association	dataset	threshold value	standardized value
SG in caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.950022
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242674
Proventriculus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.59
PMC8384902-mmc6.xlsx-DEG_3TF_KD_unique-GeneSymbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE195503_3_v_0_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7317-01A-31R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
V, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.894182
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40122
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JF-62-LU77_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211384
HCC1187	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.674347
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_430_KD_FOXM1_SRP371675	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.62721
PMC6684323-NIHMS1532201-supplement-Table_S6.xlsx-LPS-Sup_Table_6C_Delta_PVE_among_PopDE_genes_LPS_PopDE_FDR_0_2_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
7516_RPS27A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.550036
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203-2004(H5N1)_7Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.72232
Brain - Hippocampus	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.20666
Leukemia, Chronic T-Cell_T lymphocyte_GSE5788	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.6748
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.94097
BA-77-US35_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.361684
U251	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.9932
BB-87-SF89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231554
PMC7455079-jciinsight-5-140380-s227.xlsx-Supp_Table_8-ILL1_T_Cells_FOXP3_FOXP3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Creb3l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7276
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18593951-TableS2	GeneSigDB Published Gene Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
I-II	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.89553
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20113
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPD_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK4	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-A49C-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66526269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09813
BRD-K62698674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02425
CC-61-HH09_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.704151
NR1H3	ChEA Transcription Factor Targets	1.0	null
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982128
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSKMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06483
hsa-miR-612	TargetScan Predicted Conserved microRNA Targets	1.0	0.23348
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DENND10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03763
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25456
GSE210667_1_v_0_rfx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63969
TCF3-18467660-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Metyrapone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.43
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DAN-G	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.58205
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45832
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_18Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.91082
SOX2-22085726-NPCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE216326_2_v_0_sulodexide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.778546
UACC812	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.997751
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.21346
GTEX-XQ8I-1726-SM-4BOQB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13145
GTEX-OIZG-0226-SM-2TC5L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877392
GSE111102,GSE111105_3_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K30589514	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51809
NANOG-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE147662_3_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
SJCRH30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08662
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMT5B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.7037
GSE159678_4_v_7_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139966_4_v_2_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P78B-1326-SM-3P611	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862922
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927985
496100431_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.1897
BRD-K49050984	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41948
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
IV, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25623
Cochlear nucleus, subpedunclular granular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03279
Hyperplasia	CTD Gene-Disease Associations	1.0	1.1198
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
FA-02-RV60_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.216053
HNF4A	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051079
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.27221
primary somatosensory cortex (area S1, areas 3,1,2)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.858872
GSE159049_1_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_2736_KD_Smyca_SRP330233	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.72989
ELF1	ENCODE Transcription Factor Targets	1.0	null
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869312
Brain Lower Grade Glioma_LGG_TCGA-HT-7691-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207863_0_v_1_hdac5_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-652-ENSG00000196152_ZNF79	Rummagene Transcription Factor Associations 2026	1.0	null
solitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.0182
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-QV31-0726-SM-3GAEG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874152
BRD-K89142472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07626
Epididymis	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35386
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_2day-MOI-10^4_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.83355
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
UBE2D3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0022
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946888
Anterior cingulate area, ventral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02803
VZ in midcingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00102
FOXP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1271
posterior (caudal) superior temporal cortex (area 22c)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.39224
MONOMAC1	CCLE Cell Line Gene Expression Profiles	1.0	1.93836
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.85046
GSE196699_2_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TIE1_knockdown_107_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-2.2929
GSE236003_0_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.51405
GSE229468,GSE229471_2_v_3_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
CDK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27221
PMC12478272-mmc1.xlsx-Table_S7-Supplementary_Table_7_Proteome-wide_MR_and_sensitivity_analysis_results_using_the_brain_pQTL_dataset_from_Wingo_et_al_1_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
SEC23IP	Pathway Commons Protein-Protein Interactions	1.0	null
GSE160246_0_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196699_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
glis2_17618285_kidney_lof_mouse_gpl2897_gds2817	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.462813
2622_EMG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.872313
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08603
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4864-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75164441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18097
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.885246
FOXS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5053
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CXCR7_Deficiency_GDS3183_604_mouse_Neonatal semilunar valves	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NCI-H2171	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.920669
miR-142-3p_OE_GSE28456_470_human_Raji cells (B lymphocytes)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE149903_3_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A95442017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19424
Primary somatosensory area, barrel field, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18823
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30853940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2113
BRD-A90462498	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3658
GSE147210_2_v_5_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATF3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23168
KLF4-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_10310_KO_3110043O21Rik_ERP013119	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.4852
Lung squamous cell carcinoma_LUSC_TCGA-77-8153-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6883-01A-31R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Prostate adenocarcinoma_PRAD_TCGA-HC-8213-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K59356638	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23021
PMC3428949-supp_jem.20120910_JEM_20120910_sm.pdf-5-BACH2_BACH2	Rummagene Transcription Factor Associations 2026	1.0	null
Brain - Spinal cord (cervical c-1)	GTEx Tissue Gene Expression Profiles 2023	1.0	1.54956
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.919059
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146156_1_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BHLHE40_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203485_1_v_0_zdhhc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NE-94-VE83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239842
MAX_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE183413_0_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r8 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22738
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27042
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE120415,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-1626-SM-2YUN3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832889
GSE185881,GSE185884_2_v_3_ctcf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.84259
V	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.859285
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WHSE-0926-SM-3NMBS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26889
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1395	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.853599
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR4	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.37501
NACC1	ChEA Transcription Factor Targets	1.0	null
HELA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52797
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20766
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE149359_3_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_Fetal Lung	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PANC0213	CCLE Cell Line Gene CNV Profiles	1.0	1.43761
BRD-K59099886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.36283
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4449	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.960782
BRD-A64374397	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52423
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7312_RIOK2_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.14138
SNU620	CCLE Cell Line Gene CNV Profiles	1.0	1.38107
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.930054
BD-18-MM33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.271374
mantle zone of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05785
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH446	CCLE Cell Line Gene Expression Profiles	-1.0	-2.11255
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25- Th Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dorsal motor nucleus of the vagus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.881693
GSE106170_1_v_0_nap1l3_human	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.947366
17665260-Table2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0834
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.347
USF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me2_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE165548_2_v_5_gemcitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T5JC-2126-SM-32PMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3035
BRD-K51050934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27364
PMC9753996-jci-132-160767-s182.xlsx-EBF1_associated-A1BG_EBF1	Rummagene Transcription Factor Associations 2026	1.0	null
RARB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0139
rpmi8226	HPA Cell Line Gene Expression Profiles	1.0	1.22193
HCC1011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24605
Pamidronic acid	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.34
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 255.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.2634
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18895
GRACILE syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.157
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8036
hsa-miR-370	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.58469
BRD-K51707293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62879
cerebellar cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.836793
CTCFL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	42.7533
GTEX-OOBJ-2626-SM-2I3F6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.77945
Prostate adenocarcinoma_PRAD_TCGA-KK-A8IL-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-S7SF-2026-SM-3K2AS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18128
GSE202434,GSE202438_3_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Central amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40891
SNU349	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45741
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.747781
CA4 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.42657
BRD-K64531863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36655
r9 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19091
H3K36me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19091
18537972-TableS2	GeneSigDB Published Gene Signatures	1.0	null
BRD-K57226763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03394
intermediate stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.876
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4203
A172	DepMap CRISPR Gene Dependency	1.0	6.36896
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24747
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain - Cerebellar Hemisphere	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.902117
orbital frontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.14825
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0826-SM-4B65O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55818
Primary somatosensory area, barrel field, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11443
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
basolateral nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.82742
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111385_2_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.56555
superficial stratum of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76754
NUGC3	CCLE Cell Line Gene CNV Profiles	1.0	1.47879
GSE158834_1_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HC-86-IA49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220539
ZNF384_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131798,GSE131804_5_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDT8-2926-SM-32PKC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00509
CAPAN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.02473
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100463_FWM_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.08145
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041302
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07747
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41321
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7804_KO_Ythdc1_SRP065329	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BRD-K78656517	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19393
BE-45-UU35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288093
GTEX-S341-0226-SM-2XCAX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.872977
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
JUN_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KALS-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.0475
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8043-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-XN-A8T3-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RN64-0626-SM-2TC5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28757
NR1H3-23393188-ATHEROSCLEROTIC-FOAM-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PC-87-OG75_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.315227
organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE148695,GSE167281_0_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF395	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.74785
KDM4A	ENCODE Transcription Factor Targets	1.0	null
imatinib_homo sapiens_gpl96_gds3048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33914
BRD-K83190598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08664
r10 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30365
Perturb_2890_KO_Mecp2_SRP154883	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.81947
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36032
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07403
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.495607
GTEX-VUSG-1226-SM-4KKZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936148
GTEX-PLZ4-1226-SM-2I5FE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978883
stomach	HPA Tissue Protein Expression Profiles	-1.0	-0.845141
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22606370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18667
GTEX-Q2AG-0826-SM-2HMKF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.61389
TET1-21451524-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19026
ZFP281-18757296-E14-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K00081911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33872
XD-03-FM54_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251125
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12863
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IL-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K67979704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93444
GTEX-XXEK-0326-SM-4BRVV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03873
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7229-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K89325755	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04395
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-PX3G-2626-SM-2I3EG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50354
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3657	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31128
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-8161-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-665	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K81175414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19194
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204936
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00986
CORL24	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40195
icSARS CoV_12Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-0.970381
GSE216540_10_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1599	CCLE Cell Line Gene CNV Profiles	1.0	1.42404
GTEX-SNMC-1226-SM-2XCFP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06014
TE8	CCLE Cell Line Gene Expression Profiles	1.0	1.74435
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r10 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2574
Perturb_1386_Mut_Chek1_SRP299085	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.4558
PAAF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19186
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217873_1_v_0_nusap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
protein transport	GO Biological Process Annotations 2023	1.0	null
TCF3-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Piriform-amygdalar area, polymorph layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21174
GSE235596_0_v_1_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ChIP_H3K36me3_18692474_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.851408
GSE158834_2_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-92-8065-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HOXD3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.0871
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146982_4_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9307901-mmc2.xlsx-S5-GATA6-AS1_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE125157_1_v_0_piceatannol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hydrochlorothiazide-1987	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-T5JC-0011-R4A-SM-32PLT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39011
VIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.838082
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nfe2l2_18059474_liver_lof_mouse_gpl1261_gds3406	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.0507
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5129
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE167218_1_v_0_hoxd12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE198165,GSE198166_6_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HOS	GDSC Cell Line Gene Expression Profiles	1.0	1.44888
RELA	JASPAR Predicted Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4727-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A3DL-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AA-50-FY68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314592
parolfactory gyri, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.951712
GSE242199_9_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.973899
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO 829	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22273
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE145311_1_v_3_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K01278504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03612
r8 part of lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98496
L1236	CCLE Cell Line Gene Expression Profiles	1.0	1.9134
GABPA_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.504451
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.12841
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3144-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
PANC0403	CCLE Cell Line Gene Expression Profiles	-1.0	-1.7333
BRD-A20018680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73631
SK-MEL-28 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.879
GSE223008_6_v_3_calhm6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POU5F1-18700969-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE207282_1_v_0_polydatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
7424_RPAP3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.556252
SKMEL24	CCLE Cell Line Gene CNV Profiles	-1.0	-1.39605
CAPAN-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.88224
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54769228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30491
GSE234514,GSE234516_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43391
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34432
BRD-K25408656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14008
RARG	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6894
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA3	ENCODE Transcription Factor Targets	1.0	null
COQ7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01509
POLK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22361
GTEX-XPVG-0726-SM-4B658	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.866316
NCIH28	DepMap CRISPR Gene Dependency	1.0	3.42883
C10	DepMap CRISPR Gene Dependency	1.0	2.76897
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JW-1226-SM-3GACY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05549
BRD-K21789048	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36394
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-16	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.00352
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.490472
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
red nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.83235
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE198165,GSE198166_6_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128730_0_v_5_neratinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE200673,GSE200691_2_v_4_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120413,GSE120447_0_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE135030_3_v_6_fludarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSB-1626-SM-3LK6J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951061
GTEX-SUCS-0226-SM-32PLQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00272
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02877
S0-EE-YEKU_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.25671
MB-32-LQ97_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.368017
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84215
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
BRD-K94845132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08296
RH18	CCLE Cell Line Gene CNV Profiles	-1.0	-1.58739
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_D1_vs_D10-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11426526-ppat.1012555.s011.xlsx-DEG_MDDC_Jurkat_LPS_vs_MDDC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.833374
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fenspiride-2106	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.845141
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.51756
E2F4_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K64823749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60271
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K10160311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84871
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K96057608	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29652
BRD-K84060528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49178
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Uvula (IX), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16298
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NRF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.09818
BRD-A89846380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.25338
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NHM cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.407
Head and Neck squamous cell carcinoma_HNSC_TCGA-UP-A6WW-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE110440_2_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inner SZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.5778
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU61_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.00091
H3K79me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BHLHE40_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIRT6	ENCODE Transcription Factor Targets	1.0	null
SRF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF4	ChEA Transcription Factor Targets	1.0	null
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19792
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K04848570	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61431
fat pad	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.599675
Parasolitary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10683
Adrenocortical carcinoma_ACC_TCGA-OR-A5JE-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL2	ENCODE Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.846057
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RXRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	48.6024
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.892461
CHD7	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Z-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QLQ7-1726-SM-2S1QQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00011
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE239844_8_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCIH2030	CCLE Cell Line Gene Expression Profiles	-1.0	-1.83223
UCSD-242L	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42096
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TMA7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12858
RH41	CCLE Cell Line Gene Expression Profiles	1.0	1.66733
NELFA-20434984-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K16933266	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83526
respiratory system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K35897342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25411
nb4	HPA Cell Line Gene Expression Profiles	-1.0	-1.19083
BE-27-RQ61_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.524736
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE165704_0_v_1_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12355
PFEIFFER	CCLE Cell Line Gene Expression Profiles	-1.0	-1.62214
BRD-K35383890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83405
GB-73-QS80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21589
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_11_ZZZ3_ChIP-seq_in_shZZZ3-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05494
Breast_Myoepithelial_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.17096
BRD-K52423731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15242
BAIAP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00584
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5985-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12260_KD_IGF2BP2_SRP334258	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.066
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33257
BRD-K30065842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02619
GTEX-OXRP-2326-SM-2S1NL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852944
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
TEX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43883
BRD-K54024474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28287
GSE155972_0_v_1_setdb1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32662
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K88504000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.77634
BRD-K38350115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31834
GSE111247_2_v_5_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BE-27-RQ61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.544285
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11203
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
r10 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23744
BRD-K14216093	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1698
FOXA1	ENCODE Transcription Factor Targets	1.0	null
QB-99-OU03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.450319
BRD-K69082321	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33582
BRD-K11905754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04075
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0826-SM-2TC5M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.95634
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08613
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMC4-20622854-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K79334072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15729
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
GTEX-S33H-1826-SM-4AD65	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52281
mantle zone of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42507
NANOG-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SIN3A_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gonad	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K50685439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12533
Pharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TCF3-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.881209
RS 67333	DeepCoverMOA Drug Mechanisms of Action	1.0	0.35
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30519
SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.955736
SNU-387	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82737
SNU-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67938
spironolactone-6255	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K92440102	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96513
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03284
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3358-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mantle zone of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76754
Nasopharynx	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Slow twitch muscle fiber	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.679
GSE190235_0_v_2_foxo3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
U266B1	CCLE Cell Line Gene CNV Profiles	1.0	1.46683
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_1_ZZZ3_ChIP-seq_peaks-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN013_HEPG2_24H:C19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.00105
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.092
BRD-K09376533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46995
MECOM-23826213-KASUMI-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_15017_KI_Stat6_SRP374172	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.16114
PAX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.9462
Prostate adenocarcinoma_PRAD_TCGA-EJ-5514-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
SRF-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Respiratory allergy	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.29
GSE81803,GSE81912_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE196671_5_v_0_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04368
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE136622_6_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MZ in dorsomedial parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.42357
H3K79me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154577_6_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
layer V of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51246
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186440,GSE186443_2_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
NC-27-AD53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.797433
17234769-TableS2a	GeneSigDB Published Gene Signatures	1.0	null
Nr5a1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	43.5931
GTEX-S3XE-0526-SM-4AD4G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827764
FOSL2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22244754	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19536
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TADA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.58311
BRD-K39489370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.5578
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35429158	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20939
AC-36-SY22_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218499
GTEX-X4XX-0011-R1B-SM-3P622	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03772
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78458
Brain Lower Grade Glioma_LGG_TCGA-DU-A7TD-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.309991
Elf5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.9516
Rectum adenocarcinoma_READ_TCGA-DC-4749-01A-01R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A2EF-01A-12R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NUGC2	CCLE Cell Line Gene CNV Profiles	1.0	1.38384
Immune system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.29
GSE154577_7_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SIGLEC10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03965
inner SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03066
GTEX-XXEK-1126-SM-4BRUX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.76569
7505_RPS16_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.888398
