO-0011-R3A-SM-3GIK8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.09554 GSE195559_8_v_7_notch1_human RummaGEO Gene Perturbation Signatures 1.0 null GSE96641_1_v_4_esrp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null endopiriform nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.18986 ventrolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.825 EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BHMT CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.25205 GTEX-WVLH-0011-R5A-SM-3MJFW GTEx Tissue Sample Gene Expression Profiles 1.0 1.56049 PMC11908325-media-2.xlsx-Table10_MR-Unnamed_6_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null nrf1_22586274_liver_lof_mouse_gpl4134_gse35124 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.068628 H3K4me3_embryonic fibroblast_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null dorsal thalamus_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.63086 neuroendocrine cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.728975 hsa-miR-3117-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.880544 RPAP3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.67822 TBX2-33478486-IMR90-HUMAN-LUNG ChEA Transcription Factor Targets 2022 1.0 null acute leukemia GWASdb SNP-Phenotype Associations 1.0 0.349233 DBH_KO_GDS4324_362_mouse_Embryonic heart E10.5 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null HDAC6_KO_GSE27896_383_mouse_Foxp3+ T-regulatory cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null cerebellar cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.42429 H3K4me3_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-XOTO-0011-R9A-SM-4GICI GTEx Tissue Sample Gene Expression Profiles 1.0 0.8315 pineal gland Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.913955 coated vesicle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K4me3_H7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GTEX-PWO3-1026-SM-2I5F2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.929604 GTEX-TSE9-0011-R11A-SM-3DB7N GTEx Tissue Sample Gene Expression Profiles 1.0 1.09006 superficial stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01434 striatum_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.25517 KPL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.51729 transporter activity GO Molecular Function Annotations 2015 1.0 null GTEX-WHSE-0011-R3A-SM-3P5ZM GTEx Tissue Sample Gene Expression Profiles 1.0 0.902577 REST_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-X585-0011-R4B-SM-46MVH GTEx Tissue Sample Gene Expression Profiles 1.0 1.06667 SKCO1 CCLE Cell Line Gene Expression Profiles 1.0 1.55074 GTEX-X4XX-0011-R11A-SM-46MWQ GTEx Tissue Sample Gene Expression Profiles 1.0 1.27328 SU-DHL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.865538 mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.067633 Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A9PD-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LOXL2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.22939 GSE210101,GSE210114_1_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ET-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null MAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.801 Marvel domain InterPro Predicted Protein Domain Annotations 1.0 null GTEX-S7SE-0011-R8A-SM-2XCDG GTEx Tissue Sample Gene Expression Profiles 1.0 0.850782 stratum spinosum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.102704 GSE110268_1_v_3_foxd1_human RummaGEO Gene Perturbation Signatures -1.0 null GSE219195_0_v_5_rbm12_human RummaGEO Gene Perturbation Signatures -1.0 null HCC4006 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.824086 GSE210101,GSE210114_1_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null medial vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.893334 acute leukemia GWASdb SNP-Disease Associations 1.0 0.516361 GTEX-T6MN-0011-R4A-SM-32QPG GTEx Tissue Sample Gene Expression Profiles 1.0 1.00734 hsa-miR-3164 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 DIFI DepMap CRISPR Gene Dependency 1.0 6.9118 GTEX-RU72-0011-R7A-SM-2TF5U GTEx Tissue Sample Gene Expression Profiles 1.0 0.948143 GTEX-T6MN-0011-R5A-SM-32QPD GTEx Tissue Sample Gene Expression Profiles 1.0 1.84186 VZ in septal region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.17151 RAC3-21632823-H3396-HUMAN ChEA Transcription Factor Targets 2022 1.0 null FOXP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2102 Brain Lower Grade Glioma_LGG_TCGA-HT-7607-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null COV504 Achilles Cell Line Gene Essentiality Profiles 1.0 1.60835 OE19 CCLE Cell Line Gene CNV Profiles 1.0 1.50068 Brain Lower Grade Glioma_LGG_TCGA-HT-7856-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PSMD14 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.37615 organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 abnormality of divalent inorganic cation homeostasis GWASdb SNP-Phenotype Associations 1.0 0.377706 HCC1576 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.82108 ER-23166858-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null outer CP in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.900191 Superior olivary complex, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53773 Dendritic lamellar body COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.65 GBX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5872 medial part of r6B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23509 ZNF550 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.03128 tauopathy GWASdb SNP-Disease Associations 1.0 0.665868 principal pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05733 monogenic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.046512 stratum lucidum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.769855 Lake et al.Science.Ex8_Brain_Human CellMarker Gene-Cell Type Associations 1.0 null Outer plexiform layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.155 choroid plexus of the fourth ventricle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.07368 hippocampal pyramidal layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.740915 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039617 cerebellar cortex_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.27659 Motor neuron disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.09 POU5F1-16153702-HESC-human ChEA Transcription Factor Binding Site Profiles 1.0 null H3K27me3_keratinocyte_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null cell body COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.248216 Cytoplasmic vesicle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 hsa-miR-499-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 GSE213996_1_v_0_fhl3_mouse RummaGEO Gene Perturbation Signatures -1.0 null SMARCA4-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null olfactory bulb TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.576415 molecular_function GO Molecular Function Annotations 2015 1.0 null Olfactory lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.968 ZDHHC9 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.19195 Dendritic shaft COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.875 H3K27me3_H7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Distal dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.326 Fetal Growth Retardation CTD Gene-Disease Associations 1.0 1.20558 SJSA1 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.21797 hsa-miR-146b-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 plasma membrane LOCATE Curated Protein Localization Annotations 1.0 null Globus pallidus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.132 GSE73381,GSE73382_0_v_1_hira_mouse RummaGEO Gene Perturbation Signatures 1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null GTEX-QVUS-0011-R8A-SM-3GAD7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.978474 PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-SYMBOL_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-XOTO-2926-SM-4B65G GTEx Tissue Sample Gene Expression Profiles 1.0 0.931945 USF2 ENCODE Transcription Factor Targets 1.0 null GTEX-WWYW-0011-R7A-SM-3NB3H GTEx Tissue Sample Gene Expression Profiles 1.0 1.18624 periventricular stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.82054 BGC823 CCLE Cell Line Gene CNV Profiles -1.0 -1.84574 HT-115 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.29579 central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.050317 Communication disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.096 496100474_FWM_possible Alzheimer's disease_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.57347 clathrin-coated vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.887474 r3 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51266 Brain Lower Grade Glioma_LGG_TCGA-DU-7292-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Neurotransmitter receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.441 Agranular insular area, ventral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06371 GSE172020_0_v_2_testosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null CHAGO-K-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33455 GSE140997_4_v_5_nsun6_human RummaGEO Gene Perturbation Signatures 1.0 null establishment of localization GO Biological Process Annotations 2015 1.0 null Idiopathic downbeat nystagmus GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.504576 GSE149359_2_v_0_asap2_human RummaGEO Gene Perturbation Signatures 1.0 null Magnesium dbGAP Gene-Trait Associations 1.0 0.064687 PDCL3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.34546 H3K27me3_megakaryocyte_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null mantle zone of r5BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02591 HCC1171 CCLE Cell Line Gene Expression Profiles -1.0 -1.62693 hippocampus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.685143 Orbital area, medial part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.2724 Main olfactory bulb, outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.76035 GSE173262_2_v_5_ash1l_mouse RummaGEO Gene Perturbation Signatures 1.0 null mediodorsal nucleus of thalamus_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.942014 GSE140200_1_v_0_trim59_mouse RummaGEO Gene Perturbation Signatures 1.0 null bed nucleus of stria terminalis Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.899306 Tauopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.545 oocyte BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.825927 amygdaloid complex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.971373 Telencephalon TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 superficial stratum of r6Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41356 FOXO1::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.9255 PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR Rummagene Transcription Factor Associations 2026 1.0 null PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5 Rummagene Transcription Factor Associations 2026 1.0 null H3K4me1_heart_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null organelle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.318579 Pancreatic adenocarcinoma_PAAD_TCGA-H6-8124-11A-01R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JAK2_activemutant_178_GSE44961 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.82398 KP1NL Achilles Cell Line Gene Essentiality Profiles 1.0 1.21431 GTEX-T6MN-0011-R11A-SM-32QOX GTEx Tissue Sample Gene Expression Profiles 1.0 1.38941 PA-TU-8988T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.02988 CTCF ENCODE Transcription Factor Targets 1.0 null abnormality of lipid metabolism GWASdb SNP-Phenotype Associations 1.0 0.563675 SNU46 CCLE Cell Line Gene Expression Profiles -1.0 -2.33157 Cerebellar nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4213 p3x63ag8.653 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.753 GTEX-Q2AG-0011-R5A-SM-2HMJH GTEx Tissue Sample Gene Expression Profiles 1.0 1.55711 hippocampus BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.19253 C-fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.001 hsa-miR-4797-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 PMC11544636-CCS3-18-e12047-s001.xlsx-Supplementary_Table_S2-Supplementary_Table_S2_554_differentially_expressed_genes_between_DOX_and_CTR_D0_in_A673pTERshEWS_FLI1_model_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null Leading edge membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.749 Brain Lower Grade Glioma_LGG_TCGA-FG-7643-01A-11R-2090-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7IQ-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pontine raphe nucleus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.05242 GTEX-S7SE-2526-SM-2XCDL GTEx Tissue Sample Gene Expression Profiles 1.0 0.993653 GSE210101,GSE210114_6_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null cerebellar nuclei of CbV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07958 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.22209 HCC1143 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.899129 H3K27me3_kidney epithelial cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Intrinsic component of postsynaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.506 olfactory cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.746277 PFDN4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.03715 EZH2_HepG2_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null bladder GTEx Tissue Gene Expression Profiles -1.0 -1.08181 HOXB7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.27406 cognitive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.209583 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.58242 RPL37 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.36934 cerebellum_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.933833 GTEX-QVJO-0011-R2A-SM-2S1QK GTEx Tissue Sample Gene Expression Profiles 1.0 0.865456 TEAD4 ENCODE Transcription Factor Targets 1.0 null localization GO Biological Process Annotations 2015 1.0 null HOXB2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.0566 H3K4me1_cerebellum_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null MDAMB175VII Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.1743 COV413A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.840666 Brain Lower Grade Glioma_LGG_TCGA-HT-8107-01A-13R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null ZNF418 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.7126 Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCI-H1792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.71077 NCI-H2172 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.48112 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null Schizophrenia 2 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.024 pyramidal neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.740915 Perturb_9730_KD_SRP55_SRP106195 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 GSE202434,GSE202438_12_v_1_talazoparib_human RummaGEO Drug Perturbation Signatures -1.0 null NUGC-4 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.87491 JHH6 DepMap CRISPR Gene Dependency 1.0 2.62987 NCIH1694 CCLE Cell Line Gene CNV Profiles -1.0 -1.3967 hsa-miR-624 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.09784 Dorsal striatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.765 GTEX-WZTO-0011-R6B-SM-4E3J6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.63221 Skin Cutaneous Melanoma_SKCM_TCGA-RP-A690-06A-11R-A311-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_15747_KO_Cnga1_SRP327351 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -11.8714 GSE210101,GSE210114_4_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null NFATC4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7651 496100554_FWM_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.4036 cerebellar cortex_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.2966 GTEX-OHPN-0011-R7A-SM-2I5FI GTEx Tissue Sample Gene Expression Profiles 1.0 1.08671 Transport vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.039 GSE149035_7_v_0_hepacam_human RummaGEO Gene Perturbation Signatures 1.0 null BICR 31 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.04767 21NT DepMap CRISPR Gene Dependency 1.0 2.19887 cell projection COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Fog2_KO_GDS3659_152_mouse_adult heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-X261-0011-R5A-SM-3NMB4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.836585 abnormality of ion homeostasis GWASdb SNP-Phenotype Associations 1.0 0.180445 GTEX-XLM4-0011-R3B-SM-4AT6E GTEx Tissue Sample Gene Expression Profiles 1.0 1.0731 496100367_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.52454 H3K27me3_NT2-D1_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-T6MN-2526-SM-32PMN GTEx Tissue Sample Gene Expression Profiles 1.0 0.908073 NARS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.60528 SCC-25 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.899129 H2AFZ_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null bed nucleus of stria terminalis, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.36508 Dendritic branch COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.768 PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR