association	dataset	threshold value	standardized value
breast cancer	GWASdb SNP-Disease Associations	1.0	0.873424
H3K27me3_cardiac mesoderm_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INSM1_Deficiency_GDS5066_272_mouse_Fetal pituitary glands from embryonic day 17.5	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04155
A549_MLN8054_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141962
neoplasm of the breast	GWASdb SNP-Phenotype Associations	1.0	0.766703
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9H5-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K58890106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12512
CSNK1E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00610804
Infralimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08308
Perturb_2483_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE164757,GSE164759_4_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bexarotene_homo sapiens_gpl96_gds2777	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0057
posteromedial cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15825
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE68156_0_v_1_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
snare binding	GO Molecular Function Annotations 2015	1.0	null
equilin-4659	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Syntrophin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.757
GTEX-QV44-2026-SM-2S1RD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19672
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830191
GTEX-XQ3S-0008-SM-4GIDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45948
CME1	DepMap CRISPR Gene Dependency	1.0	2.19585
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3835
GPR151_GALP	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07901
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31349
RARB-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
anterior olfactory area, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17026
BRD-K43611837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51872
arsenic trioxide_homo sapiens_gpl201_gse48441	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958034
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917535
GTEX-U3ZN-0008-SM-4DXTL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37336
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886969
Lomitapide	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.28
ABC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Dorsal peduncular area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13746
hel	HPA Cell Line Gene Expression Profiles	-1.0	-0.826749
Orbital area, medial part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17693
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AA-22-UI44_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20508
r9 portion of ambiguous motor nucleus (postmigratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50921
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81E-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-BatSRBD_72Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.6208
PAX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15447
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50133846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61727
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INCA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05727
NO11	DepMap CRISPR Gene Dependency	1.0	3.78142
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997809
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal ekg	GWASdb SNP-Phenotype Associations	1.0	0.614969
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-7973-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K94962273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35742
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83049611	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11476
BRD-K19540840_saracatinib_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP1	ChEA Transcription Factor Targets	1.0	null
BRD-K77108738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40338
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IS-01A-21R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vesicle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
A549_AC480_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154429
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4205_KO_Top1_SRP072888	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.13364
organelle membrane fusion	GO Biological Process Annotations 2015	1.0	null
nomifensine-7217	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
PPP1CA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00477727
PMC10823279-CAS-115-283-s001.xlsx-Table_S5-Table_S5_List_of_188_genes_particularly_up-regulated_by_AR_in_AILNCaP14_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135030_11_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CAL33	CCLE Cell Line Gene CNV Profiles	1.0	1.40517
RANBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.25046
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
lateral part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.57506
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07575
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171352_2_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Mobilized_CD34_Primary_Cells_Female	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.64285
glutamatergic synapse	GO Cellular Component Annotations 2025	1.0	null
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.876577
Esophagus - Muscularis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.783195
BRD-K71339292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39339
NIF3L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65679
Brain Lower Grade Glioma_LGG_TCGA-DU-6393-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-2W-A8YY-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC11588066-pnas.2410331121.sapp.pdf-63-BPTF_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Preoptic area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.171
embryonic structure	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052285
BRD-K91459693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59479
BRD-K79404599_HY-10342_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
JAGN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27444
BRD-K52037352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03432
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.867229
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Weight Loss	CTD Gene-Disease Associations	1.0	1.13075
tinidazole-3430	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A19500257_geldanamycin_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EE-03-SG02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.20614
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37908
cortisone-7416	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_Streptozotocin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172336
GSE124471,GSE124488_1_v_0_lats1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MP-A4SW-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5875-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.064011
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07919
KP1N	DepMap CRISPR Gene Dependency	1.0	2.98329
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28261
BRD-K49328571_dasatinib_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02787
BRD-K42918627_GSK-2126458_LNCAP_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC10679662-mmc3.xlsx-NC-D5-ZEB2-Mutant-Downregulated-Gene_Symbol_ZEB2	Rummagene Transcription Factor Associations 2026	1.0	null
Crus II, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.10739
TEAD4	ChEA Transcription Factor Targets	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
MARCKS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00550732
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-SX-A7SR-01A-12R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_4159_KO_Mir137_SRP072457	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.78157
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.919201
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28281
pyramidal layer of IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07713
BCB000039-7510	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06704
brain ventricle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.161486
Kidney Chromophobe_KICH_TCGA-KM-8443-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TOP2B_drug inhibition_GSE1417_341_human_HeLa	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51395
CHEMBL1348080	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.37
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
neurotransmitter secretion	GO Biological Process Annotations 2015	1.0	null
A549_Dasatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131967
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSE-0011-R2A-SM-3P5ZL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28002
BICR 31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.987514
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K30038014	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09269
zona incerta	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.850422
establishment of synaptic vesicle localization	GO Biological Process Annotations 2015	1.0	null
PGR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00459203
GTEX-X4XY-0008-SM-46MVL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941339
A549_Sirtinol_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149174
muscle	GTEx Tissue Gene Expression Profiles	-1.0	-1.72248
P53_DN.V2	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
abnormal glucose homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.21137
Prestwick-857-3355	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
trimethoprim-3678	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TFAP2E	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.8632
paraventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.288158
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37278
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA2	ENCODE Transcription Factor Targets	1.0	null
BRD-K02927989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44956
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
single-organism localization	GO Biological Process Annotations 2015	1.0	null
BRD-K10385824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.13238
cellular component organization	GO Biological Process Annotations 2015	1.0	null
OAZ1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00399269
Posterior parietal association areas, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0587
GTEX-QDVJ-0008-SM-48U2E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
KB-78-BE93_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.28084
BRD-K74103290	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20139
A549_Rucaparib_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167818
BE-79-QU25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239398
HC-01-FD24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218828
AKT1_knockdown_43_GSE12291	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.89034
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17054
inner CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00757
IX, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07812
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.882477
PRKD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0053531
meclofenamic acid-7280	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
probucol-4666	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DIPK1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00385487
Postsynaptic cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.559
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A2LS-01A-22R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K42449328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2333
Perirhinal cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
triamterene-7307	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CEBPB-26923725-CHIP-SEQ-MACROPHAGESS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.9427
intrinsic component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.127391
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.963318
GSE114013,GSE114014_1_v_4_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate-hillock-club cell of prostate epithelium	Tabula Sapiens Gene-Cell Associations	1.0	1.26994
GSE128730_7_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
renal glomerular capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.316951
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE121319_1_v_2_gprc5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE161800_0_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSK126	DeepCoverMOA Drug Mechanisms of Action	-1.0	-3.02
Perturb_16522_KD_ASXL3_SRP247927	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Lung squamous cell carcinoma_LUSC_TCGA-37-5819-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ventral striatum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.203
SNU308	DepMap CRISPR Gene Dependency	1.0	8.0627
GSE146074_1_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.539519
MEF2C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.1326
Pheochromocytoma and Paraganglioma_PCPG_TCGA-P8-A6RX-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K72066653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13566
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-0.90266
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95698
FOSL1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LY-294002-6998	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AP-2rep	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF7	ENCODE Transcription Factor Targets	1.0	null
GSE206729_5_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K89650689	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04943
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3849
BRD-K56761719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26595
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.763211
GTEX-RU72-0008-SM-46MV8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975398
BRD-A18328003_GDC-0980_HCC515_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
ovary	GTEx Tissue Gene Expression Profiles	-1.0	-0.880601
BRD-K11516621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10666
BRD-K03602135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47146
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.952447
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.911947
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_7_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCL2L11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09121
PMC10238838-mmc4.pdf-132-STAT6_STAT6	Rummagene Transcription Factor Associations 2026	1.0	null
MYOG_myocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
letrozole-7336	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7742_KD_NOLC1_SRP316009	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87859
GSE210388_2_v_0_ror2_human	RummaGEO Gene Perturbation Signatures	1.0	null
r10 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.57394
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1118_KD_SENP6_SRP328207	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.60598
BRD-K28470988_L-690,330_RKO_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cortical amygdalar area, posterior part, lateral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44182
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UJMC-1826-SM-3GADT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01289
intermediate stratum of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.57184
benzathine benzylpenicillin-4022	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3911	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4338-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
allantoin-1800	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of calcium ion-dependent exocytosis	GO Biological Process Annotations 2015	1.0	null
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146982_7_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-POMQ-0008-SM-48TE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39243
BRD-K42918627_GSK-2126458_SKBR3_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Accessory olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.128
GTEX-N7MT-0011-R8a-SM-2I5GU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04992
BRD-K59317601_INK-128_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
iopamidol-7189	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K37956279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34049
GSE148066,GSE157787_9_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE109140_0_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K52424224	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33897
DE-69-QQ25_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257524
brain_3b	HPA Tissue Sample Gene Expression Profiles	1.0	1.36896
16,16-dimethylprostaglandin E2-6592	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
metal ion binding	GO Molecular Function Annotations 2023	1.0	null
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67874
membrane fusion	GO Biological Process Annotations 2015	1.0	null
EGR3_01_212	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.89941
QF-71-QI30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.748484
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49772
PMC11058205-42003_2024_6202_MOESM6_ESM.xlsx-Data3a_DirectGene_CEBPA-Data3a_Genes_directly_regulated_by_CEBPA_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
SELENOI	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00518822
Anterior olfactory nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04386
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LTE2_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
H3K9ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31905
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73849129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01186
organelle organization	GO Biological Process Annotations 2015	1.0	null
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Synucleinopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.011
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.859115
cellular process	GO Biological Process Annotations 2015	1.0	null
GSE128730_3_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164529_0_v_2_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
Iloprost	DeepCoverMOA Drug Mechanisms of Action	1.0	1.97
GSE240027,GSE240030_1_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB32	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00515499
GSE174701_5_v_8_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
abnormality of cholesterol metabolism	GWASdb SNP-Phenotype Associations	1.0	1.16985
valproic acid-347	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TMF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00534663
disease	GWASdb SNP-Disease Associations	1.0	0.083914
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7736-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233679_5_v_15_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
outer CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.2187
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K94012289_OSI-027_MCF10A_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PANC1	BioGPS Cell Line Gene Expression Profiles	1.0	1.43209
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN012_HEPG2_24H:G22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08896
GTEX-X585-0011-R2B-SM-46MVF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42664
short tibia	MGI Mouse Phenotype Associations 2023	1.0	null
BRD-K77578964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.37509
GTEX-QVJO-0011-R1A-SM-2S1QI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09391
SNG-M	GDSC Cell Line Gene Expression Profiles	-1.0	-1.57
periventricular stratum of r4Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3238
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42836
secretion	GO Biological Process Annotations 2015	1.0	null
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66051
parkinsonism	GWASdb SNP-Phenotype Associations	1.0	0.684265
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUDT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13477
znf217_22593193_mda_mb_231_gof_human_gpl570_gse35511	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.028274
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
QE-79-XO29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.483505
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TEN	CCLE Cell Line Gene CNV Profiles	1.0	1.59028
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.64414
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3443-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.884562
GTEX-U8T8-1426-SM-3DB9H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
Cortical amygdalar area, posterior part, medial zone, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38216
H3K27me3_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126345_0_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-3691-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
AC-84-QG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.553916
membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IT-01A-31R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K34937870	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33006
calcium- and calmodulin-dependent protein kinase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.136
GSE150049_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8507136-12935_2021_2224_MOESM5_ESM.xlsx-CREB1_upregulated_RRHO_list-RRHO_concordant_degree_CREB1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
L363	DepMap CRISPR Gene Dependency	1.0	5.06993
PAX5	ENCODE Transcription Factor Targets	1.0	null
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22785
HNF1B_OE_GDS1499_253_human_HEK293 embryonic kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of r2Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25863
decitabine-920	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_2492_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
U2AF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1521
superficial stratum of m1B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00795
ESR1_ECC-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
locus ceruleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.432991
NME4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00646319
valproic acid-6934	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pipenzolate bromide-4484	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
diazoxide-7168	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Postsynaptic specialization membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.683
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A5-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Smoking	DisGeNET Gene-Phenotype Associations	1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6938365-pone.0226733.s020.txt--CTCF_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MU-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0056
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03296
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6937-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9618568-41467_2022_34255_MOESM6_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
letrozole-4240	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20B-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92440102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.7022
ED-05-KX67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220504
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EO-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.807611
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.22045
BRD-K49865102_PD-0325901_HEPG2_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-A45498368_WYE-125132_LNCAP_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Postsynaptic Golgi apparatus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.265
Fetal Lung	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.32977
NCIH209	CCLE Cell Line Gene Expression Profiles	1.0	1.3688
anterior (rostral) cingulate (medial prefrontal) cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.84205
Perturb_10655_OE_Ar_SRP123610	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
lateral hypothalamic area, anterior part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.19523
GSE229580_2_v_1_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
kidney	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.129154
BRD-K07624584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03436
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE139987_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE125014_1_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10086
A549_Mocetinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0206135
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16151
GTEX-X4XX-0008-SM-46MVK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
podocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.351856
GSE138633_2_v_0_bag3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.861015
BRD-K67602895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18219
ZNF512	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00652402
HEC1B	DepMap CRISPR Gene Dependency	1.0	2.65232
ceftazidime-5473	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE216273,GSE216292_0_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2110	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824756
GSE192663_1_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K67868012_PI-103_MCF10A_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KMS12BM	CCLE Cell Line Gene CNV Profiles	1.0	1.63846
H3K4me1_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-SN8G-0008-SM-4DM4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15545
BRD-K21423945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43003
ivermectin-2051	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.829277
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.933206
p3 portion of the substantia nigra pars reticulata	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11471
BC-74-QN56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306534
PRKDC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00673939
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.938562
SW684	GDSC Cell Line Gene Expression Profiles	-1.0	-2.09332
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68065987_MK-2206_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K78344913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.132
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03434
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.877666
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.234515
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855379
pheochromocytoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.194002
CRCGN015_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64813
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ4-0008-SM-48TE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3456
CRCGN012_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0737
GSE211425_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2BC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01828
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71591
JF-96-HH81_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.302777
5182598-976	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
18270326-Table1	GeneSigDB Published Gene Signatures	1.0	null
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.430299
MCM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0543
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
glucose metabolism disease	GWASdb SNP-Disease Associations	1.0	0.280495
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.19975
intermediate stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40706
UM-UC-3	GDSC Cell Line Gene Expression Profiles	1.0	1.43036
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AU-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Field CA1, stratum pyramidale	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02405
intrinsic component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.101693
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Penis_Foreskin_Melanocyte_Primary_Cells_skin03	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.06196
renal distal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.413151
GSE176008_0_v_2_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIGLEC12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00599284
abnormality of the lung	GWASdb SNP-Phenotype Associations	1.0	0.126083
BF-49-QA17_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250044
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of erythrocytes	GWASdb SNP-Phenotype Associations	1.0	0.258057
Prostate adenocarcinoma_PRAD_TCGA-HC-7747-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K27me3_iPS-20b	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IL-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Azacitidine_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0183677
Brain Lower Grade Glioma_LGG_TCGA-DU-7018-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
troglitazone-6949	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A549_Resveratrol_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0298129
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AMG 487	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
BRD-K78431006_HY-50878_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LC-12-VN85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.38772
GSE114284_2_v_0_irf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
JEKO1	CCLE Cell Line Gene Expression Profiles	1.0	2.29985
HDAC11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0045252
SSBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76278
PMC10785552-13059_2023_3149_MOESM7_ESM.xlsx-RNAseq_HOXA9_rescue-Table_S6_The_DEGs_in_in_RBM5_KO_cells_with_HOXA9_overexpression_relative_to_RBM5_KO_control_HOXA9	Rummagene Transcription Factor Associations 2026	1.0	null
GSE198826,GSE198911_1_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045123
EA-84-SC49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208668
DKMG	CCLE Cell Line Gene CNV Profiles	-1.0	-2.80097
nrk cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.199557
Exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CRCGN017_MCF10A.WT.HP_24H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00437
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.583397
CORL279	DepMap CRISPR Gene Dependency	1.0	5.92269
SUCLG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00632507
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38806
GSE130401_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56431
CRCGN015_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.83504
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17798
CRCGN016_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.66288
DPP9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00678938
BRD-K34720817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19166
Brain Lower Grade Glioma_LGG_TCGA-VV-A829-01A-21R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Barasertib_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0151632
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1463	DepMap CRISPR Gene Dependency	1.0	2.94193
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222841
moroxydine-1527	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ANO6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09543
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2126	CCLE Cell Line Gene Expression Profiles	1.0	1.3883
cyproheptadine-1521	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
response to calcium ion	GO Biological Process Annotations 2023	1.0	null
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.950599
K5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cytoplasmic part	GO Cellular Component Annotations 2015	1.0	null
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.827302
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917566
AB-30-CR11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.505901
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31011
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12477
Connecting tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
BRD-K54123736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03457
lung_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.866527
CSGALNACT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00664292
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.970811
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16569
BRD-A45498368_WYE-125132_LNCAP_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AFD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00808719
SP4	ENCODE Transcription Factor Targets	1.0	null
GSE193258,GSE193259_9_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
phenylpropanolamine-6699	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
octopamine-5050	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE144231_4_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.928033
BRD-K84987553_MDM2 Inhibitor_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LIM1215	COSMIC Cell Line Gene Mutation Profiles	1.0	null
WC-16-IR43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.547447
Serotonergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.881
olivary pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00588
PMC8143797-elife-62857-fig3-data2.xlsx-DEgenes_SW872_CAMTA1_vs_subEV-Gene_CAMTA1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K06550516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21599
WC-09-GD62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.908648
DUSP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00348483
GTEX-S4P3-0008-SM-3NM8R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
BRD-K31834149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62203
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nephron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.166975
amygdaloid complex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.847623
BRD-K26459891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23285
layer 3 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51412
RAD21_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RD-50-EO07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.766114
GTEX-T6MN-0008-SM-4DM7H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.252261
TIE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09164
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.951335
BRD-K08966355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03717
Perturb_2480_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
regulation of dendrite extension	GO Biological Process Annotations 2023	1.0	null
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10699
KLHDC8B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00600239
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11448
GSE126345_9_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
substrates	GeneRIF Biological Term Annotations	1.0	null
glomerular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.329361
Subiculum, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00691
Sarcoma_SARC_TCGA-DX-A2IZ-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MRTO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57102
SA-32-CC58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.466613
GTEX-P4QT-1626-SM-2S1NP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993777
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02936
GSE162892_3_v_0_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
induseum griseum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0783
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178532_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K03467766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18519
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850635
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69716
GSE51684,GSE51741_2_v_4_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.68883
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49865102_PD-0325901_HT29_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ion binding	GO Molecular Function Annotations 2015	1.0	null
BRD-K10670311_Sulfasalazine_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MEL18_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.991749
BRD-K78809123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21228
ABL1_mutant_24_GDS4046	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.35967
DNMT3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00362506
bromopride	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.93958
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17874
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.524592
metencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.335968
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
WC-09-GD62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222926
BRD-K87658102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03176
VIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18432
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
CCDC85B	Hub Proteins Protein-Protein Interactions	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00529764
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26923
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73844
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331919
CTCF_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DB-24-CQ08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230632
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A_48H:M22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.08561
PMC9104602__F5	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-WFG7-1826-SM-3GIL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27466
YWHAB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14046
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0011-R1A-SM-2HMJI	GTEx Tissue Sample Gene Expression Profiles	1.0	2.3408
GSE135030_11_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE126463_6_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58334
BRD-K21025364_NVP-TAE226_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_Capecitabine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0201004
ventral posterolateral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21841
sertaconazole-4475	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6TY-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12275
membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042955
FLNB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00547567
UCN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00445404
breast carcinoma	GWASdb SNP-Phenotype Associations	1.0	0.766703
POU2F2	ENCODE Transcription Factor Targets	1.0	null
TAL1	MotifMap Predicted Transcription Factor Targets	1.0	null
EB-3	GDSC Cell Line Gene Expression Profiles	1.0	1.93285
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.307586
EE-18-HW72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.412484
TE4	DepMap CRISPR Gene Dependency	1.0	6.76262
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193351_4_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PAK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0051506
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEG4-0526-SM-48TZD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983418
BRD-K87558616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4184
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.881777
GSE71468,GSE76476_0_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN017_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.5131
PMC12640707-NIHMS2124006-supplement-Supplemental_tables.xlsx-Supplemental_Table_S4-Supplemental_Table_S4_Genes_commonly_upregulated_in_both_clones_of_ZFX-depleted_HEK293T_cells_in_Ni_et_al_2020_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
HES5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6225
CHD4-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7786-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HQ-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38979
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fusiform gyrus, right, bank of cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.957162
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857122
positive regulation of dendrite extension	GO Biological Process Annotations 2025	1.0	null
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.572569
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57577
GSE212312_2_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K29415052_NVP-BGT226_HT29_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K05796780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1841
GSE174701_1_v_0_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCBP2AS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13708