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
positive regulation of GTPase activity	GO Biological Process Annotations 2023	1.0	null
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GATA2_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4666-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17769
GSE140322_3_v_2_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFG7-2226-SM-3GIKP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.998762
(S)-(-)-Pindolol	DeepCoverMOA Drug Mechanisms of Action	1.0	0.26
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7008-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11917
BRD-K32925057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26715
GSE195582_0_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HL60	CCLE Cell Line Gene Expression Profiles	1.0	2.5401
orbital frontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55304
H3K4me3_Breast vHMEC	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72Z-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_13_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HMB-Val-Ser-Leu-VE	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.25
MON	DepMap CRISPR Gene Dependency	1.0	9.08885
hsa-miR-548aj	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
retina	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.2859
Prostate adenocarcinoma_PRAD_TCGA-EJ-8469-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K82539366	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07372
acemetacin-7442	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-QV44-0826-SM-2S1RG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59997
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	2.14196
BRD-K92022897	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38469
GSE150049_2_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FGFR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2883
GSE129287_0_v_1_cd200_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00837
ovary_6a	HPA Tissue Sample Gene Expression Profiles	1.0	0.898736
r9 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41392
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
basomedial nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.20807
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29V-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.296
BRD-K51385533	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2333
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.830057
BRD-K69659917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01675
gata1_15895080_e12dot5_liver_megakaryocyte_lof_mouse_gpl1261_gds1316	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-1.19021
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S15-Table_S15_MR_resluts_of_brain_pQTL_and_small-vessel_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE169155_6_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33184
Blood plasma	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.167
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Rab-GTPase-TBC domain	InterPro Predicted Protein Domain Annotations	1.0	null
mantle zone of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30365
GSE156708_1_v_2_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.66808
enzyme regulator activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K21695872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12906
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65881
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
GTEX-OIZH-2626-SM-2HMJM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19115
COLO-668	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Sarcoma_SARC_TCGA-X6-A8C3-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CEBPB_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW954	DepMap CRISPR Gene Dependency	1.0	3.78927
MECOM	ChEA Transcription Factor Targets	1.0	null
ChIP_H3K9me3_19884255_mouseESC	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BE-38-UW72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242135
H3K9ac_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K77004285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20937
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
tuberomammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.833455
GSE136622_2_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFYA	ENCODE Transcription Factor Targets	1.0	null
HCC1599	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.905289
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.11797
primary auditory cortex (core)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.56078
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-1626-SM-48TZC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857637
Brain Lower Grade Glioma_LGG_TCGA-DU-A6S8-01A-12R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_TCF3_18467660	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
cerebellar cortex_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.06825
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.38435
A704	CCLE Cell Line Gene Expression Profiles	-1.0	-2.59351
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901034
JUND_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventral part of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06996
RCC10RGB	DepMap CRISPR Gene Dependency	1.0	2.15564
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28119
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A94W-01A-12R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00387
CAMA1_BREAST	CCLE Cell Line Proteomics	1.0	4.09891
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.04847
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.26987
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-FX-A3RE-01A-11R-A22K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5878-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC3610249-1471-2164-14-184-S4.xls-miR-331-3p_targets-NR2E3_NR2E3	Rummagene Transcription Factor Associations 2026	1.0	null
Esmolol	DeepCoverMOA Drug Mechanisms of Action	1.0	0.27
POU5F1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.569398
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96399
BRD-K72647169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74971
GTEX-NPJ7-2726-SM-2I3FT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23288
SR786	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80726
H3K79me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE201270,GSE201272_0_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nucleolus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10232
Brain - Substantia nigra	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.17083
Thorax	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ELK3_01_318	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60561
GTEX-WYBS-1926-SM-3NM8N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.860709
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5699-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K28467592	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26965
RPMI-7951	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.93206
GSE166944_3_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5444-01A-02R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
GSK3B_knockdown_158_GSE35351	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.88057
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE193258,GSE193259_5_v_12_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lower (caudal) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.978083
TK-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.9053
GSE202434,GSE202438_4_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NVL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08376
NANOG-21062744-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	1.0	1.29492
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169155_5_v_4_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE201270,GSE201272_5_v_3_mybl2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDVN-0826-SM-48TZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870618
CFPAC1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49809
GSE237426_0_v_1_eif4a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
positive regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
cerebellar cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40415
IGR1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46261
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041529
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2928-03A-01T-0740-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.565084
TSHZ1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.25739
GSE186810,GSE186813_7_v_0_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.939208
4805_MAP2K7_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.15669
GSE113329,GSE113335_2_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K54686062	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20347
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R3RS-0726-SM-3GIJR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.863072
GSE109530,GSE109531_1_v_3_hdac3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ursolic acid-7181	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52834
AA-58-FJ71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.396297
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22037
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33099
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00355
GTEX-T5JW-1326-SM-4DM5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34869
GSE190384,GSE190386_0_v_4_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_7679_KD_NBAS_SRP267245	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Lung adenocarcinoma_LUAD_TCGA-86-6851-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
GSE68155_3_v_2_gpr3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SARS-BatSRBD_48Hour_23935999_GSE47961	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.67173
HCT-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.97034
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XX-0926-SM-46MV7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28382
nuclear lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21786
CRCGN014_HEPG2_3H:M13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1209
Perturb_6640_KD_ZBP1_SRP298473	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.34801
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965819
OLIG2-29049317-MOUSE-SPINALCORD	ChEA Transcription Factor Targets 2022	1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48081
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KE39	DepMap CRISPR Gene Dependency	1.0	2.5112
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384	ENCODE Transcription Factor Targets	1.0	null
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.28231
BRD-K81801123	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32206
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:B04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08961
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ3S-2526-SM-4BOOG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34604
primary motor cortex (area M1, area 4)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17817
NCI-H446	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.58807
BRD-K63920153	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3299
GSE220668_0_v_1_ncapg_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2795
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3133	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
HOXC9	ChEA Transcription Factor Targets	1.0	null
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.35509
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869312
POLR2AphosphoS5_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GE-47-OO30_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.298723
8759_TBX5_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.69425
LHX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.372
ARPC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49395
BRD-K03286808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36352
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51697315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08944
adult retina	HPM Cell Type and Tissue Protein Expression Profiles	1.0	1.14787
ZNF263	ENCODE Transcription Factor Targets	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	0.944872
EP300_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-0626-SM-3DB8L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20222
BNC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.4201
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.06807
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SRF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYK_druginhibition_289_GSE43510	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.49921
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R53T-0226-SM-48FEH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927237
OCUG1	DepMap CRISPR Gene Dependency	1.0	2.40712
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE77108_6_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE110440_1_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.239
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAS	GDSC Cell Line Gene Expression Profiles	-1.0	-1.51708
EP300_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10286_KO_Ypel3_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.5848
SG in midinferior temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10284
GSE210101,GSE210114_2_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SIX5	ENCODE Transcription Factor Targets	1.0	null
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GTEX-PX3G-2426-SM-48TZZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02307
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.10167
SFRP5_KO_GDS4988_27_mouse_gonadal white adipose tissue HFD	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
perifornical nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.876081
BRD-K44908880	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78912
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-0008-SM-48TDU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.968881
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.940198
GTEX-S7SE-0726-SM-2XCD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4012
MAPK14_KO_GDS2693_535_mouse_liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.09007
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K59078001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.25976
EOMES	ChEA Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-Z4-A9VC-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22097
hsa-miR-4731-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.062888
BRD-K01754917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38928
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE136622_7_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Arntl	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.0996
Lateral reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19091
mantle zone of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68192
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50604
GSE199255,GSE199356_3_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BEN	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.46503
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.254093
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.903577
NRL	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0024
FOXM1	ENCODE Transcription Factor Targets	1.0	null
REST_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parolfactory gyri, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.37945
Lung squamous cell carcinoma_LUSC_TCGA-63-6202-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5585-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5709-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FB-66-UU47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.359621
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96131
ZNF93	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	170.949
GTEX-WHSE-3026-SM-3P5ZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22362
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RT-A6YC-01A-12R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-64-1676-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE210101,GSE210114_8_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.826931
NCI-H847	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.15682
outer SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13757
testis_7d	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00227
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S11-Table_S11_MR_resluts_of_brain_pQTL_and_any_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K85051145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80326
BRD-K34192219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04053
GTEX-SN8G-0326-SM-32PLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.225
A-Netherlands-602-2009(H1N1)_24Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.51628
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BICR 22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.48327
hsa-miR-4510	TargetScan Predicted Conserved microRNA Targets	1.0	0.03694
PMC5105166-ncomms13331-s5.xlsx-Sheet1-Supplementary_Data_4_Gene_expression_signature_of_MEF2D-rearranged_cases_stranded_data_only_MEF2D	Rummagene Transcription Factor Associations 2026	1.0	null
CRCGN009_HEPG2_24H:O19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.49256
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75616
GSE248045,GSE248046_6_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.915586
GSE71468,GSE76476_2_v_1_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.31341
adipocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.612958
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ERG-20517297-VCAP-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCI-H1373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.849299
Primary somatosensory area, barrel field	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22915
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7368-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K94518115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6694
intermediate stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43391
NCI-H1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.864439
Primary somatosensory area, barrel field, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13981
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185519_3_v_2_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_Targetome-Genes_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K76803075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13363
PMC8709578-elife-69843-supp4.xlsx-HSF1_ChIP-seq_peaks-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
karpas707	HPA Cell Line Gene Expression Profiles	-1.0	-2.20784
hsa-miR-26b	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72521
NR3C1	ENCODE Transcription Factor Targets	1.0	null
GTEX-RWSA-1126-SM-2XCAZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33983
TBK1.DF	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48081
CEBPB_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me1_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
positive regulation of gtpase activity	GO Biological Process Annotations 2015	1.0	null
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.7241
A172	GDSC Cell Line Gene Expression Profiles	1.0	1.70014
hsa-miR-4652-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
lateral part of MPO	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17918
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MZ in midlateral extrastriate cortex (area 19)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.880688
Lung adenocarcinoma_LUAD_TCGA-86-8281-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A10417568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34716
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30607
LOUCY	CCLE Cell Line Gene CNV Profiles	-1.0	-2.44706
BRD-A71933035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07461
Perturb_3779_KD_NFYA_SRP041162	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.1785
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52115
BRD-K56618252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15546
SW480_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	2.13899
CCDC120	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.76423
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
inner SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.36
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42324
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CE-04-PX35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.406011
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleoside-triphosphatase regulator activity	GO Molecular Function Annotations 2015	1.0	null
BRD-K88395026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49296
BRD-K39761541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02676
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FGFR1_mutant_25_GDS4046	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.19003
r9 part of dorsal parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2574
MAFK_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rnf2_20805357_u2os_osteosarcoma_lof_human_gpl570_gse23035	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.622364
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.998935
IRX6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04998
nfe2l2_20133372_lung_lof_mouse_gpl1261_gds3622	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.291397
GSE140607_0_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NKX2-5-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-S32W-2326-SM-2XCAW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24894
BACH1	ENCODE Transcription Factor Targets	1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35041
Brain Lower Grade Glioma_LGG_TCGA-WY-A859-01A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-let-7b-5p	MiRTarBase microRNA Targets	1.0	null
VIIIA	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.875872
GSE217105_0_v_1_gemcitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.13269
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AD-16-HL96_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.263231
ZNF384_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06997
18691415-Table5d	GeneSigDB Published Gene Signatures	1.0	null
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30771
C-33-A	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.51241
GTEX-XOT4-0326-SM-4B66S	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918071
BRD-K29673910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74249
GSE214725_1_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE111247_2_v_3_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsal endopiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40196
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BV173	CCLE Cell Line Gene CNV Profiles	-1.0	-1.80139
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19218430-TableS3	GeneSigDB Published Gene Signatures	1.0	null
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
A-CA-04-2009(H1N1)_12Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.08594
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A0C8-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205976,GSE205978_2_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WFON-1726-SM-4LVMQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16468
BRD-K50247051	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09141
GSE203158_1_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CMK115	DepMap CRISPR Gene Dependency	1.0	4.10491
BRD-K55147629	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35153
GSE199204,GSE211619_4_v_7_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GB-98-IZ84_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210359
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.930024
r8 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06188
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K20895937	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26655
GSE154577_2_v_9_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-548am	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE144115_1_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RNF2	ENCODE Transcription Factor Targets	1.0	null
r9 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85606
COLO792	DepMap CRISPR Gene Dependency	1.0	4.56112
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.875418
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE160246_0_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IST-MES1	GDSC Cell Line Gene Expression Profiles	1.0	1.98162
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
SF295	COSMIC Cell Line Gene Mutation Profiles	1.0	null
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.53618
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3YS-01A-11R-A23N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196671_5_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE114992,GSE114993_7_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.912943
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Endocrine system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.032
primary visual cortex (striate cortex, area V1/17)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14906
heart	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-2.30903
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.23646
BICR18	CCLE Cell Line Gene CNV Profiles	1.0	3.27619
BRD-K45819372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56292
WholeBlood	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.829618
RPE1SS119	DepMap CRISPR Gene Dependency	1.0	2.50851
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5691-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE154577_2_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31491
intracellular organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
PMC5651844-41467_2017_1173_MOESM10_ESM.xlsx-ZZZ3_occupied_genes-Unnamed_9_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.891373
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Melanocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.592
AE-39-DG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.348867
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K54712090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34092
Central amygdalar nucleus, capsular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29437
GTEX-X8HC-0626-SM-4E3HQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05864
protein localization	GO Biological Process Annotations 2023	1.0	null
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-L4-A4E5-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S3XE-2026-SM-3K2B5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55888
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TK10	BioGPS Cell Line Gene Expression Profiles	1.0	0.839113
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.758497
BRD-K80577041	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00355
TCF3	ChEA Transcription Factor Targets	1.0	null
KYSE-30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE196699_7_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
skeletalmuscle	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.46087
GTEX-PLZ5-0326-SM-3P614	GTEx Tissue Sample Gene Expression Profiles	1.0	0.921507
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S14-Table_S14_MR_resluts_of_brain_pQTL_and_cardioembolic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
basolateral amygdaloid nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.60345
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997954
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10061014-Table5.XLSX-C_vs_L-Table_S5a_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q734-0726-SM-48TZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09746
Lung squamous cell carcinoma_LUSC_TCGA-39-5011-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WH7G-1626-SM-4LVMY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825334
Prostate adenocarcinoma_PRAD_TCGA-CH-5761-11A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE77108_0_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.46887
mammillary body, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.841759
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MLKL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30235
OAW-28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K73540839	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3437
NCI-H1693	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43404
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
orbital frontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.979298
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K56890200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10145
GTEX-XK95-0426-SM-4AT4R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12288
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
thyroid gland	HPA Tissue Gene Expression Profiles	1.0	1.09844
ZNF281	ChEA Transcription Factor Targets	1.0	null
MZ in posteroventral (inferior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.885723
Lung squamous cell carcinoma_LUSC_TCGA-92-8063-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BCLAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_2_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE132948,GSE132949_0_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAKI1	CCLE Cell Line Gene Expression Profiles	-1.0	-3.06707
GTEX-O5YT-1326-SM-3MJGR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988173
GTEX-RM2N-1926-SM-48FCU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92785
GSE198165,GSE198166_9_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Z8-0526-SM-4AD4T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858874
NUGC-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.905208
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YE-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07784
PANC 04.03	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.883685
GTEX-OXRK-0626-SM-2HMJ5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99138
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.43119
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TET1-21451524-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210842_3_v_1_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-2655-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22738
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A183-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184884_6_v_5_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GTEX-X4XX-0011-R4B-SM-46MWL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.888002
8-cell stage cell (Blastomere)_Embryo_Human	CellMarker Gene-Cell Type Associations	1.0	null
r9 part of ventral parvicellular reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33069
Brain Lower Grade Glioma_LGG_TCGA-FG-A4MY-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-3A-A9IR-01A-11R-A38C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08019
GSE231648_1_v_5_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CE-23-HP88_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2888
BRD-K79904333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71769
GTEX-WVLH-3026-SM-3MJG9	GTEx Tissue Sample Gene Expression Profiles	1.0	2.05847
A-CA-04-2009(H1N1)_36Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.85683
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02305
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OXRK-1326-SM-3NB1A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952142
NR3C1_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVUS-2826-SM-3GADB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35318
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.03086
2367_DPY30_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.620409
BRD-K30221348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43907
H4K20me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE220520_1_v_7_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.642446
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FW-A3TU-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nuc1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.543
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03079
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5894-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K95129711	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05349
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22738
A-CA-04-2009(H1N1)_7Hour_None_GSE37571	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.4753
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00719
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24487
537 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.31609
ZD 7288	DeepCoverMOA Drug Mechanisms of Action	1.0	0.33
KMBC2	DepMap CRISPR Gene Dependency	1.0	3.53421
BRD-K46376359	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43947
Perturb_10276_KO_31O21Rik_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.90539
NPIPA3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54891
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.29213
G118	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02278
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18121
GSE216394_2_v_0_pfkp_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4969-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE122425_1_v_0_nsun2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K65315551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02835
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1399
FOXF2	JASPAR Predicted Transcription Factor Targets	1.0	null
Hypothyroidism	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.032
ETS1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG-21062744-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
PPARG-20887899-3T3-L1 PREADIPOCYTE CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K20714346	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75099
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
hsa-miR-345	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
BRD-K88087295	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68063
BRD-K69054398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47138
GSE193588_1_v_0_pax3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16781
H3K36me3_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-NC-A5HO-01A-11R-A26W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QXCU-0626-SM-2TC69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.899194
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904558
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5697-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT3	ChEA Transcription Factor Targets	1.0	null
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.24036
CEBPB_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of organelle organization	GO Biological Process Annotations 2015	1.0	null
Nose disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.29
Brain Lower Grade Glioma_LGG_TCGA-DU-6397-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K10580455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7918
BRD-K75583553	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24191
FOXA2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular protein transport	GO Biological Process Annotations 2023	1.0	null
ARH77	DepMap CRISPR Gene Dependency	1.0	3.44289
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Rhinitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.29
GATD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51174
Lateral reticular nucleus, magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98496
BL8514 (CKAP2)	NURSA Protein Complexes	1.0	null
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18794137-SuppTable1e	GeneSigDB Published Gene Signatures	1.0	null
BRD-K88996011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22767
496100307_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.2706
kidney	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.15623
ZNF136	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.0878
Lung adenocarcinoma_LUAD_TCGA-55-6968-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SC-76-YF40_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281021
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15455
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.968114
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08134
BRD-K93044218	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71987
Perturb_9516_Mut_Sall4_ERP111723	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.92621
MECOM-23826213-KASUMI-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
TCF12_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral preoptic area, PO1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02643
