association	dataset	threshold value	standardized value
regulation of calcium ion-dependent exocytosis	GO Biological Process Annotations 2025	1.0	null
GSE239688_4_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE227592_8_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PARPBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37542
ALKBH5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49079
NR4A2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4308
DTYMK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83299
TBC1D7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80365
BICDL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71548
LSR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01669
PMC12775252-18_2025_5991_MOESM3_ESM.xlsx-Sheet1-Supplementary_Table_2_Up-_and_down-regulated_genes_in_TCF7L2-depleted_EVT_compared_to_control_EVT_TCF7L2	Rummagene Transcription Factor Associations 2026	1.0	null
TMEM218	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15671
LTBR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42324
TMEM263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88813
GSE206502_2_v_1_igf2bp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
WASHC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21047
CACNA2D2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36247
TFG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44266
SMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69444
GSE102505_6_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PKIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.45742
HOXC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1613
DAAM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87991
LAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27674
KIAA1586	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68564
GSE235066_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF263	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59099
TIMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66638
GSE146982_4_v_5_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ELL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74334
FANCM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4225
ZNF530	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.1937
COMMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37789
NKX2-5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77096
RAB11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13226
DFFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4149
GSE140997_4_v_5_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146982_4_v_5_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF669	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.92
CLSTN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07027
GSE182680,GSE182683_0_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE103309_2_v_0_ube3a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIM45	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28868
RBPMS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94237
EEF1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47438
TAFAZZIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50286
MPHOSPH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23419
GSE149901_3_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58418
NFATC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42591
GSE144745_0_v_1_mettl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LRCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55599
MAP3K12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50594
B4GALT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74072
PDLIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09859
LIG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89971
GSE149359_2_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
JMY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57921
THYN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87374
GSE198982,GSE198986_1_v_2_daunorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZC3H18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52255
TGFBRAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75663
CCDC80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06251
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
METTL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18039
EEF1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26535
RNF135	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71105
GSE81796_0_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111247_2_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTAGE9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97759
RABEPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92837
MAP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92043
GSE103068_0_v_1_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PIGW	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81591
GSE111247_0_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UNC93B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37813
HOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.7207
SPTSSA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98175
MRTFA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53028
MMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3204
KLF14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	116.148
SLC29A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52274
GSE140997_4_v_8_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_5_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF213	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	106.971
GTF2E1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2398
GSE197630_1_v_0_ruvbl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135514_8_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC12A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77894
ZNF324	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1127
CASD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48667
ZBTB24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.2609
NDUFS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22883
CNNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11913
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.484
KDM5D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.149
FAM111A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94951
TAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71659
NUTF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23342
PPP1R18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66802
GSE70935_3_v_5_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
APAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.56557
IL11RA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.52129
SMARCD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08353
RHOBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72479
TNFRSF11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87197
HSPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28655
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXD4L6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33678
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157383_3_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ROM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36337
GSE119978,GSE180930_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SNRNP200	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24322
ZBTB33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66627
HSFX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47124
GSE77108_4_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE77108_5_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.55058
MEST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44312
ZNF682	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	73.551
ZNF569	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.59402
HAPLN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03769
WDR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11012
PTCH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89457
GSE140997_4_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KIF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55566
PAFAH1B3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50807
H4C12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36844
GSE173394_1_v_0_nfatc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHE22	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3372
EED	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41254
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ESRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62265
CREBBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.34461
MGAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80514
GRHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2013
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DNAJC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13449
CDK11A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09487
B4GAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.545
MRPL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08904
C7orf25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9081
GRPEL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40316
RHPN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37257
TMEM35A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55409
RTL10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91968
LIMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39699
GSDMD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02334
UGT3A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33337
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	1.0	null
RCBTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33828
KRT18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04335
ATP11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26496
NECTIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06264
GSE140997_4_v_6_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102505_1_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40878
LPAR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05882
RRAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.04921
VEZT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39474
EVX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.6101
GSE158834_10_v_6_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
SP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	142.993
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
HOXA4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.9264
FBXL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.09807
INHBE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15337
MSH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53925
PCDHB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.99657
STX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20183
GSE77108_6_v_1_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CASTOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.17335
CDC42EP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56403
MRPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91872
MARVELD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23216
TFAP2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	169.117
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08346
PTDSS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07784
