association	dataset	threshold value	standardized value
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
GSE145915_5_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE202284,GSE202289_5_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CUX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4471
Avian pallium	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SAFB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06829
GSE84922,GSE84924_4_v_1_sall4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TJAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.26223
Hmx3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0481
SLC1A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32578
NR3C1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.94227
Internal capsule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.803
CDC25C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.5628
GSE196540,GSE196542_2_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196540,GSE196542_4_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mouse - Motor Cortex - Cluster - Layer 5 glutamatergic neuron, extratelencephalon-projecting_2	HuBMAP Azimuth Cell Type Annotations	1.0	null
EDRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80104
ARMC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67096
GSE175787_4_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pontine nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.839
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4366
Specific developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.263
Stat4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.1455
BEND5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60247
MIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84299
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POU2F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.9357
PMC9235320-mmc2.xlsx-ST9_eQTL-MR-results-Unnamed_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PDF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73727
SLC12A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10265
UBE2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.90552
TJP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0452
VPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28196
SLC30A7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36936
LRRC26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13441
GSE138001_2_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE115542_5_v_0_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Telencephalon	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PLAG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03544
GSE210093_3_v_2_taf15_human	RummaGEO Gene Perturbation Signatures	1.0	null
Habenular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.007
GSE211177,GSE211178_0_v_1_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.5948
GSE89057_0_v_1_sox5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Basal ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE224096_2_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
REL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5882
GSE207433_2_v_3_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NEURL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87683
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	53.9368
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.7056
GSE196540,GSE196542_2_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE155800_1_v_0_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TSN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36057
RAVER1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0639
PBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.5709
Mouse - Motor Cortex - Cross-Species Cluster - Layer 5 glutamatergic neuron, extratelencephalon-projecting_1	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE149075_2_v_0_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr3_68438533_A_G_b38	GTEx eQTL 2025	1.0	2.80578
PAK1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97385
GSK3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11904
Subiculum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.041
MTO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72943
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of neuroblast proliferation	GO Biological Process Annotations 2025	1.0	null
ZNF148	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39216
PSMA4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73528
ZNF542P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15516
P2RY2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92601
DGCR6L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84243
NFIL3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7487
hyperactivity	IMPC Knockout Mouse Phenotypes	1.0	null
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3017
GSE195786_0_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SLC45A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01445
RARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	52.7826
NTMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.363
Mouse - Motor Cortex - Cross-Species Cluster - Sncg+ GABAergic neuron_4	HuBMAP Azimuth Cell Type Annotations	1.0	null
PMC13000489-mmc1.xlsx-Table_S3-Table_S3_LC_related_genes_screened_by_MR_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
HELQ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05318
DEPDC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42837
Lateral amygdaloid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.455
FOXK2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6405
Integrin alpha7-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.103
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16173
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Amygdala	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE118816_2_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7435699-mmc5.xls-Gene_lists-MITF_ChIP_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.0399
RBM33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.16694
GSE65617_2_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF517	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04423
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Extracellular space	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
LZIC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33725
MVK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.62731
Colonic neuron_Dorsal root ganglia_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
RAD9A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27453
LITAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31794
ZKSCAN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.5582
CCNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51545
RPL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72383
ALDH9A1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37329
FKTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.72192
SPPL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14789
UBXN2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.02897
RNF25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20591
MYO18A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01838
NR1I2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1278
GSE180813,GSE180815_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZDHHC24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43499
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
laminin-2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.907
Stat2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	61.1965
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE196318_0_v_1_xpo4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HMGN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56944
NDST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7778
CPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83673
