association	dataset	threshold value	standardized value
BRD-K84790105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80971
propafenone-6336	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_10363_KD_Rorc_SRP185851	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.1581
GSE242290_3_v_11_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ME-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SPI1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CHRNB3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00501749
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QQ-01A-41R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE63048_11_v_12_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K81999794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11411
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03521
Preribosome	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
integument	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-K16047442	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66414
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K87419143	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11136
BD-69-GX17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.80473
NB-80-IM48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.3129
H3K27ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA1_G1E-ER4_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2291_OE_TBX3_SRP184219	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.28731
FUOV1	CCLE Cell Line Gene Expression Profiles	1.0	1.35477
skin	GTEx Tissue Gene Expression Profiles	1.0	0.872
Perturb_15266_KD_Csde1_SRP288392	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.77362
BRD-K28753508	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47
BHLHE40_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
imatinib_homo sapiens_gpl96_gds3046	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HSBP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00454
RUNX1	ChEA Transcription Factor Targets	1.0	null
NCIH28	CCLE Cell Line Gene Expression Profiles	-1.0	-1.84507
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.10617
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.25051
BRD-K25280080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44811
DCP1A	ChEA Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67S-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4841-01A-01R-1277-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1033_KO_Apoe_SRP197523	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.14039
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-VS-A8EJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NB13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NIHOVCAR3	CCLE Cell Line Gene CNV Profiles	1.0	2.29049
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TROVE2	Hub Proteins Protein-Protein Interactions	1.0	null
AB-92-GP61_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.221212
BL735 (TERF2IP)	NURSA Protein Complexes	1.0	null
PAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7893
biological_process	GO Biological Process Annotations 2015	1.0	null
GSE140607_3_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BL2762 (HNRNPU)	NURSA Protein Complexes	1.0	null
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201309_4_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LOX IMVI	BioGPS Cell Line Gene Expression Profiles	1.0	0.892831
CREB1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA1-22383799-G1ME-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
small-subunit processome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.23505
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-0003-SM-47JWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24204
GTEX-Q2AG-0626-SM-2S1PV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958296
JUND_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-0011-R4a-SM-2I3GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945064
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.943135
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32206
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
AHR	Pathway Commons Protein-Protein Interactions	1.0	null
MGE-Lateral region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53661
BL294 (RPRD2)	NURSA Protein Complexes	1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE191021_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	1.0	null
MTF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.4176
BRD-K70468140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88968
ESRRA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYC	ChEA Transcription Factor Targets	1.0	null
BRD-K19652835	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74974
Pallidum, medial region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16981
BL1244 (MAML3)	NURSA Protein Complexes	1.0	null
BL2125 (HDAC3)	NURSA Protein Complexes	1.0	null
2-deoxy-D-glucose-344	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
AMO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.86001
GSE247862,GSE247863_4_v_3_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2811-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer CP in caudal cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.960208
BRD-K50278697	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50246
TCF12_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Perturb_5792_KO_Gzma_SRP284215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.97802
GSE157296,GSE157298_4_v_5_kbtbd4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.03656
BRD-K28916436	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54289
NCI-H1876	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-O1-A52J-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169697,GSE169725_1_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SMARCB1	ENCODE Transcription Factor Targets	1.0	null
HCC1428	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.709391
Lung squamous cell carcinoma_LUSC_TCGA-18-3408-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RUSQ-0826-SM-47JWW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855447
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K08212599	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58512
DOK	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K47443098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7637
H3K4me1_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-A44B-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GTEX-S4UY-0526-SM-3K2AN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22506
NR2E3	Pathway Commons Protein-Protein Interactions	1.0	null
BA-39-HG26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.258224
quinisocaine-4791	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
liver cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.115295
TP63	ChEA Transcription Factor Targets	1.0	null
NCI-H146	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44548
2932_RIPOR1_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.646746
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Stroke	HuGE Navigator Gene-Phenotype Associations	1.0	null
BL2753 (LCOR)	NURSA Protein Complexes	1.0	null
r8 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23268
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CSTB_KO_GSE47516_18_mouse_brain (P7 cerebellum, P30 cerebellum, cerebellar granule cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
AD-18-XC14_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.232013
JJN3	CCLE Cell Line Gene Expression Profiles	1.0	1.51197
H3K9ac_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
OVK-18	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.12037
GCIY	CCLE Cell Line Gene CNV Profiles	1.0	1.41002
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13436
Perturb_14199_KD_GATA6_ERP108557	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.97481
GSE235701,GSE261434_2_v_1_enasidenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Loin	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.991
GSE227634,GSE228381_0_v_7_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MLL3/4 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.77
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00303
SUPT20H_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0011-R1A-SM-2I5GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.55081
BL4874 (FBXO11)	NURSA Protein Complexes	1.0	null
G-292_CLONE_A141B1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
cingulate gyrus, parietal part, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.932761
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64526
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A17043706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40162
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL8779 (SEPT9)	NURSA Protein Complexes	1.0	null
azaperone-5877	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4761-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.65871
HCC827	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828445
Testis	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.73649
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD34 Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
skin	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
MXI1_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL1111 (CENPF)	NURSA Protein Complexes	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-H9-A6BY-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193402_0_v_1_imatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UTP-C complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.63
H zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.048
inferolateral temporal cortex (area TEv, area 20)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09438
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A6H3-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAC3-21632823-H3396-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PMC6811834-sby183_suppl_supplementary_data_set_1.xls-ZNF804A_DEX_FDR_0_01-Gene_Symbol_ZNF804A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE114992,GSE114993_9_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SOX9	ChEA Transcription Factor Targets	1.0	null
GATA1_G1E-ER4_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PRPS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13484
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Genetic Predisposition to Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-92-8065-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2347	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.834484
USF1_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5832-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
H3K36me3_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle	LOCATE Curated Protein Localization Annotations	1.0	null
GSE165682_4_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20905
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CBC173 (AGAP3)	NURSA Protein Complexes	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A4F4-06A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BL2757 (CRABP2)	NURSA Protein Complexes	1.0	null
BRD-K11782435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7912
Lateral ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
Perturb_9725_OE_PCX_SRP255647	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	11.3809
BL1036 (KDM1)	NURSA Protein Complexes	1.0	null
BRD-K12011077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21211
lung	HPA Tissue Protein Expression Profiles	-1.0	-1.04297
H3K27ac_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A39X-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K02637850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59606
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K91470977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20391
RFC1	Hub Proteins Protein-Protein Interactions	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03959
AA-58-FJ71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.569116
BRD-K07350528	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32954
GSE112760,GSE112767_2_v_5_ddx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A8HY-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC2752535__F4	PFOCR Pathway Figure Associations 2024	1.0	null
GSE209582_1_v_0_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Depression_Cerebral cortex_GSE12654	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.79546
BRD-K45044525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55222
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.69424
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ATF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K14081852	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.15558
BRD-K02530287	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39318
RF-36-EI47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.326738
ATF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-5	GDSC Cell Line Gene Expression Profiles	-1.0	-1.92062
RXRA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-1026-SM-33HBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20269
CTCF_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC-15	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869499
BRD-K09395335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33811
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A7UI-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-JW-A852-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T6MN-0126-SM-32PLP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20912
intermediate stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1563
Central nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.273
Lung squamous cell carcinoma_LUSC_TCGA-56-8624-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF767	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.05267
FOSL2_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QGP1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.49798
ventromedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.22422
COLO 794	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.962291
LD-48-CY61_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211273
posterior (caudal) superior temporal cortex (area 22c)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.6055
testis_7f	HPA Tissue Sample Gene Expression Profiles	1.0	1.54527
BRD-K34498495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14994
tretinoin-1548	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
plant form	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.256568
FOXP1	ChEA Transcription Factor Targets	1.0	null
Perturb_3958_KO_GSDMB_SRP350967	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.12399
BRD-K13852343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88312
BRD-K40674409	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.1663
GSE148321,GSE169423_2_v_1_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE136622_2_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
doxorubicin_homo sapiens_gpl6947_gse25741	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HEC-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.39163
intermediate stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23219
GSE227891_5_v_3_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29723
Lung adenocarcinoma_LUAD_TCGA-55-7727-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
COV362	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.52255
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
posterior (caudal) superior temporal cortex (area 22c)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.897215
spleen	HPA Tissue Protein Expression Profiles	-1.0	-1.04297
DDX59	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40758
GSE233112_2_v_0_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
FA-80-DR66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.65163
CA4 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.04391
renal	GAD High Level Gene-Disease Associations	1.0	0.293278
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.831369
Perturb_15545_KD|KO_Pten|Tip5_SRP199649	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GSE200982_0_v_2_plac8_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R1a-SM-48TDJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95937
NCI-H2405	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.75472
ChIP_MYC_19079543	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.26845
GTEX-T6MO-1626-SM-32QOM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12047
GSE76771_1_v_3_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K19474742	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5355
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K87821938	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54681
FOS	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	23.6124
GSE199644_3_v_1_palmitic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
amygdaloid complex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.949664
OKAJIMA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00186
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
rostral migratory stream	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37789
GSE166004_3_v_2_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K15499806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35444
periventricular stratum of PcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3036
GTEX-NL4W-0011-R11A-SM-2I3DW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.954313
GATA1_G1E-ER4_mm9_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211177,GSE211178_9_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ED-05-LQ40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.58695
BL9238 (GREB1)	NURSA Protein Complexes	1.0	null
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_3733_KO_Trp53_SRP296860	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-10.8677
CAL148	CCLE Cell Line Gene CNV Profiles	1.0	1.39448
CA1 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.2583
GTEX-QESD-0626-SM-2I5G4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15716
GTEX-V1D1-2126-SM-4JBH4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.52528
Brain Lower Grade Glioma_LGG_TCGA-HT-A74K-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K53971345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06992
BRD-K22380647	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35762
HCFC1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXM1	ENCODE Transcription Factor Targets	1.0	null
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828445
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
E2F4	ChEA Transcription Factor Targets	1.0	null
HCC1395	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84697
HTC-C3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
medial habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.71498
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56943789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24694
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.859878
layer III of rostral entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.959616
GTEX-U3ZH-1526-SM-4DXV1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46525
CBC181 (BICD2)	NURSA Protein Complexes	1.0	null
Dehydration_CNS - Brain - Hypothalamus (MMHCC)_GSE4130	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.64205
GTEX-SIU8-0126-SM-2XCDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19244
HCT 116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.48219
CRCGN011_HEPG2_24H:O06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.35215
Acute Myeloid Leukemia_LAML_TCGA-AB-2856-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BL6494 (ESCO2)	NURSA Protein Complexes	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982467
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944055
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4829_KD_Rrp40_SRP150410	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.21766
EP300_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211177,GSE211178_0_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.837183
BHY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828445
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89864
BL892 (BLM)	NURSA Protein Complexes	1.0	null
GSE244072_4_v_6_tfeb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC1428	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.890322
CCDC86	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22626
trovafloxacin_homo sapiens_gpl96_gse9166	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LS 180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SKM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PMC9287735-mmc8.xlsx-MI_Related_Genes-TNF_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
Female pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.998
r9 part of nucleus gracilis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01638
BRD-K62372121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04791
CREB1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R5a-SM-2I3GB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41949
posteroventral (inferior) parietal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.976455
TAL1_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895805
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
heterocycle metabolic process	GO Biological Process Annotations 2015	1.0	null
intermediate stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12318
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Protoscolex	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.674
H3K4me3_CH12.LX_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
granular layer of rostral dentate gyrus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.76014
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AN-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
digestive gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053632
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-0126-SM-32PLI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946557
BRD-K30977850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.69171
SNU-216	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21904
MMP16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42761
superficial part of arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3483
NCI-H358	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
atropine-5865	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
C-33-A	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.44873
GSE142684_3_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KP4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15073
Prostate adenocarcinoma_PRAD_TCGA-HC-A6HX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RC3H2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36576
SFN	Hub Proteins Protein-Protein Interactions	1.0	null
GTEX-OXRO-1726-SM-3LK6C	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08166
superficial stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96896
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Anaplastic thyroid cancer cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.029
Dense fibrillar component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.461
GTEX-QEG4-0126-SM-48TZE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.87462
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MG-63	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06086
GTEX-NPJ8-2226-SM-3TW8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52729
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51K-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OCUM-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.937198
GSE227698_5_v_3_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CC-50-FK24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.2032
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB33	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPN-0011-R3A-SM-2I5FC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16928
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_6716_KD_NAA40_SRP308012	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.45607
GTEX-X4EP-0626-SM-3P621	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08721
SEC31A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06781
BRD-K59194147	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.0828
membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE86507,GSE86509_7_v_2_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.7439
astemizole-1365	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K07861364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19031
SF-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.916
GTEX-S7SE-0326-SM-4AT5Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97257
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.99711
HS633T	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K79me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K-562 cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	1.22195
GSE111385_0_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-TFDP1_TFDP1	Rummagene Transcription Factor Associations 2026	1.0	null
lateral group of nuclei, right, dorsal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.05891
BRD-K45952474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71335
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A6C6-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A17Z-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.09569
ETS1	ChEA Transcription Factor Targets	1.0	null
GSE136238_1_v_0_ebf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC202	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00303
GTEX-VUSG-0003-SM-3NMDK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.971041
homochlorcyclizine-7417	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
small-subunit processome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
POLR2A_GM10847_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nortriptyline-6003	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Granular component	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.437
Perturb_16836_KO_Lats1/Lats2_SRP119763	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.78037
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67715154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.351
BRD-K62226454	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35835
BRD-K99078335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.51799
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.457
POU2F2	ENCODE Transcription Factor Targets	1.0	null
membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
BL2843 (MED12)	NURSA Protein Complexes	1.0	null
PMC11761043-media-2.xls-r_0_3-CEBPZ_CEBPZ	Rummagene Transcription Factor Associations 2026	1.0	null
BL2263 (DOCK9)	NURSA Protein Complexes	1.0	null
GSE60837_6_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ5-1526-SM-3P5ZX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50838
nucleolar part	GO Cellular Component Annotations 2015	1.0	null
primary auditory cortex (core)_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.902225
GTEX-XQ3S-2726-SM-4BOP2	GTEx Tissue Sample Gene Expression Profiles	1.0	2.24477
testis_7a	HPA Tissue Sample Gene Expression Profiles	1.0	1.37277
BL2763 (HNRNPU)	NURSA Protein Complexes	1.0	null
POU2F2_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pregeniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39974
HCC1187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.1016
Bach1::Mafk	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.5702
central part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.04165
GSE217552_3_v_4_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RUNX1-27514584-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02269304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77362
PAX5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEF2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0011-R7A-SM-2TF5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1219
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A5BT-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K23704908	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43557
pirlindole-3140	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HCC364	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67644
TNPO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03731
maturation of ssu-rrna	GO Biological Process Annotations 2015	1.0	null
BRD-K54742099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59305
GSE209898,GSE209899_0_v_1_flcn_human	RummaGEO Gene Perturbation Signatures	-1.0	null
THG1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.58048
BRD-K27782186	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96352
GTEX-RTLS-0526-SM-2TF64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17075
BRD-K11577431	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63612
Perturb_7293_KD_U2AF35_SRP116787	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.93928
mantle zone of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02622
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDA-MB-231	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828445
lateral subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.02508
BL1657 (SMG1)	NURSA Protein Complexes	1.0	null
BRD-K08154407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36975
WDR33	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.28204
FOXC1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K07551625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29565
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ZBTB33_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL2127 (HDAC3)	NURSA Protein Complexes	1.0	null
BRD-K62147342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1633
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Neuro D	MotifMap Predicted Transcription Factor Targets	1.0	null
BRD-K91917132	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.55699
ZNF417	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.4124
PMC9270251-mmc2.xlsx-4_Filtered_DEGs_Control_vs_KD_3-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32194
primary metabolic process	GO Biological Process Annotations 2015	1.0	null
Perturb_4973_KO|KD_Kmt2d|Kdm1a_SRP107208	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.46979
SIRT7	Pathway Commons Protein-Protein Interactions	1.0	null
BL5844 (ZFC3H1)	NURSA Protein Complexes	1.0	null
BL1733 (SPEN)	NURSA Protein Complexes	1.0	null
GSE162276_5_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE169152_3_v_6_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC11749115-loae020_suppl_Supplementary_Table_S2.xlsx-CHOP-high-gene_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K18ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
fluphenazine-5234	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_3936_KD_MIR1290_SRP291996	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.58728
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ACHN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.54065
FA-63-WI26_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.53756
Perturb_8480_KD_CSDE1_SRP117243	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.21337
BXPC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-OXRO-0011-R10A-SM-2I5EH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.46539
clorgiline-3219	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
Saos-2	GDSC Cell Line Gene Expression Profiles	-1.0	-1.90175
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
KASUMI1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.71192
BRD-K14589361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10465
HUT78	CCLE Cell Line Gene CNV Profiles	-1.0	-1.50954
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K00667983	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17758
GSE195513_0_v_3_cpeb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	6.20024
Flower stalk	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.767
RXRA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PF-382	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYOG_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL7067 (IKBKB)	NURSA Protein Complexes	1.0	null
Fibrillar center	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.441
EP300_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE123002_0_v_1_srsf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
OVKATE	CCLE Cell Line Gene CNV Profiles	1.0	1.42795
WE-48-PP43_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.24365
GSE243491_1_v_2_oxaliplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BL3822 (JMJD1C)	NURSA Protein Complexes	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.923195
endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	GO Biological Process Annotations 2023	1.0	null
HCC1263	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869499
AC-28-RT00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.230027
GSE149903_0_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
EEF1B2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36832
superficial stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.30405
Aryl hydrocarbon receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.934
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
AB-71-CI37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.422521
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMK1-0001-SM-4B64F	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83055
PMC9314667-Table_1.xlsx-Regulons-FOSL1_FOSL1	Rummagene Transcription Factor Associations 2026	1.0	null
cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040843
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-3.38083
leaf	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.396465
lateral subdivision of area 9	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02174
GTEX-NL3H-0011-R11A-SM-2I3E6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.8347
VCAP	CCLE Cell Line Gene CNV Profiles	-1.0	-1.49713
Perturb_3949_KO_FURIN_SRP197346	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.20314
GTEX-OIZH-2026-SM-3NB1M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983676
GTEX-XMD1-0011-R1A-SM-4AT4C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19338
GTEX-XUZC-1626-SM-4BRVP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15458
adult retina	HPM Cell Type and Tissue Protein Expression Profiles	-1.0	-1.17459
BRD-K91469267	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07081
Proteasome regulatory particle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.672
DMS454	CCLE Cell Line Gene Expression Profiles	-1.0	-2.67485
GSE185519_4_v_5_gilteritinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XV7Q-1526-SM-4BRWB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.947992
GSE139427_2_v_1_ibrutinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8169803-mmc2.xlsx-KDM2B-GFP-Unnamed_1_KDM2B	Rummagene Transcription Factor Associations 2026	1.0	null
shell part of the anterobasal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00782
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K52859120	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12328
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RNA polymerase I complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.749
caudal prosubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44655
GSE116810_2_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K96776591	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07918
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.93437
EZH2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
caudal ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.24672
cellular_component	GO Cellular Component Annotations 2015	1.0	null
amygdalohippocampal transition zone, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.19947
GTEX-X4XY-0226-SM-4E3IZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2893
MXI1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EWS502	CCLE Cell Line Gene Expression Profiles	1.0	1.39707
small-subunit processome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.691
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX2-33478486-IMR90-HUMAN-LUNG	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29211
RL95-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K56119660	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75036
GSE160817_7_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
peduncular nucleus of the stria medullaris	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09693
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventromedial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61876
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02002
496100347_PCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.37957
BRD-K71716722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76648