DCUN1D5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82637
PPIH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89792
RPL37A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13134
GEMIN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.7697
GP1BA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30286
NKX2-8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.79801
OVOL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08697
GSE221742,GSE221743_1_v_0_sipa1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NKRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.93395
ATG16L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.253
LEFTY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24044
SEMA4D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5526
ZNF611	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27981
SUGP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.81759
GSE227592_10_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFE2L3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25572
TEAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19585
KMT2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47757
TRIP13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60481
GSE233679_14_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
FGD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43516
TAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40154
GSE166783_3_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TFAP2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	169.5
E2F5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24915
GLIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.7183
ESYT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.67207
ZNF138	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.06558
TTC14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27209
PTTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30054
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GDF9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6957
CES2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45617
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0381
GSE239688_4_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEMIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.81972
OXER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71094
GSE132369,GSE132371_3_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
LYAR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.0653
CREB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94741
CCDC74B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69408
RAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41205
KLF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	96.6929
RNF149	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.5899
CIBAR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32133
STPG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.29764
CPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00659
BCL11B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.02641
TAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22409
ZNF281	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	143.184
MED22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63369
PHB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44215
KLHL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42486
NR4A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54497
GSE133516_5_v_6_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199204,GSE211619_4_v_3_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF418	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.95233
ZNF674	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80907
EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5271
CTSC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47958
ZNF260	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67873
GSE109565_12_v_4_glyphosate_human	RummaGEO Drug Perturbation Signatures	1.0	null
TGDS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8914
GSE221327_6_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM175	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92331
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE172016_2_v_5_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
GLRX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03568
secretory vesicle	GO Cellular Component Annotations 2025	1.0	null
GSE216413_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE227592_4_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE229070,GSE229071_0_v_2_sotorasib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TET1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31397
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TTC30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27043
GSE140997_2_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	1.0	null
SP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	134.565
GSE233679_14_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217526_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NECAB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6085
GALR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00574
RAPH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89707
UTY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.03709
MAU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63722
USE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66545
SNRNP40	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69059
GSE112202_5_v_2_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCDC102A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2439
GSE182680,GSE182683_5_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
CASKIN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.29922
GSE240386,GSE242143_1_v_5_morc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.9375
GSE167474_1_v_0_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
MSH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26465
KBTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33503
ESPN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00622
GSE233679_5_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ACAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.36519
MAP2K2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16679
SYNDIG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61782
SHD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20229
GSE233679_6_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
LMBR1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28878
PLA2G15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17833
C6orf136	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50363
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE233679_14_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE196117_1_v_7_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_8_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
FAM162A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25186
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44576
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MED30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.46039
GSE227592_8_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_14_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
STOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64437
YBX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33287
ANAPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11679
DMXL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.12007
NOL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31852
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44029
CLDN15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03005
GSE246660_1_v_0_glycerol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
calcium-dependent phospholipid binding	GO Molecular Function Annotations 2025	1.0	null
GSE233679_12_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEx Thyroid 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	4.21581
DCP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88693
PATZ1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	161.528
SMIM19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.24732
IQCB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.62971
TTPAL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25576
MPHOSPH6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.00714
SNAI2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7559
ARFGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10512
DUSP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08819
GSE158834_10_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
PTBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8022
ZNF454	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	156.89
GTF2I	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54951
APIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73086
LONP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35848
GSE132369,GSE132371_1_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE236003_2_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RAB31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90065
TUBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11831
NSMCE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74991
MRNIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35765
GSE158632_2_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE233679_14_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE227592_2_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NFS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59539
MYH9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30811
MCM3AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32819
DPH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63266
FBXL18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84608
PHLDB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82281
GSE85565_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF320	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	210.092
KLHL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86324
MTFR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54292
GSE119345_0_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202434,GSE202438_9_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PEG10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40482
GSE102870_7_v_0_nr1h4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE238018_3_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
RNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7738
NR4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98694
PMC12178937-mmc6.xlsx-L_MT1_KDvsD_MT1_KD_deg_all-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
EPB41L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.97883
RNASE6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47218
TTLL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66168
GTF2E2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58853
PHF12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.26067
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF524	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2507
EP300	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55475
EOGT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44711
MAGED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83445
DNAJC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20519