GSE145323,GSE145324_3_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12717993-MEC-34-e17796-s002.xlsx-ST12_WGS_RFMix_genes_2_anc-Unnamed_14_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE101239_5_v_6_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lateral dorsal nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.215
496100562_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.39394
PTPRZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10739
GEMIN8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39549
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.2245
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin - Not Sun Exposed (Suprapubic)	GTEx Tissue Gene Expression Profiles 2023	1.0	4.56622
Basal labyrinth	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.985
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.08615
TFAP2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05772
GSE174498,GSE174500_2_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PROP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.44557
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
496100554_FWM_no dementia_no TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.39798
CEP192	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.13306
ipc298	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.742
DPM3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.80575
GSE201217_4_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101239_3_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12315868-Supplemental_Data_S1.xlsx-Supplemental_Data_S1F-TP53_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
GTPBP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21346
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.2402
Dlx5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.9637
GSE210580_0_v_2_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Superior temporal sulcus banks volume	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
Inhibitory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.681
GEM	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.39144
Compact myelin	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.865
GSE196117_1_v_11_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Spatial memory	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.51549
Ventral aorta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.639
Habenula	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.084
Stat5a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.2663
Oogenesis phase fetal germ cell_Fetal gonad_Human	CellMarker Gene-Cell Type Associations	1.0	null
DNALI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.75992
non-neuronal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.41
PMPCA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.50217
GSE145915_3_v_2_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Sympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.77
GSE210580_4_v_6_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nucleus preopticus medialis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.979
NELFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.49854
EIF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80291
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
NFATC4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.7011
LSM8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29694
CDX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3692
WDR89	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.08218
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.1045
GSE197117_0_v_1_kdm6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prelimbic cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.107
Endostyle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.693
USP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07256
FEZ2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73834
GSE185944_0_v_1_pth1r_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196540,GSE196542_2_v_5_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SREBF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.4035
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.8727
ENDOD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6222
DLGAP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.2907
KCNQ4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.21059
Lateral habenular nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.327
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DPY19L4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53082
496100577_FWM_probable Alzheimer's disease_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37555
Limbic system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Dinoflagellate cingulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.692
GPATCH4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74828
APC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26958
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.1758
QARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09249
TAOK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.85003
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CENPJ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62373
ATF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49317
GSE93918_2_v_3_clozapine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Integrin alpha3-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.68
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.3889
neuroblast differentiation	GO Biological Process Annotations 2025	1.0	null
Williams-Beuren syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.226
Ventromedial hypothalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.841
Mouse - Motor Cortex - Subclass - Layer 2-3 glutamatergic neuron, intratelencephalon-projecting	HuBMAP Azimuth Cell Type Annotations	1.0	null
Neuron projection branch point	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
NR2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.5354
PMC8844187-Table_2.xlsx-prostate-DLX1_DLX1	Rummagene Transcription Factor Associations 2026	1.0	null
SMARCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26545
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Gene_Name_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Human - Motor Cortex - Subclass - Layer 2-3 glutamatergic neuron, intratelencephalon-projecting	HuBMAP Azimuth Cell Type Annotations	1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Central nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.172
PMC11953390-41598_2025_94761_MOESM1_ESM.xlsx-Table_S3-Table_S3_The_result_of_MR_analysis_and_sensitivity_analysis_for_CKD_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE60217_1_v_0_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11111877-41598_2024_62256_MOESM7_ESM.xlsx-Table_S1-Supplementary_Table_S1_The_intersect_genes_of_AR_and_RNA_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE188870,GSE188871_4_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9385264-NIHMS1828071-supplement-8.xlsx-ESR1-gene_symbol_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Panic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
GSE211744_2_v_4_gdf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Intercalated cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.653
MICA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78811
NR1H2::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.0
GSE189653,GSE203344_2_v_1_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4858740-ncomms11473-s2.xls-HAdV-D9_Cr1b_Library_2-Hit_name_CENPX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE187006_3_v_2_valproic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CERS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37276
FOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0913
ZBTB7A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73625
GSE224096_3_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210682_2_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210580_0_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RPS24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11282
TRMT2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.42702
ZNF532	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18347
