association dataset threshold value standardized value BRD-K37564297 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15481 ventral posteromedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.18802 ZNF157 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.9869 MELJUSO DepMap CRISPR Gene Dependency 1.0 2.24797 CRCGN016_MCF10A.WT.HP_24H:C20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.29534 Anterior olfactory nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.47803 H3K27me3_Adipose Nuclei Roadmap Epigenomics Histone Modification Site Profiles 1.0 null Ventral anterior-lateral complex of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02037 SCC-9 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00858 inner CP in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.43535 POU2F1::SOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.3516 CRCGN016_MCF10A.TP53.M_24H:P20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.00413 BRD-K65752097 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25843 BRD-K73210450 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.0388 r9 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47642 H3K27me3_CD4+ CD25- Th Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.248361 Intrinsic component of cell outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.938 anterior hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.08719 Pulvinus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.833 pontine raphe nucleus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.95645 BRD-K49148914 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44382 layer 3 of AOV cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.39894 cerebellar cortex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.15877 Foxo1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 16.951 Glucose metabolism disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.485 TRIM28_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null ventromedial hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01043 HNF1B JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.6914 BRD-K72173400 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19557 BRD-K18004653 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.9104 dorsolateral prefrontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.24004 SG in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.85052 CRCGN015_MCF10A_48H:J24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.32355 periventricular mantle of isBM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16654 single-organism process GO Biological Process Annotations 2015 1.0 null Major depressive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.174 SKMM2 CCLE Cell Line Gene CNV Profiles -1.0 -1.35854 SF767 CCLE Cell Line Gene Expression Profiles -1.0 -1.86185 plicamycin LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.86163 PMC3573729-nl3042917_si_005.xlsx-OWY_Overlap_with_ANOVA-ORKIN_DAX1_NR0B1 Rummagene Transcription Factor Associations 2026 1.0 null TE14 CCLE Cell Line Gene CNV Profiles 1.0 1.43696 open GeneRIF Biological Term Annotations 1.0 null BRD-K33606963 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05303 pharmacological GeneRIF Biological Term Annotations 1.0 null medial part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46765 Generalized epilepsy with febrile seizures plus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.328 intercalate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06146 mantle zone of r10BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66323 ventral linear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31346 positive regulation of cyclase activity GO Biological Process Annotations 2015 1.0 null RXRA::VDR JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.0 Primary somatosensory area, upper limb, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06901 BRD-K48241951 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15657 BT-483 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.18852 Synaptic cleft COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.31 retroparafascicular area of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07326 BRD-K84348716 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.76407 UMC-11 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.81181 primary auditory cortex (core)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.44121 POU3F2 ChEA Transcription Factor Targets 1.0 null intermediate part of r7B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.5101 amygdaloid complex_3 yrs_M_12980 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.84302 BRD-K65438558 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.71534 striatum_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.89829 icSARA deltaORF6_48Hour_23365422_GSE33267 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.10178 CRCGN013_HEPG2_24H:H24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.8248 mantle zone of m2AD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00188 p1B part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.91104 Signaling by GPCR Reactome Pathways 2014 1.0 null NR0B1 ChEA Transcription Factor Targets 1.0 null BRD-K41169041 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44538 BRD-K58932103 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.40799 NCIH1299 CCLE Cell Line Gene CNV Profiles 1.0 1.5362 BRD-K72609226 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.32207 family GeneRIF Biological Term Annotations 1.0 null central amygdaloid nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12473 IZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32255 outer portion of medial ganglionic eminence Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.854535 POU5F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.5425 BRD-A97608543 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.50624 Muscle cell projection COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.615 NR0B1-18358816-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null Idiopathic fibrosing alveolitis_Lung Tissue_GSE21369 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 1.97592 TWIST1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.107 HNF4G JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2532 caudal subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.97475 HCN3 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.63789 metformin-4 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SNU-475 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.23711 striatal part of olfactory tuberculum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06219 BRD-K71420819 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.80371 GATA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.2393 HAND2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.4634 Zona incerta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1383 BRD-K92344227 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.09585 BRD-K69942587 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46953 BRD-K52083268 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16227 prasterone-3097 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null occipital pole, left, superior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.72281 CRCGN017_MCF10A.TP53.M_24H:I10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.59602 mRNA_AES_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null superficial stratum of r7BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29353 NUGC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.852638 nasal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.905831 BRD-K27948561 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10185 r8 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.4524 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4878-01A-01R-1305-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K22970494 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30533 BRD-K99000702 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06167 r7 part of trigeminal transition zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10343 intermediate part of StrSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08816 Deutocerebrum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.108 HS939T CCLE Cell Line Gene CNV Profiles -1.0 -1.45701 Coleoptile TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.934 U937 CCLE Cell Line Gene Expression Profiles 1.0 1.41319 GR MotifMap Predicted Transcription Factor Targets 1.0 null Arx JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.1787 positive regulation of nucleotide metabolic process GO Biological Process Annotations 2015 1.0 null BRD-K19712167 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05188 CRCGN016_MCF10A.TP53.M_24H:C19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.2563 ECI2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.27595 COLO678 CCLE Cell Line Gene CNV Profiles -1.0 -1.71241 MDN1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.44617 Antennal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.265 superior frontal gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.84583 FOXL1 JASPAR Predicted Transcription Factor Targets 1.0 null EKC/KEOPS complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.767 A-Vietnam-1203_CIP048_RG3-2004(H5N1)PB1-F2del_4day-MOI-10^4_None_GSE44441 GEO Signatures of Differentially Expressed Genes for Viral Infections 1.0 1.75832 mRNA_ESX1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null hippocampus (hippocampal formation)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.29336 NCI-H146 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34928 BRD-K45947503 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.62322 CRCGN015_MCF10A_48H:M16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.72315 positive regulation of metabolic process GO Biological Process Annotations 2015 1.0 null BRD-K88478877 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02157 BRD-K75584297 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.04686 CRCGN016_MCF10A.TP53.M_24H:O18 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.90171 LS123 CCLE Cell Line Gene CNV Profiles 1.0 1.57388 regulation of nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50243 BRD-K61134709 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01771 NEUROG2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 41.8232 lateral subdivision of BNST Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.5486 SCC9 DepMap CRISPR Gene Dependency 1.0 3.84416 HOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3987 A2780 CCLE Cell Line Gene CNV Profiles -1.0 -1.91994 CRCGN015_MCF10A_48H:C20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.10618 epithelial GeneRIF Biological Term Annotations 1.0 null BRD-K86995890 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.99252 Stat5a JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.3048 CRCGN015_MCF10A.TP53.M_24H:C07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.06205 P3HR1 CCLE Cell Line Gene Expression Profiles 1.0 3.32819 BRD-K86961579 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10983 SG in caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12745 H3K27me3_skeletal muscle myoblast_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null CRCGN017_MCF10A.WT.HP_24H:O19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.5147 intermediate stratum of r10Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37984 Nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.478 precentral gyrus, left, inferior lateral aspect of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.834167 diclazuril LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 6.59239 anterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.48952 Nr2e3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 15.0 Ensheathing process COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.974 BRD-K83180232 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.37893 specific GeneRIF Biological Term Annotations 1.0 null Paraventricular hypothalamic nucleus, magnocellular division, medial magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11159 lateral septal nucleus, intermedio-dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.08816 intrinsic component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.105834 FOSL2::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.4466 BRD-K40452322 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06938 r1 part of vestibular nucleus Y Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40948 Final leaf TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.5 BRD-K28559679 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.5849 CRCGN009_HEPG2_24H:L13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 10.0 MAFK CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.03955 Signal Transduction Reactome Pathways 2014 1.0 null GATA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.7085 respiratory system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.090151 CRCGN009_HEPG2_24H:K01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.96804 Obesity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.092 CFAP97 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.43278 RERF-LC-OK Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.34928 BRD-K70856965 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.14028 BRD-K95558029 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1582 U-2932 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33311 RI1 CCLE Cell Line Gene CNV Profiles -1.0 -1.68391 CRCGN015_MCF10A_48H:B10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.5802 DBTRG05MG CCLE Cell Line Gene Expression Profiles -1.0 -2.00773 BRD-K71538933 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.1658 SK-MEL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.889747 CRCGN017_MCF10A.WT.HP_24H:C19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.8526 T47D Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.30829 anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.908432 temporal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.23577 MZ in ventromedial extrastriate cortex (VP) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.992128 NCI-H1395 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.41996 SPIB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.6312 primary somatosensory cortex (area S1, areas 3,1,2)_23 yrs_M_12300 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.42338 CRCGN015_MCF10A.WT.HP_24H:C20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.67674 hypoglossal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.44707 parastrial preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23009 CRCGN017_MCF10A.WT.HP_24H:N17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.5422 BRD-K31197843 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.65227 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Distal-RefSeq_Name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null OCIAML2 Achilles Cell Line Gene Essentiality Profiles 1.0 1.66955 MOTN1 CCLE Cell Line Gene Expression Profiles 1.0 1.37144 Amylin receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.708 CRCGN017_MCF10A.WT.HP_24H:P08 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.6035 T3M4 BioGPS Cell Line Gene Expression Profiles 1.0 1.00694 H3K27me3_G1E-ER4_mm9_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null NFIL3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.5081 PMC11923433-BLOOD_BLD-2024-025618-mmc2.xlsx-S3_Specific_genes_in_CEBPA-dm-Supplemental_Table_3_The_subtype-specific_enriched_marker_genes_in_CEBPA-dm_subtype_patients_CEBPA Rummagene Transcription Factor Associations 2026 1.0 null SNU349 CCLE Cell Line Gene Expression Profiles -1.0 -2.50081 DOV13 CCLE Cell Line Gene CNV Profiles 1.0 1.40058 BRD-K92358687 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19204 subbrachial nucleus, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28033 regulation of purine nucleotide biosynthetic process GO Biological Process Annotations 2015 1.0 null Bipolar disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.352 cerebellar cortex_10 mos_M_12977 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.32896 BRD-K75224334 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29156 Crus I, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.829772 Anterior olfactory nucleus, medial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1185 Rectum adenocarcinoma_READ_TCGA-AF-3911-01A-01R-1736-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2279 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.921852 647-V GDSC Cell Line Gene Expression Profiles -1.0 -2.01829 BRD-K00767817 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.08337 regulation of primary metabolic process GO Biological Process Annotations 2015 1.0 null BRD-K43381631 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04501 Ventral globus pallidus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.856 IM-95 COSMIC Cell Line Gene Mutation Profiles 1.0 null NR4A2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1626 POU6F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.9646 BRD-K65488906 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11304 Schizoid personality disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.017 lateral part of r7B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0444 docebenone LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.36894 tanespimycin-432 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Vomeronasal nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.093 BRD-A05828965 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2998 HCC2998 BioGPS Cell Line Gene Expression Profiles -1.0 -2.8634 BRD-K28982281 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.9428 CRCGN012_HEPG2_24H:H24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.7965 Primary somatosensory area, upper limb, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11058 regulation of biosynthetic process GO Biological Process Annotations 2015 1.0 null BRD-K76389813 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06181 NCI-H1299 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.43994 BRD-K67150949 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1632 IZ in lateral temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.22858 Lateral root TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.55 nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.05065 Arrector pili muscle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.765 V, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.28471 BRD-K83254798 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.98987 BRD-K52887203 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08413 FOXC1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 32.7185 BRD-K64571715 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.58037 CRCGN015_MCF10A.TP53.M_24H:G13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.22925 CRCGN017_MCF10A.WT.HP_24H:P09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.1169 TYK-NU Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -2.2032 Inferior olivary complex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.23443 Acquired metabolic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.191 mantle zone of r10BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70064 Bam protein complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.938 BRD-A64985224 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13715 IMR-32 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.3561 Olfactory placode TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.103 imatinib_homo sapiens_gpl96_gds3044 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K07781811 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12044 Disease of anatomical entity DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.495 laterodorsal subdivision of area 8 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.02462 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4920-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null EZH2_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Medial septal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16057 SNU466 CCLE Cell Line Gene CNV Profiles -1.0 -1.32095 CRCGN015_MCF10A.WT.HP_24H:P17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.18763 OCILY19 CCLE Cell Line Gene CNV Profiles -1.0 -1.41308 HOP92 BioGPS Cell Line Gene Expression Profiles -1.0 -0.9875 HCC2885 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.881634 IZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.833978 