Lung squamous cell carcinoma_LUSC_TCGA-77-8143-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CP2/LBP-1c/LSF	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952845
Lung squamous cell carcinoma_LUSC_TCGA-22-1002-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93747373_HG-5-113-01_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prenatal Exposure Delayed Effects	CTD Gene-Disease Associations	1.0	1.11843
C2 domain	InterPro Predicted Protein Domain Annotations	1.0	null
Neurosphere_Cultured_Cells_Ganglionic_Eminence_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.16843
PHKG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00542849
membrane	GO Cellular Component Annotations 2015	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55F-1726-SM-2TF4R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848228
hsa-miR-642b	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.1361
PMC12171002-jcav16p2578s1.pdf-2-PPARG_PPARG	Rummagene Transcription Factor Associations 2026	1.0	null
MTRES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05588
BRD-K10684867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21785
PMC7455079-jciinsight-5-140380-s227.xlsx-Supp_Table_9-Supplemental_Table_9_Limma_DE_Analysis_of_HC_AA_to_EA_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
BRD-K16933266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27571
BRD-K67856917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26518
A549_G007-LK_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.023328
BRD-K91866516	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65898
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95943192	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1739
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29W-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE79663_2_v_0_tcf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WZTO-0011-R1B-SM-3NMAR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15011
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Dorsal raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Benign prostatic hyperplasia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.729
H3K4me1_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
isthmic portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18947
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	3.21942
ventrolateral prefrontal cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.980457
CTCF_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123105,GSE124556_0_v_2_pcf11_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01719
NINL	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
CF-50-QK79_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.271918
GSE115364_0_v_1_idh3a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Immature dendritic cell_Stomach_Human	CellMarker Gene-Cell Type Associations	1.0	null
TRAF4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00555211
RING1B-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE101336_1_v_0_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-O5YV-0008-SM-4E3HP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A6UF-01A-23R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K46291400	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68652
Brain Lower Grade Glioma_LGG_TCGA-DU-5874-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12187
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A3ZE-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DUSP11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00447221
JB-14-TF61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222407
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SIU8-0008-SM-4BRUC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16366
CD19+_BCells(neg._sel.)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.879979
SH3YL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41044
short insular gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.962753
DMS454	CCLE Cell Line Gene CNV Profiles	1.0	1.79082
GSE201239_6_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ACKR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00539711
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295705
RPMI-8866	GDSC Cell Line Gene Expression Profiles	1.0	1.70437
Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FYB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00507414
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.964284
OSC19	DepMap CRISPR Gene Dependency	1.0	2.42333
SP in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15774
pancreas	HPA Tissue Protein Expression Profiles	1.0	0.777364
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5284
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_14_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.943272
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39785
Secretory granule membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.884
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06024
H3K27me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05546
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7100-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LS-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Infralimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0951
BRD-K81439435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19352
Substantia nigra, reticular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02405
FAM167B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6382
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.962042
AC-98-QW77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257976
IL1RN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00725222
BRD-K67591072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04845
BRD-K63778487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76052
GSE133505_5_v_4_myf6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PD-70-VS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.830546
FAAH2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00702616
BRD-K39592958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33717
econazole-7427	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cerebellum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.33965
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.36419
benzethonium chloride-7207	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_2-Methoxyestradiol_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142641
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
synaptic vesicle	GO Cellular Component Annotations 2015	1.0	null
BRD-K31608682	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15133
A549_KW-2449_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129688
18787218-tableS1	GeneSigDB Published Gene Signatures	1.0	null
abnormality of the globe	GWASdb SNP-Phenotype Associations	1.0	0.116293
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NR3C2-34362910-WISTARRAT-HIPPOCAMPUS	ChEA Transcription Factor Targets 2022	1.0	null
acquired metabolic disease	GWASdb SNP-Disease Associations	1.0	0.157483
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.25789
SOX10	MotifMap Predicted Transcription Factor Targets	1.0	null
CCDC86	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00473724
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Basolateral amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38941
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LC-12-VN85_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.354125
GTEX-X4EO-0526-SM-3P5Z3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0552
temporal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.901176
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2932-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.911282
clathrin-coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CTCF_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.308767
brain	GTEx Tissue Gene Expression Profiles	1.0	0.887759
REST-18959480-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-DLX3_EVT-Gene_Symbol_DLX3	Rummagene Transcription Factor Associations 2026	1.0	null
JF-30-FW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218881
SK-MEL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.89811
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33106
artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060209
metyrapone-4606	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46521
CHD1	ENCODE Transcription Factor Targets	1.0	null
A549_Tazemetostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0193364
EE-98-PF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269377
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04701
BRD-K69932463_AZD8055_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mRNA_GATA3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02787
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE192663_3_v_2_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3419-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
area	GeneRIF Biological Term Annotations	1.0	null
GTEX-RU72-1426-SM-46MUF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869891
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.3731
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.62784
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7409-01A-31R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AE-39-DG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204967
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41311
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_x_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.13827
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
sense organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.057396
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908889
hypothalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.271952
A549_Ramelteon_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.017893
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE57871_6_v_9_vorinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_13039_KD_Tardbp_SRP314028	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-13.0409
ischemia	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.260891
PUM3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00596732
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66624
GSE102505_6_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A45498368_WYE-125132_MCF10A_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
short tibia	IMPC Knockout Mouse Phenotypes	1.0	null
BRD-K61776140_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMYND8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75112
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
A549_Daphnetin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144482
ZNF384	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	293.182
BRD-A19500257_geldanamycin_MCF7_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
6-benzylaminopurine-3726	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Visual cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.035
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD51C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00440409
BRD-K67278762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22165
decreased pulmonary ventilation	IMPC Knockout Mouse Phenotypes	1.0	null
BRD-K95048194	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.53351
phospholipid binding	GO Molecular Function Annotations 2015	1.0	null
AADAT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00569724
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	1.37169
estradiol_mus musculus_gpl4134_gse23241	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
icSARA deltaORF6_7Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.43517
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.4446
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.938009
doxycycline-5838	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.25499
HC-74-HM63_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229796
RDH11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00423465
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
flunixin-3713	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K57441129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17151
GSE135030_8_v_2_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01762
pyramidal layer of taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04498
FOXE1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	99.5223
PMC4467436-oncotarget-06-6267-s002.xlsx-140527_cd44Cutoff_txt-OLIG2-M_OLIG2	Rummagene Transcription Factor Associations 2026	1.0	null
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.253
Lung squamous cell carcinoma_LUSC_TCGA-63-A5MY-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE57397,GSE57399_1_v_0_fbxw7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FF-86-NH56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.647961
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33602
hilus of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43205
A549_G007-LK_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0203354
A549_Aurora A Inhibitor I_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0217689
prostate_4b	HPA Tissue Sample Gene Expression Profiles	1.0	1.06462
Presynaptic periactive zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.628
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K76748254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5307
SAP30	ENCODE Transcription Factor Targets	1.0	null
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.894939
EC-62-OE64_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.96367
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4699-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CILP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00527173
abnormality of central motor function	GWASdb SNP-Phenotype Associations	1.0	0.684265
KGN	GDSC Cell Line Gene Expression Profiles	-1.0	-1.65537
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966929
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K03568209_CID 755673_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
21205295-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GD-46-OD81_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.34919
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1081-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.075709
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-HL-60-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_HL-60_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
CB-55-AK76_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264366
GSE197117_0_v_1_kdm6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
carbinoxamine-6786	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29077
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.33619
Sarcoma_SARC_TCGA-RN-A68Q-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.901708
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880352
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66283
EA-18-FP00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.48547
NCIH2141	CCLE Cell Line Gene CNV Profiles	1.0	1.74126
CA-72-JV60_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204988
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1152
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XV7Q-0008-SM-4BRWL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01037
NFYA	ENCODE Transcription Factor Targets	1.0	null
GTEX-S4Q7-0008-SM-3NM8A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
SPI1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_2488_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.709867
respiratory system cancer	GWASdb SNP-Disease Associations	1.0	0.245523
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hydroflumethiazide-1687	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Crop	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.738
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38844
ONECUT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	140.64
GSE135030_3_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H510A	GDSC Cell Line Gene Expression Profiles	1.0	2.50547
bronchus	HPA Tissue Protein Expression Profiles	1.0	0.777364
GTEX-XLM4-0011-R2B-SM-4AT5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49289
GSE87404,GSE87812_1_v_0_hoxa9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
ABCA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00697702
BRD-K10580455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13054
MYOD1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
halcinonide-3680	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE186647,GSE217287_1_v_3_hnrnpc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XUW1-0126-SM-4BOOQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.861693
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARFGEF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43132
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66661
diphenhydramine-1830	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_1397_KO_Psen1_SRP220423	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE142210_9_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CP-944629-7502	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62108
BRD-K10705233_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE190322,GSE190324_3_v_4_rbm4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-11_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
A549_MC1568_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0199021
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42805893_HG-14-8-02_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K89687904_PKCbeta inhibitor_LOVO_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE171486_4_v_6_ddx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
M040416	DepMap CRISPR Gene Dependency	1.0	6.31241
QE-79-XO29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264133
NPIPA8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58991
BRD-K43389698_BMS-387032_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GB-73-QS80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.410026
BRD-K49865102_PD-0325901_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.42118
GTEX-TML8-0008-SM-4DXUI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35742
BRD-K43639523	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07058
Dapiprazole	DeepCoverMOA Drug Mechanisms of Action	1.0	0.4
HEL	DepMap CRISPR Gene Dependency	1.0	2.56886
PMC11196699-41598_2024_61762_MOESM1_ESM.xls-Normal_v_Advanced-PRDM16_PRDM16	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12555
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42247
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K39074860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2606
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.53061
cellular response to calcium ion	GO Biological Process Annotations 2023	1.0	null
SOX9-24532713-HFSC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_EED226_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0124923
ARID3A	ENCODE Transcription Factor Targets	1.0	null
GSE174701_1_v_7_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE167324_1_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AH-0008-SM-48U2J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.990389
CE-18-AP15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246091
PMC3435504-msb201237-s2.xls-Supp_Table_4c-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-W5WG-0008-SM-4KL25	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
SELL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00520396
A549_XAV-939_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142529
regulation of secretion by cell	GO Biological Process Annotations 2015	1.0	null
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.41379
GTEX-R55D-0008-SM-48FEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14268
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FM-8000-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RASGRP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00489436
CRCGN016_MCF10A.WT.HP_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.00092
Taenia tecta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16226
A549_Pirarubicin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.011136
GSE232631_5_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
stomach	HPA Tissue Protein Expression Profiles	1.0	0.777364
GTEX-QEL4-0008-SM-447AZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10643
PARP	MotifMap Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
ZBTB14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63095
BRD-A04231641	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23028
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE174701_4_v_3_maml3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Rhomboid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.788
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.55474
NCIH1105	CCLE Cell Line Gene Expression Profiles	1.0	1.69034
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
A549_MC1568_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0262474
ZPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.139
cerebellar cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28633
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-EGR1_DC_ChIP-seq_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
ventral linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08342
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51237
BRD-K55598155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00507
GTEX-OIZG-0008-SM-4E3J2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55511
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28249
VCAP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.69764
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20858
GTEX-XBEC-1526-SM-4AT68	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932838
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Differentially_Expressed_Genes_DEGs_of_OE-HIF1A_vs_OE-GAL4_Veh_in_Bulk_RNA-seq_Data_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06117861	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15517
external segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.832439
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-7138-01A-41R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K49328571_dasatinib_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-3923-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_8_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KPNYN	DepMap CRISPR Gene Dependency	1.0	3.34662
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CD4_Memory_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.870329
BRD-K69408624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31322
CARM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00459813
GSE157609,GSE158123_0_v_1_ifi16_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K82764092	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02464
PLXNA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00659298
NCIH854	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58379
BRD-K87712055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24309
GTEX-S7SE-0011-R2A-SM-2XCDC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914062
GTEX-R55F-1526-SM-2TF4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873789
RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.3892
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.521297
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.46321
Lung adenocarcinoma_LUAD_TCGA-95-7947-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MBD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00486098
PHA-00816795-7072	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EZH2_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMR6-0008-SM-447AV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09227
GTEX-TSE9-0011-R1A-SM-3DB7E	GTEx Tissue Sample Gene Expression Profiles	1.0	0.876185
NANOG-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.218613
ID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14776
salsolidin-4810	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885762
glycopyrronium bromide-4709	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PITX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5356
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.714575
Brain Lower Grade Glioma_LGG_TCGA-DH-5144-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Medial septum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.963
inner CP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.47677
BRD-K40175214_torin-1_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57080016_selumetinib_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
caudate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36223
H3K27me3_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Joubert syndrome 20	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.554
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.917234
hippocampus (hippocampal formation)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16513
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K99252563_QL-XII-47_MCF7_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6012-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic membrane-bounded vesicle	GO Cellular Component Annotations 2015	1.0	null
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06617
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A1KZ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46651
TEAD4-22529382-TROPHECTODERM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K20722478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17278
SLC12A9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31559
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.457094
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3C1-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACMSD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00669
CTCF_HEK293_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Claustrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.631
BRD-K02708799_GSK-1059615_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
llc-pk1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.597666
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_mononuclear cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Linear nucleus of the medulla	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04312
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	81.5087
PMC10274745-media-4.xlsx-S3A-Table_S3_Reanalysis_of_publicly_available_data_to_identify_AR_and_ER_direct_target_genes_related_to_Figure_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
cytoplasmic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CTCF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRR14L	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00445008
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16151
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.394173
gallbladder	HPA Tissue Protein Expression Profiles	1.0	0.777364
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CC-44-MG29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.43675
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10434
atherosclerosis	GWASdb SNP-Disease Associations	1.0	1.17489
TE5	DepMap CRISPR Gene Dependency	1.0	3.69791
GSE123825_0_v_3_glud1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
harmaline-4968	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOXA1-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
RPL22L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7235
GSE90710_1_v_0_med13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16819
BRD-K42436189_AZ20_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
UBE2K	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16879
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ES-I3 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.27679
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A42Q-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9038526-mmc1.xlsx-healthy_ctr_vs_LPS-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
THRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.1478
BRD-K99818283_PIK-90_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LIPT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0048509
ADAM10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00510849
BC-00-YH62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230341
regulation of vesicle-mediated transport	GO Biological Process Annotations 2015	1.0	null
AF-99-HA02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.368079
PMC10246722-pwac062_suppl_supplementary_table_s5.xlsx-sg-HIF1A_vs_sg-GAL4-Unnamed_1_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.17123
Medial mammillary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.58
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CDK9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0050432
GSE167474_2_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GMPPB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00555826
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Pituitary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.1419
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE167474_1_v_3_naa40_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NOMO1	DepMap CRISPR Gene Dependency	1.0	2.74271
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16151
EZH2-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
organ system cancer	GWASdb SNP-Disease Associations	1.0	0.066685
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.57132
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29495
dorsolateral prefrontal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.83
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23642
BRD-K65245206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3512
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.938166
Brain Lower Grade Glioma_LGG_TCGA-DU-6404-02A-21R-A36H-07,TCGA-DU-6404-02B-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
neoplasm of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.26448
BRD-K46811723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34873
GTEX-WHSE-0011-R4A-SM-3P5ZN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0837
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23656
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K76461283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35267
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
establishment of vesicle localization	GO Biological Process Annotations 2015	1.0	null
BRD-K99300752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11718
GSE147876,GSE147877_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-8258-11A-01R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K91820608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75052
hippocampus (hippocampal formation)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.924661
ALMS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00637922
LP1	DepMap CRISPR Gene Dependency	1.0	2.40313
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.555159
PES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10055
hippocampus (hippocampal formation)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16707
NCIH2141	CCLE Cell Line Gene Expression Profiles	1.0	1.55321
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.958679
BRD-A45498368_WYE-125132_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SL-01B-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BF-02-AC35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.248922
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.608785
A549_AG-490_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163575
MYOD1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC2270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Mianserin	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
A549_CYC116_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155255
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874661
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCFAP2C-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K28472865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19806
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24436
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF257	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	59.0301
Perturb_8934_KO_EZH2_SRP250286	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.849801
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K58290803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51195
hippocampus (hippocampal formation)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24774
molecular layer of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14264
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04883
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.583621
A549_SGI-1776 free base_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128619
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.29722
PMC5390115-mmc3.xlsx-DE_Lists_Exp_2-H1-EC2_3-fold_TCF15	Rummagene Transcription Factor Associations 2026	1.0	null
butirosin-6779	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
NCIH2347	CCLE Cell Line Gene CNV Profiles	-1.0	-1.91425
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
AOB, mitral cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00065
WC-09-GD62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.630462
HDAC2	ENCODE Transcription Factor Targets	1.0	null
GSE182770,GSE182784_0_v_1_chd2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
membrane	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
IDUA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00586741
regulation of biological quality	GO Biological Process Annotations 2015	1.0	null
GTEX-XAJ8-1026-SM-47JY9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19676
GTEX-RTLS-0008-SM-48FET	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34434
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IFITM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00608029
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.01399
Synaptotagmin	InterPro Predicted Protein Domain Annotations	1.0	null
GTEX-R55G-0008-SM-48FEX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835063
NCIH510	CCLE Cell Line Gene Expression Profiles	1.0	3.40795
BRD-K87872414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74461
Mesosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.834
A549_Bisindolylmaleimide IX_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0212945
PECAM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00907142
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.933464
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HD-29-PZ41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213704
Prostate adenocarcinoma_PRAD_TCGA-G9-7519-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
EZH2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BIRC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.2288
GSE202134_0_v_1_rbm39_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K02688026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48384
GSE197555_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.948802
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3374-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193258,GSE193259_2_v_1_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
periventricular stratum of r3Co	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02883
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A497-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K51153795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19232
NCIH146	CCLE Cell Line Gene Expression Profiles	1.0	1.42629
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN015_MCF10A_48H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.41799
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.828974
SLC39A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03445
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62976536	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48525
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07919
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.13194
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
basolateral amygdaloid nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43404
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.929106
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31879
BRD-K56405136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07792
GTEX-X62O-0008-SM-46MU5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3328-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72135530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12275
Conduct disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
GSE159678_4_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K21680192_mitoxantrone_MCF10A_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04596
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53901855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56945
16643655-1300GenesList	GeneSigDB Published Gene Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62202
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.1821
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053962
A549_SRT3025 HCl_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0123111
GNAT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00540952
BRD-K58220038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07454
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE154074_2_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Hypothalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.959752
BRD-K55479099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52533
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10572
Lung squamous cell carcinoma_LUSC_TCGA-60-2706-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
xylometazoline-7020	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EFO21	CCLE Cell Line Gene CNV Profiles	1.0	1.87586
propofol-5306	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GABRA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00630805
Dentate gyrus, granule cell layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55965
Rectum adenocarcinoma_READ_TCGA-G5-6572-02A-12R-1830-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCT5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35151
GTEX-Q2AI-1526-SM-3GIJ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13761
19204204-SupplementaryTable7	GeneSigDB Published Gene Signatures	1.0	null
paraterete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44371
GTEX-NL3H-0008-SM-4E3HU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44507
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-gene_id_y_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN015_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.456
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05987
ESR1	ENCODE Transcription Factor Targets	1.0	null
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976127
BRD-K06614664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89591
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane organization	GO Biological Process Annotations 2015	1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21631
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.862099
NRK-52E cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.649
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895739
PMC8212786-DataSheet_4.xlsx-CESC-ZBED3_ZBED3	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20526256_HG-14-10-04_HT29_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cardiovascular system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041328
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14004
caudal (posterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09103
PHOX2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	93.1486
BRD-K02708799_GSK-1059615_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH1793	CCLE Cell Line Gene CNV Profiles	-1.0	-1.60779
superficial stratum of PHyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.44563
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.503642
posterior (ventral) nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.29645
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6948-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE159678_4_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
voltage-gated sodium channel complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.045
DMS79	CCLE Cell Line Gene Expression Profiles	1.0	1.53719
CRCGN016_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.57605
basal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.254239
DMNB	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.3012
Parkinson Disease	DisGeNET Gene-Disease Associations	1.0	null
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07412
GSE207514,GSE207515_1_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE150669_2_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T5JC-0008-SM-4DM6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
BRD-K82667180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89494
AURKA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19315
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7737-11A-02R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