USP22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44347
PMC6499311-supp_gr.243345.118_Supplemental_Table_S8.xlsx-S8C_Het1A-HNF4A_2d_5x_closed-Nearest_Ensembl_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
496100436_FWM_no dementia_no TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.36686
GSE234340_4_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196540,GSE196542_4_v_3_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NUDT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2655
MKKS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32175
NKX2-8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6871
Neurodegenerative disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.023
ERCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67397
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_60_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Enteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.552
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
Aniridia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.024
Urinary tract	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RASL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27169
RNF149	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59413
ATF4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.0377
Postcentral gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.116
High vocal center	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.996
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-SYMBOL_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
TRAPPC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.20013
MAU2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70755
NUB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.7888
CCNH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8181
GSE60217_1_v_10_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148252_0_v_6_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dendritic branch point	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.585
SMDT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75024
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TMTC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68082
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.3174
VPS36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.79527
PMC7582185__F4	PFOCR Pathway Figure Associations 2024	1.0	null
Claustrum	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.063
163 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.633
chr3_68057785_C_T_b38	GTEx eQTL 2025	1.0	1.09055
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_and_sensitivity_analysis_for_IPF_susceptibility_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
NOC4L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23057
GSE210682_0_v_3_methadone_human	RummaGEO Drug Perturbation Signatures	1.0	null
DMRTC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.4365
DDX47	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03932
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-version_2_4_AR	Rummagene Transcription Factor Associations 2026	1.0	null
LHX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14216
GSE194396,GSE194429_1_v_0_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140200_1_v_0_trim59_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaDadj_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199606_2_v_7_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Cortical amygdaloid nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.384
PMC7439574-13148_2020_914_MOESM2_ESM.xlsx-log2_fold_change_-2-1280_genes_are_more_than_four-fold_downregulated_in_PRDM8-_-_compared_to_control_PRDM8	Rummagene Transcription Factor Associations 2026	1.0	null
RPL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01366
TLCD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20911
PRPF40A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1541
PMC9950457-mmc3.xlsx-GRHL2_binding_sites-RBBP8NL_GRHL2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174498,GSE174500_5_v_8_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CCDC86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22626
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.26257
496100532_FWM_no dementia_no TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.4406
FITM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69336
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU2F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.4253
RIF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21033
GSE142019,GSE142021_10_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148252_0_v_4_npas4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100484_FWM_no dementia_no TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.25312
Ganglion	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE210093_0_v_2_taf15_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE145915_3_v_4_pcm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MPHOSPH10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11138
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PODXL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08513
PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
COG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46436
GSE90821_3_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.028
HOXD9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5961
Laterodorsal thalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.685
Granule cell layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.985
Lateral posterior nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.053
Type I terminal bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.502
RPP38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47311
Amyotrophic lateral sclerosis (sporadic)	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.639794
MAP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1639
GSE219195_1_v_2_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21162
PMC11185762-media-2.xlsx-ATAC2wk_KD_V337M_intersect_peak-Symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PHLDA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35552
GSE224556,GSE224557_6_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MGA::EVX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5101
FXN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68721
GSE196117_6_v_11_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Muscular dystrophy-dystroglycanopathy	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.283
Choanal atresia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.228
HLF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.4505
GABA-ergic synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.304
TMCO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58625
EMG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04393
GSE120248,GSE120252_1_v_0_macf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GRAMD1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43987
GSE200352_5_v_0_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HIKESHI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.19981
TBC1D14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00684
Medial mammillary nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.012
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
THBS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37209
ADAMTS8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08344
FOXO4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29984
MED13L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47573
NR3C1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3793
SLX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.69453
CEBPG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.8999
496100391_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.53078
NKG7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62527
laminin-5 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.771