OVKATE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28904 POU4F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.2415 FLI1-21867929-TH2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null KASUMI1 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.59215 BRD-K50677542 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39391 Germinated grain TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.942 Taenia tecta, dorsal part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04676 H3K4me3_retinal pigment epithelial cell_hg19_2 ENCODE Histone Modification Site Profiles 1.0 null Mitral cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.288 ZNF274 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.4481 Nucleus accumbens TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.484 amygdaloid complex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.908432 EVX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.2269 lateral hypothalamic area, anterior region, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.69481 intercalated nucleus of medulla Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.955867 496100622_HIP_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.00697 KMOE-2 COSMIC Cell Line Gene Mutation Profiles 1.0 null 721_B_lymphoblasts BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.16731 Piriform area TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.291 CRCGN015_MCF10A_48H:J10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.14781 primary auditory cortex (core)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03779 p3 part of the ZL core Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -3.03279 True leaf TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.868 IRF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 57.0 regulation of molecular function GO Biological Process Annotations 2015 1.0 null regulation of cellular process GO Biological Process Annotations 2015 1.0 null BRD-K51237617 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.30983 NMCG1 CCLE Cell Line Gene Expression Profiles -1.0 -1.83287 retrohypothalamic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.94098 SNUC2A CCLE Cell Line Gene CNV Profiles 1.0 1.34985 MYBL2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9257 imatinib_homo sapiens_gpl96_gds3045 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null H3K27me3_HeLa-S3_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-7502-01A-11R-2204-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Cotyledon TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.005 BRD-K71836501 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.38064 BRD-K59960811 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19119 molecular transducer activity GO Molecular Function Annotations 2015 1.0 null GAK GDSC Cell Line Gene Expression Profiles 1.0 1.45234 b69 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.673 RNF139 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55035 gigantocellular reticular nuclei Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.835487 BRD-K37989903 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.86611 Sox7 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.8902 mantle zone of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.13198 G alpha (s) signalling events Reactome Pathways 2014 1.0 null BRD-K77417197 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03585 Lateral root primordium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.709 496100570_HIP_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.98763 regulate GeneRIF Biological Term Annotations 1.0 null SK-MES-1 GDSC Cell Line Gene Expression Profiles 1.0 1.68391 BRD-K97391170 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.31779 KNS60 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.10437 BRD-K74794014 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.85071 BRD-K72700227 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01282 BRD-K89447678 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.77437 intermediate stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.88068 SCC15 CCLE Cell Line Gene CNV Profiles 1.0 3.02139 CRCGN017_MCF10A.WT.HP_24H:G15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.85975 SOX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.8379 periventricular stratum of m1B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43963 CDX2-19796622-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null r10 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66323 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2R9-01A-11R-A18M-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HUT78 CCLE Cell Line Gene CNV Profiles 1.0 1.7936 BRD-K00620786 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16872 imatinib_homo sapiens_gpl96_gds3042 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null FOXE1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 86.9335 JcP contribution to LTL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39216 SG in dorsomedial parietal cortex (area 7m) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.828421 SKNAS CCLE Cell Line Gene CNV Profiles -1.0 -1.63862 BRD-K30548577 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42632 layer 3 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45047 CRCGN011_HEPG2_24H:P03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.2979 layer IIIu of area 35r Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.66994 NCIH1623 CCLE Cell Line Gene CNV Profiles -1.0 -1.98049 lateral septal nucleus, intermediate part, periventricular Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10754 BRD-K61595867 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02484 Orbital area, lateral part, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.37568 trace-amine receptor activity GO Molecular Function Annotations 2015 1.0 null VIIIA, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.88547 SNU5 CCLE Cell Line Gene Expression Profiles 1.0 2.46012 GPCRs other WikiPathways Pathways 2024 1.0 null BRD-K76154866 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.74953 Parahippocampal region TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.671 BRD-K32451879 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.85707 integument TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.057933 A172 BioGPS Cell Line Gene Expression Profiles -1.0 -0.9875 positive regulation of adenylate cyclase activity involved in g-protein coupled receptor signaling pathway GO Biological Process Annotations 2015 1.0 null central medullary reticular group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.22542 BRD-K25638876 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42483 BRD-K94518115 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.267 taars GeneRIF Biological Term Annotations 1.0 null Unicellular trichome TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.858 paraventricular nucleus, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.41304 rhombomere 11 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04138 CA3 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.963617 frontal pole, right, inferior aspect Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.968762 dorsal preisthmic part of periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0003 PANC 02.03 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852025 SG in primary somatosensory cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.993486 Thymus BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.71259 posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0772 17823238-TableS5 GeneSigDB Published Gene Signatures 1.0 null BRD-K01615174 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1251 Caryopsis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.897 CRCGN013_HEPG2_24H:B07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.26781 Nucleus globosus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.721 CRCGN017_MCF10A.WT.HP_24H:C21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.85835 CRCGN015_MCF10A_48H:O10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.83595 short insular gyri, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.964556 BRD-K95343362 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04278 BRD-K47984776 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42967 polymorphic layer of rostral subiculum Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.41269 59M CCLE Cell Line Gene Expression Profiles -1.0 -2.32319 Bt TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.594 Foxj2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.4833 regulation of cellular metabolic process GO Biological Process Annotations 2015 1.0 null H3K4me1_brain_mm9_1 ENCODE Histone Modification Site Profiles 1.0 null Mood disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.703 sensory perception GO Biological Process Annotations 2015 1.0 null Prostate adenocarcinoma_PRAD_TCGA-J4-A67O-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null positive regulation of cellular process GO Biological Process Annotations 2015 1.0 null prilocaine-4284 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K26634905 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14761 gracile nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.34795 SOX6-21985497-MYOTUBES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null CRCGN017_MCF10A.WT.HP_24H:A21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.67845 Subparafascicular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.02107 FOXO6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.9247 RL952 CCLE Cell Line Gene CNV Profiles -1.0 -1.85069 serotonin-activated cation-selective channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.558 primary somatosensory cortex (area S1, areas 3,1,2)_15 yrs_M_12299 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.24746 psychotic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.641433 BRD-K44497547 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.36445 BRD-A34826857 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25035 SLR24 CCLE Cell Line Gene Expression Profiles -1.0 -2.35109 BRD-K69375224 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.7404 BRD-K78697404 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.62101 MZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.48266 BRD-K56842656 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1626 trochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.40464 NCI-H1882 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.19153 hippocampus (hippocampal formation)_4 mos_M_12296 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.922458 r10 part of the inferior olive Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.42567 HCA-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.91669 POU3F2-20337985-501MEL-HUMAN ChEA Transcription Factor Binding Site Profiles 1.0 null BRD-K06486611 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42745 mRNA_DLX3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null r10 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.52406 lateral nucleus of pulvinar Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10174 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-MY-A913-01A-11R-A37O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TRIM28 ENCODE Transcription Factor Targets 1.0 null NU-DUL-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33311 Class A/1 (Rhodopsin-like receptors) Reactome Pathways 2024 1.0 null MEIS2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.6824 CRCGN014_HEPG2_24H:F03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 8.06679 PL4 DepMap CRISPR Gene Dependency 1.0 7.23976 BRD-K41033343 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44073 GPCR downstream signaling Reactome Pathways 2014 1.0 null Paraventricular hypothalamic nucleus, descending division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22337 Olfactory tubercle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.261 OTX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7294 THOC2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.11415 HOXB4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7429 BRD-K36451640 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07527 NCI-H1435 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K47482563 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.92595 A1207 CCLE Cell Line Gene Expression Profiles -1.0 -1.93457 BRD-K85567359 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02411 PAX8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.5501 H3K4me1_liver_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null Disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.815 BRD-K98408839 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3376 Brain Lower Grade Glioma_LGG_TCGA-FG-6692-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null LUZP1-20508642-ESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.3969 PMC4521181-oncsis201520x8.pdf-149-RREB1_RREB1 Rummagene Transcription Factor Associations 2026 1.0 null CiliaryGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.877042 modulation GeneRIF Biological Term Annotations 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-EB-A6QY-01A-12R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN015_MCF10A_48H:P04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.92235 corticoid layer of TuStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.02891 BRD-K71177762 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11474 SNU-1040 COSMIC Cell Line Gene Mutation Profiles 1.0 null Paraventricular hypothalamic nucleus, descending division, lateral parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22434 Raphe nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.104 CRCGN017_MCF10A.WT.HP_24H:N16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.73435 lateral part of MPO Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12631 BRD-K06313694 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32399 FOXD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 88.4542 EZH2 ENCODE Transcription Factor Targets 1.0 null Plant vascular cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.026 BRD-K64665523 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.83092 cellular_component COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 orbital frontal cortex_30 yrs_F_12290 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.24746 GPCR ligand binding Reactome Pathways 2024 1.0 null BRD-K34721572 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.43749 Infralimbic area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30649 NCI-H1703 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.991088 Dissociative disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.028 COLO 206F Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.960137 NCI-H345 COSMIC Cell Line Gene Mutation Profiles 1.0 null Adductor TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.768 496100450_HIP_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.47158 BRD-K20347026 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.20148 medial portion of STH Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.16053 ventromedial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.36393 BRD-K38084509 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10464 Nfatc2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.5764 LASV_FML29 _4hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.45151 Tauopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.015 BRD-K96839404 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19683 Fibromyalgia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.166 amine GeneRIF Biological Term Annotations 1.0 null HCC38 DepMap CRISPR Gene Dependency 1.0 4.30903 anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.18971 Orbital area, ventrolateral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.21223 laterostriatal stripe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28109 PcPV part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03853 Metabolic disorders of biological oxidation enzymes Reactome Pathways 2014 1.0 null Respiratory mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.336 PMC11554977-40199_2024_523_MOESM2_ESM.xlsx-Sheet1-Supplement_2_Metformin_Drug_Sensitivity_and_Damaging_Mutation_by_using_PRISM_Repurposing_Primary_Screen_and_Damaging_Mutation_in_DepMap_PRDM6 Rummagene Transcription Factor Associations 2026 1.0 null Septohippocampal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.11079 ELK1::HOXB13 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2117 GA10 CCLE Cell Line Gene Expression Profiles 1.0 1.58982 nose TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.899871 BRD-K09975370 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0829 Amygdala TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.411 RAD21-21589869-MESC-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null CRCGN012_HEPG2_24H:G07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.58683 M14 COSMIC Cell Line Gene Mutation Profiles 1.0 null SK-HEP-1 GDSC Cell Line Gene Expression Profiles -1.0 -1.61145 GATA2-21186366-BM-HSCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null NCI-H1793 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.889747 ETS2 MotifMap Predicted Transcription Factor Targets 1.0 null CRCGN014_HEPG2_24H:N09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.82759 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RN-01A-11R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-S9-A7QW-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null HCC2814 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.8802 HS 940.