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	GO Biological Process Annotations 2025	1.0	null
YY1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A119-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE81193_3_v_5_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC11985509-41467_2025_58704_MOESM7_ESM.xlsx-ZNF385A_vs_NLS-Unnamed_1_ZNF385A	Rummagene Transcription Factor Associations 2026	1.0	null
SEC63	Hub Proteins Protein-Protein Interactions	1.0	null
BL1573 (CDC2L6)	NURSA Protein Complexes	1.0	null
90S preribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.97
dexpanthenol-7455	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895805
5447_NADSYN1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.793414
BL531 (MCM10)	NURSA Protein Complexes	1.0	null
Perturb_1445_KO_Irf3/Irf7_SRP221603	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.24443
SPI1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	GO Biological Process Annotations 2023	1.0	null
HNF4	MotifMap Predicted Transcription Factor Targets	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5LA-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUN_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07582
GATA4-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16742
Kidney renal papillary cell carcinoma_KIRP_TCGA-AL-A5DJ-01A-11R-A26U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8139-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K99728124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11722
head	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K12202458	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3695
GSE145430_0_v_1_zmat3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KAT14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05587
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41786
CREB3L4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.502
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12486367-Supplementary_Data2.pdf-263-ZNF460_ZNF460	Rummagene Transcription Factor Associations 2026	1.0	null
RERF-LC-KJ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K44292107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29214
cotinine-2011	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
posterobasal nucleus, intermediate part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03477
Atrial fibrillation	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
BRD-K57045425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50546
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16097
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.41144
Perturb_106_KD_E2F4/E2F5_SRP296854	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.84622
SCC4	CCLE Cell Line Gene CNV Profiles	1.0	1.80168
BRD-K75649446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09974
H3K4me3_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Tucidinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0121898
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68443
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RET	Kinase Library Tyrosine Kinome Atlas	1.0	98.05
BRD-K85392247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54037
Metabolism of RNA	Reactome Pathways 2024	1.0	null
H3K27ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882889
RIPPLY1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.62732
ESR2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.3261
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BL3467 (SUPT6H)	NURSA Protein Complexes	1.0	null
GTEX-RU72-0011-R9A-SM-2TF67	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49414
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.889816
BRD-K76008396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36509
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
LA-42-ER00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.61802
TCF12	ENCODE Transcription Factor Targets	1.0	null
ME-31-RM40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.456102
GSE43041,GSE43044_0_v_1_ldb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.842412
H3K79me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE199606_1_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TKQ1-0926-SM-4DXU2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71109
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K43029808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24371
DCP1A-22483619-HELA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
BL2840 (UIMC1)	NURSA Protein Complexes	1.0	null
KMOE-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
dorsal spiriform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34563
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BL7546 (FOXP3)	NURSA Protein Complexes	1.0	null
Perturb_5609_OE|KO_Ikbkb|Stat3_SRP271148	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.2043
dorsolateral prefrontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.905158
inferior temporal gyrus, right, bank of mts	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.825327
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.07514
COLO775	CCLE Cell Line Gene Expression Profiles	1.0	2.43316
KP2	Achilles Cell Line Gene Essentiality Profiles	1.0	1.54097
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K32506050	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26371
demecarium bromide-1781	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
TAL1_G1E_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-4512-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K77011363	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92818
GSE211286_4_v_5_tcf12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SP-A6QC-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE153871_5_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K40103182	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.987
BRD-K58208155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37263
thioridazine-1986	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01536	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.33713
CW-2	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.06697
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1223
caco2	HPA Cell Line Gene Expression Profiles	1.0	0.990883
BRD-K31851055	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36268
BRD-K98355012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07127
Penis_Foreskin_Fibroblast_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.840592
H3K27ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
central nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.32373
GTEX-TML8-0001-SM-3NMAF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824897
QA-50-YO37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.906424
OVTOKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
KYO1	CCLE Cell Line Gene Expression Profiles	1.0	1.75896
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DG-A2KJ-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.59986
GTEX-WH7G-0002-SM-4LVN9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.84138
NMRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.09183
rectum_8d	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.901258
MORN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13613
COLO-320-HSR	GDSC Cell Line Gene Expression Profiles	1.0	1.92955
CREB	MotifMap Predicted Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AS-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN008_HEPG2_24H:O03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2386
Perturb_10319_KO_Pdk2_SRP216037	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
Chronic Disease	HuGE Navigator Gene-Phenotype Associations	1.0	null
respiratory system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.054328
PRPS2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19691
BRD-K84233365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09955
GSE230656_0_v_1_gsdmd_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KYSE-270	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.91059
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
17660535-TableS4a	GeneSigDB Published Gene Signatures	1.0	null
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLPB	Hub Proteins Protein-Protein Interactions	1.0	null
PMC12375500-41388_2025_3449_MOESM1_ESM.xlsx-DBP_down-gene_DBP	Rummagene Transcription Factor Associations 2026	1.0	null
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.68401
Perturb_8819_KD_TRRAP_SRP106050	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.87091
Mpp10 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.748
POLR2A_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
isthmic portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30683
BRD-K38929751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11808
Hippocampus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
BL1574 (CDC2L6)	NURSA Protein Complexes	1.0	null
PMC9859043-elife-78421-supp9.xlsx-LHX8_P-Gene_symbol_LHX8	Rummagene Transcription Factor Associations 2026	1.0	null
GSE173232_1_v_0_sf3b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-W5X1-2526-SM-3GILC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.855961
primary auditory cortex (core)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.29285
Skin Cutaneous Melanoma_SKCM_TCGA-QB-A6FS-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11165361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71817
hsa-miR-2392	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K93488589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49882
NFIC_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN011_HEPG2_24H:N09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0403
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EC-GI-10	GDSC Cell Line Gene Expression Profiles	1.0	2.2141
drofenine-6776	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
acute lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.253248
inner SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.911789
GSE166536_1_v_2_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K79me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3ac_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Cerebral Hemorrhage	HuGE Navigator Gene-Phenotype Associations	1.0	null
diclofenac-7215	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JAK1_druginhibition_165_GSE38335	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.28298
BRD-K68495784	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15867
GSE224599_0_v_1_tfcp2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE202434,GSE202438_3_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
mediodorsal nucleus of thalamus_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.23167
LOUCY	CCLE Cell Line Gene CNV Profiles	-1.0	-2.18244
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0011-R1A-SM-3TW8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.893028
OCIMY7	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38821
ESRRB	ChEA Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-M7-A71Z-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41715
Box H/ACA RNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.51
pwp2p-containing subcomplex of 90s preribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.48305
disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039148
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.47008
sarcomere	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.180339
SRF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cerebellar cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.59059
Liver Diseases	CTD Gene-Disease Associations	1.0	1.09047
intracellular membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
CGTH-W-1	GDSC Cell Line Gene Expression Profiles	1.0	1.67676
BRD-K16754572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68356
GTEX-S3XE-1526-SM-4AD5A	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91879
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CORL24	CCLE Cell Line Gene CNV Profiles	-1.0	-1.37675
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.60818
BRD-K25822126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38453
pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061104
posteroventral (inferior) parietal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19667
BRD-K31884664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01938
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
FE-56-PV35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.90454
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K79me2_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K89514545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25963
snorna binding	GO Molecular Function Annotations 2015	1.0	null
GTEX-T6MN-0011-R4A-SM-32QPG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916362
ENL-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
g-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger	GO Biological Process Annotations 2015	1.0	null
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35584
SNG-M	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE153867_6_v_4_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE121824,GSE121826_0_v_8_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KYSE30	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.50983
cellular nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
OF-98-RK57_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306769
HCC364	CCLE Cell Line Gene CNV Profiles	-1.0	-1.62852
CRCGN013_HEPG2_24H:P02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.04613
AA-86-YY62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.250284
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10133
Lung squamous cell carcinoma_LUSC_TCGA-46-6026-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE86507,GSE86509_7_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_1034_KO_Apoe_SRP197523	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.79663
Blood cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Brain Lower Grade Glioma_LGG_TCGA-DB-5274-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
AKT1_druginhibition_81_GSE26290	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.63732
diprophylline-1811	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RUNX3	ENCODE Transcription Factor Targets	1.0	null
shoot	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.112685
breast carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.312102
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L7-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Quinoprotein amine dehydrogenase, beta chain-like	InterPro Predicted Protein Domain Annotations	1.0	null
BRD-K81447429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11625
PMC5740759-40246_2017_131_MOESM1_ESM.xlsx-Table_S2-HSF1_CanSig_Genes-HSF1-CanSig_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.83268
NCI-H2196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31607
E2F4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-1626-SM-48TC9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.979428
CC-18-YW57_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.325538
MYC_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QMRM-0526-SM-2I5GA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.888939
OCI-LY-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0622
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
NCI-H1299	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00303
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IJ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
B-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.074
blood cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055156
TA-19-YA45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.311356
GTEX-NL4W-0011-R10A-SM-2I3DY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01342
NELFB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00519835
BL5506 (UACA)	NURSA Protein Complexes	1.0	null
GTEX-R55C-0326-SM-3GAF1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12663
AATF	Hub Proteins Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AQ-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KP3	CCLE Cell Line Gene CNV Profiles	1.0	1.51652
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
T98G	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.868197
NAP1L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.92877
contractile fiber part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.171149
AP3M1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.44075
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Uterus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51876
Kidney renal papillary cell carcinoma_KIRP_TCGA-Q2-A5QZ-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37506332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.76116
BL6311 (ELL)	NURSA Protein Complexes	1.0	null
KIF1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14417
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32283
preopto-hypothalamic band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02622
BL6346 (ATF2)	NURSA Protein Complexes	1.0	null
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.35584
endonucleolytic cleavage to generate mature 5'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	GO Biological Process Annotations 2025	1.0	null
GTEX-QV31-0126-SM-447BP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83624
NT5C3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00541079
SRF-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ANKRD52	Pathway Commons Protein-Protein Interactions	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.50275
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.09297
Lsm2-8 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.516
DC-93-NP78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.735382
FOSL2_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-62 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.906
HM13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.41122
GSE60691_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
inferior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06138
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DF-84-RT50_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.236003
BD-04-NG34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.629813
GTEX-S7PM-0011-R6A-SM-3NM8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26719
integument	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050339
PMC6977700-aging-12-102667-s006..xlsx-Sheet1-The_identified_941_dysregulated_LmiRM-CTs_in_MI_using_traditional_method_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.835163
CRCGN017_MCF10A.WT.HP_24H:L22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.34183
JARID1A-20064375-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
BRD-A14803952	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03036
GSE166315_1_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_14902_KO_Cdkn2a/Nf2/Bap1_SRP199809	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.63706
BL1021 (FAM184B)	NURSA Protein Complexes	1.0	null
BRD-K01237277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3115
RBL1	Pathway Commons Protein-Protein Interactions	1.0	null
AD-16-HL96_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.427119
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IL-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-0126-SM-4DM6O	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864497
GSE122711_2_v_3_mpc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.876447
PMC3419980-leu201249x6.xls-RUNX1-DHS-1000bp-Unnamed_0_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-22-5481-01A-31R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Primary hematopoietic stem cells G-CSF-mobilized Female RO_01508	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.15656
GTEX-R55D-0126-SM-48FEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.84912
Perturb_17264_KD_Pnldc1_ERP117333	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.26372
GC-42-LL86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203588
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824971
FAM3C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36596
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-z_e_o_To_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE220693_1_v_0_cgas_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CBC42 (NAT10)	NURSA Protein Complexes	1.0	null
lymphoblastoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094436
SW 837	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.873127
GSE229973_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.75307
TAL1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rpmi8226	HPA Cell Line Gene Expression Profiles	1.0	1.22495
VMRCRCW	CCLE Cell Line Gene CNV Profiles	1.0	1.53492
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VZ in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.972549
Fatty Liver	CTD Gene-Disease Associations	1.0	1.28703
TBL1XR1_02_43	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59223
internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Medulloblastoma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.907
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BL4546 (HMG20B)	NURSA Protein Complexes	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57503
mantle zone of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26181
BRD-K73531877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9615
H3K14ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ventral entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09336
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE206516,GSE206518_6_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-2626-SM-4DXV2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.881648
BECKER	CCLE Cell Line Gene CNV Profiles	1.0	1.37338
BL1739 (CARM1)	NURSA Protein Complexes	1.0	null
GM12878	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.44004
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K97452545	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59767
GSE60837_2_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ETS1-21867929-TH2-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
CRCGN017_MCF10A.WT.HP_24H:H08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.07858
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.41323
Perturb_17444_KO_Trp53_DRP003641	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-17.3382
GSE136622_0_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TBX19	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.4293
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7455079-jciinsight-5-140380-s227.xlsx-Supp_Table_8-ILL1_T_Cells_FOXP3_FOXP3	Rummagene Transcription Factor Associations 2026	1.0	null
Nucleus ambiguus, dorsal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16624
SG in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.65609
GSE244072_10_v_9_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.3769
Perturb_6314_KO_Atp4b_SRP238545	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
GTEX-XOT4-0626-SM-4B66L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910381
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7UY-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EPI-1970-1 (MAP1LC3A)	NURSA Protein Complexes	1.0	null
ZNF454	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21986
BL7075 (NFKBIB)	NURSA Protein Complexes	1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BL1003 (ATF7IP)	NURSA Protein Complexes	1.0	null
hepatitis	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.249608
ZNF667	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.7585
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-1081-01A-01R-0692-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CA-75-HA22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.419666
Perturb_3565_KD_BMI1_SRP297906	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.99568
Infralimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43239
PMC8017594-LSA-2019-00332_Table_S1_Table_12.xls-DCX-KD_LIS1-KD_DEGs-LIS1-KD_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K75967530	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46746
FEZF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.966
BL8104 (AHDC1)	NURSA Protein Complexes	1.0	null
BL2587 (NCOR2)	NURSA Protein Complexes	1.0	null
Urinary system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.04
PTBP1_02_144	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.6162
SNU-1040	COSMIC Cell Line Gene Mutation Profiles	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045065
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24978
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K72843176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13933
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HDAC6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11820137-elife-98152-supp9.xlsx-Summary-SERBP1_interactors_NOT_in_tau_aggregates_NR4A2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K45058172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15381
ETS1_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.36192
EZH2	ENCODE Transcription Factor Targets	1.0	null
clofilium tosylate-6830	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GABPA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL595 (APTX)	NURSA Protein Complexes	1.0	null
NOLC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.08441
CC-04-WK34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.319096
FA-36-VA24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.32839
BRD-K93503664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36974
BRD-K72602058	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38567
BA-69-TQ80_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217598
RBX1	Pathway Commons Protein-Protein Interactions	1.0	null
striatum_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.59722
GTEX-OIZI-0008-SM-2XCFD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.932932
GSE95685_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NR3C1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
episupraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02622
BRD-K81465091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1626
BRD-K18527484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.81468
intermediate stratum of THyB-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57802
GSE211177,GSE211178_8_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K24025166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24634
bone marrow	HPA Tissue Protein Expression Profiles	-1.0	-1.04297
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	GTEx Tissue Gene Expression Profiles	-1.0	-1.3337
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
SP2	ENCODE Transcription Factor Targets	1.0	null
CTCF-33576154-HUMAN-HILARLN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
BL4827 (CEP350)	NURSA Protein Complexes	1.0	null
H3K4me3_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1-23762244-HIPPOCAMPUS-RAT	ChEA Transcription Factor Targets 2022	1.0	null
SK-MG-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.98484
ETS1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K71537579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08136
EF-74-KW12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.33454
CBC752 (USP9X)	NURSA Protein Complexes	1.0	null
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-05A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K33606137	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64526
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13745
nucleus of the stria terminalis, medial division, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03306
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-U8T8-0126-SM-3DB94	GTEx Tissue Sample Gene Expression Profiles	1.0	0.953091
organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GSE173232_2_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-PX3G-0126-SM-2I3EN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15424
IE-80-DC24_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.404095
JUN_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2793-01A-01R-1201-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE239541_11_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
triangular septal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.49138
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GTEX-XBEC-1326-SM-4AT69	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44097
GSE242290_3_v_10_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K74198088	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79005
Uterine Carcinosarcoma_UCS_TCGA-N7-A4Y8-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_9608_KO_Sirt7_SRP223932	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.4374
GATA1_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0011-R1A-SM-2I5EW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29314
HS821T	CCLE Cell Line Gene CNV Profiles	1.0	1.38489
Bladder Urothelial Carcinoma_BLCA_TCGA-S5-A6DX-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K22475995	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0097
H3K4me3_G1E_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB33_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110440_2_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lateral hypothalamic area, tuberal region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21956
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.880525
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.49191
EGR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17356
BRD-K56761719	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.5737
cell part	LOCATE Curated Protein Localization Annotations	1.0	null
Perturb_3575_KO_Otx2_SRP279863	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.40021
BRD-K54790089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26409
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1568	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03828
cerebellum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27212
CTCF_MEL cell line_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-FC-A66V-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KDM5A	ChEA Transcription Factor Targets	1.0	null
VMRC-LCD	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13208
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OY-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lymphocytic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.074833
estradiol-1149	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COR-L321	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Necrosis	CTD Gene-Disease Associations	1.0	1.75738
fluphenazine-6954	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CREB1	ChEA Transcription Factor Targets	1.0	null
macromolecular complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.53653
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14705
Lung adenocarcinoma_LUAD_TCGA-MP-A4T6-01A-32R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE220520_5_v_9_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BL840 (UBE2A)	NURSA Protein Complexes	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.33407
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1-23762244-HIPPOCAMPUS-RAT	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
articaine-7272	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
tail of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.869539
JHOM2B	CCLE Cell Line Gene CNV Profiles	-1.0	-1.84119
GATA1	ENCODE Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-YY-A8LH-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-S4Q7-1026-SM-4AD75	GTEx Tissue Sample Gene Expression Profiles	1.0	0.914422
BL9429 (C7orf20)	NURSA Protein Complexes	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC4728380-ncomms10153-s8.xlsx-High_affinity_MYC_Targets-Unnamed_0_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VJYA-1426-SM-4KL1Y	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58918
BRD-K36027285	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47533
BRD-K72050226	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06586
inferolateral temporal cortex (area TEv, area 20)_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03225
ZNF274	ENCODE Transcription Factor Targets	1.0	null
BRD-K98682310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49215
BMS1	Hub Proteins Protein-Protein Interactions	1.0	null
TCF12_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SPI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99727034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39017
Lung adenocarcinoma_LUAD_TCGA-55-8506-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE184479_3_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K07536006	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11387
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR433	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07582
Perturb_12138_KD_OTX2_SRP347033	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.17926
USF2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PTRH1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00424857
Orbital area, medial part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05629
GTEX-XMD1-0011-R11A-SM-4AT5J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46347
PMC4332150-msb0011-0775-sd13.xlsx-JUN-Prey_Gene_Symbol_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
substantia nigra, pars reticulata, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.97404
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SMC1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
EA-39-YN88_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.9831
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.827903
BRD-K43388152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25316
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.983088
HD-29-LW24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.16263
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF528	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.888
KYSE-220	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-UF-A7JS-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_12698_KO_Ezh2_SRP222765	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.56892
subthalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.893431
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleomorph	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.344
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE184479_1_v_2_aim2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
nitrogen compound metabolic process	GO Biological Process Annotations 2015	1.0	null
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67531128	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.73201
CBC361 (MALT1)	NURSA Protein Complexes	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12271601-mmc2.xlsx-OUT_cells_03-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
GSE173578_1_v_0_atf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE239844_4_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SNOS-1126-SM-4DM67	GTEx Tissue Sample Gene Expression Profiles	1.0	2.74018
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96777
GTEX-P4QT-0126-SM-2I3FL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44146
SNTB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30584
salivarygland_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.16823
BL9430 (C7orf20)	NURSA Protein Complexes	1.0	null
KLE	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GATA1_G1E-ER4_mm9_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31502
Lung squamous cell carcinoma_LUSC_TCGA-34-8456-01A-21R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
animal	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K89806367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22964
BRD-K64698045	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.71871
SOX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10608
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
terminal subparaventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5785
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UTHO-0011-R1A-SM-3GIJO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.923941
MIA PACA-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895805
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
b-lymphocyte cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.712959
GTEX-U3ZN-0226-SM-3DB8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952923
8738_TBL3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.503513
H3K4me3_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_CH12.LX_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
orbital frontal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.878688