PMC9170821-JCMM-26-3183-s001.xlsx-Astro_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8444148-NIHMS1529754-supplement-1529754_Tab_S2.xlsx-upregulated_in_ATF4OE_txt-RNA-seq_of_C3_ATF4_OE_and_C3_neurons_ATF4	Rummagene Transcription Factor Associations 2026	1.0	null
GATA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.94399
NME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09511
FAM117B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32744
PLBD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27447
POU3F2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7349
Cranial ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.698
TBR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7292
YAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.40189
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-GENE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149903_3_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE174498,GSE174500_5_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158431_2_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE255432_6_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE137954_4_v_2_smyd3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mouse - Motor Cortex - Subclass - Layer 5 glutamatergic neuron, extratelencephalon-projecting	HuBMAP Azimuth Cell Type Annotations	1.0	null
CABLES1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9927
RBBP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09751
Mouse - Motor Cortex - Cluster - Lamp5+ Egln3+ GABAergic neuron_1	HuBMAP Azimuth Cell Type Annotations	1.0	null
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.59582
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S1-Table_S1_Instrumental_variables_used_in_MR_analysis_of_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF35	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1665
GSE166315_1_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Histaminergic neuron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.913
PMC12019518-ao5c02459_si_002.xlsx-Table_S3-Table_S3_Screening_of_genes_that_are_commonly_upregulated_in_cells_on_stiff_substrate_and_down-regulated_by_KD_of_UBE2A_B_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125486_0_v_1_rprd1b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE249714_0_v_1_anxa1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Subsynaptic reticulum	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.502
NPM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.88296
GSE149903_4_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE101112_0_v_2_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TRIO	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.70273
GSE81803,GSE81912_3_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
LGALS3BP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32697
GSE228894_0_v_1_rnmt_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE138019_3_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4269325-NIHMS634665-supplement-supp_table4.xls-H3K27me3_TRIM37_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
COG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.76901
GSE135350_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MEAF6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.299
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CCT6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51436
Trigeminal ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.705
C3orf14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10912
MTERF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08256
USHBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.78411
PTGFRN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26532
COX5A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21671
GSE196540,GSE196542_4_v_5_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6084392-oncotarget-09-30253-s006.xls-geneset2-TF-miRNA-net-GFI1_GFI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202310_1_v_0_ube3d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100549_FWM_no dementia_TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.13405
Mouse - Motor Cortex - Cluster - Layer 5 glutamatergic neuron, extratelencephalon-projecting_3	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE114883_1_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Somatosensory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.14
DNASE1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3246
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.2671
Cerebral lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC10915192-ab-23-0304-Supplementary-Table-S7.pdf-17-MEIS2_MEIS2	Rummagene Transcription Factor Associations 2026	1.0	null
AFG3L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08998
CD81	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45201
Nidopallium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.952
Hmx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	33.3222
C bouton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.806
ETV5::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3644
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.46244
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-SOX4-toNode_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
Striate cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.107
Distal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.791
CPSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14996
L-6 myoblast cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.06
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S5-Table_S5_The_result_of_MR_analysis_and_sensitivity_analysis_for_FVC_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_HA-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
COX10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.85333
INPP5E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25857
MEIS2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.9201
GSE220520_3_v_4_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_SBP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11385078-jciinsight-9-172336-s272.xlsx-1DEseq2_Report_AA_BL_vs_EA_BL-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
WBP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.47311
Human - Motor Cortex - Subclass - Layer 5 glutamatergic neuron, extratelencephalon-projecting	HuBMAP Azimuth Cell Type Annotations	1.0	null
PMC11522423-41598_2024_76982_MOESM1_ESM.pdf-28-ZNF491_ZNF491	Rummagene Transcription Factor Associations 2026	1.0	null
SLC1A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10132
ZNF652	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9284
POLR2J	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65631
Disease of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.376
CLIC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30595
Hmx1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.3585
Foxl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9044
receptor ligand activity	GO Molecular Function Annotations 2025	1.0	null
AKAP8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93167
PMC12000322-41419_2025_7601_MOESM9_ESM.xlsx-H3122-AR_somatic_filtered_PASS-Unnamed_47_AR	Rummagene Transcription Factor Associations 2026	1.0	null
MRPS25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24355
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dlx2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.7487
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
EXOSC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.86096
YIPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08829
GSE173201_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB37	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20109
GSE121043_0_v_1_aldh1a1_human	RummaGEO Gene Perturbation Signatures	1.0	null
PRPF39	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.9343
PMC12478325-12672_2025_3468_MOESM1_ESM.xlsx-Table_S9-Table_S9_Results_of_MR_analysis_between_druggable_genes_eQTLs_and_CrNEN_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H2BC12L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.16519
NKAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27651