KASUMI1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05461
DHRS9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00493076
H3K27me3_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146074_10_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
substantia nigra compacta, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03614
ZBTB14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1812
GTEX-WHPG-0226-SM-3NMB9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824363
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.66096
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19B-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K38935430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01041
GSE249098_3_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128076_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.222
RAD21_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.4994
Formestane	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.35
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06639
Brain_Germinal_Matrix	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.959307
BRD-K10505056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.67087
famotidine-5011	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3440-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K43306617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6486
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.53871
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
exocytic vesicle	GO Cellular Component Annotations 2025	1.0	null
Perturb_18511_KD_UHRF1_SRP217518	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H9 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.652
C17orf80	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02384
proscillaridin-7340	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.37
nifedipine-1814	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A549_Lapatinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0246236
regulation of catecholamine secretion	GO Biological Process Annotations 2023	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
succinylcholine-chloride	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40481
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927025
BRD-K69932463_AZD-8055_LNCAP_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE227592_6_v_1_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041077
external granular (germinal) layer of upper rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15817
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.899782
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial (main) part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70945
GTEX-XGQ4-0008-SM-4AT3Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39926
GSE125011_0_v_2_cd83_human	RummaGEO Gene Perturbation Signatures	1.0	null
Apical dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.344
AC-74-ZA35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.650692
Perturb_2490_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
BRD-K49328571_dasatinib_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
A549_A-366_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0173755
RPL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39062
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.902167
abnormality of the head	GWASdb SNP-Phenotype Associations	1.0	0.115975
GSE247084,GSE247087_0_v_1_cdyl_human	RummaGEO Gene Perturbation Signatures	-1.0	null
INSM1_lack of the seven N-terminal amino acids_GDS5066_404_mouse_pituitary glands	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K92172862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53409
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
daunorubicin-7525	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.03938
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	2.26545
NCIH2073	CCLE Cell Line Gene CNV Profiles	1.0	1.96104
RBM25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40699
CRCGN015_MCF10A.TP53.M_24H:E24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21445
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE140651,GSE140653_2_v_4_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r4 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32525
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
FOSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.61635
GSE133764_2_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE218727_0_v_1_zkscan3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC2866657-pone.0010547.s001.xls-ERG-high-GENES_DOWNREGULATED_IN_ERGhigh_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
km3	HPA Cell Line Gene Expression Profiles	-1.0	-0.826749
Cerebral ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.644
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1-33576154-HUMAN-LUNG-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9653
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.916242
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.99981
ISG20	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00758841
BRD-K86293440	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36101
lynestrenol-6756	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34483
Tobacco Use Disorder	HuGE Navigator Gene-Phenotype Associations	1.0	null
interpeduncular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.32183
SMAD1-26771354-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
ATP1B2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00639959
ependymocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.206515
CRCGN015_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84358
GSE162892_3_v_2_isox_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K38273665	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32877
cardiovascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053864
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C75	DepMap CRISPR Gene Dependency	1.0	3.3259
GSE166315_1_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.12911
amylocaine-1491	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H630	COSMIC Cell Line Gene Mutation Profiles	1.0	null
calcium-dependent phospholipid binding	GO Molecular Function Annotations 2023	1.0	null
Prestwick-984-7323	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Minor Salivary Gland	GTEx Tissue Gene Expression Profiles 2023	1.0	1.20942
Pyrimethamine	DeepCoverMOA Drug Mechanisms of Action	1.0	0.21
positive regulation of developmental growth	GO Biological Process Annotations 2025	1.0	null
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262007
mantle zone of PcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75746
GTEX-SUCS-0008-SM-4DM53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35319
NCIH1836	DepMap CRISPR Gene Dependency	1.0	7.20892
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205730,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Ventral posterolateral nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42488
Prelimbic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.52
CRCGN008_HEPG2_24H:H13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5312
dorsolateral prefrontal cortex_4 mos_M_12890	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.84346
hsa-miR-574-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.969298
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	1.85313
hsa-miR-3646	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-XYKS-0008-SM-4BRW6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33569
doxycycline-3479	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spanning component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.246769
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231715
F36P	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33245
GSE171837_3_v_1_bortezomib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SE-15-AV21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296821
TMEM14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0817
PMC10238838-mmc1.pdf-28-STAT6_STAT6	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5629025-elife-27159-fig1-data1.xlsx-Direct_AR_target_genes-Control_only_down-regulated_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Autistic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.33
GSE81803,GSE81912_4_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SETDB1-19884255-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
acemetacin-7442	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE213996_1_v_0_fhl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
r9 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46729
GTEX-W5WG-1926-SM-4KKZK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00379
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SNU840	DepMap CRISPR Gene Dependency	1.0	4.02853
BRD-K49865102_PD-0325901_HT29_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11760944-41598_2025_86694_MOESM1_ESM.pdf-153-JDP2_JDP2	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Bisindolylmaleimide IX_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147461
BRD-K16485616_mocetinostat_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_Cimetidine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0162225
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
transporter activity	GO Molecular Function Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5365-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
l23	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.272
embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05336
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.16537
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of cardiovascular system physiology	GWASdb SNP-Phenotype Associations	1.0	0.084248
A549_RG108_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.017029
securinine-4493	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HOPX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00612882
CE-00-EK89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.200304
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MZ-A6I9-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60705
KCNA10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00607732
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DYRK2	Kinase Library Serine Threonine Kinome Atlas	1.0	null
ACHN	CCLE Cell Line Gene CNV Profiles	1.0	1.42142
abnormality of the eye	GWASdb SNP-Phenotype Associations	1.0	0.08525
NRF1	ENCODE Transcription Factor Targets	1.0	null
DA-10-GX45_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268212
BRD-A45498368_WYE-125132_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_Tazemetostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0220218
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19407
GSE133763_0_v_1_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TMED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43734
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
they	GeneRIF Biological Term Annotations	1.0	null
GTEX-TMMY-0008-SM-4DXU3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
BRD-K04269696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64305
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
BRD-K73789395_ZM 336372_SNGM_6.0_h_102.71_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R45C-0008-SM-48FF2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11917
TT	GDSC Cell Line Gene Expression Profiles	1.0	2.48493
H3K4me3_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K72894736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44281
abnormality of the fundus	GWASdb SNP-Phenotype Associations	1.0	0.194188
CRCGN015_MCF10A.TP53.M_24H:P14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0408
S-isopropylisothiourea	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04217
thalidomide-606	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
oral cleft	GWASdb SNP-Phenotype Associations	1.0	0.913571
RT112	DepMap CRISPR Gene Dependency	1.0	3.72028
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215918
MINPP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.43712
Perturb_4211_KO_Fmr1_SRP354984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.9547
CRCGN017_MCF10A.WT.HP_24H:E13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.8712
SMAD4-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.277
NCIH2342	CCLE Cell Line Gene Expression Profiles	1.0	1.45027
INSM1_KO_GDS5066_472_mouse_pituitary gland	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K90821428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94573
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.3281
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5098-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12282
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.515669
EE-01-FB85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.208601
GSE238005_5_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00351
periventricular stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.165
BRD-K72414522_AZD-5438_LNCAP_3_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PRPS1L1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00601696
AA-22-UI44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245473
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22279
GTEX-NFK9-2226-SM-3MJGP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18678
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6441-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFF	ENCODE Transcription Factor Targets	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOSL1	ENCODE Transcription Factor Targets	1.0	null
PROP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	91.0785
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Entinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00687246
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31889
GSE152699,GSE152723_0_v_1_vemurafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14107
NCIH2196	CCLE Cell Line Gene Expression Profiles	1.0	2.264
all	GWASdb SNP-Phenotype Associations	1.0	0.063537
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A45498368_WYE-125132_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Mesothelioma_MESO_TCGA-MQ-A6BS-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_15069_KD_Twist1_SRP150075	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.3546
PIAS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21512
VWA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00516976
Stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.815
GSE193027_1_v_0_krt19_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922674
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873274
GSE138019_1_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VNN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00673065
GSE146982_0_v_6_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ALOX5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00497027
Lung adenocarcinoma_LUAD_TCGA-44-8120-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26122955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2277
BRD-K58964288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2944
BRD-K65135171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05547
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPB-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7312-01B-21R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.WT.HP_24H:O13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.21537
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.965765
BE-27-RQ61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.408874
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.54504
SLR20	CCLE Cell Line Gene CNV Profiles	1.0	1.73329
valproic acid-989	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
Optic lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.053
GTEX-VUSG-0008-SM-4KL24	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18606
GSE158632_3_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE165682_0_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K42918627_GSK-2126458_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
18160665-TableS5	GeneSigDB Published Gene Signatures	1.0	null
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
median nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.287092
GSE146982_7_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
OTX2_silencing_GDS4472_136_human_D425 medulloblastoma (MB) cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Alcohol dependence	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.539794
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K88625236_-666_PHH_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
gentamicin-2082	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NPJ8-1426-SM-3MJHR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7293
TCFCP2L1-18555785-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-QCQG-0008-SM-48U2G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
GSE197686,GSE197688_2_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193351_4_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
STK39	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00567389
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41115
GSE168171,GSE168173_0_v_1_ddx41_human	RummaGEO Gene Perturbation Signatures	-1.0	null
flunixin-3411	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RAD21_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874794
disease of anatomical entity	GWASdb SNP-Disease Associations	1.0	0.09152
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.31088
BRD-K65257143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27935
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12462
H3K4me3_Adult Liver	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00452109
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.886391
GSE162892_3_v_5_isox_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EP300_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_AZD1480_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148485
molt4	HPA Cell Line Gene Expression Profiles	-1.0	-0.826749
TAL1_megakaryocyte_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE109140_2_v_3_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
dorsolateral prefrontal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.833525
GSE216043_11_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE217452_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.276
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2956-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.923326
GSE135030_11_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
CBLB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00570635
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
BRD-K06330738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19524
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.262986
Sarcoma_SARC_TCGA-DX-A6BA-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CF-42-OS28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210454
calcium ion-dependent exocytosis of neurotransmitter	GO Biological Process Annotations 2015	1.0	null
16288009-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Perturb_4491_KO_Tcf4_SRP072458	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Lung squamous cell carcinoma_LUSC_TCGA-37-4129-01A-01R-1100-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UC-00-QA88_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230771
collecting duct	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.319498
NR3C1-23031785-PC12-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
FF-06-MO73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.727481
Lung adenocarcinoma_LUAD_TCGA-05-4397-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.721694
Brain Lower Grade Glioma_LGG_TCGA-P5-A5F0-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.122672
BRD-K08416880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61331
NDC80	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00847545
GSE175787_13_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
TP53	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4264
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
SIRT1_KO_GDS4895_410_mouse_brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040784
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BE-92-TW08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220324
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_9498_KO_Lsd1_SRP096254	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
PMC12486367-Supplementary_Data2.pdf-8-ZNF441_ZNF441	Rummagene Transcription Factor Associations 2026	1.0	null
cerebral hemisphere	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.38326
MTTP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0062108
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2297
NR3C1	ChEA Transcription Factor Targets	1.0	null
BRD-K67578145_GDC-0879_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_Alvespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0107408
CA1 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.59223
tobramycin-2841	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_2917_KD_FOXO3_SRP325840	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.7886
EA-18-FP00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.359372
CRCGN017_MCF10A.WT.HP_24H:O09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.469
GSE128730_7_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KA-71-CQ35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.361897
nortriptyline-7422	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-34-8455-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.18396
DD-74-PJ26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.317483
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.89659
496100515_HIP_dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.66785
H3K27me3_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the retina	GWASdb SNP-Phenotype Associations	1.0	0.581386
pc-12 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.52556
BRD-K66214118	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50333
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.368891
CYP20A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00632419
Medullary reticular nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77568
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49865102_PD-0325901_A375_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
APP	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965041
GTEX-XK95-0008-SM-4AT5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
IV, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.996932
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39097
RUNX1-26923725-CHIP-SEQ-HPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958534
TSC22D4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K58194737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45645
DC-17-ZB19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.409743
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
A549_Hesperadin_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0251822
PMC6026875-MOL2-12-1104-s002.xlsx-List_of_Cancer_Associated_Molec-Tet-MIST1_Cancer_Molecules_BHLHA15	Rummagene Transcription Factor Associations 2026	1.0	null
MAPK8IP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25938
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE133763_0_v_2_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SUM1315MO2	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.601439
orbital frontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.897761
AD-51-BB90_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211774
GTEX-PLZ6-0008-SM-48TD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
esr1_21299862_mcf7_lof_human_gpl570_gds4065	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.009871
BRD-K53634892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34939
GTEX-QVJO-0008-SM-447AU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
BRD-K42918627_GSK-2126458_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE186112_1_v_0_med23_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31208
NUDT22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06235
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08386
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IO-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A60245366_AS-601245_SKBR3_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE172146_2_v_0_mettl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174701_1_v_6_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7617064-EMS151900-supplement-Figure_7_Source_Data.xlsx-HLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE143955_1_v_0_ripk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cerebellum	HPA Tissue Protein Expression Profiles	-1.0	-0.90266
A549_Ellagic acid_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0174925
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.854925
Perturb_10270_KO_Camk2d_SRP281889	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.27931
Pancreatic_Islets	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.03216
BRD-K81144230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12868
u138mg	HPA Cell Line Gene Expression Profiles	-1.0	-0.826749
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.72601
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	0.970347
BRD-K74881104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2784
MAFK_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.971222
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16114
LXR-22292898-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE162892_3_v_2_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12354803-42003_2025_8643_MOESM2_ESM.xlsx-2w_TP63_positive-Gene_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PW2O-0008-SM-48TEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37894
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7149918-12974_2020_1781_MOESM1_ESM.xlsx-Table_S7_CEBPB_Astrocyte_marker-Ensembl_ID_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
CC-68-YZ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.717992
A549_UNC1999_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0283002
NFATC2IP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17159
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.43899
KDM4E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00603986
GSE160083,GSE160084_1_v_0_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary visual cortex (striate cortex, area V1/17)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27094
cytoplasm	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CEBPB_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substantia nigra, reticular part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.21344
prochlorperazine-995	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC6344081-elife-40364-supp8.xlsx-PLZF-kd_2d_Diff_Vs_Ctrl_2d-diff-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
DCANP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00633435
AF-30-GH67_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257351
TEAD4-22529382-TROPHECTODERM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ABT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42967
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE71385_1_v_0_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:K08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.48865
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33005
ovary_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.933908
PMC3500769-srep00875-s3.xls-AP1-Time_4_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1143	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.30768
CRCGN017_MCF10A.WT.HP_24H:M11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1665
HCFC1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50702
GSE216273,GSE216292_0_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PDE6B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00475993
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75186244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23486
PMC4784386__F5	PFOCR Pathway Figure Associations 2024	1.0	null
A549_MC1568_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154277
rostral (anterior) extramural migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.22234
lycorine-6051	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.877142
renal corpuscle	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.18635
GSE176008_0_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.947031
GSE149901_2_v_1_anlotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.948334
AURKC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00627223
SARS-BatSRBD_36Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.35158
JAG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00556655
PMC9894241-pnas.2211429119.sd05.xlsx-G6_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-6217-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mimosine-2638	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SE5C-0008-SM-4B64J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02577
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of IC	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00441
regulation of exocytosis	GO Biological Process Annotations 2015	1.0	null
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.694432
vascular disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.042588
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTOR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00514284
OC-10-FB51_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290207
abnormality of the endocrine system	GWASdb SNP-Phenotype Associations	1.0	0.082374
BRD-K10058823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28298
GSE79572_0_v_1_pax8_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE134214_0_v_1_ell2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Postcentral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.037
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
artery disease	GWASdb SNP-Disease Associations	1.0	0.351355
GSE155852_0_v_1_apigenin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Benzbromarone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.62
periaqueductal gray substance, dorsolateral portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.904672
EWSR1_KD_GDS4962_466_human_Ewing sarcoma and prostate cancer	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LDLRAD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00718982
REG3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00524604
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1::TCF3	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33786
A549_S-Ruxolitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0154891
18318837-TableS1	GeneSigDB Published Gene Signatures	1.0	null
Infralimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40559
substantia nigra, compact part	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52432
FOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	100.713
sulfadimidine-3765	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K32118188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56711
BRD-K09106444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16989
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47769
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856444
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.95046
AU565	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.88899
HT-144	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.876151
BRD-K88179337	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16761
SARDH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65463
NCIH1573	CCLE Cell Line Gene Expression Profiles	1.0	1.95975
Oliva	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.834
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21769
BRD-K15427120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60594
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34125
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3465-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NFK9-0008-SM-4E3JE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30074
BRD-K40175214_torin-1_LNCAP_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
WNK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00535942
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.898953
SP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.07791
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0997
A549_Tubastatin A HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147205
496100465_HIP_possible Alzheimer's disease_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.31303
HS3ST3B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46522
BRD-K99525048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3198
Lung squamous cell carcinoma_LUSC_TCGA-39-5029-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LIVF001-011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14572
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062803
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.898953
BRD-K75100119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10129
BRD-K05939258	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68957
H3K27me3_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872837
hsa-miR-147	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
RAD21_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPIF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00601987
GSE244730_0_v_1_erlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.992005
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
etamsylate-4576	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A549_SRT3025 HCl_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.019534
GSE96649_1_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
primary auditory cortex (core)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05333
substantia nigra	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.585625
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Fastigial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42935
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
BRD-K42918627_GSK-2126458_HT29_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K13235291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18016
spironolactone-6255	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NFE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0080232
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225831
H3K4me1_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC8979909-13353_2022_690_MOESM1_ESM.xlsx-ESR1_targets-genes_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
vincamine-3865	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE250560_1_v_0_foxo1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MEF2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74571
GTEX-T6MN-0011-R8A-SM-32QP3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953956
Brain Lower Grade Glioma_LGG_TCGA-S9-A6UB-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VN-A88R-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25585
regulation of calcium ion-dependent exocytosis	GO Biological Process Annotations 2025	1.0	null
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.500831
BRD-K66351990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20043
parathyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.777364
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
BRD-K30111752	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36252
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63399
GSE159678_6_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NOP56	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01203
PMC9038526-mmc1.xlsx-postCOVID_ctr_vs_LPS-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
articaine-7272	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36677
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A7NN-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN013_HEPG2_24H:B13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.21097
GJD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00737412
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-PAX6_UNIQUE_DYS_GENES-PAX6_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE240027,GSE240030_5_v_0_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.WT.HP_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.65731
spironolactone-2064	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
disulfiram-6210	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-OU-A5PI-01A-12R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K5	GDSC Cell Line Gene Expression Profiles	-1.0	-2.36834
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.825749
gabapentin-3472	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21504
adrenal gland cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.191218
superficial stratum of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0783
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYK_druginhibition_285_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.50307
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22785
NCIH2405	CCLE Cell Line Gene CNV Profiles	1.0	2.10624
binding	GO Molecular Function Annotations 2015	1.0	null
NDUFAB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00411046
A549_Enzastaurin_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0171399
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218580_1_v_3_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
BRD-K63950697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27188
GC-69-JF03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220107
synapse part	GO Cellular Component Annotations 2015	1.0	null
CD-80-ZD47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.201916
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69716
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A4ZW-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SYK_knockdown_190_GSE54065	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.59031
REST-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
A549_NVP-BSK805 2HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147513
abnormality of blood and blood-forming tissues	GWASdb SNP-Phenotype Associations	1.0	0.053072
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
SMC3-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16582
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
alclometasone-6229	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE122067_3_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC7062471-elife-52504-supp6.xlsx-TEAD4_motif_in_OCR_around_DEGs-Gene_ID_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905961
C170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.49842
telencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.378372
THAP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.2864
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899473
BRD-K41895714_AS-605240_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE148510_1_v_2_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TYMS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00370295
amphotericin B-6303	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13098
ADGRA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01692
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.15008
GSE239688_2_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QEG4-0626-SM-2S1OY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2638
Orbital area, medial part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29561
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10829
CRCGN016_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30648
Brodmann area 36	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.429
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0008-SM-4DXT8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14674
GE-53-SM76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.656327
clomipramine-3182	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10699
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884959
intercalated nucleus of medulla	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37981
Dehydration_Hypothalamus_GSE3125	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.97548
GSE123825_0_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12999
DRD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0052496
CRCGN016_MCF10A.WT.HP_24H:P06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.20571
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77403
GSE142210_3_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
arteriosclerotic cardiovascular disease	GWASdb SNP-Disease Associations	1.0	0.490531
GTEX-S3XE-0008-SM-3NM8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47879
BC-61-BE07_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.414315
PMC11462941-CAS-115-2947-s001.pdf-239-THAP4_THAP4	Rummagene Transcription Factor Associations 2026	1.0	null
FDPS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4708
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.363082
GSE205730,GSE205731_2_v_3_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.25271
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-RNOR-0526-SM-2TF4O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0455
Galloway-Mowat syndrome 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.65