TAL1	ChEA Transcription Factor Targets	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ethinyl estradiol_oryzias latipes_gpl16266_gse44859	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COPI vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.093
GTEX-OXRO-0011-R9A-SM-3NB1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.96802
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.828861
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K08941280	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.32646
GSE220520_1_v_2_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CAL120_BREAST	CCLE Cell Line Proteomics	1.0	4.48208
BL131 (MSH6)	NURSA Protein Complexes	1.0	null
Perturb_17303_KO_Tam_SRP126482	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.71213
U2-type catalytic step 2 spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.743
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935568
Submedial nucleus of the thalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09874
Inflorescence primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.831
BL2667 (HDAC2)	NURSA Protein Complexes	1.0	null
hippocampus (hippocampal formation)_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.858464
BRD-K58643762	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00801
primary motor-sensory cortex (samples)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.19248
H3K4me2_H1 BMP4 Derived Mesendoderm Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
LOVO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K19225848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17243
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.22399
Bed nuclei of the stria terminalis, anterior division, anteromedial area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22485
16618758-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
SIX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8T8-1126-SM-4DXUE	GTEx Tissue Sample Gene Expression Profiles	1.0	2.13907
AURKB	Pathway Commons Protein-Protein Interactions	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE63048_11_v_8_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PDE10A_KO_GSE40377_581_mouse_Striatum and hippocampus	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
ARNT	Pathway Commons Protein-Protein Interactions	1.0	null
BRPF3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.56317
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01736
BRD-K60777422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33194
GTEX-S7PM-0626-SM-4AD4Q	GTEx Tissue Sample Gene Expression Profiles	1.0	2.25196
Carcinoma, Hepatocellular	CTD Gene-Disease Associations	1.0	1.30666
STAT5A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ascites	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K35668999	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07829
Perturb_13133_KO_Pnpt1_SRP134850	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.85053
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90114
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.71365
GSE247862,GSE247863_2_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K32049721	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36976
BRD-K59542165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12876
H3K4me1_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BL3564 (CDK5RAP3)	NURSA Protein Complexes	1.0	null
organic substance metabolic process	GO Biological Process Annotations 2015	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
septodiagonal transition area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11957
SNX11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00025
Perturb_4767_KO_Kap1_SRP065215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	12.264
BRD-K50413145	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58098
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_6855_KD_YTHDF1_SRP287222	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.36964
submammillothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28712
GSE164521_0_v_1_nitric oxide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Leaf base	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.567
Perturb_4812_KO_Stat5b_ERP004375	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.89261
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.38572
Exocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.1
BRD-K86467057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2052
HS172T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.80203
BRD-K85112460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10019
TOP1	Hub Proteins Protein-Protein Interactions	1.0	null
WD40/YVTN repeat-like-containing domain	InterPro Predicted Protein Domain Annotations	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838306
intracellular organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
Perturb_14243_KO_Tet1_SRP237910	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.29401
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PWO3-0926-SM-2I5EY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.930941
accessory entopeduncular nucleus (post-migratory)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03996
BL2986 (RBBP4)	NURSA Protein Complexes	1.0	null
EBF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A57536034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43367
SC-66857 (DCLK1)	NURSA Protein Complexes	1.0	null
organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.51822
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6HZ-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K41574232	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23148
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.082619
H3K27ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BD-96-HO33_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.45815
SRF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE110178_1_v_7_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
upper dorsal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28238
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RENT complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.574
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RKN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.896485
macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-QM-A5NM-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleolus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
BRD-K28036658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17897
H3K27ac_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09926
SMC3	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08626
outer SZ in superolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.66184
GTEX-PVOW-0726-SM-2XCF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01682
GTEX-QVUS-0011-R9A-SM-3GIJA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.996002
GTEX-T2IS-1526-SM-32QPR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05052
PA-75-VL17_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.683032
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
paracentral lobule, posterior part, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06067
H3K4me1_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-A48D-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945477
CTCF_MEL cell line_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300	ENCODE Transcription Factor Targets	1.0	null
GSE244072_10_v_3_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BL1805 (MTA1)	NURSA Protein Complexes	1.0	null
FOXA1-26457646-LHSAR-HUMAN-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
POLR2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFJO-0002-SM-3P61X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35667
BL2837 (UIMC1)	NURSA Protein Complexes	1.0	null
H3K4me1_CH12.LX_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
intracellular organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
H3K4me1_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_315_OE_Cd4_SRP375640	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
CRCGN013_HEPG2_24H:I14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.78735
lower dorsal perifornical nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19176
BRD-K29936219	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18708
GSE248769_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE191105_2_v_4_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC1937_BREAST	CCLE Cell Line Proteomics	1.0	4.46225
Genetic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.049
GATA4-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
496100385_TCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.32486
intermediate stratum of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11819
Perturb_4367_KO_Peg10_SRP167954	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.0834
Bladder Urothelial Carcinoma_BLCA_TCGA-E7-A519-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K81782447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44339
BL3622 (DTX3L)	NURSA Protein Complexes	1.0	null
Creb5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.4558
intracellular part	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K40923781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09958
DV90_LUNG	CCLE Cell Line Proteomics	1.0	2.80488
Perturb_10332_KO_Pkd2/Mir21_SRP059062	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.06084
ESR1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.781
GSE179031_3_v_1_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FF-86-NH56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.241042
superficial stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50074
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.28192
HUH6	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87824
organelle part	GO Cellular Component Annotations 2015	1.0	null
WC-16-IR43_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.244331
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PUR1	MotifMap Predicted Transcription Factor Targets	1.0	null
Sarcoma_SARC_TCGA-MJ-A850-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K90686617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58507
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK4_all_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05448
PGR-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_1124_KO_Myc_SRP168941	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.62895
AF-72-PP21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.338033
RARB-24833708-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BL580 (MDC1)	NURSA Protein Complexes	1.0	null
female reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
ELF1	ENCODE Transcription Factor Targets	1.0	null
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.955614
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27042
SMARCB1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUPT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45432
Uterine cervix	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K02060635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52446
SNU-638	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.877
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A7-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HB-06-WU12_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.50639
BRD-K93884191	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19128
RPL13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04487
CTCF_cortical plate_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Huntington's Disease_CNS - Brain - Striatum (MMHCC)_GSE7958	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.9351
GTEX-WHSE-0126-SM-3NMBT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.45088
Edinger-Westphal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.17692
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13346
CRCGN017_MCF10A.WT.HP_24H:O17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.2027
NCIH810	CCLE Cell Line Gene CNV Profiles	1.0	2.88415
PANC0213	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51293
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EM-01A-21R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dense fibrillar component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.927952
GSE136622_6_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Ribonucleoprotein complex	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
MER	Kinase Library Tyrosine Kinome Atlas	1.0	97.0
ERG_01_216	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.64459
mfe296	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.722
GTEX-PX3G-0008-SM-48U2L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14378
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4515	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
principal sensory nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.41592
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LM-1685-612	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G-protein beta WD-40 repeat	InterPro Predicted Protein Domain Annotations	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-KQ-A41N-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC630	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.22436
Perturb_6830_KO_MTA1_SRP173632	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.46214
cellular metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K38966099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17802
BRD-K04546974	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13127
GSE137818_2_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
alar part of terminal hypothalamus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34444
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
USF1_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ECC10	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NFYA	ENCODE Transcription Factor Targets	1.0	null
nisoxetine-3117	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
LBP-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Perturb_11340_KD_Mll4_SRP241682	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.91119
GSE199660_1_v_0_secretin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BL2285 (ZC3H13)	NURSA Protein Complexes	1.0	null
GTEX-QESD-1426-SM-2S1R9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26726
BRD-K92650579	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.67355
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Subarachnoid Hemorrhage	HuGE Navigator Gene-Phenotype Associations	1.0	null
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK4_unique_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041678
GSE103372_0_v_3_smad1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BL2429 (NCOA4)	NURSA Protein Complexes	1.0	null
GTEX-PW2O-1426-SM-48TCD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.147
PMC12120020-41467_2025_60228_MOESM3_ESM.xlsx-387-456_GSC_vs_DGC-Accession_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
a band	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.540706
Cytosolic small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.071
Temporal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
FOSB::JUN	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.5448
GSE131649_6_v_7_hemin_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleolus	GO Cellular Component Annotations 2023	1.0	null
GSE229671,GSE229673_0_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A6I3-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB11	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.1244
PMC11884789-elife-103259-supp3.xlsx-Sheet1-Supplementary_file_3_Comparison_of_proteins_that_interact_with_R-loops_in_different_studies_to_RBPs_identified_in_NRL_interactome_NRL	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_10261_KO_Esrrg_SRP119935	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.89585
hematopoietic system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.060339
ETS2	MotifMap Predicted Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-39-5035-01A-01R-1443-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K44582497	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.626
Liver hepatocellular carcinoma_LIHC_TCGA-G3-A25S-01A-11R-A16W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LIN28B	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WZTO-0126-SM-3NM95	GTEx Tissue Sample Gene Expression Profiles	1.0	0.983256
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
salivary gland	HPA Tissue Gene Expression Profiles	1.0	1.4495
BRD-K73692505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06972
BD-61-OO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.470449
H3K4me1_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7325-01B-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2208
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
HELA	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.33254
BRD-K91843292	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22
ETS1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-0126-SM-4AT4H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882537
BRD-K08982277	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4481
first (dorsal) preoptic domain	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08122
GTEX-TSE9-1226-SM-4DXTM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.844655
reticular nucleus of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.3423
Chromatin silencing complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.704
4578_LIG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.696848
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
facial motor nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18189
HD-62-KE69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.27938
BRD-K05221385	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.04466
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37541
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-A6DA-01A-31R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBC183 (BICD2)	NURSA Protein Complexes	1.0	null
AA-52-JS03_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204483
inferolateral temporal cortex (area TEv, area 20)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.62984
SIX5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.91692
Trolox C-1734	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
PMC4653014-oncotarget-06-20404-s004.xls-only_detected_in_AFAP1-AS1_KD-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
17676974-TableS2	GeneSigDB Published Gene Signatures	1.0	null
skin	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.053842
A427	GDSC Cell Line Gene Expression Profiles	-1.0	-1.83424
H3K4me3_Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE113106_2_v_5_dnm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05353
BL1826 (TAOK3)	NURSA Protein Complexes	1.0	null
BL8107 (AHDC1)	NURSA Protein Complexes	1.0	null
RAD21_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KASUMI1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73226
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
NSD1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16916
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240896,GSE240899_2_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor cortex (area M1, area 4)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05614
Lung adenocarcinoma_LUAD_TCGA-49-4490-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JARID1A-20064375-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
U3 snoRNA binding	GO Molecular Function Annotations 2025	1.0	null
cell	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me1_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850483
intermediate stratum of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44211
BRD-K02630367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69495
intracellular membraneless organelle	GO Cellular Component Annotations 2025	1.0	null
lateral ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.00602
Pancreas	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.11945
GSE80446_2_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
colon_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.03129
GSE229671,GSE229673_2_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
heterocyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
GABPA_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
APLP2_KO_GDS4414_536_mouse_adult cortex	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.41681
intracellular membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K24333636	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29969
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MKN-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.24965
Perturb_14565_KO_Got2_SRP348541	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.43242
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06486
ventrolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01323
BL1756 (MED23)	NURSA Protein Complexes	1.0	null
COLO 800	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67488
SYNRG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23439
placenta	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-0.847961
BRD-K87412446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2949
r10 part of the vestibular column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28428
SW982	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BL2600 (BRIP1)	NURSA Protein Complexes	1.0	null
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61457
BRD-K27008344	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60988
GSE246053_1_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-UPIC-1526-SM-4IHLU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.948609
Cytosolic large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.757
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
Epimastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.642
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
imatinib_homo sapiens_gpl96_gds3043	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE172295_0_v_2_sh3gl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K23461342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55535
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
FB-39-CW59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.92127
ZBTB7B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.2264
MES-SA	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYLK_knockdown_48_GSE14525	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.21881
vertical nucleus of the diagonal band	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26767
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6418
Perturb_6786_Mut_KRAS_ERP122260	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.7166
Retinal stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.672
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CE-95-YX02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.300868
GTEX-V955-0726-SM-3GAFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31108
TAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stratum oriens of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.86297
SG in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.879007
APLP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.6788
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9270251-mmc2.xlsx-2_Filtered_DEGs_Control_vs_KD_2-Gene_ID_AR	Rummagene Transcription Factor Associations 2026	1.0	null
HNF1A-27111144-CD8+TCELLS-MOUSE-BLOOD-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
WC-59-RG09_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.206099
cell part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.050004
TMEM161A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37317
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26576
Box H/ACA snoRNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.704
posterior (caudal) superior temporal cortex (area 22c)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.837005
head of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.965401
488395315_TCx_no dementia_no TBI_90-94_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.52255
SC-28749 (NCOA4)	NURSA Protein Complexes	1.0	null
Vascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.273
GTEX-OOBK-0526-SM-2HMJJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904085
H3K4me1_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
EP300_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.28644
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rrna metabolic process	GO Biological Process Annotations 2015	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67K-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BA-19-VU85_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.661117
Lung squamous cell carcinoma_LUSC_TCGA-43-5668-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.65677
head	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050811
Nuclear DNA-directed RNA polymerase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.422
trifluridine-5819	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
QA-34-PH05_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229295
ChIP_ASH2L_23239880	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47775
Heart	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.09188
FOXM1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL129 (MSH6)	NURSA Protein Complexes	1.0	null
PMC12721900-jci-136-187998-s161.xlsx-Flag-ETS1_vs_vector-Gene_ETS1	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of PO1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08301
Breast Cancer_Mammary Gland Tissue_GSE1872	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.49595
Cerebrovascular disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.273
Perturb_1006_KO_Bcl9l/Bcl9_SRP045828	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.31102
rostral group of intralaminar nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.878656
PFKL_OE_GDS1980_203_mouse_dermal fibroblasts	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
g-protein coupled receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
SPI1_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13108_KO_Mbnl1/Mbnl2_SRP045573	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.56771
GSE137914_0_v_5_tet3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K10943878	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.14974
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
substantia nigra reticulata, m1 part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4092
periventricular stratum of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65225
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Fibrosis	CTD Gene-Disease Associations	1.0	1.19345
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NE-94-VE83_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.328817
CTCF_MEL cell line_mm9_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PP-1626-SM-2HMJF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.50326
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10389
Acute Myeloid Leukemia_LAML_TCGA-AB-2952-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19457
BB-86-BE19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.06067
Ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.773
TCF3	ENCODE Transcription Factor Targets	1.0	null
TC-02-NZ28_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.500403
liver disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.076771
CEBPD	ENCODE Transcription Factor Targets	1.0	null
BE-92-TW08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22141
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K07281036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21313
PMC11502753-41467_2024_53330_MOESM11_ESM.xlsx-Sheet1-SMAD3_target_genes_hES_SMAD3	Rummagene Transcription Factor Associations 2026	1.0	null
GSE193993_1_v_2_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
hepatocellular carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.166319
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81443
8738_TBL3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.589991
GSE149264,GSE149267_4_v_5_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233112_2_v_3_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-SNU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K9ac_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_10244_KO_Klf6_SRP261836	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.56619
intracellular organelle	GO Cellular Component Annotations 2015	1.0	null
GTEX-XMK1-2026-SM-4B65K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53217
lateral part of MM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.75388
oral mucosa	HPA Tissue Protein Expression Profiles	1.0	1.04464
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
imatinib_homo sapiens_gpl96_gds3047	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K08806664	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67195
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.0625
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13002
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.51812
RPL15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39062
NCIH810	CCLE Cell Line Gene Expression Profiles	1.0	1.68802
lymphoblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.090305
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-54-GQ68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.74281
Perturb_16812_OE_HNF1A/FOXA3/PROX1_SRP167105	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.02129
SRF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lm11	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.855
GTEx Prostate 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-4.59288
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16279
Ascites	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.3
GSE155305_2_v_0_ifitm3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
snoRNA binding	GO Molecular Function Annotations 2025	1.0	null
Perturb_1275_KO_Ptpn2_SRP108032	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.17095
GTEX-WVLH-0011-R4A-SM-3MJFS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.872638
Acute Myeloid Leukemia_LAML_TCGA-AB-2920-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
leukocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.06944
BRD-K13016489	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75579
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.72089
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63074
inferolateral temporal cortex (area TEv, area 20)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.0396
BL5558 (TOM1)	NURSA Protein Complexes	1.0	null
interstitial nucleus of Cajal, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.463
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203060_0_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Epithelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
GABPA_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
m1AD (DM) part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06514
HGC-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49566
Perturb_6291_KO_ZNF165_SRP390251	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.95761
GSE173810_0_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K17063694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04088
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
GSE243491_1_v_0_oxaliplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-P3-A6SX-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TT2609C02	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53223
TAL1	ENCODE Transcription Factor Targets	1.0	null
GSE198165,GSE198166_7_v_11_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.71759
SC-28236 (BAP1)	NURSA Protein Complexes	1.0	null
DENND1C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.884
8820_TERF2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.511956
GSE124410_3_v_0_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
adrenal gland	HPA Tissue Protein Expression Profiles	1.0	1.04464
GSE229973_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE138019_3_v_2_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K59517185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61652
BL4209 (TCEB3)	NURSA Protein Complexes	1.0	null
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56431
AF4-26711339-SEM-HUMAN-BLOOD-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2979-03B-01T-0760-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
90S preribosome	GO Cellular Component Annotations 2023	1.0	null
BRD-K63401627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17757
nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
lymphoid cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.069571
BRD-K37271110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.44318
BRD-K06974027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92297
GSE110178_5_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K59667434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10142
GSE190384,GSE190386_0_v_8_fulvestrant_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Ebolavirus(EBOV)_1day_PBMCs_17725815_GSE8317	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.858738
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.06644
SIN3A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10132
CRCGN016_MCF10A.WT.HP_24H:O09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.34788
GSE226983_2_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K52876244	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37326
BRD-K40206099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30655
BRD-K89805365	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03617
Palpus	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.599
CRCGN008_HEPG2_24H:O05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.25592
EBF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K12015168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0398
Perturb_3716_KD_PIWIL1_SRP188921	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.44067
BRD-K14216332	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.64813
GSE142684_0_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BL2126 (HDAC3)	NURSA Protein Complexes	1.0	null
Perturb_17504_KO_Lats1/Lats2_SRP239191	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.45605
GSE140607_0_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U4B1-1526-SM-4DXSL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75217
Brain Lower Grade Glioma_LGG_TCGA-FG-A60L-01A-12R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0518
YY1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKRN2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14307
GSE205913_1_v_0_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SC-12739 (CSNK2B)	NURSA Protein Complexes	1.0	null
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SKNO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.87753
H3K27ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
GTEX-QMR6-0011-R1A-SM-32PKW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16651
oxytetracycline-1553	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE219274,GSE219276_0_v_1_doxorubicin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RFX5	ENCODE Transcription Factor Targets	1.0	null
tretinoin_homo sapiens_gpl6244_gds4180	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37356
PMC5054126-mmc4.xls-SCX_GPM-Protein_identification_by_GPM_databse_search_from_SCX_fractionated_samples_SCX	Rummagene Transcription Factor Associations 2026	1.0	null
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51797
BRD-K96981233	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1961
AE-13-CX28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.213399
Perturb_5308_KO_Tet1/Tet2/Tet3_SRP101434	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.87168
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DD-75-HY40_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.836086
lorglumide-6456	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K39571490	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09605
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TEAD4	ENCODE Transcription Factor Targets	1.0	null
MAP2K2	MSigDB Cancer Gene Co-expression Modules	1.0	null
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RWSA-0008-SM-47JYX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900001
HDAC2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.901267
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.924087
ACHN	CCLE Cell Line Gene CNV Profiles	1.0	1.7727
GABPA	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WY7C-2326-SM-3NB2U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.905971
BRD-K56417082	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37091
BL285 (RFC5)	NURSA Protein Complexes	1.0	null
SC-7216 ()	NURSA Protein Complexes	1.0	null
APPBP2	Pathway Commons Protein-Protein Interactions	1.0	null