Anterior olfactory nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.959
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	3.77976
PEX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77889
CEBPA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5358
GSE175787_5_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
DSN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.56553
ANKRD28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.31679
GSE146894_3_v_8_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lateral geniculate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.666
Entorhinal area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.544
AIRE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65562
GSE210580_0_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BMI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.51158
GSE224556,GSE224557_8_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.7341
MID1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06925
Mouse - Motor Cortex - Cluster - Layer 5 glutamatergic neuron, extratelencephalon-projecting_1	HuBMAP Azimuth Cell Type Annotations	1.0	null
Corpus albicans	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.793
MEF2B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	39.0797
FOXN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.5615
JUN::JUNB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.5639
Mouse - Motor Cortex - Cluster - Layer 2-3 glutamatergic neuron, intratelencephalon-projecting_1	HuBMAP Azimuth Cell Type Annotations	1.0	null
Acrodermatitis chronica atrophicans	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.089
USP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25178
STAP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19749
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100455_FWM_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37863
chr3_68438133_C_A_b38	GTEx eQTL 2025	1.0	1.64729
496100346_FWM_no dementia_TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.42482
PARP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44609
RPP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.44798
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.79969
RGL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25122
Developmental disorder of mental health	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.394
GSE174498,GSE174500_2_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ITM2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01999
496100362_FWM_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.5243
OLFML2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.54889
Intellectual disability	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.188
TES	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16584
GSE206870,GSE206872_1_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174498,GSE174500_5_v_1_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE205070_1_v_6_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RARA::RXRG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9065
TXK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.3038
ETNK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15745
PMC9170821-JCMM-26-3183-s001.xlsx-Neu_DAPI_ERG_VaD_vs_NC-Gene_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9841165-mmc2.xlsx-GSC-Glioma_Stem_Cell_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
496100367_FWM_no dementia_TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37274
GSE207832_1_v_0_usp22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TELO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8273
RAB3GAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27884
GSE184210_0_v_2_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF184	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1828
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CCDC88A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14703
SLC16A14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33497
EPB41L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51854
PGBD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42181
UTP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90841
POU3F2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.63321
ERCC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31894
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3194
GSE138001_0_v_3_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11993713-41598_2025_96655_MOESM1_ESM.xlsx-S10-Table_S10_MR_results_of_the_discovery_blood_cis-eQTLs_and_Sepsis_outcomes_in_IVW_or_Wald_ratio_methods_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
COPS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15328
FOXD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35415
GSE94011_0_v_3_pias3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ACSL4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83744
GSE203308_7_v_5_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF488	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87676
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8A-MLX_3T3_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
GSE210580_0_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleus preopticus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.817
NAA16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59381
SH2D3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.36544
PMC11913834-Table2.xlsx-CEBPB_bound_geneset-Gene_CEBPB	Rummagene Transcription Factor Associations 2026	1.0	null
BICRA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07346
GSE158431_5_v_1_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6938365-pone.0226733.s019.txt--MAFK_MAFK	Rummagene Transcription Factor Associations 2026	1.0	null
Foxn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.6458
GPANK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.42218
Brush cell (Tuft cell)_Intestinal crypt_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
VPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04699
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KLK6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22816
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2273
TET2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09274
PMC9235320-mmc2.xlsx-ST9_eQTL-MR-results-Supplementary_Table_9A_The_effects_of_whole_blood_transcripts_on_COVID-19_severity_with_suggestive_Mendelian_randomization_evidence_P_0_05_using_Genomicc_data_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Habenular trigone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.007
HOXA10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.6899
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.2433
HSPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.28655
TPRKB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83407
TM6SF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09518
Photoreceptor distal connecting cilium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.759
GSE142019,GSE142021_1_v_3_ythdf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE246461,GSE246463_5_v_2_mecp2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DENND10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.95531
GSE65617_5_v_3_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GPN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07985
GSE60217_1_v_2_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8905236-mmc2.xlsx-Table_S10-Table_S10_Differentially_regulated_genes_in_SPI1_high_vs_low_group_in_CGGA_GBM_dataset_SPI1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF582	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.6553
HNF1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8372
LDAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75678
GTF2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68862
Neuron_Dorsal root ganglia_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.8756
NPLOC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3894
RORA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.8589
GSE149264,GSE149267_9_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WRAP73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49276
