association	dataset	threshold value	standardized value
hsa-miR-3545-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Brain_CT2_CGE 283	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Midbrain central gray	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.636
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NDUFAF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51049
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0408
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950859
calcium-dependent phospholipid binding	GO Molecular Function Annotations 2015	1.0	null
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8307-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18926
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.94766
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Chronotype	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.95229
MCF7_Fedratinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168982
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.73524
H3K27me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF2-20460467-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-3926-01A-02R-1351-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.879084
T84	COSMIC Cell Line Gene CNV Profiles	1.0	2.06626
TGBC1TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
retroparafascicular area of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.998575
layer III of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.963614
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-182	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.3333
JUN-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-SJXC-0326-SM-2XCFI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.60848
SNU-C2B	COSMIC Cell Line Gene Mutation Profiles	1.0	null
secretion	GO Biological Process Annotations 2015	1.0	null
Rectum adenocarcinoma_READ_TCGA-AH-6643-11A-01R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_11_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72383
GTEX-WEY5-0826-SM-4LMIH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34017
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02227
mantle zone of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18859
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4FC-06A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Lenalidomide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148659
GTEX-WHSB-2026-SM-3LK6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43881
Acute Myeloid Leukemia_LAML_TCGA-AB-2884-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
parathyroid gland	HPA Tissue Protein Expression Profiles	1.0	1.26085
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.58
MCF7_SGI-1776 free base_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177567
CFTR_Deficiency_GDS1843_192_mouse_Lungs - Animals examined at 6 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-S32W-1326-SM-4AD5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.224
metal ion binding	GO Molecular Function Annotations 2025	1.0	null
lateral part of r6B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.30901
RCM1	DepMap CRISPR Gene Dependency	1.0	2.75132
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Navitoclax_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0225976
ZNF263_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.827855
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TP53INP2_KO_GDS5053_277_mouse_Skeletal muscle - SKM-KO	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K9me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_SUZ12_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Learning Disorders	CTD Gene-Disease Associations	1.0	1.19146
r3 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18626
EFM-192C	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01805
GTEX-P4QT-1726-SM-2S1NQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14525
AIM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33056
GTEX-TMMY-1626-SM-4DXTY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873757
GSE148695,GSE167284_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.0131
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
sudden cardiac death	GWASdb SNP-Phenotype Associations	1.0	2.08106
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Main olfactory bulb, granule layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.37345
Dorsomedial nucleus of the hypothalamus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06023
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r2 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01669
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828935
KIAA2013	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30724
JUN	ChEA Transcription Factor Targets	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.06211
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22266
Sarcoma_SARC_TCGA-X6-A7WB-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881468
spinalcordupper	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.04352
NCI-H2009	COSMIC Cell Line Gene CNV Profiles	1.0	2.06626
SULT2A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37059
Lung adenocarcinoma_LUAD_TCGA-NJ-A55O-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205163,GSE205164_2_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
r3 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2971
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
cellular component organization	GO Biological Process Annotations 2015	1.0	null
NPAS4 regulates expression of target genes	Reactome Pathways 2024	1.0	null
membrane part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
H3K9me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.1694
JUN-21703547-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCIH2087	CCLE Cell Line Gene CNV Profiles	1.0	2.85005
hsa-miR-4762-3p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5117-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-SNOS-1626-SM-3NMA4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04433
synaptic vesicle cycle	GO Biological Process Annotations 2023	1.0	null
SUZ12-18974828-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
UFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0368
red nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01537
Brain_CT2_Inh L1 SST DEFB108B	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.74
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SG in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.844508
DHX36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18105
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.22691
Main olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.43652
OlfactoryBulb	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.08918
TAF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Decitabine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141767
GSE164874_5_v_13_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF239	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03802
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7129-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10123531-NIHMS1874945-supplement-Table_S3.xlsx-SOX17_BCAT_cobound_coreg_peaks-Gene_Name_SOX17	Rummagene Transcription Factor Associations 2026	1.0	null
heart block	GWASdb SNP-Phenotype Associations	1.0	2.08106
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_JARID2_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00423
signal release from synapse	GO Biological Process Annotations 2025	1.0	null
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
periventricular stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.51045
Reflex, Abnormal	CTD Gene-Disease Associations	1.0	1.16269
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00195
hsa-miR-195	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
HCC60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57471
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.902225
advanced circadian behavior phase	MGI Mouse Phenotype Associations 2023	1.0	null
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
terminal paraventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20875
MCF7_Dasatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151022
GLIS3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0376
MCF7_PF-3845_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140778
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.767769
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.4404
KCNQ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07888
hsa-miR-519c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.23897
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862283
Visual Seizure	DisGeNET Gene-Disease Associations	1.0	null
FOXF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5067
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.945057
REEP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37553
MCF7_Sorafenib Tosylate_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137915
mRNA_MYCN_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Perturb_9041_KO_UTX/JMJD3_SRP158713	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.20836
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5243-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Dystrobrevin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.922
NUGC2	CCLE Cell Line Gene CNV Profiles	1.0	1.60635
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.281
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A119-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.426
RPLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06765
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPK-1726-SM-48TC4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.93671
OAW-28	COSMIC Cell Line Gene CNV Profiles	1.0	2.06626
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
synaptic vesicle exocytosis	GO Biological Process Annotations 2015	1.0	null
rostral putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04238
Accessory olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.682
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Recombination nodule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.564
GTEX-PX3G-1426-SM-48U1J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02305
HCC33	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.09
rostral paraventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67557
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861556
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.34954
intermediate stratum of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45029
GTEX-PSDG-0626-SM-2S1OE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40454
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08033
SIN3A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Calyx of Held	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.621
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PP-2526-SM-3P61P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11683
hsa-miR-4795-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
organelle membrane	GO Cellular Component Annotations 2015	1.0	null
GTEX-PWN1-1726-SM-2S1O9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44132
mediodorsal nucleus of thalamus_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3866
hsa-miR-448	TargetScan Predicted Conserved microRNA Targets	1.0	0.248923
NFE2L2	ChEA Transcription Factor Targets	1.0	null
HCC1954	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.15916
GSE158458_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF449	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.5681
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26759
arcuate nucleus of medulla, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.14078
GTEX-UJHI-1326-SM-4IHJO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0963
U343	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35712
496100418_TCx_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.83415
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.061012
Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-2692-11A-01R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83875
CALU-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08007
H3K27me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
layer 4 of FCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13858
MCF7_SRT3025 HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0155433
GSE175787_8_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Epothilone A_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148143
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA2-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Unnamed_13_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
periventricular stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41244
clathrin binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19908
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZSCAN30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1751
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.97727
AR	ChEA Transcription Factor Targets	1.0	null
GSE195559_6_v_5_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BICR31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41414
Parkinson's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.03979
E2F6	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7328-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.571619
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.207
Prostate adenocarcinoma_PRAD_TCGA-EJ-7783-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
obstructive lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.035343
H2BC12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08309
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2527
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
RPL36A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96495
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Plagl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8312
Main olfactory bulb, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.1752
NCI-H838	COSMIC Cell Line Gene CNV Profiles	1.0	2.06626
GTEX-NPJ7-1726-SM-2YUNA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20204
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.929303
KMS28BM	CCLE Cell Line Gene CNV Profiles	-1.0	-1.88981
PMC7914369-thnov11p3676s2.xls-BPTF-signature-geneId_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
FLNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27271
PAK4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81314
Primary somatosensory area, mouth, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03868
ATP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23321
arcuate nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17863
GTEX-XMK1-1026-SM-4B65H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02893
abnormal behavior	MPO Gene-Phenotype Associations	1.0	null
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE175787_4_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
Tetanus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.182
follicle-stimulating hormone complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.613
SP3_Deficiency_GDS3058_610_mouse_Embryonic heart  (day 12.5 C57Bl/6)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lacrimal gland acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.629
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055209
ZPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38051
embryoday6.5	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.38335
Pitt-Hopkins syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.392
hsa-miR-130b	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68869
r5 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17322
C2 domain	InterPro Predicted Protein Domain Annotations	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_TAK-901_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173715
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
epididymis	HPA Tissue Protein Expression Profiles	1.0	1.26085
GSE175787_8_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SSA3-0526-SM-32QPL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.28209
MCF7_MK-0752_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0190633
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-down-Gene_ID_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
Epilepsy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.268
GTEx Nerve 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	11.2926
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.999312
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Prednisone_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152421
Anterior olfactory nucleus, external part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58051
ventral posteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.80939
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.923324
hsa-miR-532-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Periglomerular cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.667
RKN	CCLE Cell Line Gene CNV Profiles	1.0	1.39795
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEIS1_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
r2 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04476
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.34371
Resting Heart Rate	DisGeNET Gene-Phenotype Associations	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A3HE-01A-21R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZR751	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.82264
Infralimbic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
Bed nuclei of the stria terminalis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09361
CL-34	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.905
r5 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78714
496100542_PCx_no dementia_no TBI_82_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.01378
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AKT1_knockout_211_GSE39699	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.61543
liver	HPA Tissue Protein Expression Profiles	-1.0	-1.22691
NCIH1373	DepMap CRISPR Gene Dependency	1.0	2.37895
Brain_CT2_Inh L1-2 VIP PTGER3	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
GTEX-TMMY-0526-SM-33HBC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05031
Acute Myeloid Leukemia_LAML_TCGA-AB-2910-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H-508	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.55
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35222
SRSF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12828
response to calcium ion	GO Biological Process Annotations 2023	1.0	null
hsa-miR-607	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r2 part of superior vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23153
H3K27me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-2526-SM-2S1PG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34889
MCF7_Ramelteon_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172337
MG-63	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterograde trans-synaptic signaling	GO Biological Process Annotations 2023	1.0	null
AR-27623747-22RV1-MOUSE-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
shares	GeneRIF Biological Term Annotations	1.0	null
coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
ELK1::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6891
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary somatosensory area, barrel field, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00537
medial part of r3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20019
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.848354
GTEX-XUW1-0626-SM-4BOP4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33136
hsa-miR-548n	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.292157
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	1.0	null
r7 part of the dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17626
GSE131649_6_v_5_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RFC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71087
posteroventral (inferior) parietal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19218
NMS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.321
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Down Syndrome_Fetus_GSE10758	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.33777
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.05163
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_15_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-629	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-QDT8-0326-SM-32PL1	GTEx Tissue Sample Gene Expression Profiles	1.0	2.17854
Chromaffin cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.633
HOXD12::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.6488
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Cerebral ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.606
MCF7_CEP-33779_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0189167
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-6846-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
snare binding	GO Molecular Function Annotations 2015	1.0	null
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08918
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE192870_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SKM1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69606
Anxiety Disorders	CTD Gene-Disease Associations	1.0	1.20097
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10437
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.90663
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.976505
MCF7_Busulfan_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139554