PMC6070530-41398_2018_200_MOESM3_ESM.xlsx-regional_cluster_PFC-MSC-age-bin_8_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
BL1576 (ESCO1)	NURSA Protein Complexes	1.0	null
NCI-H524	GDSC Cell Line Gene Expression Profiles	1.0	1.83157
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_10899_KD_Mdr2_SRP055450	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.87436
BD-49-MD69_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.10236
STAT6	MotifMap Predicted Transcription Factor Targets	1.0	null
CRCGN015_MCF10A_48H:H03	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	4.02447
mantle zone of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.57669
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
tonsil_8b1	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.00913
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16689648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71059
BRD-K98535708	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10871
AB-33-EM56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.716888
BRD-K78323315	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43572
JAK2	Kinase Library Tyrosine Kinome Atlas	1.0	96.67
BB-62-SZ35_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.465322
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BL4957 (ZNHIT3)	NURSA Protein Complexes	1.0	null
OB glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.99291
BL1004 (ATF7IP)	NURSA Protein Complexes	1.0	null
NELFA-20434984-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
COR-L47	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.01398
inferolateral temporal cortex (area TEv, area 20)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.926418
BRD-K30145193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03413
RKO	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.39221
Perturb_16721_KO_Brca1_SRP094855	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.73975
CHD4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K18737347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28672
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05652
HS 766T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37695
BL8109 (RAD54L2)	NURSA Protein Complexes	1.0	null
AB-64-ZX70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260037
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.828399
ELF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular part	LOCATE Curated Protein Localization Annotations	1.0	null
GSE239541_5_v_7_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_11 yrs_F_12289	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.127
NCI-H2804	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869499
P53-21459846-SAOS-2-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
r11 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23092
H3K79me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
benfluorex-2621	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.3455
GTEX-T5JW-1626-SM-3GADZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35133
anterior orbital gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41851
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN014_HEPG2_3H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.8561
BRD-K33260002	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94858
LS-180	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HCA-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28478
Lung adenocarcinoma_LUAD_TCGA-86-8668-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_5448_OE_Vegfa_ERP109687	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.60225
nuclear part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
NCAPG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00424977
NUDCD1	Pathway Commons Protein-Protein Interactions	1.0	null
uterus	GTEx Tissue Gene Expression Profiles	1.0	1.05722
MYC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828445
GSE153871_4_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GM2313	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.01378
GTEX-RVPU-0011-R1A-SM-2XCAI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.03996
CLPSL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18015
U5 snRNP	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.822
CTCFL	ENCODE Transcription Factor Targets	1.0	null
metabolic process	GO Biological Process Annotations 2015	1.0	null
nucleic acid metabolic process	GO Biological Process Annotations 2015	1.0	null
thoracic cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.051877
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.812
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.870285
epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055164
BL117 (ATR)	NURSA Protein Complexes	1.0	null
premotor cortex (area 6)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.840363
PMC7265345-41598_2020_65638_MOESM5_ESM.xlsx-2_E2F1-Gene_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-7351-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fenspiride-1422	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE181003_1_v_2_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE182680,GSE182683_5_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.850483
NCI-H810	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.73897
BRD-K57226763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54429
suxibuzone-2503	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
AC-05-MR83_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.506836
intermediate stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31632
Brain Lower Grade Glioma_LGG_TCGA-R8-A73M-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3948_KD_ETV5_SRP137003	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.28477
Perturb_15546_KO|KD_Tip5|Pten_SRP199649	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.34159
NCIH1048	CCLE Cell Line Gene Expression Profiles	-1.0	-1.92025
Perturb_1031_KO_Apoe_SRP197523	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.81573
BRD-K71590663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51518
CRCGN008_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05925
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHWD-1826-SM-3LK6I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09142
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.244094
Lung adenocarcinoma_LUAD_TCGA-78-8640-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary auditory cortex (core)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.918584
rRNA processing	Reactome Pathways 2024	1.0	null
SKNMC_BONE	CCLE Cell Line Proteomics	1.0	2.84355
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02288
ZNF263	ENCODE Transcription Factor Targets	1.0	null
8229_SNRPD2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.642011
Head and Neck squamous cell carcinoma_HNSC_TCGA-TN-A7HL-01A-11R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
FOSL2	ENCODE Transcription Factor Targets	1.0	null
mediodorsal nucleus of thalamus_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.04155
Perturb_12765_KO_Atg7_SRP273122	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.38354
pirenzepine-1388	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.378
Perturb_4518_Mut_Tip60/Ep400_SRP081300	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.89001
KBTBD7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34663
RUNX1-20887958-HPC-7-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
STOCK1N-35215-6422	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE114258_3_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PPP6R3	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K90877053	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36617
Bladder Urothelial Carcinoma_BLCA_TCGA-FJ-A871-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE154936_3_v_4_remdesivir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cSARS Bat SRBD_72Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.44545
Perturb_5857_KD_Apc_SRP076100	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.93321
Perturb_4805_KO_Mapk1_ERP004375	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.49164
BL8654 (BCCIP)	NURSA Protein Complexes	1.0	null
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_3903_KD_HNF4A_SRP123224	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.04027
H3K4me1_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
seminal vesicle	HPA Tissue Protein Expression Profiles	-1.0	-1.04297
GSE93309_5_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BL8111 (RAD54L2)	NURSA Protein Complexes	1.0	null
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-361	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
mcf7	HPA Cell Line Gene Expression Profiles	1.0	1.6542
H3K27ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
RA-27-ST16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.457118
CBC801 ()	NURSA Protein Complexes	1.0	null
H3K4me2_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Penis_Foreskin_Melanocyte_Primary_Cells_skin01	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.4785
CBC171 (AGAP3)	NURSA Protein Complexes	1.0	null
BRD-K52428486	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16488
Nucleoli	CM4AI U2OS Cell Map Protein Localization Assemblies	1.0	null
HCC2279	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.935754
Perturb_4780_KD_Trp53_ERP016337	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.19737
Cardiovascular system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
repaglinide-5862	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
DD-42-PC65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.681651
RELA_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Familial combined hyperlipidaemia_lymphoblast_GSE1010	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.52913
BA-84-WN26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.28041
H1 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-0.857684
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.07
BRD-A90249268	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54432
intracellular	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me1_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
MYC_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K62170825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11308
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10798
outer SZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.49283
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
lm12	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.978
Cellular anatomical entity	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.603
ZNF384	ENCODE Transcription Factor Targets	1.0	null
GTEX-XV7Q-2926-SM-4BRUL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32779
HCT-15	COSMIC Cell Line Gene Mutation Profiles	1.0	null
exocrine pancreas	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.30032
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP53	ChEA Transcription Factor Targets	1.0	null
BL3106 (APC)	NURSA Protein Complexes	1.0	null
DHX30	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XMD1-0011-R3B-SM-4AT5R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22775
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.91572
DU-4475	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.95241
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.844695
NCI-H2141	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.39966
GSE114232_8_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KDM5A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ES-Bruce4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FBL	MSigDB Cancer Gene Co-expression Modules	1.0	null
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.603
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26063034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4336
BL2881 (CHEK2)	NURSA Protein Complexes	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-OE-A75W-01A-12R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Inflammation	CTD Gene-Disease Associations	1.0	1.35328
BRD-K93519076	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61858
6555_POLR3A_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.691431
ZEB1	ENCODE Transcription Factor Targets	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96614
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AO-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-VM-A8CF-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KMRC1_KIDNEY	CCLE Cell Line Proteomics	1.0	4.01174
AB-33-EM56_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.356831
GSE109913_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
bl20	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.953
mRNA_NIPBL_20720539	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BL970 (TRPM2)	NURSA Protein Complexes	1.0	null
BRD-K90526956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4862
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DHX36	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14655
AA-58-FJ71_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.223803
BRD-K37696710	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.87491
GSE144796_3_v_0_linagliptin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
indusium griseum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.67792
BRD-K56881825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88331
GSE153757,GSE153758_0_v_3_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.915628
90S preribosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Perturb_11740_KO_Trp53_SRP221563	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.62831
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.935006
Perturb_17585_KO_Nubpl_ERP016523	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.80112
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01548
imatinib_homo sapiens_gpl96_gds3045	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCCPAN2	CCLE Cell Line Gene CNV Profiles	1.0	1.40965
GTEX-XMD1-0011-R10A-SM-4AT4A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.988724
POLR2A_bone marrow_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCOR1-26117541-K562-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K22584556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38536
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A50837272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11781
Perturb_13134_KO_Pnpt1_SRP134850	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.14455
ASH2L	ChEA Transcription Factor Targets	1.0	null
BL9239 (GREB1)	NURSA Protein Complexes	1.0	null
u87	HPA Cell Line Gene Expression Profiles	-1.0	-1.26401
FOXP2	ENCODE Transcription Factor Targets	1.0	null
Bone marrow cancer cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Female cone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.748
BRD-K61366105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51344
MDA MB435	BioGPS Cell Line Gene Expression Profiles	1.0	0.911676
BL5973 (ZC3H11A)	NURSA Protein Complexes	1.0	null
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.70071
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K75514760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05242
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GD-66-XE49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.286734
GSE184884_2_v_1_gps2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
stomach	HPA Tissue Protein Expression Profiles	1.0	1.04464
BD-50-HU68_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.277731
HCT116	BioGPS Cell Line Gene Expression Profiles	1.0	1.89587
GSE113106_0_v_4_dnm2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
primary motor-sensory cortex (samples)_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.21545
COV318	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07863
CIITA-25753668-RAJI-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
NCI-H1838	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895805
Nucleus ambiguus, ventral division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43621
Medial habenula	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.84703
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE116299_4_v_3_folic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Sarcoma_SARC_TCGA-DX-A8BK-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VDR	ChEA Transcription Factor Targets	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07823
r11 part of spinal trigeminal nucleus, caudal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.41355
caudal ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.85238
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BL5529 (CCDC99)	NURSA Protein Complexes	1.0	null
H3K4me3_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946831
BL1022 (FAM184B)	NURSA Protein Complexes	1.0	null
BRD-K39153737	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10084
ASH2L-23239880-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
HF-91-IU60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.313446
HCC-202	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	0.904329
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GRANTA-519	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.26015
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13212_KO_Lima1_ERP128082	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.09411
YY1	ENCODE Transcription Factor Targets	1.0	null
ZSCAN29	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.0054
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GC-08-VP20_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.213768
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial layers of caudal presubiculum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.10483
ERF::SREBF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.9445
BRD-K57784254	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.54711
SOX5	JASPAR Predicted Transcription Factor Targets	1.0	null
HS751T	CCLE Cell Line Gene Expression Profiles	-1.0	-1.58538
16728981-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
BL2507 (TLK1)	NURSA Protein Complexes	1.0	null
ATF3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE108495_1_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC5358377-pnas.1615015114.sd02.xlsx-Sheet1-genes_with_VDR_peaks_with_and_without_D3_VDR	Rummagene Transcription Factor Associations 2026	1.0	null
riluzole-2334	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K39962926	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0232
COLO818	CCLE Cell Line Gene Expression Profiles	-1.0	-1.64471
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
outer SZ in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.838408
superficial stratum of r2BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29938
dorsolateral prefrontal cortex_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.52263
BRD-K80724972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25425
SUMO1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K43352598	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39696
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.905335
DF-00-DK69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.223872
Perturb_10125_KD_ACP1/APC2_SRP061848	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-9.89303
GABPA_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.056138
GTEX-OHPN-0011-R7A-SM-2I5FI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890526
Perturb_4976_KO_Kmt2d_SRP107208	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.74736
GSE180185_7_v_1_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ND-39-PO34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.363647
GTEX-TKQ2-1526-SM-4DXUN	GTEx Tissue Sample Gene Expression Profiles	1.0	3.05803
SIN3A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL2381 (TAOK1)	NURSA Protein Complexes	1.0	null
GTEX-Q2AI-0526-SM-2I3EJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907659
DHX33	Pathway Commons Protein-Protein Interactions	1.0	null
superficial stratum of r1BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.5774
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
non-membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
GSE71385_1_v_0_cdk8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AK5ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_16308_KO_BUD31_SRP335732	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GCIY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TMEM160	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16316
BL1966 (RANBP1)	NURSA Protein Complexes	1.0	null
GSE136622_7_v_3_srpk3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part, lateral zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00265
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K36me3_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL1798 (BCL11B)	NURSA Protein Complexes	1.0	null
CTCF	ENCODE Transcription Factor Targets	1.0	null
BRD-K89701103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02499
Perturb_5608_OE_Ikbkb_SRP271148	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	18.8539
urogenital system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-21-5782-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SF539	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.01936
Prostate adenocarcinoma_PRAD_TCGA-KK-A6E3-01A-21R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC8355885-gutjnl-2020-320652supp004.xlsx-RALY_KD_mRNA-seq-Table_3_RALY_Knockdown_in_HCT116_cells_mRNA-seq_log2_FC_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5054126-mmc4.xls-SCX_Mascot-Protein_identification_by_Mascot_databse_search_from_SCX_fractionated_samples_SCX	Rummagene Transcription Factor Associations 2026	1.0	null
thioridazine-6189	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NALM6	Achilles Cell Line Gene Essentiality Profiles	1.0	1.03103
Perturb_9383_KD_Cdk19_SRP197255	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
whole body	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
mecamylamine-hcl	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26174
CYP27B1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36769
ZNF384_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
jaw	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.384766
BL2383 (TAOK1)	NURSA Protein Complexes	1.0	null
PMC6604319-13072_2019_278_MOESM3_ESM.xlsx-GSEA_TET1-CCRF-CEM_SCR_vs_TET1_TET1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-OOBJ-2126-SM-3NB1N	GTEx Tissue Sample Gene Expression Profiles	1.0	2.26894
SA1-22415368-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K12607407	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38559
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10094
ZFP42	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.3396
GSE113734_1_v_2_qprt_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SCYL1_knockdown_194_GSE57646	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.93487
eNoSc complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.686
BL5930 (SPAG5)	NURSA Protein Complexes	1.0	null
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
dorsal part of JcP	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44297
nucleus	GO Cellular Component Annotations 2015	1.0	null
BL1034 (ADNP)	NURSA Protein Complexes	1.0	null
CD105+_Endothelial	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.959072
BRD-K12411112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42566
H3K27ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
dexamethasone_homo sapiens_gpl4133_gse42619	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Preribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.856
cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-T2-A6WZ-01A-21R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PDK1_knockout_80_GSE26290	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.60333
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.066
CP in caudal subicular cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.39628
BRD-K91354770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47182
MAX_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8141_KD_MAGOH_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.08548
MAX	ENCODE Transcription Factor Targets	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.89857
male reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16351
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.41574
GMIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.88218
PMC5524348-pone.0181667.s005.xlsx-Inflammation-MINT_SPEN	Rummagene Transcription Factor Associations 2026	1.0	null
organic cyclic compound binding	GO Molecular Function Annotations 2015	1.0	null
Perturb_1781_KO_Hmces_SRP262047	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.94793
PMC10836071-media-2.xlsx-Supplementary_Table_5-ELK4_all_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K27858225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.84788
LGE-VZ border region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.45771
GSE206516,GSE206518_1_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10223
Perturb_6784_KD_ARID1A_ERP114370	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.57925
Interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03498
Hep-G2 cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	1.16933
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A69H-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE216352,GSE216354_1_v_0_keap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SRF_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE223540_1_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hematopoietic cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.062811
CRCGN017_MCF10A.WT.HP_24H:E14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.71247
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JU-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PARP1	Hub Proteins Protein-Protein Interactions	1.0	null
BL3693 (DLGAP5)	NURSA Protein Complexes	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7304-02A-12R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.27981
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.09339
GSE205540_2_v_3_phloridzin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-O5YT-2126-SM-3MJGD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21194
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4334-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
PMC5497057-ncomms15921-s2.xlsx-AA_PCa_vs_AA_NP-Unnamed_2_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL1789 (PAXIP1)	NURSA Protein Complexes	1.0	null
BC-01-JL64_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.222295
H3K4me3_CH12.LX_mm9_5	ENCODE Histone Modification Site Profiles	1.0	null
LM6 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.754
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.923811
PMC2530868-gb-2008-9-7-r111-S5.xls-Dec_hgu133_AAG-AA-Unnamed_1_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE156708_1_v_0_fbxo11_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SINHCAF	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07028
BL2418 (UBAP2L)	NURSA Protein Complexes	1.0	null
GSE153871_0_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HS 940.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.856039
rt4	HPA Cell Line Gene Expression Profiles	-1.0	-1.40719
TERALPHA	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE142430_3_v_0_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
G22	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.984048
GTEX-SNMC-0126-SM-2XCFO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2339
AE-09-SG21_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.310668
HuCCT1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.64032
BL3695 (DLGAP5)	NURSA Protein Complexes	1.0	null
GTEX-P4PP-0126-SM-3LK69	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42277
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S4Q7-1226-SM-4AD5I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.97086
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-LP-A4AV-01A-11R-A32Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1728_KO_Mdmx/Spi1_SRP301763	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.96362
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44548
Uterine Carcinosarcoma_UCS_TCGA-NG-A4VU-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XYKS-1726-SM-4E3IO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927135
GTEX-S4UY-0126-SM-3K2BB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03797
FB-49-NW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.225028
GTEX-NL3H-0011-R2a-SM-2I3GG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57109
hepatobiliary disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053571
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral hypothalamic area, anterior region, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07216
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72719
BRD-K93663012	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09634
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MXI1	ENCODE Transcription Factor Targets	1.0	null
Perturb_4783_KD_Trp53_ERP019861	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.19737
PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34182
Perturb_4257_KD_AR_SRP184695	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.75398
GTEX-XBEC-0126-SM-4GIDT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73436
BL373 (TOPBP1)	NURSA Protein Complexes	1.0	null
BRD-K20024170	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34514
MIAPACA2	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.06435
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
BRD-K08359838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64094
GSE135244_0_v_1_trdmt1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Poisoning	CTD Gene-Disease Associations	1.0	1.22306
medial habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.2811
CSFR	Kinase Library Tyrosine Kinome Atlas	1.0	95.86
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE132948,GSE132949_2_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5084-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC-19079543-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GSE169152_3_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GABPA_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB436	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.768494
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.906656
GSE92364_0_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
SC-71539 (MAGEA1)	NURSA Protein Complexes	1.0	null
AB80 (BRCA1)	NURSA Protein Complexes	1.0	null
GNL2	Pathway Commons Protein-Protein Interactions	1.0	null
NELFE_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POU2F2_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A20018680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28488
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE114992,GSE114993_9_v_6_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS 174T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
H3K36me3_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R9A-SM-2HMJ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59388
intracellular part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
CAL33	CCLE Cell Line Gene CNV Profiles	1.0	1.4968
PMC12069319-Table1.xlsx-OCAB_WT_BirA-Gene_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14307
BRD-K33454318	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44916
8305C_THYROID	CCLE Cell Line Proteomics	1.0	2.86569
BRD-A21168039	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22606
cytisine-6217	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2810-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K31844308	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37578
PMC8384902-mmc3.xlsx-MS_from_ASCL1_co-IP-GENE_Symbol_ASCL1	Rummagene Transcription Factor Associations 2026	1.0	null
BL2462 (DDX5)	NURSA Protein Complexes	1.0	null
CRCGN012_HEPG2_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09528
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of TSPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75506
biological regulation	GO Biological Process Annotations 2015	1.0	null
GTEX-U412-0426-SM-3DB9O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44277
GTEX-XGQ4-0426-SM-4AT4I	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13951
BL8108 (RAD54L2)	NURSA Protein Complexes	1.0	null
GTEX-Q2AH-1526-SM-48TZG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87665
mefloquine-1364	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Exoribonuclease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.881
core part of DTg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32011
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
Intergeniculate leaflet of the lateral geniculate complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.77452
r11 part of the trigeminal column	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.4155
HCT116	CCLE Cell Line Gene Expression Profiles	1.0	1.63846
GSE199606_3_v_4_ricin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K38209615	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24674
TAL1_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52868251	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50755
NOP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-4.96374
Lung squamous cell carcinoma_LUSC_TCGA-94-7033-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.88647
Sarcoma_SARC_TCGA-DX-A7ER-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
leaf lamina	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.89817
POU3F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26485
GTEX-WQUQ-0426-SM-3MJFU	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04471
GTEX-WXYG-2026-SM-4E3IY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99226
BRD-K99807388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04471
ATF2	ENCODE Transcription Factor Targets	1.0	null
Nr5a2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.4534
KMS27	CCLE Cell Line Gene CNV Profiles	-1.0	-2.45906
Perturb_5104_KO_Ythdc1/Dux_SRP251747	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.87522
YY1_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25470159	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08311
BRD-K43558307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25596
REST_PFSK-1_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199204,GSE211619_4_v_0_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Promastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.791
TBP_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15275_OE_Foxa1_SRP189075	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
AC-18-DC84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.463193
Dorsal tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.47682
NR2F2	ENCODE Transcription Factor Targets	1.0	null
PMC12450466-joces-138-264096-TableS2.xls-r_0_2-CEBPZ_CEBPZ	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-MT-A7BN-01A-12R-A34R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCIH2286_LUNG	CCLE Cell Line Proteomics	1.0	2.81423
orbital frontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.10545
inferior occipital gyrus, right, superior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.13722
BRD-K75900642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10855
SOX9-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFON-0226-SM-3GIKR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11317
H3K27ac_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Foxj2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.8306
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13943
frontal pole, right, superior aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.06814
Perturb_2830_OE_RAF1_SRP064353	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.75351
RT4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.73448
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferior olive, medial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.49811
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28595
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.59346
BPH-1	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.94121
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K82538319	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08322
H3K4me3_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SMAD3-30307970-HCASMC-HUMAN-CORONARYARTERY	ChEA Transcription Factor Targets 2022	1.0	null
SK-N-MC cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.795
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
primary visual cortex (striate cortex, area V1/17)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36887
CBC651 (AGAP3)	NURSA Protein Complexes	1.0	null
GTEX-TSE9-0011-R9A-SM-3DB7Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939765
Perturb_14268_OE_Mir451a_SRP305305	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	10.0038
PSMD4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.45586