GSE145915_0_v_1_pcm1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6178
GSE145323,GSE145324_9_v_2_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE173911,GSE173917_0_v_1_morc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.1387
GSE175787_5_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UROD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23919
ENC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04603
496100407_FWM_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.00204
GSE135350_3_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain_CT2_Splat 358	HuBMAP ASCT+B Annotations	1.0	null
GSE62292,GSE62295_2_v_0_col4a3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FBXW2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56055
BMPR1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.65438
Pons	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.781
Subthalamic nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.622
PRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.89215
GNA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11769
increased vertical activity	IMPC Knockout Mouse Phenotypes	1.0	null
GSE175787_13_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
CPSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92679
LIMK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08796
PMC11522423-41598_2024_76982_MOESM1_ESM.pdf-28-ENSG00000177599_ZNF491	Rummagene Transcription Factor Associations 2026	1.0	null
AMIGO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.00542
Human - Tonsil - L2 - SCM CD8 T	HuBMAP Azimuth Cell Type Annotations	1.0	null
Stat6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.1641
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199034_1_v_0_pirfenidone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1225
CTTN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.33109
Cell body fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.146
GFI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.4531
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6259
C1D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04606
CDK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.97479
PCED1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28115
l23	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.135
GSE199606_2_v_7_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Cognitive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.279
Vibrissa	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.98
FAM168A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73119
NCBP2AS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35344
SOCS4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.561
Occipital pole	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.501
ATP5MG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15039
NPIPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39235
SRF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.5289
RELT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63083
EID2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.66236
Excitatory synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.265
WBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41251
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_EA-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
RIPPLY3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.06532
Visual cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.273
HOOK3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.78071
GSE138001_0_v_4_rorb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11668092-12884_2024_7077_MOESM1_ESM.xlsx-Table_S2-Table_S2_Full_result_of_MR_estimates_for_the_association_between_druggable_genes_and_HG_based_on_Finngen_study_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SPSB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28176
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.75459
FBXO30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05736
ZNF792	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13229
PMC12712253-12672_2025_4014_MOESM1_ESM.xlsx-Table_S4-Table_S4_The_result_of_MR_analysis_for_PC_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Up_bins-Up_bins_gaining_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF254	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48574
FOXP3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7691
TRIP10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79669
TEP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.24237
USP31	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33971
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.31295
NEUROG1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.928
NR4A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.9378
GSE81803,GSE81912_2_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Heel bone mineral density x serum urate levels interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.2
GSE123943_4_v_3_sox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
BNIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07189
DDX43	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.89325
Cerebral cortex	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PPARA::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.454
Satellite glial cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.015
C-2 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.11
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.3939
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nr1h4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.5771
Kidney	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Symmetric synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.543
Spleen	GTEx Tissue Gene Expression Profiles 2023	1.0	2.29187
TRIM59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40912
GSE224096_1_v_0_cocaine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pars tuberalis	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.794
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.275
MRPL36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.04811
COA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23797
FAAP24	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.92357
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.71114
ERF::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.9023
FMNL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.69526
PMC8046804-41467_2021_22478_MOESM11_ESM.xlsx-Del_AA-TCGA-Unnamed_16_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHTF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77221
E2F7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.9622
Brain_CT2_Splat 358	HuBMAP ASCT+B Augmented with RNA-seq Coexpression	1.0	null
MEF2D	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.1016
GSE221077_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE100528_1_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FAM210A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.48161
PMC8528285-pbio.3001085.s010.xlsx-Fig_8C-MLX_3T3_MLX	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF214	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3324
GSE174586_0_v_1_slc4a11_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UTP23	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11912
DBT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10648
GPR20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01441
Temporal lobe	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
POLR2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.74357
AP5M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.82543
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-4_E2F8-Gene_E2F8	Rummagene Transcription Factor Associations 2026	1.0	null
Human - Motor Cortex - Cluster - RORB+ LNX2+ Layer 3-5 glutamatergic neuron	HuBMAP Azimuth Cell Type Annotations	1.0	null
Parasympathetic nervous system	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.785
PAX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.3023