GSE248887_0_v_1_dkk1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71186
SOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58067
GSE132369,GSE132371_2_v_0_cccp_human	RummaGEO Drug Perturbation Signatures	1.0	null
ARL8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0472
SMIM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76027
BTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5327
HSPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32775
KMT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21814
GSE164529_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF354C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33716
ANKZF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.55118
ZIC1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.6355
GSE233679_14_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIX5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.35075
DDX42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37235
FDFT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2566
GSE164529_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
SELENOM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23882
CCDC50	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51726
IL13RA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.71068
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169205_0_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE77108_4_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GOLGA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92419
OBI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86904
GSE184399_0_v_3_cnot1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135514_8_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZNF738	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74262
ACAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06862
BTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.05649
GSE233679_6_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DSP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3148
PXYLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01719
GSE186471_1_v_0_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YPEL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95307
KLF13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.4461
SLC45A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01445
TIGD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28552
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
LMAN2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20448
EVI5L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.59448
RPL13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19015
HLX	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98542
CTBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44154
GSE146982_4_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PSMA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55069
MTMR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84291
HSPB9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.59726
CKAP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28762
WDR59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13998
IAH1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41639
GSE125011_0_v_2_cd83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SRRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4969
SPIB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.33099
GSE218060_7_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZDHHC22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14626
GSE233679_12_v_2_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ENDOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1668
KLF12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	141.554
GSE233679_6_v_13_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE79572_0_v_1_pax8_human	RummaGEO Gene Perturbation Signatures	1.0	null
HBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.54714
SLC5A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2653
ANLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58428
GSE228430_1_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.4719
VCX3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77204
CRLS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65962
EID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66236
MT-ND4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28111
TRMT9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.78002
RAB3GAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58578
CSNK2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09247
GSE146982_4_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37821
FOXA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05461
HOXB4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.2458
EPB41L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36315
GSE102505_6_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
XAB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.65916
UBXN10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58143
KLF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	90.7937
SLMAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.30909
LYL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37308
SARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84337
GSE77108_8_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDK5R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48425
GSE174498,GSE174500_0_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MUC3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88505
ZIC5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	69.8417
GSE132694,GSE132717_0_v_2_meis1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ADCK5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8061
APRT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51868
RPS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41909
VWDE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.81369
RIPOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11223
AGPAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85629
E2F8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.98573
SP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	132.651
GSE142210_3_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GPT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46736
TMEM44	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28658
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE236504,GSE236505_0_v_1_atmin_human	RummaGEO Gene Perturbation Signatures	1.0	null
HMGCL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90213
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
AACS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48736
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RNF166	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01727
TACSTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33541
GSE196117_6_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148321,GSE169423_0_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE186287_1_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
N4BP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07311
DPPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42266
SPRR2F	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57296
MITF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.05606
THUMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.15321
H2BC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.32958
POMGNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18728
GSE166783_1_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE156454_0_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE178532_2_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE241402_0_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
SEMA7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16944
GPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.22996
GSE238018_1_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_7_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZKSCAN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19318
GSE241108_1_v_0_sulfasalazine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRPF19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.28571
RBM8A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82079
GPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.8437
GSE221327_8_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
RPS6KB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21915
GSE147366_3_v_5_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
MT2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34936
DGCR6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84243
PUM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34931
DEPDC1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56813
GSE135030_11_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.64019
GSE167474_2_v_0_naa40_human	RummaGEO Gene Perturbation Signatures	1.0	null
TMEM168	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.966
E2F3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11071
SLC11A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49003
TMBIM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19775
GSE155031_6_v_3_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE94849_1_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CCNE2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04909
PCMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30697
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
XYLT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84754
ZNF234	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08788
INCENP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57197
GSE182680,GSE182683_5_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE193258,GSE193259_2_v_14_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
calcium ion sensor activity	GO Molecular Function Annotations 2025	1.0	null
CCIN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85855
PMC10353540-Table_1.xlsx-HCC1954_AR_vs_HCC1954_A-ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE102505_6_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UCP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.10632
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
CPTP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.60589
PINK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46246
TAF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33434
ARHGEF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48697
GSE128844_0_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158632_3_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
MT-CO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.78704
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.18076
FNBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51817
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF692	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	54.5155
TBC1D9B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06743
GSE223893_1_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
DNAJB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2294
MICALL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44789
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_10_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DPPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54405