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A822-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE112860_3_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:L10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14215
Basolateral amygdalar nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.77959
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17318
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
TCF3	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-3770-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GC-04-UF36_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.323865
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00046
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1915	CCLE Cell Line Gene CNV Profiles	-1.0	-2.19876
GSE195663_0_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U8T8-0008-SM-4DXSP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894017
GSE210655_1_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K62213484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78714
BRD-K11581306	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32887
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
TE-441-T	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.18262
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.89428
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SP-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K96627018	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95899
SOX2-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHUEM7	DepMap CRISPR Gene Dependency	1.0	6.33792
BRD-A50837272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13186
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HuP-T3	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.02849
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior amygdaloid area	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.982563
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.955783
Testis	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A7QW-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
UT7	CCLE Cell Line Gene Expression Profiles	1.0	1.46841
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.09751
GSE117042_1_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Npas2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.0968
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SMAD1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
6708_PPWD1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.508937
liver_c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.94229
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16411174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49651
Nodulus (X)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00387
POLR2AphosphoS5_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_10391_KD_BRDT_SRP273737	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
A-Vietnam-1203-2004(H5N1)_7Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.47596
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.968735
CRCGN011_HEPG2_24H:F03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.2065
Brain Lower Grade Glioma_LGG_TCGA-DU-A5TS-01A-11R-A28M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23197669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16962
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A677-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYOG	ENCODE Transcription Factor Targets	1.0	null
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.46932
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871387
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-19b-3p	MiRTarBase microRNA Targets	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_C91-PL_LPS_vs_DC_Jurkat-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
TC205	DepMap CRISPR Gene Dependency	1.0	4.02882
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K66754362	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12849
GSE128730_4_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
intermediate stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2574
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.09541
pc3	HPA Cell Line Gene Expression Profiles	1.0	1.09499
BRD-K56075657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25763
BRD-K78574327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44389
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.66413
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.37747
BRD-K72773309	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68579
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K42663371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25114
BRD-K22087390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20252
BRD-K99516890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06084
TUT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48255
TAL1_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18101567	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84032
SARS-CoV_0Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.62094
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01809
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BE-38-UW72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231946
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K03304013	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36672
BHLHE40_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-792	GDSC Cell Line Gene Expression Profiles	1.0	2.24064
Gracile nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39533
FLI1	ENCODE Transcription Factor Targets	1.0	null
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.61332
dorsolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.942771
CIAO2B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45926
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THAP1	ENCODE Transcription Factor Targets	1.0	null
GSE184356_3_v_0_tfam_human	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of gtpase activity	GO Biological Process Annotations 2015	1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.853401
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.92627
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZI-0626-SM-2XCEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893736
GTEX-X4EO-0326-SM-3P5YO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11757
NCIH1793	CCLE Cell Line Gene CNV Profiles	1.0	1.50809
Molting fluid	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.339
BCKDHA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23409
BRD-K02565327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45968
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.79551
NCIH1915	CCLE Cell Line Gene Expression Profiles	-1.0	-2.79237
Perturb_1606_KO_Tnfaip3_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.21472
GATA3-21878914-MCF-7-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC6855629-pone.0225186.s009.xlsx-Sheet1-DEGs_downregulated_in_HEK293_MEIS1_KO_MEIS1	Rummagene Transcription Factor Associations 2026	1.0	null
inner SZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20329
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K82863660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96815
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
HC-15-LT47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.411981
GSE81193_3_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75608
LGLL - Large granular lymphocytic leukemia_Peripheral blood mononuclear cell_GSE10631	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.57211
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TET1	ChEA Transcription Factor Targets	1.0	null
GSE173810_4_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-OXRP-0126-SM-3NB32	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958107
CRCGN008_HEPG2_24H:C20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.79148
PMC6962646-mmc2.xlsx-StemCell_Genesets_2018-ZNF257_ZNF257	Rummagene Transcription Factor Associations 2026	1.0	null
GSE207978_1_v_0_rai1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147876,GSE147877_2_v_7_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K48207398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33024
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESR2_01_229	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.61667
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5133
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14723547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40166
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
6581_POT1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.523624
OCIAML3	CCLE Cell Line Gene Expression Profiles	1.0	1.76531
Prostate adenocarcinoma_PRAD_TCGA-VP-A87B-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1871
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.28027
hsa-miR-548aa	TargetScan Predicted Conserved microRNA Targets	1.0	0.011888
HCC44_LUNG	CCLE Cell Line Proteomics	1.0	3.8752
ChIP_POU5F1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
PSMB6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23447
POU5F1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
USF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996807
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.95473
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-ZJ-A8QQ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
V, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09432
BRD-K59970200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00897
WB-82-EL69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.305923
Lung adenocarcinoma_LUAD_TCGA-55-8620-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999002
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE193588_3_v_2_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HOXC9-25013753-NEUROBLASTOMA-BE2-C-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20017
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K78961368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.65182
496100631_PCx_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.64093
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.8388
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-MES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999002
USF2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7832-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5690-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K34519170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27261
Brain Lower Grade Glioma_LGG_TCGA-HT-8019-01A-21R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79247
GSE131649_6_v_10_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OHPK-2626-SM-2HMK9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14346
GSE121198,GSE129782_1_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5367-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Oviduct	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
NCIH2030	CCLE Cell Line Gene CNV Profiles	-1.0	-1.61409
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE161864,GSE161866_4_v_3_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-G7-6795-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYBL2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2866
GTEX-Q734-1626-SM-48U1B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00995
GSE229344_1_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KE39	CCLE Cell Line Gene Expression Profiles	-1.0	-2.02836
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01963
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S32W-2126-SM-2XCB1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.973976
GTEX-SNMC-0008-SM-4DM5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01033
GTEX-T5JC-1726-SM-4DM6U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849579
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5677-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0946
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33086
SRF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCT-116	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.60457
GSE166944_0_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K61278167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40258
NUP62	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14058
KLF4-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE182854_2_v_3_sirt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE167224,GSE168147_1_v_5_hnrnpk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119694_1_v_0_lifr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4W-01A-12R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VUSG-1726-SM-4KKZL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96936
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
BRD-K06678077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3869
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.43868
Brain Lower Grade Glioma_LGG_TCGA-HT-7680-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.5279
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50976856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03832
BRD-K21470524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25808
GTEX-V955-0426-SM-3GAEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27541
G141	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16683
H3K4me1_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
mantle zone of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00387
hsa-miR-4739	TargetScan Predicted Conserved microRNA Targets	1.0	0.053794
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4667-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
NANOG-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE158834_10_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Breast_vHMEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.3936
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7CG-01A-11R-A32P-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
A-Netherlands-602-2009(H1N1)_18Hour_None_GSE40844	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.24314
BRD-K61182411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91596
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K97468369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25403
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.30018
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.87111
GTEX-X4XY-0826-SM-4E3JM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30372
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73E-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K86050213	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52596
GB-73-QS80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.388961
H4K5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A2LA-01A-11R-A18C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r7 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76754
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K40826084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29928
NANOG	ChEA Transcription Factor Targets	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PRDM11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10169
CYB561	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36366
intermediate stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.85606
periventricular stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2183
ERA-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
lateral nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75588
GTEX-WL46-0011-R1A-SM-3LK6M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17743
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A461-01A-41R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM1A	ENCODE Transcription Factor Targets	1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Gene_Name_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
NDUFB8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.68797
BRD-K95852319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12464
BRD-K42139332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8407
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YT-0926-SM-48TDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44981
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.933306
nifedipine-1856	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H4	DepMap CRISPR Gene Dependency	1.0	2.30245
GSE200673,GSE200691_2_v_0_hmga2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YD38	CCLE Cell Line Gene CNV Profiles	1.0	1.75253
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0126-SM-48TC6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825247
BRD-K28446462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03456
GTEX-OXRN-2626-SM-48TBX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882603
GSE210101,GSE210114_6_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE112860_3_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
EFO-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.87508
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	5.65402
CREM	ChEA Transcription Factor Targets	1.0	null
CTV1DM	DepMap CRISPR Gene Dependency	1.0	3.52809
MDS - Myelodysplastic syndrome_Bone marrow stem cell_GSE2779	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.41716
PMC4634137-ncomms9549-s7.xlsx-ZF_Hair_cell_data-Unnamed_1_CREBZF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12558
regulation of anatomical structure morphogenesis	GO Biological Process Annotations 2015	1.0	null
NTERA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.30096
CRCGN016_MCF10A.TP53.M_24H:D18	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.52943
SRF	ENCODE Transcription Factor Targets	1.0	null
PPP1R11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40579
ZFAND1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12539
GSE203308_15_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POU5F1	ChEA Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A3Y7-01A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6061
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.563
regulation of cellular component organization	GO Biological Process Annotations 2015	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K43414987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36729
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.852822
ZNF135	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	70.0749
GSE168171,GSE168173_0_v_1_ddx41_human	RummaGEO Gene Perturbation Signatures	-1.0	null
oculomotor nuclear complex, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.67351
BRD-K85527716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.83974
EN	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.16251
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.27774
TCF12	ENCODE Transcription Factor Targets	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.871067
H3K27ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5882-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K96440230	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14894
GTEX-U8XE-0926-SM-3DB8V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08552
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19646
NCI-H1915	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-3.00432
GATA2-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K72071403	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59552
medial preoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11118
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X8HC-0726-SM-46MWG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840515
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.37428
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE122067_3_v_0_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE140607_3_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K48689133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43122
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41178
pseudopelletierine-5828	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999002
SKRC31	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55022
EP300_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPM-2626-SM-33HC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.062
hsa-miR-3179	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K96981233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43875
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.844831
GSE198165,GSE198166_9_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.70379
Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.9688
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.883225
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
icSARA deltaORF6_7Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.94203
Perturb_10354_KD_MSI1_SRP288195	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.99483
GP5D	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27347
GSE227634,GSE228381_0_v_5_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Blood metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.9
GSE186810,GSE186813_7_v_5_furin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3127
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.903547
GSE228181_3_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXA2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5819
DICER1_KO_GDS4504_583_mouse_bone marrow granulocyte-macrophage progenitors	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K03383196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20588
RT-112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.873267
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.6333
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T5JC-1526-SM-4DM68	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11602
GTEX-U8XE-1526-SM-4E3HT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08005
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
STAT3-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00096
GTEX-R55C-0826-SM-48FCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835714
GSE158197_0_v_11_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6366065-13075_2019_1816_MOESM1_ESM.xlsx-DOD_Skin_imputed_log2_median_ce-Name_PIN1	Rummagene Transcription Factor Associations 2026	1.0	null
GABPA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99903568	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.75295
SP in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.863676
GSE202434,GSE202438_9_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE248045,GSE248046_0_v_1_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
MITF-21258399-MELANOMA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
SB-222200	DeepCoverMOA Drug Mechanisms of Action	1.0	0.22
GSE142210_4_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.994363
Perturb_7769_KD_Y14_DRP003223	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.8679
SIRT6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-1126-SM-3NMD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76016
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K73110675	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47059
GSE76771_2_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Parathyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Nanog	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.2595
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CA-48-SW47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203782
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Medullary reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.18556
FTC-133	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10928104-41419_2024_6576_MOESM4_ESM.xlsx-S14-E2F4_5_targets_E2F4	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K15609977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.13074
hippocampus (hippocampal formation)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.890914
gtpase activator activity	GO Molecular Function Annotations 2015	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07894
GTEX-T8EM-0526-SM-4DM64	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950491
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0726-SM-2TF4M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43308
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16657
DYNC1H1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44011
NELFE	ENCODE Transcription Factor Targets	1.0	null
GSE112761,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5651844-41467_2017_1173_MOESM10_ESM.xlsx-ZZZ3_occupied_genes-Supplementary_Data_7_ZZZ3_occupied_genes_and_overlaps_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZM-0126-SM-3DB8M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938857
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13533
BRD-K40697889	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30821
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-3026-SM-4B65M	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7312
GSE199644_3_v_2_palmitic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
rostral division of VL	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55646
GTEX-NFK9-0726-SM-2HMJW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46758
GTEX-QV31-0226-SM-447BO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0823
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral amygdaloid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46426
SkeletalMuscle	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.884208
Stat5a::Stat5b	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.6476
hsa-miR-346	TargetScan Predicted Conserved microRNA Targets	1.0	0.042355
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00199
BRD-K17602350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05197
4950_MED27_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.535945
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7II-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K87558616	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60677
SF767	CCLE Cell Line Gene CNV Profiles	1.0	1.36687
GSE156667_0_v_1_lrrc8a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EMC-BAC-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.25589
testis	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
3343_GFI1B_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.761795
BRD-K79020643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54843
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1573	CCLE Cell Line Gene Expression Profiles	-1.0	-1.52148
GSE157296,GSE157298_4_v_3_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of plasma membrane bounded cell projection assembly	GO Biological Process Annotations 2023	1.0	null
BRD-K98723391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38963
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_3Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.46077
NUS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.56068
PMC7934233-13059_2021_2293_MOESM8_ESM.xlsx-Fibroblast_HOXC6-gene_HOXC6	Rummagene Transcription Factor Associations 2026	1.0	null
thyroid_5b	HPA Tissue Sample Gene Expression Profiles	1.0	0.987448
CFPAC1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.54398
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13517
GSE184884_2_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NL4W-0011-R8a-SM-2I3G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0869
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R4B-SM-46MVH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.88457
Perturb_11193_KD_Zfp36l1_SRP289525	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.74435
GSE112765,GSE112767_1_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WM3211	DepMap CRISPR Gene Dependency	1.0	2.40208
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE190384,GSE190386_1_v_4_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TASK1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
D502MG	DepMap CRISPR Gene Dependency	1.0	2.25383
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.929534
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.930403
GSE127790_9_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NMT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47025
BRD-K24864035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36344
inner SZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.83025
HCV JFH-1_18Hour_20200238_GSE20948	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.63781
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferior olive, principal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.69692
GTEX-OIZH-0926-SM-48TBR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09571
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.98521
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_15855_KD_KDM3A_SRP270313	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
TAL1	ENCODE Transcription Factor Targets	1.0	null
A 803467	DeepCoverMOA Drug Mechanisms of Action	1.0	0.31
BRD-K44204252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13491
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S33H-1326-SM-4AD6A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15195
OCI-LY-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27783
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827621
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-0326-SM-48TDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.857965
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5696-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SOX2	ChEA Transcription Factor Targets	1.0	null
STAT1-19122651-HELAS3-HUMAN-CERVICALCANCER	ChEA Transcription Factor Targets 2022	1.0	null
CAL 27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.04281
BRD-K25016708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29868
ventrolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16624
GTEX-UPIC-1126-SM-4IHLO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43079
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CRYBG2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00492
PMC4905481-oncotarget-07-11397-s003.xlsx-Pinin_KD-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE158834_1_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199092_3_v_0_ddx5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE152441,GSE152442_6_v_5_folic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE134375_0_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE223008_4_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154767_4_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FLI1::DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.3435
BICR22	CCLE Cell Line Gene CNV Profiles	1.0	1.59427
BRD-K44797874	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46473
BRD-K51175229	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2022
GSE160246_9_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K76337122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00437
SNX30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42877
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
Nucleus of the solitary tract, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30365
Sarcoma_SARC_TCGA-X6-A8C6-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nasal cavity disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.29
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.595634
GSE154464_1_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U8XE-0426-SM-3DB91	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15176
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Infertility, Male	CTD Gene-Disease Associations	1.0	1.03678
GTEX-XPVG-0826-SM-4B654	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02044
EP300_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.13678
CRCGN017_MCF10A.WT.HP_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.03545
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.8808
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K14122415	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21705
ELK1::HOXA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4099
NCI-H28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00059
Anterolateral visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18993
KMRC2	DepMap CRISPR Gene Dependency	1.0	2.85996
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of cellular component biogenesis	GO Biological Process Annotations 2015	1.0	null
GTEX-U8XE-0226-SM-4E3J3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41295
496100390_PCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.37668
GTEX-Q2AH-0726-SM-2I3EA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977564
Acute Myeloid Leukemia_LAML_TCGA-AB-2885-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EIF4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1326
ATRFLOX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.54087
GTEX-VUSG-0426-SM-3GIKD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.870504
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Leukemia, Acute Megakaryocytic_Megakaryocyte_GSE2433	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.74916
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7927
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12524
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-WXYG-0226-SM-3NB2Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10137
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR0B1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11202
BRD-A98203122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29024
SMAD1	ChEA Transcription Factor Targets	1.0	null
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:K24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.23955
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.664138
lateral part of r9B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00387
Pancreas	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.937155
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52341452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24857
GSE226397_0_v_1_cystine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NANOG-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13593
brown adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.592444
BRD-K45569026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3725
SFRP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.60063
Microglial cell_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K91469267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42307
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.37812
STAT5A	ENCODE Transcription Factor Targets	1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5982-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
6453_PLK1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.503076
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38929
KPL-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.984896
BRD-K00078503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13151
placenta_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.849479
NCI-H2009	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.981121
Phagocytic cup	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.774
TCF7-22412390-EML-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
fallopian tube	HPA Tissue Gene Expression Profiles	1.0	1.04776
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GTEX-OOBJ-0926-SM-48TDO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02974
GTPase regulator activity	GO Molecular Function Annotations 2025	1.0	null
BA-38-XM43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21697
Lung adenocarcinoma_LUAD_TCGA-69-7979-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-421	TargetScan Predicted Conserved microRNA Targets	1.0	0.303626
SOX17	ChEA Transcription Factor Targets	1.0	null
REST_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ASXL1	ChEA Transcription Factor Targets	1.0	null
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F1-26619117-HEPATOCYTES-MOUSE-LIVER	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PVOW-0126-SM-2XCFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.964794
GSE98755,GSE98756_1_v_0_fbxl19_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-V955-0126-SM-4JBH5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991438
Sarcoma_SARC_TCGA-QQ-A5V2-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11844860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13311
Prostate adenocarcinoma_PRAD_TCGA-G9-6363-01A-21R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE142210_2_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
NOL6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39986
GSE148657_3_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AU-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CA-73-BW50_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.272088
GSE120413,GSE120447_4_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VI, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.919125
KIF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11765
FOXP2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
GSE147662_0_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SALL4-18804426-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K60272064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76686