AB-85-JR73_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24394
SKMEL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.79262
16491124-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0728
SMCO4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00687586
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948373
small intestine	HPA Tissue Protein Expression Profiles	1.0	0.777364
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864287
GSE193258,GSE193259_2_v_4_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K40826084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91486
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.958912
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE162892_3_v_0_sox9_human	RummaGEO Gene Perturbation Signatures	1.0	null
BCL7C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0060773
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.25706
CA46	CCLE Cell Line Gene Expression Profiles	1.0	1.69309
CRCGN016_MCF10A.TP53.M_24H:E19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.84155
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.875742
OVTOKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
16474848-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5034-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-0526-SM-3NB2W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24459
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227731
superior rostral gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.830739
RAD21_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
CTCF-33576154-HUMAN-PERIGASTRICLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
vincamine-3976	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915598
H3K4me3_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
decreased pulmonary ventilation	MGI Mouse Phenotype Associations 2023	1.0	null
outer CP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03292
BRD-K29130550	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.8759
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09257
BRD-K35860167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73674
GSE195568_6_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K69852452_7241-4207_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CDX2-22108803-LS180-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K65086352	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14427
outer CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.842295
chr16_19210169_G_A_b38	GTEx eQTL 2025	1.0	1.22392
OVCAR5	BioGPS Cell Line Gene Expression Profiles	1.0	0.955737
diclofenac-445	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC-33	COSMIC Cell Line Gene Mutation Profiles	1.0	null
piracetam-2861	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CREB3L1_CREB3L1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.411
H3K27me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
diethylstilbestrol-4547	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03454
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5884
HINT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00729188
Tegmentum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.218
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04912
localization	GO Biological Process Annotations 2015	1.0	null
IL9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00581776
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05067
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19095
FOXP2	ENCODE Transcription Factor Targets	1.0	null
BRD-K48260102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02337
sotalol-4079	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormality of extrapyramidal motor function	GWASdb SNP-Phenotype Associations	1.0	0.684265
GSE244072_10_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.01183
BRD-K76908866_CP-724714_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE94849_1_v_0_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SB-01A-21R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Trichostatin A_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153913
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3IV-01A-22R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.47108
5279552-843	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43805
GTEX-QVUS-0226-SM-3GIJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29854
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-PKNOX1_PKNOX1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_CD14-positive monocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GPX4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00525087
GSE166004_1_v_0_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZM 336372	DeepCoverMOA Drug Mechanisms of Action	-1.0	-1.05
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S8-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2756-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826156
GSE145430_0_v_1_zmat3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IE-19-LI00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290326
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35128023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17555
GSE101112_6_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
valproic acid-1002	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y1-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94409042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.91717
PMC5629025-elife-27159-fig1-data1.xlsx-Direct_AR_target_genes-Control_only_genes_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K74039237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1798
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21883
CRCGN016_MCF10A.TP53.M_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.64824
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.928223
MYOD1	ENCODE Transcription Factor Targets	1.0	null
AE-85-KE62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.670839
lateral parabrachial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.869182
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05498
BRD-K96898856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17425
Skin Cutaneous Melanoma_SKCM_TCGA-RP-A693-06A-13R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
IRAK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00616622
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K40175214_torin-1_SKBR3_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	0.777364
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.948529
BRD-K90133770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11182
tardbp_19910924_hek293e_lof_human_gpl570_gds3730	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.308462
BRD-K86797399_pracinostat_HA1E_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dexpanthenol-1802	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SARS-CoV_24Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.52383
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8727
BRD-K99545815_PF-562271_HME1_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A549_Roxadustat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0246488
neoplasm of the lung	GWASdb SNP-Phenotype Associations	1.0	0.475918
NOZ	DepMap CRISPR Gene Dependency	1.0	2.25292
BRD-K62213484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.08463
Heart - Atrial Appendage	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.650393
PIK3C2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00734611
layer 3 of AOV cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00168
GSE86507,GSE86509_7_v_10_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
GSE145323,GSE145324_9_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T2YK-0008-SM-4DM6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07147
DMS454	CCLE Cell Line Gene Expression Profiles	1.0	1.37958
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF280C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27021
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
INF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00867666
EKVX	BioGPS Cell Line Gene Expression Profiles	1.0	2.04738
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54077
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.951335
central nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.241746
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the urinary system	GWASdb SNP-Phenotype Associations	1.0	0.104922
Cortical amygdalar area, posterior part, medial zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22214
ventral tegmental area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02231
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67138
serotonin-5633	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07619
CTCF_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.340103
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
disease of cellular proliferation	GWASdb SNP-Disease Associations	1.0	0.060427
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.7152
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12166
HUPT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51051
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872932
GSE154197_1_v_2_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
methoxsalen-5007	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PIGV	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00518945
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
intermediate stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.7047
Prestwick-682-4984	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A549_Ivosidenib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146957
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.70363
CRCGN012_HEPG2_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.18671
GTEX-UTHO-0008-SM-4JBID	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11588
CC-18-YW57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.358478
SIHA	DepMap CRISPR Gene Dependency	1.0	2.99812
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
L-168,049	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
syntaxin binding	GO Molecular Function Annotations 2023	1.0	null
secretion by cell	GO Biological Process Annotations 2015	1.0	null
cytoplasmic part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-WVLH-3126-SM-3MJGA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08575
A549_BRD4770_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0209599
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5117-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
temporal pole, right, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18861
corynanthine-2786	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Dorsal peduncular area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.76031
integral component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.13962
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_3H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19215
HSP90B1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00957164
GSE146982_4_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041108
GSE102467_1_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE121866_1_v_3_six4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3255	COSMIC Cell Line Gene Mutation Profiles	1.0	null
VGLL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0075049
C4orf3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21499
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10572
PPM1G	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00477607
Testis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.02764
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.73185
SLC12A5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00619705
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872143
GSE164529_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE146982_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.926476
NCI-H2106	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.68255
GSE96991,GSE97117_5_v_2_il11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JD-44-KF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300281
PCED1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11079
GTEX-U4B1-0008-SM-4DXUW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11392
GSE174701_1_v_2_maml3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40389
nrk-52e cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.812309
BRD-K49865102_PD-0325901_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Ventral posteromedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71261
oxyphenbutazone-4506	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K93755725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.93932
GSE228430_2_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229973_4_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
19204204-SupplementaryTable5	GeneSigDB Published Gene Signatures	1.0	null
BRD-K36168475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19474
GSE245270_1_v_3_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K49307935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43063
ZNF675	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	47.5818
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ventral posteromedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56135
BRD-K33868913	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08201
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.43157
TT2609C02	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55135
BC-54-ON71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.621875
organelle	GO Cellular Component Annotations 2015	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-7631-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Tanespimycin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0105265
skeletalmuscle_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.53141
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950116
ouabain-6680	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
5194442-6553	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AKT_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19183
IGSF9B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00754766
urinary system disease	GWASdb SNP-Disease Associations	1.0	0.182619
GSE202434,GSE202438_8_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67905
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
methazolamide-6268	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1M6-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DYRK1B	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22437
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.733016
H3K27me3_cardiac mesoderm_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS-53	GDSC Cell Line Gene Expression Profiles	1.0	1.47196
inner CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09589
NCIH2227	CCLE Cell Line Gene Expression Profiles	1.0	1.64711
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-7269-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K14681218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09261
glibenclamide-3163	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
asiaticoside-7244	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletalmuscle_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.39979
positive regulation of cell growth	GO Biological Process Annotations 2025	1.0	null
Secretory vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
UBE2D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.72376
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STOCK1N-35874-6583	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
oxedrine-7150	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K65945126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17011
GSE214382,GSE214383_1_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28927
NUGC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.44979
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	1.0	null
heart conduction disease	GWASdb SNP-Disease Associations	1.0	0.714351
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.836466
GSE193351_1_v_0_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
12096084-Figure3-1	GeneSigDB Published Gene Signatures	1.0	null
PPP1CC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02954
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF558	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	178.617
abnormality of the posterior segment of the eye	GWASdb SNP-Phenotype Associations	1.0	0.194188
BRD-K04623885_BIBR1532_VCAP_24.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIRT1_Deficiency_GDS4895_316_mouse_Brain	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925339
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A634-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormality of the face	GWASdb SNP-Phenotype Associations	1.0	0.136844
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2243
BRD-K05804044_AZ-628_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18611
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	2.05765
BRD-K09434518	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62403
IP6K2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00501937
GCKR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00483828
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213797
Tanycyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.689
20145155-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE148066,GSE157787_5_v_6_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-IF-A4AJ-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.35209
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23318
CRCGN015_MCF10A_48H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.38697
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Suprachiasmatic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.2
Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AGTR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00484177
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43051
Liver hepatocellular carcinoma_LIHC_TCGA-NI-A8LF-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JNK_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
IC-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.53
GTEX-WL46-0126-SM-3TW8I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864391
FB-49-NW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.295477
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239541_8_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SW48	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7067-01A-11R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of regulated secretory pathway	GO Biological Process Annotations 2025	1.0	null
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985321
BRD-K52911425_GDC-0941_A549_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-IR-A3LA-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMT2E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00457377
GSE196104,GSE196106_2_v_1_vsx2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:L02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18372
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89605
GSE210951_1_v_0_islr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dehydration_CNS - Brain - Hypothalamus (MMHCC)_GSE4130	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.57775
denatonium benzoate-5480	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE117212,GSE117214_2_v_1_zbtb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VB-89-RG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216128
GSE214382,GSE214383_6_v_2_ascl1_human	RummaGEO Gene Perturbation Signatures	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211793
BRD-K38487270	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08802
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIGD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00594959
19914252-Table1	GeneSigDB Published Gene Signatures	1.0	null
Spinal Muscular Atrophy, Infantile_CNS - Spinal Cord (MMHCC)_GSE3075	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.14199
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.879498
semustine-7545	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.4219
noscapine-5851	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.83791
GTEX-S95S-0008-SM-4AT5M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01247
SULT1C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16609
promethazine-6477	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K77908580_entinostat_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.977384
GSE225900_1_v_0_hsdl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE216043_11_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
chlortetracycline-1541	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48929
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43323
GTEX-OOBJ-0008-SM-3NB26	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28955
CTCF_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08767
BRD-K15975627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21209
CCNT2	ENCODE Transcription Factor Targets	1.0	null
GSE193258,GSE193259_2_v_3_osimertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.898025
BRD-K05804044_AZ-628_A375_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TRIO	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00517761
superficial stratum of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17026
BRD-U61997977_WZ-4-145_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ELF4_ELF4	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_POU5F1_20526341	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular component organization or biogenesis	GO Biological Process Annotations 2015	1.0	null
postsynapse	SynGO Synaptic Gene Annotations	1.0	null
SKOV3	BioGPS Cell Line Gene Expression Profiles	1.0	1.75594
outer CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.37407
nialamide-4525	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cerebellar cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13391
quinisocaine-2807	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, lateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20058
DYNLRB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03039
Subiculum, ventral part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40381
GSE129241_3_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
OE-31-YC41_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.767002
Brain Lower Grade Glioma_LGG_TCGA-DU-6400-01A-12R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4TZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE175787_11_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
BA-06-RE84_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.550557
hypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.176233
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.91981
Posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19846
H3K27me3_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7673140-41467_2020_19575_MOESM4_ESM.xlsx-Data_S1d-List_of_2302_of_genes_differentially_regulated_by_SOX2_FDR_0_1_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K36740062_GSK-1070916_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Piriform area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.882
Neurosphere_Cultured_Cells_Cortex_Derived	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.82679
Acute Myeloid Leukemia_LAML_TCGA-AB-2985-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
single-organism process	GO Biological Process Annotations 2015	1.0	null
GTEX-U4B1-1426-SM-4DXTX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21331
A549_AZ 960_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156586
PMC9894241-pnas.2211429119.sd05.xlsx-G2_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN017_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.31015
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NR-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Nephritis	CTD Gene-Disease Associations	1.0	1.09506
BRD-A29901043_KIN001-127_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13877
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	1.0	0.938041
Pemigatinib_BT-474	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0227966
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10563
BRD-K01225247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10908
APLP2_KO_GDS4414_536_mouse_adult cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.530692
A549_TMP195_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145213
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31889
urinary tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.111247
Perturb_4353_KO_Pten_SRP260985	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.94025
BRD-A19500257_geldanamycin_MCF10A_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9843885-40478_2023_1507_MOESM6_ESM.xlsx-CIC-OE_TS603-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4LF-0426-SM-3NMB5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825057
RELL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00685658
GTEX-XYKS-2426-SM-4AT43	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938712
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TOLLIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08484
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32907
BRD-K37312348_Kenpaullone_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-A89554862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60026
GTEX-Q734-0008-SM-48U2I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02232
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20136
BRD-K70401845_erlotinib_HCC515_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K29415052_NVP-BGT226_A549_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE111247_11_v_4_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COLO-679	GDSC Cell Line Gene Expression Profiles	-1.0	-1.86188
BRD-K56065989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16988
granule cell layer of the DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.69587
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64052750_gefitinib_HCC515_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LRP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11289
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0613
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06158
Parkinson's disease or first degree relation to individual with Parkinson's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.05229
carcinine-4225	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
AD-09-TD34_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223153
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
moxisylyte-1682	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
CRCGN014_HEPG2_24H:D01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02233
BRD-K53903639_480743.cdx_VCAP_24.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
19204204-SupplementaryTable1	GeneSigDB Published Gene Signatures	1.0	null
GSE188869,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K44227013_ponatinib_HCC515_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SETDB1-19884255-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC11046918-12967_2024_5211_MOESM5_ESM.xlsx-C_FUS-DDIT3-eGFP_vs_eGFP-Table_S3_Regulated_genes_between_scaffold-cultured_HT1080_FUS_DDIT3-eGFP_cells_and_control_cell_lines_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
LF-94-HB11_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.28007
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Medullary reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22046
L-540	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE245270_1_v_0_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
EGR1	ENCODE Transcription Factor Targets	1.0	null
(+)-chelidonine-5760	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SMC1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0139585
GSE135030_8_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8423434-mmc7.xlsx-KLF4_HENSM-Genes_n_2172_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
UNC119	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00514403
organelle fusion	GO Biological Process Annotations 2015	1.0	null
BRD-K81418486_vorinostat_HCC15_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_Valproic acid sodium salt_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147165
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SARS-BatSRBD_24Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.68292
A549_AICAR_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0315814
CAY-10397-7071	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ABT-199	DeepCoverMOA Drug Mechanisms of Action	1.0	0.28
ZBTB16	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00832971
integral component of membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.194698
GSE128730_3_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCT116	BioGPS Cell Line Gene Expression Profiles	1.0	1.20792
DCTN6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72191
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30691
BRD-K06958718	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55765
GSE175787_8_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDT8-0011-R4A-SM-32PKM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.994133
NCIH69	CCLE Cell Line Gene Expression Profiles	1.0	1.83669
SUZ12	ChEA Transcription Factor Targets	1.0	null
CP-320650-01-3825	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K11168234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16626
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
coated vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12036
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NA-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tranexamic acid-2085	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE165682_0_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GA-88-CF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.534552
SK-MM-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.84409
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP2R5C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00478432
BRD-K06956443	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53271
MCMBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00553325
GSE144231_4_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12518476-10067_2025_7574_MOESM9_ESM.xlsx-Sheet2-RNAseq_DEGs_of_KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
mRNA_SUZ12_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
BRD-K74148702_curcumin_SKLU1_6.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DAUDI	COSMIC Cell Line Gene Mutation Profiles	1.0	null
C33A	DepMap CRISPR Gene Dependency	1.0	3.79334
internal segment of globus pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.18489
CRCGN015_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09457
HCC1395	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K07013504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92882
A549_GSK J1_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0199346
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K02708799_GSK-1059615_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.2587
GTEX-RN64-1826-SM-48FDV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01904
GTEX-T5JW-0008-SM-4DM5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7X3-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PADI2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00526402
BRD-K85909950	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11884
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K77638937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01874
PPM1G	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29894
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF12A	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.595417
GSE126345_2_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PPIP5K1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00647878
Cortical amygdalar area, posterior part, medial zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22785
IRS4_KO_GDS1219_306_mouse_brown preadipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-RM2N-0008-SM-48FF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36738
BRD-K40175214_torin-1_SKBR3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A39996500_radicicol_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PMC7806814-41598_2020_80145_MOESM3_ESM.xlsx-CombinedResults_TreatbySexMainE-Supplementary_Table_S2_Genes_with_significant_FDR_0_05_sex_by_LPS_treatment_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K09598619	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.023
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53565
Prostate adenocarcinoma_PRAD_TCGA-EJ-7782-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
PMC12146336-Data_Sheet_1.pdf-12-ENSG00000196092_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K14210122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13763
GSE178714_1_v_4_smad2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0105
BRD-K32191695	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16025
A549_Rucaparib_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164489
renal artery	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.395331
Perturb_18111_KO_Eed_SRP132909	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.86193
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AG-06A-31R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crohn's disease_Intestine - Large Intestine - Colon (MMHCC)_GSE6731	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.93786
GTEX-QVUS-0011-R1A-SM-3GAD2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2342
MD-86-UW46_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235152
Ebolavirus(ZEBOV)_6day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.279767
PAX5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149359_2_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K93197397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45194
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30015
Entorhinal area, lateral part, layer 2b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06667
A549_Ki8751_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0150278
GSE134375_3_v_7_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
LY-294002-6976	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE138019_1_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AC-30-XU83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.483448
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
neuroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063318
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10699
GSE182727_1_v_0_busulfan_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE111247_14_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ChIP_REST_18959480	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70873
FOXH1-21741376-EPCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE258991_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ramipril-6792	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
perinuclear region of cytoplasm	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.524704
MF-37-KQ09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211395
APTX	Pathway Commons Protein-Protein Interactions	1.0	null
GSE237984_1_v_0_magi1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ME-31-RM40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.5647
Sarcoma_SARC_TCGA-PC-A5DN-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70717477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33334
BRD-K86574132_-666_VCAP_24.0_h_48.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46639367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.09197
Parkinson's disease	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.8
Taenia tecta, dorsal part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05982
PMC8635809-Table_2.xls-LPS-upregulated-Unnamed_4_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
A549_SRT2104_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0135362
NANOG-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE146982_4_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE238018_3_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XGQ4-1626-SM-4AT6J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01588
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K63711467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05577
GTEX-N7MS-0008-SM-4E3JI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21235
Dentate gyrus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.361
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.001509
GSE240468_3_v_2_nfyc_human	RummaGEO Gene Perturbation Signatures	1.0	null
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.55578
STAT1	ENCODE Transcription Factor Targets	1.0	null
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2832-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K55606442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16509
PMC7594423-12915_2020_895_MOESM13_ESM.xlsx-Table_S6D-Table_S6D_-_Differentially_Expressed_genes_shared_between_BRCA_TRIM25_amp_and_STAD_CIC_Del_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_8387_OE_EFTUD2_SRP271829	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.31866
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67186
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57493
calcium-dependent phospholipid binding	GO Molecular Function Annotations 2025	1.0	null
lung	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
CTCF_SK-N-SH_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146982_0_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
vascular disease	GWASdb SNP-Disease Associations	1.0	0.281518
CRCGN015_MCF10A.WT.HP_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.86703
BRD-K72381041_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE144231_2_v_1_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Calyx of Held	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.934
pyridoxine-2751	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-1.39546
HTMMT	DepMap CRISPR Gene Dependency	1.0	3.40524
LC-2-AD	COSMIC Cell Line Gene Mutation Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.910607
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T6-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE172016_2_v_0_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
FA-63-WI26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.532315
GSE229973_3_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BD-69-XG81_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202227
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.898332
CRCGN016_MCF10A.WT.HP_24H:L23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0965
GTEX-X4EP-0011-R2B-SM-3P625	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832332
PMC11033585-BLOOD_BLD-2023-021752-mmc2.xlsx-S11_DGEA_CDKN2A_PAX5-Supplemental_Table_11_Differentially_expressed_genes_between_CDKN2A_PAX5_and_all_other_subcluster_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
REST	ChEA Transcription Factor Targets	1.0	null
BRD-K67868012_PI-103_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6211-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE229580_2_v_3_creb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
VIIIA, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14776
NCIH1836	CCLE Cell Line Gene Expression Profiles	1.0	1.49769
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13065
bucladesine-3483	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Retinal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.712
VIIAf	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09311
idazoxan-5347	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
KC-48-OO62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.85542
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD3E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00640966
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.919503
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871714
BRD-K57282030_JW-7-24-1_A549_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T5JW-1826-SM-3GAE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00696
GSE192663_3_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LMO2-26923725-CHIP-SEQ-HEMOGENIC-ENDOTHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SP in primary somatosensory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.826265
BRD-A67508925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8817
cardiovascular system disease	GWASdb SNP-Disease Associations	1.0	0.678541
BRD-K77908580_entinostat_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K68041793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11748
NUGC3	CCLE Cell Line Gene CNV Profiles	1.0	1.4588
GTEX-PWN1-0008-SM-48TEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05939
superficial stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51381
outer CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.77548
KLF5-25053715-YYC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25698
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.11531
CH-223191	DeepCoverMOA Drug Mechanisms of Action	1.0	1.31
IDH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00563255
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.935941