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	60.239
RUSF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14046
SMCHD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34969
Depressive disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.082
Mouse - Motor Cortex - Cluster - Layer 2-3 glutamatergic neuron, intratelencephalon-projecting_3	HuBMAP Azimuth Cell Type Annotations	1.0	null
GSE162688_1_v_2_pink1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234340_12_v_2_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COX19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36133
PMC10011543-41419_2023_5707_MOESM4_ESM.xlsx-genes_with_unique_SNP-F5-Pneo-r__CIC-2n_h-r_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
TCF7L2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.218
TBC1D10A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.68925
SPATA25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45398
CHPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11496
Femur bone mineral density x serum urate levels interaction	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.852288
Forebrain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Hypothalamus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.335
RBBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.91647
CRTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12979
GSE175787_5_v_2_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Chimp_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NKX6-3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2533
ABI1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.34139
PTRH2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16108
SSTR3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.1235
GSE135350_2_v_7_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
RPRD1B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33586
GSE114883_0_v_2_romidepsin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE196699_4_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
DCAF12L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05593
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_DBP_ALL-GENE_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
POU3F3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9903
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07651
SUPT5H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.1279
MSL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51117
SLC9A6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.73
GSE174498,GSE174500_2_v_7_asparaginase_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SEZ6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19089
RILPL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.25533
SLU7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.26784
GSE234289_5_v_2_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE165122_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TMEM218	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.15671
Retrosplenial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.272
MRRF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2049
VCX3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42709
RBM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34099
GSE143830_0_v_1_trex1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HES5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34792
PMC3507642-1471-2164-13-355-S4.xlsx-direct_AR-activation_Cmpd30-DN-HUGO_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Human - Motor Cortex - Cross-Species Cluster - Sncg+ GABAergic neuron_4	HuBMAP Azimuth Cell Type Annotations	1.0	null
TRDMT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36396
Auditory cortex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.926
Presynaptic endocytic zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.973
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_attenuatedResponse-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
decreased grip strength	IMPC Knockout Mouse Phenotypes	1.0	null
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE65617_0_v_4_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EIF2D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0116
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RNF20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03846
Rfx6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.6982
TCEAL5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.23092
SOX12	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.6485
PSMA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44909
FOXK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.73934
Myenteric plexus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.562
AVL9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.37888
GSE240027,GSE240030_5_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36101
496100596_FWM_dementia_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.56621
GSE122990,GSE123061_0_v_1_urod_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Neurofilament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.336
Internal plexiform layer	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.557
GSE73381,GSE73382_0_v_1_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Rarg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	48.7658
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.9571
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
SLC25A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.4549
GSE168458_1_v_3_disulfiram_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8074
PMC7997806-41397_2020_194_MOESM2_ESM.xlsx-MAGMA_GENE_MAP_AA-SYMBOL_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.1147
beta-N-acetylhexosaminidase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.924
TBC1D10B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6951
CNEP1R1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.6736
Urinary system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Unnamed_7_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
Skeletal muscle cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.972
GSE135350_3_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DRAM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63368
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
PARP12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.4283
OPA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.50113
CA14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.86596
H3-4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10558
Lissencephaly 9 with complex brainstem malformation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	2.297
GSE135350_2_v_4_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC11118997-12931_2024_2848_MOESM1_ESM.xlsx-Table_S6-Table_S6_The_result_of_MR_analysis_and_sensitivity_analysis_for_DLco_decline_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.9381
NR4A2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0951
GON7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.44256
INPP5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05302
Psychotic disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.041
PAX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	40.9205
NAV2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64256
Cerebral hemisphere	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Basal dendrite	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.042
RIPPLY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62732
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE137177_1_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MARCHF5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52257
PCYOX1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.83569
C-fiber	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.432
AGAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36987
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.1372
PMC8020666-pnas.2015855118.sd11.xlsx-LPS_strongerResponse-Chimp_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GPRC5C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11944