BRD-K58779593	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10407
GSE102675_2_v_1_atf3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RMGI	CCLE Cell Line Gene CNV Profiles	-1.0	-2.58965
BRD-K19567079	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45606
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10975
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SB-202190-7058	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
SG in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.904288
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.3018
BRD-K29458940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05297
NCIH1436	CCLE Cell Line Gene Expression Profiles	-1.0	-1.69135
GTEX-S7PM-0526-SM-3NM92	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.873247
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12087
SNU489	CCLE Cell Line Gene CNV Profiles	1.0	1.37316
Basolateral amygdalar nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03487
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-1426-SM-4DXTX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10577
BRD-K03254663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66202
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-86-YY62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314162
GSE248887_0_v_1_dkk1_human	RummaGEO Gene Perturbation Signatures	1.0	null
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.846057
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20731
GSE195559_6_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5477-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MEL270	DepMap CRISPR Gene Dependency	1.0	8.3411
GC-54-IZ89_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296053
DD-74-PJ26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.240113
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.826931
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THUMPD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19489
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
NANOG-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE202434,GSE202438_10_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K60161601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42583
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-A9R4-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2890-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_420_KD_FOXM1_SRP239534	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.62721
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gtpase regulator activity	GO Molecular Function Annotations 2015	1.0	null
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD7_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
FOXP1	ChEA Transcription Factor Targets	1.0	null
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-449b	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
Nuclear outer membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.551
LXF-289	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996807
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXC2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.0926
GSE147959,GSE147960_5_v_3_stat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22097
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34554
Cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50588
CB-06-FE89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.220398
E2F6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A13I-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN015_MCF10A.TP53.M_24H:F21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.61135
GSE156923_2_v_3_rbmx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC89	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.973142
SOX17-20123909-XEN-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TBC/RABGAPs	Reactome Pathways 2024	1.0	null
GSE179002_4_v_1_caprin1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K16940345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01775
H3K4me3_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE226091,GSE226092_0_v_4_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K97332312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31996
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Gene_name_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4619-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196699_2_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MB-49-LL22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319065
X	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26374
GSE211989_3_v_2_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7434-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	1.0	null
CEBPB_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92974694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48346
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.924082
GTEX-R55F-1426-SM-2TF53	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44157
BRD-K66013406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.62941
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.40844
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K02866760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03014
GSE124410_6_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF_Q1_vs_Q4-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHEMBL217125	DeepCoverMOA Drug Mechanisms of Action	1.0	0.27
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0626-SM-3DB8U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3572
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K36314834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50664
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61688
PMC9314667-Table_1.xlsx-Regulons-XBP1_XBP1	Rummagene Transcription Factor Associations 2026	1.0	null
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.29898
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MM-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.41683
kidney	HPA Tissue Gene Expression Profiles	1.0	2.02066
hsa-miR-4427	TargetScan Predicted Conserved microRNA Targets	1.0	0.212286
BRD-K95735693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16449
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04796
GP5D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Bed nuclei of the stria terminalis, posterior division, transverse nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03696
GSE154577_7_v_12_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
PMC5740759-40246_2017_131_MOESM1_ESM.xlsx-Table_S2-HSF1_CanSig_Genes-HSF1-CanSig_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
496100551_PCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.53099
GTEX-WHSE-1126-SM-3NMBU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18778
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE109111_2_v_0_stim1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.891153
GSE163862_0_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.981031
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3WC-01A-31R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U3ZN-1626-SM-4DXTZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33751
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-26b-5p	MiRTarBase microRNA Targets	1.0	null
GSE90552_1_v_0_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BCL3	ENCODE Transcription Factor Targets	1.0	null
GTEX-P78B-0526-SM-2I5F7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09023
CE-96-GH46_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.289522
GTEX-PWOO-0926-SM-2I3EC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935769
Leiomyoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.526
RKO	GDSC Cell Line Gene Expression Profiles	1.0	1.59328
4-Benzylpyridine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.44396
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29C-06A-21R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.88124
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_Ctr-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K43352598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46814
BICR18	CCLE Cell Line Gene Expression Profiles	1.0	2.05847
LTBR_INHIBITION - 1 Day_GDS2004_733_mouse_Lymph nodes  (MG-430A)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BRD-K15052303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67039
GSE129370_2_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37213
BRD-K86086888	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04018
GSE162739_4_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE158197_6_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FCF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.03469
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.13885
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.99215
PBX3	ENCODE Transcription Factor Targets	1.0	null
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anterolateral visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.84186
GSE122215,GSE122217_5_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE156708_1_v_0_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
r7 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30365
GSE139966_4_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AA-48-XT80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.335472
GTEX-WYBS-0626-SM-3NMAS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58913
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72537
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830597
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hacat	HPA Cell Line Gene Expression Profiles	1.0	0.986512
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925152
Bronchus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
endometrium	HPA Tissue Protein Expression Profiles	-1.0	-0.845141
regulation of plasma membrane bounded cell projection assembly	GO Biological Process Annotations 2025	1.0	null
asiaticoside-7004	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.84892
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
AF-01-FE42_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235723
GTEX-XPVG-0526-SM-4B65N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45789
GTEx Breast 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-4.89864
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.886193
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_0_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USF1_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
pallidal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.05785
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.913714
Basomedial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04597
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.22039
GSE206516,GSE206518_2_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K52218664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30329
Spinal nucleus of the trigeminal, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.24715
ChIP_TCF3_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ES1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.47565
GSE210377_0_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28483134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54617
HSF1_KD_GDS1733_751_human_HeLa cells - 0.5 Hour by siHSF1_1	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
NUGC4	CCLE Cell Line Gene CNV Profiles	1.0	1.82879
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6D8-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157594_3_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-548x	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
GSE200673,GSE200691_1_v_5_hmga2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
intermediate stratum of r9BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10683
Perturb_5322_KD_Stag1_SRP244261	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.20247
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4698
GTEX-XLM4-2026-SM-4AT4X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91156
PMC4989457-13073_2016_339_MOESM3_ESM.xls-MITF-_SURVIVAL-hugo_id_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SR	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.980176
niflumic acid-7430	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Perturb_9702_KO_Mef2a_ERP122655	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
CEBPB_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.878944
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.48611
A-Vietnam-1203-2004(H5N1)_12Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.09082
BRD-K05246869	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07212
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.00732
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
fallopiantube_8e	HPA Tissue Sample Gene Expression Profiles	1.0	1.3322
male reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05362
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.56454
BRD-K55538850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6067
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.34078
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K19225848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18751
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4256	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
Desvenlafaxine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.36
striohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11226
GSE147876,GSE147877_2_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
15656903-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-UPK5-1626-SM-4JBHI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27931
BRD-A89947015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62822
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19006
Nr2e3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.1304
Lung adenocarcinoma_LUAD_TCGA-69-8253-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
liver	HPA Tissue Gene Expression Profiles	-1.0	-2.06114
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.957372
JURKAT	DepMap CRISPR Gene Dependency	1.0	2.00134
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QEL4-1426-SM-447AC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01176
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7825356-8844261.f3.docx-47-KLF12_KLF12	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE226316_6_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
flumequine-1429	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
15220918-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.685677
GSE221356_1_v_0_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2030	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.49288
Internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE244072_11_v_1_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K36170990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36809
r8 part of basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2574
NFYA	JASPAR Predicted Transcription Factor Targets	1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.483922
BRD-K74482064	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11972
Vagina	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BRD-K84601599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20071
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15125
r9 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36147
BRD-K27911943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04674
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6641
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.07876
BRD-K49203165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0144
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-FX-A2QS-11A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bed nuclei of the stria terminalis, anterior division, magnocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00434
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LA-09-SS14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.212806
SPECC1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15943
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K40001470	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03794
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217694_3_v_2_pold1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148200_1_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
6071_PARK7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.16122
GSE93309_1_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Bronchoalveolar system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.54309
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S12-Table_S12_MR_resluts_of_brain_pQTL_and_any_ischemic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XAJ8-0626-SM-47JY4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871687
BRD-K36055854	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66426
GSE193177_1_v_0_st266_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
orbital frontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.9927
H3K36me3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of r10Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23744
intermediate stratum of r8Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98496
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.44345
USF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5094_KO_Cbx1_SRP104194	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.40301
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59578
Brain Lower Grade Glioma_LGG_TCGA-HT-A61B-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14026
GSE228992_0_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAFF	ENCODE Transcription Factor Targets	1.0	null
GSE196505,GSE196507_1_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Colon - Transverse	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.15675
PMC6879454-Data_Sheet_1.xlsx-AA_in_vitro-Unnamed_4_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4709-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.91989
ERG	ChEA Transcription Factor Targets	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A5VG-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10683
GSE142210_4_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Wholebrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.55316
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC9013128-NIHMS1795992-supplement-4.xlsx-501mel_ARID2_KO_Downregulated-Gene__name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K24025166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27864
KLF4-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5KH-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
BRD-K87995704	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16881
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A54389315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05208
posteroventral (inferior) parietal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.69663
SRF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
BRD-K06218527	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02877
PMC6977700-aging-12-102667-s006..xlsx-Sheet1-The_identified_941_dysregulated_LmiRM-CTs_in_MI_using_traditional_method_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K92544320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03317
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.58907
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.051079
BRD-K13567350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67387
GSE147210_3_v_4_kmt2d_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.08512
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.986473
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K30436657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.34391
IM-9	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.20737
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06576
CAL27	CCLE Cell Line Gene CNV Profiles	1.0	1.44077
GSE230744,GSE237803_0_v_2_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K09258973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.89448
ChIP_POU5F1_18700969	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
ChIP_SALL4_18804426	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19352
GSE160246_9_v_5_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4756-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
BRD-K01554997	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54217
phenyl-aminosalicylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63344
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus	HPA Tissue Protein Expression Profiles	-1.0	-0.845141
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.928127
HOXC9-25013753-NEUROBLASTOMA BE2-C-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
regulation of catalytic activity	GO Biological Process Annotations 2015	1.0	null
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.879129
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X261-0326-SM-3NMD4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1896
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.7622
THAP1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ventricular hypertrophy_Myocardial tissue_GSE4678	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.74216
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.980951
FOXA2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBX3_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5651844-41467_2017_1173_MOESM7_ESM.xlsx-ZZZ3_ChIP-seq_peaks-Unnamed_7_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
white adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.595255
IV	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.997593
Primary somatosensory area, barrel field, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19224
P68-20966046-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
plagl2_17983586_small_intestine_lof_mouse_gpl1261_gds3010	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.624098
GSE162276_4_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE199255,GSE199356_4_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of cilium assembly	GO Biological Process Annotations 2023	1.0	null
intermediate stratum of r9Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33069
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC2302	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869312
GSE241701_1_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.845169
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4a-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54642
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.863483
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.868381
CRCGN011_HEPG2_24H:D07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.19753
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
GSE112760,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
17683518-193GeneTable	GeneSigDB Published Gene Signatures	1.0	null
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947114
hsa-miR-4419a	TargetScan Predicted Conserved microRNA Targets	1.0	0.050854
NCIH211	CCLE Cell Line Gene CNV Profiles	-1.0	-1.46706
Lung squamous cell carcinoma_LUSC_TCGA-34-2596-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952278
A549_BMS-536924_10µM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0108445
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
KLM1	CCLE Cell Line Gene Expression Profiles	1.0	1.48369
GSE198794_0_v_3_usp18_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7353-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EGR-1_KO_GDS3607_526_mouse_Retina - 42 Days (POST-NATAL)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE206870,GSE206872_1_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K97929312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04175
GTEX-SNMC-0926-SM-4DM5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.883532
GSE228181_2_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
lufenuron	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11927
HCC78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.973142
ZNF513	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59128
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.25764
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.956713
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5984-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7409-01A-31R-2232-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66903
GSE232631_0_v_2_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7010-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE131887_1_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SALL4-18804426_ESC-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
AC-36-SY22_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.723482
BCLAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTBP2	ENCODE Transcription Factor Targets	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.827272
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.981915
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.66867
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48081
GTEX-WFJO-0926-SM-4LVM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13041
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Blood	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.167
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_2_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.46337
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.298139
GSE154219_0_v_2_cholestyramine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ABC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.995282
GSE138815,GSE138817_0_v_2_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SETDB1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.38883
GTEX-X4XY-0226-SM-4E3IZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16691
Perturb_10280_KO_Mid1ip1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.7088
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.576
MZ in midcingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.985541
Amygdala	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.05157
Perturb_14002_KD_Dek_SRP376103	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.68771
Blood metabolite levels	GWAS Catalog SNP-Phenotype Associations	1.0	0.713153
BRD-A81260764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09995
lm9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.014
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K92950328	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00081
BRD-K04785821	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17098
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MFH-ino	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.37912
EP300	ENCODE Transcription Factor Targets	1.0	null
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856734
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.36388
GSE137818_5_v_1_brca2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K20624967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34005
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6090-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.21748
intracellular protein transport	GO Biological Process Annotations 2025	1.0	null
GSE248659_1_v_0_klf5_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08461
BRD-K50157358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19733
MZ in rostral cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.43535
KMS-28PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.883685
CCND1-20090754-RETINA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
BRD-A71590475	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22923
SP4	ENCODE Transcription Factor Targets	1.0	null
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WL46-0126-SM-3TW8I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875877
IE-80-DC24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.270073
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.78695
hsa-miR-1268	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Acute Myeloid Leukemia_LAML_TCGA-AB-2863-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12014_KO_Pgrn_SRP371359	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.8268
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_11_ZZZ3_ChIP-seq_in_shZZZ3-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01366
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIB, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.08115
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38725
H3K9ac_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
r9 part of the basolateral reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10683
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14839
superficial stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39533
Bed nuclei of the stria terminalis, anterior division, ventral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09257
hsa-miR-485-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.254633
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZC3H13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03322
KA-29-AB08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.427745
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PRIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0186
GSE162739_8_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_1_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE199204,GSE211619_4_v_1_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.36997
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210655_1_v_6_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE103122_0_v_1_riok3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-NJ-A55R-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE140607_1_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1437_LUNG	CCLE Cell Line Proteomics	1.0	3.67922
NR1H3-23393188-ATHEROSCLEROTIC-FOAM-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YW-0326-SM-2I5EI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853935
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.74638
GTEX-UJMC-0326-SM-3GAE2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.874831
GTEX-OIZI-0526-SM-2XCEG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881121
GSE122067_3_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-2626-SM-2I3EV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.951694
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A5UD-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-P44H-0326-SM-2XCES	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02434
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A7IP-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.86651
GSE112761,GSE112767_1_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
18504433-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.889009
hsa-miR-4465	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
Uterine Carcinosarcoma_UCS_TCGA-N8-A56S-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T8EM-1826-SM-4DM7F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07219
GTEX-U3ZN-0926-SM-4DXTU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882015
GSE148066,GSE157787_8_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50887
AC-35-CK01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.1874
A3/KAW	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.888507
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.900189
BRD-K00505499	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18855
cerebellar cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43532
DB	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49573
GSE154767_4_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K65137277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11777
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47885
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KM-H2	GDSC Cell Line Gene Expression Profiles	-1.0	-2.11068
GTPase activator activity	GO Molecular Function Annotations 2025	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE199921_1_v_0_romidepsin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6591-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6T8-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of organelle assembly	GO Biological Process Annotations 2015	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.433308
PMC4944136-srep28995-s2.xls-DUXA-gene_DUXA	Rummagene Transcription Factor Associations 2026	1.0	null
THAP4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20196
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237655
GTEX-XXEK-0926-SM-4BRWH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04072
CRCGN015_HEPG2_48H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.49165
BRD-K04095185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15048
PMC10534007-Table_2.xlsx-S6_unique_down_MSC_B-914_elements_included_exclusively_in_BFTC905_MSC_down_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
NCIH1693	CCLE Cell Line Gene Expression Profiles	-1.0	-2.13756
Endopiriform nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27757
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC38	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.925303
SMAD2	ChEA Transcription Factor Targets	1.0	null
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.18658
BRD-K50604515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73477
BRD-K00667983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04113
BRD-K76618080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2657
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64973
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_205_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
ND-15-RC31_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.353882
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lung	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTPase regulator activity	GO Molecular Function Annotations 2023	1.0	null
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.0177
hsa-miR-4269	TargetScan Predicted Conserved microRNA Targets	1.0	0.90397
Yolk	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.844
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
JB-75-NC66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229122
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.23839
H3K9me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-449a	TargetScan Predicted Conserved microRNA Targets	1.0	0.15008
DE-34-DT75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.437064
GSE124410_2_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEC-1-A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ASGR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08043
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PXR (PXR:RXR)	MotifMap Predicted Transcription Factor Targets	1.0	null
periventricular stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67819
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F0-01A-12R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SARS-BatSRBD_72Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.63873
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29143
TP73	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.26
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.835142
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
301_ANAPC10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.520636
bufexamac-5515	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE126463_1_v_3_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX	ENCODE Transcription Factor Targets	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE8	CCLE Cell Line Gene CNV Profiles	1.0	1.3326
CCT4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15969
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17402
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
RD	CCLE Cell Line Gene Expression Profiles	1.0	2.38996
Mesothelioma_MESO_TCGA-TS-A7PB-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
NCIH1793	CCLE Cell Line Gene Expression Profiles	1.0	2.84947
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3B4-01A-12R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_17046_KD_GORASP1_SRP201887	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
SIX5_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_15410_KD_GATA2_SRP043960	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.5091
YY1	ENCODE Transcription Factor Targets	1.0	null
GSE112761,GSE112767_1_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K78658063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.98606
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE146072_0_v_1_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XK95-0226-SM-4AT58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.83364
TCF3-18692474-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
496100425_TCx_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.21915
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RVPU-2426-SM-2XCAR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08997
496100538_HIP_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.5098
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perikaryon	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.571