cdx2_20696899_caco2_lof_human_gpl570_gse22572	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.132314
lipid metabolism disorder	GWASdb SNP-Disease Associations	1.0	1.33606
GTL-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.899782
rostral division of OFCi (area 11)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.14003
prostate_4a	HPA Tissue Sample Gene Expression Profiles	1.0	1.02302
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
carteolol-4096	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE233679_5_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFJO-0008-SM-4LVN7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
nervous system disease	GWASdb SNP-Disease Associations	1.0	0.095918
A549_Veliparib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.015836
HA-17-MS45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214147
HEY1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7816
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.916552
raphe nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.6534
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K42918627_GSK-2126458_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SPATA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00735432
BRD-K60907484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10563
GSE116810_5_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WH7G-1726-SM-4LVKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06823
BRD-K72437469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3597
GSE146982_7_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
physical disorder	GWASdb SNP-Disease Associations	1.0	0.418628
connecting tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.89817
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12077693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18947
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88034
GSE81803,GSE81912_3_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateropallial amygdalopiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05754
dorsolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.849075
periventricular stratum of Str	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36295
RL7	BioGPS Cell Line Gene Expression Profiles	1.0	0.833799
OS-RC-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51336
BRD-K79090631_CGP-60474_PC3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PKP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71258
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11647
olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.825686
BRD-K49328571_dasatinib_HT29_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.991868
BRD-K40175214_torin-1_A549_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R3RS-0008-SM-48FF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.992623
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23328
thoracic cancer	GWASdb SNP-Disease Associations	1.0	0.462164
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130437_2_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Bed nucleus of stria terminalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.973
GSE133213_6_v_13_znrf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
mefexamide-2121	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-R55E-0011-R8A-SM-2TC66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0421
BA-69-TQ80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.390803
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.339702
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51575138_TPCA-1_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.0429
eucatropine-4316	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4713-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
central nucleus of the inferior colliculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00568
coralyne-2652	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MEF2D_KD_GDS4759_339_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.6347
IRS2_KO_GDS1219_304_mouse_brown preadipocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.910726
BRD-K14241686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0949
GSE150669_0_v_1_roxadustat_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cefalexin-4654	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE202434,GSE202438_15_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48397
Lung squamous cell carcinoma_LUSC_TCGA-85-7696-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A45498368_WYE-125132_MCF10A_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Ospemifene	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.42
A549_Tanespimycin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0133977
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00028
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NBEAL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.05971
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988127
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular response to oxygen-containing compound	GO Biological Process Annotations 2023	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TKQ2-0008-SM-4DM5L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02822
BRD-K73952959	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51631
GSE126345_9_v_3_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dexpanthenol-7455	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE185139_1_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A.TP53.M_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.45865
RAD21	ENCODE Transcription Factor Targets	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
synaptic vesicle transport	GO Biological Process Annotations 2015	1.0	null
AG-012559-6920	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hMPV_12Hour_18234263_GSE8961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.74721
BRD-K63068307_ZSTK-474_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.495857
CORL24	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4516
Lung squamous cell carcinoma_LUSC_TCGA-58-A46L-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PLOD3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00253412
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01134
BRD-A45498368_WYE-125132_SKBR3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K80431395_TRICIRIBINE_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DNAAF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00562774
Dystrobrevin complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.967
BRD-K98404142_16beta-Bromoandrosterone_VCAP_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1586
GSE205070_2_v_7_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K36575476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46519
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.951335
EIF4G1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15846
GTEX-PWO3-0011-R6A-SM-2I5F3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10917
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U3ZH-0926-SM-4DXU4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.842537
A549_Mesna_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0135695
BRD-K53647853	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79106
sulfametoxydiazine-6212	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10Z-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EDA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0064431
frontal lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.412391
GSE130401_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
r2 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25792
BRD-K44856541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53722
CRCGN017_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.35705
Ventral posterior complex of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50996
r10 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.73907
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903397
WA-03-IF37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230916
8505C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A459-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.230547
GCIY	CCLE Cell Line Gene CNV Profiles	1.0	1.36576
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229973_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21638
GSE157594_3_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:L19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.4183
p2 portion of the substantia nigra pars compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00065
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE131161_2_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
trichostatin A-3566	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205730,GSE205731_2_v_0_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
atropine oxide-4476	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_MCF10A_48H:F01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	5.3869
GC-04-UF36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.607332
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
GTEX-XUW1-0826-SM-4BOP6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33254
GTEX-X4XX-0011-R1B-SM-3P622	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966831
PMC3500769-srep00875-s3.xls-PAX2-Time_4_PAX2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12763
EC-62-OE64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.8186
hnf1b_16297991_hek293_embryonic_gof_mouse_gpl96_gds1499	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.779298
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.098109
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.949177
Accessory olfactory bulb, mitral layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32512
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-TSE9-0011-R4A-SM-3DB7H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4326
brain stem	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.264696
PD 123319	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.31
AB-21-VE32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.265229
YA-78-MS95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.22742
Dendritic tuft	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.576
PAX5_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8069_KD_SFPQ_SRP281189	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.24054
Adipose - Subcutaneous	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.678809
GSE154074_2_v_4_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K67027685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38398
A549_Belinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0125536
GTEX-QEL4-0626-SM-3GIJM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1282
PMC7617064-EMS151900-supplement-Extended_Data_Figure_5_Source_Data.xlsx-CLC_D9_DEG-Logfold_change_threshold_1_0_1_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
DNMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85424
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A5ZF-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PA1	DepMap CRISPR Gene Dependency	1.0	5.07915
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE207135_2_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	1.0	null
S0-EE-WJKI_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223806
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51594
GTEX-R55E-0526-SM-2TC6B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888844
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193541_1_v_3_nifurtimox_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7HH-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ovary_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.897479
BRD-K38854468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42436
P3H3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00501882
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SW-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LS-1034	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44041
SHP77	CCLE Cell Line Gene CNV Profiles	-1.0	-1.82932
NFIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.7061
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03352
Ebolavirus(ZEBOV)_7day_PBMCs_rNAPc2treated_21987740_GSE24943	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.44057
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCEA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10698
HEB	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE147876,GSE147877_4_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
XRCC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3994
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.79058
substantia nigra, pars compacta, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.71929
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_BMS-911543_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0176027
ZBTB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9241
EBF1	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_cardiac mesoderm_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Synaptotagmin-17	InterPro Predicted Protein Domain Annotations	1.0	null
EE-98-PF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.460682
E2F6	ENCODE Transcription Factor Targets	1.0	null
BRD-K42918627_GSK-2126458_LNCAP_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
m2 part of nucleus parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37849
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE217873_1_v_0_nusap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.39521
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
Exocytic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Inferior colliculus, central nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13771
GSE184902_3_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Entorhinal area, medial part, ventral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08658
inner CP in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.85144
esculin-3390	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ESR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADCYAP1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03979
AICDA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00818435
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7149918-12974_2020_1781_MOESM1_ESM.xlsx-Table_S7_CEBPB_Astrocyte_marker-Symbol_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S32W-1926-SM-4AD63	GTEx Tissue Sample Gene Expression Profiles	1.0	0.915443
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00530465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61879
CRCGN015_MCF10A.WT.HP_24H:P19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.60409
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61496
GSE67266_7_v_3_etoposide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043118
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-27-BW40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.273624
abnormality of lipid metabolism	GWASdb SNP-Phenotype Associations	1.0	0.368659
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959003
GSE248769_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K63654001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2857
GTEX-NL3G-0008-SM-4E3JX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57841
karakoline-4297	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36343
BRD-A98888138	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54376
KARPAS299	CCLE Cell Line Gene CNV Profiles	1.0	2.09259
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868552
H3K4me3_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K40862705	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32908
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.906062
abnormality of metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.146035
cerebellar cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.891399
NUSAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00348932
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AC-30-XU83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.378152
CACNG8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42383
abnormality of cells of the erythroid lineage	GWASdb SNP-Phenotype Associations	1.0	0.258057
abnormality of the level of lipoprotein cholesterol	GWASdb SNP-Phenotype Associations	1.0	1.02638
A549_Fluorouracil_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0196145
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YW-0008-SM-4E3IE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02358
urinary system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.113014
Perturb_15071_OE_Fezf2_SRP041818	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.77208
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3776
BRD-K12994359_Valdecoxib_VCAP_24.0_h_177.6_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.917176
PKM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00832981
oxolamine-4969	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Mocetinostat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00634474
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN008_HEPG2_24H:J12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.479
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE149000_2_v_0_cyp3a5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE150134_1_v_0_fluorouracil_human	RummaGEO Drug Perturbation Signatures	1.0	null
perhexiline-5081	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE242647_2_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
H3K4me1_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE94814_1_v_0_reck_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cisplatin_mus musculus_gpl339_gds3099	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RMUGS	CCLE Cell Line Gene Expression Profiles	1.0	1.96477
EP300	ENCODE Transcription Factor Targets	1.0	null
eye disease	GWASdb SNP-Disease Associations	1.0	0.116148
BRD-K74261250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53175
Entorhinal area, medial part, ventral zone, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10724
salsolinol-4232	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WK11-0526-SM-3NB3O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875866
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.565591
MAZ	ENCODE Transcription Factor Targets	1.0	null
dinoprost-3308	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cellular response to metal ion	GO Biological Process Annotations 2023	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4994-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BE-79-QU25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213171
A549_Danusertib_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133004
butirosin-6080	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K74211805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00084
vancomycin-2858	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QESD-0008-SM-447B2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998599
BRD-K37865504_-666_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
pons	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.511384
parasubthalamic nucleus (migrated)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91946
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K92974694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02691
Posterior amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12728
BRD-K03353688	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19177
15735024-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Inferior olivary complex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.874
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.373672
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.12821
epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055445
GTEX-S4UY-0008-SM-3NM8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51893
GTEX-OHPM-0008-SM-4E3IP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16068
BRD-K83815065	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01464
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.63864
Thymol_BT-474	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0160043
BRD-K48861177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36131
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04761
FC-13-VS25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.247268
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
A549_Flavopiridol HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165226
CAL120	CCLE Cell Line Gene CNV Profiles	-1.0	-2.14726
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Glutamatergic synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
ABCB9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00699253
pka	GeneRIF Biological Term Annotations	1.0	null
DMS153	CCLE Cell Line Gene Expression Profiles	1.0	1.47756
sirolimus-1001	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K66189308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18914
Perturb_12683_KD_circEZH2_SRP388087	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.2269
regulation of localization	GO Biological Process Annotations 2015	1.0	null
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE94849_1_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
CW-051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02118
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.26866
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.656413
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33323
r9 part of the lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07361
BRD-A37523642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38199
STS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00436938
ribavirin-7316	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51126
ETS1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Substance dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
RXF393	GDSC Cell Line Gene Expression Profiles	-1.0	-2.67367
salicyl-alcohol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42115
USF	MotifMap Predicted Transcription Factor Targets	1.0	null
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1650	CCLE Cell Line Gene CNV Profiles	1.0	2.1597
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100576_HIP_dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.36496
piperine-4247	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
regulation of regulated secretory pathway	GO Biological Process Annotations 2023	1.0	null
A549_AC480_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178355
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vesicle-mediated transport	GO Biological Process Annotations 2015	1.0	null
diabetes mellitus	GWASdb SNP-Disease Associations	1.0	0.678541
BRD-K92902323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02113
GTEX-R55D-0626-SM-3GAD5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22908
CRCGN017_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.34
OTULINL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20355
H3K27me3_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DUOX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00536234
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K70426100	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21907
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.64635
Prostate adenocarcinoma_PRAD_TCGA-HC-7211-11A-01R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
19658189-TableS4	GeneSigDB Published Gene Signatures	1.0	null
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828795
BRD-K42918627_GSK-2126458_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
QDPR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00525892
GSE143944_1_v_0_ribociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CAL148	CCLE Cell Line Gene Expression Profiles	1.0	1.4886
ets_00000000_2008_ovarian_cancer_cells_gof_human_gpl6244_gse21129	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.208639
AC-28-RT00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.331833
GADD45B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00369806
GSE130690,GSE130692_2_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRK-0008-SM-3NB28	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07187
BRD-K45642123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26327
BRD-K21732483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87671
GSE146982_0_v_6_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
6-azathymine-3987	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE165682_4_v_5_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40356
NR6A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65063
H3K27me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06675
EE-98-PF86_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.361239
caudal division of IPC (area 39)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.69661
CDK18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25328
neoplasm by anatomical site	GWASdb SNP-Phenotype Associations	1.0	0.078267
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8041-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
p1 part of parabrachial pigmented nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2134
BRD-K95664364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09896
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.46321
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-T2IS-0011-R2A-SM-32QPF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09044
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.868289
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
IDH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18614
GSE211128_4_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
mRNA_KLF4_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-1.34331
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.82434
nifenazone-2122	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Parkinson's disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.015
NCI-H2196	GDSC Cell Line Gene Expression Profiles	1.0	1.67761
betamethasone-valerate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32354
BRD-K93663012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09669
valproic acid-1665	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01553
TREML1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00586326
GSE126345_2_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
diabetes mellitus	GWASdb SNP-Phenotype Associations	1.0	0.581386
GSE135514_2_v_5_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Alcohol dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
UACC893	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.704902
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.03124
BRD-K68174511_torin-2_SKBR3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EMP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0046194
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.556074
BRD-U51024685_HG-6-64-01_HCC515_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Sox6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7992
BRD-K87516578	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42944
BRD-K90697693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	7.6103
triflusal-7451	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K59369769_tozasertib_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lateral geniculate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.643
TP63	JASPAR Predicted Transcription Factor Targets	1.0	null
LILRB4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00599963
Lung squamous cell carcinoma_LUSC_TCGA-O2-A52Q-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
19101988-Table2a	GeneSigDB Published Gene Signatures	1.0	null
Dorsal nerve cord	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.506
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40389
CRCGN015_HEPG2_48H:C15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.04849
golgi apparatus part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.002666
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CA3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605525
BRD-K96250732	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.45742
intermediate stratum of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.89213
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K40175214_torin-1_A549_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KYSE30	DepMap CRISPR Gene Dependency	1.0	2.63325
Prostate	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
Perturb_15147_KD_EHF_SRP081174	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.67887
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.956127
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229973_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsal part of PcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75746
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1385	CCLE Cell Line Gene Expression Profiles	1.0	2.00559
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5921
A549_UNC1999_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.012958
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100582_HIP_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.44314
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE125219,GSE125221_4_v_8_arid1a_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
Testis	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.665471
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CL14	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4636
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3433-01A-02R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3453
cellular_component	GO Cellular Component Annotations 2015	1.0	null
abnormality of the kidney	GWASdb SNP-Phenotype Associations	1.0	0.581386
Cortical amygdalar area, posterior part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03839
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.997982
H3K27me3_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abnormal respiratory system morphology	GWASdb SNP-Phenotype Associations	1.0	0.126083
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874066
tegmentum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.404039
A549_G007-LK_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0270958
18537973-SuppTable1b	GeneSigDB Published Gene Signatures	1.0	null
BRD-K51544265_cabozantinib_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34576
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cerebral peduncle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.857
Perturb_13614_KD_Srrm4_SRP041656	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
anterior (rostral) cingulate (medial prefrontal) cortex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13256
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZA-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JE-72-KV75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.689996
QE-18-WG07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254518
OSTC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23693
BRD-K78659596_MLN2238_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
salsolidin-4226	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prestwick-664-6033	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PAX5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BTBD19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00819576
BRD-K38574421	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54557
Dendritic microtubule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.859
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02902
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K97784715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64485
BRD-K83115435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17053
valproic acid-1214	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RBFOX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0049993
GTEX-SSA3-0008-SM-47JWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
chlorambucil-4523	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DLG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00449928
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00475
GTEX-X4EP-3226-SM-3P5YR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11362
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.8996
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3922
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.4856
Lung adenocarcinoma_LUAD_TCGA-75-7025-01A-12R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31524
CHP-134	COSMIC Cell Line Gene Mutation Profiles	1.0	null
STOCK1N-35215-6422	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
GTEX-XPT6-0008-SM-4B64Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2824
GSE206729_4_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231891_1_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_8602_KO_Mir132_SRP064164	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.3974
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.5058
GTEX-UPK5-1426-SM-4JBHH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993513
alpha-estradiol-1210	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13725
ZR75_1	BioGPS Cell Line Gene Expression Profiles	1.0	1.06031
medrysone-3603	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K03406345_azacitidine_HEPG2_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SOX9	ChEA Transcription Factor Targets	1.0	null
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42386
fulvestrant-4429	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871525
FOXA1-21915096-LNCAP-1F5-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279275
GTEX-R55C-1726-SM-3GADJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07151
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JX-A3PZ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
15897907-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A81D-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062398
SRMS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00561352
RAD21_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281302
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE147876,GSE147877_2_v_11_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
LY-294002-1661	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
lomustine-7089	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K14707716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.092
mantle zone of AOD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17026
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12146336-Data_Sheet_1.pdf-12-PAX5_PAX5	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K61287439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05734
H3K27me3_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69480055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2262
clidinium	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20194
STAT3	MotifMap Predicted Transcription Factor Targets	1.0	null
ALAS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00230886
GSE240030,GSE252532_0_v_2_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
trans-golgi network	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.411039
A549_Azacitidine_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0128379
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53629
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KCI-MOH1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950116
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193258,GSE193259_9_v_13_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
synucleinopathy	GWASdb SNP-Disease Associations	1.0	0.787271
GSE216540_0_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166315_2_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE176008_7_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
apramycin-7334	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BE-79-QU25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.298404
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.03884
GSE153871_5_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE131161_5_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.91995
GTEX-T6MO-0008-SM-4DM6T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
SW756	DepMap CRISPR Gene Dependency	1.0	2.10095
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIRT1_KO_GSE28790_47_mouse_brain (3 mo)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
MRPL57	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36716
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.885448
Transport vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
GTEX-S3XE-0426-SM-3K2AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04658
BRD-K43620258_3,5-dichloro-2-hydroxy-N-(2-methoxy-5-phenylphenyl)benzenesulfonamide_A673_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE200839,GSE233826_3_v_6_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.127
Subfornical organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.787
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41311
GSE156923_2_v_1_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12869_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	80.5906
GSE193258,GSE193259_9_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
OAZ2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0068167
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15957
GSE205070_1_v_6_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE172016_2_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
PDE10A_KO_GDS4542_291_mouse_striatum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Cholesterol	dbGAP Gene-Trait Associations	1.0	0.672599
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.69716
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.89201
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00335721
NFRKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44868
GSE125014_1_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K99252563_QL-XII-47_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MC-40-IP75_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.325231
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16730910_regorafenib_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE216043_11_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BC-54-ON71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.379989
A549_Baricitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0215833
Small intestine carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.043
Ciliary epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.753
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
mRNA_OTX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CRCGN017_MCF10A.WT.HP_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2144
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24443
nitrendipine-5405	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cation binding	GO Molecular Function Annotations 2015	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.7064
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7407-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r8 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23071
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02166
BRD-K79254416_decitabine_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Dense core granule	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.23
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.85836
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976127
Congenital Abnormalities	CTD Gene-Disease Associations	1.0	1.01966
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast - Mammary Tissue	GTEx Tissue Gene Expression Profiles 2023	1.0	2.67314
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K69918256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31923
tiletamine-7311	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
trans-golgi network	GO Cellular Component Annotations 2015	1.0	null
GTEX-XMD3-0008-SM-4AT4V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895069
outer CP in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.68113
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31889
MATH1	MotifMap Predicted Transcription Factor Targets	1.0	null
NCIH510	CCLE Cell Line Gene CNV Profiles	1.0	3.2803
H3K4me3_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CHP-134	GDSC Cell Line Gene Expression Profiles	1.0	1.81674
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962766
BRD-K21025364_NVP-TAE226_HT29_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
lidocaine-4596	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-2926-SM-3MJGQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30327
GTEX-SJXC-2026-SM-4DM6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904804
BRSK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00559217
BRD-K07160586	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31584
Bladder Urothelial Carcinoma_BLCA_TCGA-E5-A4U1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUM44PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.922045
PMC9948080-Table_1.xls-Sheet1-BACH2_BACH2	Rummagene Transcription Factor Associations 2026	1.0	null
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02534
MITF	ChEA Transcription Factor Targets	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZFP14	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.1648
MAX	ENCODE Transcription Factor Targets	1.0	null
CAL-120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.976276