BL237 (RAD17)	NURSA Protein Complexes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7725-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CRCGN013_HEPG2_24H:O04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.05628
PMC10746608-427_2023_709_MOESM5_ESM.xlsx-SOX2_partners-SOX2_known_protein_partners_according_to_BioGrid_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1	ChEA Transcription Factor Targets	1.0	null
18535662-TableS2d	GeneSigDB Published Gene Signatures	1.0	null
BL1742 (CDK7)	NURSA Protein Complexes	1.0	null
plumule	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.393819
BRD-K56658444	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0543
IRF4	ENCODE Transcription Factor Targets	1.0	null
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KA-81-AG66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.726623
GSE168602,GSE168604_2_v_6_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1493	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13346
lung	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Abdomen	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	2.3
orbital frontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.9087
GSE114992,GSE114993_4_v_2_irf5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.8115
NCIH1793	CCLE Cell Line Gene CNV Profiles	-1.0	-1.38821
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.945022
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26108750	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22533
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
tanespimycin-1166	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
rrna processing	GO Biological Process Annotations 2015	1.0	null
GTEX-UPJH-0226-SM-3GADV	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909379
parastrial preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18445
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
496100336_TCx_no dementia_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.48983
BRD-K70109334	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6977
CRCGN016_MCF10A.TP53.M_24H:C17	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.40378
GTEX-OHPM-2126-SM-3LK75	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21628
Lung squamous cell carcinoma_LUSC_TCGA-21-5787-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.938468
m1 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16728
GTEX-WXYG-2526-SM-3NB3F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22245
MYC_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventral medial nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.851008
maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	GO Biological Process Annotations 2023	1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.24385
RA-42-CM42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.21827
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A6TD-01A-51R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K16643911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10219
GTEX-TKQ1-1026-SM-4GICL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23752
mediodorsal nucleus of thalamus_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.01637
BL2745 (C1D)	NURSA Protein Complexes	1.0	null
GATA1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Small ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.773
BL2776 (NF2)	NURSA Protein Complexes	1.0	null
KAT2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28446462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43913
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUZC-1026-SM-4BOPY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922167
PMC11575453-12964_2024_1940_MOESM1_ESM.xlsx-S2_NKL_PP-Gene_GLIS2	Rummagene Transcription Factor Associations 2026	1.0	null
PMC12616242-can-24-3452_supplementary_table_s2_suppst2.xlsx-Down_bins-Down_bins_loosing_H3K27me3_in_hpMSC-EWSR1_FLI1_FLI1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE118816_0_v_1_myo1c_human	RummaGEO Gene Perturbation Signatures	1.0	null
UF-27-HS98_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.06226
apoplexy; cerebral hemorrhage; cerebral hemorrhages; intracranial hemorrhages; stroke; subarachnoid hemorrhage	GAD Gene-Disease Associations	1.0	null
BRD-K75168124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38939
AF-00-QK19_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.332904
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206516,GSE206518_3_v_4_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NC-27-AD53_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.204991
DC-70-EK34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.23104
mediodorsal nucleus of thalamus_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46914
BCL3	ENCODE Transcription Factor Targets	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.986263
CBC561 (BAT3)	NURSA Protein Complexes	1.0	null
Trypanosomoid cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.873
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6379-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BL2195 (USP4)	NURSA Protein Complexes	1.0	null
GTEX-SUCS-1926-SM-32PM3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15131
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61182411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92519
medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1306
mantle zone of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12135
CB-16-SY72_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.46523
T84	CCLE Cell Line Gene Expression Profiles	1.0	1.67246
CTBP2	ENCODE Transcription Factor Targets	1.0	null
BB-20-UU03_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.301385
ri1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.07
NEDD8	Pathway Commons Protein-Protein Interactions	1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
rc95	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.668
Fetal Kidney	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.39004
GSE244072_10_v_7_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
subcuneiform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.891356
Hemorrhage	CTD Gene-Disease Associations	1.0	1.165
Leukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
brain	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
JD-81-YX02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.455036
H3K4me1_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
lymphnode_5b	HPA Tissue Sample Gene Expression Profiles	1.0	1.07212
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.38348
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.22149
BL2512 (TLK2)	NURSA Protein Complexes	1.0	null
BRD-K23434564	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13072
BL5619 (DAXX)	NURSA Protein Complexes	1.0	null
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
KP-N-YN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE224131_3_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
BL1110 (CENPF)	NURSA Protein Complexes	1.0	null
USF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCFC1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.39265
KE-73-XV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.908664
H3K36me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K42575648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21764
CBC52 (NAT13)	NURSA Protein Complexes	1.0	null
NURR1	MotifMap Predicted Transcription Factor Targets	1.0	null
shell of SCH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.50259
Triangular nucleus of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.68897
CBC681 (GIT1)	NURSA Protein Complexes	1.0	null
THOC5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.39032
lateral habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.30891
carbarsone-1313	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SG in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.63896
CEBPB	ENCODE Transcription Factor Targets	1.0	null
mantle zone of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10193
KMRC20_KIDNEY	CCLE Cell Line Proteomics	1.0	2.0581
BA-46-YF32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.457945
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5175-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
STAT5A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
retromammillary area, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09123
non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.22544
TAL1-30185409-HPC-MOUSE-BONEMARROW-LEUKEMIA	ChEA Transcription Factor Targets 2022	1.0	null
LD-69-ZV56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.270035
H3K4me3_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC6981130-41467_2019_14235_MOESM9_ESM.xlsx-FICD_KD-Unnamed_6_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Autosomal dominant disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL1039 (RCOR1)	NURSA Protein Complexes	1.0	null
BATF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15285842	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23097
kidney diseases	GAD Gene-Disease Associations	1.0	null
uterine cervix	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
posteroventral (inferior) parietal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27761
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
retrotrapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16885
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03219
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A45Q-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K06250424	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17324
JHH6	CCLE Cell Line Gene Expression Profiles	-1.0	-1.56023
medial subhabenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.46232
Primary somatosensory area, lower limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.21252
EE-03-SG02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.203521
5557_NDUFB5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.62618
GTEX-T2IS-0426-SM-32QPE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.44168
GSE114992,GSE114993_7_v_11_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cell part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
SIN3A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-U8XE-0226-SM-4E3J3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49911
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_upreg-mouse_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE153871_0_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PRKCZ_KO_GDS4310_293_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
Salivary gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.1
EKLF-21900194-ERYTHROCYTE-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
signal transduction	GO Biological Process Annotations 2015	1.0	null
U3 snoRNA binding	GO Molecular Function Annotations 2023	1.0	null
GSE202434,GSE202438_7_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-UPJH-0126-SM-4IHLL	GTEx Tissue Sample Gene Expression Profiles	1.0	2.56592
GATA1_erythroblast_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
heart	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-1.38923
ventrolateral prefrontal cortex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.844302
membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K56520977	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.82651
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cell surface receptor signaling pathway	GO Biological Process Annotations 2015	1.0	null
famprofazone-6029	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K98749544	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13199
DA-10-ZX00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.346436
COLO-800	GDSC Cell Line Gene Expression Profiles	-1.0	-2.56441
H3K79me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K37956279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96225
NOBOX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00599185
Perturb_9704_KO_GCaMP_SRP067928	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.96496
RXRA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-2426-SM-48TDN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875932
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.15314
BL5418 (DLG5)	NURSA Protein Complexes	1.0	null
RELA	ENCODE Transcription Factor Targets	1.0	null
GB-06-BA49_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.306186
SNAI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9595
CAL851_BREAST	CCLE Cell Line Proteomics	1.0	2.38263
CBC41 (NAT10)	NURSA Protein Complexes	1.0	null
intracellular organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.80147
FB-66-UU47_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.234823
GATA1_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7815-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
dorsal lateral geniculate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.07007
H3K9ac_Stomach Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CAKI-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.50902
ventrolateral prefrontal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.05105
AC-84-QG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.525145
H3K79me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4EP-0126-SM-3P5YV	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35281
BRD-K15444511	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70263
Supramammillary nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04428
NCI-H2803	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06944
medial parabrachial nucleus,right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1636
GTEX-PWO3-0011-R2A-SM-2S1OX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26204
p3 portion of the substantia nigra pars compacta	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0279
ESR1	JASPAR Predicted Transcription Factor Targets	1.0	null
rRNA 5'-end processing	GO Biological Process Annotations 2025	1.0	null
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52172
organelle	GO Cellular Component Annotations 2015	1.0	null
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POU2F2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE86507,GSE86509_3_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE240896,GSE240899_10_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SP in caudal perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0343
RXRA	ENCODE Transcription Factor Targets	1.0	null
VD-88-MW70_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.394069
H3K36me3_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38706080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.8951
geldanamycin-1008	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE118765_1_v_5_rreb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K96075847	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.40616
Perturb_5014_OE_Prdm15_SRP064415	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	8.47547
SC-48788 (FOXG1)	NURSA Protein Complexes	1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC4090731-bjc2014262x1.xls-Sheet1-CaSig-HSF1_Positive_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.37296
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.40502
HUP-T3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K04095185	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28086
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BL4168 (DTL)	NURSA Protein Complexes	1.0	null
PMC4728380-ncomms10153-s11.xlsx-M12243-SCHUHMACHER_MYC_TARGETS_UP_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL2461 (DDX5)	NURSA Protein Complexes	1.0	null
SFN	Pathway Commons Protein-Protein Interactions	1.0	null
sulfapyridine-2538	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Duchenne muscular dystrophy (DMD)_Muscle - Striated (Skeletal) - Diaphragm (MMHCC)_GSE1026	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.38658
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
retina	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-0.852549
COLO-783	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894723
NCI-H835	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE191105_2_v_3_nat1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166944_3_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cellular macromolecule metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KLF1	ChEA Transcription Factor Targets	1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.24672
sulfamerazine-6036	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
intracellular membrane-bounded organelle	GO Cellular Component Annotations 2015	1.0	null
BRD-K35098144	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42508
BRD-K51760683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4808
NCIH2405	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65229
BL5519 (PCNT)	NURSA Protein Complexes	1.0	null
GSE110178_2_v_6_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GCT	GDSC Cell Line Gene Expression Profiles	1.0	2.13883
GSE140607_5_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
rectum	HPA Tissue Gene Expression Profiles	-1.0	-2.06114
BRD-K21416096	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05172
PMC9288051-13046_2022_2428_MOESM12_ESM.xlsx-Kasumi-1-genes_bound_by_LYL1_at_its_promoter_regions_in_AML_cell_line_Kasumi-1_LYL1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BL5763 (IRS2)	NURSA Protein Complexes	1.0	null
Anterior hypothalamic nucleus, central part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.18637
GTEX-QDT8-0011-R1A-SM-32PKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876106
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895805
DMS 454	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00303
Organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.603
protein complex	GO Cellular Component Annotations 2015	1.0	null
KMS-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.959979
IC-76-JU42_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.17458
GTEX-X4XX-0126-SM-3NMC2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.978825
KAT2A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228413_0_v_3_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
WDR36	Pathway Commons Protein-Protein Interactions	1.0	null
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.909494
dentate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.27701
CAKI-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.866299
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
7562_RRP15_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.506304
Perturb_6853_KO_PUM2_SRP273968	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.04461
ERBB2_overexpression_230_GSE14990	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.65919
GSE142210_2_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Intracellular anatomical structure	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.603
intracellular organelle part	GO Cellular Component Annotations 2015	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K35639494	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40064
Prostate adenocarcinoma_PRAD_TCGA-HC-7752-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221327_10_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
a-CLSPN (CLSPN)	NURSA Protein Complexes	1.0	null
r10 part of spinal vestibular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.11558
Kidney renal papillary cell carcinoma_KIRP_TCGA-F9-A7VF-01A-11R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ventrolateral prefrontal cortex_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14685
GSE226983_1_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
genistein-1073	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SG in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.95529
nicardipine-1600	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GABPA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CS-9665B (CASP3)	NURSA Protein Complexes	1.0	null
GTEX-WCDI-0008-SM-47JYE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05659
BRD-K19925255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54866
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5707-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MAX_C2C12_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
trochlear nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.51942
EN	COSMIC Cell Line Gene Mutation Profiles	1.0	null
piromidic acid-4575	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-TMZS-0126-SM-3DB9Q	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03545
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GATA4	ChEA Transcription Factor Targets	1.0	null
GSE218949_0_v_1_cep20_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Neuroepithelioma cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.79
KB-46-EJ60_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.894716
TF-77-DW08_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.258655
FA-36-VA24_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.670811
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4043
ATF3_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PP-0326-SM-33HC4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0355
GSE112860_5_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
bed  nucleus of stria terminalis, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.39922
ETS1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-2526-SM-2TC6D	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861215
HS 936.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.0071
GSE142588_2_v_0_cinobufagin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839467
CRCGN015_HEPG2_48H:I06	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.02825
binding	GO Molecular Function Annotations 2015	1.0	null
GSE201309_1_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ENTPD2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.11329
GSE89767_7_v_5_cebpa_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7480058-95058-2020.08.29.20182899-10.xlsx-1ModuleKeyDrivers-Target_gene_symbol_that_KD_acts_upon_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.0343
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-0011-R5A-SM-2I5EF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17392
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5702-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IO-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver Cirrhosis	CTD Gene-Disease Associations	1.0	1.03493
GTEX-PWO3-0011-R3A-SM-2I5EX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03466
ribonucleoprotein complex biogenesis	GO Biological Process Annotations 2023	1.0	null
GTEX-T6MN-2026-SM-4DM7L	GTEx Tissue Sample Gene Expression Profiles	1.0	3.17626
NY	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K81916372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94827
BL2752 (LCOR)	NURSA Protein Complexes	1.0	null
GSE132948,GSE132949_2_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF574	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30536
PMC4139969__F3	PFOCR Pathway Figure Associations 2023	1.0	null
CBC581 (KDM5C)	NURSA Protein Complexes	1.0	null
GSE240896,GSE240899_3_v_0_ccnt1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ipi1	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.462
nuclear part	LOCATE Curated Protein Localization Annotations	1.0	null
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.899659
GSE138019_4_v_5_nudt12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K16238077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53554
YY1_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.04256
GM2493	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.56677
dorsolateral prefrontal cortex_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.34968
Lung adenocarcinoma_LUAD_TCGA-55-A493-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
outer SZ in posteroinferior (ventral) parietal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.876915
PB-18-HD85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.79961
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QR-A70A-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-enclosed lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.603
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RKO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CBC194 (ERCC6L)	NURSA Protein Complexes	1.0	null
GTEX-X88G-0004-SM-47JZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.865499
GSE225869_2_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATF3-27146783-CHIP-SEQ-COLON-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-38-4625-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A4JB-01A-51R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YD-49-HM53_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.407109
PMC7754672-JEM_20201699_DataS1.xlsx-Myc_targets-SCHUHMACHER_MYC_TARGETS_UP_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K70237115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11999
BL2155 (USP34)	NURSA Protein Complexes	1.0	null
BRD-K70924576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27687
GTEX-S341-0526-SM-4AD5U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.838424
NCR1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00488219
GTEX-QEG5-0226-SM-2I5GI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34564
Insect labium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.886
MYC_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_id_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
urinary bladder	HPA Tissue Protein Expression Profiles	1.0	1.04464
Perturb_3736_KD_TMED9_SRP180007	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.17093
BRD-K79732056	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76261
Eye disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.859
H3K9me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
15832406-Table3	GeneSigDB Published Gene Signatures	1.0	null
BL5913 (NUCKS1)	NURSA Protein Complexes	1.0	null
CBC193 (ERCC6L)	NURSA Protein Complexes	1.0	null
GTEX-NPJ8-0011-R2a-SM-2TC6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19349
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153871_5_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
periventricular stratum of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13871
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853348
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
RNA binding	GO Molecular Function Annotations 2023	1.0	null
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
GSE149903_0_v_7_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC8384902-mmc2.xlsx-5_POU2F3_high_subtype-Gene_Symbol_POU2F3	Rummagene Transcription Factor Associations 2026	1.0	null
HEC50B	CCLE Cell Line Gene CNV Profiles	1.0	1.96986
SW13	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	4.19882
endometrium_4b	HPA Tissue Sample Gene Expression Profiles	1.0	0.854247
PMC12356310-mmc1.xlsx-Rep_3_Control_and_MTR4_KD-Gene_Name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02017
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03669
trichostatin A-1561	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Prelimbic area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.38788
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.162
CADM1_Deficiency_GDS2027_722_mouse_Testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80399
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06086
MYC-22102868-CA46-HUMAN-BLOOD-BURKITTSLYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
GSE153836_14_v_5_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CF-65-GU65_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.377693
ribosomal small subunit biogenesis	GO Biological Process Annotations 2023	1.0	null
CRCGN016_MCF10A.TP53.M_24H:A20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1014
Anterior hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27126
posteroventral (inferior) parietal cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1213
BRD-A39407481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3592
outer SZ in ventromedial extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.993957
sno(s)RNA-containing ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.152
Anteroventral periventricular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.1773
intracellular membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Kidney Diseases	CTD Gene-Disease Associations	1.0	1.31536
GATA3	ENCODE Transcription Factor Targets	1.0	null
IRF4_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01278504	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.81911
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01281780	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23573
SAP30	ENCODE Transcription Factor Targets	1.0	null
GTEX-OHPL-2026-SM-3TW8R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02821
NCI-H28	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BL1242 (MAML2)	NURSA Protein Complexes	1.0	null
GSE223540_0_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_9384_KD_Cdk19_SRP197255	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
NCIH1435	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34306
Magnocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15262
Perturb_6509_KD_ZNF131_SRP100164	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.12457
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SC-28676 (SATB1)	NURSA Protein Complexes	1.0	null
female reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.0758
CRCGN015_MCF10A_48H:B23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.43869
GSE199204,GSE211619_4_v_2_glutamine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.37544
CRCGN011_HEPG2_24H:N04	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.6046
SRF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SC-101092 (ITGB3BP)	NURSA Protein Complexes	1.0	null
H3K4me3_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pyrantel-2097	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CC-03-PW00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.275204
BRD-K77801455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46144
intracellular non-membrane-bounded organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045461
high-affinity iron permease complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.781
SKN-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X88G-0126-SM-47JZ3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991068
Sarcoma_SARC_TCGA-DX-A3UD-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CCT6A	Hub Proteins Protein-Protein Interactions	1.0	null
EGR1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JC-63-DO70_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.399077
Perturb_4779_KD_Trim24/Trp53_ERP016337	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.22362
Perturb_4710_KO_Sox9_ERP109172	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.25131
Female inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.696
Perturb_4317_KO_Fmn2_SRP109283	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.10636
AB-71-CI37_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.390969
BRD-K74506898	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.29843
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cytoplasmic part	LOCATE Predicted Protein Localization Annotations	1.0	null
BRD-K82662168	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34187
BRD-K04928505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66745
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.85318
YT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
rectum_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.51009
NCI-H2052	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.45407
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCVADR RES	BioGPS Cell Line Gene Expression Profiles	1.0	0.953752
GSE165647_2_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
DC-47-KV62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.214798
BRD-K87044635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.3625
KNS-62	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.98455
Perturb_10879_Mut_Nlrp3_SRP230804	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.063
HCC4011	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72719
ATF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5206
NCIH716	CCLE Cell Line Gene CNV Profiles	1.0	1.41915
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875659
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DCP1A-22483619-HELA-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GU-A763-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SUPT20H	ENCODE Transcription Factor Targets	1.0	null
BRD-K76351135	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37007
H3K27ac_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EK-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
h zone	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.16953
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	57.2935
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04698
COLO-684	GDSC Cell Line Gene Expression Profiles	1.0	1.48916
CAPAN-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869499
NCI-H1793	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.65152
Procyclic form	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.735
FOXA1	ENCODE Transcription Factor Targets	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL5829 (PHF6)	NURSA Protein Complexes	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6II-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82521339	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85158
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K52833964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17905
MA-58-RR04_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.319564
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11761043-media-2.xls-r_0_2-CEBPZ_CEBPZ	Rummagene Transcription Factor Associations 2026	1.0	null
GSE112760,GSE112767_1_v_3_ddx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TAL1_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-W5WG-0002-SM-3NMDN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12001
GTEX-X5EB-2226-SM-46MW4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.85984
Bed nuclei of the stria terminalis, anterior division, dorsomedial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1074
BD-49-MD69_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.245171
GTEX-RVPU-0011-R7A-SM-2XCAB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.27873
dorsal preisthmic part of periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6517
CD-05-PU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.588197
striatum_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.76261
SG in posterior frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.53066
BL2730 (SIN3A)	NURSA Protein Complexes	1.0	null
POLR2A_MEL cell line_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MED1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.43357
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OP-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A09988375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1759
SHPRH	Pathway Commons Protein-Protein Interactions	1.0	null
19962670-TableS3	GeneSigDB Published Gene Signatures	1.0	null
OVCA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.91177
NCI-H2081	GDSC Cell Line Gene Expression Profiles	-1.0	-1.82017
Caov-4	GDSC Cell Line Gene Expression Profiles	-1.0	-1.43253
Lung adenocarcinoma_LUAD_TCGA-86-8279-01A-11R-2287-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE246053_1_v_2_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MDA-MB-453	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19O-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE196540,GSE196542_4_v_5_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
organelle part	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K23299829	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08024
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A76905089	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37141
SIX5_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL1873 (NCOA6)	NURSA Protein Complexes	1.0	null
DA-20-VR86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.766809
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE171269_1_v_4_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BL3555 (SUPT5H)	NURSA Protein Complexes	1.0	null
primary visual cortex (striate cortex, area V1/17)_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.77733
GTEX-T8EM-0126-SM-4DM5R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.65309
COV504	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869499
BRD-K97569931	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0793
BRD-K46561246	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.92986
Spinocerebellar ataxia type 2	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.469
TE5	CCLE Cell Line Gene CNV Profiles	1.0	1.6476