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02192
GSE234340_3_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of the myocardium	GWASdb SNP-Phenotype Associations	1.0	1.01636
mantle zone of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1855
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.16795
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.13808
JUND-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
outer CP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.21221
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-7289-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.08544
UTP14A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90313
HS944T	Achilles Cell Line Gene Essentiality Profiles	1.0	1.66426
GSE228106_0_v_4_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain_CT2_Inh L1-2 VIP PTGER3	HuBMAP ASCT+B Annotations	1.0	null
CORL311	DepMap CRISPR Gene Dependency	1.0	5.39091
EZH2_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBTPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4892
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81031
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of neurotransmitter levels	GO Biological Process Annotations 2015	1.0	null
signal release from synapse	GO Biological Process Annotations 2023	1.0	null
CP in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.2265
Roe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.714
Checkpoint clamp complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.665
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5UL-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
synaptic vesicle exocytosis	GO Biological Process Annotations 2025	1.0	null
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
MDAMB157	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.55365
LIM1215	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CALU-6	COSMIC Cell Line Gene CNV Profiles	1.0	2.06626
Secretory vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.988
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_136_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7465-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3ET-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC6137307-mmc2.xlsx-IRF9-IFNa-Table_S1_IRF9-IFNa_Related_to_Figure_1_IRF9	Rummagene Transcription Factor Associations 2026	1.0	null
putative	GeneRIF Biological Term Annotations	1.0	null
Renal coloboma syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.422
regulation of regulated secretory pathway	GO Biological Process Annotations 2023	1.0	null
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	167.56
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.061
PANC0504	DepMap CRISPR Gene Dependency	1.0	5.64528
reading	GeneRIF Biological Term Annotations	1.0	null
SCRT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.8929
H3K9me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Ivosidenib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.018111
GSE234340_12_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
TP53INP2_KO_GDS5053_544_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23697
JUN-21703547-K562-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.0475
OUMS-23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.717472
abnormal electrophysiology of sinoatrial node origin	GWASdb SNP-Phenotype Associations	1.0	2.08106
Heart rate variability traits (SDNN)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.45229
Lung squamous cell carcinoma_LUSC_TCGA-56-8082-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ6-1726-SM-2S1O6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3537
NCOR-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.12305
RNF2-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE165678_0_v_5_stat5a_human	RummaGEO Gene Perturbation Signatures	1.0	null
SMAD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33468
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43353
PMC9733061-13059_2022_2800_MOESM5_ESM.xlsx-Table_S4-Table_S4_Genes_assigned_to_JUNB_binding_sites_Each_peak_was_assigned_to_the_nearest_TSS_JUNB	Rummagene Transcription Factor Associations 2026	1.0	null
Urogenital Abnormalities	CTD Gene-Disease Associations	1.0	1.29011
Protein-protein interactions at synapses	Reactome Pathways 2024	1.0	null
GSE145915_0_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1347
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73P-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.926017
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0626-SM-2TF4G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18846
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66195
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30064
obstructive lung disease	GWASdb SNP-Disease Associations	1.0	0.555426
ChIP_H3K9me3_19884255_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
DPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94262
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF7_Zileuton_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0192407
GSE166004_3_v_2_pld1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMK1-1826-SM-4B66F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31114
periventricular stratum of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.17335
secretory vesicle	GO Cellular Component Annotations 2023	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950859
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF217-24962896-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
IRS1_KO_GDS1219_303_mouse_brown preadipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
15474998-tableS1c	GeneSigDB Published Gene Signatures	1.0	null
ChIP_EZH2_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MCF7_Epothilone A_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148823
YAPC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29311
hsa-miR-4770	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
hsa-miR-15b	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Cerdulatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157604
MCC26	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KM-H2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02816
HNT34	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.27832
preopto-hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39469
calcium ion binding	GO Molecular Function Annotations 2025	1.0	null
bonemarrow	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.20422
T-T	COSMIC Cell Line Gene CNV Profiles	1.0	2.06626
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Gene expression (Transcription)	Reactome Pathways 2024	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.43046
MCF7_MK-0752_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151887
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.06836
SKMEL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53572
Mesothelioma_MESO_TCGA-LK-A4O2-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBP-20019798-JUKART-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Heart rate response to recovery post exercise (20 sec)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	5.75229
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	2.36337
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.594853
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.25588
MDAMB157	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97593
Perturb_2288_KD_XPO6_SRP245599	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10214
Parataenial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43189
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.551
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
PANC0327	Achilles Cell Line Gene Essentiality Profiles	1.0	1.19297
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RWS6-2426-SM-2XCB9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69628
Triangular nucleus of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34271
subthalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.76692
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12534504-41598_2025_20489_MOESM1_ESM.pdf-444-FOXA1_FOXA1	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_CNOT3_19339689	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Heart rate	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.32218
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	157.592
NUTM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75395
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.826819
TMEM200C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1343
AHR	ChEA Transcription Factor Targets	1.0	null
MCF7_Momelotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0233539
Electrocardiogram morphology (amplitude at temporal datapoints)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.952288
19168792-TableS3	GeneSigDB Published Gene Signatures	1.0	null
Neuroendocrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.571
A549	Achilles Cell Line Gene Essentiality Profiles	1.0	2.78491
LMSU	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05516
SMAD4	ChEA Transcription Factor Targets	1.0	null
GSE117212,GSE117214_0_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51504
MCF7_Azacitidine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138977
PMC7181746-41467_2020_15886_MOESM8_ESM.xlsx-Patient_15_CCF-Affected_Genes_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.1814
hsa-miR-301a	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
atrial fibrillation	GWASdb SNP-Phenotype Associations	1.0	2.08106
vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.336241
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91242
Synaptotagmin-10	InterPro Predicted Protein Domain Annotations	1.0	null
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.86501
Dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21731
MCF7_Motesanib Diphosphate_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0127682
SW900	COSMIC Cell Line Gene CNV Profiles	1.0	2.06626
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.700262
membrane	GO Cellular Component Annotations 2015	1.0	null
FOXH1-21741376-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Heart conduction disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.379
GTEX-WYVS-2426-SM-3NMA9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48145
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61459
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OIZI-0426-SM-2XCEF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38345
Olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.747
cation binding	GO Molecular Function Annotations 2015	1.0	null
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	220.169
Colo-678 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.889
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Entinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146755
GSE95077_1_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF75D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.8051
GARP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.735
Corpus albicans	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.931
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64674
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46996
medial subdivision of central nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44034
Throat	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07027
Olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.756
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950859
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3443-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145323,GSE145324_1_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49464
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831318
HDAC1	ENCODE Transcription Factor Targets	1.0	null
CTBP2-25329375-LNCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_UNC1999_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0277969
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-UY-A78O-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3923-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12347
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A4IH-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Autosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.241
MCF7_AG-490_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140747
Hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.512
HPAF-II	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.18753
NR1I2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05114
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218727_2_v_1_zkscan3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE106130_0_v_1_grhl2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF574	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.6841
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917015
Medial mammillary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.39
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_UNC1999_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0205283
RERFLCAD1	DepMap CRISPR Gene Dependency	1.0	3.55025
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.951557
GTEX-RUSQ-1826-SM-2TF6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32564
ZNF217	ChEA Transcription Factor Targets	1.0	null
GTEX-T6MN-0326-SM-32PMK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.12744
Lateral mammillary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-US-A776-01A-13R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Calcium	HMDB Metabolites of Enzymes	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MEIS2_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EBC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.826653
MCF7_Rucaparib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0159379
GATA2	ChEA Transcription Factor Targets	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
lower respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.035343
K562_Alvespimycin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147035
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
preoptic alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09906
respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.035343
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
establishment of vesicle localization	GO Biological Process Annotations 2015	1.0	null
GTEX-WZTO-1026-SM-3NM9P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54311
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.17665
GTEX-NPJ8-1326-SM-3LK6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48106
RERFLCAD1	CCLE Cell Line Gene CNV Profiles	1.0	1.78253
synaptic vesicle membrane	GO Cellular Component Annotations 2015	1.0	null
RUNX2-22187159-PCA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-24	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839154
midline nuclear complex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.912864
respiratory system disease	GWASdb SNP-Disease Associations	1.0	0.36021
CCDC59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83665
Dense core granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.18
hsa-miR-1297	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-SYMBOL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-2861	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-RTLS-0326-SM-2TF6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96809
Ciliated epithelial cell_Esophagus_Human	CellMarker Gene-Cell Type Associations	1.0	null
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3666	TargetScan Predicted Conserved microRNA Targets	1.0	0.219115
Perturb_8943_Mut_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14243
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.938868
NFKB1-27076634-BEAS2B-HUMAN-LUNG-INFLAMMATION	ChEA Transcription Factor Targets 2022	1.0	null
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.94797
UBTF	ENCODE Transcription Factor Targets	1.0	null
abnormal circadian period	MPO Gene-Phenotype Associations	1.0	null
H3K27me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.012
Primary dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.69
functional respiratory abnormality	GWASdb SNP-Phenotype Associations	1.0	0.849104
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_EA_PCa-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCAD_KO_GDS4546_422_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H3K27me3_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-58-8390-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WM35	COSMIC Cell Line Gene Mutation Profiles	1.0	null
INTS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05295
Disease of metabolism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.021
L363	Achilles Cell Line Gene Essentiality Profiles	-1.0	-3.22921
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01517
hsa-miR-548d-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
ZBTB33	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5234
Paraventricular hypothalamic nucleus, parvicellular division, anterior parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14634
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30646
encoding	GeneRIF Biological Term Annotations	1.0	null
r3 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40688
GTEX-WY7C-2626-SM-3NB2P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51518
NCI-H2087	COSMIC Cell Line Gene CNV Profiles	1.0	2.06626
GTEX-PWOO-0426-SM-48TZF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859719
hsa-miR-519b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
TATDN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82257
posterior (ventral) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00406
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
medial part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.56662
MCF7_Resminostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136569
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4049
BON-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.355
intermediate stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32557
GTEX-TSE9-0326-SM-3DB82	GTEx Tissue Sample Gene Expression Profiles	1.0	2.20646
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TMEM60	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10245
CL-40	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.85385
496100326_TCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.07669
Mesothelioma_MESO_TCGA-LK-A4O5-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CNOT3-19339689-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
binding	GO Molecular Function Annotations 2015	1.0	null
advanced circadian phase	MPO Gene-Phenotype Associations	1.0	null
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Mitochondrial metabolism disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.045
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01232
Hnf1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3739
HT1376	CCLE Cell Line Gene CNV Profiles	-1.0	-2.73774
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V955-1726-SM-4JBHF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824027
Expressive language disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.03
lateral trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44762
Mesothelioma_MESO_TCGA-TS-A7P0-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MM426	DepMap CRISPR Gene Dependency	1.0	2.82373
Lung squamous cell carcinoma_LUSC_TCGA-O2-A5IB-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
basal ganglia disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.369628
GTEX-W5X1-2826-SM-3GILM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58051
cytoplasmic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.258745
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-26a	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
MCF7_ZM 447439_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128507
MCF7_Cyclocytidine HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0176652
hsa-miR-4436b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
MCF7_CYC116_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0215242
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03534
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.52509
CRO-AP2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
Gli1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.4259
Parasympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.833
GTEX-RU1J-1326-SM-46MUL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899583
synapse	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
mRNA_DPPA5A_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
stomach_3a	HPA Tissue Sample Gene Expression Profiles	1.0	0.890852
POU5F1-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
K562_PD173074_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0206662
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R3-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00471
CHD1	ENCODE Transcription Factor Targets	1.0	null
SUZ12-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SNCA_KO_GDS4153_443_mouse_Striatum - 6 months	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
prostate	HPA Tissue Protein Expression Profiles	1.0	1.26085
Perturb_4427_KO_Eed_SRP172483	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.07304
20140255-TableS1	GeneSigDB Published Gene Signatures	1.0	null
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.689226
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-2681	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
Prostatic Diseases	CTD Gene-Disease Associations	1.0	1.08762
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836407
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936896
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COV362	Achilles Cell Line Gene Essentiality Profiles	1.0	1.2506