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
WC-16-IR43_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279823
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0078
FOXA1	ENCODE Transcription Factor Targets	1.0	null
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RD-90-DS77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.390929
A549_AZ 960_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0189843
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29406
BRD-K86050213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32069
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
synaptic vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
regulation of dopamine secretion	GO Biological Process Annotations 2023	1.0	null
GSE195568_3_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SKGT2	DepMap CRISPR Gene Dependency	1.0	3.13321
BRD-K47598052_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
496100519_HIP_probable Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21048
posteroventral (inferior) parietal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11131
CRCGN016_MCF10A.WT.HP_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.13024
ACTL6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
Lung squamous cell carcinoma_LUSC_TCGA-34-5241-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_ZM 447439_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0172336
GDE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04192
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
secretory vesicle	GO Cellular Component Annotations 2025	1.0	null
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lisuride-6682	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HA130	DeepCoverMOA Drug Mechanisms of Action	-1.0	-2.74
r9 part of trigeminal transition zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05733
cloxacillin-7483	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
IFNA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00554923
UCKL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00498218
CP in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.73009
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A68D-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6509-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-M51239075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46308
inner CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.889659
Perturb_8535_KD_Rbfox1/Rbfox3_SRP062242	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.6319
SUZ12-27294783-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Vermiform appendix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.396087
BRD-K29198371_JAS07_003_HT29_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE163240_2_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02873
GSE139975_3_v_0_rnf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
guanethidine-5731	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEC50B	DepMap CRISPR Gene Dependency	1.0	2.25732
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96593
Prostate adenocarcinoma_PRAD_TCGA-CH-5753-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKMEL5	BioGPS Cell Line Gene Expression Profiles	1.0	0.939378
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
A549_AT9283_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0075391
digoxigenin-4680	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68174511_torin-2_MCF10A_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
rectum	HPA Tissue Protein Expression Profiles	1.0	0.777364
layer 1 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36606
CHMP4A	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M6-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WFG7-1226-SM-4LMK2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.956298
GTEX-S4Q7-1526-SM-3K2AG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.892719
BRD-K83718139	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10367
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K59491482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27899
ISCU	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27935
AA-23-FM46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.957905
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33249
Prelimbic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02405
sirolimus-921	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A45498368_WYE-125132_SKBR3_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
plasma membrane part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042876
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0266
TCFAP2C-20176728-TROPHOBLAST-STEM-CELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE65617_2_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-8660-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Capecitabine_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126393
SUZ12	ENCODE Transcription Factor Targets	1.0	null
BE-27-XF09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.417791
arteriosclerosis	GWASdb SNP-Disease Associations	1.0	1.33606
BRD-K22651517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09313
PFEIFFER	CCLE Cell Line Gene CNV Profiles	1.0	1.36248
BRD-K33775409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12045
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5191
3-acetylcoumarin-4664	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45069
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.861632
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.956394
regulation of postsynaptic neurotransmitter receptor endocytosis	SynGO Synaptic Gene Annotations	1.0	null
KYSE-520	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.950116
Acute Myeloid Leukemia_LAML_TCGA-AB-2987-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
16-phenyltetranorprostaglandin E2-7509	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
BRD-K40175214_torin-1_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH1650	DepMap CRISPR Gene Dependency	1.0	4.27254
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-7979-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09411
GSE216043_3_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
isoxicam-7028	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A97Q-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPL-0008-SM-4E3I9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930976
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
haloperidol-1024	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.82434
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
amrinone-4488	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIGLEC9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00784931
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857208
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.672283
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PRPF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.82798
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01108
BRD-K49328571_dasatinib_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.18966
GTEX-S7PM-0008-SM-3NM9Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47851
furazolidone-4098	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
anisomycin-2658	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
neurotransmitter transport	GO Biological Process Annotations 2015	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EX-A8YF-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3226433-1756-8935-4-20-S1.XLS-Table_S4_Myc_KD_gene_exp_change-Genes_down-regulated_in_Myc_KD_hESC_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20653
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.458288
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858703
MYC_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A98714080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47433
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.937464
BRD-K29415052_NVP-BGT226_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KB-78-BE93_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.380721
GSE206729_4_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K59317601_INK-128_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC6420765-12864_2019_5550_MOESM4_ESM.xlsx-R_D9_vs_D15-Row_names_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
esr1_21713035_mcf7_lof_human_gpl570_gds4061	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-2.73653
EJM	CCLE Cell Line Gene CNV Profiles	1.0	1.64447
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-A4C9-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZC-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
testis	HPA Tissue Protein Expression Profiles	1.0	0.777364
CD14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00504166
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAPKAPK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00455251
triamcinolone-5835	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.36617
inner CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.849794
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0426-SM-2S1PU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
paravermis of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.994624
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.327195
BRD-K52139780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14403
KMS26	CCLE Cell Line Gene CNV Profiles	1.0	1.51539
Sarcoma_SARC_TCGA-SI-A71P-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
forebrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.32205
GSE211177,GSE211178_8_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cinnarizine-3175	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10572
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vesicle organization	GO Biological Process Annotations 2015	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Lapatinib_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139741
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60775
GTEX-XQ3S-0926-SM-4BOPI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837858
UPCISCC200	DepMap CRISPR Gene Dependency	1.0	4.65277
GSE218580_1_v_4_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0008-SM-48U2D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34233
Postsynapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
BRD-K74129999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09783
BRD-K31462164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57612
dorsolateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33611
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.3427
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51319
POLR2A_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC1	DepMap CRISPR Gene Dependency	1.0	2.31879
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:N17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03895
transport	GO Biological Process Annotations 2015	1.0	null
AE-39-DG66_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.283468
CD22	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00673591
valproic acid-1647	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
median eminence	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.405935
11-deoxy-16,16-dimethylprostaglandin E2-7519	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TFAP2C_01_312	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.64911
BRD-K71357636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40537
organism form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051857
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.961806
Median nucleus of thalamus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.02
BRD-K44371786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17549
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VA-48-RJ44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206073
Perturb_12297_OE_TMEM33_SRP322205	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
PMC8500868-401_2021_2354_MOESM5_ESM.xlsx-GEP_PATZ1-Gene_Symbol_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.55813
A-Vietnam-1203-2004(H5N1)_7Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.24816
GSE111247_11_v_1_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22931
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
LANCL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70356
LLC-PK1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
Sarcoma_SARC_TCGA-QQ-A8VB-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8015-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.35613
SGK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00503022
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0081
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebral lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.468436
A549_BRD4770_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.015018
non-neuronal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.454512
DA-35-DU85_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.457175
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LEF1-29337183-MESC-MOUSE-STEM	ChEA Transcription Factor Targets 2022	1.0	null
A549_Bisindolylmaleimide IX_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161861
BATF	ENCODE Transcription Factor Targets	1.0	null
GSE186633_2_v_0_chd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.906688
disease	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
BRD-K55836749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09374
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	84.67
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-0008-SM-4LVN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32447
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
A549_Resveratrol_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0190335
PIK3AP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00555116
GSE77108_6_v_7_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924067
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5798892-41421_2017_3_MOESM7_ESM.xlsx-Veh_KO_vs_WT-Supplementary_Table_S2-1_Up-_and_downregulated_genes_in_ATF6_cells_relative_to_ATF6_cells_in_the_presence_of_Vehicle_early_passage_ATF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10022
GTEX-TMZS-0008-SM-47JWM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37858
hl60	HPA Cell Line Gene Expression Profiles	-1.0	-0.826749
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KCNK12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00311136
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-CEBPB_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
0198306-0000-7099	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
clemastine-7443	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23907
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	1.0	null
niclosamide-4018	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE205729,GSE205731_2_v_1_tazemetostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A18328003_GDC-0980_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SF1	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE229973_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Resveratrol_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0151521
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
coronary artery disease	GWASdb SNP-Disease Associations	1.0	1.33606
abnormality of the respiratory system	GWASdb SNP-Phenotype Associations	1.0	0.099189
PRAG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00737563
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19L-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VJ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09511
UCMA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19035
membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045009
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Amacrine cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69328504_L-690,488_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38128
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.868939
WNT7A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0072189
BF-97-LS55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.228728
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.82999
GSE166315_2_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
capan2	HPA Cell Line Gene Expression Profiles	1.0	0.883236
GSE139016_3_v_2_disulfiram_human	RummaGEO Drug Perturbation Signatures	-1.0	null
blood vessel	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.05551
GTEX-SNOS-0008-SM-4DM6I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
BRD-K02708799_GSK-1059615_MCF10A_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K68174511_torin-2_SKBR3_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
medial part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07623
GSE236228_0_v_1_penfluridol_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72328
DJ-1_KD_GDS3750_373_human_SH-SY5Y	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
chr16_19382436_C_T_b38	GTEx eQTL 2025	1.0	4.96684
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
QE-79-XO29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.365938
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.08039
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041053
Cell junction	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
GTEX-Q2AG-0008-SM-48U2K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
CE-96-GH46_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.45646
FF-22-NB12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213586
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K38975326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60268
Ca9-22	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51653
vascular system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054554
Amygdala	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.0676
BRD-K51228600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34341
GSE188870,GSE188871_4_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0152
USF2	ENCODE Transcription Factor Targets	1.0	null
PMC10158025-ijbsv19p2081s6.xlsx-SupTable5-ZBTB20_ZBTB20	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K56536691	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40208
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
UQCRC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02343
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K94803981	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18484
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.924661
A549_JNJ-7706621_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.013519
GSE222758_0_v_2_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28286
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8352-01A-31R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202434,GSE202438_13_v_1_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8QA-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
metal ion binding	GO Molecular Function Annotations 2015	1.0	null
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.202122
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.84833
HDAC2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20114
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.24214
MOLM16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63031
PMC2813300-pone.0008960.s011.xls-SOX2_squamous_signature-Gene_Symbol_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anion binding	GO Molecular Function Annotations 2015	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24376
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039154
MAP2K4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30376
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.949933
GSE173873_8_v_11_stra8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868396
A-CA-04-2009(H1N1)_Day1_22532695_GSE36328	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.34441
hsa-miR-4501	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GSE205070_1_v_4_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233048
BE-42-IC00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25807
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10243915-uxad037_suppl_supplementary_table_s1b-table_s3b.pdf-167-SALL4_SALL4	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HW-7491-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K16485616_mocetinostat_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23318
PMC6938365-pone.0226733.s020.txt--ESR1_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4308
NCI-H1650	GDSC Cell Line Gene Expression Profiles	1.0	1.54573
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3PL-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.87543
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CD248	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00670334
BRD-K46994278	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09367
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A82E-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
A549_Tie2 kinase inhibitor_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0185248
calcium ion sensor activity	GO Molecular Function Annotations 2025	1.0	null
GTEX-NL4W-0011-R5a-SM-2I3GD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862068
GSE217378_2_v_0_lin28b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YY1	ENCODE Transcription Factor Targets	1.0	null
abnormality of bone marrow cell morphology	GWASdb SNP-Phenotype Associations	1.0	0.21137
BRD-K49865102_PD-0325901_MCF7_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MK-886-601	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882319
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RW-A681-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GJB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00475481
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.1655
GSE211177,GSE211178_8_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:I12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.3041
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.16795
GTEX-XMK1-1026-SM-4B65H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969028
Prostate adenocarcinoma_PRAD_TCGA-HC-7232-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OLIG2-26023283-AINV15-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1I8-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFKBID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05203
Piriform area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0724
ZFP90	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00586647
cerebellar cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.886039
SEPTIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0751
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC9290241-13058_2022_1547_MOESM2_ESM.xlsx-Foglio1-Supplementary_Table_S1_Differentially_expressed_transcripts_in_common_between_EPZ-_and_MI-2-treated_MCF-7_cells_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
central nervous system disease	GWASdb SNP-Disease Associations	1.0	0.107635
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A0YR-01A-12R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K52104866	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32545
Perturb_8514_KO_Setd1b_SRP328849	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.05051
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.991621
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SR-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_Pracinostat_1然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0112446
GSE126345_4_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
A549_Decitabine_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146498
NKX3-2	JASPAR Predicted Transcription Factor Targets	1.0	null
chloropyrazine-6227	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
epithelial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051685
A549_Enzastaurin_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0164799
establishment of organelle localization	GO Biological Process Annotations 2015	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39X-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAMLD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0044491
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.259343
A549_Tacedinaline_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.022331
GTEX-RVPU-0008-SM-3NM8B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29916
single-organism cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-RN64-0008-SM-48FEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10217
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.905286
GTEX-S7SF-0008-SM-3NM8T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
A549_KW-2449_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0199507
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Postpiriform transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34545
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.07457
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40579
limbic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.426872
SRSF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00637159
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925211
GSE130401_4_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02271
CRCGN015_MCF10A_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.90058
GSE201239_3_v_4_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE142210_2_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.30471
GFAP_OE_GDS1488_255_mouse_Olfactory bulb of  4 month old	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ELK1	ENCODE Transcription Factor Targets	1.0	null
BICR6	DepMap CRISPR Gene Dependency	1.0	3.39862
LCK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0064025
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.00046
A549_Amisulpride_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0240654
anterior olfactory nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.946947
496100445_HIP_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.12041
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15202
GSE211286_4_v_6_tcf12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39601
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SW837	DepMap CRISPR Gene Dependency	1.0	3.43083
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LPCAT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.005902
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
heliotrine-3717	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T5JC-2126-SM-32PMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30801
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976127
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-PN-A8MA-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-3.40597
ethoxyquin-4321	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310604
SLCO1B3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00658967
GSE172458_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.976457
ChIP_H3K9me3_19884255_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-ZG-A8QY-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
sulfadiazine-1810	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.07919
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.971889
PANC0327	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40421
BRD-K20755323_-666_NCIH596_6.0_h_40.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.628302
gabapentin-7229	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
3-nitropropionic acid-6407	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K50140147_NVP-TAE684_HT29_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.69989
USF1	ENCODE Transcription Factor Targets	1.0	null
Inferior olivary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.98
GSE84148,GSE96938_0_v_2_nrros_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Prednisone_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131415
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.981498
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ7-mel	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51955
PMC10081388-media-2.xlsx-ST12-Unnamed_7_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08044
BRD-K77908580_entinostat_HA1E_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-8012-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOP-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895739
AE-42-HT01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25791
ESR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233145
BRD-K94580242	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00974
hair-cell stereocilium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.979
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.8549
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.686013
Postpiriform transition area, layers 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53105
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SHANK3_KD_GDS4759_338_mouse_E16 primary cortical neuron cultures	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE-15-RO34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.257959
regulation of secretion	GO Biological Process Annotations 2015	1.0	null
PRDM1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K59000636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09429
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Agranular insular area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16226
ASH2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58569
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0126
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MS-2625-SM-3LK77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32597
BRD-K77175907_DM-100_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.981976
amygdaloid complex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.906519
GTEX-OOBK-0008-SM-3NB27	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17707
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43948
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.87159
abnormality of the breast	GWASdb SNP-Phenotype Associations	1.0	0.394985
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3NI-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A74Q-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
homosalate-4533	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AU565	DepMap CRISPR Gene Dependency	1.0	2.02477
BRD-K57472585	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33485
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0283
ND-68-CU31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260239
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.499
A549_BRD4770_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0185384
CRCGN016_MCF10A.TP53.M_24H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.26638
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
estradiol_homo sapiens_gpl6947_gse27375	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PAX2	JASPAR Predicted Transcription Factor Targets	1.0	null
REM sleep behavior disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.106
PNPLA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28749
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYO5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4564
golgi apparatus part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.070591
GTEX-PWOO-2326-SM-2S1PQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849131
Pancreatic adenocarcinoma_PAAD_TCGA-LB-A7SX-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102505_1_v_2_tunicamycin_human	RummaGEO Drug Perturbation Signatures	1.0	null
AB-85-JR73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.284545
CRCGN014_HEPG2_24H:A22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0032
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIA_Deficiency_GDS2775_640_mouse_Postnatal brains (at P16)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7995-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
abnormality of nervous system physiology	GWASdb SNP-Phenotype Associations	1.0	0.063465
thyroid gland	HPA Tissue Protein Expression Profiles	1.0	0.777364
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14852
BRD-K34581968_BMS-536924_VCAP_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SELE	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00618572
PMC12179407-MCO2-6-e70261-s004.xlsx-up_TET3-KO_PQ_vs_Cas9_PQ-Unnamed_10_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K37687095_AZD-8330_MCF10A_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE157050,GSE157051_2_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN008_HEPG2_24H:H14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1309
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23902
KDM5B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00351174
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44755
GSE147283_1_v_3_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Flavopiridol HCl_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0228526
GSE150349_0_v_1_msx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9490101-mmc3.xlsx-Sheet1-Supplementary_Table_3_Differentially_expressed_genes_in_CASC11_KD_MHCC-97H_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Iniparib_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155952
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r9 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38199
H3K27me3_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9590125-40478_2022_1453_MOESM3_ESM.xlsx-NEUN_UNIQUE_DYS_GENES-PAX6_TLE_vs_TL_log2FoldChange_1_padj_0_1_PAX6	Rummagene Transcription Factor Associations 2026	1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:A19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11848
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
temporal pole, right, inferior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.869106
BRD-K34122000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22071
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.829129
GSE86507,GSE86509_7_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QEG4-0008-SM-48TYZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
BRD-K51454923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26546
A549_2-Methoxyestradiol_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0186916
YBEY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6745
GSE94814_2_v_3_reck_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dentate gyrus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1716
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.849801
BRD-K19220233_JNK-9L_MCF10A_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EZH2_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218378_1_v_0_pbx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130437_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
u251mg	HPA Cell Line Gene Expression Profiles	-1.0	-0.826749
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.14401
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5430-01A-02R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of dendrite extension	GO Biological Process Annotations 2023	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-5248-01A-01R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
REG4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00605773
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
A549_JQ1_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0134715
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64182
tanespimycin-5919	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
abnormal hemoglobin	GWASdb SNP-Phenotype Associations	1.0	0.581386
ALDH1A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00443863
TB-06-VB30_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215779
PMC7291745-12967_2020_2407_MOESM2_ESM.xlsx-Table_S1D_CCF_pairs-locus_PITX1	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SA-01A-21R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-3026-SM-48U1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55156
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-7521-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.0045
estradiol-1666	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE116810_5_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-REY6-2126-SM-48FD9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895823
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE128730_0_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K49865102_PD-0325901_HT29_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K92195351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15031
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.88956
SPINK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0057889
OB-20-LP90_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.736078
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RB-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
olfactory lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.603295
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_SETDB1_19884255	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MOLP-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825506
ANKIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10412
CRCGN016_MCF10A.WT.HP_24H:G15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.12266
BRD-K96968070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00459
clathrin binding	GO Molecular Function Annotations 2015	1.0	null
GA-88-CF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.355942
crotamiton-5689	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.890285
MCF7_CUDC-907_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00963371
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC4006	CCLE Cell Line Gene CNV Profiles	1.0	1.46978
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0258
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.925695
diencephalon	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.219047
GSE146982_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K76984291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88693
GTEX-U8XE-0008-SM-4E3K4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12586
GTEX-XMD1-0011-R8A-SM-4AT48	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26824
GSE206729_2_v_0_trps1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE131377_1_v_0_spocd1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EFNA1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00577169
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nasopharynx	HPA Tissue Protein Expression Profiles	1.0	0.777364
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917061
BRD-K18149487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92978
H3K27me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0011-R8A-SM-447C7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20824
A549_Clevudine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156036
BRD-K30917841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87779
BRD-K63271817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00393
PMC7397849-supp_gad.338681.120_Supplemental_Table_S3.xlsx-S3L_Peaks_2SA-YAP1_TEAD4-Unnamed_11_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MAX_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53414658_tivozanib_A375_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
positive regulation of cell growth	GO Biological Process Annotations 2023	1.0	null
r7 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13495
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13043
RING1B-27294783-CHIP-SEQ-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
calcium-ion regulated exocytosis	GO Biological Process Annotations 2023	1.0	null
outer CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.938956
A549_Fasudil_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152716
renal tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.148469
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_4day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.70088
BRD-K49328571_dasatinib_HS578T_3_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K26074237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43599
Ebolavirus(EBOV)_5day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.01358
GTEX-S7SE-0008-SM-33HB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6994-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CFL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00754817
primary motor cortex (area M1, area 4)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.976531
duodenum	HPA Tissue Protein Expression Profiles	1.0	0.777364
BRD-K94012289_OSI-027_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE126345_0_v_10_hcrt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A47109850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34902
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-0008-SM-447AY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.951335
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.8563
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4834-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	2.54421
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34545
infundibulum	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.388535
TTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2419
P2RY2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00836233
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.94117
CRCGN015_MCF10A_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.33882