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.56623 BRD-K43192646 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -5.64034 BRD-K31874013 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08177 r9 basal plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09363 RUNX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7572 g-protein coupled receptor activity GO Molecular Function Annotations 2015 1.0 null outer CP in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.896099 OCI-M1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.951667 Sensory cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.035 Subparafascicular nucleus, magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.05257 BRD-K17060750 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.03509 5g3 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.013 BRD-K68705041 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.93185 BRD-K95710843 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03596 HEC1A Achilles Cell Line Gene Essentiality Profiles 1.0 1.31122 HOXA5 JASPAR Predicted Transcription Factor Targets 1.0 null HCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.870386 496100554_FWM_no dementia_no TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.49372 BRD-K65108634 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00352 spinal trigeminal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13979 Orbital area, ventrolateral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.51864 DND-41 COSMIC Cell Line Gene Mutation Profiles 1.0 null GATA3_T47D_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K36539857 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.83661 BRD-A73618687 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.26807 BRD-K69624346 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.245 Anteroventral nucleus of thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.28341 NCI-H1650 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3051 Sensory dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.549 BRD-K16207499 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.18493 BRD-K30145193 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.62073 BRD-K76173551 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.02745 BRD-K47762331 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00592 PMC3573729-nl3042917_si_005.xlsx-OWY_Overlap_with_ANOVA-ORKIN_ESRRB_ESRRB Rummagene Transcription Factor Associations 2026 1.0 null HEP G2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.22083 Chemoreceptor cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.855 cell part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 r9 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.42155 BRD-K92524632 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.34626 MYC_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K66838288 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.03238 Orbital area, ventrolateral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00923 HCC1599 COSMIC Cell Line Gene Mutation Profiles 1.0 null MESSA CCLE Cell Line Gene CNV Profiles -1.0 -1.47354 BRD-K62152527 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.99097 Overnutrition DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.091 BRD-K35792251 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05767 MAX JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.6352 HCC1171 CCLE Cell Line Gene Expression Profiles -1.0 -1.67288 intermediate stratum of r10BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66426 BRD-K20024676 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.63093 CRCGN014_HEPG2_24H:A03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.63061 U20S BioGPS Cell Line Gene Expression Profiles -1.0 -0.9875 LASV_FML29_24hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.26281 lateral parabrachial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.834091 CRCGN017_MCF10A.WT.HP_24H:O15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.5159 BRD-K57879743 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.97023 inner SZ in superolateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.54025 CRCGN011_HEPG2_24H:G13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.701 BRD-K85873301 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.38303 BRD-K45986774 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17567 disease of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.278297 CRCGN016_MCF10A.TP53.M_24H:P14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.34618 piromidic acid-2996 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Apical dendrite COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.854 CRCGN014_HEPG2_24H:D07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.7295 intermediate part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.70115 X, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.971871 NCIH508 CCLE Cell Line Gene Expression Profiles 1.0 2.27055 NR0B1-18358816-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null regulation of cyclase activity GO Biological Process Annotations 2015 1.0 null Primary somatosensory area, upper limb, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03259 Thyroid follicle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.653 Internal plexiform layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.719 cellular_component LOCATE Predicted Protein Localization Annotations 1.0 null BRD-K84745303 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30389 primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.894773 BRD-K12513721 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53756 orbital frontal cortex_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.82435 CRCGN017_MCF10A.TP53.M_24H:P19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.18947 Anthranilate synthase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.204 NANOG ChEA Transcription Factor Targets 1.0 null NCI-H1869 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21611 BRD-K39824708 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.84745 Mecom JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 36.963 CRCGN014_HEPG2_3H:P03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.81695 hydroxytoluic-acid LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21844 FOS::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9421 Ciliary membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.903 496100367_FWM_no dementia_TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.71894 H3K27me3_G1E-ER4_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null RH30 DepMap CRISPR Gene Dependency 1.0 8.62883 Peripheral nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.949 Nfatc1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 20.5595 CRCGN017_MCF10A.WT.HP_24H:E04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.76638 Defective ACTH causes Obesity and Pro-opiomelanocortinin deficiency (POMCD) Reactome Pathways 2014 1.0 null signaling receptor activity GO Molecular Function Annotations 2015 1.0 null TM-4 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.932 TEAD2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.6458 BRD-K24929039 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05823 D502MG DepMap CRISPR Gene Dependency 1.0 2.63482 amygdaloid complex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0772 BRD-K15474464 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25198 CL11 CCLE Cell Line Gene CNV Profiles -1.0 -1.37742 H3K27me3_G1E_mm9_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null JHH7 CCLE Cell Line Gene Expression Profiles 1.0 1.82142 hsa-miR-335-5p MiRTarBase microRNA Targets 1.0 null TCF7L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.4484 plant-type vacuole COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.821 amygdaloid complex_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0282 Schizophrenia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.039 KYAE1 DepMap CRISPR Gene Dependency 1.0 3.30597 BRD-K22443456 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.58613 r9 part of the basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37984 NCO2 CCLE Cell Line Gene CNV Profiles 1.0 1.73639 POU2F1-35413990-HUMAN-ARPOSCRPROSTATECANCER ChEA Transcription Factor Targets 2022 1.0 null BRD-K64577556 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16133 lateral part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12299 superficial stratum of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.53371 BRD-K36104357 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17555 BRD-K49298555 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.07353 BRD-K00914921 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.00067 signal transduction GO Biological Process Annotations 2015 1.0 null Cognitive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.822 intermediate stratum of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54304 BRD-K59606563 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.05909 fastigial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.873782 regulation of adenylate cyclase activity GO Biological Process Annotations 2015 1.0 null CA2 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.907546 Pericycle TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.844 anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.15456 inferior olivary complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.29078 BRD-K53050301 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02964 L1TD1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.13293 NUGC-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.881634 BRD-K97878521 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.33164 SNU1105 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.10974 BRD-A04510218 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3103 Ventral tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.07719 KS1 CCLE Cell Line Gene Expression Profiles -1.0 -1.6016 plasma membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 nucleus of the inferior collicular brachium, caudal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.6845 BRD-K16304302 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.16011 intermediate stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.4524 dorsolateral prefrontal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.44521 BRD-K75981692 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.84396 oa1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.842 plasma membrane part GO Cellular Component Annotations 2015 1.0 null BRD-K28107038 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.70233 CRCGN016_MCF10A.TP53.M_24H:C10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.05343 OKAJIMA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.44146 K-562 COSMIC Cell Line Gene Mutation Profiles 1.0 null g-protein coupled receptor signaling pathway GO Biological Process Annotations 2015 1.0 null r1 part of intermediate nucleus of the lateral lemniscus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06863 Erg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 32.9185 ventral tegmental area Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.882744 BRD-K13204142 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02486 posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13421 FOXA1_T47D_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K27476975 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.41575 mediodorsal nucleus of thalamus_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.41678 BRD-K15690866 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04993 central nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.051003 STAT3_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4992-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null KARPAS-45 COSMIC Cell Line Gene Mutation Profiles 1.0 null Mitral cell layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.293 VIIIA, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.09004 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5201-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3MR-06A-11R-A21D-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null pedunculo(pontine) tegmental nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03876 head TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.302838 Ventromedial hypothalamic nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.595 anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.45259 medial group of nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.860355 FOXC2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.9747 CRCGN017_MCF10A.TP53.M_24H:A13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.72526 r10 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58792 EZH2_myotube_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null KMM1 CCLE Cell Line Gene Expression Profiles 1.0 1.38302 HS766T DepMap CRISPR Gene Dependency 1.0 2.74948 BRD-K14250524 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13982 CRCGN015_MCF10A_48H:G14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.7777 glycine-gated chloride channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.71 anterior pretectal nucleus, ventral superficial part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50487 BRD-K53548389 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.0259 amygdaloid complex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.63932 Neuroactive ligand-receptor interaction KEGG Pathways 2026 1.0 null A204 Achilles Cell Line Gene Essentiality Profiles 1.0 1.13853 Anterolateral visual area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1252 Prostate adenocarcinoma_PRAD_TCGA-EJ-A65G-01A-21R-A29R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BACH2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.1416 pyramidal layer of IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48479 NCIH1395 CCLE Cell Line Gene CNV Profiles -1.0 -2.32116 their GeneRIF Biological Term Annotations 1.0 null JHH1 CCLE Cell Line Gene Expression Profiles 1.0 1.80181 Migraine DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.54 HSF2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.7172 Human Immunodeficiency Virus DisGeNET Gene-Disease Associations 1.0 null TEF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.0055 CRCGN017_MCF10A.WT.HP_24H:O10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.11225 studies GeneRIF Biological Term Annotations 1.0 null MDAMB231 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.491392 NR4A1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.5459 HCC60 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.88481 BRD-K96560179 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.27623 A3KAW CCLE Cell Line Gene Expression Profiles 1.0 2.42951 Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Signaling by GPCR Reactome Pathways 2024 1.0 null Irritable bowel syndrome DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.072 NCI-H2347 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14763 periventricular stratum of RtC Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.94098 BARHL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.4643 CRCGN017_MCF10A.WT.HP_24H:N02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.49225 p2 part of the zona limitans core population Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.49985 SP in subgenual (subcallosal) cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.14432 BRD-K67556876 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11205 BRD-A29578214 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18017 NR1H2::RXRA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 31.08 L428 CCLE Cell Line Gene CNV Profiles 1.0 1.33088 Insular cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.829 positive regulation of adenylate cyclase activity GO Biological Process Annotations 2015 1.0 null Nanog JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.9618 CYBA CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.64775 ventrolateral prefrontal cortex_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.836936 TAL1-21186366-BM-HSCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null sense organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.336336 JHH7 CCLE Cell Line Gene CNV Profiles 1.0 1.70096 Primary visual area, layer 4 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02648 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RKO COSMIC Cell Line Gene Mutation Profiles 1.0 null stratum pyramidale of rostral CA2 Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10665 MDA MB435 BioGPS Cell Line Gene Expression Profiles 1.0 1.00694 Foxj3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 25.8163 cyclosporine_homo sapiens_gpl4133_gse25200 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null TP73 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.7333 17210682-SuppTable2 GeneSigDB Published Gene Signatures 1.0 null Locus ceruleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.092 BRD-K99331869 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36734 JHH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.15832 BRD-A57762296 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.18427 plasma membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.04317 BRD-K91241684 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19537 BRD-K66802550 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15926 grl101 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.661 COV504 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.870386 BRD-K12705251 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.52437 Parkinson's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.297 NANOG-18347094-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null el2 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.091 FOXK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.8371 BRD-K21443215 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16418 CRCGN016_MCF10A.TP53.M_24H:H09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.32066 MTF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5055 Arntl JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.5513 496100582_HIP_probable Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.5317 lateral orbital frontal cortex (area 12/47) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.2624 EVSA-T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.49046 membrane part GO Cellular Component Annotations 2015 1.0 null BRD-K72034681 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.50787 m1B part of the periaqueductal gray Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.43063 BRD-K23860926 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23742 AT6.1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.659 GFI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.7265 CAOV4 CCLE Cell Line Gene CNV Profiles -1.0 -1.50097 CRCGN009_HEPG2_24H:L08 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.1057 NCIH1355 DepMap CRISPR Gene Dependency 1.0 10.1692 positive regulation of phosphorus metabolic process GO Biological Process Annotations 2015 1.0 null paracentral lobule, posterior part, right, bank of cingulate sulcus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.44351 SP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.920728 Intrinsic component of periplasmic side of cell outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.938 MMAC-SF GDSC Cell Line Gene Expression Profiles -1.0 -1.54702 HLF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5785 cellular_component COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040382 EM2 DepMap CRISPR Gene Dependency 1.0 4.415 retroreuniens nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.26646 SMRT-22465074-MACROPHAGES-MOUSE ChEA Transcription Factor Targets 2022 1.0 null BRD-K97805186 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.47618 orbital frontal cortex_18 yrs_M_12984 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09411 Orbital area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.00857 microcellular tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00652 orbital frontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.31784 inner SZ in primary visual cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.12833 Periplasmic side of cell outer membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.938 ZBTB18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 43.8007 functions GeneRIF Biological Term Annotations 1.0 null CRCGN015_HEPG2_48H:O10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.49708 TYKNU CCLE Cell Line Gene CNV Profiles -1.0 -1.89755 HCT116 DepMap CRISPR Gene Dependency 1.0 5.91691 Node TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.691 intrinsic component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 Mo-B cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.916 Dux JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 36.7304 CRCGN015_MCF10A.TP53.M_24H:B10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.1991 Hippocampus minor TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.632 primary motor cortex (area M1, area 4)_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05817 Posterodorsal preoptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04064 Carbohydrate metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.489 SK-N-AS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37892 schizophrenia DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.643009 TOV-112D Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.852638 superior occipital gyrus, right, inferior bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.14634 G protein-coupled receptor, rhodopsin-like InterPro Predicted Protein Domain Annotations 1.0 null BRD-K31021810 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27431 BRD-K41185648 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07825 CRCGN017_MCF10A.WT.HP_24H:C20 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.1488 BRD-K09146396 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.71853 butylated-hydroxytoluene LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23861 MCC13 COSMIC Cell Line Gene Mutation Profiles 1.0 null SU-DHL-8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.30581 BRD-K49029187 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.28459 BRD-K23553911 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.80641 Olfactory receptor neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.352 single-multicellular organism process GO Biological Process Annotations 2015 1.0 null Hyperglycemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.351 BRD-K19168437 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.39377 animal TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052952 Brain Lower Grade Glioma_LGG_TCGA-FG-5965-01B-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56192 mRNA_EED_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Olfactory gland TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.338 BRD-K08409548 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07194 dorsolateral prefrontal cortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09584 Cortical endoplasmic reticulum COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.701 BRD-K50367303 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.36295 oculomotor nucleus, Edinger-Westphal subnucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45667 BRD-K39543844 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3264 KMS-28BM Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.07658 