Female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Blood platelet	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.167
regulation of cell morphogenesis	GO Biological Process Annotations 2015	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
GSE190384,GSE190386_6_v_4_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
OLIG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02514
GSE124410_6_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GM12878	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.1398
BRD-K98087319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22222
4578_LIG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.698192
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE86507,GSE86509_7_v_9_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.982352
GTEX-S7SE-0011-R4A-SM-2XCDB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.50802
Vdr	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	38.5868
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3121-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.042355
GTEX-NPJ8-1526-SM-2D7VU	GTEx Tissue Sample Gene Expression Profiles	1.0	2.0428
BRD-K66327237	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49022
WDR12	Pathway Commons Protein-Protein Interactions	1.0	null
oleandomycin-2018	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K29301364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43247
BRD-K96575636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27632
dorsolateral prefrontal cortex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.898561
r7 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76754
SNB75	BioGPS Cell Line Gene Expression Profiles	1.0	2.03854
GSE206870,GSE206872_3_v_5_ascl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TPMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.28428
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63704
SK-MM-2	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.62853
EIF2S3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34724
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228727_2_v_1_dapagliflozin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
kidney_a	HPA Tissue Sample Gene Expression Profiles	1.0	2.19497
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_58_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7660-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210101,GSE210114_2_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
orbital frontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.86656
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888175
LLGL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41889
primary somatosensory cortex (area S1, areas 3,1,2)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.77042
GTEX-O5YV-1126-SM-3LK73	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91649
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amidopyrine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22347
USF2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.16888
Pallidum, dorsal region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02483
SNU1076	CCLE Cell Line Gene CNV Profiles	1.0	2.19022
BRD-K77797840	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1975
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD2-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
USF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CE-00-EK89_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281648
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K63401627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07188
GSE219195_1_v_3_rbm12_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.33129
GSE203329_2_v_1_mettl5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_9517_Mut_Sall4_ERP111723	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.1299
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE196699_7_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17508
SK-MEL cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.821
HCCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10656
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836757
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VI	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20267
Skin Cutaneous Melanoma_SKCM_TCGA-QB-A6FS-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TH-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
QX 314	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.43
MYC	ChEA Transcription Factor Targets	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53682
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A8YO-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
gonad	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superficial stratum of r8BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98496
BRD-K91917132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89136
CC-70-BD07_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218281
superficial stratum of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04882
GSE182680,GSE182683_5_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FOXA3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2551
TGFBR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21085
VZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31692
H3K4me3_CD3 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Globus pallidus, external segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00957
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37006
Brain Lower Grade Glioma_LGG_TCGA-TM-A84H-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39701
MAFK_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE132948,GSE132949_4_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172020_0_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Central amygdalar nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.90623
FOXA2	ENCODE Transcription Factor Targets	1.0	null
positive regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20623
GSE225218_8_v_3_abcb1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RPF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.85321
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Thymus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.84178
GTEX-WFON-0126-SM-4LVM9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884539
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8755
MAX_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
magnocellular (medial) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03909
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_0_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10778
MD MB231	BioGPS Cell Line Gene Expression Profiles	1.0	1.32697
USF1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RM2N-1626-SM-2TF5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28629
GSE169155_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE71385_1_v_0_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CAL-62	GDSC Cell Line Gene Expression Profiles	1.0	1.84887
BRD-K46942548	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13364
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A182-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NE-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
GSE152432_6_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154577_7_v_9_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K93747042	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12361
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.840265
GTEx Skin 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-13.5876
Perturb_17366_KD_SRSF6_SRP309439	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.1662
A172	BioGPS Cell Line Gene Expression Profiles	1.0	0.890514
Pituitary	GTEx Tissue Gene Expression Profiles 2023	1.0	1.42736
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-A76O-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5884-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09597
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6131-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POYW-0726-SM-2XCEO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10761
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997954
A172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.4748
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE184884_6_v_0_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA92593	DeepCoverMOA Drug Mechanisms of Action	1.0	0.86
Intracellular organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
r8 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76754
GTEX-RNOR-2326-SM-2TF4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46991
Lung adenocarcinoma_LUAD_TCGA-62-8399-01A-21R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXO4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.3369
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRDM14-21183938-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_1573_KO_Ctr9_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.60804
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.71898
GTEX-XUZC-0126-SM-4BOO6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896256
MDA-MB-330	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.42374
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE166004_3_v_2_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3910540-725780.f1.xlsx-Table_S6-Human_orthologs_of_the_genes_in_the_core_module_and_the_genes_in_the_MYC-centered_module_in_ES_cells_Kim_Woo_et_al_2010_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_9714_KO_miR34a_SRP058984	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.26324
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ED-15-OX47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219022
Organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
BRD-K37564297	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63539
CHTF18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.84571
fusiform gyrus, left, bank of cos	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.824775
FOXO6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.0947
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08552
TP53INP2_KO_GDS5053_277_mouse_Skeletal muscle - SKM-KO	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
inner SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.910711
G112	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869312
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
MON2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14545
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
activation of GTPase activity	GO Biological Process Annotations 2023	1.0	null
PMC6555970-40246_2019_210_MOESM1_ESM.xlsx-LF_genes_R_genes-Common_genes_in_all_R_species_not_found_in_common_genes_of_LF_species_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
VIIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.938128
FOXA1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.73167
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.59024
E2F6	ENCODE Transcription Factor Targets	1.0	null
parahippocampal gyrus, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.931985
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.12851
SARS-CoV_96Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.84975
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.068274
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.66591
NFATC1	ENCODE Transcription Factor Targets	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CQ-7071-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
G361	CCLE Cell Line Gene CNV Profiles	1.0	1.4168
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.68183
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05308
PMC5550424-41467_2017_212_MOESM4_ESM.xlsx-Hematlas-Genesets-ZNF257_ZNF257	Rummagene Transcription Factor Associations 2026	1.0	null
PAX5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-150	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K36me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SCC-25	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.52797
Helam	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.851
MAX_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47869
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845723
GSE71468,GSE76476_2_v_3_rbfox1_human	RummaGEO Gene Perturbation Signatures	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3387-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1937	DepMap CRISPR Gene Dependency	1.0	2.92643
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A498	BioGPS Cell Line Gene Expression Profiles	1.0	1.35429
MAZ	ENCODE Transcription Factor Targets	1.0	null
GSE186483_2_v_0_lrrk2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.22217
BRD-K04238122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20538
parietal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.875071
SKES1	CCLE Cell Line Gene CNV Profiles	1.0	2.15564
r7 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2183
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skmel30	HPA Cell Line Gene Expression Profiles	-1.0	-1.02603
cerebellar cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04996
GTEX-REY6-0826-SM-2TF4S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35816
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6VC-01A-23R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
ABHD14B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45491
BRD-K87669186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2099
Lung squamous cell carcinoma_LUSC_TCGA-98-A53A-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-94-GN01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.299735
Early phagosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.225
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
dorsolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.49406
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10232
HCE4	DepMap CRISPR Gene Dependency	1.0	2.25345
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BHLHE40_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3714	TargetScan Predicted Conserved microRNA Targets	1.0	0.034317
USF1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53INP2_KO_GDS5053_544_mouse_skeletal muscle	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.24386
CD2AP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15605
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04191
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.62378
biological_process	GO Biological Process Annotations 2015	1.0	null
GSE144115_4_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AG-2926-SM-2HMJ3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48478
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-0926-SM-48TBS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45872
GTEX-X585-3026-SM-46MWF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27099
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K33710385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03395
Perturb_5098_KO_Cbx5_SRP104194	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.7473
BRD-K11297155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83044
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-0526-SM-2I3EH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44763
GSE179031_3_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_RAD21_21589869	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-PVOW-0008-SM-48TE8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12689
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5581-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
GTEX-PW2O-0226-SM-48TC7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27577
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4523_KO_Dpf2_ERP105019	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.68771
GSE234514,GSE234516_2_v_0_mitf_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-CH-5771-01A-21R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOSL2::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7222
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K89305325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12734
GSE151612_4_v_8_pracinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ChIP_PRDM14_21183938	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
RUNX1	ChEA Transcription Factor Targets	1.0	null
BRD-K42508877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27214
mantle zone of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08104
GTEX-UPK5-2026-SM-4JBIM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852785
Liver hepatocellular carcinoma_LIHC_TCGA-EP-A2KB-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRO-0226-SM-3LK6F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9722
BRD-K41334119	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.57678
BRD-K94697940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00291
raphe magnus nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.87488
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SLC25A15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.87563
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5818
PMC9546828-41389_2022_435_MOESM5_ESM.xlsx-Table_S4-Table_S4_Upregulated_genes_upon_ZNF148_knockdown_P_adj_0_05_Fold_change_1_5_ZNF148	Rummagene Transcription Factor Associations 2026	1.0	null
8330_SPATS2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.510863
OVCAR5	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.06084
ChIP_NANOG_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Rab regulation of trafficking	Reactome Pathways 2024	1.0	null
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-PR-A5PF-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GATA2_01_61	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60426
SG in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.61821
SIN3A	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MP-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47607
salivarygland_6c	HPA Tissue Sample Gene Expression Profiles	1.0	0.915132
NUGC-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.964425
HEC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02524
GTEx SalivaryGland 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-3.33405
TCF12_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PORCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.86461
POLR2AphosphoS5_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QC-63-VN72_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.224287
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cochlear nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.957276
NFIC	ENCODE Transcription Factor Targets	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JW-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-VJYA-0726-SM-4KL1T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.881058
SNU-398	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869312
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC3964217-oncotarget-05-417-s001.xls-Supplemental_Table_3-GABPA-bound_promoters_GABPA	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AI-0326-SM-2I3EK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18033
r9 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76754
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.971477
BRD-K65464642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5695
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02375
ELF2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15609
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4878_OE_BCL2L1_SRP131666	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.68933
GSE111385_2_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23758
BEN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.20747
POU5F1-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung adenocarcinoma_LUAD_TCGA-44-7671-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Superior temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.02
NCI-H1688	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.51576
Cardiomyopathy_Myocardial tissue_GSE1869	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.73827
GSE149359_2_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154767_2_v_0_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.87913
EC-96-KI84_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21384
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
23132/87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01097
X, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.00328
BRD-K43186783	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59716
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
GTEX-WWYW-3126-SM-3NB39	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76111
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30125
GSE131887_5_v_2_doxycycline_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K43926323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2576
GSE111102,GSE111105_3_v_5_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ETV1_01_161	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	1.24883
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.89694
TRIM28_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-SOX2_targets_enrichment-Unnamed_192_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
SMAD3-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE185139_1_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.103895
H3K79me2_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X8HC-2826-SM-46MWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03278
NOTO	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4722
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.04226
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.34863
hsa-miR-4725-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Dorsal column nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48081
VMRCRCZ	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62045
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.47358
hsa-miR-4253	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08481
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06678
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE112761,GSE112767_4_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	1.0	null
Serum metabolite levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	1.1
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE154577_6_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48081
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
protein localization	GO Biological Process Annotations 2025	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.54603
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.823408
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.87391
PCNA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.35663
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K10130686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64054
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.433021
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE166294_0_v_1_etv5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	25.7872
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KAT2A	ENCODE Transcription Factor Targets	1.0	null
GSE154577_2_v_10_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC2998	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.50308
BRD-K33757887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59605
GSE160001,GSE160670_3_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE224004,GSE224005_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FRAT2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.48679
CFPAC-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.89175
Rectum adenocarcinoma_READ_TCGA-F5-6861-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPL-1626-SM-2HMIR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.953435
olfactory bulb	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.975811
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.29914
BX 471	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.53
NCOA6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.67612
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE158834_1_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.390855
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158969_1_v_2_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_1_ZZZ3_ChIP-seq_peaks-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-2.19362
184B5	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.02832
GTEX-Q2AI-1126-SM-48U19	GTEx Tissue Sample Gene Expression Profiles	1.0	1.4363
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34207
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.872862
SMC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02283
GTEX-RWSA-2026-SM-47JX8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16246
basolateral amygdaloid nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.62895
BRD-K94344573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43041
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S4Q7-1026-SM-4AD75	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00087
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U4B1-0126-SM-4DXSN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987529
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K76677554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72916
PMC4090731-bjc2014262x1.xls-Sheet1-CaSig-HSF1_Positive_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VUSG-1526-SM-4KKZH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45713
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sodium arsenite	CTD Gene-Chemical Interactions	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.12304
BRD-K73899967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09068
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE205070_2_v_5_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
496100457_TCx_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.17404
mediodorsal nucleus of thalamus_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01875
BRD-K52259096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48538
GSE158834_10_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-05-4384-01A-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.906355
GTEX-SIU7-1126-SM-2XCDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06086
BRD-K57343972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27024
11060_NON-TARGETING_NON-TARGETING	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.500781
GTEX-T6MN-2626-SM-32PMQ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.77205
hsa-miR-1321	TargetScan Predicted Conserved microRNA Targets	1.0	0.09606
SP4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41922
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Vandetanib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163315
caco2	HPA Cell Line Gene Expression Profiles	1.0	1.41402
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21733
hsa-miR-3180	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
skeletalmuscle_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.997221
Entospletinib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.52
CEBPB-21427703-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SISO	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.44268
BRD-K61168922	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47999
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.844989
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.73899
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E1-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE190384,GSE190386_2_v_4_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
POU5F1-18700969-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-A4M1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.TP53.M_24H:A14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.39547
hsa-miR-4441	TargetScan Predicted Conserved microRNA Targets	1.0	0.039622
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_NANOG_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE147943_7_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RKO	CCLE Cell Line Gene Expression Profiles	1.0	1.4074
hsa-miR-4728-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.09606
GSE140092_0_v_1_socs3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K75610411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10477
primary motor cortex (area M1, area 4)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.898011
AE-42-HT01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.369306
u	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.721
GTEX-XOTO-0726-SM-4B659	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.825036
Prostate adenocarcinoma_PRAD_TCGA-J9-A8CL-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K89767945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26116
IZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24672
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5-23275557-MAMMARY-EPITHELIUM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K31273080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35033
Uvula (IX), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37743
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K91799761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12773
BRD-K23589316	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27562
SG in rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09659
SMAD3	ChEA Transcription Factor Targets	1.0	null
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A6Z0-01A-13R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKN74	DepMap CRISPR Gene Dependency	1.0	2.82118
GSE114690_1_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K30963311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32438
GSE226249_2_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905549
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4741-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:N03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	3.11309
GSE195559_2_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.68231
GSE210101,GSE210114_7_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Ppara	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.851
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SH-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-4679-01B-01R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37023
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-KLF4_Targets_Enrichment-Unnamed_135_KLF4	Rummagene Transcription Factor Associations 2026	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
Perturb_4520_OE_Jarid2_SRP281895	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.94222
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-A59449038	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00395
BRD-A81615860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17947
peripeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54875
striatum_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45263
STAT3-18555785-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3136-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
GSE211425_1_v_0_mettl3_human	RummaGEO Gene Perturbation Signatures	1.0	null
STAT3_01_168	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	8.94813
intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
Lung squamous cell carcinoma_LUSC_TCGA-77-8144-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PTGIS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46958
BRD-K56426074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65865
JURLMK1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.05595
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.828808
PSIP1_Deficiency_GDS2883_633_human_T-cell line	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
FOXP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1546
MITF	ChEA Transcription Factor Targets	1.0	null
MZ in granular insular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52314
CRCGN017_MCF10A.TP53.M_24H:A10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.08847
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48081
BRD-K13196166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1102
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14455
outer SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.25003
ChIP_TCF3_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K39685923	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28485
MYC-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5988-11A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KAT2B	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
upper (rostral) rhombic lip	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.879684
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
JAK1_activemutant_61_GSE18239	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.59243
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R53T-0526-SM-3GADL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75583
GSE210655_3_v_5_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
1966_CUL7_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.02966
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45643
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80Q-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
2205_DHX29_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.554031
CHD1	ENCODE Transcription Factor Targets	1.0	null
HCC44	DepMap CRISPR Gene Dependency	1.0	2.02263
CALU3	CCLE Cell Line Gene Expression Profiles	-1.0	-2.05418
15735024-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BCL11A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9403
CiliaryGanglion	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.47
BRD-K29661539	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42264
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51370144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21258
lateral part of r7B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08104
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A3EV-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAKI1	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.13351
BRD-A86977540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.1183
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.439375
BRD-K99982687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0481
Esrrg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	32.02
BRD-K90877053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15312
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
4-Methylhistamine	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.36
GSE172020_1_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.30776
hsa-miR-4271	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23861
BRD-K76543697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19167
BRD-K96249452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22807
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11203
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5966-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAL1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07599
amygdaloid complex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.49335
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K30973947	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12425
AtrioventricularNode	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.27739
ChIP_KLF4_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.3534
Thyroid gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GTEX-RVPU-0011-R10A-SM-2XCAH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23769
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996807
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMIZ1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1	ChEA Transcription Factor Targets	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.872862
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
osteoclasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.54357
NUP153	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00815
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
19074828-TableS4	GeneSigDB Published Gene Signatures	1.0	null
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.912943
cefprozil	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25539
Rectal gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.937
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50562
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.32675
MYC_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KE39	CCLE Cell Line Gene CNV Profiles	1.0	1.39664
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AQ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157894_1_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-18-3421-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
BRD-K73577714	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06609
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195582_3_v_1_pim1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SU-DHL-8	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NKX2-5-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ZKSCAN3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	50.8571
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.281986