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nuclear lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
GSE220520_6_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-A89681034	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02769
Acute Myeloid Leukemia_LAML_TCGA-AB-2824-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
medial habenular nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.62013
GSE240027,GSE240030_5_v_2_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_5981_KD_XRN2_SRP271175	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.92134
GTEX-QV44-1926-SM-2S1RF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.864222
BRD-K97368902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70055
Perturb_203_KD_Id1/ld3_SRP193147	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.31924
BL5906 (NFRKB)	NURSA Protein Complexes	1.0	null
GTEX-R55E-1326-SM-48FCR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19208
SOD1	MSigDB Cancer Gene Co-expression Modules	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CBC32 (POLDIP3)	NURSA Protein Complexes	1.0	null
BRD-K65464642	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26335
intracellular organelle part	LOCATE Curated Protein Localization Annotations	1.0	null
Cystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.092
EFM-192B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.838223
Lung adenocarcinoma_LUAD_TCGA-62-A46P-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PWN1-0126-SM-2I3FK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14146
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
protein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.043465
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
dorsal lateral geniculate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0916
NCI-H1435	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76303
BRD-K54862370	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04469
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-O5YT-0126-SM-48TBW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33642
GSE242647_2_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
bed nucleus of the stria terminalis, medioseptal division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10389
Noc4p-Nop14p complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.201
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ribonucleoprotein complex	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIMM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29528
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38141
BRD-K85951787	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.52796
gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
lateral posterior nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05353
CTCFL_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12821819-40478_2025_2173_MOESM9_ESM.xlsx-Supplementary_Table_3a-Supplementary_Table_3A_List_of_Top_1000_Genes_with_the_Highest_Stochasticity_by_JSD_in_the_ATRT-MYC_Subtype_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.92243
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14563
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19148
prostate	HPA Tissue Protein Expression Profiles	-1.0	-1.04297
Ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.017
GSE164757,GSE164759_4_v_0_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.243616
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6823-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
GSE142430_2_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sarcoma_SARC_TCGA-X6-A7W8-01A-21R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
betamethasone-1590	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WOFM-1726-SM-3MJFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840252
CRCGN015_MCF10A.TP53.M_24H:A16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.30315
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K05639803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23237
CDK9	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.33072
posterior (caudal) superior temporal cortex (area 22c)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.03544
CREM-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Erythroleukemia cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
ceftazidime-1721	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
UF-27-HS98_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.463213
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OF-05-CB18_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.754108
GSE198380_0_v_1_phgdh_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ATF3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DAP3	MSigDB Cancer Gene Co-expression Modules	1.0	null
SRF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC	ENCODE Transcription Factor Targets	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-HV-A7OL-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K69569958	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15658
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GATA1_erythroblast_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LOVO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.896308
BRD-K87803080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19844
Perturb_1051_KD_ESRRA_SRP267236	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39642
A704	CCLE Cell Line Gene CNV Profiles	1.0	1.56378
lm9	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.755
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SW1783	Achilles Cell Line Gene Essentiality Profiles	1.0	1.28501
EKLF-21900194-ERYTHROCYTE-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2785-01A-01R-0851-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K24220535	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01741
KA-29-AB08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.6232
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WF-96-ME07_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.329895
Central linear nucleus raphe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52846
BT-20	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.08721
GSE210842_3_v_1_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.603
BRD-K11502669	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.93219
superficial stratum of DgSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14082
REST_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3282_KD_RORA_SRP117629	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
ACTL6A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.03895
MAX_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CF-50-QK79_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.387727
GSE201042_2_v_3_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AD-50-WA90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.338543
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.07473
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC6488577-41598_2019_43010_MOESM2_ESM.xlsx-Proteingroups_MBD3_pos-Gene_names_MBD3	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ribonucleoprotein complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.085773
H3K9ac_Mesenchymal Stem Cell Derived Adipocyte Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HMGN3	ENCODE Transcription Factor Targets	1.0	null
BRD-K17886576	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.01819
GSE234637_1_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K75983763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24248
NCI-H1581	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.34528
Ribosome biogenesis in eukaryotes	KEGG Pathways 2026	1.0	null
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.953606
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.2338
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54903703	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23397
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.60111
SRF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.05513
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92852
BL2795 (TRIM24)	NURSA Protein Complexes	1.0	null
POLR2A_kidney_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 741	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00303
josamycin-2034	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-RU72-0726-SM-46MUW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.991408
Perturb_10306_KO_Pkd2_SRP128475	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.01829
CCRT CEM	BioGPS Cell Line Gene Expression Profiles	-1.0	-2.16817
septal nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.41897
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FF-8046-01A-11R-2213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE125153_2_v_0_bcl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BL2459 (DDX17)	NURSA Protein Complexes	1.0	null
intracellular non-membrane-bounded organelle	LOCATE Curated Protein Localization Annotations	1.0	null
BRD-K12709183	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.444
Perturb_4813_KO_Apex1_SRP193096	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.2085
XBP1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	34.2965
NCI-H226	GDSC Cell Line Gene Expression Profiles	-1.0	-1.72722
GSE168602,GSE168604_2_v_1_selumetinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TA-34-CK62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.489957
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.952864
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32492
BRD-K64268886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.76826
Elytron	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.325
SIX5_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE126762_1_v_0_klf15_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE183251_1_v_5_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_12083_KO_Trp53_DRP003641	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.10053
Perturb_14909_KO_Peg10_SRP167954	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.3625
BRD-K96170781	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18062
GTEX-NPJ8-0126-SM-2YUNR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23191
BRD-K12531686	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34164
GSE128099,GSE128159_3_v_2_gemcitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
XKR8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.13484
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51272331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30717
BL2133 (SSBP3)	NURSA Protein Complexes	1.0	null
BRD-K46701848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29106
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.66772
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11989
TP53-23651856-MEF-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
Polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.14
CB-16-SY72_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.513908
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
rostral subdivision of paraventricular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.10112
Kidney renal papillary cell carcinoma_KIRP_TCGA-P4-A5E6-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ELK4_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRO-0126-SM-2YUN4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.962878
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.00531
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-FD-A3SN-01A-12R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-2126-SM-3NB1P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.9234
fibrillar center	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.947808
BRD-K86587289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14846
NCIH1105	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34665
BRD-K48255349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45213
BL2286 (ZC3H13)	NURSA Protein Complexes	1.0	null
FD-20-OG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.27681
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.1779
BL4381 (NASP)	NURSA Protein Complexes	1.0	null
Dinoflagellate sulcus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.516
DC-47-KV62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.456066
BRD-K28619632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01555
BRD-K64970964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03313
CA-26-UY62_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.298671
BL463 (RBM39)	NURSA Protein Complexes	1.0	null
lymphoblastic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.252261
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_6_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2JK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NRF1	ENCODE Transcription Factor Targets	1.0	null
PMC4407272-elife06857s001.xls-MITF_partners_CAF-MITF_partners_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
496100333_FWM_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.66435
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Paraventricular hypothalamic nucleus, magnocellular division, posterior magnocellular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.0021
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MYBBP1A	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K13719101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.74493
SAOS2	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.28548
KA-51-CQ55_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.404482
CEBPB_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hyperplasia	CTD Gene-Disease Associations	1.0	1.31746
BL4214 (THRAP3)	NURSA Protein Complexes	1.0	null
GTEX-OIZG-0726-SM-33HBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11715
FHL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.04672
r8 part of linear nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.22519
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL4W-0011-R9a-SM-2I3G1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.850821
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAV0-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A21891180	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74474
GSE86507,GSE86509_7_v_1_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K19608763	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20899
GTEX-X585-0002-SM-46MVA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06504
GTEX-XAJ8-0826-SM-47JY6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.967573
GTEX-OIZI-0126-SM-3NB13	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31774
PMC7430827-12864_2020_6933_MOESM4_ESM.xlsx-Sheet1-Additional_file_4_Table_S4_A_list_of_3_062_genes_containing_locus_where_only_KD_had_non-synonymous_SNPs_compared_to_other_duck_breeds_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PMC8174725-ppat.1009603.s006.xlsx-neg_nsp3-ZSGvs_Untr-nsp3-ZSG_PATZ1	Rummagene Transcription Factor Associations 2026	1.0	null
BL2262 (DOCK9)	NURSA Protein Complexes	1.0	null
BL6324 (ABL1)	NURSA Protein Complexes	1.0	null
BL2671 (FANCB)	NURSA Protein Complexes	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A-61603	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44887
BRD-K39692099	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.82256
BRD-K98720112	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39274
BL1582 (E4F1)	NURSA Protein Complexes	1.0	null
Perturb_17534_KD_C1QBP_SRP270881	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE248770_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NUDC	Pathway Commons Protein-Protein Interactions	1.0	null
GSE160817_7_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K89459607	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43135
Adrenocortical carcinoma_ACC_TCGA-OR-A5L9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DF-00-BU08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.701851
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dorsolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.45995
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.31791
GTEX-N7MT-0011-R4a-SM-2I3G9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03841
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-0011-R10A-SM-2I5GC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08059
intermediate stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2848
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.39015
PMC12069319-Table1.xlsx-OCAB_p34_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
CBC2152 (RFWD3)	NURSA Protein Complexes	1.0	null
ramifenazone-5879	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
lung	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-2.16354
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SF-01A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
roof plate of p2 (epithalamic roofplate)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.80578
BL1685 (BUB3)	NURSA Protein Complexes	1.0	null
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.8906
GTEX-Q2AI-1326-SM-2S1PL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01659
BRD-A19766589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05436
H3K4me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ASH2L-23239880-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GABPA_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
15735024-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
planum temporale, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.44372
leaf epidermis	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.912653
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XGQ4-1526-SM-4AT6H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0057
Gata3	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	40.6682
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1	Pathway Commons Protein-Protein Interactions	1.0	null
MDA-MB-468	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894723
CURI complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.318
HPBALL	CCLE Cell Line Gene CNV Profiles	-1.0	-1.95031
EPI-2461-1 (RPA2)	NURSA Protein Complexes	1.0	null
GRM	CCLE Cell Line Gene Expression Profiles	1.0	2.00847
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CE-15-YU05_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.218122
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.845605
H3K4me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
YY1_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.214576
CRCGN011_HEPG2_24H:G02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14805
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.832777
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39717
RD-90-OY66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.614451
Small-subunit processome, Utp13	InterPro Predicted Protein Domain Annotations	1.0	null
POLR2A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CREB3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.8827
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.50867
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939942
Lung adenocarcinoma_LUAD_TCGA-NJ-A4YI-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0011-R1A-SM-2TC6N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03698
ZNF770	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.473
DC-51-WE27_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.676882
Perturb_3742_KO_Cd274_SRP215305	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.79996
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Cerebral lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HBL-100	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.913993
GSE181821_1_v_3_mov10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF274_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
indisulam	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2323
superficial stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05008
Lung adenocarcinoma_LUAD_TCGA-75-7025-01A-12R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SLR25	CCLE Cell Line Gene CNV Profiles	1.0	1.86967
HL60	CCLE Cell Line Gene Expression Profiles	1.0	1.53585
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.971321
caudal ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.05243
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
outer CP in ventrolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.869623
CTV-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.058877
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
membrane-bounded organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
RELA_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K59030325	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0105
motor nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.989507
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8096-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
endonucleolytic cleavage of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	GO Biological Process Annotations 2025	1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63083
BL2607 (HDAC1)	NURSA Protein Complexes	1.0	null
VCAN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01144
JD-44-KF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.82638
PMC12069319-Table1.xlsx-OCAB_WT_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE157894_2_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K79159743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4353
Sarcoma_SARC_TCGA-DX-A7ET-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-A7IG-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63155804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19038
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K13090434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34935
Perturb_8304_KD_SSB_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.39316
A498	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.910642
Reservosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.757
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5100-01A-01R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BD-49-MD69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.73682
ELK1	ENCODE Transcription Factor Targets	1.0	null
GSE98964_1_v_4_tet2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BL6238 (TRERF1)	NURSA Protein Complexes	1.0	null
GTEX-XMD1-2826-SM-4AT5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0071
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-96-7544-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
GSE185922_1_v_2_riok2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
4994_METTL16_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.522591
BRD-K20530300	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07852
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90563
ChIP_ESRRB_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
posteroventral (inferior) parietal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.21026
BL1872 (NCOA6)	NURSA Protein Complexes	1.0	null
DA-35-DU85_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.556982
BL5778 (TNKS1BP1)	NURSA Protein Complexes	1.0	null
GSE207122_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K44061011	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59315
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.51315
TMEM104	Pathway Commons Protein-Protein Interactions	1.0	null
NFIC_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL6690 (KDM5D)	NURSA Protein Complexes	1.0	null
HB-06-WU12_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.301764
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
smooth muscle	HPA Tissue Protein Expression Profiles	-1.0	-1.04297
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M9-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KON	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.19886
GSE88819_7_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striohypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01953
SS18L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26958
GTEX-X4EO-2926-SM-4E3JH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.840819
Intracranial Hemorrhages	HuGE Navigator Gene-Phenotype Associations	1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67913
BRD-K67390084	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.7077
Other source	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.4
PMC6109294-13045_2018_650_MOESM1_ESM.xlsx-ST12_KEGG_JURKAT-Unnamed_11_KLF6	Rummagene Transcription Factor Associations 2026	1.0	null
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
Perturb_13593_OE_Lef1_SRP134386	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.60423
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22055
BRD-K89744662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03907
ABC-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
endocrine gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ELK3-25401928-HUVEC-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
THAP1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-VUSH-0004-SM-3P61T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2039
BRD-K68663367	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92277
SP4	ENCODE Transcription Factor Targets	1.0	null
A549_SB431542_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137172
H3K9ac_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-75-6214-01A-41R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pineal gland	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0511
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.869262
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QS-2126-SM-3NMCF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7511
BRD-K96249452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37775
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-415	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23797
periventricular stratum of PO2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03996
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K26423054	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.36374
Lateral septal nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53777
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A4OZ-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventral tegmental area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.927182
NCIH1876	CCLE Cell Line Gene Expression Profiles	-1.0	-1.61744
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10325
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ELK4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.0814
PMC10061014-Table5.XLSX-C_vs_LD-Table_S5c_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_DEX_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
BL6197 (NR2F6)	NURSA Protein Complexes	1.0	null
AGS	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.13863
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1184	CCLE Cell Line Gene Expression Profiles	-1.0	-2.52056
MYC_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KE37	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40918
GSE128076_2_v_3_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KARPAS-45	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Liver	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.6481
BRD-K88960810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69791
layer I of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.33742
KMS-27	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.3249
BRD-K20470077	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03343
ncrna processing	GO Biological Process Annotations 2015	1.0	null
nucleus of the central acoustic tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.21366
GSE211177,GSE211178_4_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Prostate	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.03393
BL2593 (RPL7A)	NURSA Protein Complexes	1.0	null
cerebellar cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.893663
BL2838 (UIMC1)	NURSA Protein Complexes	1.0	null
Nervous system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.029
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS-114	GDSC Cell Line Gene Expression Profiles	1.0	1.63617
Bladder Urothelial Carcinoma_BLCA_TCGA-CF-A47W-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE173232_4_v_3_sf3b1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GABPA_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FD-62-ZB67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.275906
BRD-K55518911	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33016
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A5PC-01A-11R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Las1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.626
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5SH-06A-11R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Lung adenocarcinoma_LUAD_TCGA-97-A4M1-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K79me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE114992,GSE114993_7_v_5_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cardiovascular	GAD High Level Gene-Disease Associations	1.0	0.293278
10029_ZC3H8_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.536613
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32732
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92569554	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15107
5470_NAT10_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.520117
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Periventricular region	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.01953
H3K4me3_G1E-ER4_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
IFRD2	Pathway Commons Protein-Protein Interactions	1.0	null
HMEL	CCLE Cell Line Gene Expression Profiles	1.0	2.98926
H3K4me1_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE162276_2_v_3_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WFON-2126-SM-3LK7O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12149
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A10T-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3115	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
b-lymphocyte	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.092677
Perturb_14955_OE_PRDM1_SRP287780	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	1.59349
butoconazole-6288	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BL993 (MORC2)	NURSA Protein Complexes	1.0	null
DDB1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE201217_4_v_6_usf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CDC42	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1458
GTEX-S95S-1126-SM-4B64E	GTEx Tissue Sample Gene Expression Profiles	1.0	2.2979
BL1035 (KDM1)	NURSA Protein Complexes	1.0	null
BRD-K57323824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12324
butirosin-2518	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Skin	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.103
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
BRD-K29200961	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0595
DA-66-OE69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.66483
organelle	LOCATE Predicted Protein Localization Annotations	1.0	null
Preribosome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	3.0
Retinal cone	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.72
doxycycline_mus musculus_gpl2872_gse33875	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WYJK-0126-SM-3NMAB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18322
GSE112860_5_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K14117311	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07882
GSE234289_4_v_1_rfx6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TP63-30713093-EPITHELIAL-HUMAN-TONGUE-SCC	ChEA Transcription Factor Targets 2022	1.0	null
GSE217776,GSE217829_2_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
GTEX-WVLH-0011-R7A-SM-3MJFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.956152
Perturb_5475_KO_Sox9_SRP375106	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.86329
TD-29-IN36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.1199
SPI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIMELESS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18408
GSE235066_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-S33H-0126-SM-4AD62	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3879
NCI-H1048	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.30284
PMC4139969__F3	PFOCR Pathway Figure Associations 2024	1.0	null
GSE200159_1_v_0_setd4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HIV - Human immunodeficiency virus infection_T lymphocyte_GSE2504	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	0.6515
SW403	CCLE Cell Line Gene CNV Profiles	1.0	1.38068
GSE242647_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
neostigmine bromide-5335	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K66511507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03455
lateral group of nuclei, right, ventral division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.921091
GSE169691_1_v_2_saha_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-U8XE-0126-SM-4E3I3	GTEx Tissue Sample Gene Expression Profiles	1.0	2.60322
GSE235066_7_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XUYS-0002-SM-47JXL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851409
HCC12	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.91692
SUMO2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE211931_0_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBP_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
rosiglitazone-1071	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.936426
IZ in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.895049
pontine nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.44325
BRD-K64137284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17101
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
SETD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.46133
ATF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213588_10_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
inner SZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.909579
NCI H226	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.887359
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0511
DLD1	BioGPS Cell Line Gene Expression Profiles	1.0	0.858365
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE120612_7_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE129370_2_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
colon	HPA Tissue Protein Expression Profiles	1.0	1.04464
GSE216043_10_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.958666
JA-26-YQ32_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.340052
PMC12069319-Table1.xlsx-OCAB_p35_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.85698
JAK2_druginhibition_167_GSE38335	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.28298
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-7058-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11031
CREB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUP85	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF449	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45576
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930861
BRD-K24271020	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22819
BRD-K79816111	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.02008
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5835-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164757,GSE164759_4_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
FBXL12	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05386
SH4_SKIN	CCLE Cell Line Proteomics	1.0	2.62573
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.35716
BRD-K10748141	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16734
GTEX-UTHO-0011-R3A-SM-3GIK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.938584
GTEX-RU72-0926-SM-2TF6B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.28164
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-Q1-A5R2-01A-11R-A28H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K46149455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04105
sarcoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.400453
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intermediate stratum of Mam	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71029
PMC10746608-427_2023_709_MOESM5_ESM.xlsx-NR3C1_partners-NR3C1_known_protein_partners_according_to_BioGrid_NR3C1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135400_1_v_0_kdm1b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_7425_KD_RBFOX2_SRP045481	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.0546
EGR1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_H1 Derived Neuronal Progenitor Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K14868348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88306
HC-38-KI38_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.217276
ROCK2_knockdown_157_GSE34769	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.50159