G protein-coupled receptor activity GO Molecular Function Annotations 2023 1.0 null BRD-K44193634 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02113 Lymphoma_burkitts(Raji) BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.30003 MEL-HO Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.01865 Flag leaf TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.524 CRCGN017_MCF10A.TP53.M_24H:N16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.63375 HS766T CCLE Cell Line Gene Expression Profiles 1.0 1.42119 HS 852.T Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.21611 BRD-K59507746 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11311 KYSE-150 COSMIC Cell Line Gene Mutation Profiles 1.0 null CRCGN016_MCF10A.TP53.M_24H:A16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.73955 BRD-K56520977 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03013 CRCGN015_MCF10A.TP53.M_24H:E17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.4016 Foxl2 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.9908 BRD-K90808566 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32246 Protoxylem TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.138 superior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.10819 CRCGN008_HEPG2_24H:I03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.1062 NCI-H1703 GDSC Cell Line Gene Expression Profiles -1.0 -1.58197 BRD-K09250647 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.64319 MXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.0464 DUXA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.227 Dopaminergic neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.414 Olfactory bulb TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.843 Brain Lower Grade Glioma_LGG_TCGA-HT-7875-01A-11R-2403-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Genetic disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.511 Serotonergic neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.114 SNU601 DepMap CRISPR Gene Dependency 1.0 5.55323 BRD-K25876174 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10004 CRCGN015_MCF10A_48H:J16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.8622 Attention deficit hyperactivity disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.571 KYSE-450 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00734 NR1I3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.5788 CRCGN015_MCF10A_48H:F02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.3872 Ventral posterolateral nucleus of the thalamus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.94273 WholeBlood BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.16731 CRCGN017_MCF10A.TP53.M_24H:O21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.80495 magnocellular (medial) subparafascicular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52414 BRD-K36197756 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.06121 Hypoglycemia DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.607 RSV_4Hour_19459069_GSE3397 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -2.26538 inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.0476 MFM-223 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.881634 BRD-K68084083 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15489 cell surface receptor signaling pathway GO Biological Process Annotations 2015 1.0 null BRD-K96389533 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.45936 CRCGN009_HEPG2_24H:K02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.90763 FOXL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.9625 Basal node TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.733 BRD-K56595246 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.0438 CRCGN011_HEPG2_24H:G15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.417 Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5187-01A-01R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null betamethasone-dipropionate LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.75842 Brain Lower Grade Glioma_LGG_TCGA-FG-6688-01A-11R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN017_MCF10A.TP53.M_24H:L22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.2952 Root primordium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.612 Dsl1/NZR complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.587 HOXD12::ELK1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.5066 496100538_HIP_no dementia_no TBI_87_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.24324 H3K4me3_retinal pigment epithelial cell_hg19_1 ENCODE Histone Modification Site Profiles 1.0 null KU812 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.19388 BRD-K35852282 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13271 LB1047RCC DepMap CRISPR Gene Dependency 1.0 3.19483 LU-134-A GDSC Cell Line Gene Expression Profiles -1.0 -1.64879 H3K27me3_CD14-positive monocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K92239253 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.477 Diabetes mellitus DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.42 Labellum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.772 BRD-K03035008 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.6077 BRD-K78310215 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16185 BRD-K24864035 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.45538 BRD-K66907139 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.01032 FOXP2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5822 posteroventral (inferior) parietal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.85547 BRD-K10705624 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.81798 G protein-coupled receptor activity GO Molecular Function Annotations 2025 1.0 null amygdalohippocampal transition zone, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.14911 Lung adenocarcinoma_LUAD_TCGA-MP-A4TA-01A-21R-A24X-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null POU4F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.7795 SG in posterior frontal cortex (motor cortex) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.50172 Neuropil TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.109 BRD-K75038114 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.144 BRD-K71345532 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.6703 RCC-FG2 COSMIC Cell Line Gene Mutation Profiles 1.0 null SKN-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K76492619 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.55439 Sox17 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.0411 Respiratory epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.963 FOXI1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0586 layer 2 of LOT Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51488 CRCGN016_MCF10A.TP53.M_24H:K05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 8.2525 LAMA84 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.07355 NCI-H358 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.890354 PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1 Rummagene Transcription Factor Associations 2026 1.0 null inner CP in temporal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.102 oculomotor nuclear complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.02267 MEOX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5868 NCI-H1648 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.13669 PMC8192774__F3 PFOCR Pathway Figure Associations 2024 1.0 null F36P CCLE Cell Line Gene CNV Profiles 1.0 1.85278 FOSB::JUN JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.6272 post-traumatic stress disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.041 YMB-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852025 ETS1-21867929-TH2-MOUSE ChEA Transcription Factor Targets 2022 1.0 null induseum griseum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48479 Paraventricular hypothalamic nucleus, magnocellular division Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.29299 substance-related disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.074 DIABLO CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2478 BRD-K92374432 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.31264 CRCGN016_MCF10A.WT.HP_24H:A17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.21199 IZ in midlateral extrastriate cortex (area 19) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.33435 CRCGN017_MCF10A.WT.HP_24H:P03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.2236 oculomotor nucleus, main part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05653 integral component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.140749 AN3 CA Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.14357 mantle zone of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.0444 cell periphery COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 HECW2 Pathway Commons Protein-Protein Interactions 1.0 null NKX6-3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.9494 PMC9378714-41467_2022_31999_MOESM10_ESM.xlsx-Supplementary_Data_7-Supplementary_Data_7_Collation_of_genes_possible_regulated_or_co-expressed_with_ELF5_ELF5 Rummagene Transcription Factor Associations 2026 1.0 null FAM83D CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.55918 BRD-K57782577 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.75086 Dopaminergic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.247 Sporangiospore TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.528 HPAFII DepMap CRISPR Gene Dependency 1.0 5.0745 positive regulation of catalytic activity GO Biological Process Annotations 2015 1.0 null BRD-K82521348 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05132 integral component of membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 CRCGN017_MCF10A.TP53.M_24H:G14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.85912 BRD-K32146668 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11681 BRD-K41133627 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02099 Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K20624967 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27026 BRD-K95591629 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29928 NOB1 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.9819 layer V of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.82285 Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-4882-01A-02R-1426-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TBX21 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.7683 cell part GO Cellular Component Annotations 2015 1.0 null BRD-K18296568 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07877 posterior (caudal) superior temporal cortex (area 22c)_19 pcw_F_12885 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.12451 intermediate stratum of r10BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.06867 Brain Lower Grade Glioma_LGG_TCGA-QH-A86X-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_TCEA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null periventricular stratum of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03991 COR-L47 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.24425 Disease Reactome Pathways 2014 1.0 null r8 part of the paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31184 PRKAB2 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.53014 unique GeneRIF Biological Term Annotations 1.0 null ZNF675 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 46.8504 BRD-K09720842 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46216 BRD-K27692586 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.70685 primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.61841 intrinsic component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.12939 BRD-K37592272 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.02995 CRCGN015_MCF10A.WT.HP_24H:B10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.71991 Paraventricular hypothalamic nucleus, parvicellular division, medial parvicellular part, dorsal zone Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.53515 intrinsic component of membrane GO Cellular Component Annotations 2015 1.0 null CRCGN009_HEPG2_24H:N04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.61066 NKX6-1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.348 biological regulation GO Biological Process Annotations 2015 1.0 null Class A/1 (Rhodopsin-like receptors) Reactome Pathways 2014 1.0 null A4 noradrenergic cell group Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04517 Bed nucleus of the accessory olfactory tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.01801 Brain Lower Grade Glioma_LGG_TCGA-E1-5307-01A-01R-1896-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null lateral habenular nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.01731 Psychotic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 2.034 TrigeminalGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.948312 CRCGN015_MCF10A_48H:M22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.06374 496100380_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.85749 BRD-K82019575 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.42808 TBX19 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6395 Brain Lower Grade Glioma_LGG_TCGA-KT-A7W1-01A-11R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null potently GeneRIF Biological Term Annotations 1.0 null MCF12A Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.673688 IV, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.45296 layer 1 of AOD cortex Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05167 CRCGN017_MCF10A.WT.HP_24H:O18 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.4909 BRD-K29713418 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.69449 plexiform layer of TuStr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04607 SU-DHL-5 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.37749 Mesocotyl TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.556 BRD-K69826976 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.59339 Nucleus of Darkschewitsch Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.63039 PAX5_OE_GDS4978_547_human_L428 GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null BRD-K62072978 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.67085 inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.960235 cuneate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.843398 liminal part of the r10 alar plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08114 positive regulation of lyase activity GO Biological Process Annotations 2015 1.0 null intermediate part of r8B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.00229 496100434_HIP_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.63238 H2AFZ_keratinocyte_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null PCM6 CCLE Cell Line Gene Expression Profiles 1.0 1.41115 primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -2.31571 anteroventral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.24515 posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.3969 451LU COSMIC Cell Line Gene Mutation Profiles 1.0 null Sox1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 26.7297 periventricular stratum of PPaA Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16226 BTS LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.70844 SU.86.86 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1571 lateral terminal nucleus of the accessory optic tract, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17883 Neurodegenerative disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.212 intermediate part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.13569 BRD-K87875370 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21032 fulvestrant-367 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Type II polyketide synthase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.671 intermediate stratum of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38068 biogenic GeneRIF Biological Term Annotations 1.0 null BRD-K19817946 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.27826 G alpha (s) signalling events Reactome Pathways 2024 1.0 null CRCGN012_HEPG2_24H:K01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.70107 BRD-K25149224 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.44573 GATA3_T47D_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null CORL23 CCLE Cell Line Gene CNV Profiles -1.0 -2.77394 Root vascular cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.075 BRD-K59324446 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.59249 M059K CCLE Cell Line Gene CNV Profiles 1.0 1.5654 JEKO-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.965522 BRD-K90527476 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18735 BRD-K24529791 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.45972 Rectum adenocarcinoma_READ_TCGA-AH-6549-01A-11R-1830-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Mesocorticolimbic dopaminergic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.7 Ventral posteromedial nucleus of the thalamus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.85735 SUIT2 DepMap CRISPR Gene Dependency 1.0 4.76551 BRD-A87325732 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.28436 Tassel TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.713 r6 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.3238 Dendritic knob COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.628 Acute Myeloid Leukemia_LAML_TCGA-AB-2933-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K40251180 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04545 external part of AOD Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.03991 taar2 GeneRIF Biological Term Annotations 1.0 null BRD-K78009480 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24757 BRD-K74289419 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2301 TEAD4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.6449 MKN-45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03746 intrinsic component of plasma membrane GO Cellular Component Annotations 2015 1.0 null CRCGN017_MCF10A.WT.HP_24H:K22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.68 FOS::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.1256 LASV_FML29_8hr_24069471_GSE41300 GEO Signatures of Differentially Expressed Genes for Viral Infections -1.0 -1.98089 EBNA1-20929547-CHIP-SEQ-RAJI-CELLS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Anterior olfactory nucleus, external part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.38642 HOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.526 KMS27 CCLE Cell Line Gene CNV Profiles -1.0 -1.88848 system process GO Biological Process Annotations 2015 1.0 null BRD-K37625653 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34844 superficial stratum of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48479 dorsolateral prefrontal cortex_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.51193 Dmrt1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.676 OSC19 DepMap CRISPR Gene Dependency 1.0 5.90606 superficial stratum of m1AL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.16761 ZIM3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 45.3512 Endocrine system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.07 BRD-K75626008 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.23682 Pollen tube TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.671 NCI-H2126 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.927838 lateral ganglionic eminence_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.837394 periventricular stratum of PalSe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.10905 SNU61 CCLE Cell Line Gene CNV Profiles 1.0 1.54972 Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K41829399 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.23578 496100529_HIP_no dementia_no TBI_89_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.51735 VZ in caudal subicular cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.61095 neurological system process GO Biological Process Annotations 2015 1.0 null Esophagus - Gastroesophageal Junction GTEx Tissue Gene Expression Profiles 2023 1.0 7.21239 CRCGN015_MCF10A_48H:G13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.94735 EFM-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.77738 BRD-K22599787 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3981 posterior (caudal) superior temporal cortex (area 22c)_25 pcw_F_12948 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.00323 Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null FOXA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.6914 BRD-K87781745 