Rummagene Transcription Factor Associations 2026 1.0 null Anterior olfactory nucleus, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15006 GTEX-NL4W-0011-R11A-SM-2I3DW GTEx Tissue Sample Gene Expression Profiles 1.0 1.13446 Brain Lower Grade Glioma_LGG_TCGA-DU-A7TG-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cul4A-RING E3 ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.555 cerebellar cortex_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.4395 GTF2F1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null striatum_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.5242 neoplasm by anatomical site GWASdb SNP-Phenotype Associations 1.0 0.107041 GRANTA-519 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13779 H3K4me2_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-TSE9-0011-R10A-SM-3DB7O GTEx Tissue Sample Gene Expression Profiles 1.0 0.94417 COLO818 CCLE Cell Line Gene CNV Profiles 1.0 1.41508 GSE119498_0_v_7_setd5_mouse RummaGEO Gene Perturbation Signatures 1.0 null bipolar affective disorder GWASdb SNP-Phenotype Associations 1.0 0.704969 UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.55613 Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FV-01A-11R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null dentate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.17052 H3K27me3_cardiac mesoderm_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null COLO800 CCLE Cell Line Gene CNV Profiles 1.0 1.97483 nucleus accumbens, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.94504 GTEX-N7MT-0011-R10A-SM-2I3E1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.16326 Alzheimer's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.532 HDAC2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC8709578-elife-69843-supp2.xlsx-MIX_E2_1h-Nearest_Ensembl_MIXL1 Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_cardiac mesoderm_hg19_6 ENCODE Transcription Factor Binding Site Profiles 1.0 null r6 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53527 MDAMB436 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.599732 PMC4860404-Table1.XLSX-MR_unique-Table_S1-7_DEG_unique_in_mouse_and_rat_SCI_at_1_dpi_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null r5 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03807 PMC11297310-41467_2024_50877_MOESM1_ESM.pdf-55-POU3F3_POU3F3 Rummagene Transcription Factor Associations 2026 1.0 null TF1 CCLE Cell Line Gene CNV Profiles -1.0 -1.60643 nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.04973 hsa-miR-181a TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 AGS Achilles Cell Line Gene Essentiality Profiles 1.0 1.02263 GSE145323,GSE145324_1_v_0_rfx3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Ribbon synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.937 Exocytic vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.534 PMC8387919-mmc2.xlsx-ST2_NEUROG3_binding_sites-Unnamed_12_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A857-01A-11R-A355-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-877-5p MiRTarBase microRNA Targets 1.0 null RND3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.021 GSE149264,GSE149267_4_v_5_trp53_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3118 DepMap CRISPR Gene Dependency 1.0 2.09216 DOK3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.56567 cytoplasmic part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.470005 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.998148 GSE101239_4_v_6_valproic acid_mouse RummaGEO Drug Perturbation Signatures 1.0 null coated vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 MCM6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17309 PMC12172627-NIHMS2085635-supplement-5.xlsx-E2F1_GENIE_Results-Unnamed_1_E2F1 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-25-3p MiRTarBase microRNA Targets 1.0 null A4/FUK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.33161 KYSE270 CCLE Cell Line Gene CNV Profiles -1.0 -2.09288 periventricular stratum of r7Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26463 intermediate stratum of LPrP Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03919 primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.5415 MAX_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Thalamus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.13068 GTEX-T2IS-0011-R6A-SM-32QP2 GTEx Tissue Sample Gene Expression Profiles 1.0 1.74281 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-11A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null synaptic vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K4me1_mammary epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null central nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null GSE120370_4_v_3_thrombin_mouse RummaGEO Drug Perturbation Signatures 1.0 null TFAP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.0113 abnormality of the endocrine system GWASdb SNP-Phenotype Associations 1.0 0.088879 GSE210101,GSE210114_5_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null SARS-CoV MA15_Day2-PFU-10^5_None_GSE50000 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 2.86765 GTEX-Q2AG-0011-R7A-SM-2HMJP GTEx Tissue Sample Gene Expression Profiles 1.0 0.986759 RORC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.8872 hsa-miR-3671 TargetScan Predicted Conserved microRNA Targets 1.0 0.474009 r6 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.122 GTEX-XMD1-2826-SM-4AT5F GTEx Tissue Sample Gene Expression Profiles 1.0 0.957104 PBX1 ChEA Transcription Factor Targets 1.0 null H3K27me3_Colonic Mucosa Roadmap Epigenomics Histone Modification Site Profiles 1.0 null lipid metabolism disorder GWASdb SNP-Disease Associations 1.0 0.660239 H3K4me1_placenta_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null SP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.887827 FOXJ2::ELF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.7425 GTEX-WL46-0011-R10A-SM-3MJFQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.986911 dorsal terminal nucleus of the accessory optic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10848 Somatosensory cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.191 NCI-H1573 COSMIC Cell Line Gene Mutation Profiles 1.0 null Main olfactory bulb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.80013 H3K27me3_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZFX_KO_GDS2718_150_mouse_embryonic stem cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Amyotrophic lateral sclerosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.119 PMC6590191__F3 PFOCR Pathway Figure Associations 2023 1.0 null PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-SYMBOL_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null HCC2935 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.25261 Uterine Carcinosarcoma_UCS_TCGA-N6-A4VD-01A-11R-A28V-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null encodes GeneRIF Biological Term Annotations 1.0 null Nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 ZNF528 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.1007 IRF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.1937 NCIH146 CCLE Cell Line Gene Expression Profiles 1.0 1.7947 Lung squamous cell carcinoma_LUSC_TCGA-37-4132-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ES-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RUNX1-27514584-CHIP-SEQ-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null EWS502 CCLE Cell Line Gene Expression Profiles 1.0 1.74093 P300-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE114685_1_v_0_grin2b_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-P44H-2426-SM-2XCEJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.02373 cell projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.459602 olfactorybulb BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 2.09859 GTEX-QVUS-0011-R6A-SM-3GACX GTEx Tissue Sample Gene Expression Profiles 1.0 1.30056 trigeminal BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 1.00325 GTEX-WVLH-2926-SM-3MJG5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.991291 GTEX-PVOW-0011-R3A-SM-32PKX GTEx Tissue Sample Gene Expression Profiles 1.0 1.33101 HIC1_01_205 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.00405 GSE211262,GSE211263_2_v_1_pbrm1_human RummaGEO Gene Perturbation Signatures -1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HV-A5A3-11A-11R-A26U-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE213588_8_v_5_trametinib_human RummaGEO Drug Perturbation Signatures 1.0 null Pyramidal neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.975 Neuron projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.154 coculture TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.236627 Forebrain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 NB6 DepMap CRISPR Gene Dependency 1.0 3.47827 protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040367 Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0EZ-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NR2F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 63.5278 Bhlha15 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.3019 GTEX-T5JC-0011-R11A-SM-32PMB GTEx Tissue Sample Gene Expression Profiles 1.0 1.23024 Prenatal Exposure Delayed Effects CTD Gene-Disease Associations 1.0 1.58771 GSE174522_1_v_0_spp1_mouse RummaGEO Gene Perturbation Signatures -1.0 null H3K27me3_Duodenum Smooth Muscle Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GTEX-X4XX-0011-R3B-SM-46MWK GTEx Tissue Sample Gene Expression Profiles 1.0 1.08417 intracellular organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.366623 artery disease GWASdb SNP-Disease Associations 1.0 0.18468 related GeneRIF Biological Term Annotations 1.0 null H3K27me3_K562_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null 697 DepMap CRISPR Gene Dependency 1.0 2.12177 Hindbrain TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.509 OLIG2-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null PMC7550584__F3 PFOCR Pathway Figure Associations 2024 1.0 null GSE124932_2_v_1_sarm1_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-WWYW-0011-R6A-SM-3NB3G GTEx Tissue Sample Gene Expression Profiles 1.0 1.76257 GTEX-QMR6-0011-R6A-SM-32PKP GTEx Tissue Sample Gene Expression Profiles 1.0 2.28986 primary motor-sensory cortex (samples)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.6927 GSE142684_3_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null BICR 10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.11214 FOXO4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2567 striatal neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.31332 nucleus lentiformis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.140378 GSE172020_0_v_3_testosterone_mouse RummaGEO Drug Perturbation Signatures -1.0 null Claustrum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.704 GTEX-QDT8-0011-R4A-SM-32PKM GTEx Tissue Sample Gene Expression Profiles 1.0 1.12173 GSE224294_4_v_2_ngly1_human RummaGEO Gene Perturbation Signatures -1.0 null ZBTB17 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.6443 OCUM1 CCLE Cell Line Gene Expression Profiles 1.0 2.7749 striatum_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.0458 membrane LOCATE Curated Protein Localization Annotations 1.0 null exocytic vesicle membrane GO Cellular Component Annotations 2025 1.0 null KDM5A_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Status epilepticus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.485 DMS273 CCLE Cell Line Gene Expression Profiles 1.0 1.4992 Cerebral lobe TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.976608 Periglomerular cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.408 cell culture TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.06552 Horizontal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.173 Neuron projection terminus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.094 H3K27me3_Penis Foreskin Fibroblast Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-625 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 GSE88819_3_v_12_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null primary motor cortex (area M1, area 4)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13385 H3K27me3_Brain Substantia Nigra Roadmap Epigenomics Histone Modification Site Profiles 1.0 null cancer GWASdb SNP-Disease Associations 1.0 0.104158 FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0001 Accessory olfactory bulb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.99714 outer CP in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.38076 PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaD_vs_NC-Gene_ERG Rummagene Transcription Factor Associations 2026 1.0 null GTEX-OHPN-0011-R1A-SM-2I5GB GTEx Tissue Sample Gene Expression Profiles 1.0 0.827914 retinal rod TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.633953 bed nucleus of the stria terminalis, laterocentral division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05798 GSE148252_1_v_4_npas4_mouse RummaGEO Gene Perturbation Signatures 1.0 null PSIP1_02_99 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 3.24793 MAEA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11991 GTEX-RNOR-2226-SM-2TF5O GTEx Tissue Sample Gene Expression Profiles 1.0 1.00163 medial subhabenular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3029 JUND_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1569 COSMIC Cell Line Gene Mutation Profiles 1.0 null HCC1599 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.57142 PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-SKOR2-gene_SKOR2 Rummagene Transcription Factor Associations 2026 1.0 null CHD7_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WHSE-2926-SM-3NMBG GTEx Tissue Sample Gene Expression Profiles 1.0 1.05614 diabetes mellitus GWASdb SNP-Disease Associations 1.0 0.48088 H3K27me3_BJ_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.858837 bounding membrane of organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.09819 MEF2B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.1236 GSE205976,GSE205978_1_v_0_cep83_human RummaGEO Gene Perturbation Signatures 1.0 null SP in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.833142 REST_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-NPJ7-0011-R8a-SM-2I3G2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.862094 Cerebral lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.219 OVMIU DepMap CRISPR Gene Dependency 1.0 9.4465 superficial stratum of r5BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51188 H3K27me3_SK-N-SH_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null cellular_component LOCATE Curated Protein Localization Annotations 1.0 null PMC7064149-CAM4-9-2062-s004.xlsx-Table_S5-Table_S5_DEGs_between_low-_and_high-FOXP4-AS1_expression_groups_in_PDAC_tumor_tissues_FOXP4 Rummagene Transcription Factor Associations 2026 1.0 null Limbic system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.764 striatum_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.49834 Postsynaptic density COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.563 PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-orthofinder_human_gene_names_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null HNF4, COUP MotifMap Predicted Transcription Factor Targets 1.0 null BE2M17 DepMap CRISPR Gene Dependency 1.0 2.36967 GTEX-RU72-0011-R11A-SM-2TF6J GTEx Tissue Sample Gene Expression Profiles 1.0 1.22351 GTEX-QVJO-0011-R8A-SM-447C7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.94096 occipital neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.41931 GTEX-X4XX-0011-R6B-SM-46MWP GTEx Tissue Sample Gene Expression Profiles 1.0 1.69896 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null MHH-ES-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.43575 H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HBL-100 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.76003 superficial stratum of r3BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20342 H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3HZ-01A-11R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null DTX3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.13266 H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null GTEX-RVPU-0011-R5A-SM-2XCAD GTEx Tissue Sample Gene Expression Profiles 1.0 1.38082 lateral (dentate) cerebellar nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19528 thoracic cancer GWASdb SNP-Disease Associations 1.0 0.757039 NCIH1092 CCLE Cell Line Gene Expression Profiles 1.0 1.40971 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7051-11A-02R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Memory Disorders CTD Gene-Disease Associations 1.0 1.10838 GLC82 CCLE Cell Line Gene CNV Profiles -1.0 -1.49938 autosomal dominant disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.056903 abnormality of magnesium homeostasis GWASdb SNP-Phenotype Associations 1.0 0.582458 Flocculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11379 hsa-miR-4665-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GSE88819_3_v_8_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null cerebellar cortex_17 pcw_F_12880 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.955409 GTEX-PWO3-0011-R5A-SM-2I5EZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.05852 PMC9882185-media-4.xlsx-Neuron_KD-gene_name_AR