GSE203308_4_v_3_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
MED9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.58361
PMC11908325-media-2.xlsx-Table10_MR-Unnamed_7_NR3C2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AA-22-UI44_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256961
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.75714
HEB	MotifMap Predicted Transcription Factor Targets	1.0	null
GSE205976,GSE205978_3_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE159049_1_v_0_sox2_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.05102
GSE179880_1_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6781492__F3	PFOCR Pathway Figure Associations 2024	1.0	null
PC-14	GDSC Cell Line Gene Expression Profiles	1.0	2.40402
NCI-H920	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.40264
open-angle glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.859
dorsal juxtacommissural pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5775
SP2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TP63-22573176-HFKS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
PPIL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.10792
MYOG	ENCODE Transcription Factor Targets	1.0	null
mantle zone of RMa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13565
GSE169205_3_v_5_sirt5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02258
POLR2A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HSF1_01_178	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.59979
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84697
BRD-K49103797	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6705
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
occipital neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18856
TCF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.88851
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5596_KD_HNF4A_SRP201581	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.68497
GB-46-CK08_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.770606
RUNX1_KO_GDS1511_251_mouse_Embryos at E12	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Arsenic	CTD Gene-Chemical Interactions	1.0	null
COLO783	Achilles Cell Line Gene Essentiality Profiles	1.0	1.17362
GTEX-OHPN-0011-R11A-SM-2I5FM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1509
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
cerebellar cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27093
Disease of anatomical entity	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
PMC9601604-NIHMS1841143-supplement-SuppTable-2.xlsx-FOXO3-specific_targets-FOXO3-specific_targets_1218_FOXO3	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K28774883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50392
liver	GTEx Tissue Gene Expression Profiles	-1.0	-1.21137
BRD-K92349794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10164
ATF3	ENCODE Transcription Factor Targets	1.0	null
BL1355 (FUS)	NURSA Protein Complexes	1.0	null
BRD-K20329507	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37903
PMC12486367-Supplementary_Data2.pdf-19-THYN1_THYN1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K85527716	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31715
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JA-23-QE71_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.212403
BRD-K47261271	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24895
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63098
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4782_KD_Trim24/Trp53_ERP019861	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.22362
Pancreatic adenocarcinoma_PAAD_TCGA-IB-A7M4-01A-11R-A36G-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD2_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN017_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.86675
BL8517 (CKAP2L)	NURSA Protein Complexes	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COPI-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.049
amygdaloid complex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.70793
HCMV_24Hour_20173022_GSE17948	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.93514
BL844 (PRKD2)	NURSA Protein Complexes	1.0	null
GSE216273,GSE216292_0_v_6_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BL2498 (DOT1L)	NURSA Protein Complexes	1.0	null
BRD-K11297155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49057
lm4	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.802
BT474	Achilles Cell Line Gene Essentiality Profiles	1.0	1.03969
CHD2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE213996_1_v_0_fhl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
chr16_1985252_T_C_b38	GTEx eQTL 2025	1.0	1.35274
ventral tuberomammillary nucleus, intermediate part (histaminergic)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.58007
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3B	ChEA Transcription Factor Targets	1.0	null
GTEX-PSDG-0626-SM-2S1OE	GTEx Tissue Sample Gene Expression Profiles	1.0	0.871593
r1 part of dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01476
Ventral pallidus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.00965
GTEX-U8XE-0326-SM-3DB8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51746
BRD-K06519744	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.64861
SBC-5	GDSC Cell Line Gene Expression Profiles	-1.0	-1.5732
GSE213588_9_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PWP2	Pathway Commons Protein-Protein Interactions	1.0	null
RBBP4	Pathway Commons Protein-Protein Interactions	1.0	null
NCIH2347	CCLE Cell Line Gene CNV Profiles	-1.0	-1.57156
RFX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7113
periventricular stratum of JcPL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50852
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12981	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.95125
small-subunit processome	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
GSE183113_1_v_0_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32943057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.39419
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.48754
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03822
TE-15-RO34_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.256646
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR3C1_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
THAP1	ENCODE Transcription Factor Targets	1.0	null
preoptic telencephalon	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06218
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
cellular_component	LOCATE Curated Protein Localization Annotations	1.0	null
iproniazid-2125	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BL4941 (TRIM3)	NURSA Protein Complexes	1.0	null
CRCGN015_MCF10A.TP53.M_24H:A08	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.13392
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AP-01A-12R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K92825272	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30185
CBC751 (USP9X)	NURSA Protein Complexes	1.0	null
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67484361	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10952
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC1	ENCODE Transcription Factor Targets	1.0	null
BL922 (CUL9)	NURSA Protein Complexes	1.0	null
SIX5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K87269010	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.36696
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.33354
SIX5	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-719	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.13208
GSE42805,GSE42811_2_v_3_cocaine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
bl-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.33048
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC12405659-CTM2-15-e70437-s001.xlsx-Supplementary_Table_5-BioGrid-interaction_protein_with_MYC_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
HNT34	Achilles Cell Line Gene Essentiality Profiles	1.0	2.13268
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
OVCAR-4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.930861
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NANOG_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular signal transduction	GO Biological Process Annotations 2015	1.0	null
GTEX-S7PM-0011-R5A-SM-3NM8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45319
hippocampus (hippocampal formation)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.83238
caudal portion of VFC (area 44)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.46104
BL1050 (C11orf30)	NURSA Protein Complexes	1.0	null
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE206516,GSE206518_3_v_7_ptdss2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
ATF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_5353_KO_Dux_SRP201141	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.34852
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CRCGN008_HEPG2_24H:H01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.81025
BRD-K26321439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16098
PAX5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHY	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.0056
HDAC6	ENCODE Transcription Factor Targets	1.0	null
GTEX-NL3H-0011-R7a-SM-2I3G5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.12083
BRD-K87982677	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13295
MLL1/2 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.714
inferolateral temporal cortex (area TEv, area 20)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.868969
H3K4me1_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EB-A5KH-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CBC682 (GIT1)	NURSA Protein Complexes	1.0	null
SC-50347 (PIAS4)	NURSA Protein Complexes	1.0	null
nucleus	LOCATE Curated Protein Localization Annotations	1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CUL4B	Pathway Commons Protein-Protein Interactions	1.0	null
Heart disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
GTEX-TML8-1926-SM-32QOS	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869258
testis_7e	HPA Tissue Sample Gene Expression Profiles	1.0	2.34556
GSE239844_8_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HCC1806	GDSC Cell Line Gene Expression Profiles	1.0	2.17744
RKO	Achilles Cell Line Gene Essentiality Profiles	-1.0	-2.02367
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01114
HeLa	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.7178
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
BL7647 (MAP3K7)	NURSA Protein Complexes	1.0	null
ELK4	ENCODE Transcription Factor Targets	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-94-A4VJ-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Hepatomegaly	CTD Gene-Disease Associations	1.0	1.16799
BL3800 (PALB2)	NURSA Protein Complexes	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_MEL cell line_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
RERF-LC-OK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07582
GSE153871_4_v_2_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_3980_KD_CDK8_SRP057708	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.57496
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL5576 (CEP110)	NURSA Protein Complexes	1.0	null
BRD-K99048639	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35626
GSE149903_6_v_1_myd88_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_14202_KD_KLF5_ERP117894	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.16152
PMC11827247-41065_2025_387_MOESM5_ESM.xlsx-Sheet_1-Only_ESR_ESR1	Rummagene Transcription Factor Associations 2026	1.0	null
Sarcoma_SARC_TCGA-DX-A8BZ-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of POH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02963
GSE120612_4_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_Adipose Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Sarcoma_SARC_TCGA-QQ-A5V9-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SRF	ChEA Transcription Factor Targets	1.0	null
cerebellum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.50446
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37415
H3K79me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SUM52PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.16666
parathyroid gland	HPA Tissue Protein Expression Profiles	-1.0	-1.04297
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912138
Perturb_10853_KO_Mkp1_SRP169858	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-14.8199
GSE223908,GSE223909_1_v_6_serpinb3_human	RummaGEO Gene Perturbation Signatures	1.0	null
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8327-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28238
Nucleolus	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	4.0
PMC12289921-41467_2025_62099_MOESM5_ESM.xlsx-MI-2-80-Gene_Symbol_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K93051667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.09317
NCI-H1693	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.58138
Brain disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.273
BRD-K07855097	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34737
mammillary body, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.950587
BRD-K17893805	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.49836
BRD-K90594901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.07844
orbital frontal cortex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.17651
IL17RC	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00513614
GTEX-SNMC-1026-SM-4DM7K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79192
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.11386
Lung squamous cell carcinoma_LUSC_TCGA-56-8304-01A-11R-2326-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PWP2	Hub Proteins Protein-Protein Interactions	1.0	null
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.86767
pretectal region	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.31513
GTEX-P44H-0011-R4A-SM-2XCEW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40545
BRD-K85235446	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1378
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.54609
TA-34-CK62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.296347
Liver hepatocellular carcinoma_LIHC_TCGA-G3-AAUZ-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BL2777 (NF2)	NURSA Protein Complexes	1.0	null
JARID1B-DAIN-22020125-ESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
AB-09-EA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.383537
H3K9ac_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.86139
BA-84-WN26_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.30305
BRD-K65178566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96149
GSE221577_4_v_5_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hippocampus (hippocampal formation)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.865677
H3K79me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CFB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00534935
NANOG	ENCODE Transcription Factor Targets	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.44974
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.13997
intracellular organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
BRD-K16976282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.9548
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX9-25088423-EMBRYONIC-GONADS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
MZ in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.937375
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.882779
TAL1-20566737-PRIMARY FETAL LIVER ERYTHROID CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
NCIH1651	CCLE Cell Line Gene CNV Profiles	1.0	1.34753
GTEX-WEY5-0226-SM-3GIKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05042
IRF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Ubiquitin E3 ligase (AHR, ARNT, DDB1, TBL3, CUL4B, RBX1)	CORUM Protein Complexes	1.0	null
KCNK15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0565
GSE140200_1_v_3_trim59_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdaloid complex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.55148
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE104022_3_v_7_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65B-01A-12R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
skin	HPA Tissue Gene Expression Profiles	1.0	1.46838
TYRO3	Kinase Library Tyrosine Kinome Atlas	1.0	97.35
MALME3M	CCLE Cell Line Gene CNV Profiles	1.0	2.66354
GSE133516_0_v_1_kat7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
isoetarine-3451	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
YY1	MotifMap Predicted Transcription Factor Targets	1.0	null
Intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.603
III, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.8189
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17683
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03817
outer CP in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09096
Intracellular organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.603
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.46288
GSE137818_3_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BL2502 (REST)	NURSA Protein Complexes	1.0	null
GSE213588_8_v_7_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.979589
Ribonuclease MRP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.753
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X261-0011-R7A-SM-4E3JJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03786
ELK4	JASPAR Predicted Transcription Factor Targets	1.0	null
RAGE_knockout_268_GDS3755	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-3.53845
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	GO Biological Process Annotations 2025	1.0	null
testis_7d	HPA Tissue Sample Gene Expression Profiles	1.0	1.35962
IF-87-AU84_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.29946
BRD-K61621331	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13444
HSC-3	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Olig2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	16.8727
GSE63048_11_v_5_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
snoRNA binding	GO Molecular Function Annotations 2023	1.0	null
SPI1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-16-5p	MiRTarBase microRNA Targets	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F1	ChEA Transcription Factor Targets	1.0	null
rectum_8c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.37878
GTEX-QEG4-0226-SM-2S1PY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.83145
GABPA_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
496100338_HIP_probable Alzheimer's disease_no TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.48375
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE242290_3_v_0_glutathione_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BL6998 (ZKSCAN1)	NURSA Protein Complexes	1.0	null
SUPT20H_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-A6I0-11A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Medial septal complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.11781
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE190534,GSE190536_0_v_3_cyclophosphamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CAKI2	CCLE Cell Line Gene CNV Profiles	1.0	1.46807
GSE119564_1_v_3_zfp217_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.873164
GTEX-X261-0011-R6B-SM-4E3J8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21228
EPI-1962-1 (PRKD2)	NURSA Protein Complexes	1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.17448
BRD-K87853964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34456
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.824278
Perturb_16917_KD_Maf1_SRP375944	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	7.60526
Prostate adenocarcinoma_PRAD_TCGA-FC-A6HD-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_liver_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG8-1926-SM-4LVM1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6092
intracellular non-membrane-bounded organelle	GO Cellular Component Annotations 2023	1.0	null
Perturb_1277_KO_Ptpn2_SRP108032	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.9609
small-subunit processome	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE124375_13_v_12_chd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82405
hypoglossal nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.33605
GTEX-WFG8-1826-SM-4LVM4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97996
GTEX-R55F-1226-SM-2TF59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02197
RBM22	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0123
BRD-K03476091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60808
parietal neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32303
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040359
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.31317
GB-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K17441474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68816
DD-65-SA37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.64885
BRD-K60216304	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22916
PMC11103890-mmc3.xlsx-ZZZ3_interactors_ESC-2-Gene_names_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828445
IGR37_SKIN	CCLE Cell Line Proteomics	1.0	5.49971
WM278	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Perturb_6764_KO|KD_SERPINE2_SRP103746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.32021
PMC6078963-41467_2018_5311_MOESM5_ESM.xlsx-48h_KD_UP_Vs_ATAC-mgi_database_human_gene_AR	Rummagene Transcription Factor Associations 2026	1.0	null
C32TG	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958536
ATF3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Thyroid	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	0.882509
NCOR1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K04980212	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53235
Rheumatoid arthritis disease specific synovial fibroblast	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.505
EPI-2416-1 (HMGB3)	NURSA Protein Complexes	1.0	null
ribonucleoprotein complex	GO Cellular Component Annotations 2015	1.0	null
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16418
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K14207150	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16584
CREB1	ENCODE Transcription Factor Targets	1.0	null
BRD-K18136154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77166
CE-04-PX35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.204107
CF-87-AS90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-3.01538
Adrenocortical carcinoma_ACC_TCGA-OR-A5J5-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHEK2_knockdown_84_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.82183
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18037
membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
GTEX-UTHO-0011-R2A-SM-3GIKC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05131
lm13	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.155
lateral tuberal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.84426
THAP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
cellular process	GO Biological Process Annotations 2015	1.0	null
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K56618252	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15204
BRD-K19046167	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04101
G120	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21363
GTEX-W5X1-0826-SM-3GILN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.865957
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3383-01A-02R-1325-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in thalamic region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.890757
t-UTP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.906
GTEX-XUJ4-0004-SM-4BOQE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19368
H3K4me3_Pancreatic Islets	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K43926323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41859
thalidomide-1411	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-X4EP-0726-SM-3P5YJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908161
nuclear lumen	GO Cellular Component Annotations 2023	1.0	null
GTEX-WHSB-1326-SM-3LK6W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.87989
ribosomal small subunit biogenesis	GO Biological Process Annotations 2025	1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K42508877	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19576
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231648_1_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.885378
epidermal cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.254902
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
PAICS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27017
GSE129389_0_v_5_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XYKS-1426-SM-4BRUO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13693
BL1074 (AURKB)	NURSA Protein Complexes	1.0	null
SF539	GDSC Cell Line Gene Expression Profiles	-1.0	-1.45939
rRNA 5'-end processing	GO Biological Process Annotations 2023	1.0	null
SIN3A_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28983467	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03939
NCI-H209	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.3581
SIN3B-21632747-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
testis	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Main olfactory bulb, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08086
p1 portion of the paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25294
RXR-22158963-LIVER-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BA-56-QV45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.17136
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Brain Hippocampus Middle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
CRCGN012_HEPG2_24H:K01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.1486
496100324_FWM_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.50525
NHK cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.736
BL3513 (KDM4A)	NURSA Protein Complexes	1.0	null
BRD-K06790927	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87762
BL1164 (SNIP1)	NURSA Protein Complexes	1.0	null
BRD-K12493093	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.70502
HES7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.8438
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PU.1-20513432-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
layer VI of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.02623
superficial stratum of r6BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16937
AA-52-JS03_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.413001
BRD-K54453373	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00815
MAFK_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A58803929	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30744
GSE120612_7_v_2_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Enhanced S-cone syndrome	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.442
STAT1::STAT2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	46.6742
medial mammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.71029
GTEX-X4XY-0011-R8A-SM-46MVC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69318
Lung adenocarcinoma_LUAD_TCGA-78-7163-01A-12R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.24367
H3K4me3_G1E-ER4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CAL-85-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.2641
ZE-45-CG69_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.34461
Perturb_14573_KO_EP300_SRP336466	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.17756
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K60454848	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18091
90S preribosome	GO Cellular Component Annotations 2025	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL3H-0011-R3a-SM-2I3GL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.7443
LGR4	Pathway Commons Protein-Protein Interactions	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-G9-6347-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-V955-1926-SM-4KL1L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66687
BRD-K15675930	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29349
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839092
GSE128076_1_v_3_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Prostate adenocarcinoma_PRAD_TCGA-J4-A67M-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SART1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.60909
BRD-K82927098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33137
GTEX-S7SF-1626-SM-3K2AY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.17309
NCI-H187	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23943
Perturb_14201_KD_HNF4A/GATA6_ERP108557	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	7.123
estrone-4993	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-O5YT-0008-SM-4E3IQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900916
H3K4me3_H1 Derived Mesenchymal Stem Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.50253
GSE202434,GSE202438_4_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P78B-1626-SM-2S1O1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.992892
nucleolus	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
TMEM231	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4697
GSE199606_1_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.828445
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary auditory cortex (core)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.89171
Perturb_10782_Mut_Nlrp3_SRP230804	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
nucleolus	LOCATE Curated Protein Localization Annotations	1.0	null
nuclear periphery	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.257289
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.41744
GTEX-WXYG-2326-SM-4E3I6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829748
PYGO2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00517416
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4981-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_8132_KD_EIF4A3_SRP013565	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	4.34963
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-85-A4QR-01A-11R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RVPU-0011-R3A-SM-2XCAE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33289
BRD-K60850201	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37819
NCIH2081	CCLE Cell Line Gene Expression Profiles	-1.0	-1.51644
GSE198165,GSE198166_7_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
fulvestrant_homo sapiens_gpl570_gse22533	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE68156_3_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SIN3B-21632747-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
ATF2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12909843-41467_2026_68388_MOESM4_ESM.xlsx-fig3g-up-regulated_gene_expression_in_OTX2-KO_8CLCs_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF3C2-35216376-H9-HUMAN-BONEMARROW-LYMPHOMA	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12952
CTCF_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153757,GSE153758_0_v_2_ftsj1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.73597
paracentral lobule, posterior part, right, bank of cingulate sulcus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.28884
PMC10061014-Table5.XLSX-C_vs_L-Table_S5a_Results_of_gene-wise_analysis_of_cd-ASE_depending_on_LPS_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GABPA_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary	HPA Tissue Protein Expression Profiles	-1.0	-1.04297
ATF3_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD7	ENCODE Transcription Factor Targets	1.0	null
AKT1_OE_GDS2308[_473_mouse_heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
BL326 (RFX5)	NURSA Protein Complexes	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-KK-A7AW-01A-11R-A32O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ACT-1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.995
milrinone-5856	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
SRF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862788
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
LCLC-97TM1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24206
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.10767
GTEX-QDVN-2426-SM-2S1Q4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35682
GTEX-NPJ8-1626-SM-2HMIY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19258
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.88557
IRF4_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K20236423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.18085
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.80395
BL5117 (ILK)	NURSA Protein Complexes	1.0	null
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MKN-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.32456
endocrine gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050729
BRD-K32839286	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.87165
Lung adenocarcinoma_LUAD_TCGA-86-A4JF-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GABPA_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney Chromophobe_KICH_TCGA-KL-8328-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EE-98-PF86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.626156
EP300_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SC-6954 (BRCA1)	NURSA Protein Complexes	1.0	null
organic cyclic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
BRD-K71007902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22369
MPND	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K76997656	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51197
small-subunit processome	GO Cellular Component Annotations 2023	1.0	null
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
ANKRD13B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.29828
BL4782 (AKT1S1)	NURSA Protein Complexes	1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
dihydrostreptomycin-1391	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.82735
Perturb_15544_KD_Pten_SRP199649	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
TAF7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
smooth muscle	HPA Tissue Gene Expression Profiles	-1.0	-1.01708
BL5495 (RAD18)	NURSA Protein Complexes	1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.34654
HCC515	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00303
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_CH12.LX_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN008_HEPG2_24H:K09	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.0989
ARID3A	ENCODE Transcription Factor Targets	1.0	null
FF-86-NH56_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.263443
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
soft tissue	HPA Tissue Protein Expression Profiles	-1.0	-1.04297
PMC7480058-95058-2020.08.29.20182899-10.xlsx-1ModuleKeyDrivers-Target_gene_Ensembl_that_KD_acts_upon_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PD-74-VS77_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.290274
SW 780	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00035
skeletal system	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052332
H3K4me3_Chondrocytes from Bone Marrow Derived Mesenchymal Stem Cell Cultured Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
pterigoid muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46754
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Spikelet	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.011
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL3431 (CRTC1)	NURSA Protein Complexes	1.0	null
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959317
PMC9174882-EMMM-14-e15816-s004.xlsx-MYC_GeneSigs-DANG_REGULATED_BY_MYC_UP_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL3463 (CASC5)	NURSA Protein Complexes	1.0	null
dorsal subdivision of VLC	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.992914
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_11758_KO_Tlr3/Mavs_SRP114764	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.1498
Nucleus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.603
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34318928	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14065
BRD-K55538850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40152
Mafg	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.4116
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K38853406	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14053
GSE121809_1_v_0_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
USP36	Pathway Commons Protein-Protein Interactions	1.0	null