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Status epilepticus	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.158
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16955
GSE157960_0_v_3_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57571
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.882122
hsa-miR-519a	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H2087	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XMD1-0526-SM-4AT4Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50077
AP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
DorsalRootGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.18781
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.61285
PMC4774101-13024_2016_87_MOESM3_ESM.xlsx-Table_S9-COMMON_DEGs_IN_AT_LEAST_3_OUT_OF_4_CONDITIONS_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
suprachiasmatic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.494136
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Crizotinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0158341
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14634
GSE234340_9_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Neck	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Lung squamous cell carcinoma_LUSC_TCGA-39-5022-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.867563
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.063582
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.936896
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7389-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ebolavirus(EBOV)_1day_Splenocytes_19683682_GSE17509	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.84867
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.03974
hsa-miR-548z	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
septohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25373
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
neurotransmitter secretion	GO Biological Process Annotations 2015	1.0	null
RPAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27977
single-organism transport	GO Biological Process Annotations 2015	1.0	null
H3K27me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MERO48A	DepMap CRISPR Gene Dependency	1.0	2.67119
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00696
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE65617_2_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ1-1326-SM-4DXU7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29713
chemical synaptic transmission	GO Biological Process Annotations 2023	1.0	null
PDE10A_KO_GDS4542_291_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847446
NOMO1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.28438
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Resting heart rate	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.31549
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.1171
Bed nuclei of the stria terminalis, posterior division, transverse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07352
Pontine gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50903
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-P4PQ-1726-SM-3NB15	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980695
Kidney Chromophobe_KICH_TCGA-KN-8419-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of catecholamine secretion	GO Biological Process Annotations 2023	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
PPARD_KO_GSE16048_54_mouse_pancreas (islets, PDX1-expressing cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882358
MCF7_Ivosidenib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0188703
GSE131649_2_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSG-2726-SM-4KKZJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966945
Kidney Chromophobe_KICH_TCGA-KL-8343-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
18394172-S4GeneList	GeneSigDB Published Gene Signatures	1.0	null
MCF7_Crizotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0200403
Liver Diseases	CTD Gene-Disease Associations	1.0	1.12117
autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.056265
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.834212
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LD-01A-12R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102505_6_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BB30HNC	DepMap CRISPR Gene Dependency	1.0	2.40922
GSE128076_1_v_3_doxycycline_human	RummaGEO Drug Perturbation Signatures	1.0	null
mantle zone of r7Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74141
anterior nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.941893
SNU-81	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7745-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain - Hypothalamus	GTEx Tissue Gene Expression Profiles 2023	1.0	2.68522
Glomerular layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.581
Olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.757
UACC-62	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.990669
GSE180185_9_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
nerve	GTEx Tissue Gene Expression Profiles	1.0	1.1468
HOP62	CCLE Cell Line Gene CNV Profiles	1.0	1.41498
GSE166944_0_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
OAW28	CCLE Cell Line Gene CNV Profiles	1.0	1.54914
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30953
hsa-miR-301b	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.033
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.861556
hsa-miR-892a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
bed nucleus of stria terminalis	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00113
KMT5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.68155
HSPA9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71296
H3K27me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Accessory olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63827
POLR1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81553
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28475
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.46065
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054715
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Trichostatin A_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0107907
intermediate stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03684
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XQ8I-0726-SM-4BOPU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14475
MCF7_Clevudine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145309
Lake et al.Science.Ex8_Brain_Human	CellMarker Gene-Cell Type Associations	1.0	null
GATA1-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	123.058
HCFC1	ENCODE Transcription Factor Targets	1.0	null
medial ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.841724
Generic Transcription Pathway	Reactome Pathways 2024	1.0	null
mantle zone of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.207
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23022
GTF2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27939
PMC11801220-NIHMS2038999-supplement-16.xlsx-Exc-PBX3-gene_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
Brain_CT2_Inh L1 SST DEFB108B	HuBMAP ASCT+B Annotations	1.0	null
GSE140997_4_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
TNFRSF11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87197
MCF7_Cyclocytidine HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145471
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RXR-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
hsa-miR-4666-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22611
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.868772
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A6DV-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Olfactory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28855
Chromaffin granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.246
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
anterograde trans-synaptic signaling	GO Biological Process Annotations 2025	1.0	null
TFDP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.7564
r2 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17701
abnormal circadian phase	MPO Gene-Phenotype Associations	1.0	null
NOMO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09318
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25263
GSE182921_0_v_1_slit2_human	RummaGEO Gene Perturbation Signatures	1.0	null
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.3714
MCF7_Aminoglutethimide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142184
GSE84148,GSE96938_0_v_2_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TE-12	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4477a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25968
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.076269
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5461-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNA Polymerase II Transcription	Reactome Pathways 2024	1.0	null
MCF7_SRT1720 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174886
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22728
Atrial fibrillation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.241
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Anterior cingulate area, dorsal part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09408
calcium-dependent phospholipid binding	GO Molecular Function Annotations 2025	1.0	null
MCF7_Valproic acid sodium salt_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139893
SNU685	CCLE Cell Line Gene CNV Profiles	1.0	1.54627
NZOV9	DepMap CRISPR Gene Dependency	1.0	3.70195
BACH1	ENCODE Transcription Factor Targets	1.0	null
MCC13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_cerebellum_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGFR_druginhibition_83_GSE27640	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.3786
GSE118816_2_v_3_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DMS-53	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CGTH-W-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCF7_Costunolide_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0140556
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H322M	COSMIC Cell Line Gene CNV Profiles	1.0	2.06626
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.631931
hsa-miR-17	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE207582_2_v_1_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Mitochondrial complex I deficiency	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.678
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.99997
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906989
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3328-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_MK-0752_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149134
medial portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.835468
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
layer 5 of PCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04336
synapse part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.070759
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983654
GTEX-RU72-1126-SM-2TF6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31175
CW-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5783-01A-41R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ER_ZNF_GATA3-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
TTK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58584
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-0.868329
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Colorectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ZNF263	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.2542
GSE119978,GSE180930_0_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE157383_3_v_2_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
identical protein binding	GO Molecular Function Annotations 2015	1.0	null
WM-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFYB	ENCODE Transcription Factor Targets	1.0	null
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44165
GTEX-QXCU-0126-SM-2TC5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.43215
rhombomere 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23546
PMC5263239-mmc2.xls-THP-1_-_MLL-AF9-Non-spreading_targets_gene_names_1900_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131649_2_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RR interval (heart rate)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.822185
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE224131_5_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF708	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0212
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5981
PMC11801220-NIHMS2038999-supplement-15.xlsx-Inh-MEF2C-gene_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EL-11A-11R-A155-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2143
MCF7_Veliparib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0183813
GSE234514,GSE234516_2_v_0_mitf_human	RummaGEO Gene Perturbation Signatures	1.0	null
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4049
GTEX-UPJH-0626-SM-4IHJN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74305
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QESD-1726-SM-2S1R7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18865
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.899244
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4676-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K9me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.04509
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YAPC	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43194
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.824649
Perturb_3041_KO_Pgr_ERP140354	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Presynaptic cytosol	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.699
RNF2	ChEA Transcription Factor Targets	1.0	null
HT-115	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Brain_CT2_MGE 240	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.875424
PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
sick sinus syndrome	GWASdb SNP-Phenotype Associations	1.0	2.08106
GSE78199_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WHSC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Medial preoptic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0024
disease	GWASdb SNP-Disease Associations	1.0	0.049715
vesicle fusion	GO Biological Process Annotations 2015	1.0	null
PMC3348545-NIHMS263168-supplement-3.pdf-295-SOX5_SOX5	Rummagene Transcription Factor Associations 2026	1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13909
HDAC6	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-153	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
superficial stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44849
GTEX-XAJ8-0726-SM-47JY5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869455
posterior (caudal) superior temporal cortex (area 22c)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42505
Pallidum, caudal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09396
ECSCR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59844
EFM-192A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2449
HBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22134
GTEX-VJYA-1726-SM-3NMDQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65698
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
CBX3	ENCODE Transcription Factor Targets	1.0	null
GSE225656_2_v_1_tsc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
NCI-H727	COSMIC Cell Line Gene CNV Profiles	1.0	2.06626
RBIS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12381
GTEX-P4PP-1726-SM-2S1NS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840022
neurotransmitter transport	GO Biological Process Annotations 2015	1.0	null
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26119
K562_KW-2449_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0120198
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA6_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
HCC70	DepMap CRISPR Gene Dependency	1.0	2.17939
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MI-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Alisertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.011427
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.915511
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.35723
PMC10679653-mmc2.xlsx-ISL1_KO_Markers_L-Unnamed_0_ISL1	Rummagene Transcription Factor Associations 2026	1.0	null
prostate	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.953941
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE159728,GSE159730_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
arrhythmia	GWASdb SNP-Phenotype Associations	1.0	1.54299
TRIP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60481
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
positive regulation of calcium ion-dependent exocytosis	GO Biological Process Annotations 2023	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11161485-41531_2024_729_MOESM1_ESM.pdf-9-ENSG00000176222_ZNF404	Rummagene Transcription Factor Associations 2026	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.882757
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-IF-A4AK-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X5EB-2526-SM-4E3HY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45723
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
lung	HPA Tissue Protein Expression Profiles	-1.0	-1.22691
PRR15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43778
PPM1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36129
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.41217
Lung adenocarcinoma_LUAD_TCGA-91-6835-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NKX2-6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09811
PPP2R5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03589
HCC1569	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-T5JC-1226-SM-4DM7C	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87374
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.67614
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.826634
GTEX-SUCS-1726-SM-32PM8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969744
nucleus of the stria medullaris (prethalamic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16761
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.035343
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rhombomere 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22917
PMC10247733-41408_2023_863_MOESM4_ESM.pdf-574-ZSCAN1_ZSCAN1	Rummagene Transcription Factor Associations 2026	1.0	null
anion binding	GO Molecular Function Annotations 2015	1.0	null
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.537416
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.879695
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Roxadustat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177065
Acute Myeloid Leukemia_LAML_TCGA-AB-2873-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4775	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
Rectum adenocarcinoma_READ_TCGA-AG-3731-11A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-8499-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228106_0_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OXRP-2526-SM-2S1NO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47175
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
core of P-DMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18735
cardiomyopathy	GWASdb SNP-Phenotype Associations	1.0	1.22293
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10505
mantle zone of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38666
GTEX-T8EM-1526-SM-3DB7I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24242
GSE164529_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MEIS1-26253404-OPTIC-CUPS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884556
GTEX-XPVG-2026-SM-4B65E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.913973
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55891
Nucleus accumbens	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.185
PMC10123531-NIHMS1874945-supplement-Table_S6.xlsx-SOX2_BCAT_cobound_peaks-Gene_Name_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_INO-1001_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0230378
mammalian phenotype	MPO Gene-Phenotype Associations	1.0	null
Transport vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE199606_5_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Ayme-Gripp syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.129
olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.923339
GSE131798,GSE131804_5_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Ventral posteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.68251
RCOR1	ENCODE Transcription Factor Targets	1.0	null
A-VN-1203-2004(H5N1)_Day2-10^4pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.73587
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.84139
NCI-H727	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.02973
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1265
TT	CCLE Cell Line Gene CNV Profiles	1.0	1.85687
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0626-SM-2XCF6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98194
Zic3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.5519
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.853062
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28133
SNU182	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34948
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ITGA7_OE_GDS3209_142_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.898146
hsa-miR-1302	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NTERA2CLD1	DepMap CRISPR Gene Dependency	1.0	2.15412