Rummagene Transcription Factor Associations 2026 1.0 null H3K27me3_cardiac mesoderm_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null ZNF211 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.5869 vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.812111 PLB985 Achilles Cell Line Gene Essentiality Profiles 1.0 1.29135 GATA3_SH-SY5Y_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HCC1806 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.21432 hsa-miR-582-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 PMC8423434-mmc7.xlsx-OCT4_Primed-Genes_n_912_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null r4 part of cochlear sensory column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28013 chr3_63302578_A_C_b38 GTEx eQTL 2025 1.0 1.00898 IM95 CCLE Cell Line Gene CNV Profiles -1.0 -2.00106 hippocampus TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null cytoplasmic vesicle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.751357 MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 2.01203 Olfactory tubercle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.827 H3K27me3_cardiac mesoderm_hg19_5 ENCODE Transcription Factor Binding Site Profiles 1.0 null tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null intermediate part of r6B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.89178 primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.37058 SCLC21H CCLE Cell Line Gene Expression Profiles 1.0 1.52397 GSE138938_1_v_2_foxp2_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-NPJ8-0011-R6a-SM-2HMKB GTEx Tissue Sample Gene Expression Profiles 1.0 1.77384 GTEX-NL3H-0011-R3a-SM-2I3GL GTEx Tissue Sample Gene Expression Profiles 1.0 1.15579 high vocal center TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.774004 Ependymocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.075 Congenital left-sided heart lesions GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.652288 tail of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02873 deep layers of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.916256 Perturb_3445_OE_Sca17_SRP248035 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 3.06372 disease of cellular proliferation GWASdb SNP-Disease Associations 1.0 0.10171 occipital neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.20626 GTEX-N7MS-0011-R2a-SM-2HML6 GTEx Tissue Sample Gene Expression Profiles 1.0 0.839095 TNFRSF11A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.3007 Cerebral cortex TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 claustrum, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.29685 CORL279 CCLE Cell Line Gene Expression Profiles 1.0 2.78381 synaptic vesicle membrane GO Cellular Component Annotations 2023 1.0 null Interneuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.967 GSE223008_6_v_8_calhm6_mouse RummaGEO Gene Perturbation Signatures 1.0 null ARNT_01_240 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.11257 homologue GeneRIF Biological Term Annotations 1.0 null GTEX-T6MN-0011-R6A-SM-32QP8 GTEx Tissue Sample Gene Expression Profiles 1.0 2.09765 EP300_osteoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null urinary system disease GWASdb SNP-Disease Associations 1.0 0.246885 abnormality of the cardiovascular system GWASdb SNP-Phenotype Associations 1.0 0.041556 Perturb_8514_KO_Setd1b_SRP328849 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -8.30009 GTEX-S7SE-0011-R6A-SM-2XCD9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.56023 eye TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null neuronal cell body COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.277774 Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6132-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SZ in midcingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.965469 abnormality of higher mental function GWASdb SNP-Phenotype Associations 1.0 0.245175 ALG2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.42846 Synaptic vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 Entorhinal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.619 GSE138938_1_v_3_foxp2_human RummaGEO Gene Perturbation Signatures 1.0 null HCC1806 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.38486 GSE145323,GSE145324_3_v_2_rfx3_mouse RummaGEO Gene Perturbation Signatures -1.0 null GTEX-P44H-0011-R10A-SM-2XCEK GTEx Tissue Sample Gene Expression Profiles 1.0 0.994145 PE01 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.919568 GSE149264,GSE149267_9_v_3_trp53_mouse RummaGEO Gene Perturbation Signatures 1.0 null intracellular organelle part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 PMC12354852-41467_2025_62818_MOESM3_ESM.xlsx-Sup_Data_10-Differentially_expressed_genes_in_TAF6L_KD_vs_Control_AR Rummagene Transcription Factor Associations 2026 1.0 null mRNA_RXRA_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_associated_gene_name_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null LNCAP-CLONE-FGC COSMIC Cell Line Gene Mutation Profiles 1.0 null H3K4me1_olfactory bulb_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null abnormality of the breast GWASdb SNP-Phenotype Associations 1.0 0.655429 Prostate adenocarcinoma_PRAD_TCGA-HC-A632-01A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-X4XX-2926-SM-3NMB1 GTEx Tissue Sample Gene Expression Profiles 1.0 1.08538 PPARD ChEA Transcription Factor Targets 1.0 null GTEX-WZTO-0011-R7B-SM-4E3IS GTEx Tissue Sample Gene Expression Profiles 1.0 1.14652 H3K4me3_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null amygdaloid complex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.14107 NCI-H1435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.824086 Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7044-11A-01R-1965-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NPJ7-0011-R1a-SM-3GACT GTEx Tissue Sample Gene Expression Profiles 1.0 1.06189 AOB, mitral cell layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.1089 RAD21 ENCODE Transcription Factor Targets 1.0 null central nervous system disease GWASdb SNP-Disease Associations 1.0 0.099813 PMC8423434-mmc7.xlsx-SOX2_HENSM-Genes_n_2733_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null USF2_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE250534_4_v_1_cabergoline_mouse RummaGEO Drug Perturbation Signatures 1.0 null Pinealocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.84 OB outer plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.72499 Congenital heart disease (inherited effect) GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.539794 Dentate gyrus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39358 cerebellar cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.03461 IGROV-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null tail of caudate Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.89198 GATA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.9397 cytoplasmic part LOCATE Curated Protein Localization Annotations 1.0 null GTEX-NPJ8-0011-R5a-SM-2HMJY GTEx Tissue Sample Gene Expression Profiles 1.0 0.979932 nucleus subceruleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.885667 cell part LOCATE Curated Protein Localization Annotations 1.0 null KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.936276 GTEX-X4XX-0011-R10B-SM-46MWO GTEx Tissue Sample Gene Expression Profiles 1.0 1.0217 PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null snoutepidermis BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.866115 sense organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.482428 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 periventricular stratum of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.94511 parietal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.98598 inferior olivary complex, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.63732 GTEX-TSE9-0011-R5A-SM-3DB7J GTEx Tissue Sample Gene Expression Profiles 1.0 1.34376 Habenula TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.079 EZH2 ENCODE Transcription Factor Targets 1.0 null heart GTEx Tissue Gene Expression Profiles 1.0 0.942348 H3K27me3_CD8 Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Granular insular cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.666 H3K4me3_cortical plate_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null LN215 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.01306 TFAP4::FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.919 CHD1_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null IRF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.6844 PMC11908325-media-2.xlsx-Table10_MR-Unnamed_7_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null Pparg::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 35.0752 Exocytic vesicle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 GSE181959_1_v_2_dextran_mouse RummaGEO Drug Perturbation Signatures 1.0 null PMC8423434-mmc7.xlsx-OCT4_HENSM-Genes_n_666_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null H4K20me1_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Hippocampal mossy fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.331 striatum_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.963869 inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.887156 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_DLX3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null G protein-coupled receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.893 Syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.118 neuron projection terminus COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.387365 hsa-miR-4282 TargetScan Predicted Conserved microRNA Targets 1.0 0.159923 CDX2-22108803-LS180-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE100464,GSE100465_0_v_3_atrx_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-RVPV-0011-R5A-SM-2TF69 GTEx Tissue Sample Gene Expression Profiles 1.0 1.24464 superficial layers of caudal presubiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.851784 EP300-20729851-FORBRAIN_MIDBRAIN_LIMB_HEART-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null Tcof1_OE_GDS998_154_mouse_neuroblastoma N1E-115 cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null hsa-miR-516b TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51F-06A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pituitary GTEx Tissue Gene Expression Profiles 1.0 1.1597 primary motor-sensory cortex (samples)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.38504 496100409_FWM_no dementia_TBI_85_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.23556 abnormality of the urinary system GWASdb SNP-Phenotype Associations 1.0 1.05869 leukemia GWASdb SNP-Disease Associations 1.0 0.328173 bounding membrane of organelle GO Cellular Component Annotations 2015 1.0 null TEAD1 JASPAR Predicted Transcription Factor Targets 1.0 null Skeletal Muscle Female Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles 1.0 1.67869 disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.048719 GTEX-Q2AG-0011-R4A-SM-2HMKA GTEx Tissue Sample Gene Expression Profiles 1.0 0.981104 GSE216147_2_v_3_rbm20_mouse RummaGEO Gene Perturbation Signatures 1.0 null GTEX-QVUS-0011-R4A-SM-3GAE7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.9487 ERF::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9016 GTEX-RVPU-0011-R10A-SM-2XCAH GTEx Tissue Sample Gene Expression Profiles 1.0 0.924464 ppard_23093780_pancreatic_beta_cells_lof_mouse_gpl1261_gds4320 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.165846 abnormality of nervous system morphology GWASdb SNP-Phenotype Associations 1.0 0.072431 hsa-miR-3158-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-01A-11R-A18T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CIART CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4349 GSE144231_4_v_7_cxcr2_mouse RummaGEO Gene Perturbation Signatures -1.0 null sensory system disease GWASdb SNP-Disease Associations 1.0 0.503485 hsa-miR-4418 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 rhombomere 6 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01777 Dentate gyrus, polymorph layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.48492 hsa-miR-335-5p MiRTarBase microRNA Targets 1.0 null Lateral entorhinal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.968 Focal epilepsy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.975 gigantocellular group, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.959783 Perturb_12854_KD_Pdx1_SRP149543 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 20.0 GTEX-UTHO-0011-R6A-SM-3GIJW GTEx Tissue Sample Gene Expression Profiles 1.0 1.97221 GSE124471,GSE124488_1_v_0_lats1_mouse RummaGEO Gene Perturbation Signatures 1.0 null external granular (germinal) layer of upper rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.76632 Limbic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.194 ventral claustrum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10938 body of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.10907 PAX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 63.3038 PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-hsapiens_homolog_ensembl_gene_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Gene_Name_MIXL1 Rummagene Transcription Factor Associations 2026 1.0 null JAK2_knockout_79_GSE26188 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.6097 Granule cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.145 Oliva TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.718 496100405_TCx_probable Alzheimer's disease_no TBI_88_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.5228 GTEX-N7MT-1226-SM-2D7W4 GTEx Tissue Sample Gene Expression Profiles 1.0 0.984238 ERF::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 35.7455 HCC461 DepMap CRISPR Gene Dependency 1.0 2.23126 PMC5131312-srep38063-s2.xls-ST12-Unnamed_6_KLF6 Rummagene Transcription Factor Associations 2026 1.0 null Brain Lower Grade Glioma_LGG_TCGA-FG-A4MT-02A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PrefrontalCortex BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.995873 STAP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10908 synaptic vesicle membrane GO Cellular Component Annotations 2025 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-A83J-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4489 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 Medial septum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.583 hsa-miR-591 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.7397 TP53 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.3738 496100596_FWM_dementia_TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.22784 globose nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.855657 GTEX-P44H-0011-R1A-SM-3NM8J GTEx Tissue Sample Gene Expression Profiles 1.0 0.880335 496100484_FWM_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.79503 tissues, cell types and enzyme sources TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 GTEX-R55E-0011-R11A-SM-2TC6I GTEx Tissue Sample Gene Expression Profiles 1.0 1.35887 NCI-H2369 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.824086 ventrolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.989808 TCF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0819 GTEX-X4XX-0011-R4B-SM-46MWL GTEx Tissue Sample Gene Expression Profiles 1.0 1.10261 hsa-miR-4424 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 EVPL CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.226 other source TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.064362 HNRNPU CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16992 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.950072 endocrine gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053876 Primary hematopoietic stem cells G-CSF-mobilized Male Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles -1.0 -0.957893 SOX2-21211035-LN229-GBM ChEA Transcription Factor Targets 2022 1.0 null abnormality of cation homeostasis GWASdb SNP-Phenotype Associations 1.0 0.180445 GTEX-QDT8-3026-SM-32PKB GTEx Tissue Sample Gene Expression Profiles 1.0 0.934886 GTEX-WL46-2826-SM-3LK81 GTEx Tissue Sample Gene Expression Profiles 1.0 1.18807 MDA-MB-435 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.854592 Nr1h3::Rxra JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.2112 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.1555 synapse COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 synapse part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.18132 Axon collateral COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.044 AOB, internal plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.4474 PPARD-21283829-MYOFIBROBLAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null PMC8528285-pbio.3001085.s010.xlsx-Fig_S8C-GENE_LIST_UPLOADED_TO_ENRICHR_MAX_KO_3T3_DE_NOVO_69_GENES_MAX Rummagene Transcription Factor Associations 2026 1.0 null cerebellar cortex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.865988 CSTB_KO_GSE47516_678_mouse_mouse cerebellum at P30 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-N7MS-0011-R6a-SM-2HMJ4 GTEx Tissue Sample Gene Expression Profiles 1.0 1.94995 UACC-257 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.76359 GTEX-XLM4-0011-R4B-SM-4AT5C GTEx Tissue Sample Gene Expression Profiles 1.0 1.04089 LCK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39241 