RARA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	62.5219
PMC12917211-Table1.xlsx-Table_S13-Table_S13_Gene-level_perturbation_statistics_from_the_virtual_KLF5_knockout_model_in_malignant_ductal_cells_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
S1PR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35711
SERPINE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.56715
GSE206870,GSE206872_1_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POMGNT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.89763
Integrin alpha6-beta1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.717
XPR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15808
Extracellular region	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5219
GSE230656_0_v_1_gsdmd_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Schizophrenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.046
GSE210580_3_v_11_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NDUFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48778
FKBP9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.01459
C20orf96	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.51809
SOX9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21962
G protein-coupled GABA receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.775
CCNI	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58838
TRAPPC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52696
Cerebral peduncle	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.078
Dmrt1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	18.7474
496100317_FWM_no dementia_no TBI_81_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.52881
PMC9084694-RMB2-21-e12464-s005.xlsx-GV_MI_MII_GV-up-GeneName_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Significant_DE_genes_in_AKT1_vs_KLF4_meningiomas_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
MSANTD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07584
GSE108675_3_v_0_slc1a4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Pervasive developmental disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.238
Excretory gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
chp212	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.583
LTC4S	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11108
GSE60217_1_v_7_inosine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PLCD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00665
PSMD5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19388
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.3441
Zona incerta	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.02
NDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54628
Piriform area	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.08
ZBTB3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05903
PFKFB4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.53531
BANP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2063
TRIM17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.1388
Foxj3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.0194
AMOT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.68392
CDC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.57379
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.293
PMC12297505-41598_2025_11704_MOESM4_ESM.xlsx-table_s4_veen-GSE16011_AND_TCGA-GBMLGG_NOT_Human_kinases_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
ANKRD54	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36554
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.4195
GSE206226_2_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Mood disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.116
RXRA::VDR	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3
PMC7176284-pcbi.1007753.s008.xlsx-2_MYCN-NA_NBL_Multimodal_Genes-gene_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131887_1_v_0_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Diencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.335
Longevity	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.552288
Mouse - Motor Cortex - Cluster - Layer 5 glutamatergic neuron, extratelencephalon-projecting_4	HuBMAP Azimuth Cell Type Annotations	1.0	null
REXO2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04974
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
URB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.19505
PMC8528285-pbio.3001085.s010.xlsx-Fig_S8C-GENE_LIST_UPLOADED_TO_ENRICHR_MAX_KO_3T3_DE_NOVO_69_GENES_MAX	Rummagene Transcription Factor Associations 2026	1.0	null
dystrophin-associated glycoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.209
GSE210580_4_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.013
GALNT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06395
GEMIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02188
GSE211983_0_v_3_nicotine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
generation of neurons	GO Biological Process Annotations 2025	1.0	null
MPST	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28149
Autism spectrum disorder	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.223
XPO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.72455
ZGRF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.70889
PRDX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30737
GSE201217_2_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARMC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07746
SPR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.71201
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of neural precursor cell proliferation	GO Biological Process Annotations 2025	1.0	null
FOXI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.6234
Isl1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.1166
JMJD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10487
RPLP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.24216
KRCC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63851
Mouse - Motor Cortex - Cluster - Layer 2-3 glutamatergic neuron, intratelencephalon-projecting_2	HuBMAP Azimuth Cell Type Annotations	1.0	null
TMTC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07501
HDAC6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08096
GSE175683_3_v_2_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ETV2::HOXB13	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.6944
Medial geniculate nucleus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.746
PMC10016690-Table_3.xlsx-AKT1_vs_KLF4_deg_all-Unnamed_4_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE85874_4_v_1_kdm5c_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
mRNA cleavage and polyadenylation specificity factor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.846
Parasympathetic ganglion	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.992
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE161295_4_v_1_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NDUFB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.75053
HNF1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.1279
MMRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09403
Occipital lobe	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.156
496100277_FWM_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.27068
Olfactory tract	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.837
Colonic sensory neuron_Dorsal root ganglia_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
TTC30A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.27043
SPHK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.77761
PAT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.577
HOXC10	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3093
Dystroglycan complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.336
PMC9618568-41467_2022_34255_MOESM4_ESM.xlsx-TAL1-Unnamed_0_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
HO-8910 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.662
PMC6938365-pone.0226733.s019.txt--MAFF_MAFF	Rummagene Transcription Factor Associations 2026	1.0	null
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.7676
ZNF253	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.75306