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08538
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.046245
NOCT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9297
external segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.867032
KYO1	CCLE Cell Line Gene CNV Profiles	1.0	1.91207
NB13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.0041
synapse part	GO Cellular Component Annotations 2015	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17X-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
Vesicle lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.143
MCF7_GSK1070916_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0261053
integral component of membrane	GO Cellular Component Annotations 2015	1.0	null
Brn3a_KO_GDS1651_247_mouse_Embryonic (day 13.5) trigeminal ganglia - heterozygous	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PPARD-21283829-MYOFIBROBLAST-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC10330983-ab-22-0432-Supplementary-Table-8.pdf-97-SOX5_SOX5	Rummagene Transcription Factor Associations 2026	1.0	null
GSE175787_8_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
huntington's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.66914
GTEX-WRHU-0626-SM-3MJFI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.92022
PMC8755441-mmc3.xlsx-IRF7-Up-SUZ12_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
OB outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.06857
GSE175787_13_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.893138
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
pontine hindbrain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15275
lower respiratory tract disease	GWASdb SNP-Disease Associations	1.0	0.384023
preoptic area	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.324605
GTEX-WFON-1526-SM-4LVMP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00605
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.36905
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.153
CREB1	ENCODE Transcription Factor Targets	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19966
establishment of localization	GO Biological Process Annotations 2015	1.0	null
TTLL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11476
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterior hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.215
H3K27me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.057204
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.830236
LNCAP-CLONE-FGC	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Heart rate	GWAS Catalog SNP-Phenotype Associations	1.0	1.15051
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	168.762
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5040-01A-21R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
Artery - Tibial	GTEx Tissue Gene Expression Profiles 2023	1.0	5.43038
GLIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.3769
prethalamic eminence	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16727
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06626
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14885
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73517
hsa-miR-409-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuron_Retina_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29N-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
kidney_a	HPA Tissue Sample Gene Expression Profiles	1.0	0.9344
COLO-679	COSMIC Cell Line Gene Mutation Profiles	1.0	null
abnormality of cardiac morphology	GWASdb SNP-Phenotype Associations	1.0	0.3833
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100364_TCx_possible Alzheimer's disease_TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.03131
adiposetissue	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.37683
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG4-1126-SM-2S1P7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28536
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10763
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39863
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10259
GSE245270_1_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular response to salt	GO Biological Process Annotations 2023	1.0	null
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24814
hsa-miR-548c-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
preoptic region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.62395
synaptic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
MYC-27129775-CHIP-SEQ-CORNEA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_Decitabine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154915
SUZ12-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-103a	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
hsa-miR-3074-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
Posterior hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.598
Heart rate response to recovery post exercise (10 sec)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	6.5301
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nasopharynx	HPA Tissue Protein Expression Profiles	-1.0	-1.22691
Facial motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15122
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.868467
spleen	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.928866
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174735_4_v_0_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7669-01A-21R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Anterior olfactory nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.869
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06995
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862283
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.282558
MCF7_Streptozotocin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163743
hsa-miR-3133	TargetScan Predicted Conserved microRNA Targets	1.0	0.568687
H3K27me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HHEX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24977
MDAMB175VII	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.03495
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Ensembl_ID_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.00453
Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2918-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
granular layer of caudal dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.906875
hsa-miR-4666-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
intermediate stratum of PThE	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16727
HCC1954	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.726476
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
GTEX-POMQ-2026-SM-2S1OD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48876
GSE234340_4_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.922321
GTEX-XPT6-2126-SM-4B66P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994691
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	1.53462
HCC1954	CCLE Cell Line Gene CNV Profiles	-1.0	-2.24105
NCIH322	CCLE Cell Line Gene CNV Profiles	1.0	1.66202
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80K-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00296
GSE148269,GSE148273_0_v_1_arid4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
hsa-miR-4759	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SARNP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3415
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A770-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of calcium ion-dependent exocytosis	GO Biological Process Annotations 2025	1.0	null
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862283
Intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.879411
GTEX-XLM4-0011-R8A-SM-4AT44	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862673
CALU6	CCLE Cell Line Gene CNV Profiles	1.0	1.45457
Heart rate variability traits (pvRSA/HF)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.3699
fallopiantube_8c	HPA Tissue Sample Gene Expression Profiles	1.0	2.05166
calcium-ion regulated exocytosis	GO Biological Process Annotations 2023	1.0	null
cell junction	GO Cellular Component Annotations 2015	1.0	null
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart rate response to exercise	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.0699
body of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.70356
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE74251_0_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mucous acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.654
ZSCAN21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.0507
JEKO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57328
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
behavior/neurological phenotype	MPO Gene-Phenotype Associations	1.0	null
NCIH2887	DepMap CRISPR Gene Dependency	1.0	11.9171
CDC27	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72591
MCF7_FLLL32_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147299
Human - Motor Cortex - Cluster - PVALB+ CDK20+ Layer 1-2 GABAergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
preoptic region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.69728
GTEX-RNOR-1326-SM-48FDE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89418
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.882273
MCF7_Resveratrol_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0194753
COLO 699	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34861
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.893331
posteroventral (inferior) parietal cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19067
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTCF	ENCODE Transcription Factor Targets	1.0	null
JARID2	ChEA Transcription Factor Targets	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.72905
Histaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.613
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0495
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08394
ITSN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53646
PMC12821819-40478_2025_2173_MOESM9_ESM.xlsx-Supplementary_Table_3a-Supplementary_Table_3A_List_of_Top_1000_Genes_with_the_Highest_Stochasticity_by_JSD_in_the_ATRT-MYC_Subtype_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
establishment of localization in cell	GO Biological Process Annotations 2015	1.0	null
ChIP_K27me3_17603471_mouseMEF	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
superficial stratum of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29206
H3K9me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.416896
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.97136
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
OCT4-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
LS-411N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
calcium ion binding	GO Molecular Function Annotations 2023	1.0	null
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SE5C-1326-SM-4BRUH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13445
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01778
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2A2-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04333
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8835_KO_RING1A_SRP345831	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AMO-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04938
FBN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66512
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.46944
Puberty, Precocious	CTD Gene-Disease Associations	1.0	1.25899
mantle zone of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.31067
LRSAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14373
MCF7_Belinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0102669
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09884
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.839439
FOXO1_KD_GDS2720_478_mouse_LSK	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FOXB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15449
preoptic	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.58033
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.210925
KMS-28BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.61526
CNOT3	ChEA Transcription Factor Targets	1.0	null
intermediate part of r3B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08708
regulation of localization	GO Biological Process Annotations 2015	1.0	null
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77487
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.83212
MCF7_Motesanib Diphosphate_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0122364
GTEX-QLQW-1426-SM-2S1QU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54289
Substantia nigra, reticular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44762
Perturb_2418_OE_PDE5_ERP011301	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3314
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54605
TMEM214	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8642
MAX	ENCODE Transcription Factor Targets	1.0	null
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.376643
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.262755
phospholipid binding	GO Molecular Function Annotations 2015	1.0	null
Heart rate response to recovery post exercise (50 sec)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	5.30969
Epidermolysis bullosa dystrophica	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
adrenalgland	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.23077
GSE80098,GSE80366_0_v_8_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.219
Nucleus preopticus medialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.957
GSE149264,GSE149267_4_v_3_trp53_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
E2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.3564
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39W-11A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
contains	GeneRIF Biological Term Annotations	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.839255
GTEX-R53T-1226-SM-48FCT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.906241
hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.164502
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GTEX-Q2AH-1926-SM-2S1PN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65676
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
WHSC1	ENCODE Transcription Factor Targets	1.0	null
MCF7_KW-2449_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0384542
p1 part of the substantia nigra reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30865
syntaxin binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-W5WG-2326-SM-3GIJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15837
second (ventral) preoptic domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31569
Right atrium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.215
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.993476
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24391
Brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.246
amygdaloid complex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.41601
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4512	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
Piriform area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.23
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WM2664	CCLE Cell Line Gene CNV Profiles	-1.0	-1.35194
periventricular stratum of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.65936
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SNU1105	Achilles Cell Line Gene Essentiality Profiles	1.0	1.0671
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL2L10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25601
MCF7_AZD1480_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.012413
PMC7592539-12885_2020_7456_MOESM4_ESM.xlsx-Sup_TableS3_LMS_del_genes_conf-12q13_11_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0287
Bed nuclei of the stria terminalis, posterior division, principal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09073
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Lamellar body membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.949
Lateral terminal nucleus of the accessory optic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70003
H3K27me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r7 part of cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.74361
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63911
dorsal tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03684
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46655
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
SOX2-21211035-LN229_GBM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BD-A3EP-11A-12R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-424	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
sw1463	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.517
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Midline group of the dorsal thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05772
intrinsic component of membrane	GO Cellular Component Annotations 2015	1.0	null
chr12_33208001_G_A_b38	GTEx eQTL 2025	1.0	1.9005
CORL105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62122
VCAP	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.08473
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of exocytosis	GO Biological Process Annotations 2015	1.0	null
layer 1 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18383
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91425
GSE90821_3_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XUZC-1526-SM-4BRV4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.999476
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62173
medial habenular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26006
SLC9A3_KO_GDS3323_495_mouse_colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9019
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
RP1_KO_GDS1845_190_mouse_Retinas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX4_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
shortened circadian period	MPO Gene-Phenotype Associations	1.0	null
GTEX-O5YW-1426-SM-3MJHF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946937
r2 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29041
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.884556
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.558457
hsa-miR-16	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
SH10TC	CCLE Cell Line Gene CNV Profiles	1.0	2.21581
synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.139002
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36668
superficial stratum of r6Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3306
MCF7_Disulfiram_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138698
GTEX-PW2O-1226-SM-48TCH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98989
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5153-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HDAC6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6870463-Table_7.xlsx-Family_H_No_LPS-Untreated_BMDMs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)HAAvirmut_7day-MOI-10^4_None_GSE37572	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.72141
Tertiary granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.638
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.00086
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-130a	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02128
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996243
Perturb_9527_KO_P2ry1_SRP342865	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	17.5467
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.998299
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053421
Bed nuclei of the stria terminalis, anterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12095
Prostate adenocarcinoma_PRAD_TCGA-EJ-7792-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_G007-LK_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0175351
CTBP2	ENCODE Transcription Factor Targets	1.0	null
VPS37B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76956
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12795
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099593
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
peduncular part of dorsomedial hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03541
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MCF7_A-366_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0105618
positive regulation of regulated secretory pathway	GO Biological Process Annotations 2023	1.0	null
MCF7_SNS-314 Mesylate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171472
NCIH69	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47167
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A1Q0-01A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MCF7_PJ34_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0194078
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neurexins and neuroligins	Reactome Pathways 2024	1.0	null
GSE205163,GSE205164_5_v_8_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSK3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26765
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.40111
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20323
HCC95	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93941
hsa-miR-553	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
RAD21	ENCODE Transcription Factor Targets	1.0	null
SARC9371	COSMIC Cell Line Gene Mutation Profiles	1.0	null
fallopiantube_5a	HPA Tissue Sample Gene Expression Profiles	1.0	1.10331
RNF2	ENCODE Transcription Factor Targets	1.0	null
GTEX-XOTO-0326-SM-4B66K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.68662