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.97892 ZNF75A CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.87774 each GeneRIF Biological Term Annotations 1.0 null superficial stratum of Str Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06146 BRD-K59159023 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00726 496100497_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.24513 496100495_FWM_no dementia_TBI_90-94_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 3.95966 medial part of r9B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09363 CRCGN017_MCF10A.WT.HP_24H:P19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.5439 dorsal raphe nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.29989 BRD-K13086002 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.46683 BRD-K65725294 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26549 Disease of metabolism DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.569 BRD-A02501536 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.83879 ronidazole-6134 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null Copula pyramidis, granular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09965 ACHN BioGPS Cell Line Gene Expression Profiles -1.0 -0.9875 POLR2A_MCF 10A_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K40210962 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.53722 STAT1-17558387-HELA-HUMAN ChEA Transcription Factor Targets 2022 1.0 null COV362 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.927838 Frontoparietal cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.77 CRCGN015_HEPG2_48H:J22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.92445 BRD-K33221810 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.85612 g-protein coupled amine receptor activity GO Molecular Function Annotations 2015 1.0 null CDX2-19796622-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null paraventricular nucleus of the hypothalamus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.69917 Genital pore TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.533 CRCGN012_HEPG2_24H:N04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.7064 BRD-K77150932 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15425 ZNF217_OE_GDS4885_317_human_MDA-MB-231 breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null CEBPA JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.5914 Foxo3 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 17.1513 ZNF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 42.7219 MKN-74 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35335 PRECLH CCLE Cell Line Gene Expression Profiles -1.0 -1.94951 BRD-K12097074 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.07758 CD14+_Monocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.71259 NCI-H2595 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.939362 BRD-K00377328 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.95793 CRCGN017_MCF10A.WT.HP_24H:G01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.39969 regulation of biological process GO Biological Process Annotations 2015 1.0 null BRD-K70751829 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.16495 Orbital area, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.87926 BRD-K27616003 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14241 chemosensory GeneRIF Biological Term Annotations 1.0 null CRCGN010_HEPG2_24H:D05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.49973 CRCGN012_HEPG2_24H:C22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.23353 MFE296 DepMap CRISPR Gene Dependency 1.0 4.51487 BRD-K34620971 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02967 CA4 field, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.30794 SNU1196 DepMap CRISPR Gene Dependency 1.0 2.65595 CRCGN016_MCF10A.WT.HP_24H:C19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.8066 SNU423 CCLE Cell Line Gene CNV Profiles 1.0 1.42332 regulation of lyase activity GO Biological Process Annotations 2015 1.0 null SuperiorCervicalGanglion BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.976714 BRD-A68175400 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.50032 Interstitial nucleus of Cajal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.32172 reported GeneRIF Biological Term Annotations 1.0 null inner SZ in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.963161 LS411N Achilles Cell Line Gene Essentiality Profiles -1.0 -1.23232 BRD-K12826618 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.4942 CRCGN014_HEPG2_24H:P03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.69741 PMC9508118-42003_2022_3857_MOESM6_ESM.xlsx-e-Classification_of_camel_SON_basal_genes_-_G_protein_coupled_receptors_SON Rummagene Transcription Factor Associations 2026 1.0 null MEIS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.7917 184A1N4 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.04665 Secretory trichome TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.284 sensory perception of chemical stimulus GO Biological Process Annotations 2015 1.0 null BRD-K73145196 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11439 H3K27me3_fibroblast of lung_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K45712538 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.5604 IM95 DepMap CRISPR Gene Dependency 1.0 11.4311 hippocampus (hippocampal formation)_2 yrs_F_12979 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.954504 TCF7L2_HEK293_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null Nucleus of the lateral olfactory tract, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.69961 CRCGN015_HEPG2_48H:M16 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.35751 Anxiety disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.341 BRD-K45695360 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03625 HCC202 CCLE Cell Line Gene CNV Profiles -1.0 -2.68184 Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RR-01A-21R-A34F-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Developmental disorder of mental health DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.418 BEN cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.221 G59 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.965522 Brain disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.288 Peripheral nervous system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.891 GATA2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.4957 BRD-K89832379 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19577 Vomeronasal organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.125 OCI-LY-19 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.51702 primary somatosensory cortex (area S1, areas 3,1,2)_24 pcw_M_12288 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.08158 medial mammillary nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.34085 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4691-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 3.11412 Infralimbic area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05372 Bed nuclei of the stria terminalis, anterior division, ventral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30082 SG in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.24642 basomedial nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.17387 r9 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44933 TCF7L2 ENCODE Transcription Factor Targets 1.0 null Amylin receptor complex 1 COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.55 BRD-K31621670 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06755 FOXK2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1613 496100608_FWM_no dementia_no TBI_78_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.83841 Anterior olfactory nucleus, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.45987 RERF-LC-MS GDSC Cell Line Gene Expression Profiles -1.0 -1.43298 trace-amine receptor activity GO Molecular Function Annotations 2025 1.0 null positive regulation of biological process GO Biological Process Annotations 2015 1.0 null GPCR, rhodopsin-like, 7TM InterPro Predicted Protein Domain Annotations 1.0 null Lek TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.753 POLR2A ENCODE Transcription Factor Targets 1.0 null BRD-K69515345 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.63396 suboptic nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11324 superficial stratum of PcPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.50678 Esrrg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 21.0988 OCI-LY-10 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.64603 Mushroom body TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.859 Root hair COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.025 paper GeneRIF Biological Term Annotations 1.0 null GPCR downstream signalling Reactome Pathways 2024 1.0 null L-363 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.56623 facial motor nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.55913 BRD-K72892670 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.18273 BRD-K71671197 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.73444 Adventitious root primordium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.839 regulation of phosphorus metabolic process GO Biological Process Annotations 2015 1.0 null BRD-K78603273 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.39411 HUH-7 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.852638 Nasal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.374 SNU886 CCLE Cell Line Gene Expression Profiles -1.0 -2.28617 ChIP_NR0B1_18358816 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Bed nuclei of the stria terminalis, posterior division, strial extension Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.23515 CRCGN017_MCF10A.WT.HP_24H:N10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.067 BRD-K74382273 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00438 Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3427-01A-01R-0864-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K22718400 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.98258 Alzheimer's disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.02 BRD-K91944762 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04997 CRCGN017_MCF10A.TP53.M_24H:K23 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.8368 set GeneRIF Biological Term Annotations 1.0 null BRD-K03093950 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.35987 integral component of membrane GO Cellular Component Annotations 2015 1.0 null BRD-K48592348 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.14987 outer CP in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.84881 Cardiovascular system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.106 NCI-H2795 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33311 intermediate stratum of r8BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06066 r7 part of parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.29434 H3K4me1_ES-E14_mm9_2 ENCODE Histone Modification Site Profiles 1.0 null CADOES1 Achilles Cell Line Gene Essentiality Profiles 1.0 1.282 layer II of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.902618 Dendrite terminus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.406 Left nucleus COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.591 POU1F1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.7078 NFIC JASPAR Predicted Transcription Factor Targets 1.0 null mantle zone of r7BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.51059 BRD-K33177501 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10261 rostral subdivision of medial nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.63309 r10 part of basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.51437 4-aminobutyrate transaminase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.576 BRD-K78306305 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.54352 496100543_FWM_probable Alzheimer's disease_TBI_78_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.18167 MDAMB453 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.666036 THP-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.53787 NANOG-18692474-MESC-mouse ChEA Transcription Factor Binding Site Profiles 1.0 null FOS::JUNB JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6304 HOXA3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.5918 GM2493 BioGPS Cell Line Gene Expression Profiles 1.0 1.54864 OAW42 CCLE Cell Line Gene Expression Profiles 1.0 1.45852 NANOG-18347094-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null mantle zone of r9BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.12374 SRF JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.7056 Head and Neck squamous cell carcinoma_HNSC_TCGA-IQ-A6SH-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null endopiriform nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.01172 PC-3_[JPC-3] COSMIC Cell Line Gene Mutation Profiles 1.0 null Psoriasis vulgaris_Skin tissue_GSE14905 GEO Signatures of Differentially Expressed Genes for Diseases 1.0 2.50932 dorsal lateral geniculate nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.982752 Hairy cell leukemia cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.886 BRD-K35128023 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06491 ventricular (matrix) zone of pons Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.97475 DLD1 BioGPS Cell Line Gene Expression Profiles -1.0 -0.9875 regulation of camp metabolic process GO Biological Process Annotations 2015 1.0 null SCH DepMap CRISPR Gene Dependency 1.0 3.07688 Bed nuclei of the stria terminalis, posterior division, transverse nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.91223 PAX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.823 central nucleus of inferior colliculus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.55728 CRCGN016_MCF10A.TP53.M_24H:O15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.93431 Central linear nucleus raphe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31943 Endoplasmic reticulum tubular network COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.687 Inherited metabolic disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.509 BRD-K69468381 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.55872 BRD-A73965025 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.3311 GSX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.833 membrane COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 IRF3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 87.7872 liminal reticular formation of m2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11475 BRD-K68594161 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.14295 r9 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.58688 BRD-K53224568 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.23436 WM2664 CCLE Cell Line Gene Expression Profiles -1.0 -1.89276 CRCGN017_MCF10A.WT.HP_24H:N09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.54315 NCI-H2810 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.940468 BRD-K06029218 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.09906 BRD-K33770771 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.55439 genistein-382 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null BRD-K07667635 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18541 Mad-Max complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.967 BRD-K83684822 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.01223 layer IIIa of caudal entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.09539 BRD-K71204648 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.47557 BMPR1A_knockout_222_GSE48092 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -0.742243 motor nucleus of trigeminal nerve, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 2.13037 guanfacine-5621 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K85513726 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.72983 CRCGN015_MCF10A.TP53.M_24H:J07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.3888 MDST8 COSMIC Cell Line Gene Mutation Profiles 1.0 null Nasal cavity TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.885 at3.1 TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.805 superficial stratum of JcPL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.39216 Inflorescence stalk TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.903 cognitive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.36741 CRCGN015_MCF10A_48H:J23 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.56671 BRD-K62698674 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.63672 SKNO1 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.31713 CRCGN017_MCF10A.WT.HP_24H:M07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.5877 NEUROD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.8961 BRD-K20009653 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.41467 IRF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 26.2743 BRD-K21786986 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30244 HCC1428 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.927838 integral component of plasma membrane GO Cellular Component Annotations 2015 1.0 null r7 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22221 CRCGN015_MCF10A.TP53.M_24H:L09 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.08895 BRD-K70315531 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35749 mRNA_SMAD1_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null IRF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 56.1017 BRD-K04918285 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13051 Medullary reticular nucleus, ventral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.04708 regulation of cyclic nucleotide biosynthetic process GO Biological Process Annotations 2015 1.0 null BRD-K65959331 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.85824 CP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.31497 HT29 BioGPS Cell Line Gene Expression Profiles 1.0 2.04471 SKBR3 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.785035 Dendritic tuft COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.93 CRCGN016_MCF10A.TP53.M_24H:L10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.74299 rostral interstitial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.56578 regulation of purine nucleotide metabolic process GO Biological Process Annotations 2015 1.0 null BRD-K41135617 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25951 BRD-K85418917 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.45868 CRCGN015_HEPG2_48H:B10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.2028 Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GS-A9TV-01A-11R-A38C-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K09388706 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.32104 BRD-K04650027 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.743 amygdaloid complex_36 yrs_M_12302 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.11436 SNU119 CCLE Cell Line Gene CNV Profiles 1.0 2.32165 regulation of nucleotide biosynthetic process GO Biological Process Annotations 2015 1.0 null ARTN CM4AI KOLF21J CRISPRi Gene Perturbation Atlas -1.0 -2.01491 HDAC6_K562_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K60780031 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15754 Central nervous system disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.414 regulation of catalytic activity GO Biological Process Annotations 2015 1.0 null LNCaP clone FGC TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.504 BRD-K37283718 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.0569 CRCGN015_MCF10A.TP53.M_24H:O12 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.21675 BRD-K25045770 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.39005 BRD-K63987422 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.2422 BRD-K05127596 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24275 External plexiform layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.841 Gastric juice TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.557 TRPS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.6946 plasma membrane LOCATE Predicted Protein Localization Annotations 1.0 null mantle zone of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.09363 CRCGN013_HEPG2_24H:N04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.99815 RCOR1 ChEA Transcription Factor Targets 1.0 null posterior tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0144 cortico-medial group, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.06241 outer CP in caudal cingulate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.0171 