SK-MEL-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.45926 PANC 03.27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14724 Perturb_4492_KO_Tcf4_SRP072458 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -20.0 Dendritic spine COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.695 r6 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06718 SLR21 CCLE Cell Line Gene Expression Profiles -1.0 -2.12541 GTEX-OHPN-0011-R11A-SM-2I5FM GTEx Tissue Sample Gene Expression Profiles 1.0 1.02337 Neuron spine COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.695 Perturb_8779_Mut_SMARCB1_SRP223162 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 atherosclerosis GWASdb SNP-Phenotype Associations 1.0 0.262174 GTEX-XLM4-0011-R10A-SM-4AT5P GTEx Tissue Sample Gene Expression Profiles 1.0 1.01202 IRAK2_knockout_39_GSE10765 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.46183 superficial stratum of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62689 dorsalstriatum BioGPS Mouse Cell Type and Tissue Gene Expression Profiles 1.0 0.912704 Agranular insular area, dorsal part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22752 GSE180185_4_v_1_setbp1_human RummaGEO Gene Perturbation Signatures -1.0 null primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.15924 MCF-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.74423 Brodmann area 36 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.772 Cognition Disorders CTD Gene-Disease Associations 1.0 1.12703 heart BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -1.00717 mania GWASdb SNP-Phenotype Associations 1.0 0.704969 GTEX-QVJO-0011-R9A-SM-2S1QH GTEx Tissue Sample Gene Expression Profiles 1.0 1.06722 corpus callosum Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.75303 High vocal center TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.586 GTEX-R55E-2526-SM-2TC6H GTEx Tissue Sample Gene Expression Profiles 1.0 0.966177 Main olfactory bulb, inner plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.76703 Brain Lower Grade Glioma_LGG_TCGA-FG-8181-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-4263 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.843347 GSE218580_1_v_5_fentanyl_mouse RummaGEO Drug Perturbation Signatures 1.0 null MEF2A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.2989 496100278_FWM_no dementia_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -3.06043 Neuron to neuron synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.632 NRL_Deficiency_GDS1693_238_mouse_Photoreceptors cells of retinas at P10 GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null chr3_63310085_A_T_b38 GTEx eQTL 2025 1.0 1.76616 GTEX-X585-3026-SM-46MWF GTEx Tissue Sample Gene Expression Profiles 1.0 0.872764 neuropil TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.22246 cerebellar cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.865988 Anthranilate synthase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.573 MPV17L2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01604 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 H3K4me3_BE2C_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null GSE242199_6_v_3_ntrk2_human RummaGEO Gene Perturbation Signatures 1.0 null K562 Achilles Cell Line Gene Essentiality Profiles 1.0 1.20517 H3K27me3_CD4+ CD25- CD45RA+ Naive Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE200388_0_v_1_gemin5_human RummaGEO Gene Perturbation Signatures 1.0 null respiratory epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.101288 layer V of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.46045 AOB, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.06048 superficial stratum of r3BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12408 PKCTHETA-26484144-CHIP-SEQ-BREAST-HUMAN ChEA Transcription Factor Targets 2022 1.0 null bronchial disease GWASdb SNP-Disease Associations 1.0 0.937304 GTEX-R55E-0011-R6A-SM-2TC5T GTEx Tissue Sample Gene Expression Profiles 1.0 1.49687 Eye-retinal bipolar neuron Tabula Sapiens Gene-Cell Associations 1.0 1.12522 USF2 JASPAR Predicted Transcription Factor Targets 1.0 null GSK3_INHIBITION_GDS4043_459_human_MLL leukemia cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null organelle part GO Cellular Component Annotations 2015 1.0 null membrane GO Cellular Component Annotations 2015 1.0 null Perturb_15070_KD_Twist1_SRP150075 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 10.0076 NCIH2452 Achilles Cell Line Gene Essentiality Profiles 1.0 1.63126 GTEX-XMD1-0011-R6A-SM-4AT5K GTEx Tissue Sample Gene Expression Profiles 1.0 1.62952 layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.89507 NCI-H1793 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.920409 SNU520 CCLE Cell Line Gene CNV Profiles 1.0 2.09605 organism form TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.474258 GTEX-X585-0011-R10A-SM-46MUY GTEx Tissue Sample Gene Expression Profiles 1.0 1.15911 Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null hsa-miR-448 TargetScan Predicted Conserved microRNA Targets 1.0 0.541706 Perturb_9446_KO_STK25_SRP356933 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 11.6062 H3K27me3_GM12878_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null Ovary BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.40184 hsa-miR-4328 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.20993 TC32 CCLE Cell Line Gene Expression Profiles 1.0 2.48813 DBP JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.3731 inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.988537 PMC11266694-41698_2024_651_MOESM1_ESM.pdf-2-ZNF469_ZNF469 Rummagene Transcription Factor Associations 2026 1.0 null GSE112761,GSE112767_2_v_0_ddx6_mouse RummaGEO Gene Perturbation Signatures -1.0 null GATA3_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CDX2 ChEA Transcription Factor Targets 1.0 null Bam protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.728 Ventricular zone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.027 cell junction COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 cerebellar cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.19698 Proximal dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.417 mRNA_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null cerebral cortex HPA Tissue Protein Expression Profiles 1.0 2.04572 TCF4-23295773-U87-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-NEUN_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6 Rummagene Transcription Factor Associations 2026 1.0 null keratinocyte cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.22246 choroid plexus of the lateral ventricle Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.74122 striatum_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.25782 TRIM28 ChEA Transcription Factor Targets 1.0 null MSRB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.39909 Head TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 VZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.861909 PHF8 ENCODE Transcription Factor Targets 1.0 null MDAMB468 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.816867 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.13779 SAP30_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null vascular disease GWASdb SNP-Disease Associations 1.0 0.139165 parietal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.07184 OB olfactory fiber layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.56921 primary motor cortex (area M1, area 4)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.16411 Synucleinopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.25 GTEX-WL46-0011-R7A-SM-3LK7X GTEx Tissue Sample Gene Expression Profiles 1.0 1.17131 cerebral hemisphere TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Bipolar disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.213 hsa-miR-1283 TargetScan Predicted Conserved microRNA Targets 1.0 0.419947 Distal axon COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.002 r6 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.42716 Nucleus y Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.19637 ZNF354A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 88.0222 GTEX-N7MS-0011-R5a-SM-2HMK8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.34732 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.26473 CD34+ BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.905728 Brain TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-EGR1_DC_ChIP-seq_EGR1 Rummagene Transcription Factor Associations 2026 1.0 null hsa-miR-877-3p MiRTarBase microRNA Targets 1.0 null orbital frontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.944039 H3K4me3_cardiac mesoderm_hg19_5 ENCODE Histone Modification Site Profiles 1.0 null ZNF474 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.23856 BCL6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.7475 Glutamatergic synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.475 GTEX-WVLH-0011-R11A-SM-3MJFO GTEx Tissue Sample Gene Expression Profiles 1.0 1.30612 intrinsic component of organelle membrane GO Cellular Component Annotations 2015 1.0 null GTEX-XOTO-0011-R7B-SM-4B64R GTEx Tissue Sample Gene Expression Profiles 1.0 0.831955 Ventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1548 Temporal lobe TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 IFT172 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.41995 GSE197850_4_v_3_glucagon_human RummaGEO Drug Perturbation Signatures 1.0 null mantle zone of OB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.77255 posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00694 PMC8816717-mmc2.xlsx-TgCRND8_P113-Unnamed_2_STAT2 Rummagene Transcription Factor Associations 2026 1.0 null GATA3-24758297-MCF-7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null occipital neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.25257 PMC12616242-can-24-3452_supplementary_table_s4_suppst4.xlsx-EWSR1FLI-KDM6A_genes-Genes_associated_to_EWSR1_FLI1-KDM6A_peaks_in_A-673_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null levetiracetam_rattus norvegicus_gpl1355_frontal cortex_gds1864 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null cytoplasmic membrane-bounded vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.4667 GSE96641_5_v_2_esrp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null r2 part of anteroventral cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47825 Scoliosis, Isolated, Susceptibility To, 3 DisGeNET Gene-Disease Associations 1.0 null ELK1 JASPAR Predicted Transcription Factor Targets 1.0 null GSE180185_4_v_10_setbp1_human RummaGEO Gene Perturbation Signatures -1.0 null PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-8113-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE164757,GSE164759_4_v_3_trametinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null EFO21 CCLE Cell Line Gene CNV Profiles -1.0 -1.60626 dementia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.282582 SCC25 CCLE Cell Line Gene Expression Profiles -1.0 -1.8018 dexamethasone_homo sapiens_gpl4133_gse42619 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Hippocampal pyramidal layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.975 GSE146687_2_v_5_eribulin_human RummaGEO Drug Perturbation Signatures -1.0 null TCF4 ChEA Transcription Factor Targets 1.0 null Perturb_6393_KO_Ngr1_SRP098816 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.77091 GSE205163,GSE205164_2_v_4_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null RT-112 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2534 hematologic cancer GWASdb SNP-Disease Associations 1.0 0.165703 immune system cancer GWASdb SNP-Disease Associations 1.0 0.165703 KLF15_KO_GDS4780_509_mouse_heart GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null ZNF140 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 39.9891 laterodorsal part of putamen Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.16676 cerebellar cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.587228 Nucleus of the optic tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06693 GTEX-QDT8-0011-R11A-SM-32PKD GTEx Tissue Sample Gene Expression Profiles 1.0 1.18095 Dyslexia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.174 Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23785 GTEX-S7SE-0011-R7A-SM-2XCDI GTEx Tissue Sample Gene Expression Profiles 1.0 1.50463 HOXA7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.3233 Cochlear nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.3645 GTEX-T6MN-0011-R10A-SM-32QP7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05535 Heart BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.43271 GTEX-QDT8-0011-R10A-SM-32PKG GTEx Tissue Sample Gene Expression Profiles 1.0 1.07824 STAT1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.9994 Perturb_8637_KO_Arid1a_SRP312002 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -11.8265 Neuron projection membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.787 GTF2F1 ENCODE Transcription Factor Targets 1.0 null cell projection part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.207794 GTEX-NPJ7-2826-SM-2I3FU GTEx Tissue Sample Gene Expression Profiles 1.0 0.910365 PHF8_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null G protein-coupled GABA receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.109 intermediate stratum of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4676 PPARD_KO_GSE16048_54_mouse_pancreas (islets, PDX1-expressing cells) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null intracellular organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.047842 Octamer MotifMap Predicted Transcription Factor Targets 1.0 null Periplasmic side of cell outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.728 lateral portion of the shell Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.11346 GSE183994_1_v_0_scml2_mouse RummaGEO Gene Perturbation Signatures -1.0 null globus pallidus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.239307 NCIH1993 DepMap CRISPR Gene Dependency 1.0 3.60058 Flocculus, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10214 COLO741 CCLE Cell Line Gene CNV Profiles 1.0 1.70893 Integral component of postsynaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.537 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.17747 cerebellar cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.7187 GTEX-X585-0011-R11B-SM-46MUZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.15847 Endoplasmic reticulum cisternal network COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.501 Axolemma COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.804 MITF ChEA Transcription Factor Targets 1.0 null GTEX-XMD1-0011-R11A-SM-4AT5J GTEx Tissue Sample Gene Expression Profiles 1.0 1.14819 POU3F1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.19273 GTEX-PVOW-2526-SM-2XCF7 GTEx Tissue Sample Gene Expression Profiles 1.0 0.908814 H3K4me2_astrocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Bed nuclei of the stria terminalis, posterior division, strial extension Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0789 primary motor cortex (area M1, area 4)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.844871 UACC62 CCLE Cell Line Gene CNV Profiles 1.0 1.35684 Oct-1 MotifMap Predicted Transcription Factor Targets 1.0 null Perturb_938_KO_Gcgr_SRP238015 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.4239 Mullerian aplasia and hyperandrogenism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.012 PMC6938365-pone.0226733.s018.txt--NANOG_NANOG Rummagene Transcription Factor Associations 2026 1.0 null abnormality of the immune system GWASdb SNP-Phenotype Associations 1.0 0.14119 primary motor cortex (area M1, area 4)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09577 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YY-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE157555,GSE157556_0_v_6_foxa2_mouse RummaGEO Gene Perturbation Signatures 1.0 null anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.20626 PMC8387919-mmc2.xlsx-ST8_NEUROG3_and_islets_expr-Supplemental_Table_8_NEUROG3_bound_genes_and_expression_in_islet_lineage_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null superficial stratum of r2BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08794 mediodorsal nucleus of thalamus_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.915352 psychosis GWASdb SNP-Phenotype Associations 1.0 0.590538 sense organ TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Retinal stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.942 principal sensory nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.849819 dorsolateral prefrontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.63718 GTEX-RU72-0011-R5A-SM-2TF6U GTEx Tissue Sample Gene Expression Profiles 1.0 1.55728 Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3EV-06A-11R-A20F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null OCT4-20526341-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Excretory gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.946 Cul4-RING E3 ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.551 liminal part of the r6 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32432 GSE219195_4_v_5_rbm12_human RummaGEO Gene Perturbation Signatures -1.0 null tail of caudate nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.18234 