HCC33	CCLE Cell Line Gene CNV Profiles	1.0	1.51257
Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	46.1722
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JARID2-20064375-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MCF7_MC1568_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0253336
GTEX-TKQ2-1326-SM-4DXT9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841619
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-SALL4_unique_peaks-Unnamed_14_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
RPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85321
PATU8902	CCLE Cell Line Gene CNV Profiles	1.0	1.67808
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2146
hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.298524
Lung squamous cell carcinoma_LUSC_TCGA-18-4721-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2087	DepMap CRISPR Gene Dependency	1.0	2.02696
lateral reticular nucleus (principal part)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06754
hsa-miR-361-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05242
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.81078
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31907
Lake et al.Science.Ex2_Brain_Human	CellMarker Gene-Cell Type Associations	1.0	null
OVK-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
respectively	GeneRIF Biological Term Annotations	1.0	null
GSE121809_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.256
EP300	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-548ac	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
SETDB1	ENCODE Transcription Factor Targets	1.0	null
K562_SRT2104_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0202454
SG in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.01105
ZNF287	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03161
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SKRC20	DepMap CRISPR Gene Dependency	1.0	3.13421
MCF7	DepMap CRISPR Gene Dependency	1.0	2.85715
MCEE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.41933
CAL78	CCLE Cell Line Gene CNV Profiles	1.0	1.4344
MTF2	ChEA Transcription Factor Targets	1.0	null
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Serous acinar cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.508
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
regulation of calcium ion-dependent exocytosis	GO Biological Process Annotations 2015	1.0	null
r4 part of pontine raphe cell population	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10759
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11705
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.28133
MCF7_Alisertib_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156261
HIKESHI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02023
FOXA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70033
CD34+	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.94626
MCF7_Enzastaurin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0101467
GTEX-XAJ8-1126-SM-47JYA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49362
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.925733
Lef1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.3478
dorsolateral prefrontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.08938
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875786
GSE239784_1_v_0_sat1_human	RummaGEO Gene Perturbation Signatures	1.0	null
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01962
GTEX-OXRN-1426-SM-3LK5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.61417
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BSX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06446
M14	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCF7_Ki8751_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.019014
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052499
MCF7_SB431542_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0162913
medial part of r4B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18782
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.15977
r2 part of principal trigeminal sensory nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38666
Lung adenocarcinoma_LUAD_TCGA-05-4250-01A-01R-1107-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16407
GTEX-T6MO-2026-SM-33HB4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09712
TCCSUP	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3ML-06A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
sensory perception of smell	GO Biological Process Annotations 2023	1.0	null
NXF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28647
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26037
Lung squamous cell carcinoma_LUSC_TCGA-43-A475-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10256
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970696
GTEX-WFON-1326-SM-4LVMN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14251
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
RERFGC1B	DepMap CRISPR Gene Dependency	1.0	2.98122
chronic obstructive pulmonary disease	GWASdb SNP-Disease Associations	1.0	0.963873
PMC8500868-401_2021_2354_MOESM5_ESM.xlsx-GEP_PATZ1-Gene_Symbol_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
Secretory vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
ChIP_SUZ12_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Sinoatrial node disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905562
periventricular stratum of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78714
superficial stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77872
GEMIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7697
GTEX-XXEK-2526-SM-4BRUR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43924
disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.035343
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.06044
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
PMC9160255-41467_2022_30710_MOESM4_ESM.xlsx-AR_specific_regulated_genes-ENSEMBL_AR	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-106a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Mitral cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.728
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXI3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31793
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12	ENCODE Transcription Factor Targets	1.0	null
mantle zone of r3BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0864
p3 portion of the substantia nigra pars reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47774
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SW 900	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.06587
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24727
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2809
EGR1	ENCODE Transcription Factor Targets	1.0	null
p2 portion of the substantia nigra pars reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48722
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29901
Venom gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.857
ARNT-22903824-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
single-organism localization	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906989
regulation of calcium ion-dependent exocytosis	GO Biological Process Annotations 2025	1.0	null
mRNA_NR5A2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
preoptic telencephalon	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10405
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	1.26085
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.924317
hsa-miR-3682-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.9018
CL-11	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05137
shortened circadian behavior period	MGI Mouse Phenotype Associations 2023	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.8292
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3599
SW1271	COSMIC Cell Line Gene CNV Profiles	1.0	2.06626
biological regulation	GO Biological Process Annotations 2015	1.0	null
secretion by cell	GO Biological Process Annotations 2015	1.0	null
NCIH727	CCLE Cell Line Gene CNV Profiles	1.0	1.37468
Lymphoma_burkitts(Raji)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.53279
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RL-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A11A-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.33769
ChIP_RNF2_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LRIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09089
Atrioventricular node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.015
GSE154577_6_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Olfactory glomerulus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.303
SUZ12-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of regulated secretory pathway	GO Biological Process Annotations 2025	1.0	null
exocytic vesicle	GO Cellular Component Annotations 2025	1.0	null
HDL cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
GTEX-XYKS-2526-SM-4BOPX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.912007
Lung squamous cell carcinoma_LUSC_TCGA-21-1080-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.872431
organelle fusion	GO Biological Process Annotations 2015	1.0	null
hsa-miR-106b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
trans-synaptic protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.576
hsa-miR-4503	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
RRP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.32051
IRF1	ENCODE Transcription Factor Targets	1.0	null
PMC6870463-Table_7.xlsx-Family_H_LPS-LPS_treatment_of_BMDMs_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_MSC_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
striatum_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55192
A253	CCLE Cell Line Gene CNV Profiles	-1.0	-2.29274
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX6_SOX6	Rummagene Transcription Factor Associations 2026	1.0	null
SA1-27219007-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZKSCAN5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.3216
mRNA_POU5F1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
Perturb_14211_KO_Sp8/Sp9_SRP084329	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0025
ZSCAN12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60759
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19249
GSE164529_0_v_2_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_PHA-680632_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141184
KDM5B	ENCODE Transcription Factor Targets	1.0	null
Mitral cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.677
CNOT3-19339689-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.7225
PMC5859169__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-S341-1926-SM-3K2BA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.084
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.902172
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87186
External plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.258
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.551
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Cochlear nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06958
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A1A7-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.860868
cdna	GeneRIF Biological Term Annotations	1.0	null
hsa-miR-3677-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE100923_3_v_1_gadd45a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.96258
GTEX-POYW-0426-SM-2XCEV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972177
CALU6	DepMap CRISPR Gene Dependency	1.0	3.49136
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23833
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3577
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9095
Heart rate variability traits (RMSSD)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.1699
synaptic vesicle transport	GO Biological Process Annotations 2015	1.0	null
GSE205163,GSE205164_3_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.02475
ZDHHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43499
HES1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.7898
MCF7_JNJ-26854165_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137803
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	0.921148
ChIP_SUZ12_16625203	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Ovarian Diseases	CTD Gene-Disease Associations	1.0	1.2046
RANGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.46088
YD8	CCLE Cell Line Gene CNV Profiles	1.0	2.68284
Rectum adenocarcinoma_READ_TCGA-AG-3732-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsal motor nucleus of the vagus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01874
JHH2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61946
inferior colliculus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.879707
Heart rate response to recovery post exercise (30 sec)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	5.53979
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-548v	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
ZNF451	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23268
protein homodimerization activity	GO Molecular Function Annotations 2015	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.4049
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44406
hsa-miR-518a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
MCF7_PD173074_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145081
NUDHL1	CCLE Cell Line Gene CNV Profiles	1.0	1.32934
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906989
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.6011
PSN1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853069
C32	Achilles Cell Line Gene Essentiality Profiles	1.0	1.22319
caudal linear (raphe) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07525
GTEX-P44H-0526-SM-2XCF1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69305
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GTEX-T2YK-0326-SM-4DM7D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961508
sensory perception of chemical stimulus	GO Biological Process Annotations 2023	1.0	null
level	GeneRIF Biological Term Annotations	1.0	null
IKZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6732
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Lenalidomide_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0176215
PMC6522222-NIHMS977514-supplement-Sup_Table_15.xlsx-WT3_WT5-Unnamed_0_POU6F2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8452624-41467_2021_25709_MOESM12_ESM.xlsx-ST12-Unnamed_2_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11262
rhombomere 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02
Kidney Chromophobe_KICH_TCGA-KN-8423-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTF2B	ENCODE Transcription Factor Targets	1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
IALM	CCLE Cell Line Gene CNV Profiles	1.0	1.68727
hsa-miR-454	TargetScan Predicted Conserved microRNA Targets	1.0	0.154935
anterior paraventricular nucleus of thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22895
hsa-miR-497	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.190495
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05121
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25266
MCF7_Fasudil_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016007
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain_CT2_CGE 283	HuBMAP ASCT+B Annotations	1.0	null
GTEX-QLQ7-1826-SM-2S1R5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01139
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
hsa-miR-590-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3329
SARS-CoV MA15_Day2-PFU-10^2_None_GSE33266	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.08078
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953096
H3K27me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OB inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.45928
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S32W-2526-SM-2XCB8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56326
Adrenocortical carcinoma_ACC_TCGA-PA-A5YG-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.228812
RPL30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38296
snare complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.605284
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12111
JUND	ENCODE Transcription Factor Targets	1.0	null
Neuronal System	Reactome Pathways 2024	1.0	null
Primary T cells from cord blood	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.3767
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-93	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
ChIP_SUZ12_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05521
HOXA5	JASPAR Predicted Transcription Factor Targets	1.0	null
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	43.575
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.8279
bcl11b_18199763_brain_lof_mouse_gpl1261_gds3178	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.2196
primary motor-sensory cortex (samples)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.897981
ETV2-25802403-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
ADGRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64942
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043012
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NK-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLEKHA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16765
Synaptotagmin	InterPro Predicted Protein Domain Annotations	1.0	null
GATA1-19941826-K562-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07838
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.994
MCF7_Droxinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137353
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21874
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_42_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-J2-A4AD-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-UN-AAZ9-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.25252
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.426397
ZNF143	ENCODE Transcription Factor Targets	1.0	null
Nucleus preopticus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Stratum lucidum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
ELK4-26923725-CHIP-SEQ-MESODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
sensory perception of smell	GO Biological Process Annotations 2025	1.0	null
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68189
GTEX-WYBS-0326-SM-3NM8S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77004
dorsal part of alar p3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16727
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.573552
pontine nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.79261
cellular response to oxygen-containing compound	GO Biological Process Annotations 2023	1.0	null
mantle zone of PThE	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16727
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0005
NCIH838	CCLE Cell Line Gene CNV Profiles	1.0	2.34756
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
open	GeneRIF Biological Term Annotations	1.0	null
clathrin-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.214017
EFM192A	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48636
ventrolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.873027
NCIH838	DepMap CRISPR Gene Dependency	1.0	9.19837
Bed nuclei of the stria terminalis, anterior division, anteromedial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2091
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REH	Achilles Cell Line Gene Essentiality Profiles	1.0	1.50868
PMC11161485-41531_2024_729_MOESM1_ESM.pdf-9-ZNF404_ZNF404	Rummagene Transcription Factor Associations 2026	1.0	null
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90055
MCF7_Trichostatin A_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0131506
MCF7_Ruxolitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130219
MYC	ENCODE Transcription Factor Targets	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34861
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72059
external part of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77818
Lung adenocarcinoma_LUAD_TCGA-53-7624-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
malformation of the heart and great vessels	GWASdb SNP-Phenotype Associations	1.0	0.394376
MCF7_Baricitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.013534
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain_CT2_Inh L1-2 PVALB CDK20	HuBMAP ASCT+B Annotations	1.0	null
COPS7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49322
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7066322-mmc2.xlsx-Sheet1-DEGHDvCTL_MAP2_NES-_SOX2-_symbols_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.06918
GTEX-XQ8I-2026-SM-4BOOL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846849
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
NCI-H1623	COSMIC Cell Line Gene Mutation Profiles	1.0	null
secretory vesicle	GO Cellular Component Annotations 2025	1.0	null
hsa-miR-519d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
NFE2L2-20460467-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A3CH-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r5Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17243
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.60852
KDM4A	ENCODE Transcription Factor Targets	1.0	null
synaptic vesicle exocytosis	GO Biological Process Annotations 2023	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HT-1197	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MCF7_Dasatinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0251291
vesicle-mediated transport in synapse	GO Biological Process Annotations 2023	1.0	null