BRD-K77892972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29375
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KLF4-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE86021_1_v_2_crenolanib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ChIP_NR0B1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K32118188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69577
PMC8987207-DataSheet_1.xls-TF_targets_Fig_2A-E2A_Pre-Pro-B-Cells_ChIP-seq_TCF3	Rummagene Transcription Factor Associations 2026	1.0	null
thyroid	GTEx Tissue Gene Expression Profiles	1.0	0.828654
Nr2f6	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	62.8182
GSE239844_6_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NDT 9513727	DeepCoverMOA Drug Mechanisms of Action	1.0	0.42
BRD-K55393423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18118
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.185678
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10245467-mmc3.pdf-35-ELK1_ELK1	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.925059
GTEX-N7MT-0011-R10A-SM-2I3E1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950828
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16657
GSE122067_2_v_1_mtch2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HE-80-BQ08_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.463473
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31678
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
CAL-12T	GDSC Cell Line Gene Expression Profiles	1.0	1.98698
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_18560_KO_Zfp36l3_SRP055207	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.43317
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
pancreas	HPA Tissue Gene Expression Profiles	-1.0	-1.11306
CCNT2	ENCODE Transcription Factor Targets	1.0	null
Rhox11	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	17.4607
H3K4me1_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.03284
BRD-K28535931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26506
BRD-A59391763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30834
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42766
BRD-K08442552	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82381
FLI1_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4291	TargetScan Predicted Conserved microRNA Targets	1.0	0.062888
GSE206516,GSE206518_6_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186707_1_v_0_hdac4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4944136-srep28995-s2.xls-ARGFX-gene_ARGFX	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	2.51471
Perturb_9447_KD_ESR2_SRP275562	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.17359
PEER	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92345
GSE210101,GSE210114_6_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Basomedial amygdalar nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0705
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869312
496100485_PCx_possible Alzheimer's disease_no TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.28683
GSE119603_1_v_0_oxaliplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
3-Benzyloxyaniline	DeepCoverMOA Drug Mechanisms of Action	1.0	0.25
GSE171175,GSE171181_1_v_0_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K13938991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51677
GSE198165,GSE198166_8_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
DBF4B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06894
Piriform-amygdalar area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27098
H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LXR-22292898-THP-1-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K82244940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41054
GTEX-XOTO-0011-R8A-SM-4B65J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839563
BRD-K83916197	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3288
testis_7a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.29827
BRD-K46970272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09832
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.2119
CEBPB_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6134-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
Perturb_15587_KD_EP300_SRP355992	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.96581
r8 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.98496
Mouth	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
SNU1076	DepMap CRISPR Gene Dependency	1.0	2.26516
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26296
GA-04-JM33_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.235852
ARGFX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.973
III	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.837869
H3K4me3_Breast Myoepithelial Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3118	DepMap CRISPR Gene Dependency	1.0	2.05368
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A71E-01A-31R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.13519
GSE117042_0_v_3_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
amygdaloid complex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.37932
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-3175	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE111247_2_v_8_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC12753515-Table2.XLSX-G5-specific_down_only_top_500-EGR2_EGR2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K47906308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60983
TBC1D13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06908
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMAD2-18955504-HACAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.5432
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.983854
NARF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18082
PCLAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19449
ChIP_NANOG_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K70533557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44428
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0038
H3K4me1_H1 BMP4 Derived Trophoblast Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
todralazine-5512	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE174522_1_v_0_spp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAL 54	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.919862
dorsolateral prefrontal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.853862
GSE71491_0_v_1_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36706
ROCK_INHIBITION_GDS3944_462_mouse_Forebrain astrocytes - 6 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
HAP-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.342
Perturb_10279_KO_Lyplal1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.8779
GSE95685_2_v_5_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_10_v_8_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LE-80-QM43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.231204
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04391
H4K20me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CFPAC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.5894
DD-74-PJ26_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.424487
Perturb_2798_KD_TRPS1_SRP125141	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
r8 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.39533
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47056
GSE135030_8_v_1_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K85513726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28283
STAT5A	ChEA Transcription Factor Targets	1.0	null
GC-04-UF36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226297
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.19764
GTEX-XBEW-0126-SM-4AT66	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02111
etodolac-1407	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B2-5636-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58371
TCF3-18467660-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
molecular function regulator	GO Molecular Function Annotations 2015	1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.81211
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.19212
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7028
STAT5-23275557-MAMMARY-EPITHELIUM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE197571_3_v_1_foxm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.976468
Perturb_1564_KO_Tnfaip3_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.19644
oral mucosa	HPA Tissue Protein Expression Profiles	-1.0	-0.845141
Adult_Liver	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.64971
BRD-K12202458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04867
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27817
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04221
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YS-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Arnt::Hif1a	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	14.2212
dorsolateral prefrontal cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.82454
superficial stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11783
OVCAR-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.81978
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETV7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.1302
macrophage	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.75004
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
spinalcordupper	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.962175
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K58242935	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2684
BRD-K63716942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42124
mediodorsal nucleus of thalamus_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.79921
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50212643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93335
GSE112860_5_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-506	TargetScan Predicted Conserved microRNA Targets	1.0	0.17031
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A9FU-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.19804
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QT-2626-SM-2I3FM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04227
BRD-K84800135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16867
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.959536
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149769_1_v_0_nlrp12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPD	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7032
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100405_TCx_probable Alzheimer's disease_no TBI_88_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32278
amygdaloid complex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.8615
BMS 303141	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.22
GTEX-UTHO-2726-SM-4JBH9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07095
MOLT-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE203158_0_v_14_aire_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SMAD1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE199255,GSE199356_3_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12224929-ADVS-12-2416784-s006.xlsx-DEG_circGLIS3_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K14813155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56471
GSE128730_7_v_2_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
BRD-K74285424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35572
III, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.38089
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_40_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.289973
ETCC016	DepMap CRISPR Gene Dependency	1.0	2.78647
SKMEL1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57743
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35545
GSE158834_7_v_13_palm_human	RummaGEO Gene Perturbation Signatures	1.0	null
UMRC6	CCLE Cell Line Gene Expression Profiles	1.0	1.85465
NCI-H2373	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.20017
KAT2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
rostral ventral respiratory cell group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40719
GTEX-X638-0426-SM-47JY2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894713
PGK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01091
GTEX-XMK1-0626-SM-4B65A	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835344
GSE112860_5_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_5321_KD_Stag1_SRP244261	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.20015
ELK1	ENCODE Transcription Factor Targets	1.0	null
U118MG	DepMap CRISPR Gene Dependency	1.0	2.60857
BRD-K41192068	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21102
GSE110178_4_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
doxorubicin_homo sapiens_gpl570_gse46493	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
3649_HBE1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.695069
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K06237859	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1868
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05192
Papillary renal cell carcinoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.971
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-518a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
GSE148066,GSE157787_11_v_7_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GlobusPallidus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-2.24846
PMC5059470-ncomms12992-s6.xlsx-CRS-NOCRS-Supplementary_Data_5_Integration_Frequency_in_cirrhotic_CRS_and_non-cirrhotic_no-CRS_Tumor_Samples_TWIST1	Rummagene Transcription Factor Associations 2026	1.0	null
PPCS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25072
hsa-miR-920	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.874061
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.4829
PMC10204296-13578_2023_1034_MOESM16_ESM.xlsx-Black-ZNF671_ZNF671	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7432-11A-01R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF21-26020271-SMOOTH-MUSCLE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE146156_2_v_3_tagap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.60916
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00043
H3K9ac_Muscle Satellite Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K41946683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1033
PMC7029036-41598_2020_59469_MOESM2_ESM.xlsx-NR4A1_vs_GFP_adj_pval_0_05-Gene_NR4A1	Rummagene Transcription Factor Associations 2026	1.0	null
Temporal gyrus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.015
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.38098
POU1F1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.331
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GP2D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-8071-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUDS3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.02709
MHHCALL3	CCLE Cell Line Gene Expression Profiles	1.0	1.38061
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FAM86C2P	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.05105
USF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4690-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
RBM15_02_143	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59797
VIIB	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.887815
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney Chromophobe_KICH_TCGA-KM-8440-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE124410_2_v_4_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RU1J-0226-SM-2TF5Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.973718
Lung adenocarcinoma_LUAD_TCGA-49-6767-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HSC-39	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.94898
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.00938
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.852938
SKCO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38557
GSE120413,GSE120447_0_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-VUSG-0726-SM-3GIK1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05854
r8 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45643
NCI-H820	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.916919
A-VN-1203-2004(H5N1)_Day1-10^2pfu_22074594_GSE33263	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.81884
BRD-K79730625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81319
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPIC-0226-SM-3GADO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31096
BRD-K95798946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46751
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44294
hsa-miR-491-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
kidney_b	HPA Tissue Sample Gene Expression Profiles	1.0	1.4541
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.944075
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
adipose tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.439507
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_9_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K36782804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01567
BRD-K70093308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.09858
GSE146074_6_v_3_ly6e_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Squamous cell carcinoma of mouth_Oropharynx Epithelium_GSE3524	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.94371
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE255680_2_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMAD3-18955504-HaCaT-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE206516,GSE206518_6_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-WQ-A9G7-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210101,GSE210114_11_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K32882942	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33848
HCV JFH1_168Hour-Huh7_None_GSE29889	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.53162
Membrane Trafficking	Reactome Pathways 2024	1.0	null
GSE223008_9_v_8_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE113329,GSE113335_3_v_4_taf6l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CAKI-1	GDSC Cell Line Gene Expression Profiles	-1.0	-2.37917
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28721
intracellular organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
hsa-miR-3120-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.03694
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
temporal pole, left, medial aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.887747
amygdaloid complex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.0378
Adrenocortical carcinoma_ACC_TCGA-OR-A5K2-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.92627
EGR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203-2004(H5N1)_18Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.08286
appendix	HPA Tissue Protein Expression Profiles	-1.0	-0.845141
GSE154577_2_v_5_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_0_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
AM 630	DeepCoverMOA Drug Mechanisms of Action	1.0	0.39
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.62935
hsa-miR-1205	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865373
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE226249_2_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2786-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
open-angle glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
NCIH854	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48911
claustrum, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.57559
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0926-SM-4E3JD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.986552
BRD-K79202867	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69583
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_145_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
SF172	DepMap CRISPR Gene Dependency	1.0	3.73375
GSE255680_1_v_0_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
WM-115 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.602
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.17604
GTEX-RVPV-0011-R3A-SM-2TF63	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6414
GSE158834_0_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51978501	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.66279
GSE132948,GSE132949_0_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.13609
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.37031
J82	CCLE Cell Line Gene Expression Profiles	1.0	1.55871
BRD-K18686200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08204
PMC12500496-262_2025_4178_MOESM2_ESM.xlsx-THP1_enriched_for_CVGBM-gene_name_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.05386
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
496100555_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.21012
superficial stratum of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19091
Vascular Diseases	CTD Gene-Disease Associations	1.0	1.04163
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3JX-01A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.04802
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K28698418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02786
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PANC0403_PANCREAS	CCLE Cell Line Proteomics	1.0	5.71884
GTEX-P4QT-1326-SM-3NMD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80836
BICR31	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.559
PMC12356745-12015_2025_10896_MOESM2_ESM.pdf-203-ZNF79_ZNF79	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BB65-RCC	GDSC Cell Line Gene Expression Profiles	-1.0	-1.67201
GSE112860_0_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ABI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88377
GTEX-QXCU-0926-SM-48FEP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.854417
Kidney Chromophobe_KICH_TCGA-KM-8443-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FC-13-VS25_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.769826
KMOE-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.44592
GSE229468,GSE229471_0_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	1.0	null
USF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-17-WP43_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.353142
FOS::JUND	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.9942
YBX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17637
POU5F1-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE128730_4_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE212760_0_v_1_fxr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64869
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2909
Central amygdalar nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24733
GSE168918_1_v_0_tmprss4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2228	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.98992
PRDM14-21183938-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
VP229	DepMap CRISPR Gene Dependency	1.0	2.74904
H3K36me3_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X8HC-0526-SM-4E3JA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02299
GSE245270_1_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAL1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE210101,GSE210114_5_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-MN-A4N5-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC12339377-41587_2024_2403_MOESM3_ESM.xlsx-TableS6_LPS_screen_GEPs-Unnamed_26_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
CAS-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.22648
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K44121468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28998
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914987
intermediate stratum of r8Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06188
membrane-enclosed lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPB_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26639
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.29
SIN3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K85720719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74293
regulation of organelle assembly	GO Biological Process Annotations 2025	1.0	null
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT20	CCLE Cell Line Gene Expression Profiles	1.0	1.87413
PAX5	ENCODE Transcription Factor Targets	1.0	null
MZ in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.08715
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.04829
GSE133683_1_v_0_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_4409_KD_LSG1_SRP187955	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.0798
CA-42-YI34_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.218329
ATP6V1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07511
BRD-K63252672	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37445
Perturb_421_KD_MYBL2_SRP239534	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.0393
8842_TFCP2L1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.699145
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21935128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05372
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TKKK	DepMap CRISPR Gene Dependency	1.0	5.79857
GSE220520_6_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
4893_MCEE_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.551395
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2GT-06A-12R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
hsa-miR-661	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00433
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3361
Prostate adenocarcinoma_PRAD_TCGA-EJ-5503-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Posterior midgut	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.67
estradiol_homo sapiens_gpl570_gse16683	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Vilazodone	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.33
CEBPB_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K06367273	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04685
BRD-A07952294	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03368
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.623858
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22489
FGFR1_activemutant_58_GSE17916	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.75801
GTEX-V1D1-0926-SM-4JBHQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.859442
FOS	ENCODE Transcription Factor Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A2NF-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKHEP1	CCLE Cell Line Gene Expression Profiles	-1.0	-2.23992
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K71537757	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04654
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
regulation of developmental process	GO Biological Process Annotations 2015	1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.49741
GSE130081,GSE130082_5_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A194-01A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nr2e1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5444
molecular_function	GO Molecular Function Annotations 2015	1.0	null
GTEX-XOTO-2126-SM-4B64U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47157
GSE218879_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K54922310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.96196
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77797589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89983
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
wt1_17420277_e11dot5_urogenital_ridge_lof_mouse_gpl1524_gds2747	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.212023
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.437971
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76754
GSE186440,GSE186443_4_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
UNC13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19718
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90352
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
ChIP_KLF4_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K48764596	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19249
BRD-K37721603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46826
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.900498
PK-45H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00849
TAL1_megakaryocyte_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	3.35821
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845871
NUGC2	CCLE Cell Line Gene Expression Profiles	1.0	2.26071
SB-92-FF15_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.287349
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.78152
GSE112760,GSE112767_4_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06097
Thyroid gland disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.032
GSE80537_3_v_2_adhfe1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Pseudopodium	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.982
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
SRF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
foxa1_23539448_lncap_lof_human_gpl10558_gse37314	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.13494
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-4115-11A-01R-1758-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	-1.0	null
klf4_17017123_rko_gof_human_gpl96_gds1942	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.552219
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40046
USF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K40558736	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18863
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19091
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.94546
ZFP281-18757296-E14-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE125782_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.02277
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.12173
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.52267
GTEX-RNOR-0926-SM-2TF56	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878564
BRD-K47443098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61023
multiform (lateral) division of MD	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.900584
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
liminal part of the r8 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09597
BRD-K76984291	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9266
In situ carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.022
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.877213
Brain Lower Grade Glioma_LGG_TCGA-TQ-A7RR-01A-21R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.43709
GSE132948,GSE132949_2_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6214-01A-41R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-0426-SM-4AT4I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84831
regulation of cell projection assembly	GO Biological Process Annotations 2015	1.0	null
BRD-K19264579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4799
VSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.362
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1355	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.16488
Ovary	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.98317
FOXO1	ChEA Transcription Factor Targets	1.0	null
small intestine	HPA Tissue Protein Expression Profiles	-1.0	-0.845141
NCIH1876	CCLE Cell Line Gene CNV Profiles	1.0	2.09041
LXFL529	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.44213
GTEX-P4PP-2426-SM-3P61L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.848839
GSE246911,GSE246913_4_v_1_arid1a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
PMC9675280-12950_2022_317_MOESM2_ESM.xlsx-LPS_vs_control-Unnamed_1_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K98061177	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31167
BRD-K55104181	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16773
outer SZ in dorsomedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15281
Field CA2, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09859
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08049
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.880877
GSE217452_3_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K37971917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95884
GSE206516,GSE206518_1_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300741
medial portion of STH	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.918223
THAP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG5-0826-SM-2I5GF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45989
IM95_STOMACH	CCLE Cell Line Proteomics	1.0	5.49538
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-A54E-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35625946	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08012
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RTLS-1126-SM-46MUQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954704
H3K36me3_cardiac mesoderm_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE254517_1_v_0_irf7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.767018
BRD-K07368164	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7757
GSE205316,GSE205317_0_v_1_nrip1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE214596,GSE214598_1_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K61590534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3257
r8 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.37743
HD-26-KX74_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.597237
GSE139540_0_v_2_menadione_human	RummaGEO Drug Perturbation Signatures	1.0	null
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08104
gata3_21892208_mda_mb_231_gof_human_gpl570_gds4080	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.15427
rhombomere 10	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06188
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE190186,GSE190188_8_v_5_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.30937
HNF4G	ENCODE Transcription Factor Targets	1.0	null
BRD-K94881465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21186
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.97229
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1239
deferoxamine-mesylate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38598
BRD-K63761383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44604
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07106
GSE143994_2_v_3_ythdf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE169155_5_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
3329_GDF15_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.883452
Breast	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17828
BRD-K41206520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05111
GSE239578_5_v_7_cxadr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETV6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.2355
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.979329
BRD-K98153780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28552
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.42008
H3K4me1_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K92640680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44012
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3194-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
Brain Lower Grade Glioma_LGG_TCGA-E1-A7YD-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE138019_4_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A57536034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22328
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
Medulla, sensory related	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09095
GSE201217_3_v_1_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AN3 CA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.862772
GTEX-XOTO-0011-R1B-SM-4B65C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00848
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16095
LD-69-ZV56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.20465
Brain Lower Grade Glioma_LGG_TCGA-DU-7309-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158834_0_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.44174
GSE113267_3_v_2_rfx7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r8 part of basointermediate reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00387
orbital frontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.52933
outer portion of lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.03477
BRD-K71501826	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06423
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DGKK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.33127
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53875
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE239844_11_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