intermediate stratum of r6BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23509 CDC123 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.77097 nose TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.174799 Lung adenocarcinoma_LUAD_TCGA-91-6847-01A-11R-1949-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EP300_SK-N-SH_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null cerebellar cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.36659 NCIH1792 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.87515 disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039945 GTEX-T2IS-0011-R3A-SM-32QPB GTEx Tissue Sample Gene Expression Profiles 1.0 1.17308 PMC4149371-pone.0105180.s010.xls-OCT4-GENE_POU5F1 Rummagene Transcription Factor Associations 2026 1.0 null r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00908 olfactory tubercle Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.01061 H3K27me3_megakaryocyte_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null REDD1_Repression_GDS3558_73_human_Blood Myeloid Cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null GSE100528_1_v_0_mettl3_mouse RummaGEO Gene Perturbation Signatures -1.0 null Anterior olfactory nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46783 Mesothelioma_MESO_TCGA-LK-A4NY-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null abnormality of cellular immune system GWASdb SNP-Phenotype Associations 1.0 0.081111 Schizophrenia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.622 Telencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.213 NCI-H209 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33455 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.964375 PHF20 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.75564 lateral hemisphere of cerebellum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03554 Medial habenula Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.67342 Brain Lower Grade Glioma_LGG_TCGA-DU-8162-01A-21R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14686_KO_Sirt3_SRP277814 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 18.2518 SNU1105 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.25814 corpus striatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.141965 olfactory lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.574416 synaptic vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 1.40466 Retinal rod TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.695 PU.1 MotifMap Predicted Transcription Factor Targets 1.0 null 19185848-TableS1 GeneSigDB Published Gene Signatures 1.0 null COLO 800 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.83229 morphological abnormality of the central nervous system GWASdb SNP-Phenotype Associations 1.0 0.081604 hsa-miR-19a TargetScan Predicted Conserved microRNA Targets 1.0 0.127531 SP3_Deficiency_GDS3058_610_mouse_Embryonic heart (day 12.5 C57Bl/6) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null POLR2A_cortical plate_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE88819_5_v_9_tug1_mouse RummaGEO Gene Perturbation Signatures 1.0 null lung TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057791 Perturb_5663_KD_HOXD13_SRP256218 PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 20.0 nervous system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null H4K20me1_HepG2_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null striatum_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.27659 pineal gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.220831 FOXO1::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4324 Autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.052 olivary pretectal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00579 Mesopallium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.788 hsa-miR-181c TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 hsa-miR-582-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 perikaryon COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.336619 GTEX-OXRN-0011-R10A-SM-2I5GC GTEx Tissue Sample Gene Expression Profiles 1.0 0.896834 Stratum lucidum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.408 olfactory bulb, principal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.77255 biological_process GO Biological Process Annotations 2015 1.0 null H3K4me1_H1 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null hsa-miR-518a-5p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 PPP1CA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12161 SZ in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.875482 FOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8648 Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Anterior olfactory nucleus, external part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.89343 Metencephalon TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.509 PC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26689 inner SZ in midlateral extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.980481 obesity GWASdb SNP-Disease Associations 1.0 0.660239 protein binding GO Molecular Function Annotations 2015 1.0 null PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-SYMBOL_DBP Rummagene Transcription Factor Associations 2026 1.0 null NCIH1650 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.40528 ERF::FOXO1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.7907 Malignant Neoplasm DisGeNET Gene-Disease Associations 1.0 null GTEX-RNOR-0011-R7A-SM-2TF4V GTEx Tissue Sample Gene Expression Profiles 1.0 1.28776 hsa-miR-527 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 amygdalostriatal transition area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.23648 neuroblast TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.255234 lower limb region of M1 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.37222 LMX1A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8677 GTEX-QDT8-0011-R7A-SM-32PKF GTEx Tissue Sample Gene Expression Profiles 1.0 2.09401 Intrinsic component of periplasmic side of cell outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.728 CST3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.44719 inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.5338 striatum_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.865988 Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FO-11A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE117730,GSE117732_0_v_2_apobec2_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4 Rummagene Transcription Factor Associations 2026 1.0 null limbic system TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null adult TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.561644 Facial motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.28919 hsa-miR-4279 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.13535 anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.26592 NCIH838 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.17543 GSE223008_4_v_12_calhm6_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC7415402-oncotarget-11-2995-s004.xlsx-EWS-FLI1_Type_1_vs_Type_2-Gene_Symbol_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null cell COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.334356 whole body TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 neuron projection GO Cellular Component Annotations 2015 1.0 null r7 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40645 dorsal part of alar p2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37174 layer 2 of LOT Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31526 MDAMB157 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.769868 Ionotropic glutamate receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.298 Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A20R-01A-12R-A16R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-QMR6-1326-SM-32PLB GTEx Tissue Sample Gene Expression Profiles 1.0 0.999025 Language disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.195 KPNYS DepMap CRISPR Gene Dependency 1.0 3.50011 clathrin-coated vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70X-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Spinocerebellar ataxia type 27 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.123 GTEX-NPJ8-0011-R10A-SM-2YUMO GTEx Tissue Sample Gene Expression Profiles 1.0 0.967827 UACC-62 COSMIC Cell Line Gene Mutation Profiles 1.0 null PMC12619835-41467_2025_66007_MOESM12_ESM.xlsx-KLF5_activated_H3K27ac_AsPC1-Nearest_Gene_Name_KLF5 Rummagene Transcription Factor Associations 2026 1.0 null superficial stratum of r5BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.20342 OB glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.65877 PMC6938365-pone.0226733.s020.txt--CTCF_CTCF Rummagene Transcription Factor Associations 2026 1.0 null Perineuronal net TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.752 H3K27me3_astrocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null amacrine cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.703127 posteroventral (inferior) parietal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.882879 Mouse - Motor Cortex - Cluster - Sst+ Chodl+ GABAergic neuron HuBMAP Azimuth Cell Type Annotations 1.0 null Gustatory areas, layer 6b Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01238 superficial stratum of r2Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47825 Speech disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.062 osteoblasts BioGPS Mouse Cell Type and Tissue Gene Expression Profiles -1.0 -0.942877 496100611_FWM_no dementia_no TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.55895 animal TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 endomembrane system COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.529208 Axon hillock COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.52 superficial stratum of CoPD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03526 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.41398 Neocortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.351 H3K27me3_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Neurosecretory vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.128 dorsal thalamus_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.46539 Perturb_16302_KO_Esr1_SRP115139 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -5.92654 NCIH196 CCLE Cell Line Gene CNV Profiles -1.0 -1.5624 HUPT4 DepMap CRISPR Gene Dependency 1.0 6.04198 retrotrapezoid nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51506 apical dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.232744 GSE217378_2_v_0_lin28b_mouse RummaGEO Gene Perturbation Signatures 1.0 null abnormality of leukocytes GWASdb SNP-Phenotype Associations 1.0 0.081111 MDA-MB-157 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.23119 Mouse - Motor Cortex - Subclass - Sst+ GABAergic neuron HuBMAP Azimuth Cell Type Annotations 1.0 null AP1AR CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.4696 Pancreatic adenocarcinoma_PAAD_TCGA-H8-A6C1-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null r2 part of lateral pontine nuclei Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08842 H3K18ac_H9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null GSE171401_1_v_0_adnp_human RummaGEO Gene Perturbation Signatures -1.0 null superficial stratum of DG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40886 dentate gyrus mossy fiber COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.561772 Secretory vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 FLI1 ChEA Transcription Factor Targets 1.0 null Mouse - Motor Cortex - Cluster - Vip+ Gpc3+ GABAergic neuron HuBMAP Azimuth Cell Type Annotations 1.0 null ZNF263_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null HIVEP2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53707 Brain Lower Grade Glioma_LGG_TCGA-HT-8018-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cornu ammonis TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.884167 ChIP_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null breast carcinoma GWASdb SNP-Phenotype Associations 1.0 1.31194 hsa-miR-4252 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 COLO-818 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.32952 mantle zone of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08143 Synaptic vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.549 hsa-miR-1299 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.07142 NPIPA8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.24397 amygdaloid complex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.01011 H3K27me3_GM12878_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null posteroventral (inferior) parietal cortex_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.889231 PLCPRF5 CCLE Cell Line Gene CNV Profiles -1.0 -2.3514 periventricular stratum of r1Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43994 abnormality of renin-angiotensin system GWASdb SNP-Phenotype Associations 1.0 0.699708 whole body TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null diencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.078068 integral component of membrane GO Cellular Component Annotations 2015 1.0 null PMC7176284-pcbi.1007753.s008.xlsx-2_MYCN-NA_NBL_Multimodal_Genes-gene_MYCN Rummagene Transcription Factor Associations 2026 1.0 null GSE195514_0_v_1_stk25_human RummaGEO Gene Perturbation Signatures 1.0 null TAF15-26573619-CHIP-SEQ-HEK293-HUMAN ChEA Transcription Factor Targets 2022 1.0 null inner CP in rostral perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1319 Whole body TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Prelimbic cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.511 PANC0327 CCLE Cell Line Gene CNV Profiles 1.0 1.33731 ZNF263 ENCODE Transcription Factor Targets 1.0 null HCT116 Achilles Cell Line Gene Essentiality Profiles 1.0 1.45507 GSE88819_3_v_4_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Nucleus of the trapezoid body Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58244 anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.05316 PXR (PXR:RXR) MotifMap Predicted Transcription Factor Targets 1.0 null GTEX-X585-0011-R5A-SM-46MVI GTEx Tissue Sample Gene Expression Profiles 1.0 1.41459 GTEX-QDT8-0011-R6A-SM-32PKI GTEx Tissue Sample Gene Expression Profiles 1.0 1.00558 abducens nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.78906 Olfactory cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.28 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4969-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-WZTO-0011-R5B-SM-3NMC5 GTEx Tissue Sample Gene Expression Profiles 1.0 1.35966 Glutamate decarboxylase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.988 VASH1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.12953 MEF2C JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.684 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.826 GTEX-T2IS-2926-SM-32QPO GTEx Tissue Sample Gene Expression Profiles 1.0 1.0522 GSE228894_0_v_2_rnmt_mouse RummaGEO Gene Perturbation Signatures 1.0 null PMC4149371-pone.0105180.s010.xls-NANOG-GENE_NANOG Rummagene Transcription Factor Associations 2026 1.0 null Bipolar cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.044 Z chromosome COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.641 PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5 Rummagene Transcription Factor Associations 2026 1.0 null PITX3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.9498 HEV_60Day_None_GSE53731 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.92729 cytoplasmic part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 intracellular COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.314091 LRRC40 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.22089 BACH1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null pparb_23093780_pancreas_lof_mouse_gpl1261_gds4320 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.165846 Perirhinal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.978 POLR2A_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE238116_1_v_2_egr1_human RummaGEO Gene Perturbation Signatures -1.0 null amygdaloid complex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 2.75674 hsa-miR-147 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.99187 amygdaloid complex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10925 Brain Lower Grade Glioma_LGG_TCGA-S9-A6WI-01A-21R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cerebral lobe TISSUES Curated Tissue Protein Expression Evidence Scores 1.0 null Intellectual disability DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.467 inner CP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.838859 medial portion of the shell Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.10936 membrane part GO Cellular Component Annotations 2015 1.0 null Mitral cell layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.149 Connexin complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.098 autosomal genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.047639 arcuate nucleus of medulla, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.43071 Temporal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.176 Secretory vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.278 MYC ChEA Transcription Factor Targets 