PMC12619835-41467_2025_66007_MOESM13_ESM.xlsx-Sheet1-Basal_like_KLF5_peaks_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MIR140_OE_GDS3461_575_mouse_C3H10T1/2 fibroblast cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
PRR12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.40824
amygdaloid complex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05954
Superior vestibular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.741
SAOS-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
autosomal genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.047332
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14699
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76731
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.70927
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-6482-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oligospermia	CTD Gene-Disease Associations	1.0	1.04941
GSE134029_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
preopto-hypothalamic band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30887
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01337
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal atrioventricular conduction	GWASdb SNP-Phenotype Associations	1.0	2.08106
NCIH596	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37382
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.96928
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Celecoxib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.021155
exocytosis	GO Biological Process Annotations 2015	1.0	null
SNCA_KO_GDS4153_527_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
regulated exocytosis	GO Biological Process Annotations 2023	1.0	null
TCCPAN2	DepMap CRISPR Gene Dependency	1.0	2.01343
TRNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88178
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47292
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.27146
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.64861
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.977064
E2F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.5151
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cephalothorax	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.582
r2 part of trigeminal sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38842
bladder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.11285
ARNT	ChEA Transcription Factor Targets	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042566
GSE147056_2_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89215
GATA1	ChEA Transcription Factor Targets	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-SYMBOL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Nearest_Ensembl_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H1581	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
Synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.04
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0883
MCF7_Thalidomide_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0177507
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.886042
Heart rate increase in response to exercise	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.95229
PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-ensemblGeneId_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Prelimbic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.131
MCF7_Dasatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0356911
OB mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.47104
Lung squamous cell carcinoma_LUSC_TCGA-60-2706-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.9272
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.29781
Tegmental reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02598
Gastrointestinal system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.551
MASTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1385
Exocytic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.778
mantle zone of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31602
NCI-H1869	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20698
GTEx Nerve 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	1.0	11.0402
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE131649_6_v_0_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Phosphorylase kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.984
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44404
periventricular stratum of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18348
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03709
parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.40008
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10138
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
regulation of transport	GO Biological Process Annotations 2015	1.0	null
GSE142684_4_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
integral component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828935
RNASEH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.95822
Freemartinism	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.435
PMC8423434-mmc7.xlsx-SOX2_Primed-Genes_n_3042_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01876
GTEX-WYJK-0326-SM-3NMA8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14866
MCF7_Tranylcypromine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143498
PMC9974104-jci-133-159940-s017.xlsx-GT3-INCP-GATA3_Co-down-Symbol_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EI-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-222	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78828
all	GWASdb SNP-Phenotype Associations	1.0	0.121447
organelle organization	GO Biological Process Annotations 2015	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE74251_2_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
deep layers of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15348
acids	GeneRIF Biological Term Annotations	1.0	null
COLO 206F	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.48887
H3K27me3_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CardiacMyocytes	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.63075
KASUMI6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77385
GSE131377_1_v_3_spocd1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inner SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.869131
H3K27me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DCAF16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75728
BT474	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.23337
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_upregulated-Ensembl_ID_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_MYBL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
RUNX1-27514584-CHIP-SEQ-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26333
MCF7_Sirtinol_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0180375
ZNF331	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8083
MCF7_PD98059_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130924
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-GATA4_GATA4	Rummagene Transcription Factor Associations 2026	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-143	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GTEX-WH7G-2626-SM-3NMBE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02805
MCF7_Raltitrexed_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146026
anterior (rostral) cingulate (medial prefrontal) cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48329
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.2372
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91788
NB7	DepMap CRISPR Gene Dependency	1.0	6.58609
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SR-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.31387
clathrin-coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPUSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11394
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.926619
MCF7_AZ 960_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172546
Dsl1/NZR complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.61
SNU423	DepMap CRISPR Gene Dependency	1.0	4.08519
RALBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09953
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040717
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.89509
intermediate stratum of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2323
Exocytic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
Heart rate response to recovery post exercise	GWAS Catalog SNP-Phenotype Associations 2025	1.0	2.6
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WBP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59387
MCF7_TMP195_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152141
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03241
18451145-TableS1	GeneSigDB Published Gene Signatures	1.0	null
MCF7_Toremifene Citrate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0117843
ppard_23093780_pancreatic_beta_cells_lof_mouse_gpl1261_gds4320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.183307
Brain_CT2_Inh L1-2 PVALB CDK20	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
H3K9me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_AG-490_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.017321
Visual cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.162
GSE118816_2_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX2-21211035-LN229-GBM	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WHWD-2326-SM-3LK6Q	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905183
DMS-53	COSMIC Cell Line Gene CNV Profiles	1.0	2.06626
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.694946
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8072
GTEX-R55E-0426-SM-2TC65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35349
Arrhythmogenic right ventricular cardiomyopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
IRF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4955
hsa-miR-200c	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
HT-1376	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.44027
syt	GeneRIF Biological Term Annotations	1.0	null
rostral subdivision of medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.836302
Mecom	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.4815
Perturb_14796_OE_Mycn_SRP094656	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.00716
Spastic Syndrome	DisGeNET Gene-Disease Associations	1.0	null
MCF7_Tacedinaline_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.01373
Genital Diseases, Female	CTD Gene-Disease Associations	1.0	1.06952
medial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33168
Gastrointestinal tract	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52Q-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11608
CD33+_Myeloid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.964795
451LU	COSMIC Cell Line Gene Mutation Profiles	1.0	null
protein heterodimerization activity	GO Molecular Function Annotations 2015	1.0	null
EFM19	Achilles Cell Line Gene Essentiality Profiles	1.0	1.1005
MCF7_2-Methoxyestradiol_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124107
GTEX-N7MS-0526-SM-4E3JP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96442
NCI-H1703	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.57471
single-organism membrane fusion	GO Biological Process Annotations 2015	1.0	null
GSE102505_6_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228106_0_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97141
PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-3_E2F2-Gene_E2F2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE130437_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NALM-6	COSMIC Cell Line Gene Mutation Profiles	1.0	null
lung disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.035343
hsa-miR-26b	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
calcium ion sensor activity	GO Molecular Function Annotations 2025	1.0	null
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.92144
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
synaptic vesicle cycle	GO Biological Process Annotations 2025	1.0	null
MCF7_ENMD-2076_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146265
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11615365-41467_2024_54246_MOESM4_ESM.xlsx-RT4-Numb-KD_vs_Ctr-KD-geneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
transporter activity	GO Molecular Function Annotations 2015	1.0	null
ML-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.965227
membrane part	GO Cellular Component Annotations 2015	1.0	null
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848639
SG in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26054
organelle membrane fusion	GO Biological Process Annotations 2015	1.0	null
ChIP_MTF2_20144788	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4228-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.01286
GTEX-R55C-1926-SM-2TF4K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12857
hsa-miR-4251	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
Terminal bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.047
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHLDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12865
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WH-01A-22R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4Q7-1426-SM-3K2B9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09767
Intestinal disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.551
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22787
GTEX-RNOR-0326-SM-2TF51	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8377
UCHL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03626
r6 part of the cochlear column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87204
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE216043_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF140	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03618
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.868489
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847969
layer I of piriform cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44191
PL4	COSMIC Cell Line Gene CNV Profiles	1.0	2.06626
KMOE-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SUZ12-16625203-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-S341-1126-SM-4AD6T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18455
TAL1	ENCODE Transcription Factor Targets	1.0	null
Median preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33801
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.805
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XPVG-1726-SM-4B65W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11002
hsa-miR-3915	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Shee2-The_differentially_expressed_genes_between_the_BARX2_high_and_BARX2_low_group_of_LIHC_patients_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
Perirhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.541
MCF7	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.4095
Posterior chamber of the eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.628
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A4-11A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10437
RAD54B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09273
synapse part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.996855
MCF7_PD98059_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0212851
Lung squamous cell carcinoma_LUSC_TCGA-60-2695-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4496	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Mesend_D2_GATA6-dependent-ENSEMBL_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SNOS-1026-SM-4DM4Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11445
ZNG1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4895
6-phosphofructo-2-kinase/fructose-2,6-biphosphatase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.01
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44227
calcium ion-dependent exocytosis of neurotransmitter	GO Biological Process Annotations 2015	1.0	null
SSBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26228
hsa-miR-548aa	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69106
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35177
hsa-miR-4521	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	1.43775
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.32041
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19495
GTEX-O5YV-1826-SM-2YUNI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26933
asthma	GWASdb SNP-Disease Associations	1.0	0.963873
MCF7_Quisinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0110691
hsa-miR-4298	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
MCF7_Anacardic Acid_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125621
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.906989
NCI-H1563	COSMIC Cell Line Gene Mutation Profiles	1.0	null
KASUMI1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.74307
Septofimbrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01366
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.8725
ZNF217-24962896-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.960574
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07432
SUM229PE	DepMap CRISPR Gene Dependency	1.0	2.68286
TFAP4::ETV1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9327
PMC4387713-supp_gad.255984.114_Table_S5.xlsx-S5E-Down_H3K27me3_DPY30_KD-Unnamed_12_AR	Rummagene Transcription Factor Associations 2026	1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043457
Kidney Chromophobe_KICH_TCGA-KL-8325-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1573	DepMap CRISPR Gene Dependency	1.0	14.4169
H2BK15ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-200b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
regulation of calcium ion-dependent exocytosis	GO Biological Process Annotations 2023	1.0	null
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IA-LM	COSMIC Cell Line Gene CNV Profiles	1.0	2.06626
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_neg_targets-ID_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUJ4-2726-SM-4BOQ1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71183
ZNF263	ENCODE Transcription Factor Targets	1.0	null
ChIP_H3K27me3_17603471_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
arcuate nucleus of medulla, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.17974
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cuneate nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39637
17009876-tableS1b	GeneSigDB Published Gene Signatures	1.0	null
PMC11801220-NIHMS2038999-supplement-16.xlsx-Inh-MEF2C-gene_MEF2C	Rummagene Transcription Factor Associations 2026	1.0	null
496100334_PCx_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.06694
SNARE complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.722
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC	JASPAR Predicted Transcription Factor Targets	1.0	null
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-9	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.31387
MCF7_Crizotinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0115119
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860163
regulation of vesicle-mediated transport	GO Biological Process Annotations 2015	1.0	null
OCIAML3	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.06203
Periventricular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15452
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.959504
hsa-miR-452	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
MCF7_UNC1999_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0112942
LPIN1_OE_GDS2291_587_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
supraventricular arrhythmia	GWASdb SNP-Phenotype Associations	1.0	2.08106
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91932
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6914
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IKBKB_Constitutional activation_GDS4119_621_mouse_Prostate epithelium	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.52635
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
preoptic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06422
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-ER_ZNF_GATA3-Gene_Name_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7314-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCIAML5	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.67083
Synaptic vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.781
SMAD4-21799915-A2780-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2913-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-HAND1_neg_targets-Gene_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0913
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4995-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0187
chr12_33416072_CACCATTCTCTTTTATTTGTTGTTGTTGAGACAGAGTCTCACTCTGTCACCCAGGCTGG_C_b38	GTEx eQTL 2025	1.0	3.33257
TMEM68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02112
TRIM28	ChEA Transcription Factor Targets	1.0	null
H3K27me3_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A5QE-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_BRD4770_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0191701
Zic1::Zic2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.8959
MTF2-20144788-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4994-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
vesicle organization	GO Biological Process Annotations 2015	1.0	null
H3K27me3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X3Y1-2426-SM-3P5Z7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20651
GSE143499_0_v_1_gata6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KPNB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67045
medial superior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02196