striatum_13 pcw_F_12834 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.29336 intermediate stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31787 IL21_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null Axillary bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.634 whole body TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052953 BRD-K76449854 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.42601 CRCGN016_MCF10A.TP53.M_24H:F11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.2427 BRD-K20051655 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04548 HOXD9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.1469 BRD-K77697725 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25784 CRCGN016_MCF10A.TP53.M_24H:P12 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.61076 Edinger-Westphal nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.80842 ATF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.4062 RAMOS Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.42104 BRD-K94194278 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.478 LN443 CCLE Cell Line Gene Expression Profiles -1.0 -1.86374 PL45 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.890354 EMX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.0795 SUDHL4 CCLE Cell Line Gene Expression Profiles 1.0 1.57394 FOXA1 ENCODE Transcription Factor Targets 1.0 null mRNA_TCF7L2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CRCGN015_MCF10A_48H:G05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.2758 superficial stratum of r9BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.44752 Brain Lower Grade Glioma_LGG_TCGA-S9-A6TV-01A-12R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN015_MCF10A.TP53.M_24H:O07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.4168 CRCGN015_MCF10A_48H:P05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.7508 ChIP_NANOG_18692474 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null BRD-K30699866 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 5.35047 Fundus of striatum Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.94098 anterior orbital gyrus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.27341 lateral part of r10B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.66426 Malpighian tubule TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.107 Brain Lower Grade Glioma_LGG_TCGA-HW-7486-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Brain Lower Grade Glioma_LGG_TCGA-HT-7471-01A-11R-2256-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN015_MCF10A_48H:O11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 8.8745 EVSA-T COSMIC Cell Line Gene Mutation Profiles 1.0 null orbital frontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.12739 outer CP in dorsomedial extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.942277 CRCGN014_HEPG2_24H:D01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.24433 superficial stratum of r1BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06901 Anterior olfactory nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.013 MEWO COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K34624391 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06495 H3K27me3_endothelial cell of umbilical vein_hg19_3 ENCODE Transcription Factor Binding Site Profiles 1.0 null CRCGN016_MCF10A.WT.HP_24H:D05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.17245 intermediate stratum of SeDg Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.04607 seem GeneRIF Biological Term Annotations 1.0 null bronchoalveolar system TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.479312 BRD-K90284572 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.57024 BRD-K28467592 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.34785 KMS28BM CCLE Cell Line Gene CNV Profiles -1.0 -1.40689 BRD-K33204113 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.69659 POU3F2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 28.0388 RS11846 BioGPS Cell Line Gene Expression Profiles 1.0 1.00694 Taproot TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.86 Prostate BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.71259 periventricular stratum of r1Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.40903 Neurosecretory cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.58 posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.29844 THP1 CCLE Cell Line Gene CNV Profiles 1.0 1.51605 r9 portion of ambiguous motor nucleus (postmigratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72264 SUM1315MO2 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -0.652481 BRD-K77869482 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.58268 r9 part of paragigantocellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.166 RI-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.56623 BRD-K42663584 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25097 IGR-1 COSMIC Cell Line Gene Mutation Profiles 1.0 null CardiacMyocytes BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.55362 MM160113 DepMap CRISPR Gene Dependency 1.0 3.19199 ZNF784 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.2332 caudal zona incerta Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.42025 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A73P-01A-11R-A32P-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null NCIH1385 CCLE Cell Line Gene CNV Profiles -1.0 -2.10712 EVX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.0413 debrisoquin LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.69933 GSX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0213 Parastrial nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.73587 Olfactory lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.865 Chloride channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.054 TEF-1 MotifMap Predicted Transcription Factor Targets 1.0 null CRCGN008_HEPG2_24H:G24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.94615 ATM_knockout_74_GSE23116 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations -1.0 -1.48116 Neuro D MotifMap Predicted Transcription Factor Targets 1.0 null 496100490_HIP_no dementia_no TBI_86_F Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.3216 Diagonal band TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.69 BRD-K10481024 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.69654 BRD-A63704386 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.14462 BRD-K60430317 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.38041 mantle zone of r10Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.08114 Disease of cellular proliferation DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.011 CRCGN015_MCF10A.TP53.M_24H:P19 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.2858 KMS28BM CCLE Cell Line Gene Expression Profiles 1.0 1.3943 mantle zone of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.46948 disease DISEASES Text-mining Gene-Disease Association Evidence Scores 1.0 0.039599 primary auditory cortex (core)_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.05817 VZ in postamygdaloid region Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.24708 CDX2 ChEA Transcription Factor Targets 1.0 null ZNF354A JASPAR Predicted Human Transcription Factor Targets 2025 1.0 69.7316 BRD-K99387963 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04283 GATA1::TAL1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.9802 CRCGN017_MCF10A.WT.HP_24H:O12 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.43585 regulation of cellular biosynthetic process GO Biological Process Annotations 2015 1.0 null BRD-K00191683 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13526 primary motor cortex (area M1, area 4)_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.17616 anteromedial nucleus of thalamus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.00978 membrane part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.043275 BRD-K14087001 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.83343 BRD-K04731905 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.20559 GATA3 ENCODE Transcription Factor Targets 1.0 null CRCGN017_MCF10A.TP53.M_24H:K24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.27219 Orbital area, medial part, layer 2 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.24939 BRD-K70343553 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.77507 Acute Myeloid Leukemia_LAML_TCGA-AB-2917-03A-01T-0734-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null VMRC-LCD Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.07312 A673 Achilles Cell Line Gene Essentiality Profiles 1.0 1.14014 BRD-K65729622 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.13739 IL15_UP.V1 MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations -1.0 null Depressive disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.674 CRCGN015_MCF10A_48H:K10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.59639 BRD-K62983405 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.58905 SH4 CCLE Cell Line Gene CNV Profiles -1.0 -1.69406 MYC ENCODE Transcription Factor Targets 1.0 null positive regulation of cellular metabolic process GO Biological Process Annotations 2015 1.0 null ST486 CCLE Cell Line Gene Expression Profiles 1.0 1.76212 SCC-15 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 2.83194 G protein-coupled amine receptor activity GO Molecular Function Annotations 2025 1.0 null Idiopathic generalized epilepsy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.012 SUDHL8 CCLE Cell Line Gene CNV Profiles 1.0 2.05523 BRD-K35469110 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21415 intermediate stratum of p2ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.38792 CRCGN015_MCF10A.WT.HP_24H:C07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.21613 BRD-K98535230 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.21312 CRCGN014_HEPG2_24H:K02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 8.32292 spanning component of plasma membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.291787 Infralimbic area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.11773 parasubicular cortex (parasubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.39625 Kidney Chromophobe_KICH_TCGA-KN-8429-11A-01R-2315-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null superficial stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.16664 shell of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.96555 taar1 GeneRIF Biological Term Annotations 1.0 null BRD-K62833556 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26277 respiratory mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.869794 Periglomerular cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.226 BRD-K12986423 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.45894 olfactory epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 1.01812 BRD-K77578964 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.40571 paracentral lobule, posterior part, right, lateral bank of gyrus Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -2.36874 PL-21 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.05298 Leydig cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.011 HOS GDSC Cell Line Gene Expression Profiles 1.0 1.88919 ZR-75-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852611 Brain Lower Grade Glioma_LGG_TCGA-HT-7472-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K59744424 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06704 intermediate stratum of r7BL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.22221 mediodorsal nucleus of thalamus_21 yrs_F_13057 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.07574 rostral subdivision of paraventricular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.49189 r10 part of ventral parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37984 regulation of metabolic process GO Biological Process Annotations 2015 1.0 null POU3F2-20337985-501MEL-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RS-01A-12R-A33Z-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K78615842 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.1352 MKN45 COSMIC Cell Line Gene Mutation Profiles 1.0 null YY1 JASPAR Predicted Transcription Factor Targets 1.0 null BRD-K21036759 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.50275 Orbital area, lateral part, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.97625 cell part LOCATE Predicted Protein Localization Annotations 1.0 null CRCGN008_HEPG2_24H:L04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.1008 BRD-K70276322 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.21924 VIIB, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.10268 Nucleus of the brachium of the inferior colliculus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.47687 outer SZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.932308 BRD-K61924304 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00414 rostral group of intralaminar nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.92994 PIAS1_Depletion_GDS5076_12_human_MDA-MB 231 breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations -1.0 null Liver hepatocellular carcinoma_LIHC_TCGA-RC-A6M3-01A-11R-A32O-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TEAD3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 34.3341 CRCGN017_MCF10A.WT.HP_24H:N18 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.1396 CCLFUPGI0005T DepMap CRISPR Gene Dependency 1.0 3.07744 Liver hepatocellular carcinoma_LIHC_TCGA-UB-A7ME-01A-11R-A33J-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K60907484 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.44995 PDX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.8955 BRD-K63154470 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.22401 paraventricular nucleus, cap part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.87926 OV90 CCLE Cell Line Gene Expression Profiles 1.0 1.4138 BRD-K13350372 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.42141 BRD-K06355852 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.82229 LIVF001-027 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00911 Olfactory tract TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.102 BRD-K57182060 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.11421 Primary visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.61761 RPMI8402 CCLE Cell Line Gene Expression Profiles 1.0 1.63339 Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A952-01A-11R-A38B-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K96218803 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.34295 MZ in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.939583 BRD-K34314104 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.12426 CRCGN014_HEPG2_3H:N04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.5105 membrane LOCATE Predicted Protein Localization Annotations 1.0 null Trace amine associated receptor family InterPro Predicted Protein Domain Annotations 1.0 null Duodenal mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.825 Parapyramidal nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38871 BRD-K02087489 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00487 positive regulation of molecular function GO Biological Process Annotations 2015 1.0 null CRCGN015_HEPG2_48H:O01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.91161 Paraflocculus, molecular layer Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.17734 cellular_component GO Cellular Component Annotations 2015 1.0 null BRD-K71452779 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15576 WIL2-NS cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.552 BRD-K34858602 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.35356 PADI4 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.40118 RAD21-21589869-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null anterior nucleus of pulvinar Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.07304 Olfactory organ TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.011 r7 part of the basointermediate reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.54403 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5561-01A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null globose nucleus, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.04228 outer plexiform zone in extrastriate cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1284 regulation of nucleotide metabolic process GO Biological Process Annotations 2015 1.0 null BRD-K98586629 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.8519 CRCGN014_HEPG2_24H:H24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.4848 UACC-257 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.881634 medial geniculate complex, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.13496 Adventitious root TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.872 mantle zone of the IG Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.48312 klf4_17017123_rko_gof_human_gpl96_gds1942 GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations 1.0 0.027664 FOXC1 JASPAR Predicted Transcription Factor Targets 1.0 null ZNF724 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.88536 positive regulation of camp biosynthetic process GO Biological Process Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6087-11A-01R-1672-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null CRCGN011_HEPG2_24H:N02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.28815 IRF8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.2983 SP in caudal perirhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.872488 TC71 CCLE Cell Line Gene Expression Profiles 1.0 1.72347 KURAMOCHI Achilles Cell Line Gene Essentiality Profiles -1.0 -1.73004 BRD-K72565671 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.12735 intermediate stratum of r1BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.30768 CRCGN015_MCF10A.WT.HP_24H:K18 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.76548 CRCGN010_HEPG2_24H:K02 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.75603 T84 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.95209 GATA6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 29.0578 CRCGN013_HEPG2_24H:C22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.29488 TE5 CCLE Cell Line Gene Expression Profiles 1.0 1.87936 BRD-K79730625 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.48431 CRCGN015_MCF10A_48H:G15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.4893 HOXB7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.8735 SNU324 CCLE Cell Line Gene CNV Profiles -1.0 -1.39795 orbital frontal cortex_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -0.908432 BRD-K37269981 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.84034 Ovarian fluid TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.593 IV, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.2218 vestibular nuclei, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.22952 BRD-K61271364 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2832 ZNF558 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 82.3985 BRD-K60905390 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.10963 HDAC6 ENCODE Transcription Factor Targets 1.0 null primary auditory cortex (core)_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.835475 BRD-K26237438 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.72813 brain TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.222938 Rarb JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 67.963 CRCGN014_HEPG2_24H:I24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.33193 CRCGN016_MCF10A.WT.HP_24H:D04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.3455 BRD-K01978082 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.88729 Superior central nucleus raphe, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05234 BC-3 GDSC Cell Line Gene Expression Profiles 1.0 2.10063 BRD-A98714080 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24612 BRD-K00562490 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.40151 Vascular disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.105 r10 part of basomedial reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.27412 HOXA6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.6178 Crus I, left, paravermis Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.830294 BRD-K29519734 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26906 blood GeneRIF Biological Term Annotations 1.0 null BRD-K96817767 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.50205 MDA-MB-415 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1571 CRCGN011_HEPG2_24H:H15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.7145 