1.0 null lateral medullary reticular group, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34134 occipital neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.67246 H3K4me3_H7_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Rectum adenocarcinoma_READ_TCGA-AF-6672-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Accessory olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.62292 VIIIB, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.826025 abnormality of the coronary arteries GWASdb SNP-Phenotype Associations 1.0 0.262174 CHD2 ENCODE Transcription Factor Targets 1.0 null central nervous system TISSUES Experimental Tissue Protein Expression Evidence Scores 1.0 1.53602 laterostriatal stripe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.19225 HEC265 DepMap CRISPR Gene Dependency 1.0 3.44209 chr3_63345765_C_T_b38 GTEx eQTL 2025 1.0 1.0976 GSE214382,GSE214383_1_v_2_ascl1_human RummaGEO Gene Perturbation Signatures -1.0 null GTEX-WL46-0011-R5A-SM-3LK6V GTEx Tissue Sample Gene Expression Profiles 1.0 1.34935 hsa-let-7a-5p MiRTarBase microRNA Targets 1.0 null ZNF157 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.4254 dorsolateral part of Int Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.13608 Mouse - Motor Cortex - Cluster - Vip+ Serpinf1+ GABAergic neuron_3 HuBMAP Azimuth Cell Type Annotations 1.0 null olfactory nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.59405 Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AE-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.850691 periventricular stratum of Hb Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58813 PMC8709578-elife-69843-supp2.xlsx-MIX_Ctr-Nearest_Ensembl_MIXL1 Rummagene Transcription Factor Associations 2026 1.0 null LATS2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33387 MAX_H1-hESC_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-WL46-2926-SM-3LK82 GTEx Tissue Sample Gene Expression Profiles 1.0 0.848819 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Limbic system TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 TEAD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.6183 H3K27me3_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PMC12354803-42003_2025_8643_MOESM2_ESM.xlsx-2w_TP63_positive-Gene_TP63 Rummagene Transcription Factor Associations 2026 1.0 null 451LU COSMIC Cell Line Gene CNV Profiles 1.0 3.12177 GTEX-R55E-0011-R4A-SM-2TC5H GTEx Tissue Sample Gene Expression Profiles 1.0 1.07615 NR2C1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.7969 Sarcoma_SARC_TCGA-DX-A3U9-01A-11R-A30C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.882897 GSE199874_3_v_5_gabpb1_mouse RummaGEO Gene Perturbation Signatures 1.0 null claustrum, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.54425 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.848325 Kidney Chromophobe_KICH_TCGA-KO-8415-01A-11R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Specific developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.586 Axon terminus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.019 H3K4me1_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null integral component of synaptic vesicle membrane SynGO Synaptic Gene Annotations 1.0 null NCI-H2803 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.865538 developmental disorder of mental health GWASdb SNP-Disease Associations 1.0 0.220246 Cerebral hemisphere TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 PMC12616242-can-24-3452_supplementary_table_s6_suppst6.xlsx-EWSR1FLI1-KDM6B-targets_down-EWSR1_FLI1-KDM6B_downregulated_targets_upon_KDM6B_knockout_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null U118MG CCLE Cell Line Gene CNV Profiles 1.0 1.49683 GTEX-NL3H-0011-R10A-SM-2I3E9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05007 CD33+_Myeloid BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -0.909979 GTEX-UTHO-3026-SM-3GAFB GTEx Tissue Sample Gene Expression Profiles 1.0 0.950395 Huntington's Disease_Lymphocyte_GSE8762 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.52978 NRF1 ENCODE Transcription Factor Targets 1.0 null RFX5 ENCODE Transcription Factor Targets 1.0 null Medial mammillary nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.15 Primary dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.054 terminal bouton COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.525113 nucleus of the lateral olfactory tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.25071 organ system cancer GWASdb SNP-Disease Associations 1.0 0.112571 PBX1-22567123-OVCAR3-HUMAN ChEA Transcription Factor Targets 2022 1.0 null tobacco use disorder GAD Gene-Disease Associations 1.0 null GSE184902_4_v_1_adiponectin_mouse RummaGEO Drug Perturbation Signatures -1.0 null Eye TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 intracellular part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GSE111138,GSE111149_1_v_3_runx3_mouse RummaGEO Gene Perturbation Signatures -1.0 null PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-Unnamed_2_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null Intrinsic component of synaptic vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.478 Tal-1alpha:E47 MotifMap Predicted Transcription Factor Targets 1.0 null SKRC20 CCLE Cell Line Gene Expression Profiles -1.0 -1.70988 JAR COSMIC Cell Line Gene Mutation Profiles 1.0 null membrane-bounded vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 MAX ENCODE Transcription Factor Targets 1.0 null Apical dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.517 Fascia dentata TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.302 GTEX-XOTO-0011-R11B-SM-4B64O GTEx Tissue Sample Gene Expression Profiles 1.0 1.21252 Mouse - Motor Cortex - Cross-Species Cluster - Vip+ GABAergic neuron_2 HuBMAP Azimuth Cell Type Annotations 1.0 null External plexiform layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.565 CNP CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.04998 RARA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 59.6252 GSE138001_5_v_4_rorb_mouse RummaGEO Gene Perturbation Signatures 1.0 null EZH2_GM12878_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null lower respiratory tract disease GWASdb SNP-Disease Associations 1.0 0.363945 496100616_FWM_no dementia_TBI_84_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.58254 POLR2A_olfactory bulb_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-IB-8126-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Perturb_14982_KO_Setd1a_SRP330236 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.98952 Pervasive developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.608 tissues, cell types and enzyme sources TISSUES Curated Tissue Protein Expression Evidence Scores 2025 1.0 4.0 Tetanus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.161 organelle part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.049492 cerebral lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.838672 JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.7253 IGR-37 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.920409 dorsolateral prefrontal cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.4261 inferior olive, principal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.85245 NKX2-8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5548 PMC9181267-mmc3.xls-FILTERED_OLD-INFvsYOUNG-INF_LUN-GSEA_name_TOPORS Rummagene Transcription Factor Associations 2026 1.0 null intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 abnormality of the oral cavity GWASdb SNP-Phenotype Associations 1.0 0.125146 Perturb_14667_KO_Sirt3_SRP277814 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 10.8263 Exocytic vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 Integral component of synaptic vesicle membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.577 abnormality of the vasculature GWASdb SNP-Phenotype Associations 1.0 0.078364 GTEX-PVOW-0011-R1A-SM-32PL6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.23134 membrane LOCATE Predicted Protein Localization Annotations 1.0 null HCC78 DepMap CRISPR Gene Dependency 1.0 9.4518 H3K4me3_WERI-Rb-1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-EJ-A8FU-01A-11R-A36G-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mantle zone of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.34556 GSE216273,GSE216292_14_v_8_palbociclib_human RummaGEO Drug Perturbation Signatures 1.0 null SNARE complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.257 basomedial amygdaloid nucleus, anterior part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13686 MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null Principal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.019 cellular_component GO Cellular Component Annotations 2015 1.0 null GTEX-WL46-0011-R1A-SM-3LK6M GTEx Tissue Sample Gene Expression Profiles 1.0 0.885584 PMC6590191__F3 PFOCR Pathway Figure Associations 2024 1.0 null induced GeneRIF Biological Term Annotations 1.0 null GSE150669_0_v_1_roxadustat_mouse RummaGEO Drug Perturbation Signatures -1.0 null cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null ESCO1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.59925 H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null neurodegenerative disease GWASdb SNP-Disease Associations 1.0 0.27808 GTEX-R55E-0011-R5A-SM-2TC5N GTEx Tissue Sample Gene Expression Profiles 1.0 1.23164 Brain Lower Grade Glioma_LGG_TCGA-HT-A5R7-01A-11R-A28M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-TSE9-0011-R7A-SM-3DB7P GTEx Tissue Sample Gene Expression Profiles 1.0 0.956369 GTEX-XOTO-0011-R1B-SM-4B65C GTEx Tissue Sample Gene Expression Profiles 1.0 1.05061 WM983B CCLE Cell Line Gene CNV Profiles 1.0 2.43568 GTEX-WZTO-2826-SM-3NM8P GTEx Tissue Sample Gene Expression Profiles 1.0 1.01877 T24 DepMap CRISPR Gene Dependency 1.0 5.08325 NR4A2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.3246 cbp_cpb heterozygous mice_GSE30880_328_mouse_Hippocampus GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PROP1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.9812 r3 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.82158 H3K4me2_H1-hESC_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null outer CP in ventrolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.839211 LOUNH91 DepMap CRISPR Gene Dependency 1.0 2.01306 Learning Disorders CTD Gene-Disease Associations 1.0 1.17629 GTEX-RU72-0011-R6A-SM-2TF71 GTEx Tissue Sample Gene Expression Profiles 1.0 1.342 Main olfactory bulb, granule layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.99426 Presynaptic endocytic zone COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.563 ETV5::FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.6166 Atrioventricular node TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.502 WT1-25993318-PODOCYTE-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Mood disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.454 Prostate adenocarcinoma_PRAD_TCGA-HC-8265-01A-11R-2263-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HS766T Achilles Cell Line Gene Essentiality Profiles -1.0 -1.44245 H3K27me3_cardiac mesoderm_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Prostate adenocarcinoma_PRAD_TCGA-VN-A88I-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null cochlear nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.47519 PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null NRL_Deficiency_GDS1693_239_mouse_Photoreceptors cells of retinas at 4 weeks GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Medial entorhinal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.529 PMC10123531-NIHMS1874945-supplement-Table_S3.xlsx-SOX17_BCAT_cobound_coreg_peaks-Gene_Name_SOX17 Rummagene Transcription Factor Associations 2026 1.0 null GSE178255_2_v_7_tlr4_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE210101,GSE210114_8_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null intracellular organelle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 ZNF708 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.3793 outer CP in (rostral) midinferior temporal cortex (area 36) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.00478 RBBP5 ENCODE Transcription Factor Targets 1.0 null Cerebral hemisphere TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.208 C3A CCLE Cell Line Gene Expression Profiles -1.0 -1.91546 GTEX-NPJ7-0011-R11A-SM-2I3E8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.09257 GTEX-UTHO-0011-R11A-SM-3GIJE GTEx Tissue Sample Gene Expression Profiles 1.0 1.3811 neoplasm GWASdb SNP-Phenotype Associations 1.0 0.101787 abnormality of body height GWASdb SNP-Phenotype Associations 1.0 0.67307 primary motor cortex (area M1, area 4)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.827336 Perturb_12546_KO_Shank2_SRP309197 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 1.39305 Dementia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.333 H3K4me3_MCF-7_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null SIMA CCLE Cell Line Gene Expression Profiles 1.0 1.69766 release GeneRIF Biological Term Annotations 1.0 null COLO849 CCLE Cell Line Gene CNV Profiles 1.0 1.45626 VMRCLCD DepMap CRISPR Gene Dependency 1.0 3.322 lateral part of Med Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09031 GSE205163,GSE205164_2_v_6_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null integral component of synaptic vesicle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Brain Lower Grade Glioma_LGG_TCGA-FG-5965-02B-11R-A29R-07,TCGA-FG-5965-02A-11R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null brain stem TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.289939 pinealocyte TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.394576 interleukin-27 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.200328 PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8 Rummagene Transcription Factor Associations 2026 1.0 null CPC-N Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.29405 hsa-miR-19b TargetScan Predicted Conserved microRNA Targets 1.0 0.127531 X-linked dominant disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.108 ETV6 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.10144 Mouse - Motor Cortex - Cluster - Vip+ Chat+ GABAergic neuron_2 HuBMAP Azimuth Cell Type Annotations 1.0 null ZNF317 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.7646 estradiol_mus musculus_gpl4134_gse23072 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null brain HPA Tissue Gene Expression Profiles 1.0 1.6695 medial (main) part of Med Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03324 cytoplasmic vesicle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CTCF_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null peripheral nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.41848 H3K27me3_H1 BMP4 Derived Trophoblast Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Lateral dorsal nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.535 Flocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.10405 hsa-miR-337-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.2992 GSE68156_3_v_5_dextran_mouse RummaGEO Drug Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-DU-A7TC-01A-21R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.24752 cytoplasm COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.443292 metal metabolism disorder GWASdb SNP-Disease Associations 1.0 0.679818 alzheimer disease GWASdb SNP-Phenotype Associations 1.0 0.569663 Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6962-01A-11R-1915-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-PWO3-0011-R3A-SM-2I5EX GTEx Tissue Sample Gene Expression Profiles 1.0 1.03866 Gland TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.764 NANOG-16153702-HESC-human ChEA Transcription Factor Binding Site Profiles 1.0 null H3K27me3_Brain Mid Frontal Lobe Roadmap Epigenomics Histone Modification Site Profiles 1.0 null CHD1 ENCODE Transcription Factor Targets 1.0 null plant TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.539793 C13orf42 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42391 DHX8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.04316 GSE213588_10_v_5_trametinib_human RummaGEO Drug Perturbation Signatures 1.0 null VZ in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14162 MYC-19915707-AK7-human ChEA Transcription Factor Binding Site Profiles 1.0 null Somatodendritic compartment COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.993 HOXC8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 13.0572 dexamethasone_mus musculus_gpl5137_gse10900 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null OB mitral cell layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.87362 GTEX-T2IS-0011-R5A-SM-32QP4 GTEx Tissue Sample Gene Expression Profiles 1.0 2.22132 GSE144231_3_v_5_cxcr2_mouse RummaGEO Gene Perturbation Signatures 1.0 null synaptophysin GeneRIF Biological Term Annotations 1.0 null superficial stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.06368 anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13155 GSE119498_0_v_10_setd5_mouse RummaGEO Gene Perturbation Signatures 1.0 null Perturb_14006_KO_Perk_SRP370072 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 10.3725 lateral medullary reticular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34482 lateral group of nuclei, right, ventral