membrane-bounded vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.260566
Adrenal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.385
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-U4B1-1426-SM-4DXTX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.957531
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02271
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6497
GTEX-QDVN-2226-SM-2S1PM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982481
Preoptic area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.558
Skin Cutaneous Melanoma_SKCM_TCGA-GN-A26D-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19759
GPR120_KO_GDS4830_414_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.277549
TOP2B-26459242-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE256181_2_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Transcriptional Regulation by NPAS4	Reactome Pathways 2024	1.0	null
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_Pelitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150541
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vesicle-mediated transport	GO Biological Process Annotations 2015	1.0	null
GTEX-O5YT-1726-SM-3NMD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03548
Venom apparatus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.838
bounding membrane of organelle	GO Cellular Component Annotations 2015	1.0	null
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.975058
GSE234514,GSE234516_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
DOR 13	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.69106
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4225-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Cimetidine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0189447
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3440-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53532
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12985
MCF7_Decitabine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0131402
CAOV4	Achilles Cell Line Gene Essentiality Profiles	1.0	1.3262
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.922284
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
Olfactory receptor neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.298
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0115
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.383
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.852335
UBL7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08893
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.771879
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
SNAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80207
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-1626-SM-3DB74	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80377
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
presynapse	SynGO Synaptic Gene Annotations	1.0	null
Inhibitory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.428
GTEX-UJMC-1926-SM-3GADS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57941
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.922986
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RNF2-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
GSE219195_4_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
amino	GeneRIF Biological Term Annotations	1.0	null
core of nucleus accumbens	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.01213
K562_Tazemetostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150567
GTEX-OHPN-2926-SM-3LK65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08369
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-8196-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040923
K562_Droxinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149997
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5559-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Heart rate response to recovery post exercise (40 sec)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	5.6699
GTEX-X4EO-2726-SM-4E3HS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6718
H3K9me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12735
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.856105
lateral portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.93921
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-A5NJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Basal_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_WHSC2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW900	CCLE Cell Line Gene CNV Profiles	1.0	1.99376
membrane organization	GO Biological Process Annotations 2015	1.0	null
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05008
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A4ZT-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE119978,GSE180930_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral periolivary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2276
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-MYCN_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
paraventricular nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0336
GTEX-XGQ4-2526-SM-4AT57	GTEx Tissue Sample Gene Expression Profiles	1.0	0.989002
MX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13148
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4524	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-X4EO-0126-SM-3P5YN	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22596
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039826
GSE175787_5_v_0_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04971
SNU620	CCLE Cell Line Gene CNV Profiles	-1.0	-2.75398
Lung adenocarcinoma_LUAD_TCGA-L9-A443-01A-12R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Curcumin_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148752
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1273d	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34861
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-LT-A5Z6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4UY-1426-SM-4AD6Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988961
Syntrophin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.008
r6 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.65713
olfactory bulb, principal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.06683
LS1034	CCLE Cell Line Gene CNV Profiles	1.0	1.5569
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
l23	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.074
metal ion binding	GO Molecular Function Annotations 2023	1.0	null
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bronchial disease	GWASdb SNP-Disease Associations	1.0	0.963873
MCF7_Aurora A Inhibitor I_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0208447
SSTR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16734
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853069
Anterior cingulate area, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8744
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
HEC1	DepMap CRISPR Gene Dependency	1.0	9.64989
GRANTA519	CCLE Cell Line Gene CNV Profiles	-1.0	-1.77756
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	2.09859
GSE74383_1_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ebolavirus(EBOV)_5day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.6124
H3K27me3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7750-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08218
Acute Myeloid Leukemia_LAML_TCGA-AB-2887-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-20b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
FIBIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2134
OCIAML2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.26485
regulation of regulated secretory pathway	GO Biological Process Annotations 2025	1.0	null
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.40287
Lung squamous cell carcinoma_LUSC_TCGA-22-5477-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
trigeminal	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.46784
orbital frontal cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.956823
WM1552C	COSMIC Cell Line Gene CNV Profiles	1.0	2.06626
496100335_PCx_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.56169
Lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14457
olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.921199
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
C1orf109	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10252
rat	GeneRIF Biological Term Annotations	1.0	null
GTEX-TML8-1626-SM-32QOO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78536
Synaptic vesicle, readily releasable pool	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.915
NCI-H810	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Synaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.255
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lateral septal nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21746
MCF7_SL-327_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131786
RPLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24216
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EP-0726-SM-3P5YJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06246
GTEX-WFG8-2526-SM-3GILR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19557
GTEX-SIU8-0326-SM-2XCDR	GTEx Tissue Sample Gene Expression Profiles	1.0	2.32191
primary motor-sensory cortex (samples)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.987008
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10113
H3K27me3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
establishment of organelle localization	GO Biological Process Annotations 2015	1.0	null
CRO-AP3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83715
MDA-MB-361	COSMIC Cell Line Gene Mutation Profiles	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12-16625203-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-2113	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
PMC11801220-NIHMS2038999-supplement-15.xlsx-Exc-PBX3-gene_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
SNU899	CCLE Cell Line Gene CNV Profiles	-1.0	-1.70499
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.951557
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
heart	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.01839
Metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.509691
GTEX-T2IS-1126-SM-4DM6Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41799
PLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36935
MCF7_CYC116_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138282
P300-19829295-ESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ARNT-22903824-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TCF4	ChEA Transcription Factor Targets	1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.13015
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SUZ12	ChEA Transcription Factor Targets	1.0	null
NHE3_Deficiency_GDS3323_599_mouse_Colon	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
RUNX2	ChEA Transcription Factor Targets	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cardiac arrest	GWASdb SNP-Phenotype Associations	1.0	1.54299
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07926
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
chemical synaptic transmission	GO Biological Process Annotations 2025	1.0	null
central part of CEl	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.960968
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06271
regulation of secretion	GO Biological Process Annotations 2015	1.0	null
G122	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10505
Main olfactory bulb, inner plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.27445
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48856
K562_Trametinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0179155
GSE128076_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	1.0	null
clone	GeneRIF Biological Term Annotations	1.0	null
corpus striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.424581
H3K9ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SDE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13459
ATP5MG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14492
caudal putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52009
Rectum adenocarcinoma_READ_TCGA-AG-3742-11A-01R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Human - Motor Cortex - Cluster - SST+ DEFB108B+ Layer 1 GABAergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
hsa-miR-503	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
Medial preoptic nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.00409
Sarcoma_SARC_TCGA-KD-A5QT-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06279
hsa-miR-3157-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2188
single-organism organelle organization	GO Biological Process Annotations 2015	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SW480	Achilles Cell Line Gene Essentiality Profiles	1.0	1.19748
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Presynapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.916
GTEx Nerve 20-29 vs 50-59	GTEx Tissue-Specific Aging Signatures	1.0	9.59749
POU5F1	ChEA Transcription Factor Targets	1.0	null
H3K9me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF4-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.07452
MCF7_Fulvestrant_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0226693
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02192
mediodorsal nucleus of thalamus_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22
LRRC8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15633
YKG1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.03206
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9533694-MOL2-16-3410-s013.xlsx-FIR20vsREST_DEMs-FIR20_vs_REST_DEMs_Up_REST	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM243	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69898
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66805
r2 part of vestibular sensory column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21577
SUZ12-18974828-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Bed nuclei of the stria terminalis, posterior division, interfascicular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02629
GSE234340_10_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dilated cardiomyopathy	GWASdb SNP-Phenotype Associations	1.0	2.08106
hsa-miR-3918	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
exocytic vesicle	GO Cellular Component Annotations 2023	1.0	null
Splenic Diseases	CTD Gene-Disease Associations	1.0	1.01663
H513	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-RU1J-0526-SM-46MUT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839557
Geep	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.516
PMC11250262-41588_2024_1798_MOESM4_ESM.xlsx-ST18_665_top_menarche_genes-gene_ST18	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WOFM-1626-SM-3MJFX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05757
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02263
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
biological_process	GO Biological Process Annotations 2015	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.853069
Paraventricular nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20562
Anterior commissure	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.879
Lung squamous cell carcinoma_LUSC_TCGA-34-5240-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTF2-20144788-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79909
intermediate stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08218
hsa-miR-221	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.16118
MCF7_MK-0752_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0193151
Primary somatosensory area, lower limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18782
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NV-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A-VN-1203-2004(H5N1)_Day2-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.74834
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.223
H4K20me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27524
Lung adenocarcinoma_LUAD_TCGA-91-6828-11A-01R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Tubastatin A HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0137967
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
H3K27me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6400843-Table_5.xls-C_FOXM1_Correlated_genes-Symbol_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.1715
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40167
seminal vesicle	HPA Tissue Protein Expression Profiles	1.0	1.26085
Perturb_14906_KD_LIN41_SRP032743	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.6657
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18669
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06846
tachycardia	GWASdb SNP-Phenotype Associations	1.0	2.08106
Mesosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.789
subthalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.966638
ChIP_SUZ12_18974828	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
E2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0544
PMC6335596-mmc2.xlsx-RNA-seq_Day_3_GATA6_Het-Genes_significantly_differentially_expressed_between_H9_and_GATA6_4ins_at_day_3_in_RNA-seq_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CALU1	CCLE Cell Line Gene CNV Profiles	1.0	1.44329
GSE154074_5_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
anterior digastric muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02263
MCF7_Curcumin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0129751
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_TG101209_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0121281
orbital frontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.995017
GSE256181_1_v_3_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SCYL1_knockdown_194_GSE57646	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.22252
GTEX-Q2AG-0011-R2A-SM-2HMIT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.891619
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548t	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
PMC4082627-12864_2014_6197_MOESM8_ESM.xlsx-GATA3_only-Gene_Name_GATA3	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
Nuclear inclusion body	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.536
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PBX3_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.5464
PMC8379183-41467_2021_25326_MOESM9_ESM.xlsx-genes_with_only_SALL4_peaks-Protein-coding_genes_that_show_only_CUT_RUN_peaks_with_2_SALL4_antibodies_and_no_other_antibodies_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
Exocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.048
Primary somatosensory area, upper limb, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17243
REST	ENCODE Transcription Factor Targets	1.0	null
PMC10170086-41598_2023_34519_MOESM6_ESM.xlsx-Sheet3-The_overlapping_genes_between_significantly_co-expressed_genes_and_significantly_differentially_expressed_genes_of_BARX2_in_LIHC_BARX2	Rummagene Transcription Factor Associations 2026	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10636
SUDHL8	DepMap CRISPR Gene Dependency	1.0	4.19037
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZR-06A-21R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBLL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44413
MCF7_UNC0379_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165802
GTEX-XUW1-1826-SM-4BOQD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03146
CAMA-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE102505_1_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33058
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.990669
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_PD173074_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0193375
Acidocalcisome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.95
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral pallium	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31761
POU5F1-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.846614
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06662
697	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.51992
basal ventral medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25135
pituitary	GTEx Tissue Gene Expression Profiles	1.0	0.866011
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Main olfactory bulb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94386
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00125
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54997
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10909
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-610	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
cell part	GO Cellular Component Annotations 2015	1.0	null
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24108
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.87307
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
cytoplasmic vesicle part	GO Cellular Component Annotations 2015	1.0	null
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUZ12-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.997441
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.395
Brain_CT2_MGE 240	HuBMAP ASCT+B Annotations	1.0	null
central part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12774
VMCUB1	DepMap CRISPR Gene Dependency	1.0	3.19761
heart conduction disease	GWASdb SNP-Disease Associations	1.0	2.11849
C32	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.921637
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lipid binding	GO Molecular Function Annotations 2015	1.0	null
supraventricular tachycardia	GWASdb SNP-Phenotype Associations	1.0	2.08106