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YU-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null GPCR ligand binding Reactome Pathways 2014 1.0 null IRF9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.6862 TEAD1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 44.5171 HSG BioGPS Cell Line Gene Expression Profiles -1.0 -0.9875 ZNF547 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.762 Sertoli cell line TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.922 positive regulation of phosphate metabolic process GO Biological Process Annotations 2015 1.0 null BRD-K12959846 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.00812 biological_process GO Biological Process Annotations 2015 1.0 null BRD-K26272845 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43434 NCIH146 CCLE Cell Line Gene CNV Profiles 1.0 1.75663 Stria terminalis TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.884 intermediate stratum of r9BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.42316 Pancreatic somatostatinoma DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.592 transmembrane signaling receptor activity GO Molecular Function Annotations 2015 1.0 null histamine-gated chloride channel complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.859 K562 BioGPS Cell Line Gene Expression Profiles 1.0 1.17125 JHOS-3 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K66973998 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.12173 hippocampus (hippocampal formation)_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.87411 PAX6 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4651 BRD-K37000177 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.36547 SEM Achilles Cell Line Gene Essentiality Profiles 1.0 1.10658 FOXA1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.0166 Posterolateral visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.15515 697 DepMap CRISPR Gene Dependency 1.0 2.10454 MAP3K1_knockout_245_GSE39240 GEO Signatures of Differentially Expressed Genes for Kinase Perturbations 1.0 1.26918 only GeneRIF Biological Term Annotations 1.0 null BRD-K22449045 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3712 Ppara JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 18.1287 Anterior olfactory nucleus, dorsal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.23104 Acute Myeloid Leukemia_LAML_TCGA-AB-2851-03A-01T-0736-13 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null respiratory epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.550901 Odorant GPCRs(Mus musculus) WikiPathways Pathways 2014 1.0 null BRD-K86268010 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.04004 BRD-K40001806 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.3009 BRD-K52225720 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.11343 RCC4 CCLE Cell Line Gene Expression Profiles -1.0 -2.21104 A-498 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852025 BRD-K59765110 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.08345 H2BC11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.17102 VAX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.2588 multicellular organismal process GO Biological Process Annotations 2015 1.0 null SU8686 DepMap CRISPR Gene Dependency 1.0 2.73374 CRCGN016_MCF10A.TP53.M_24H:A17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.27318 H2AFZ ENCODE Transcription Factor Targets 1.0 null lateral intermediate part of entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1489 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JV-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K26976202 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.96962 RCOR1-19997604-NEURONS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null HOXD8 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 15.3331 ERG_01_216 KnockTF Gene Expression Profiles with Transcription Factor Perturbations -1.0 -0.59921 SOX2-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null Glomerular layer TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.578 Rhabdomere COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.631 r9 part of gigantocellular reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.30024 CRCGN016_MCF10A.TP53.M_24H:E17 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.49126 SUP-T1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.951 NCIH1876 CCLE Cell Line Gene CNV Profiles 1.0 2.07962 G44 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.23711 BRD-K23296676 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.08917 Ethmoid bone TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.06 superficial stratum of r9Lim Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.72527 Tegmentum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.498 HCC1419 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.28649 BRD-K38131403 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30331 PAX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4505 G protein-coupled receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.955 MFE-319 COSMIC Cell Line Gene Mutation Profiles 1.0 null OVMANA CCLE Cell Line Gene Expression Profiles 1.0 1.62942 CCK81 CCLE Cell Line Gene CNV Profiles 1.0 2.16721 BRD-K93457574 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02655 FOXS1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.1123 ZNF766 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 38.2795 RAD21 ChEA Transcription Factor Targets 1.0 null temporal neocortex_9 pcw_M_12833 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.12264 BRD-K48744855 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26609 IZ in caudal midinferior temporal cortex (area TF) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.33955 Brain Lower Grade Glioma_LGG_TCGA-VW-A8FI-01A-11R-A36H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null regulation of adenylate cyclase activity involved in g-protein coupled receptor signaling pathway GO Biological Process Annotations 2015 1.0 null VZ in dorsomedial frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.91543 BRD-K11310449 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.15178 ventral posterior parvicellular nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.4936 Amine ligand-binding receptors Reactome Pathways 2024 1.0 null posterior hypothalamic area, right Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 0.847897 BRD-K02299361 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13367 posteroventral (inferior) parietal cortex_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.09584 496100436_FWM_no dementia_no TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.09083 BRD-K75610411 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24318 NCIH2286 CCLE Cell Line Gene Expression Profiles 1.0 1.37116 EM2 CCLE Cell Line Gene CNV Profiles 1.0 2.61628 FOSL1::JUND JASPAR Predicted Human Transcription Factor Targets 2025 1.0 20.1883 Rarg JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 81.6263 RISC-loading complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.68 GATA2 JASPAR Predicted Transcription Factor Targets 1.0 null detects GeneRIF Biological Term Annotations 1.0 null caudal division of IPC (area 39) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.3431 GATA3-21867929-TH1-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Bcl11b JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 19.1287 CRCGN015_HEPG2_48H:L04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.56364 ventral isthmic part of dorsal raphe nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.1657 Infralimbic area, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0073 U251 BioGPS Cell Line Gene Expression Profiles -1.0 -0.9875 FOXP4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.1398 Frontal lobe TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.792 CEBPD JASPAR Predicted Human Transcription Factor Targets 2025 1.0 23.5655 periventricular stratum of p1B Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.86708 STAT3 ENCODE Transcription Factor Targets 1.0 null spanning component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.291787 CAMA-1 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.03746 BRD-K64567083 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.30706 intermediate stratum of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.06005 CP in caudal hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.03849 BT-549 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.870386 BRD-K38211037 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.25038 H3K27me3_A549_hg19_2 ENCODE Transcription Factor Binding Site Profiles 1.0 null BRD-K25423143 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.24638 SNAPC5 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.80207 CRCGN017_MCF10A.WT.HP_24H:E10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.3032 dorsal part of m2A Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.00069 SPIC JASPAR Predicted Human Transcription Factor Targets 2025 1.0 37.5243 TCCSUP CCLE Cell Line Gene Expression Profiles -1.0 -3.41921 CWR22-Rv1 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.585 posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.823957 CRCGN014_HEPG2_24H:D11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.688 paraventricular nucleus, peduncular or principal part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.16311 mRNA_MEF2C_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Nose TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.37 BRD-K18620798 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.54168 Specific developmental disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.335 Hiv Infections DisGeNET Gene-Disease Associations 1.0 null CRCGN011_HEPG2_24H:N04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.2428 VZ in subgenual cingulate neocortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.878563 Dorsal nucleus raphe Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.09714 Olfactory epithelium TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 2.443 Cribriform plate TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.077 Celiac ganglion TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.697 mediodorsal nucleus of thalamus_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.09607 BRD-K63436783 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.83536 BRD-K01973494 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.95813 DOK DepMap CRISPR Gene Dependency 1.0 6.93019 BRD-K84936524 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.40586 MOLM-16 COSMIC Cell Line Gene Mutation Profiles 1.0 null D425 DepMap CRISPR Gene Dependency 1.0 3.677 mucosa TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.471927 Diabetic ketoacidosis DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.055 membrane part COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.098109 BRD-K14255526 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24696 IZ in orbital frontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.825611 positive regulation of nitrogen compound metabolic process GO Biological Process Annotations 2015 1.0 null Bronchoalveolar system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.905 layer III of rostral entorhinal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.847979 subgranular zone of caudal dentate gyrus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.12182 PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR Rummagene Transcription Factor Associations 2026 1.0 null BRD-K21206585 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.04427 Generalized anxiety disorder DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.229 A427 COSMIC Cell Line Gene Mutation Profiles 1.0 null RMUG-S Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.965522 BRD-K69922285 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.79558 OCI-AML2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.88117 chromosome, subtelomeric region COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.831 estradiol_homo sapiens_gpl570_gds3283 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null outer CP in midinferior temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.1613 CRCGN014_HEPG2_24H:N04 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 7.8095 CRCGN015_HEPG2_48H:H01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.51542 HCC1569 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.498575 BRD-A10417568 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.55428 clofibrate-444 CMAP Signatures of Differentially Expressed Genes for Small Molecules -1.0 null positive regulation of purine nucleotide metabolic process GO Biological Process Annotations 2015 1.0 null Orbital area, ventrolateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.05444 GI-ME-N GDSC Cell Line Gene Expression Profiles -1.0 -1.87156 intermediate stratum of r10Tr Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60222 BRD-K91596921 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.40962 anterior (rostral) cingulate (medial prefrontal) cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.55994 VZ in caudal hippocampal proper Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -2.00679 FOXO4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.3581 trace-amine receptor activity GO Molecular Function Annotations 2023 1.0 null neuroactive ligand receptor interaction KEGG Pathways 1.0 null OE33 CCLE Cell Line Gene Expression Profiles 1.0 1.37106 IX, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -1.89767 r8 part of basolateral reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.06142 orbital frontal cortex_37 yrs_M_12303 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.48022 dorsolateral prefrontal cortex_16 pcw_M_12287 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.915674 ZFP42 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 24.2432 Hemolymph TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.97 CRCGN014_HEPG2_3H:C10 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.01116 receptor activity GO Molecular Function Annotations 2015 1.0 null PMC3573729-nl3042917_si_005.xlsx-OWY_Overlap_with_ANOVA-YOUNG_NANOG_NANOG Rummagene Transcription Factor Associations 2026 1.0 null SP in midlateral temporal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.23279 BRD-K69659917 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03967 plant-type vacuole membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.885 Neural arch TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.885 CRCGN015_MCF10A.TP53.M_24H:C21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.4587 nucleus of the inferior collicular brachium, rostral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.15724 NANOG-19829295-ESCS-HUMAN ChEA Transcription Factor Targets 2022 1.0 null SG in frontal polar cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.53542 SBC-5 COSMIC Cell Line Gene Mutation Profiles 1.0 null KMS-27 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3286 Anterior olfactory nucleus, lateral part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.0941 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null layer 1 of LOT Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.68712 BRD-K37763427 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.29916 anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.13421 CRCGN009_HEPG2_24H:D05 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.49785 Bed nuclei of the stria terminalis, anterior division, fusiform nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.55246 amines GeneRIF Biological Term Annotations 1.0 null positive regulation of nucleobase-containing compound metabolic process GO Biological Process Annotations 2015 1.0 null precommissural nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.967635 HNT34 CCLE Cell Line Gene CNV Profiles -1.0 -1.36911 BRD-K63743653 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10472 dorsomedial hypothalamic nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.913379 Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JF-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null TM-3 cell TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.02 ligands GeneRIF Biological Term Annotations 1.0 null Habenula TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.059 BRD-K77223020 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.02051 haloperidol-6203 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null HCC1599 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.95209 MDAMB361 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.64299 BRD-K98161738 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.68127 CRCGN015_MCF10A.TP53.M_24H:P15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.1645 dorsolateral prefrontal cortex_12 pcw_F_12960 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.5477 E2F3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1772 CRCGN009_HEPG2_24H:H15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.84255 positive regulation of cellular biosynthetic process GO Biological Process Annotations 2015 1.0 null LBP-1 MotifMap Predicted Transcription Factor Targets 1.0 null BRD-K66016089 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.39458 Dorsal striatum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.79 NCI-H1781 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 0.852638 HA1E DepMap CRISPR Gene Dependency 1.0 2.72198 CRCGN015_MCF10A.WT.HP_24H:O12 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.07086 BRD-K91421454 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.28052 Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4814-01A-01R-1277-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K55679243 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.20429 primary auditory cortex (core)_21 pcw_F_12365 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.22234 BRD-K69347147 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.24492 SNU-81 COSMIC Cell Line Gene Mutation Profiles 1.0 null G118 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.1264 SW 403 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.26344 H3K27me3_IMR90 Roadmap Epigenomics Histone Modification Site Profiles 1.0 null periventricular stratum of VTTh Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.52963 HCT-15 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K36237864 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.19133 BRD-K05286676 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.1095 SKMEL5 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.0013 anterior (rostral) cingulate (medial prefrontal) cortex_1 yrs_F_12830 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.06175 G protein-coupled receptor dimeric complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.775 BRD-K79213964 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.46088 FOXB1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 33.7322 ventrolateral prefrontal cortex_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.882848 caudal presubiculum (postsubiculum) Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -1.99602 ventral lateral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.22534 BRD-K06846146 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.03837 LN382 Achilles Cell Line Gene Essentiality Profiles 1.0 2.29916 Olfactory nerve TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.416 intermediate stratum of APal Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.12709 cell COMPARTMENTS Curated Protein Localization Evidence Scores 1.0 0.663342 MEOX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.6054 BRD-K42526449 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.71563 BARX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.1471 positive regulation of cyclic nucleotide metabolic process GO Biological Process Annotations 2015 1.0 null olfactory GeneRIF Biological Term Annotations 1.0 null TRMT11 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 3.2267 Zfp335 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 22.2857 Signal Transduction Reactome Pathways 2024 1.0 null regulation of nucleobase-containing compound metabolic process GO Biological Process Annotations 2015 1.0 null positive regulation of biosynthetic process GO Biological Process Annotations 2015 1.0 null BRD-K68160857 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.13747 TE15 Achilles Cell Line Gene Essentiality Profiles 1.0 2.24552 Nutrition disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.114 OCI-M2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.35335 Brain Lower Grade