GTEX-S4Z8-0008-SM-33HAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21952
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.908867
Cecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_M344_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129367
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day14-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
NOC3L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01611
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K75815721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57586
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV44-0008-SM-447AX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
TRAIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00516192
BRD-K06678077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11067
Paraventricular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.023
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70E-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00608821
peripheral portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3266
A549_S3I-201_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0153946
Axon collateral	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.56
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EVPL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12457
eye	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063152
ACSM2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00617696
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cortical amygdalar area, posterior part, medial zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20482
HDAC2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
clozapine-1009	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
golgi apparatus part	GO Cellular Component Annotations 2015	1.0	null
GSE175787_13_v_6_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.910144
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BMAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14407
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.558383
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9038526-mmc1.xlsx-postCOVID_LPS_vs_healthy_L-symbols_98_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U4B1-1626-SM-3DB8N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877425
acenocoumarol-2077	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CF-61-EH59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20229
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03611
Kidney renal papillary cell carcinoma_KIRP_TCGA-EV-5902-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-AF-4110-01A-02R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.58296
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.02787
IGFN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00602174
synapse part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7111
19225562-TableS1	GeneSigDB Published Gene Signatures	1.0	null
layer 2 of AOD cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40927
Ovarian cystadenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22329
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25653
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.382
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41311
GSE112860_5_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.39546
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ING4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23839
superficial stratum of LPrP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14914
20368555-TS-1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02125
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-6225-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE193351_1_v_9_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
exocytosis	GO Biological Process Annotations 2015	1.0	null
GSE258991_1_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary somatosensory area, lower limb, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0318
GSE242647_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.264764
subcommissural organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.05413
AC-05-MR83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.509171
TIA1_KO_GSE54418_260_mouse_cerebellum	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
superficial stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40744
ependymal epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.196167
calcium ion binding	GO Molecular Function Annotations 2015	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.13758
layer 2 of LPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12728
carbarsone-3250	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A549_Trichostatin A_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126985
Dorsal peduncular area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.88202
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.2101
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52469
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Eosinophil Count Procedure	DisGeNET Gene-Phenotype Associations	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A3GN-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12571248	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15627
Dendritic branch	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.127
D-3263	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.27
GTEX-X88G-0008-SM-47JWN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852232
A549_TMP195_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0219913
HUWE1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00493903
etilefrine-4590	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE138863_3_v_0_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F5-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC6879454-Data_Sheet_1.xlsx-AA_in_vitro-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
JHOS4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41875
BRD-K04426746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2215
KB-72-ID36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.308629
NCIH1568	DepMap CRISPR Gene Dependency	1.0	2.39891
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE261177_0_v_1_tnfrsf12a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TFCP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8829
GW4064	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.23
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50377
GTEX-S341-0008-SM-4AD6D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17664
BRD-K45819372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16965
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6392-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.52303
phenazopyridine-5758	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cholesterol, LDL	dbGAP Gene-Trait Associations	1.0	0.478993
rnf2_20805357_megakaryocytic_l8057_lof_mouse_gpl1261_gse33659	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.015474
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
IA-76-ZU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.268191
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6366-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
A549_WP1066_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0132909
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
abnormality of carbohydrate metabolism/homeostasis	GWASdb SNP-Phenotype Associations	1.0	0.194188
BRD-K44344720	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26268
outer CP in posterosuperior (dorsal) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09594
BRD-K09951645_dabrafenib_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K76115264	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11215
OccipitalLobe	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.32522
icSARS CoV_48Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.30597
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71671
SUZ12-20075857-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
COV644	DepMap CRISPR Gene Dependency	1.0	2.17811
TFAP2C	ChEA Transcription Factor Targets	1.0	null
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prelimbic area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22934
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_cardiac mesoderm_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NLRP3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00529009
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE134375_0_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
20068109-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
single-organism organelle organization	GO Biological Process Annotations 2015	1.0	null
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824756
PTPRT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00838563
GSE121319_1_v_0_gprc5a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.904727
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.480652
K2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.864923
BRD-K59657378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54536
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95323025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16882
cerebral cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.388535
GTEX-P44H-0008-SM-48TDW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848158
BRD-K82135108_elesclomol_PL21_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Synapse	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
salivary gland	HPA Tissue Protein Expression Profiles	1.0	0.777364
Terminal bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.155
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.28967
NCI-SNU-16	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.6575
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49905
FC-20-EQ58_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.48929
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19407
A549_ABT-737_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0201661
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_EED226_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0236513
ChIP_REST_21632747	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
19061838-TableS3	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_Penis Foreskin Fibroblast Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
spanning component of plasma membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.246769
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.5338
CTCF_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2GZ-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Diethylstilbestrol	DeepCoverMOA Drug Mechanisms of Action	1.0	0.55
abnormality of the genitourinary system	GWASdb SNP-Phenotype Associations	1.0	0.059041
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESR1-26153859-T47D-HUMAN-BREAST-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K42918627_GSK-2126458_LNCAP_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COX7C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00583124
PAX5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
BRD-K67535324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18511
eye and adnexa disease	GWASdb SNP-Disease Associations	1.0	0.116148
BRD-K18621941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11177
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.017
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20471
delsoline-6075	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Infralimbic area, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45146
DYRK1A	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GSE134375_0_v_7_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2029	CCLE Cell Line Gene Expression Profiles	1.0	1.58494
Subiculum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.819
GTEX-OXRL-0008-SM-3NB29	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28978
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42329
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A4ZB-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MT-1026-SM-3TW8T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30077
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.41126
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06405
olfactory bulb	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.605306
UACC257	DepMap CRISPR Gene Dependency	1.0	4.02844
NKX2-1_01_67	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.67676
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146072_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PDE-9i	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.4
SP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.989506
BRD-A25736793_everolimus_A375_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.543901
YA-78-MS95_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.563612
BRD-K49630774	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0443
GC-04-UF36_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.368811
FOXM1	ENCODE Transcription Factor Targets	1.0	null
GSE146982_3_v_2_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
adiphenine-7279	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Adipose Nuclei	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.91814
Perturb_4302_KO_Serpine1_SRP179032	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.19502
Rectum adenocarcinoma_READ_TCGA-AG-3725-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21296995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05917
BRD-K00685640	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01106
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16094
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08869
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40617
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3	ENCODE Transcription Factor Targets	1.0	null
FB-66-UU47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.849582
quinostatin-865	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UQCRH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14086
LANCL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00954571
genistein-1015	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ADAMTS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30152
orofacial cleft	GWASdb SNP-Disease Associations	1.0	1.04096
BRD-K13057245	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50738
GSE229973_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lycorine-4365	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7022
F11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00582107
GSE234289_4_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PF-00562151-00-6863	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
amygdaloid complex_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12363
H3K27me3_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nb4	HPA Cell Line Gene Expression Profiles	-1.0	-0.826749
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.0168
DA-69-UN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.269621
H3K27me3_cardiac mesoderm_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MET_knockout_251_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.75448
GTEX-UPK5-0008-SM-4IHJD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16576
GSE207832_1_v_0_usp22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21883
Prostate adenocarcinoma_PRAD_TCGA-YL-A8HL-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00540784
ENAM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00435606
HE-80-BQ08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.341611
SKNDZ	CCLE Cell Line Gene Expression Profiles	1.0	1.35497
Brain Lower Grade Glioma_LGG_TCGA-FG-A87N-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.847561
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.3271
BRD-K37919122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2915
hsa-miR-335-5p	MiRTarBase microRNA Targets	1.0	null
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991674
GSE193258,GSE193259_2_v_6_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GOSR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09264
GSE135030_8_v_5_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TA-19-YA45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214621
PMC6853299-pbio.3000476.s011.xlsx-Fig_4A-RA_812_genes_expression_ratio_in_ZF_and_OF_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
EIF3B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85865
NCIH1437	CCLE Cell Line Gene Expression Profiles	1.0	1.59743
SRSF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16085
BRD-K61831307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2159
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01024
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary	HPA Tissue Gene Expression Profiles	-1.0	-0.853589
Exocytic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.637
A549_Azacitidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0192367
Sarcoma_SARC_TCGA-DX-A48R-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE163240_3_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
cholesterol, ldl	GAD Gene-Disease Associations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A6MF-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAP2K1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10988
GSE191037_0_v_1_itraconazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36039
H3K27me3_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.6886
pivampicillin-5046	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
18794137-SuppTable1c	GeneSigDB Published Gene Signatures	1.0	null
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
nucleus of diagonal band	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.942363
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57795803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29402
SA-53-XG95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.372678
A549_Decitabine_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0133484
mantle zone of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05754
MYC	ENCODE Transcription Factor Targets	1.0	null
PAPOLA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00586505
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
u2197	HPA Cell Line Gene Expression Profiles	-1.0	-0.826749
Cortical amygdalar area, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14914
Dentate gyrus, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85794
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AA-23-FM46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.674398
Pars compacta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.934
lmo4_17452977_mcf7_lof_human_gpl570_gds2789	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.450116
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE182680,GSE182683_0_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
KCNK5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00666872
NKX2-1_01_66	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.85249
AD-51-FB60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263002
capsular epithelium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.351485
Gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
LUDLU1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.3352
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	74.5262
ERI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00588251
Artery - Coronary	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.739121
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27366
acetylsalicylic acid-984	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE148321,GSE169423_0_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K56426074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51559
CUX1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
EF-80-OD07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.376073
tretinoin-991	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.19301
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02951
BRD-K83190598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34492
NDUFA7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00596671
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Gly-His-Lys-6560	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.62244
SKG-IIIA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837768
Subcommissural organ	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.099
ERR2 (ESRRB)	MotifMap Predicted Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE230744,GSE237803_5_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_CUDC-101_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155299
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
t70-white-adipose_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.126
GSE200388_0_v_1_gemin5_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAD21_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QXCU-0008-SM-48FCH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
PD-70-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.935495
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.91116
MYCN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.6042
BRD-K06284373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10952
GSE200099_3_v_1_honokiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-P4PP-0008-SM-48TDV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54392
H3K4me2_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PRSS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00603063
BRD-K61726189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21309
CP-690334-01-4558	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.00332
BRD-K63547380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19042
496100380_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03808
PWP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03851
BRD-K81418486_vorinostat_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XUJ4-2626-SM-4BOQ3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862094
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.312755
LEMD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40087
CRCGN016_MCF10A.WT.HP_24H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.22531
GSE146982_7_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
16293578-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19603
BRD-K09186807_KIN001-244_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ALDH4A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51944
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983653
midbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.388158
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-HT-7677-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YIPF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05182
Anterior olfactory nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.165
GSE247775_1_v_0_tmprss2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139016_0_v_1_disulfiram_human	RummaGEO Drug Perturbation Signatures	1.0	null
abnormality of head or neck	GWASdb SNP-Phenotype Associations	1.0	0.115975
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239844_11_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
inner CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.896521
GSAP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523138
GSE147876,GSE147877_2_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K04968881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08151
valproic acid-1078	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE230656_0_v_1_gsdmd_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HD-51-KD29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.447703
tanespimycin-5586	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
k562	HPA Cell Line Gene Expression Profiles	-1.0	-0.826749
GTEX-S95S-1426-SM-2XCDM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.884882
SMC3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.897778
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8E-GENE_LIST_UPLOADED_TO_ENRICHR_MNT_KO_3T3_ONLY_2084_GENES_MNT	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K88573743_A443654_PC3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FB-66-UU47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.472286
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.966703
COPD - Chronic obstructive pulmonary disease_Bronchial epithelium_GSE3320	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	2.20991
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K03470412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34395
RUNX3	ENCODE Transcription Factor Targets	1.0	null
A549_Maraviroc_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145296
Ventral posterolateral nucleus of the thalamus, parvicellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57534
GTEX-Q2AG-0011-R8A-SM-2HMK5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.846375
mantle zone of r10BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05472
Entorhinal area, medial part, ventral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04948
GTEX-PWCY-0008-SM-48TE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33743
GSE238018_3_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10075
Appendicular lean mass	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.43979
OPM-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7953-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29009
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
neurohypophysis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.312595
GOLGA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01849
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCAD_KO_GDS4546_422_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.976127
HC-74-HM63_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320009
BRD-K92093830_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cancer	GWASdb SNP-Disease Associations	1.0	0.061843
Lung squamous cell carcinoma_LUSC_TCGA-92-8063-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
QA-07-KC40_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.423091
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2842-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
epivincamine-4500	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
r3 part of dorsal cochlear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02883
SW 48	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912621
BRD-K26291134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11968
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	79.6279
pindolol-2075	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881372
BRD-K64800655_PHA-793887_HCC515_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE199204,GSE211619_4_v_7_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
regulation of cellular localization	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6394-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.917484
Proximal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.113
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-3_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
intermediate part of r10B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05282
GSE147876,GSE147877_2_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
LE-40-JW92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.441152
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
synapse	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
FOXA1_01_105	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	0.79704
carbohydrate metabolism disease	GWASdb SNP-Disease Associations	1.0	0.280495
ULK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00662559
MXI1	ENCODE Transcription Factor Targets	1.0	null
Distal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.834
nicergoline-5775	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
developmental disorder of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
GAD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00598337
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97921
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4A-Supplemental_Table_S4A_Differentially_expressed_genes_upon_ZFX_Knock_down_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
SKAP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00538599
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_BMS-911543_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0130323
r9 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29245
cholesterol	GAD Gene-Disease Associations	1.0	null
BRD-K02708799_GSK-1059615_A549_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K28195874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03195
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49967
PMC3470785-NIHMS377161-supplement-3.pdf-188-BHLHB8_BHLHA15	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00689
GSE148096_1_v_0_erlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
single-organism transport	GO Biological Process Annotations 2015	1.0	null
BRD-K35897342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08507
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29S-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-0008-SM-4BOQI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54083
increased pulmonary respiratory rate	MGI Mouse Phenotype Associations 2023	1.0	null
GTEX-QLQ7-0008-SM-447AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.894281
BRD-A45498368_WYE-125132_A549_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Ventromedial hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.818
A549_Selisistat_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154583
NLN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00584641
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55766625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06303
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2227	GDSC Cell Line Gene Expression Profiles	1.0	1.42096
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6875
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.001513
PFDN2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00632269
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231891_5_v_4_cdk8_human	RummaGEO Gene Perturbation Signatures	1.0	null
NTRK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00450114
etamsylate-4399	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC10771438-41598_2023_51082_MOESM1_ESM.xlsx-Day21-Supplementary_Dataset_1_List_of_genes_differentially_expressed_during_NS_PC_differentiation_between_ROR2_KD_cells_and_control_cells_AR	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of the IG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0759
Radial spoke head	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.516
BRD-K50190949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28604
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.926632
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Fruit consumption	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
BRD-K00337317_NU-7441_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K69932463_AZD-8055_MCF10A_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K94582731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59418
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Amisulpride_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0204495
GSE205550,GSE205552_2_v_3_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BD-69-XG81_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226859
GSE180185_9_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9161725-Table_4.xlsx-EHF-CSAG1_EHF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28243
BRD-K80700417_SGI-1776_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE206729_3_v_1_trps1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NL4W-0008-SM-4E3I2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04707
IC-05-AW29_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.292377
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Orbital area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15956
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7335061-41467_2020_17150_MOESM4_ESM.xlsx-Table_S3-LIN28B_correlates_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
spiradoline-4553	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K68174511_torin-2_MCF10A_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ERA-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
A549_Ruxolitinib_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167722
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909029
increased pulmonary respiratory rate	IMPC Knockout Mouse Phenotypes	1.0	null
GSE111660_4_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Prelimbic area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03614
Rectum adenocarcinoma_READ_TCGA-G5-6641-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168697_0_v_1_wdr6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
single-organism membrane organization	GO Biological Process Annotations 2015	1.0	null
BRD-K20526256_HG-14-10-04_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5791-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12801_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Maraviroc_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0171803
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212745
Lung adenocarcinoma_LUAD_TCGA-86-7711-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.942067
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41517
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.34857
oval paracentral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45754
PDCD10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00855183
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53505
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
A549_Vandetanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142446
HAMP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00589788
neurodegenerative disease	GWASdb SNP-Disease Associations	1.0	0.295671
BRD-K75331656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1699
GSE230744,GSE237803_0_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
digoxigenin-5640	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
pirenzepine-7226	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
regulation of neurotransmitter levels	GO Biological Process Annotations 2015	1.0	null
BRD-K83972459_JWE-035_HT29_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE109140_2_v_1_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QB-88-PG52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.366496
HEC50B	CCLE Cell Line Gene CNV Profiles	1.0	1.60618
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
GTEX-WFG7-0008-SM-4LMKB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35632
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825096
GB-57-XV52_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.29171
Perturb_11911_KD_Arntl2_SRP063609	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
KDM5A	ENCODE Transcription Factor Targets	1.0	null
vesicle	GO Cellular Component Annotations 2015	1.0	null
GSE184902_3_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_CUDC-101_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0179015
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HS578T	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.924618
inferolateral temporal cortex (area TEv, area 20)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.884912
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960839
GSE165647_2_v_3_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7SE-0011-R1A-SM-2XCDE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40549
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.185
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319375
(+)-isoprenaline-5009	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
tanespimycin-4442	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NR1D1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9161
BRD-K77483143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38836
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.984505
MCF-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.98874
BRD-K40175214_torin-1_SKBR3_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8561673-NIHMS1742950-supplement-Table_S7.xlsx-Housekeeping_MYC_ProxTubGenes-Proximal_Tubule_Enriched_Genes_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K49328571_dasatinib_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
pheochromocytoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.522405
BRD-K12145385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09141
Orbital area, medial part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0963
pergolide-7434	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Sarcoma_SARC_TCGA-IE-A3OV-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AC-41-IB85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204032
GSE94849_7_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
DYRK4	Kinase Library Serine Threonine Kinome Atlas	1.0	null
GTEX-P4QT-0008-SM-48TDZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16667
GSE167324_2_v_0_eif4e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PSME3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68104
H3K27me3_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A4NE-01A-11R-A27V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326844
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
PRDM1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.5475
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
organelle part	GO Cellular Component Annotations 2015	1.0	null
BRD-A45498368_HY-10044_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCIH660	CCLE Cell Line Gene Expression Profiles	1.0	1.62015
BRD-K40175214_torin-1_MCF10A_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K55147629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47565
GTEX-XUZC-0008-SM-4BOQG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3019
CRCGN016_MCF10A.WT.HP_24H:K10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.0035
CyPPA	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.43
UBAC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14038
dorsomedial hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.896149
medial (fastigial) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45006
intracellular part	GO Cellular Component Annotations 2015	1.0	null
H3K4me1_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
primidone-5323	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A549_WHI-P154_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0178484
FBXO32	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00681264
diprophylline-1811	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JSC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
19204204-SupplementaryTable2	GeneSigDB Published Gene Signatures	1.0	null
A549_Tucidinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.012532
CAL78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63735
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
signal release	GO Biological Process Annotations 2015	1.0	null
A549_WHI-P154_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0138592
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K09191212_MLS-0091943.0001_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
dorsolateral part of Int	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22384
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19827
harmol-7320	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36775
NF-21-HQ00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217078
midbrain reticular formation	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.883899
BRD-K43389698_BMS-387032_BT20_24_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Crus II, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.934865
BRD-K34664417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03059
SIN3B	ChEA Transcription Factor Targets	1.0	null
RCC10RGB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
EXOC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70117
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Mesna_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149044
PMC12499388-ADVS-12-e01774-s002.xlsx-Table_S1-Table_S1_Differentially_Expressed_Genes_between_wild-type_and_TET3-knockout_PANC-1_cells_TET3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147876,GSE147877_4_v_9_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
5186223-885	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23318
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31059261	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1686
PMC12882559-12894_2026_2046_MOESM2_ESM.docx-0-ZNF770_ZNF770	Rummagene Transcription Factor Associations 2026	1.0	null
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.885762
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
nerve	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064023
BRD-K83815133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44661
GSE76425_0_v_12_lenalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AB-71-CI37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.470921
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.03496
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
EE-03-SG02_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.759872
CRCGN015_MCF10A_48H:L01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.5466