enzalutamide_homo sapiens_gpl570_gse44905	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HEY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.955795
CEBPB	ENCODE Transcription Factor Targets	1.0	null
USF1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EOMES-20176728-TSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
BRD-K47326075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18181
PMC3296722-pone.0032481.s009.xlsx-Sheet_1_MSC_vs_references-Gene_Symbol_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XUZC-1626-SM-4BRVP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51492
GTEX-X4XY-1626-SM-46MVN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46591
7185_RBM8A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.507456
organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.917376
HCC2885	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.77584
RTN4R	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21809
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Septate junction	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.604
CCND1-20090754-RETINA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
22RV1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.18651
BRD-K43292469	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32145
GSE206342_1_v_0_kpna2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RIPK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30821
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A852-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE198165,GSE198166_8_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE216274,GSE216292_4_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FB-66-UU47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.401412
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7884719-41598_2021_83348_MOESM3_ESM.xlsx-male_port-EGR1_EGR1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24205
hsa-miR-548ae	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76754
CE-39-DG56_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.227235
Tonsil	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Arnt	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.65
GSE196699_2_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
claustrum, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.04701
POLR2AphosphoS5_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K44141416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2916
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HNF1A-27111144-CD8+TCELLS-MOUSE-BLOOD-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
SCC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31724
hsa-miR-514b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
dorsolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.68567
TAF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24694
VIIIB, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.04006
BRD-K13119652	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40537
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SF539	BioGPS Cell Line Gene Expression Profiles	1.0	1.1569
GSE139966_5_v_3_figla_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K93590856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25387
BRD-K00976973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5083
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.62634
regulation of organelle assembly	GO Biological Process Annotations 2023	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K07489055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.66239
BRD-K30992744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80474
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	1.0	3.76969
H3K27me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:G23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.0389
GSE186810,GSE186813_7_v_0_furin_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SW626	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.18105
GSE153757,GSE153758_1_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TTC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35869
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75041300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68213
GSE139966_4_v_0_figla_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_10_ZZZ3_ChIP-seq_in_shNT-Genebody_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-940	TargetScan Predicted Conserved microRNA Targets	1.0	0.056784
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.10232
midbrain raphe nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.968666
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OC-314	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.13908
GTEX-NPJ8-1926-SM-3MJGB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847561
BRD-K17234088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04914
NACC1-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
testis_7e	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.98436
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.24494
GTF3C4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12839
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE144838_1_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ductal carcinoma in situ	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.08
EOMES-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_2_ZZZ3_occupied_genes-ATAC1_bound_genes_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226091,GSE226092_0_v_1_sall1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UMUC1	DepMap CRISPR Gene Dependency	1.0	3.25553
BRD-K65005459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06827
GTEX-XGQ4-1526-SM-4AT6H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958759
GSE203485_1_v_0_sunitinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K79179851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24
BRD-K11925125	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14183
EM2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.92027
amygdalo-striatal transition	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67743
H4K5ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K36me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-632	TargetScan Predicted Conserved microRNA Targets	1.0	0.131849
Hypothalamus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.95931
PECAPJ49	DepMap CRISPR Gene Dependency	1.0	2.53425
GSE160817_0_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
TP53-16413492-CHIP-PET-HCT116-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.58456
Globus pallidus, internal segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13648
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-34a	TargetScan Predicted Conserved microRNA Targets	1.0	0.265648
hsa-miR-939	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
BRD-K34957967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05436
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-RC-A7SH-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EW-16	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.25529
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.93
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1549_KO_Rpl23a_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.55084
GSE207787_3_v_2_pdha1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.951243
EGR1	ENCODE Transcription Factor Targets	1.0	null
GSE111247_2_v_13_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-128	TargetScan Predicted Conserved microRNA Targets	1.0	0.140752
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.66591
DB-41-IH69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310604
intercalated amygdaloid nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.81649
OE-31-YC41_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.314939
NFE2L2_Mutation_GDS4498_597_mouse_Skin	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
Nuclear lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
Liver hepatocellular carcinoma_LIHC_TCGA-KR-A7K7-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.65466
BRD-K78747341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20649
III, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.13153
External cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76754
BRD-K31503053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32657
GTEX-QDVN-0626-SM-2I3FP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43583
BRD-K61354976	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7892
GSE148066,GSE157787_5_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE154767_2_v_5_adam10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SA-32-CC58_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296126
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.77112
PPARG	ChEA Transcription Factor Targets	1.0	null
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5589-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.980925
NOS-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.46764
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23441
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A902-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1285	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
orbital frontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08432
BRD-K90049800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40556
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.32799
ARID3A	ENCODE Transcription Factor Targets	1.0	null
GSE132948,GSE132949_2_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AC-36-SY22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.512987
H3K79me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SJXC-0426-SM-2XCFH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923945
FOXO1-23066095-LIVER-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.10343
BRD-K70851916	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59798
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34804325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12848
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
testis_7f	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.17084
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997954
WT1-25993318-PODOCYTE-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K36176133	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13393
GSE169205_4_v_7_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
USF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.63165
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.36314
BRD-K81982648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.12587
RCL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.96294
SIN3A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-N87	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17013
AA-86-YY62_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.403605
GTEX-RWSA-1426-SM-47JXA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.07023
BRD-K93153656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73817
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K10089296	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37345
PMC4595011-pgen.1005555.s003.xlsx-BPTF_UP-regulated-Ensembl_gene_id_BPTF	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95479169	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08367
pancreas	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.18672
Prostate adenocarcinoma_PRAD_TCGA-XJ-A9DX-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cyproheptadine-2021	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
EGI1	DepMap CRISPR Gene Dependency	1.0	3.56109
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Iloprost	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.29
Lung squamous cell carcinoma_LUSC_TCGA-85-7696-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary visual cortex (striate cortex, area V1/17)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.38363
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148692,GSE148695_2_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RD	GDSC Cell Line Gene Expression Profiles	1.0	2.23998
Kidney	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	2.2603
GSE195503_1_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K89423851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06936
GSE173810_4_v_6_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN017_MCF10A.WT.HP_24H:K16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.11133
Fluconazole	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.27
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-XBED-2626-SM-4E3J5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930126
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H2405	GDSC Cell Line Gene Expression Profiles	-1.0	-2.38978
Lung adenocarcinoma_LUAD_TCGA-50-6594-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
MM77	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80263
GTEX-WI4N-1126-SM-3LK7Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25914
hsa-miR-513c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3910	TargetScan Predicted Conserved microRNA Targets	1.0	0.047969
BRD-K24700188	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6794
DF-70-CD57_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214155
BT-474	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24031
Acute Myeloid Leukemia_LAML_TCGA-AB-2975-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7429-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6933-11A-01R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
t47d	HPA Cell Line Gene Expression Profiles	1.0	0.957759
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AR-19668381-PC3-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE140322_3_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
AB-18-YN11_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.4387
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_G1E-ER4_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H716	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.01722
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.92683
GSE188382_4_v_0_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GATA3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1	ENCODE Transcription Factor Targets	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.01532
Adrenal Gland	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.662835
mantle zone of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2183
DMD_Deficiency_GDS2996_614_mouse_Cardiac muscles from 10.5-month (mdx animals)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
medial nucleus of pulvinar	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23023
BRD-K56415410	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50168
BRD-K81543095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00845
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.31264
NRL_Deficiency_GDS1693_238_mouse_Photoreceptors cells of retinas at P10	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.125
hsa-miR-942	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.83707
Cytotrophoblastic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.948
BRD-K07281036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58797
Brain - Caudate (basal ganglia)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.05119
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.514265
NCI-H1437	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.57815
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
G142	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.19444
laudanosine-1741	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tubulobulbar complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.29639
Perturb_1505_KO_Tnfaip3_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.01402
GSE226249_5_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K56057104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39498
outer CP in subgenual (subcallosal) cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39178
FB-66-UU47_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225547
mecamylamine-7023	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ME1	CCLE Cell Line Gene CNV Profiles	-1.0	-2.7071
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.07398
Head and Neck squamous cell carcinoma_HNSC_TCGA-KU-A6H7-06A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-0011-R4B-SM-4AT5C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39166
BRD-K99939253	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07669
BRD-K93755725	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51949
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H7-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
ABL1_mutant_179_GSE45452	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.59608
Crus I, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.890067
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11067031-pnas.2317690121.sd03.xlsx-gene_list_-_2022-04-13T081711_1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_mouse_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158834_7_v_13_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15578
BRD-A71001587	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08685
GSE198982,GSE198986_1_v_2_daunorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.845218
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.48081
GSE133683_1_v_5_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HNF4G	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	25.5257
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830236
6845_PSMA5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.799693
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17324
Penis_Foreskin_Melanocyte_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.40633
SARS-dORF6_96Hour_23935999_GSE47960	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	1.60026
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HEXIM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09561
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211989_0_v_1_nlrc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157594_6_v_2_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19091
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4288	TargetScan Predicted Conserved microRNA Targets	1.0	0.159923
POU2F2	ENCODE Transcription Factor Targets	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6496-01A-11R-1789-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.839476
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92988
BRD-K49866832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08588
ATP2A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.37442
RD	DepMap CRISPR Gene Dependency	1.0	2.58734
BRD-K69074358	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21012
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.933306
PC14_LUNG	CCLE Cell Line Proteomics	1.0	2.68282
NCI-H2342	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972718
BRD-A39900448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27858
hsa-miR-34c-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
BRD-K27058632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09608
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.942771
BRD-K72685049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.01891
Prostate adenocarcinoma_PRAD_TCGA-YL-A8SQ-01B-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1954	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.86253
PANC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869312
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.16129
GSE144115_2_v_3_stag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00554
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.902616
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60846
CD71+_EarlyErythroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.16404
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
INPP5E	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.204
MKN-74	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.34153
BRD-K64571715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35157
CREB1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11426526-ppat.1012555.s014.xlsx-DEG_DC_Jurkat_LPS_vs_DC_JK-Unnamed_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.61323
GSE209601_0_v_1_mef2a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.911607
GSE174406_2_v_1_lin28b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THP-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.86087
SW982	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.44587
Bladder Urothelial Carcinoma_BLCA_TCGA-ZF-AA4N-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-1245b-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXB2::ELK1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.3777
GSE159937_1_v_0_tfcp2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
disopyramide-7035	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K09328667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2192
PMC12575911-43556_2025_329_MOESM2_ESM.xlsx-SD2_MITF_CoBindingGenes-Gene_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
ZNF85	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.1644
Icotinib	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.46
inferolateral temporal cortex (area TEv, area 20)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.992689
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF4A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MHH-ES-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.27783
Fallopian Tube	GTEx Tissue Gene Expression Profiles 2023	1.0	2.55403
skeletal muscle	HPA Tissue Protein Expression Profiles	-1.0	-0.845141
male reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
nucleolus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
GSE139455_4_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
VN(H5N1)_12hour_None_GSE37245	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.01734
rhombomere 9	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14911
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869312
ASXL1-24218140-BMDM-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE168797_1_v_5_cannabidiol_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-P44H-0011-R1A-SM-3NM8J	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864506
fallopiantube_8b	HPA Tissue Sample Gene Expression Profiles	1.0	1.03598
GSE146982_4_v_1_gpd1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posterior hypothalamic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.982618
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.00429
hsa-miR-1297	TargetScan Predicted Conserved microRNA Targets	1.0	0.436802
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02724
IRF1	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-8073-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4712-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
NAMALWA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE195559_0_v_9_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SW 1990	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.93219
BRD-K82578220	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09839
GSE248883_0_v_1_shmt2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLF5	JASPAR Predicted Transcription Factor Targets	1.0	null
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.40688
SKES1	CCLE Cell Line Gene Expression Profiles	1.0	1.50825
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.23
HB-75-KT12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291927
GSE180185_4_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Malpighian tubule	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.515
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EH-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.71551
GTEX-S7SF-1426-SM-4AT5A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20987
PRDM5	ChEA Transcription Factor Targets	1.0	null
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.06686
GSE144838_4_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K92172862	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96411
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE166169_0_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18961
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.935533
Seminal vesicle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869312
H3K9me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal male genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
superficial stratum of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19091
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4427
PrefrontalCortex	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16332
MRGBP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.17353
HCC1395	GDSC Cell Line Gene Expression Profiles	-1.0	-1.78827
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ChIP_SOX2_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FE-31-JU80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.251939
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SJXC-0726-SM-2XCFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830478
EP300_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63964208	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7453
ventrolateral prefrontal cortex_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.948507
RKO	CCLE Cell Line Gene CNV Profiles	1.0	1.92444
PMC6538380-elife-42374-supp3.xlsx-human-sp-ENSG00000007866_TEAD3	Rummagene Transcription Factor Associations 2026	1.0	null
ChIP_NACC1_18358816	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K21996934	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01847
Upper respiratory tract disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.29
UACC257	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.43694
FAM204A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40612
GTEX-U3ZM-0008-SM-4DXTQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.831917
H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HT1376_URINARY_TRACT	CCLE Cell Line Proteomics	1.0	6.01932
GSE198165,GSE198166_9_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JD-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH1581	CCLE Cell Line Gene CNV Profiles	-1.0	-1.47899
ChIP_SMAD1_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE132759_4_v_2_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K18346873	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10698
GSE206516,GSE206518_0_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.23427
5205_MRPL21_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.607409
TEAD4	ENCODE Transcription Factor Targets	1.0	null
CHP134	DepMap CRISPR Gene Dependency	1.0	2.26369
BRD-K26423054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75287
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112761,GSE112767_4_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.15615
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF	ChEA Transcription Factor Targets	1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46897949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.161
Prostate adenocarcinoma_PRAD_TCGA-HC-7740-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MA-17-XU09_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.233723
mantle zone of r8Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45643
SOX2-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.35043
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5877-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-527	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
BRD-K03470412	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22513
GSE253056_0_v_1_erythropoietin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2-21211035-LN229-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K56915252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41276
BF-27-HP68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.279068
SMRT-22465074-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K10541973	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2488
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Nearest_Ensembl_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QDVJ-1126-SM-48U1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51104
MC-40-IP75_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.32661
primary somatosensory cortex (area S1, areas 3,1,2)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.994719
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K67458784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19279
mantle zone of r9Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41392
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K69035249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.04286
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stratum lacunosum-moleculare of rostral CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.847646
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.909969
6615_PPDPF_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.705453
NUAK2	Kinase Library Serine Threonine Kinome Atlas	1.0	null
SIN3B	ChEA Transcription Factor Targets	1.0	null
A-427	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.42096
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99413603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.76896
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YT-1626-SM-32PK6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1444
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-CS-6669-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77940693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.83597
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.2096
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A1BL-01A-11R-A13Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DDIT3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.19021
Vesicle-mediated transport	Reactome Pathways 2024	1.0	null
GSE124410_2_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GRM	CCLE Cell Line Gene Expression Profiles	1.0	1.65199
Prostate adenocarcinoma_PRAD_TCGA-VP-A87D-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K65314728	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76292
CAKI-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE113267_0_v_1_rfx7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K96258717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64727
16872506-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GTEX-XQ3S-1726-SM-4BOOD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01165
SW1116	CCLE Cell Line Gene CNV Profiles	1.0	2.16487
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.486975
GSE112860_0_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VCAP_PROSTATE	CCLE Cell Line Proteomics	1.0	5.54972
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.458701
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE185519_3_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K81916372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05595
thyroid	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-1.61123
EP300_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL6-27268052-CHIP-SEQ-BCELLS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56013842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04613
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.79211
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE236003_1_v_3_ubr5_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A	ENCODE Transcription Factor Targets	1.0	null
CCND1	ChEA Transcription Factor Targets	1.0	null
HUVEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	2.28272
POU5F1-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K79267333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47258
TAL1_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.17366
ATF3	ENCODE Transcription Factor Targets	1.0	null
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.29
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7059-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC10928104-41419_2024_6576_MOESM4_ESM.xlsx-S14-FOXM1_targets_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
NANOG-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC10061014-Table5.XLSX-C_vs_LD-Table_S5c_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_DEX_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
TP53-16413492-HCT116-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
CRCGN013_HEPG2_24H:M06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.13007
DU-4475	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.35442
GTEX-QESD-0526-SM-2I5G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14648
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.43426
GSE246053_1_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAVER1	DepMap CRISPR Gene Dependency	1.0	4.14773
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.907462
CRCGN008_HEPG2_24H:C21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.0021
UWB1.289	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.65396
Perturb_12713_KD_KMT2D_SRP062172	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.19295
kidney	GTEx Tissue Gene Expression Profiles	1.0	1.35522
Basolateral amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.54103
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.17644
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE124097_3_v_0_trem2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K75192396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12232
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00073
GSE242199_9_v_5_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NT5C2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.20487
PRDM9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	161.272
17761949-TableS1	GeneSigDB Published Gene Signatures	1.0	null
BRD-K40894545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.292
FOS::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.0867
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
VMRCLCP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.4822
AR	ChEA Transcription Factor Targets	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-0126-SM-4BOP7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.928193
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.363
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67786
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.930338
BRD-K96671994	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03259
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE182680,GSE182683_5_v_9_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13561
BT20	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.83063
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.28293
GSE148066,GSE157787_2_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA2	ChEA Transcription Factor Targets	1.0	null
SW948_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	5.33673
PBX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.1604
supramammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75547
H3K36me3_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3913
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28134
HCC1500	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.996807
GSE158197_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210101,GSE210114_7_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
r10 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.11783
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39999
GTEX-VJWN-0126-SM-3GIK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.98374
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14914
BRD-K06203932	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27717
GSE203158_5_v_15_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
L-1236	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.14462
mantle zone of r9Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76754
GSE216540_1_v_6_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K33503286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59481
GATA2	ENCODE Transcription Factor Targets	1.0	null
BRD-K33122655	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00085
USF1_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCOR1	ENCODE Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.2722
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RPMI 8226	BioGPS Cell Line Gene Expression Profiles	1.0	1.75376
Lung adenocarcinoma_LUAD_TCGA-95-7947-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5J7-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOUAI	DepMap CRISPR Gene Dependency	1.0	2.37403
Lung squamous cell carcinoma_LUSC_TCGA-43-7658-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AD-16-HL96_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.47319
medullary hindbrain (medulla)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04053
regulation of hydrolase activity	GO Biological Process Annotations 2015	1.0	null
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.914987
GSE229344_2_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE206870,GSE206872_4_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MZ in posterodorsal (superior) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11111