Glioma_LGG_TCGA-TM-A7C3-01A-11R-A32Q-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null mRNA_KLF4_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.50243 SIX1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.8836 mantle zone of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 2.00229 BRD-K09641927 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.3271 Generalized epilepsy with febrile seizures plus 6 DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.645 Olfactory cortex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.992 PMC8104016-hcg-12-e002353-s006.xlsx-mTHP-1-LPS_Prom-Prom_Prom-GWAS-RefSeq_Name_1_IRF6 Rummagene Transcription Factor Associations 2026 1.0 null BRD-K14163107 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35456 G-401 GDSC Cell Line Gene Expression Profiles 1.0 1.4247 BRD-K17675924 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.59077 positive regulation of purine nucleotide biosynthetic process GO Biological Process Annotations 2015 1.0 null BRD-K22390389 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06533 Glycine reductase complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.029 nucleus of the lateral olfactory tract Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11212 NCI-H1703 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K34701680 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.39062 ZNF384 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 118.606 H3K27me3_mononuclear cell_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null r10 part of external cuneate nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.1792 LN340 Achilles Cell Line Gene Essentiality Profiles 1.0 1.08899 dorsolateral prefrontal cortex_4 yrs_M_12298 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 2.12739 perspective GeneRIF Biological Term Annotations 1.0 null BRD-K69528787 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02566 Prostate adenocarcinoma_PRAD_TCGA-VP-A872-01A-11R-A352-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null JHOM1 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.80597 LNZ308 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.96278 MAF::NFE2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.0633 r10 part of dorsal parvicellular reticular formation Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.60327 ZR751 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles -1.0 -1.27416 Kidney renal papillary cell carcinoma_KIRP_TCGA-DW-5560-01A-01R-1592-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null regulation of cyclic nucleotide metabolic process GO Biological Process Annotations 2015 1.0 null III, left, lateral hemisphere Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles -1.0 -0.895456 pineal_day BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 0.834059 BRD-K84241565 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 4.26686 496100294_HIP_possible Alzheimer's disease_TBI_90-94_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.02535 BRD-K07836769 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29666 ZNF667 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 21.4385 PIAS1_KD_GSE44024_133_human_breast cancer cells GEO Signatures of Differentially Expressed Genes for Gene Perturbations 1.0 null BRD-K78337983 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.64906 BRD-K81124412 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29813 CRCGN015_MCF10A.WT.HP_24H:G15 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.77285 BRD-K84423439 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.06481 DBP JASPAR Predicted Human Transcription Factor Targets 2025 1.0 27.0604 BRD-K17065706 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.17757 oval paracentral nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25038 dexamethasone_homo sapiens_gpl6244_gse20963 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null KU812 CCLE Cell Line Gene CNV Profiles 1.0 1.40037 HCC70 Achilles Cell Line Gene Essentiality Profiles -1.0 -1.04794 BRD-K55569103 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.09276 Dorsal raphe nucleus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.247 ZNF85 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 36.988 HEC265 CCLE Cell Line Gene Expression Profiles 1.0 2.17152 acacetin-3942 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null BRD-K72071403 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.19469 Claustrum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.817 BRD-K67229323 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.12639 SOX18 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 16.7228 COLO704 Achilles Cell Line Gene Essentiality Profiles 1.0 1.25714 r1 roof plate Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.71052 G402 CCLE Cell Line Gene Expression Profiles 1.0 1.5779 periventricular stratum of r5Co Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11699 BRD-K29253960 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.08475 CRCGN015_MCF10A_48H:G01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.5801 Brain Lower Grade Glioma_LGG_TCGA-E1-A7YW-01A-11R-A34R-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null Serotonin receptor complex COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.336 SNU-175 COSMIC Cell Line Gene Mutation Profiles 1.0 null BRD-K84278600 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.54636 mRNA_NR5A2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null Olfactory glomerulus TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.375 r7 part of rostral ventromedial reticular area Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.92236 BRD-K33217094 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.58268 CRCGN017_MCF10A.WT.HP_24H:P24 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.013 IOMMLEE Achilles Cell Line Gene Essentiality Profiles 1.0 1.46266 BRD-K44078665 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15642 BRD-K59587063 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18404 Dendritic branch COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.884 CRCGN010_HEPG2_24H:D01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.73923 BRD-K09895564 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.8378 TBXT JASPAR Predicted Human Transcription Factor Targets 2025 1.0 18.4528 posteroventral (inferior) parietal cortex_40 yrs_F_12304 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.54083 SW1710 COSMIC Cell Line Gene Mutation Profiles 1.0 null periventricular stratum of p3ZL Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.96555 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-ENSEMBL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null CRCGN015_MCF10A_48H:M07 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 8.14326 BXPC3 Achilles Cell Line Gene Essentiality Profiles 1.0 1.01509 Brain Lower Grade Glioma_LGG_TCGA-HT-8110-01A-11R-2404-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null AtrioventricularNode BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 2.2603 Inflorescence apex TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.881 ACN GDSC Cell Line Gene Expression Profiles -1.0 -1.45434 positive regulation of camp metabolic process GO Biological Process Annotations 2015 1.0 null VCAP COSMIC Cell Line Gene Mutation Profiles 1.0 null intermediate stratum of r10BM Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.38785 BRD-K84879982 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.36292 CRCGN014_HEPG2_24H:H18 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.10427 TMD8 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.33311 BRD-K26526202 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.29001 Trimethylaminuria DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.501 GM1600 BioGPS Cell Line Gene Expression Profiles 1.0 1.00694 Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A5Y1-01A-11R-A28H-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K63579322 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.84524 butacaine-5748 CMAP Signatures of Differentially Expressed Genes for Small Molecules 1.0 null SIX2 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 48.5595 regulation of camp biosynthetic process GO Biological Process Annotations 2015 1.0 null CRCGN014_HEPG2_3H:C14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures -1.0 -2.07434 anterior tegmental nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.31696 CRCGN015_MCF10A_48H:H03 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.41427 BRD-K43449580 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.02109 YY1 MotifMap Predicted Transcription Factor Targets 1.0 null C bouton COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.606 RPMI8226 CCLE Cell Line Gene Expression Profiles 1.0 1.3866 BRD-K43639523 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.4604 GPCRs, Other(Homo sapiens) WikiPathways Pathways 2014 1.0 null Mesaxon COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 1.002 BRD-K68300789 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.13483 HCC1954 Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 0.621988 BRD-K78748401 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.9669 BRD-K79437066 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.2031 primary auditory cortex (core)_16 pcw_M_12879 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.00064 molecular_function GO Molecular Function Annotations 2015 1.0 null rhombomere 10 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.03488 SNUC5 DepMap CRISPR Gene Dependency 1.0 3.00315 DU4475 CCLE Cell Line Gene Expression Profiles 1.0 1.93046 KP2 CCLE Cell Line Gene CNV Profiles -1.0 -1.36621 ChIP_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null CRCGN015_HEPG2_48H:G13 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.27515 Ventral medial nucleus of the thalamus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.33516 NANOG-18692474-MESCS-MOUSE ChEA Transcription Factor Targets 2022 1.0 null Orbital area, lateral part, layer 6a Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.25336 BRD-K06900263 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.70632 lateral habenular nucleus, left Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles 1.0 1.12863 RBM28 CM4AI KOLF21J CRISPRi Gene Perturbation Atlas 1.0 2.13269 Preeclampsia_Placenta_GSE4707 GEO Signatures of Differentially Expressed Genes for Diseases -1.0 -1.61683 BRD-K76861469 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.58425 superficial stratum of r8BI Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.31143 KP-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.95774 HNT-34 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.3286 CRCGN016_MCF10A.WT.HP_24H:C21 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 4.52414 Lateral reticular nucleus, parvicellular part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.27163 BRD-K73494324 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.68888 CRCGN015_MCF10A_48H:P06 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.67495 BRD-K71647210 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.34915 Trichome TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.815 Mesolimbic dopaminergic system TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.599 GCT GDSC Cell Line Gene Expression Profiles 1.0 1.46983 mRNA_GATA3_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null SOX15 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.4991 superficial stratum of CoPV Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18034 HOXA4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 19.5418 outer SZ in medial temporal-occipital cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.989901 KURAMOCHI CCLE Cell Line Gene Expression Profiles -1.0 -1.77511 C3A Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.00944 Amine ligand-binding receptors Reactome Pathways 2014 1.0 null CRCGN014_HEPG2_3H:O01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.08637 previous GeneRIF Biological Term Annotations 1.0 null KMS-28PE Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.10585 BRD-K71870778 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.76357 brain GeneRIF Biological Term Annotations 1.0 null MedullaOblongata BioGPS Human Cell Type and Tissue Gene Expression Profiles -1.0 -1.16731 IZ in dorsolateral prefrontal cortex Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 2.47921 Axon hillock COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025 1.0 0.977 spinal (inferior) vestibular nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 0.835669 BRD-K96510191 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.10991 FOXP3 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 14.9276 BRD-K33748896 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.81624 integral component of membrane COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.237401 496100514_FWM_no dementia_TBI_95-99_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.707 r5 part of dorsal cochlear nucleus Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.11664 OV-90 COSMIC Cell Line Gene Mutation Profiles 1.0 null CRCGN015_MCF10A_48H:J22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 6.1273 G protein-coupled amine receptor activity GO Molecular Function Annotations 2023 1.0 null COLO 792 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14763 CRCGN015_MCF10A_48H:H22 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.69841 ventrolateral prefrontal cortex_16 pcw_M_12837 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.17616 accessory entopeduncular nucleus (post-migratory) Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.58583 Brain Lower Grade Glioma_LGG_TCGA-DU-7292-01A-11R-2027-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null RCOR1-19997604-NEURONS-MOUSE ChEA Transcription Factor Binding Site Profiles 1.0 null CRCGN016_MCF10A.WT.HP_24H:M01 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 3.0523 SUM102PT Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles 1.0 1.29963 signal transducer activity GO Molecular Function Annotations 2015 1.0 null Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4989-01A-01R-1334-07 TCGA Signatures of Differentially Expressed Genes for Tumors 1.0 null BRD-K80469338 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.25099 GATA3_MCF-7_hg19_1 ENCODE Transcription Factor Binding Site Profiles 1.0 null 23132-87 COSMIC Cell Line Gene Mutation Profiles 1.0 null Nr2e1 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 24.6294 ventrolateral prefrontal cortex_12 pcw_F_13060 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 0.846891 ChIP_NANOG_18347094 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null regulation of phosphate metabolic process GO Biological Process Annotations 2015 1.0 null H3K27me3_CD4+ CD25- CD45RO+ Memory Primary Cells Roadmap Epigenomics Histone Modification Site Profiles 1.0 null BRD-K00083518 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.00569 LN-229 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.14763 Primary visual area, layer 2/3 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.37145 SOX9 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 17.4211 LAMA84 CCLE Cell Line Gene CNV Profiles 1.0 1.58822 CP in rostral hippocampus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles 1.0 1.32993 BRD-K72161690 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.06314 tissues, cell types and enzyme sources TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.052661 Accessory olfactory bulb TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 1.991 PMC4029819-pone.0098069.s005.xlsx-FOXA1-Table_S4_FSS_analysis_of_FOXA1_high_versus_FOXA1_low_cases_in_ER_negative_samples_p-value_0_01_FOXA1 Rummagene Transcription Factor Associations 2026 1.0 null UT7 CCLE Cell Line Gene CNV Profiles 1.0 1.83279 HS852T CCLE Cell Line Gene CNV Profiles -1.0 -1.42689 TE8 CCLE Cell Line Gene Expression Profiles -1.0 -1.48132 BRD-K28795679 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.34111 TCF7 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 40.1738 CRCGN015_HEPG2_48H:G14 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 5.96066 receptors GeneRIF Biological Term Annotations 1.0 null RERFLCSQ1 DepMap CRISPR Gene Dependency 1.0 2.29514 BRD-K35193502 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.87523 Subiculum TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.811 Catecholaminergic neuron TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.759 NCIH1650 CCLE Cell Line Gene CNV Profiles -1.0 -1.42244 MAFG::NFE2L1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 22.4338 SK-MM-2 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -1.28904 doxycycline_mus musculus_gpl2872_gse33875 GEO Signatures of Differentially Expressed Genes for Small Molecules 1.0 null mRNA_MYCN_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells -1.0 null Synucleinopathy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.292 NCI H226 BioGPS Cell Line Gene Expression Profiles 1.0 0.868307 BRD-K54934070 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.18278 BRD-K47724892 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.39287 CRCGN016_MCF10A.TP53.M_24H:O11 Carcinogenome Chemical Perturbation Carcinogenicity Signatures 1.0 2.2469 lateral septal nucleus Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles -1.0 -0.924024 BRD-K63754039 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.05849 HSF1 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 25.437 YMB-1-E Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles -1.0 -0.852025 SNB19 BioGPS Cell Line Gene Expression Profiles -1.0 -0.9875 SCC-3 Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles 1.0 1.53787 PMC8202205-NIHMS1706275-supplement-Table_S1.xlsx-Def_End_D4_GATA6-dependent-SYMBOL_GATA6 Rummagene Transcription Factor Associations 2026 1.0 null pyrazinamide_mus musculus_gpl6246_gse48027 GEO Signatures of Differentially Expressed Genes for Small Molecules -1.0 null Posterolateral visual area, layer 1 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.02035 mRNA_CDX2_19796622 ESCAPE Omics Signatures of Genes and Proteins for Stem Cells 1.0 null DKMG CCLE Cell Line Gene CNV Profiles -1.0 -1.48267 HSF4 JASPAR Predicted Human Transcription Factor Targets 2025 1.0 30.5119 BRD-K68618340 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15197 BRD-K69337311 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.43767 taar GeneRIF Biological Term Annotations 1.0 null Orbital area, lateral part, layer 5 Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.57975 lung TISSUES Text-mining Tissue Protein Expression Evidence Scores 1.0 0.220378 Appendix BioGPS Human Cell Type and Tissue Gene Expression Profiles 1.0 1.17124 SNU601 CCLE Cell Line Gene CNV Profiles 1.0 1.40605 Taste bud TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025 1.0 0.69 superficial stratum of r10Ve Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles 1.0 1.18149 cell part COMPARTMENTS Text-mining Protein Localization Evidence Scores 1.0 0.040178 positive regulation of nucleotide biosynthetic process GO Biological Process Annotations 2015 1.0 null BRD-K54484272 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.17411 naltrindole-hcl LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.26079 BRD-K10460649 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.15863 inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_12835 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.3969 Narcolepsy DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.194 primary motor cortex (area M1, area 4)_13 pcw_M_12888 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray -1.0 -1.0772 interstitial nucleus of the zona limitans Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -2.38792 PANC0213 CCLE Cell Line Gene Expression Profiles -1.0 -1.55271 positive regulation of cyclic nucleotide biosynthetic process GO Biological Process Annotations 2015 1.0 null primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836 Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray 1.0 1.03779 BRD-K91039552 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures 1.0 3.35055 496100317_FWM_no dementia_no TBI_81_M Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles 1.0 2.57508 BRD-K07588901 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -3.22953 BRD-K57315740 LINCS L1000 CMAP Chemical Perturbation Consensus Signatures -1.0 -4.21663 substantia innominata/basal nucleus, transitional part Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles -1.0 -1.01639 Rhox11 JASPAR Predicted Mouse Transcription Factor Targets 2025 1.0 23.921 Disease DISEASES Text-mining Gene-Disease Association Evidence Scores 2025 1.0 1.763