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.099173
AD-06-OB47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.558333
REXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06929
lidocaine-1499	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Substantia innominata	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.751
Lung adenocarcinoma_LUAD_TCGA-49-4514-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
estropipate-4472	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
piromidic acid-4575	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27me3_H7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	HPA Tissue Gene Expression Profiles	1.0	1.68555
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA-73-BW50_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.26711
sulfadiazine-5523	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-78-7163-01A-12R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
E2F7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00630145
TMEM266	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00616646
HMGB1P1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79852
GTEX-TKQ1-0008-SM-4DXSO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16115
CRCGN015_HEPG2_48H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13414
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5418
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-downregulated_in_ATF4OE-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
Zygotene cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.703
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.18066
IL13RA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0049999
PMC8791933-41598_2022_4817_MOESM4_ESM.xlsx-PAX7_up-Unnamed_1_PAX7	Rummagene Transcription Factor Associations 2026	1.0	null
A549_PFI-1_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172304
intermediate part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22115
testis_7d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.07815
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.491854
syntaxin binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-QMRM-0008-SM-447B1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
BRD-K33940145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28329
abnormality of the cardiovascular system	GWASdb SNP-Phenotype Associations	1.0	0.581386
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15132
BRD-A60245366_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Ileocecum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
dihydrostreptomycin-2074	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JAK2_activemutant_72_GSE21842	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.19837
Perturb_1112_KO_Vcan_SRP167386	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.89501
QA-07-KC40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.35081
CREM	ChEA Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52859
CRCGN015_MCF10A_48H:P20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.25347
abnormality of the mouth	GWASdb SNP-Phenotype Associations	1.0	0.177696
SEC13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11388
NCI-H510A	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
EGLN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00507841
levodopa-4571	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
G415	DepMap CRISPR Gene Dependency	1.0	3.80448
A549_FLLL32_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156322
Prestwick-857-4980	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TGFB1I1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00574573
estradiol-6968	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE168233_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Glesatinib(MGCD265)_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.01477
ellipticine-5779	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE142210_4_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
disease of mental health	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063671
RPS13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16154
meteneprost-7504	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
neoplasm	GWASdb SNP-Phenotype Associations	1.0	0.074879
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K17850764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05084
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pervasive developmental disorder	DISEASES Experimental Gene-Disease Association Evidence Scores	1.0	0.368757
NF-21-HQ00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270669
BRD-K31883990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38101
tobacco use disorder	GAD Gene-Disease Associations	1.0	null
excretory gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095934
adrenal medulla	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.444884
TAAR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00759199
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE222758_0_v_1_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.82434
REST-18959480-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
XPOT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00519319
AD-51-LE62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21137
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19373
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.13634
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49865102_PD-0325901_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SPDEF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00511281
superficial stratum of m2B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03614
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
amygdalohippocampal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32345
Rectum adenocarcinoma_READ_TCGA-CL-5917-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
AFF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01342
BRD-K21025364_NVP-TAE226_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RSBN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00578624
GSE181461_1_v_4_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
AA-48-XT80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.833755
Hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.341
NPPB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00462417
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ACADM_KO_GDS4546_512_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Perturb_202_KO_Carmil3_SRP168358	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.883142
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
HC-74-HM63_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.403708
BT549	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.897861
NANOG	ChEA Transcription Factor Targets	1.0	null
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN016_MCF10A.TP53.M_24H:D18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.13178
H3K27me3_cardiac mesoderm_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pancuronium bromide-4393	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN008_HEPG2_24H:L13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9413
GTEX-SNMC-0926-SM-4DM5U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01067
BRD-K61791241	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2706
pars compacta	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.565232
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A18328003_GDC-0980_SKBR3_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Abnormalities, Drug-Induced	CTD Gene-Disease Associations	1.0	1.35415
A549_Capecitabine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146963
monorden-4443	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PAT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.152
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.38667
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.24286
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
A549_Tozasertib_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0249003
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23737
BRD-K52441396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19291
Lung adenocarcinoma_LUAD_TCGA-50-5932-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25485483	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42822
BRD-K12787259_CX-5461_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE142210_9_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K49865102_PD-0325901_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
mRNA_POU5F1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
abnormality of the upper urinary tract	GWASdb SNP-Phenotype Associations	1.0	0.128899
hindbrain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.317315
H3K36me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.04283
kidney disease	GWASdb SNP-Disease Associations	1.0	0.678541
PMC6683136-41598_2019_47363_MOESM4_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039012
BRD-K93785828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7783
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.4845
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.918521
KMH-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14983_KO_Hdac2_SRP097585	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.46501
PMC8494348-pone.0257161.s002.xlsx-D20-NOT_ext_ext-NOT_ext-Gene_Name_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T5JC-0626-SM-3NMA6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04631
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.36777
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23457
VA-92-QP54_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.495252
LRRC37A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00551557
RPS5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.55147
KDM1B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00517649
GSE126345_7_v_5_hcrt_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE193351_1_v_2_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SHROOM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39434
Anterior olfactory nucleus, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57084
PMC3435504-msb201237-s2.xls-Supp_Table_4a-WT1_WT1	Rummagene Transcription Factor Associations 2026	1.0	null
MA-06-DJ95_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.360948
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.31889
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OHPK-0008-SM-4E3JL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11027
Synaptic vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.622
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
r10 basal plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31295
RAD21_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thiamphenicol-7033	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Endo_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K45734366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4769
hsa-miR-3665	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
guanabenz-4642	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K75745696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93187
Retrosplenial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.99
GTEX-XXEK-0526-SM-4BRWD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.868993
6-bromoindirubin-3'-oxime-7048	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18385
FE-10-KQ78_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.787077
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25722
CREB1	ENCODE Transcription Factor Targets	1.0	null
CCDC85B	Pathway Commons Protein-Protein Interactions	1.0	null
GSE138672_0_v_1_rabgef1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Transport vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.583
A549_Barasertib_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0113
establishment of localization in cell	GO Biological Process Annotations 2015	1.0	null
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52630978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03032
A549_ITSA-1_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0254975
cisplatin_mus musculus_gpl339_gse6206	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0026
Perturb_15081_KD_Crebbp_SRP354984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.308
mediodorsal nucleus of thalamus_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.829129
cellular response to salt	GO Biological Process Annotations 2023	1.0	null
cyanocobalamin-4572	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K22674439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9279
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.380232
GSE169263_1_v_0_armc5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BAD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00579958
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.40241
Leukemialymphoblastic(MOLT-4)	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.930531
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EZH2_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parkinson's disease	GWASdb SNP-Disease Associations	1.0	0.787271
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GABP-19822575-HEPG2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
sirolimus_homo sapiens_gpl2895_gse16944	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.899782
pilocarpine-6741	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
r10 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40559
CHAMP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49036
BRD4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00542347
GSE228181_3_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MALME3M	CCLE Cell Line Gene CNV Profiles	1.0	2.59998
ChIP_NANOG_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K02827191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33322
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11062
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.37411
Mesothelioma_MESO_TCGA-LK-A4NZ-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-IW-A3M5-01A-22R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BC-13-OQ01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.366036
H3K23me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
adrenal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.21883
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF343	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.3642
posteroventral (inferior) parietal cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.837136
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.8872
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03813
UPCISCC154	DepMap CRISPR Gene Dependency	1.0	2.40249
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.47562
BRD-K81418486_vorinostat_SW948_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XBED-0008-SM-47JWO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
SUM225CWN	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.512521
BRD-K58607444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0082
BRD-K49328571_dasatinib_A375_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CAKI-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.63672
BRD-K18190982_COT-10b_RKO_6.0_h_44.4000015259_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
synaptic vesicle exocytosis	GO Biological Process Annotations 2015	1.0	null
GABP-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
sirolimus-4445	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213410_2_v_3_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ZS-A9CF-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CDC25C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00728314
Neurosecretory cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.564
A549_Aminoglutethimide_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014954
TEAD4	ENCODE Transcription Factor Targets	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Endo_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K51385533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78673
GSE142210_9_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27me3_Brain Germinal Matrix	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K02708799_GSK-1059615_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE214596,GSE214598_1_v_0_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Somatosensory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.06
GSE190681_1_v_0_rtcb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-K80483148	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41117
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.00095
S0-EE-Y7IR_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.304326
Dorsal peduncular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49962
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.042394
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02043
MYOD1_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FEN1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00513743
ESS-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56183302	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42409
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEPG2	CCLE Cell Line Gene CNV Profiles	1.0	1.63569
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE242083,GSE242098_2_v_5_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Excitatory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.285
vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CD93	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00550923
GSE135030_8_v_9_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
SLC22A3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00685544
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148695,GSE167284_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11871363-41598_2025_89344_MOESM1_ESM.pdf-15-NR5A2_NR5A2	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of calcium ion-dependent exocytosis	GO Biological Process Annotations 2023	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.885549
GEM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0056079
HDAC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00456482
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7288-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LY-294002-6987	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.04256
RIOX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10082
biological_process	GO Biological Process Annotations 2015	1.0	null
GSE178907_5_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PPARD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8484
CRCGN008_HEPG2_24H:O14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16005
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Y-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K13350372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34456
A549_Valproic acid sodium salt_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0222586
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.61546
A549_JNJ-26854165_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0160228
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63556
wortmannin-1023	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.4774
A549_Bisindolylmaleimide IX_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0212404
mc2	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.769
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.902865
mantle zone of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07361
GTEX-T6MN-0011-R2A-SM-32QOW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27151
sirolimus-1045	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K20437312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3397
DA-58-LZ09_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.311838
SETDB1	ChEA Transcription Factor Targets	1.0	null
Gall bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-T5JC-0011-R2A-SM-32PLZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924889
DNM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24405
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.303
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.16586
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9692021-Table_4.xlsx-Table_S4-Table_S4_405_DEGs_of_RA_synovial_tissues_between_NFIL3-high_and_NFIL3-low_group_NFIL3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
terazosin-6092	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AC-76-JB92_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.206846
NCIH1048	CCLE Cell Line Gene CNV Profiles	-1.0	-2.46781
GABPB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00764913
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840355
trans-golgi network	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
CHD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00510544
SAMHD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0039196
Lung adenocarcinoma_LUAD_TCGA-55-A4DG-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205163,GSE205164_3_v_4_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIH1395	CCLE Cell Line Gene CNV Profiles	1.0	1.43414
BRD-K21025364_NVP-TAE226_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
DB-28-SP20_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.318246
medial nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.904968
lipid binding	GO Molecular Function Annotations 2015	1.0	null
m1 part of parabrachialis pigmentosus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53555
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85021
CRCGN013_HEPG2_24H:B17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2511
Inflammation	CTD Gene-Disease Associations	1.0	1.0561
GSE145249_0_v_2_ppm1g_human	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7055-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cytoplasmic vesicle	GO Cellular Component Annotations 2015	1.0	null
BRD-K72800151	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09797
GTEX-TSE9-0011-R10A-SM-3DB7O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996542
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
AMPD1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00668348
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Ltk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.316
cinchonine-2789	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC6488738-mmc6.xlsx-TCF12-Target_Gene_TCF12	Rummagene Transcription Factor Associations 2026	1.0	null
hippocampus (hippocampal formation)_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.973227
AKT_UP_MTOR_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
GH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00854477
PMC9894241-pnas.2211429119.sd05.xlsx-G4_REST-Dataset_S6_Differentially_expressed_genes_in_G1-G8_REST	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10742386-pnas.2311372120.sd05.xlsx-GCM1_EVT-Gene_Symbol_GCM1	Rummagene Transcription Factor Associations 2026	1.0	null
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.027
H3K27me3_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNB19	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.830431
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
abnormal eye morphology	GWASdb SNP-Phenotype Associations	1.0	0.116293
A549_Ki8751_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0197999
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-0008-SM-4DXT2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
Body Height	DisGeNET Gene-Phenotype Associations	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.96809
amodiaquine-5747	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-A4BW-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.35411
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92767663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11715
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46708
RAD21_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV31-0008-SM-447AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
18381933-SuppTableS4	GeneSigDB Published Gene Signatures	1.0	null
single-organism membrane fusion	GO Biological Process Annotations 2015	1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HB-06-WU12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.562197
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.43068
GSE81803,GSE81912_2_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ADIPOR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16473
TCF12	ENCODE Transcription Factor Targets	1.0	null
GTEX-Q2AI-0008-SM-48U2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36768
GSE226983_2_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Tucidinostat_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128716
17699763-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300633
GSE229973_4_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ovarian serous cystadenocarcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.032
BRD-A06352508_SB 218078_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19168792-TableS3	GeneSigDB Published Gene Signatures	1.0	null
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K50058129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09933
GSE142210_3_v_5_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
superficial stratum of TTe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04498
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K93357133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19204
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E7-01A-31R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic membrane-bounded vesicle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
establishment of localization	GO Biological Process Annotations 2015	1.0	null
Perturb_15226_OE_hIGFBP5_SRP337748	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-7.07631
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DCTD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02552
LA-42-ER00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.704187
CRCGN008_HEPG2_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1511
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Zona incerta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.588
Smoking Behaviors	DisGeNET Gene-Phenotype Associations	1.0	null
brain	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.260606
tanycyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.934482
BRD-K17649115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.265
SF3B5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28552
H3K27me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r10 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93097
ILDR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00608092
nalbuphine-2063	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K99252563_QL-XII-47_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8512-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10528072-NIHMS1928302-supplement-5.xlsx-ASCL1-target_genes-ABAT_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0963
Acute Myeloid Leukemia_LAML_TCGA-AB-2861-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
cyclobenzaprine-4252	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
regulation of transport	GO Biological Process Annotations 2015	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
SAA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00709037
GA-88-CF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.462973
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27506
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.853263
PMC13082837-NIHMS2159075-supplement-3.xlsx-DataTable5_Methylation_LMS-UCSC_RefGene_Name_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.825506
BRD-K54751614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82549
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25141
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53284
calcium ion binding	GO Molecular Function Annotations 2023	1.0	null
temporal pole, left, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.885319
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Entorhinal area, lateral part, layer 2a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10114
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
hydroflumethiazide-1809	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GRIA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00701175
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA1_01_233	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.83926
GSE147876,GSE147877_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57455
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Primary dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.07
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.848035
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.7968
BRD-K86817746	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18796
GTEX-NPJ8-0011-R3a-SM-2HMIW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03266
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.23178
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.20313
abnormality of the nervous system	GWASdb SNP-Phenotype Associations	1.0	0.044769
disease of metabolism	GWASdb SNP-Disease Associations	1.0	0.21472
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.168
positive regulation of developmental growth	GO Biological Process Annotations 2023	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PSG5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00595805
retinal disease	GWASdb SNP-Disease Associations	1.0	0.678541
NUR77	MotifMap Predicted Transcription Factor Targets	1.0	null
KA-29-AB08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22409
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
fenbufen-3618	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
inherited metabolic disorder	GWASdb SNP-Disease Associations	1.0	0.278619
RPP25L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08116
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-2.50446
regulation of dendrite extension	GO Biological Process Annotations 2025	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.840355
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900336
GTEX-XMD1-0008-SM-4AT41	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16395
GSE154074_1_v_0_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PAS complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.682
r9 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.70549
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28251
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58173
BRD-K60132279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27
BRD-K76068355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50136
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.886969
BRD-A19037878_trichostatin A_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.5555
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K91917132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08205
BRD-K29415052_NVP-BGT226_HT29_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_ITSA-1_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0119018
GSE214212_2_v_0_chd6_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K09594570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32264
A549_Rucaparib_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120908
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18277965-TableS1b	GeneSigDB Published Gene Signatures	1.0	null
GSE205630_0_v_1_gmds_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914051
MERO48A	DepMap CRISPR Gene Dependency	1.0	4.10586
NR3C1-23031785-PC12-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ANAPC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.20458
MMAC-SF	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47861
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LY334370	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.35
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5274-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Perturb_2481_Mut_ESR1_SRP254635	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
indometacin-503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MNDA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00547393
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC4784386__F5	PFOCR Pathway Figure Associations 2023	1.0	null
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.05446
HUP-T3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.5284
Adrenocortical carcinoma_ACC_TCGA-OR-A5JQ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K12460934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04021
GTEX-U412-0008-SM-4DXTE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34677
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K86856088_UNC0638_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VL-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40949
A549_Ruxolitinib_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128914
GTEX-P4QR-0008-SM-48TE2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890585
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8189-01B-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70193997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18484
cerebellar nuclei of CbV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44856
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0988
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05282
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.831459
where	GeneRIF Biological Term Annotations	1.0	null
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SUZ12-20075857-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Linifanib_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0126326
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vesicle fusion	GO Biological Process Annotations 2015	1.0	null
Salivary_Gland-ionocyte	Tabula Sapiens Gene-Cell Associations	1.0	0.160823
HSPBAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17619
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.443978
BRD-K08799216_pelitinib_SKBR3_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PHA-00846566E-7046	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IX	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08433
mantle zone of r10BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.57075
BRD-K69932463_AZD-8055_MCF10A_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GUCY2F	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00592356
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.82745
Pancreatic adenocarcinoma_PAAD_TCGA-HZ-8519-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_Givinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00920718
urogenital system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064586
retina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.089107
BRD-K31716785	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28578
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883094
CRTC3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00455742
PMC9061835-41523_2022_425_MOESM1_ESM.xlsx-S3_Differential_GEX-Table-S3_Differential_expression_analysis_results_for_SOX10-high_versus_SOX10-low_TNBCs_from_the_TGCA_and_METABRIC_expression_datasets_SOX10	Rummagene Transcription Factor Associations 2026	1.0	null
calcium-dependent phospholipid binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-OIZH-1626-SM-2HMKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26497
GTEX-T5JC-2526-SM-4DM6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12938
intermediate stratum of DG	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43205
GTEX-PLZ6-1126-SM-3P5ZR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24457
BRD-K02708799_GSK-1059615_HCC515_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72Z-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
terbutaline-5764	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
A549_Sorafenib Tosylate_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.016959
outer CP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03631
brain_3c	HPA Tissue Sample Gene Expression Profiles	1.0	1.74501
KC-32-GO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.280476
KP3	CCLE Cell Line Gene CNV Profiles	1.0	1.33161
H3K27me3_H7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K27me3_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain - Hypothalamus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.685768
HMV-II	COSMIC Cell Line Gene Mutation Profiles	1.0	null
betazole-1812	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NCIH1105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.42738
BRD-K94012289_OSI-027_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A61G-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Blood Coagulation Disorders	CTD Gene-Disease Associations	1.0	1.09857
BRD-K07781811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09427
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A59Y-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865284
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE207728,GSE207808_2_v_1_c646_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH1436	CCLE Cell Line Gene Expression Profiles	1.0	2.35098
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.97212
diethylstilbestrol_rattus norvegicus_gpl1355_brown norway_gds2913	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.213291
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05346
BRD-K73126584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05351
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74327
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09643
lung cancer	GWASdb SNP-Disease Associations	1.0	0.55831
cingulate gyrus, frontal part, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.892893
BRD-K99749624_S1003_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE216352,GSE216354_1_v_0_keap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.39546
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.063668
VA-48-RJ44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204502
mRNA_SALL4_19060217	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
MEF2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.7224
BRD-K67868012_PI-103_MCF10A_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K82181189_ischemin_HCC515_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A549_Momelotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137578
IFNA4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00724935
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.11587
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PPARA_agonist activation_GSE17251_474_human_Isolated hepatocytes	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12177
mantle zone of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22519
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.634735
CB-16-SY72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.335034
Abnormalities, Multiple	CTD Gene-Disease Associations	1.0	1.03752
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUCB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93537
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10699
H3K9ac_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K69093885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41784
BA-72-YP01_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24126
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52076
MMP17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00683081
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.278763
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.93548
GSE152666,GSE152668_2_v_1_carm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE193351_1_v_3_ruxolitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
outer CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.861291
RAD21_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RAD21_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_6_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
acetylsalicylic acid-4428	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6935-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PPARD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00331772
GSE135514_2_v_9_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
sensory system disease	GWASdb SNP-Disease Associations	1.0	0.096571
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.9436
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06084
crotamiton-3388	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Nicotine dependence	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.201
A549_Hesperadin_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0132868
BRD-K72833997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04935
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF354A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	185.008
GSE133764_1_v_0_chd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Breast Neoplasms	dbGAP Gene-Trait Associations	1.0	0.22418
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12385
MYOG	ENCODE Transcription Factor Targets	1.0	null
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-U60236422_WH-4-025_HS578T_3_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040713
5286656-889	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K29395450_PIK-93_HCC515_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Cell body fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.15
regulated exocytosis	GO Biological Process Annotations 2023	1.0	null