division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.829457 PMC4383005-ncomms7500-s4.xlsx-MinusSpecific_filteredGenes-Supplementary_Data_3_HES5-_vs_HES5_expression_intensity_ratios_during_NSC_progression_HES5 Rummagene Transcription Factor Associations 2026 1.0 null Kidney Chromophobe_KICH_TCGA-KN-8437-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-R55F-1226-SM-2TF59 GTEx Tissue Sample Gene Expression Profiles 1.0 1.12643 cytoplasmic membrane-bounded vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.962627 Perturb_14003_OE_Kcna2_SRP309478 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -7.8486 GSE201520_8_v_3_inhba_mouse RummaGEO Gene Perturbation Signatures -1.0 null TWIST1_01_252 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.41925 superficial stratum of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01171 HAUS3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.39537 EZH2_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null parietal neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.60178 SKMEL24 DepMap CRISPR Gene Dependency 1.0 2.98182 PMC8387919-mmc2.xlsx-ST8_NEUROG3_and_islets_expr-Unnamed_4_NEUROG3 Rummagene Transcription Factor Associations 2026 1.0 null ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.60088 GSE223008_9_v_8_calhm6_mouse RummaGEO Gene Perturbation Signatures 1.0 null impairment GeneRIF Biological Term Annotations 1.0 null cytoplasmic part GO Cellular Component Annotations 2015 1.0 null GTEX-QVUS-0011-R10A-SM-3GIK3 GTEx Tissue Sample Gene Expression Profiles 1.0 0.993295 amygdaloid complex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.910367 FOXO6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9792 Amelogenesis imperfecta type 1B DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.446 Ventral posteromedial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12066 membrane-bounded organelle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.446465 MEL270 DepMap CRISPR Gene Dependency 1.0 3.35994 fallopian tube GTEx Tissue Gene Expression Profiles -1.0 -1.10082 hsa-miR-4689 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Lingula (I), molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05188 NR1H2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.8 DMS 454 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.17509 Huntington's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.118 GTEX-Q2AG-0011-R10A-SM-2HMLA GTEx Tissue Sample Gene Expression Profiles 1.0 0.937547 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null mRNA_MYCN_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null asthma GWASdb SNP-Phenotype Associations 1.0 0.825497 GTEX-UTHO-2926-SM-3P5Z9 GTEx Tissue Sample Gene Expression Profiles 1.0 1.0203 axon COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.40247 Epithalamus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.192 H3K27me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null cingulum bundle, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.02101 intracellular organelle LOCATE Curated Protein Localization Annotations 1.0 null UCSD-242L Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14724 H3K27me3_keratinocyte_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-QMR6-0011-R11A-SM-32PKK GTEx Tissue Sample Gene Expression Profiles 1.0 1.20741 FXR MotifMap Predicted Transcription Factor Targets 1.0 null HOXD8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.1327 vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 GTEX-WHSE-0011-R7A-SM-3P5YZ GTEx Tissue Sample Gene Expression Profiles 1.0 1.21558 ZNF85 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.7003 ETV2::FIGLA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.5352 ARPP19 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.54529 USF3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.17151 Frontal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.926 CEBPB-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE256181_2_v_3_etv2_human RummaGEO Gene Perturbation Signatures 1.0 null GSE205163,GSE205164_1_v_7_znf808_human RummaGEO Gene Perturbation Signatures -1.0 null GSE71491_0_v_1_cyclophosphamide_mouse RummaGEO Drug Perturbation Signatures 1.0 null H3K27me3_mammary epithelial cell_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null abnormality of metabolism/homeostasis GWASdb SNP-Phenotype Associations 1.0 1.51253 TCF4-22108803-LS180-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Temporal lobe epilepsy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.023 Avian pallium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.515 PPAR-Beta_DELETION_GDS4320_363_mouse_Pancreatic beta-cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Orbital area, medial part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00645 GSE81803,GSE81912_0_v_5_fmr1_mouse RummaGEO Gene Perturbation Signatures -1.0 null SUPT6H CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -3.35422 Cerebellum TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.509 hsa-miR-4531 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Claustrum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.13319 GTEX-WHSE-0011-R1A-SM-3P5ZK GTEx Tissue Sample Gene Expression Profiles 1.0 1.22115 mRNA_SOX9_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null PMC6938365-pone.0226733.s020.txt--NANOG_NANOG Rummagene Transcription Factor Associations 2026 1.0 null ZNF331 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.12109 Dentate gyrus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44677 184B5 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.714512 Pheochromocytoma and Paraganglioma_PCPG_TCGA-S7-A7WR-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BHLHE22 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.2611 abnormality of the systemic arterial tree GWASdb SNP-Phenotype Associations 1.0 0.110159 GSE256181_1_v_3_etv2_human RummaGEO Gene Perturbation Signatures 1.0 null Integrin alpha7-beta1 complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.693 growth abnormality GWASdb SNP-Phenotype Associations 1.0 0.35116 GTEX-XLM4-0011-R6A-SM-4AT4B GTEx Tissue Sample Gene Expression Profiles 1.0 2.14604 GSE210101,GSE210114_8_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null hsa-miR-4682 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.809003 Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.873 Asymmetric synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.636 EZH2_endothelial cell of umbilical vein_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV6-01A-21R-A37K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CTCF_H1-hESC_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CC-06A-11R-A18S-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Dentate granule cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.74 GSE195559_6_v_1_notch1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-N7MS-0011-R3a-SM-33HC6 GTEx Tissue Sample Gene Expression Profiles 1.0 1.13147 GSE68156_0_v_1_dextran_mouse RummaGEO Drug Perturbation Signatures -1.0 null Gastrinoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.854 PRSS8 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.42663 head of caudate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.33565 Transport vesicle COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 TBP ENCODE Transcription Factor Targets 1.0 null cytoplasmic vesicle part GO Cellular Component Annotations 2015 1.0 null GTEX-NPJ7-0011-R10A-SM-2I3E5 GTEx Tissue Sample Gene Expression Profiles 1.0 0.974449 Hippocampus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.169 SOX2-16153702-HESC-human ChEA Transcription Factor Binding Site Profiles 1.0 null CAL51 Achilles Cell Line Gene Essentiality Profiles 1.0 2.77071 external part of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.60939 PMC7608835-aba3058_Table_S3.xlsx-324_RING1B-FLI1_notH2Aub-Genes_containing_RING1B_EWSR1-FLI1_peaks_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null Nidopallium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.543 r6 part of the cochlear column Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47215 ISL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.3339 hsa-miR-3617 TargetScan Predicted Nonconserved microRNA Targets 1.0 0.921135 EP300 ENCODE Transcription Factor Targets 1.0 null Weight Gain CTD Gene-Disease Associations 1.0 1.01437 TP53_01_37 KnockTF Gene Expression Profiles with Transcription Factor Perturbations 1.0 1.73614 bipolar cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.335968 Prostate adenocarcinoma_PRAD_TCGA-YL-A8SP-01B-11R-A37L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC1011 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.28482 GSE223008_5_v_8_calhm6_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K4me1_lung_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Major depressive disorder GWAS Catalog SNP-Phenotype Associations 2025 1.0 0.522185 hsa-miR-34c-3p TargetScan Predicted Nonconserved microRNA Targets 1.0 1.0155 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A57G-01A-11R-A26T-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE89057_0_v_1_sox5_human RummaGEO Gene Perturbation Signatures 1.0 null GSE210101,GSE210114_2_v_9_urod_human RummaGEO Gene Perturbation Signatures -1.0 null posteroventral (inferior) parietal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.865757 integral component of organelle membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CAL33 CCLE Cell Line Gene CNV Profiles -1.0 -1.46885 PMC7801680-41598_2020_79740_MOESM9_ESM.xlsx-STAT3_target_genes_in_N1-GOPC_STAT3 Rummagene Transcription Factor Associations 2026 1.0 null pineal body Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.13685 NAMALWA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.2534 DHX32 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.4326 MYC-19915707-AK7-HUMAN ChEA Transcription Factor Targets 2022 1.0 null mantle zone of AOV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01171 metencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.252261 Synaptic membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.575 Main olfactory bulb, glomerular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63827 red nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.24704 gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052843 GSE88819_3_v_10_tug1_mouse RummaGEO Gene Perturbation Signatures -1.0 null Drug-Induced Liver Injury CTD Gene-Disease Associations 1.0 1.05573 hsa-miR-1272 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.40969 PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_16_TEAD1 Rummagene Transcription Factor Associations 2026 1.0 null G140 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.957685 Nucleus of the lateral olfactory tract, pyramidal layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40602 all GWASdb SNP-Phenotype Associations 1.0 0.09523 primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.25634 GSE210101,GSE210114_5_v_3_urod_human RummaGEO Gene Perturbation Signatures -1.0 null TFAP4::ETV1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.9694 Neurodegenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.599 PMC6938365-pone.0226733.s018.txt--CTCF_CTCF Rummagene Transcription Factor Associations 2026 1.0 null GSE96641_3_v_4_esrp2_mouse RummaGEO Gene Perturbation Signatures 1.0 null Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A465-01A-11R-A266-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Type II site-specific deoxyribonuclease complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.629 CSTB_KO_GDS5090_200_mouse_Cerebellar granule cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null GTEX-WL46-0011-R3A-SM-3TW8E GTEx Tissue Sample Gene Expression Profiles 1.0 0.882426 GTEX-QVUS-0011-R1A-SM-3GAD2 GTEx Tissue Sample Gene Expression Profiles 1.0 0.850603 CDK16 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.20877 OTX2_silencing_GDS4472_136_human_D425 medulloblastoma (MB) cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null HOXA5 JASPAR Predicted Transcription Factor Targets 1.0 null GTEX-WWYW-0011-R5A-SM-3NB3E GTEx Tissue Sample Gene Expression Profiles 1.0 1.36241 FLI1-21571218-MEGAKARYOCYTES-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null GSE92457_9_v_10_ethanol_mouse RummaGEO Drug Perturbation Signatures 1.0 null GTEX-T5JC-2326-SM-32PMR GTEx Tissue Sample Gene Expression Profiles 1.0 1.05557 Terminal bouton COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.131 Basal dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.524 GET3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.0161 laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.879998 orbital frontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.859299 shoot TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.665588 periventricular stratum of Pal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.05733 posterior part of Int Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.81844 hsa-miR-410 TargetScan Predicted Conserved microRNA Targets 1.0 0.766596 orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.29179 cerebellar cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.825309 TEAD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1879 cell projection GO Cellular Component Annotations 2015 1.0 null GTEX-S7SE-0011-R1A-SM-2XCDE GTEx Tissue Sample Gene Expression Profiles 1.0 1.05291 GTEX-PVOW-0011-R5A-SM-32PL7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.61919 granular vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.35899 avian pallium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.164629 H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null SMARCA4 ChEA Transcription Factor Targets 1.0 null outer plexiform layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.396844 GTEX-QVUS-0011-R3A-SM-3GAFD GTEx Tissue Sample Gene Expression Profiles 1.0 1.29976 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LH-01A-21R-A213-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null UBXN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.1652 Perturb_14724_KO_Dicer_SRP082704 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations 1.0 5.63695 lower (caudal) rhombic lip Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -3.0829 facial motor nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.06687 GSE210101,GSE210114_6_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null Juxtaglomerular apparatus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.943 GTEX-XLM4-0011-R7A-SM-4AT5L GTEx Tissue Sample Gene Expression Profiles 1.0 1.39008 RORA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.2111 inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12890 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 0.858156 acquired metabolic disease GWASdb SNP-Disease Associations 1.0 0.374637 TMEM120A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.76704 A_CA_04_2009_7dayMOI-10^4_None_GSE37569 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.54097 GTEX-R55E-0011-R1A-SM-2TC6N GTEx Tissue Sample Gene Expression Profiles 1.0 1.01756 Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A708-01A-11R-A35K-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Tcf12 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.3792 H3K4me3_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null anterior group of nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.23969 lateral group of nuclei, left, dorsal division Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04567 TRIM28-17542650-NTERA2-HUMAN ChEA Transcription Factor Targets 2022 1.0 null intermediate stratum of AOB Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.05389 Striatal neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.933 H3K4me3_iPS DF 6.9 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null e2f1_21245101_mmtv-myc_lof_mouse_gpl8321_gds4094 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations -1.0 -0.118732 Accessory outer segment COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.198 Hypolemmal cisterna COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.507 PMC7415402-oncotarget-11-2995-s004.xlsx-EWS-FLI1_Type_2_vs_Type_3-Gene_Symbol_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null Urinary system TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.946 lung disease GWASdb SNP-Disease Associations 1.0 0.686305 PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_1h-Nearest_Ensembl_HSF1 Rummagene Transcription Factor Associations 2026 1.0 null pontine nuclei, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.34108 transport GO Biological Process Annotations 2015 1.0 null Synapse COMPARTMENTS Curated Protein Localization Evidence Scores 2025 1.0 3.0 brain GTEx Tissue Gene Expression Profiles 1.0 2.18987 primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.15712 E2F6_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Parkinson's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.203 primary motor-sensory cortex (samples)_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -2.01646 Smoking DisGeNET Gene-Phenotype Associations 1.0 null Synaptic cleft COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.183 E2F6_H1-hESC_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null neuron projection COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 granule cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.856312 