GSE135030_11_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NPDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85185
WDR86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.87302
ODAD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86476
DNAJC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.46276
RPS21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55447
FHIP1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83906
RNF216	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54621
MED4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3654
SKIC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.79275
GSE226249_5_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MSI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45606
GSE111247_11_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
STAU1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24406
GUCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4847
MFN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96321
ALX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43293
GSE140997_4_v_1_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.348
CIART	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7545
AIDA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34547
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SLC31A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.96938
REM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13851
GSE188382_4_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PLAGL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	64.7273
ZNF625	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76967
GSE189772,GSE189773_3_v_2_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
MED8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54906
KIAA1958	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10464
GSE233679_5_v_7_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
AGAP6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57787
ABRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22944
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169205_3_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
exocytic vesicle	GO Cellular Component Annotations 2025	1.0	null
TJP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6903
RANBP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50677
NLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63227
DHRS4L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3019
GSE221327_5_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE143944_2_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.27859
MRPS11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73279
ZNF511	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66951
NDUFAF7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52454
GSE182680,GSE182683_5_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE205976,GSE205978_1_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIM36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65407
FRA10AC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62106
RNF13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57431
NPIPB11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.12422
B3GAT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1507
PIANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8479
NHEJ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5328
GSE140997_4_v_3_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZIC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	61.0385
SPECC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.5405
MAZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32996
ARMC8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.77317
GSE202434,GSE202438_10_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ESYT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51625
GSE233679_14_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60521
BAZ2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73337
SH3PXD2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41263
GSE244710_3_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168473_0_v_1_isoniazid_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCAPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00736
PRPH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65945
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TCTN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.99602
ARRDC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.446
INTS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7287
PSMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.77599
INO80D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.8635
TRMT10C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47055
MKRN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.13672
ELMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47673
PUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17396
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAB11FIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46001
SCRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.88138
HNMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.53777
GSE166783_8_v_2_tp53_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RNASEK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70563
GSE140936,GSE140938_0_v_1_slfn11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE109565_12_v_11_glyphosate_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE184399_0_v_2_cnot1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SNF8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06896
PSMA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73528
PCMTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.66235
ALS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.0938
GSE233679_6_v_4_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE230263,GSE230265_5_v_1_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
YTHDF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.52297
GSE106661,GSE106665_0_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
NUFIP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.35494
RNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52634
APLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95556
EPS15L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85218
PIGA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78843
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE172494_3_v_1_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12856
ZW10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.23988
OSGIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78331
ZNF70	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70418
INSM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4542
ASMTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.14155
GSE233679_6_v_11_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TDRD12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8184
TUBA1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.15339
GSE182680,GSE182683_5_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
FASTKD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03379
FTL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.74279
CDK7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.58298
GTEx Esophagus 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	1.0	6.15729
PJA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88565
NEPRO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1491
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
MTF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.64004
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CD24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59006
GSE221327_5_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZMIZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71363
LPP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06942
GSE160817_4_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MLST8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57193
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LDB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.48323
LSM7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80479
ZMYM6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33856
BUD23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62749
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KLF10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	139.923
GSE119978,GSE180930_6_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RORC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2602
EYA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5258
PKP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.66828
FLNB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40881
RPL35	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51663
ECHS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.13298
TOR1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.81921
FOXO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36879
TRIM52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85581
PPM1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.22435
ESPL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49004
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7445411-CPR-53-e12862-s006.xlsx-Sheet1-Supplementary_Table_S4_Gene_expression_profiling_of_NT-MSC_and_III-MSC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
MFSD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.11452
MGAT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.65239
GSE237053_1_v_0_comt_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168797_2_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE133763_0_v_1_chd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EML2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28329
GSE227592_10_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of regulated secretory pathway	GO Biological Process Annotations 2025	1.0	null
RORB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.2446
GFY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88334
AKT1S1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63538
GSE223893_1_v_10_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
PLEKHG6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15734
C17orf49	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20907
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TMEM184C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92719
WBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.47311
MCCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.64337
GET4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.27982
IGFBP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04107
MOAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28104
GPX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52893
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_3_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_8_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
NPEPPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85424
CBX7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87273
TM9SF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35645
SBNO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45307
POGZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27178
INTS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69022