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE199255,GSE199356_4_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3EO-11A-13R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE241701_2_v_3_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BC-40-TU13_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.81947
blood	GTEx Tissue Gene Expression Profiles	-1.0	-1.16793
GTEX-OIZH-0626-SM-3NB1L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836434
GTEX-QMRM-0726-SM-2I5G8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96142
TCF3-18347094-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
PMC6138639-41467_2018_6247_MOESM4_ESM.xlsx-S1_10_ZZZ3_ChIP-seq_in_shNT-Nearest_TSS_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149124,GSE149128_2_v_1_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138939_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
lateral hypothalamic area, mammillary region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.84132
GSE169205_0_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K26941844	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27039
SU8686	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48771
GSE206870,GSE206872_0_v_2_ascl1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08613
Perturb_2935_OE_Azin1_SRP237952	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Allergic rhinitis	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.29
PRDM5-23873026-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-OXRN-2426-SM-2I5EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15485
S1P_Deficiency_GDS3654_521_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
MAX_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82910696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38798
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
FD-06-CV80_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.242609
BRD-K89863047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.84022
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX2-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K20951097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33506
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5587-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K68663367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91318
liver	HPA Tissue Protein Expression Profiles	-1.0	-0.845141
lateropallial amygdalopiriform area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.42507
MCM10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06316
HPAFII	DepMap CRISPR Gene Dependency	1.0	2.417
GSE119564_1_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K43205312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57044
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of cilium assembly	GO Biological Process Annotations 2015	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMMY-0426-SM-33HBB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8957
BRD-K07526417	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30862
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
hsa-miR-3180-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-6846-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.29
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR0B1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC9022281-12967_2022_3377_MOESM1_ESM.xlsx-Table_S13-Table_S13_MR_resluts_of_brain_pQTL_and_large-artery_atherosclerotic_stroke_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-WY-A85E-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K66287173	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0042
GSE193402_0_v_4_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-760	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CHCA	DeepCoverMOA Drug Mechanisms of Action	1.0	0.35
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
NRF2-31884422-A549-HUMAN-LUNG-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-P44H-0426-SM-2XCEZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34044
GSE226316_11_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978431
hsa-miR-4300	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.0155
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.22807
hsa-miR-4747-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961633
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.2571
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.982462
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
liver_a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.5595
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32206
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.586732
GSE140997_4_v_7_nsun6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CALU-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.997954
MCF 10A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.835424
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Fetal_Intestine_Small	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.980117
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50216418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64253
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RN64-1626-SM-48FD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57367
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZMIZ1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
kidney_d	HPA Tissue Sample Gene Expression Profiles	1.0	1.64998
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858073
hsa-miR-149	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
GSE111035,GSE111040_8_v_5_plag1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN015_MCF10A.WT.HP_24H:P03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07601
PMC12271601-mmc2.xlsx-OUT_cells_03-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
NC-35-BF58_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.239641
hsa-miR-671-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.888902
hsa-miR-4254	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
PRDM5-23873026-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
glafenine-7018	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11133462-41467_2024_47218_MOESM5_ESM.xlsx-IL-10_SBNO2_KD-symbol_AR	Rummagene Transcription Factor Associations 2026	1.0	null
USF2_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18601936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11836
TTI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1887
PML	ENCODE Transcription Factor Targets	1.0	null
GSE190186,GSE190188_0_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SA-32-CC58_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.404378
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.30708
GSE169205_0_v_1_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27636
Cervix - Endocervix	GTEx Tissue Gene Expression Profiles 2023	1.0	2.41968
ATF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92825272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17705
PMC8190596-mmc2.xlsx-RUNX1_mut-RUNX1_mut_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K06614664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12192
FOXO1-23066095-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K88189489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18675
GSE167886_2_v_0_chd7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-30-SX80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.275028
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4A-Supplemental_Table_S4A_Differentially_expressed_genes_upon_ZFX_Knock_down_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8983
Brain Lower Grade Glioma_LGG_TCGA-HT-7873-01B-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K18128277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01879
HUNK_knockout_240_GSE14226	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.3914
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2574
GSE103122_0_v_1_puromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HNF4G_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06791
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23002
SETDB1	ENCODE Transcription Factor Targets	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K87205390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04776
GSE183413_1_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228639
GATA1	ChEA Transcription Factor Targets	1.0	null
Perturb_10282_KO_Phpt1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.2408
superficial stratum of r10Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45643
15869706-TableS2	GeneSigDB Published Gene Signatures	1.0	null
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.76777
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
POLR2AphosphoS5_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5451-11A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
7492_RPP38_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.743403
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050953
YA-92-YO01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.210895
ventrolateral prefrontal cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.91277
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MZ in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.38778
BB-84-DG64_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.499077
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92248
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE239844_6_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXP2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.158
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A46950333	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70752
NR0B1	ChEA Transcription Factor Targets	1.0	null
TAL1_megakaryocyte_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.982823
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999002
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-2926-SM-3LK82	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13535
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.21947
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.952966
GSE148066,GSE157787_9_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909798
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73G-01A-22R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.16634
BRD-K77290793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55
496100406_HIP_no dementia_no TBI_78_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.35558
GSE154577_13_v_5_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-WB-A80L-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of r7Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76754
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45582
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K55518911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5139
ChIP_POU5F1_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE253795_1_v_0_alkbh5_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PRDM14	ChEA Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A59X-01A-11R-A29R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.28295
thyroid_5c	HPA Tissue Sample Gene Expression Profiles	1.0	1.76324
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE225656_2_v_3_tsc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
STAT5A-24692510-EPITHELIUM-MOUSE-MAMMARY	ChEA Transcription Factor Targets 2022	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.4708
CA-72-JV60_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297337
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
EZH2	ENCODE Transcription Factor Targets	1.0	null
Intercalated amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51009
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.51278
SIN3A	ChEA Transcription Factor Targets	1.0	null
HDL cholesterol levels	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.939794
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TE-8	GDSC Cell Line Gene Expression Profiles	1.0	3.03258
BRD-K69521416	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13704
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50726
Perturb_11420_KD_TMEFF2_SRP302700	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
Perturb_3759_KD_VPS28_SRP325061	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.44588
Tamibarotene	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.26
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC5651844-41467_2017_1173_MOESM7_ESM.xlsx-ZZZ3_ChIP-seq_peaks-Unnamed_6_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-eTable_38_Cis-instrument_Mendelian_randomizaion_screen_of_1_901_cortical_proteins_on_lifetime_smoking_behavior_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
496100478_HIP_dementia_TBI_86_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	3.35767
BRD-K49368687	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65258
cytoplasm	LOCATE Predicted Protein Localization Annotations	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.908171
BRD-A64153357	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00708
regulation of cell projection organization	GO Biological Process Annotations 2015	1.0	null
central amygdaloid nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.87843
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.868286
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149124,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AA-70-VU13_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310844
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195503_3_v_2_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
regulation of cilium assembly	GO Biological Process Annotations 2025	1.0	null
PMC3435504-msb201237-s2.xls-Supp_Table_4b-SP1_SP1	Rummagene Transcription Factor Associations 2026	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5678-11A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-MF-A522-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE171486_4_v_0_ddx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SR 11237	DeepCoverMOA Drug Mechanisms of Action	-1.0	-0.3
Salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SNU1214	CCLE Cell Line Gene CNV Profiles	1.0	2.48675
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.519
USF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K90325960	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35389
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.893579
Nucleus x	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05726
LB771-HNC	GDSC Cell Line Gene Expression Profiles	-1.0	-2.92876
GTPase activator activity	GO Molecular Function Annotations 2023	1.0	null
GSE102870_3_v_9_nr1h4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62965
NRF1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RK-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE192663_1_v_5_acly_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GATA1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1774
GSE218879_1_v_2_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4270	TargetScan Predicted Conserved microRNA Targets	1.0	0.034317
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3187-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172020_0_v_2_testosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GABPA_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HLE	CCLE Cell Line Gene Expression Profiles	-1.0	-1.48731
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRAM1L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12207
GSE127790_13_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Breast carcinoma in situ	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.065
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
BRD-K33863933	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12351
BRD-K98876398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37806
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE186287_2_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199255,GSE199356_0_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139540_0_v_1_menadione_human	RummaGEO Drug Perturbation Signatures	1.0	null
GLA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.80692
r8 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19091
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.870132
HNF4A	JASPAR Predicted Transcription Factor Targets	1.0	null
Artery - Aorta	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.675631
intermediate stratum of LAP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.55772
FNTA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32731
EoL-1-cell	GDSC Cell Line Gene Expression Profiles	1.0	1.95811
SP1	ENCODE Transcription Factor Targets	1.0	null
BRD-A58803929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21491
GTEX-WH7G-1726-SM-4LVKY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918554
GSE229973_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN015_HEPG2_48H:E22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.33562
BC3C	CCLE Cell Line Gene CNV Profiles	1.0	1.34695
SOX17-20123909-XEN-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-O5YV-1026-SM-3LK72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.969735
enzyme activator activity	GO Molecular Function Annotations 2015	1.0	null
MEC1	DepMap CRISPR Gene Dependency	1.0	3.01875
MG63	DepMap CRISPR Gene Dependency	1.0	3.1069
GSE112761,GSE112767_2_v_0_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3657	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
3568_GTF2B_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.13854
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-QA-A7B7-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.040582
GSE193258,GSE193259_5_v_15_osimertinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN010_HEPG2_24H:H05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16562
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.03454
HEC251	CCLE Cell Line Gene Expression Profiles	-1.0	-1.747
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.34158
18400362-Figure4a	GeneSigDB Published Gene Signatures	1.0	null
GSE239844_11_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FE-64-KC49_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.24836
superficial stratum of r7Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3453
BRD-K19969409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54434
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RUNX1-22412390-EML-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-K18208847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25507
GSE199255,GSE199356_4_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN009_HEPG2_24H:G22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.40085
protein transport	GO Biological Process Annotations 2025	1.0	null
BRD-K20142115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48589
KYO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73614
HT-1376	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.95109
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K34798837	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12593
GTEX-SE5C-0726-SM-4BRWY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.896601
ASXL1-24218140-BMDM-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1	ENCODE Transcription Factor Targets	1.0	null
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fallopiantube_8d	HPA Tissue Sample Gene Expression Profiles	1.0	1.13909
kidney_c	HPA Tissue Sample Gene Expression Profiles	1.0	0.84981
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20101
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RMG-I	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20673
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-11A-01R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K21412601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05083
4-hydroxyphenazone-1915	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE136622_0_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.45643
GSE131798,GSE131804_2_v_0_igf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE162276_4_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC10319804-41467_2023_38747_MOESM10_ESM.xlsx-circARID1A_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
membrane-enclosed lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
BRD-K54836449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82643
BRD-K25844701	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12231
Brain Lower Grade Glioma_LGG_TCGA-DB-A4XE-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE228106_3_v_2_paclitaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66242
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1611
hsa-miR-1343	TargetScan Predicted Conserved microRNA Targets	1.0	0.140752
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.703421
osteoblasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.09872
BRD-K95935249	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47687
Perturb_8828_KD_DDX60L_SRP313537	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-5.88522
r9 part of parvocellular medial vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2183
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
WDR73	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00576
BRD-K61354849	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67292
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07106
BRD-K82112239	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20739
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.97181
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.229792
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7518873-abb0205_Table_S1.xls-TFEB_targets-ensembl_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WI4N-0726-SM-3TW93	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.857932
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.884121
Skin	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.933984
GSE144838_2_v_3_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COX7A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.40733
STAT1	ENCODE Transcription Factor Targets	1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7043-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Crus I, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.841763
enalapril-7428	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nuclear part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	0.233497
CRCGN014_HEPG2_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.16685
HCC1143	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.694152
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941807
cerebellum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.25851
hsa-miR-26a	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.08613
Allergic disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.29
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28316
SALL4	ChEA Transcription Factor Targets	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28856
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH522_LUNG	CCLE Cell Line Proteomics	1.0	2.07887
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.40719
GSK3B_knockdown_209_GSE35351	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.88057
ZBTB7A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K18515345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10911
GTEx Skin 20-29 vs 70-79	GTEx Tissue-Specific Aging Signatures	-1.0	-9.52332
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-67-3771-01A-01R-0946-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2228	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.05396
GSE111247_2_v_7_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
C-33 A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K07624584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59761
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWCY-2326-SM-2I3EQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996719
GSE77108_0_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K31577322	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12007
GSE221633_3_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE240027,GSE240030_1_v_4_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cingulate gyrus, frontal part, left, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.935931
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08745
BRD-K73183447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38671
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K36252987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08385
GSE149621_3_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20761
SIX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.297401
RFC3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11083
GSE77108_3_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.404326
U87	BioGPS Cell Line Gene Expression Profiles	1.0	0.988348
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K07009788	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42679
hsa-miR-770-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CRCGN013_HEPG2_24H:C24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.05369
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8961
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8489
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.38942
H3K4me1_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MFE280	CCLE Cell Line Gene CNV Profiles	1.0	1.82261
EIF1AY	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.31995
SCS214	DepMap CRISPR Gene Dependency	1.0	2.56814
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Common_KLF5_peaks-Gene_Name_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
area postrema	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51647
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
r9 part of external cuneate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04882
liver_d	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.27464
Hyaline fibromatosis syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.285
Uvula (IX)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23744
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.16805
H3K9me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CBX3_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11174
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
female reproductive gland	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE190384,GSE190386_3_v_4_fulvestrant_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.902697
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80228
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11953091-12035_2025_4695_MOESM1_ESM.xlsx-s5-Supplementary_Table_5_Results_of_the_2-sample_pQTL_MR_on_insomnia_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
PLIN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22841
CRCGN016_MCF10A.WT.HP_24H:K06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.3842
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84138
posteroventral (inferior) parietal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.07134
GSE153137,GSE153140_2_v_0_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE248858_5_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE125011_0_v_2_cd83_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.05954
ZBTB33_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NACC1-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16578
9656_USP39_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.519501
496100628_FWM_dementia_TBI_77_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.00025
parataenial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39116
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.940174
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE93674_2_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE98964_1_v_4_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.62565
GSE130383_2_v_3_gps2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.03948
PMC10746608-427_2023_709_MOESM4_ESM.xlsx-MITF_Targets_enrichment-Unnamed_137_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_5231_KO_Kmt5c_SRP194976	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Prostate adenocarcinoma_PRAD_TCGA-HC-A48F-01A-11R-A250-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31666794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59512
GTEX-S341-0126-SM-4AD64	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978909
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Primary somatosensory area, barrel field, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21698
GSE140322_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE164757,GSE164759_1_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
DB-41-IH69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.518402
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4700-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GTEX-P78B-0008-SM-48TE1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35054
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52431
GSE97278,GSE97280_2_v_1_nsd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH2052	DepMap CRISPR Gene Dependency	1.0	2.1965
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.999002
2893_TAFA2_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.610829
cerebellar cortex_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13443
BRD-K89952634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64207
BRD-K90519599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.27308
NB-58-SA13_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.217013
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15302
GSE223008_9_v_2_calhm6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE145323,GSE145324_1_v_4_rfx3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-6011-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
GSE105170,GSE105175_1_v_0_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
Uterine cervix	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
PRRX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.6281
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E7-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-4643	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
ALVA31	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.058
GTEX-RNOR-0011-R4A-SM-3GAD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27097
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37224
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.52249
GSE158197_2_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.665
NCI-H2461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21753
GSE160817_5_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K12015168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20868
CHD2	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6430_KD_FUBP1_SRP110582	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.11439
BRD-K46322281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62199
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221544
ILF3_02_94	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59241
TCF3-18692474-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874924
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.81563
r7 part of spinal trigeminal nucleus, interpolar part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3453
GSE114992,GSE114993_7_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
BRD-A85216385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91475
BRD-K97462883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08772
PMC7518873-abb0205_Table_S1.xls-TFEB_targets-symbol_TFEB	Rummagene Transcription Factor Associations 2026	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DB-5279-01A-03R-2347-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
ATF3_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199204,GSE211619_4_v_6_glutamine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-S4P3-0226-SM-3K2BD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83099
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.915162
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.82737
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_431_KD_MYBL2_SRP371675	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.0393
CAKI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49573
Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of metabolic process	GO Biological Process Annotations 2015	1.0	null
TECR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00603
GSE184884_4_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE234514,GSE234516_2_v_0_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199255,GSE199356_3_v_2_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-3196	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
FF-90-JK74_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.232705
DAN-G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.3361
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.865024
JHESOAD1	DepMap CRISPR Gene Dependency	1.0	2.3642
hsa-miR-124	TargetScan Predicted Conserved microRNA Targets	1.0	0.145356
GSE148066,GSE157787_0_v_10_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.08868
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_12992_KD_MAFB_SRP276044	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.31768
GSE158834_7_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K24496049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2422
BRD-K81370109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84185
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA2_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEL-HO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.49694
KAP1-27257070-CHIP-SEQ-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Breast apocrine carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.584
A498	CCLE Cell Line Gene Expression Profiles	1.0	1.4851
lateral ventricle	HPA Tissue Protein Expression Profiles	-1.0	-0.845141
PU.1	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K58756877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70609
GSE203308_14_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE163884_1_v_0_sumo2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE147876,GSE147877_4_v_6_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119345_0_v_3_bexarotene_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H2172	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13585
MLLT6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18631
BRD-K59587063	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60466
PMC11195603-jamapsychiatry-e241429-s002.xlsx-eT38_Protein_cis-instrument_MR-Unnamed_2_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_10283_KO_Selenbp1_ERP017365	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.16384
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-Vietnam-1203-2004(H5N1)_24Hour_21865398_GSE28166	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.04308
GTEX-S341-0726-SM-4AD5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18197
striatal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68266
C-33-A	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.6225
VI, left, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.880453
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
3291_GATA1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.541753
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-1426-SM-3DB8Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.966424
Field CA3, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36814
M059J	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40752
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7046-11A-01R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_DLX3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CRCGN016_MCF10A.TP53.M_24H:B11	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1451
BRD-K21420222	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33591
Perturb_4844_KO_Hoxd12_SRP307505	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.9326
BRD-K55142307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05464
CRCGN011_HEPG2_24H:B04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.12675
GTEX-WFG7-1826-SM-3GIL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15303
H3K9ac_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_13_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TRIB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07222
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
UACC-257	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.19519
Perturb_17043_KD_GORASP1_SRP201887	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
RPS10	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53915
FOXA1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1953
PPARG-20887899-3T3-L1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
TSTD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18069
Intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.714
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
ESET-19884257-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K03476091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17489
BRD-K39037393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.67495
Lung squamous cell carcinoma_LUSC_TCGA-96-A4JL-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DB-21-FY75_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.241549