496100330_PCx_possible Alzheimer's disease_no TBI_100+_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles -1.0 -2.18502 GABA-A receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.51 carbohydrate metabolism disease GWASdb SNP-Disease Associations 1.0 0.454501 SZ in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.881849 Basolateral amygdalar nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08855 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.06271 doxorubicin_homo sapiens_gpl570_gse46493 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null dorsolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.01521 hsa-miR-580 TargetScan Predicted Conserved microRNA Targets 1.0 1.11641 layer VI of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.26665 hsa-miR-181d TargetScan Predicted Conserved microRNA Targets 1.0 1.26663 Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MS-01A-11R-A35L-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Lewy neurite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.52 Anterior olfactory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15064 layer V of area 35c Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0484 obsessive-compulsive personality disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.554 LANCL1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.06871 GSE133763_0_v_2_chd1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-RVPV-0011-R11A-SM-2TF6F GTEx Tissue Sample Gene Expression Profiles 1.0 1.20445 cerebellar nuclei of CbH Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.49992 H3K4me1_testis_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null fascia dentata TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.851266 3-methylglutaconic aciduria type 1 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.074 PMC3950952-154946.f1.pdf-6-MYBL1_MYBL1 Rummagene Transcription Factor Associations 2026 1.0 null EZH2_fibroblast of dermis_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null MCF7 DepMap CRISPR Gene Dependency 1.0 3.94651 H3K9ac_NT2-D1_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null r7 part of nucleus prepositus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.172 Paracentral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45914 NURR1 MotifMap Predicted Transcription Factor Targets 1.0 null Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GSE57397,GSE57399_1_v_0_fbxw7_human RummaGEO Gene Perturbation Signatures 1.0 null GABA receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.678 GSE148494,GSE182513_1_v_0_hoxd13_human RummaGEO Gene Perturbation Signatures 1.0 null PMC12068594-pgen.1011693.s007.xlsx-MCR_vs_MCB-gene_id_NR3C2 Rummagene Transcription Factor Associations 2026 1.0 null KYSE70 CCLE Cell Line Gene CNV Profiles 1.0 1.42375 HCC95 CCLE Cell Line Gene Expression Profiles -1.0 -1.73321 parietal neocortex_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.81896 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.580818 H3K4me3_cardiac mesoderm_hg19_3 ENCODE Histone Modification Site Profiles 1.0 null TEAD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0789 E2F1 JASPAR Predicted Transcription Factor Targets 1.0 null frontal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.385143 PMC8528285-pbio.3001085.s010.xlsx-Fig_8C-MLX_3T3_MLX Rummagene Transcription Factor Associations 2026 1.0 null RT112 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.8294 CIDEC_KO_GDS3776_552_mouse_Brown and white adipose tissues GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null H2AFZ ENCODE Transcription Factor Targets 1.0 null Olfactory bulb TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.97 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.848041 superior colliculus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.890272 PIGC CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.20846 HCA1 DepMap CRISPR Gene Dependency 1.0 3.97595 H3K9me3_CD14-positive monocyte_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null TTI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.31371 synapse part GO Cellular Component Annotations 2015 1.0 null GSE184902_4_v_1_adipor1_mouse RummaGEO Gene Perturbation Signatures -1.0 null LTBR_INHIBITION - 35 Day_GDS2004_737_mouse_Lymph nodes (MG-430A) GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null Inhibitory synapse COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.466 inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.10925 NCIH28 CCLE Cell Line Gene CNV Profiles 1.0 1.55234 temporal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.44021 A-673 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.17689 basomedial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.903293 GSE184902_4_v_0_adiponectin_mouse RummaGEO Drug Perturbation Signatures 1.0 null GSE111660_2_v_5_prdm16_mouse RummaGEO Gene Perturbation Signatures -1.0 null parvicellular part of Lat Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55615 GTEX-QVJO-0011-R10A-SM-2S1QJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.11362 H3K4me2_fibroblast of dermis_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null intracellular part LOCATE Curated Protein Localization Annotations 1.0 null GTEX-S7SE-0011-R10A-SM-2XCDF GTEx Tissue Sample Gene Expression Profiles 1.0 1.03225 cloning GeneRIF Biological Term Annotations 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TM-A84R-01A-21R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-NL4W-0011-R6a-SM-2I3GA GTEx Tissue Sample Gene Expression Profiles 1.0 1.6013 GSE149035_2_v_0_hepacam_human RummaGEO Gene Perturbation Signatures 1.0 null GSE101112_0_v_2_j147_mouse RummaGEO Drug Perturbation Signatures 1.0 null IKZF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.6303 Cul2-RING ubiquitin ligase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.544 r2 part of the trigeminal motor nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05857 horizontal cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.497266 superficial stratum of r3Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51028 superficial dorsofrontal area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03592 GTEX-QVJO-0011-R5A-SM-2S1QM GTEx Tissue Sample Gene Expression Profiles 1.0 1.44852 Perturb_4180_KO_Tsc1_SRP279018 PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations -1.0 -1.63538 Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.007 POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null HNF4A JASPAR Predicted Transcription Factor Targets 1.0 null COLO 857 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.18476 H3K4me3_WERI-Rb-1_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null PMC10528072-NIHMS1928302-supplement-5.xlsx-NEUROD1-target_genes-AANAT_NEUROD1 Rummagene Transcription Factor Associations 2026 1.0 null GSE210101,GSE210114_1_v_10_urod_human RummaGEO Gene Perturbation Signatures -1.0 null Lingula (I) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00477 primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.34347 TTC1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.35869 GSE205163,GSE205164_3_v_6_znf808_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-Q2AG-2826-SM-2HMJQ GTEx Tissue Sample Gene Expression Profiles 1.0 0.989818 REST ENCODE Transcription Factor Targets 1.0 null PF-382 COSMIC Cell Line Gene Mutation Profiles 1.0 null MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.363 cerebellar cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.2267 embryonic stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.214954 neuron part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.535361 abnormality of immune serum protein physiology GWASdb SNP-Phenotype Associations 1.0 0.628781 PF4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.15296 anterior amygdaloid area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.19038 telencephalon TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.790628 Presynaptic density COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.577 cerebral cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.799375 Brain Diseases CTD Gene-Disease Associations 1.0 1.17959 COLO 853 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-OHPN-0011-R5A-SM-2I5FF GTEx Tissue Sample Gene Expression Profiles 1.0 1.21403 hsa-miR-298 TargetScan Predicted Nonconserved microRNA Targets 1.0 1.55165 Learning disability DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.191 Interposed nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.78964 NANOG ChEA Transcription Factor Targets 1.0 null GTEX-QVUS-2926-SM-3GIJB GTEx Tissue Sample Gene Expression Profiles 1.0 1.1362 exocytic vesicle membrane GO Cellular Component Annotations 2023 1.0 null VZ in thalamic region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.18043 BJHTERT CCLE Cell Line Gene Expression Profiles -1.0 -2.42928 LTBR_INHIBITION - 3 Day_GDS2004_735_mouse_Lymph nodes (MG-430A) GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null striatum_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.38045 Deutocerebrum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.356 UGT3A2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.16296 PMC12297505-41598_2025_11704_MOESM4_ESM.xlsx-table_s4_veen-GSE16011_AND_TCGA-GBMLGG_NOT_Human_kinases_NR4A2 Rummagene Transcription Factor Associations 2026 1.0 null cytoplasmic vesicle COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.957352 intermediate stratum of r6BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56712 primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -0.942969 PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR Rummagene Transcription Factor Associations 2026 1.0 null Glucagonoma cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.652 Integral component of postsynaptic specialization membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.667 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.89451 GTEX-PWO3-0011-R6A-SM-2I5F3 GTEx Tissue Sample Gene Expression Profiles 1.0 1.01597 olfactory glomerulus TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.14476 MXI1 ENCODE Transcription Factor Targets 1.0 null superficial stratum of r4BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18818 SMARCA4-23332759-OLIGODENDROCYTES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null skin TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.062857 Nucleus of the lateral olfactory tract, layer 3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.63257 mood disorder GWASdb SNP-Disease Associations 1.0 0.339328 Superior vestibular nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.53 inner nuclear layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.361901 inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.11405 lateral subdivision of area 9 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.906845 MXI1_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-RVPV-0011-R3A-SM-2TF63 GTEx Tissue Sample Gene Expression Profiles 1.0 0.985613 LN-18 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.854592 GSE230263,GSE230265_5_v_1_runx1_human RummaGEO Gene Perturbation Signatures 1.0 null PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2 Rummagene Transcription Factor Associations 2026 1.0 null GTEX-WZTO-2926-SM-3NM9I GTEx Tissue Sample Gene Expression Profiles 1.0 0.885658 GTEX-WVLH-0011-R2A-SM-3MJFJ GTEx Tissue Sample Gene Expression Profiles 1.0 1.04763 Serum Albumin Measurement DisGeNET Gene-Phenotype Associations 1.0 null GTEX-Q2AG-0011-R6A-SM-2HML7 GTEx Tissue Sample Gene Expression Profiles 1.0 1.56389 disease of anatomical entity GWASdb SNP-Disease Associations 1.0 0.077374 abducens nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.4593 UOK101 DepMap CRISPR Gene Dependency 1.0 2.18713 Tobacco Use Disorder HuGE Navigator Gene-Phenotype Associations 1.0 null ventral posteromedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39726 Rostral migratory stream TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.758 OB inner plexiform layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.87745 Caudatenucleus BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.77016 A3KAW CCLE Cell Line Gene CNV Profiles 1.0 1.43584 Olfactory tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.959 primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq -1.0 -1.00194 Mouse - Motor Cortex - Cluster - Vip+ Chat+ GABAergic neuron_1 HuBMAP Azimuth Cell Type Annotations 1.0 null striatum_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq 1.0 1.67296 Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TF-01A-52R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FLI1-21867929-TH2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GTEX-WHSE-0011-R6A-SM-3P5ZP GTEx Tissue Sample Gene Expression Profiles 1.0 1.44374 respiratory mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.179022 GSE101239_5_v_0_valproic acid_mouse RummaGEO Drug Perturbation Signatures -1.0 null GSE164757,GSE164759_1_v_3_trametinib_mouse RummaGEO Drug Perturbation Signatures -1.0 null intracellular part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.339261 nucleus accumbens, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.08941 SOX2-16153702-HESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null GSE111660_4_v_3_prdm16_mouse RummaGEO Gene Perturbation Signatures 1.0 null GSE217363_4_v_1_nlrp3_mouse RummaGEO Gene Perturbation Signatures 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7694-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null SMARCD1-25818293-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null GSE196104,GSE196106_2_v_1_vsx2_mouse RummaGEO Gene Perturbation Signatures 1.0 null H3K27me3_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null GTEX-XLM4-2926-SM-4AT59 GTEx Tissue Sample Gene Expression Profiles 1.0 0.978338 Rectum adenocarcinoma_READ_TCGA-EI-6509-01A-11R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null huntington's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.703134 GSE96641_5_v_0_esrp2_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney Chromophobe_KICH_TCGA-KN-8428-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GTEX-XMD1-0011-R5A-SM-4AT47 GTEx Tissue Sample Gene Expression Profiles 1.0 1.16032 CEBPB-26923725-CHIP-SEQ-HEMANGIOBLAST-MOUSE ChEA Transcription Factor Targets 2022 1.0 null abnormality of the nervous system GWASdb SNP-Phenotype Associations 1.0 0.734978 WM115 CCLE Cell Line Gene Expression Profiles -1.0 -1.83754 NCIH1694 CCLE Cell Line Gene Expression Profiles 1.0 1.45485 cytoplasm COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.44052 Subthalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.759 SPRYD7 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.33211 SP in posterior parahippocampal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.906442 HDAC2 ENCODE Transcription Factor Targets 1.0 null GTEX-QMR6-0011-R10A-SM-32PKO GTEx Tissue Sample Gene Expression Profiles 1.0 1.06282 H3K4me3_H1 BMP4 Derived Mesendoderm Cultured Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null PMC9170821-JCMM-26-3183-s001.xlsx-Macro_DAPI_ERG_VaD_vs_NC-Gene_ERG Rummagene Transcription Factor Associations 2026 1.0 null ZNF143 ENCODE Transcription Factor Targets 1.0 null Thorny excrescence COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 2.329 EWSR1-FLI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 108.229 SK-MEL-28 COSMIC Cell Line Gene CNV Profiles 1.0 3.12177 GTEX-NL3H-0011-R5a-SM-2I3GB GTEx Tissue Sample Gene Expression Profiles 1.0 0.977859 lymphoblastic leukemia GWASdb SNP-Disease Associations 1.0 0.399697 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.053387 ATOH7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7017 respiratory system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057077 CORL51 CCLE Cell Line Gene Expression Profiles 1.0 1.37246 GSE195559_8_v_1_notch1_human RummaGEO Gene Perturbation Signatures 1.0 null GTEX-N7MS-0011-R11A-SM-2HMJS GTEx Tissue Sample Gene Expression Profiles 1.0 1.2963 PMC11801220-NIHMS2038999-supplement-16.xlsx-Inh-MEF2C-gene_MEF2C Rummagene Transcription Factor Associations 2026 1.0 null REST_SK-N-SH_hg19_4 ENCODE Transcription Factor Binding Site Profiles 1.0 null GSE119498_2_v_4_setd5_mouse RummaGEO Gene Perturbation Signatures -1.0 null Kidney TISSUES Experimental Tissue Protein Expression Evidence Scores 2025 1.0 1.946 GTEX-TSE9-3026-SM-3DB76 GTEx Tissue Sample Gene Expression Profiles 1.0 0.870225 ZNF143_H1-hESC_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null DOK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.858452 GTEX-PVOW-2626-SM-32PL8 GTEx Tissue Sample Gene Expression Profiles 1.0 1.07442 GSE242199_6_v_11_ntrk2_human RummaGEO Gene Perturbation Signatures 1.0 null sub-surface cisterna COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.514 GTEX-WWYW-0011-R10A-SM-3NB35 GTEx Tissue Sample Gene Expression Profiles 1.0 1.05809 Embryonic neural stem cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.201 kidney disease GWASdb SNP-Disease Associations 1.0 1.21019 GTEX-N7MS-0011-R1a-SM-2HMJG GTEx Tissue Sample Gene Expression Profiles 1.0 1.2576 GTEX-WZTO-0011-R1B-SM-3NMAR GTEx Tissue Sample Gene Expression Profiles 1.0 0.919052 cerebellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.255567 Hypoplastic Left Heart Syndrome DisGeNET Gene-Disease Associations 1.0 null