regulated exocytosis	GO Biological Process Annotations 2025	1.0	null
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.22691
GTEX-WEY5-2226-SM-3GILQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28486
CEBPB-26923725-CHIP-SEQ-MESODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.882675
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.571
PPARD_KO_GDS4320_619_mouse_Pancreas	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-PLZ5-1626-SM-3NB21	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28507
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_PF-573228_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147431
UMUC16	DepMap CRISPR Gene Dependency	1.0	5.20361
hsa-miR-4693-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15781
GSE131649_6_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
MCF7_S3I-201_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0133806
r3 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0529
hsa-miR-107	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
signal release	GO Biological Process Annotations 2015	1.0	null
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.04656
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H6PD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26448
Acute Myeloid Leukemia_LAML_TCGA-AB-2857-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8T8-0426-SM-3DB8X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54736
Postsynaptic Golgi apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.769
triangular septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46066
GSE224439_1_v_3_adagrasib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PLEKHO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64746
GSE88819_5_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05077
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03809
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE160817_7_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
Pacemaker cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.428
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of r2Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38666
KKU213	DepMap CRISPR Gene Dependency	1.0	3.29133
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.81333
chronic obstructive pulmonary disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.035343
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6336
Ventral posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21654
H3K27me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.833739
NFE2L2-20460467-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CHLA57	DepMap CRISPR Gene Dependency	1.0	2.36176
GTEX-XMK1-2426-SM-4B66I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89195
hsa-miR-889	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
CCM2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30972
VZ in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.851125
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PH-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.1283
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966427
OB granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.51351
GTEX-RTLS-1226-SM-46MUP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0266
IRF4-20064451-CD4+T-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
regulation of dopamine secretion	GO Biological Process Annotations 2023	1.0	null
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPAR-Beta_DELETION_GDS4320_363_mouse_Pancreatic beta-cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M5-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27219
hsa-miR-527	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7662-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04834
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.976059
AHR-22903824-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_A-366_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0177439
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.22691
inferolateral temporal cortex (area TEv, area 20)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05636
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TRIM28_knockout_302_GSE32224	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.27288
GTEX-WL46-0426-SM-3TW8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00542
MCF7_Momelotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0138752
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941262
Perturb_9526_KO_P2ry1_SRP342865	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.9199
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850725
GTEX-R55F-0226-SM-48FCI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15565
GSE78199_2_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K8-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4698	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
PCI38	DepMap CRISPR Gene Dependency	1.0	2.56597
SNU475	CCLE Cell Line Gene CNV Profiles	1.0	2.08032
GSE134029_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S4Z8-1926-SM-3K2AR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43681
Brain_CT2_LRL 320	HuBMAP ASCT+B Annotations	1.0	null
MET	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98701
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040854
Intercalated nucleus of amygdala	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.27627
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974126
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.919236
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.26774
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67602
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.73745
MXI1	ENCODE Transcription Factor Targets	1.0	null
SEKI	DepMap CRISPR Gene Dependency	1.0	2.01314
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PA-TU-8902	COSMIC Cell Line Gene CNV Profiles	1.0	2.06626
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40931
single-organism membrane organization	GO Biological Process Annotations 2015	1.0	null
transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.680719
MCF7_Zileuton_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148511
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34861
mouse	GeneRIF Biological Term Annotations	1.0	null
Perturb_8944_KO_RB1_SRP220467	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	9.6917
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBL1-22424771-293T-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RBBP7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65949
deep layers of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.50005
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.0063
SG in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.895463
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-SNMC-1126-SM-4DM5M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940352
CENPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19212
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.79969
HCC1534	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828935
MCF7_Flavopiridol HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175076
neurotransmitter secretion	GO Biological Process Annotations 2023	1.0	null
TRIM28-17542650-NTERA2-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-1126-SM-4AD4N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836435
septopallidal core nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13633
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.22691
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB453	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.801469
MCF7_Ellagic acid_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142551
pparb_23093780_pancreas_lof_mouse_gpl1261_gds4320	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.183307
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HAND1_cust_neg_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Cimetidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0215562
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
localization	GO Biological Process Annotations 2015	1.0	null
Primary motor area, Layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35684
GTEX-XBED-2526-SM-47JYD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69184
H3K9ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-4465	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
MEF2A	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80552
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Nintedanib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146306
sensory perception of chemical stimulus	GO Biological Process Annotations 2025	1.0	null
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Accessory olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54908
GSE151083_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SU-DHL-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01487
PMC5894239-12864_2018_4591_MOESM9_ESM.xlsx-ST12_mir_upregulated-Gene_name_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
primary atrial arrhythmia	GWASdb SNP-Phenotype Associations	1.0	2.08106
HECA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09184
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.299452
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16789
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
membrane fusion	GO Biological Process Annotations 2015	1.0	null
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.83644
NCI-H1435	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NLGN4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01613
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KE-37	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CP66-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
amygdalostriatal transition area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	3.07347
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X638-0426-SM-47JY2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41682
rectum	HPA Tissue Protein Expression Profiles	1.0	1.26085
SNU-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.38785
ChIP_POU5F1_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.862283
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4295	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
TASK1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SREK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46688
lateral orbital frontal cortex (area 12/47)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.927434
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.881468
RNF2-27304074-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
lung disease	GWASdb SNP-Disease Associations	1.0	0.384023
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, posterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06349
mantle zone of r6Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8744
GSE185163_3_v_1_clic4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Heart Rate	DisGeNET Gene-Phenotype Associations	1.0	null
GSE131161_3_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AHR-22903824-MCF7-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-20a	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
496100469_TCx_no dementia_TBI_89_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.26602
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.41363
H3K27me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02372
anterior group of nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.850772
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
establishment of synaptic vesicle localization	GO Biological Process Annotations 2015	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QCQG-2026-SM-2S1PH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47345
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06959
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GATA2-19941826-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-382	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
SRSF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00851
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P78B-1726-SM-3P5ZV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.990384
Hypertrophy	CTD Gene-Disease Associations	1.0	1.35127
GSE134029_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RPMI-7951	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2809
hsa-miR-15a	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
protein dimerization activity	GO Molecular Function Annotations 2015	1.0	null
ChIP_H3K27me3_20682450_humanESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE199606_5_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
frame	GeneRIF Biological Term Annotations	1.0	null
NCIH660	CCLE Cell Line Gene CNV Profiles	-1.0	-1.48112
Growth Disorders	CTD Gene-Disease Associations	1.0	1.02262
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	98.4832
CREB1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal septopreoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09466
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Y-11A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Irf1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.0091
GSE216043_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63298
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.187
MCF7_BMS-754807_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0118689
ion binding	GO Molecular Function Annotations 2015	1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.237
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.951557
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A2C5-01A-12R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCI-LY7	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SKNO1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.6657
r3 part of lateral vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20405
cellular response to calcium ion	GO Biological Process Annotations 2023	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF487	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43096
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07787
PFKFB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48455
Medial preoptic nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54357
Morning person	GWAS Catalog SNP-Phenotype Associations 2025	1.0	3.01549
E2F6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.84
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.60141
SKHEP1	DepMap CRISPR Gene Dependency	1.0	2.17307
NAAA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00058
UACC893	DepMap CRISPR Gene Dependency	1.0	5.04672
GTEX-X585-0426-SM-4E3JZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47863
hsa-miR-4699-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-S33H-2326-SM-2XCB3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46325
superficial stratum of r3Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20722
496100609_TCx_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.25943
calcium ion binding	GO Molecular Function Annotations 2015	1.0	null
MCF7_SB431542_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0109195
NBPF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10626
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.841435
hsa-miR-3658	TargetScan Predicted Conserved microRNA Targets	1.0	0.632343
neurotransmitter secretion	GO Biological Process Annotations 2025	1.0	null
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.880881
MCF7_Tranylcypromine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169115
homology	GeneRIF Biological Term Annotations	1.0	null
presynaptic dense core vesicle exocytosis	SynGO Synaptic Gene Annotations	1.0	null
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Sinus node	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.429
JARID2-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.26743
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07927
GTEX-NFK9-0426-SM-2YUNK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05516
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45174
SNAI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7468
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.882358
GTEX-PLZ6-1126-SM-3P5ZR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85593
Presynaptic membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.149
H3K27me3_iPS-20b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MCF7_TMP195_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145326
GTEX-QEL4-0426-SM-3GACZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29206
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Large intestine	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PPARD	ChEA Transcription Factor Targets	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8436-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE218580_1_v_4_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EIF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19318
transport	GO Biological Process Annotations 2015	1.0	null
intermediate stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.14183
zona incerta	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.971449
PMC8755441-mmc3.xlsx-IRF7-Up-JARID2_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H2172	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
MCF7_Carmofur_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0123915
cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
r1 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30451
PANC-04-03	COSMIC Cell Line Gene Mutation Profiles	1.0	null
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7166
regulation of cellular localization	GO Biological Process Annotations 2015	1.0	null
Sarcoma_SARC_TCGA-WP-A9GB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAB3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14333
Acute Myeloid Leukemia_LAML_TCGA-AB-2899-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.0673
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.980443
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.838703
H3K27me3_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r2Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21577
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51697
FGFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22062
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.454
LY2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.7765
Mastitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
GTEX-XQ8I-2326-SM-4BOQC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01883
MYCN-27167114-CHIP-SEQ-NEUROBLASTOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r3BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20097
H3K4me1_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Sorafenib Tosylate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156804
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain_CT2_LRL 320	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4834-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WEY5-1526-SM-4LMJF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19261
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100589_PCx_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.19517
r3 part of reticulotegmental nucleus, shell portion	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71254
abnormal circadian rhythm	MPO Gene-Phenotype Associations	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2849-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
calcium-dependent phospholipid binding	GO Molecular Function Annotations 2023	1.0	null
syntaxin binding	GO Molecular Function Annotations 2023	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of secretion by cell	GO Biological Process Annotations 2015	1.0	null
GTEX-XPVG-2826-SM-4B66J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22359
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10437
GSE145915_5_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
brain disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044886
GSE66931,GSE73382_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Sick sinus syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.334
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27615
MCF7_Danusertib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153748
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F6-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF227	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37908
morphine_mus musculus_gpl6246_gse17731	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
amygdaloid complex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11753
MCF7_Avagacestat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126165
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0416
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042654
Suprachiasmatic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.589
MCF10F	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.1369
hsa-miR-589	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
RBBP5	ENCODE Transcription Factor Targets	1.0	null
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.96272
ZNF16	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.8343
mantle zone of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.06857
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-186	TargetScan Predicted Conserved microRNA Targets	1.0	0.336728
Adrenocortical carcinoma_ACC_TCGA-OR-A5JX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
NRF2-20460467-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Ventral posterolateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0892
intrinsic component of membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07927
cellular response to metal ion	GO Biological Process Annotations 2023	1.0	null
MCF7_Fluorouracil_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0161382