Perturb_15758_KO_Adipor1_SRP339096	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.82439
GSE112860_3_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128076_2_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
preribosome, small subunit precursor	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.193
fulvestrant-6955	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JEKO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33491
GTEX-S7SF-0426-SM-3K2B7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05039
BRD-K31210612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.38991
intracellular non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBC31 (POLDIP3)	NURSA Protein Complexes	1.0	null
intermediate portion of DFC (area 9/46)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.967953
NCIH524	CCLE Cell Line Gene Expression Profiles	1.0	1.79859
BRD-K99125195	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23492
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ncrna metabolic process	GO Biological Process Annotations 2015	1.0	null
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
MYC-19079543-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
SC-67022 (SPDEF)	NURSA Protein Complexes	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDAMB468	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.727028
ZNF707	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	55.7243
GSE188570,GSE188571_3_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5890-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF-26484167-CHIP-SEQ-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POU2F2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM5B	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_Rectal Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
ITSN2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE112860_0_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_15280_OE_Foxa1_SRP189075	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-6.87849
AF-99-HA02_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.688387
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBK-0126-SM-2YUND	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16564
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NFIC	ENCODE Transcription Factor Targets	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30261
Magnetosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.13
temporal muscle trigeminal motor cell group	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17527
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KA-75-LP02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.593285
BL1601 (TSC1)	NURSA Protein Complexes	1.0	null
COLO-205	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.58346
SIX5_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2405	CCLE Cell Line Gene CNV Profiles	-1.0	-1.41592
CRCGN015_MCF10A.TP53.M_24H:G12	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.1308
BL6872 (ALMS1)	NURSA Protein Complexes	1.0	null
H3K4me3_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
nucleic acid binding	GO Molecular Function Annotations 2015	1.0	null
AE-42-HT01_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.291981
IPC-298	COSMIC Cell Line Gene Mutation Profiles	1.0	null
MYC_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K79me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RT4	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34375
GSE149139_1_v_0_carm1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43388
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SUCS-1326-SM-4DM5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.66044
ITPKC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.25076
imatinib_homo sapiens_gpl96_gds3049	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LIAS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59108
GTEX-OXRN-1326-SM-3LK5V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32999
BRD-K86453556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41187
organelle	LOCATE Curated Protein Localization Annotations	1.0	null
JHOM1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.74616
methapyrilene-1588	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
WE-43-PZ45_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.09828
plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.094934
GTEX-UTHO-0011-R4A-SM-3GIJP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1131
AD-06-OB47_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	1.17172
SIN3A	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-5085-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SPSB1	Hub Proteins Protein-Protein Interactions	1.0	null
HuP-T4	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.67538
HCC2185	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.12448
intracellular organelle part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.052916
BL2798 (CCNA1)	NURSA Protein Complexes	1.0	null
BL2755 (LCOR)	NURSA Protein Complexes	1.0	null
p3 portion of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.19354
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TIMMDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06437
MET_knockout_251_GDS3148	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.84605
USF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.2628
GTEX-V955-2026-SM-3GAFA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874687
amygdaloid complex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13853
macromolecular complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.046894
CHD1	ENCODE Transcription Factor Targets	1.0	null
BRD-K63394284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16378
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.971467
GSE241701_2_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221327_4_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149075_2_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
JD-44-KF86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.453995
Ascl2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	34.815
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211177,GSE211178_0_v_1_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_CH12.LX_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PHB1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.18692
Glaucoma	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.859
RPS20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.90636
DU-145	GDSC Cell Line Gene Expression Profiles	-1.0	-2.18438
GSE148262,GSE150691_3_v_2_hdlbp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2A	MotifMap Predicted Transcription Factor Targets	1.0	null
YY1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55D-1126-SM-48FEB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.892136
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.74941
BRD-K91585756	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.4802
SYK_druginhibition_152_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.40256
Bed nucleus of the anterior commissure	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91149
USP15	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.51671
BC-54-ON71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.285313
GSE181821_1_v_4_mov10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NUP85	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.42674
GM1600	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.946808
ATF3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KAT2A	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K48782834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45902
Prostate adenocarcinoma_PRAD_TCGA-HC-A6AL-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
doxepin-6337	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FAM72D	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.02845
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4198
lufenuron	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4094
BATF	ENCODE Transcription Factor Targets	1.0	null
BL2442 (RNF4)	NURSA Protein Complexes	1.0	null
GSE153836_11_v_2_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GJA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06647
salivary gland	HPA Tissue Protein Expression Profiles	-1.0	-1.04297
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
diagonal part of septum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10087
TAF1_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7156
thioridazine-6989	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SIN3A_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM28_02_63	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.60095
GTEX-S7SE-0126-SM-2XCD5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21487
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34062
STAT1	ENCODE Transcription Factor Targets	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEF2A	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-A6M8-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_6785_KD_USP42_ERP121305	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.74526
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BL239 (RAD17)	NURSA Protein Complexes	1.0	null
medial superior olive	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.06442
BRD-K24396733	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31313
BRD-K73183447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02986
periventricular stratum of SeDg	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10389
valproic acid-1639	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BL2750 (SNW1)	NURSA Protein Complexes	1.0	null
ED-33-YZ72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.20595
BL5515 (FAM129B)	NURSA Protein Complexes	1.0	null
GAL3ST1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38584
MMGT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15822
GSE137818_5_v_6_brca2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.16964
GSE81193_3_v_2_irf3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GB-73-QS80_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.13327
DA-20-VR86_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.211735
ventrolateral prefrontal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27792
NCI-H2722	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.86697
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5989-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
1212_CAST_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.53136
GABPA_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4PQ-1626-SM-2HMKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47852
BL2765 (HNRNPU)	NURSA Protein Complexes	1.0	null
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-REY6-0126-SM-48FDT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.88539
ZNF354C	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6875
BRD-K45612428	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26733
PPM1G	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01879
gastrointestinal system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.041458
GSE199606_3_v_4_csf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K60729758	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56347
BRD-K75989234	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57146
GSE209898,GSE209899_0_v_1_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
KDM4A	ENCODE Transcription Factor Targets	1.0	null
H3K9ac_Colon Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K02927989	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45492
SMC3_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBED-2026-SM-4AT5D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.686
BRD-K47658117	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6159
GSE102505_1_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
pimozide-1562	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC2279	CCLE Cell Line Gene CNV Profiles	1.0	1.70252
NCIH1048	CCLE Cell Line Gene CNV Profiles	-1.0	-2.09218
IPC-298	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
29-13 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.057
BRD-K03254663	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1407
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05353
MYC_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45296
GSE129370_0_v_1_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
chr16_1975764_A_G_b38	GTEx eQTL 2025	1.0	1.51765
VCAP	Achilles Cell Line Gene Essentiality Profiles	1.0	1.02419
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_15131_KO_Mettl3_SRP363779	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
BRD-K12043227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26597
STAT3	ENCODE Transcription Factor Targets	1.0	null
whole body	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.215341
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.950653
HCFC1	ENCODE Transcription Factor Targets	1.0	null
whole plant	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.095108
g-protein coupled receptor signaling pathway coupled to cgmp nucleotide second messenger	GO Biological Process Annotations 2015	1.0	null
TCF12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.962967
Main olfactory bulb, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69378
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8148-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_11955_KD_Phf23_SRP248452	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.7592
GATA1_MEL cell line_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-QU-A6IM-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14705
ATM_knockout_16_GDS1544	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.41519
NELFE	ENCODE Transcription Factor Targets	1.0	null
PARP1	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K71982936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11191
iPS-18 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.03753
Sarcoma_SARC_TCGA-DX-A23T-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
WD40 repeat, conserved site	InterPro Predicted Protein Domain Annotations	1.0	null
Perturb_7269_KO_ALKBH3_SRP064738	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.39349
skin_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.7943
Pheochromocytoma and Paraganglioma_PCPG_TCGA-W2-A7H7-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K07588901	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17641
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978245
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.826913
primary somatosensory cortex (area S1, areas 3,1,2)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.876185
STAT3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESRRA	ENCODE Transcription Factor Targets	1.0	null
BL2555 (UHRF1)	NURSA Protein Complexes	1.0	null
FGFR1_mutant_25_GDS4046	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.96972
BL2438 (PUS1)	NURSA Protein Complexes	1.0	null
ETS1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCAR8	BioGPS Cell Line Gene Expression Profiles	1.0	1.33689
GSE225869_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE166944_0_v_2_eif4b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AB-92-GP61_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.8661
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IB-33-TE51_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.0866
BE-79-QU25_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.261456
0297417-0002B-6902	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K87275815	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22872
SMC3_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.27352
SIN3A	ENCODE Transcription Factor Targets	1.0	null
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJMC-0008-SM-4IHKK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.90388
RMUGS	CCLE Cell Line Gene Expression Profiles	1.0	1.42422
viscus	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050634
GTEX-OOBK-2126-SM-3LK5T	GTEx Tissue Sample Gene Expression Profiles	1.0	2.94399
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.91119
BRD-K56716645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00864
pivampicillin-2945	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-OIZH-0126-SM-2HMIS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00743
DB-73-BC12_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.214008
Perturb_6763_KO|KD_SERPINE2_SRP103746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-7.93297
NIHOVCAR3	CCLE Cell Line Gene Expression Profiles	1.0	1.4634
DC-51-WE27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.305215
Heschl's gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.01606
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PU.1-20176806-MACROPHAGES-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE183335,GSE183351_1_v_2_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE162276_5_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-PQ-A6FN-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GF-35-IT27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.706838
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.881056
EIF4A3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.08506
MKK7	Kinase Library Tyrosine Kinome Atlas	1.0	95.62
TRIM28	ENCODE Transcription Factor Targets	1.0	null
GSE202284,GSE202289_7_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K93677460	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16141
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27562
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCOR2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.73138
GTEX-RUSQ-2126-SM-47JXK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.80063
BRD-K81293413	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12676
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Penis_Foreskin_Keratinocyte_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.32376
gata1_15860665_megakaryocytes_lof_mouse_gpl1261_gds1245	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.136675
928 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.955813
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IFT52	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32121
FOS	ENCODE Transcription Factor Targets	1.0	null
GTEX-XXEK-2226-SM-4BRUM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22481
SPIB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.6001
Edinger-Westphal nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.0467
BRD-A64849281	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61216
GTEX-NPJ8-0011-R1a-SM-33HCB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80958
liver carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.164786
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23797
Perturb_15128_KO_Mettl3_SRP363779	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
inner CP in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.950487
RBBP7	Pathway Commons Protein-Protein Interactions	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2H1-01A-11R-A180-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE241622_1_v_0_ythdc2_human	RummaGEO Gene Perturbation Signatures	1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.76303
ribosome biogenesis	GO Biological Process Annotations 2023	1.0	null
GTEX-VUSG-0126-SM-4KL1X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.944923
PML	ENCODE Transcription Factor Targets	1.0	null
EPI-2698-1 (APBB1IP)	NURSA Protein Complexes	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HM7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
EED	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPK5-0226-SM-3GAEV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848455
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A4ZP-01A-12R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LOXIMVI	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.05712
BL1921 (KIAA1967)	NURSA Protein Complexes	1.0	null
GSE240027,GSE240030_5_v_3_atrx_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94801
CA-68-KG29_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.5609
SPI1-22790984-ERYTHROLEUKEMIA-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K14ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE179031_0_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K52152765	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54899
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.852681
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NKM-1	GDSC Cell Line Gene Expression Profiles	-1.0	-1.67278
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.887074
GSE129389_0_v_6_tropifexor_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
E2F6_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Colonic Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_10147_KO_FAM122A_SRP235545	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	10.9663
prednisone-1978	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CREB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CAL-72	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.7633
PMC10824666-43018_2023_699_MOESM2_ESM.xls-Suppl_Table_S4-AM-1882_AUC_vs_Gene_Expression_PRISM_Breast_and_Ovarian_Cancer_Cell_lines_n_58_PRDM6	Rummagene Transcription Factor Associations 2026	1.0	null
A704	CCLE Cell Line Gene Expression Profiles	-1.0	-1.65952
BL7869 (RAPGEF2)	NURSA Protein Complexes	1.0	null
Bed nuclei of the stria terminalis, anterior division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03829
GTEX-WFG8-0726-SM-3GILP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09862
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE143462_0_v_1_omipalisib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_Duodenum Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BL2292 (BTBD12)	NURSA Protein Complexes	1.0	null
A361	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.957321
PcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.30175
XPO7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0917
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
Perturb_10316_KO_Cox10_SRP155323	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.79606
ribonucleoprotein complex biogenesis	GO Biological Process Annotations 2025	1.0	null
superficial stratum of r7Lim	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15525
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.167
BRD-K96258717	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.05812
outer CP in (rostral) midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.56731
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPIC-1626-SM-4IHKT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.939409
Lung adenocarcinoma_LUAD_TCGA-78-7535-01A-11R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsomedial hypothalamic nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.979449
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12653
GSE110440_1_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_10 mos_M_12977	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.76173
RPL30	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38296
Lung adenocarcinoma_LUAD_TCGA-78-7166-01A-12R-2066-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TMMY-1126-SM-4DXSX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29001
POLR2A_Raji_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUVEC	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.919123
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Septofimbrial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20267
TAL1_erythroblast_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A45014336	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26138
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BRD-K59870481	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23094
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
KARPAS299	CCLE Cell Line Gene CNV Profiles	1.0	2.25999
FD-91-OK66_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.427733
BRD-K27458941	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18117
GSE193541_0_v_2_nifurtimox_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K82107155	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41846
Lung adenocarcinoma_LUAD_TCGA-49-4514-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC2157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04526
BRD-K13941175	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.88155
superficial stratum of PSPa	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0881
hypocotyl	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.390421
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
HSPA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.3646
GSE202434,GSE202438_12_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.409
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE240439_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
heart	GTEx Tissue Gene Expression Profiles	-1.0	-0.831785
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AKT1_Activation - 2 week induction_GDS2308_717_mouse_Heart	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
NABP1	Hub Proteins Protein-Protein Interactions	1.0	null
hsa-miR-34a-5p	MiRTarBase microRNA Targets	1.0	null
KD-68-JH25_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.262652
GSE202434,GSE202438_15_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
CRCGN013_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.09729
Lung adenocarcinoma_LUAD_TCGA-97-7547-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
496100340_TCx_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.52771
BL2731 (SIN3A)	NURSA Protein Complexes	1.0	null
GSE86507,GSE86509_4_v_5_hoxb7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsal thalamus_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.32818
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.924778
GSE214183_1_v_0_phf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K26631178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.0092
NOMO1	Achilles Cell Line Gene Essentiality Profiles	1.0	2.36085
BL2289 (BTBD12)	NURSA Protein Complexes	1.0	null
CEBPB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBC572 (ESPL1)	NURSA Protein Complexes	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-G6-A8L6-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X88G-0326-SM-47JZ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14999
NR3C1_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H522	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.2564
ICMT	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2583
DA-85-SU90_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.237151
SA1-27219007-CHIP-SEQ-ERYTHROID-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_Fetal Brain	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NELFE_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE125153_1_v_3_bcl3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K66838902	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54096
rna binding	GO Molecular Function Annotations 2015	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.33262
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.040397
ATRIP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03802
superficial stratum of r1BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06238
GTEX-O5YW-0126-SM-3LK6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34964
JUND_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
deptropine-5118	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
granular component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.914376
PMC12586162-41593_2025_2050_MOESM3_ESM.xlsx-Supplementary_Table_7-ELK4_unique_ELK4	Rummagene Transcription Factor Associations 2026	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
GSE186440,GSE186443_0_v_5_daxx_human	RummaGEO Gene Perturbation Signatures	1.0	null
ChaGo-K-1	GDSC Cell Line Gene Expression Profiles	1.0	1.5618
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE227698_5_v_0_g0s2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.37683
GLI3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.4174
Mesothelioma_MESO_TCGA-SH-A7BH-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NDUFA13	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27078
BRD-K17300786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.6384
Liver Neoplasms	CTD Gene-Disease Associations	1.0	1.46595
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-RY-A83Y-01A-11R-A36H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZMIZ1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC193	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.00303
GTEX-R55C-1426-SM-48FED	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79408
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05274
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1882	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
perifornical nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.979379
chlorphenamine-6773	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RAD21_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_3766_KD_lincDUSP_SRP111736	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.65147
BL5549 (DEK)	NURSA Protein Complexes	1.0	null
GSE143212_1_v_2_bleomycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.948173
SIX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H1_Derived_Mesenchymal_Stem_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-0.933407
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NCIH1092	CCLE Cell Line Gene Expression Profiles	-1.0	-1.9022
OCI-AML5	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.93669
GTEX-NPJ8-0011-R7a-SM-2HMJV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.845567
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.783913
CC-17-JL38_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-4.56986
GTEX-N7MS-0011-R8a-SM-2YUMK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.960525
BRD-K72351789	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20745
plant embryo	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.388535
tissues, cell types and enzyme sources	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.249329
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
JVM-2	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.41292
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
COTL1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.32848
GSE230174_0_v_1_glycerol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HTK	CCLE Cell Line Gene Expression Profiles	1.0	1.93963
U251	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.48563
H3K27ac_Mobilized CD34 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K16681480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29976
BRD-K20043699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.0228
Limbic system	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
DBTRG05MG	CCLE Cell Line Gene CNV Profiles	-1.0	-3.21049
STK25	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SCA1_Knock-in_GDS1756_232_mouse_Cerebellum tissue - 12 weeks of age	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
IL6ST	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00666861
BRD-K23956364	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53187
male reproductive gland	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
NCI-H196	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04633
r10 part of gigantocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10406
CRCGN010_HEPG2_24H:K07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.46558
PMC12439337-thnov15p9091s1.pdf-59-ENSG00000106689_LHX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K14763154	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.05285
CADM1_KO_GDS2026_301_mouse_testis	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Autosomal dominant polycystic kidney disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.3
GSE229973_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC10203545-Table_4.xlsx-LM7_underrepresented-DMRTA1_DMRTA1	Rummagene Transcription Factor Associations 2026	1.0	null
H3K9ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69918256	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10638
GSE143994_0_v_1_ythdf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K93590856	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47063
HS 578T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.14661
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.834394
nucleolus	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.172468
SRF_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12069319-Table1.xlsx-OCAB_p40_BirA-Gene_Symbol_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
BL2393 (CDT1)	NURSA Protein Complexes	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
outer SZ in posteror frontal cortex (motor cortex)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.855098
BL5941 (WNK1)	NURSA Protein Complexes	1.0	null
GTEX-OHPN-0011-R2A-SM-2I5FB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62975
GTEX-NPJ8-0011-R4a-SM-2HML3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15451
TRIM21	Hub Proteins Protein-Protein Interactions	1.0	null
medial part of the lateral habenular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.34118
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5469-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
r2 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.3051
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.20905
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
maturation of ssu-rrna from tricistronic rrna transcript (ssu-rrna, 5.8s rrna, lsu-rrna)	GO Biological Process Annotations 2015	1.0	null
methyldopa-1619	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
NR1H4::RXRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7387
CORL24	CCLE Cell Line Gene Expression Profiles	-1.0	-2.36614
SPI1	ChEA Transcription Factor Targets	1.0	null
DB-21-FY75_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.733143
GI-ME-N	COSMIC Cell Line Gene Mutation Profiles	1.0	null
OB olfactory fiber layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.63558
PMC3419980-leu201249x2.xls-RUNX1-ETO_siRE_ChIPSeq_peaks_ge-gene_name_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
BL3118 (PPP4R2)	NURSA Protein Complexes	1.0	null
BRD-K10148216	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28427
BHLHE40_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K46400317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14018
GTEX-QLQW-1026-SM-447A9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53637
AF-00-QK19_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.22371
SLR25	CCLE Cell Line Gene Expression Profiles	1.0	1.86082
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70823
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.09078
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
143B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.952496
preribosome	GO Cellular Component Annotations 2015	1.0	null
GTEX-WFON-0326-SM-3GIKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.93128
TAF7	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_9556_KO_IKKa_SRP111864	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
Nervous system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.273
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K42455540	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34131
GSE111385_0_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K52372795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42126
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Uterine leiomyoma_Uterus_GSE2725	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.74988
GTEX-XOTO-0726-SM-4B659	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06724
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TP53-23651856-MEFS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BL1757 (MED23)	NURSA Protein Complexes	1.0	null
GABPA_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-POYW-0008-SM-48TE4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849378
DU4475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.46735
SRF	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
BRD-K28299335	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.16671
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H1792	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.74264
BRD-K61651560	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.79513
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBC632 (AKAP13)	NURSA Protein Complexes	1.0	null
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.1648
Liver hepatocellular carcinoma_LIHC_TCGA-FV-A495-01A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
VZ in caudal hippocampal proper	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.88564
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.830237
Kidney Diseases	HuGE Navigator Gene-Phenotype Associations	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09059
Brain Lower Grade Glioma_LGG_TCGA-QH-A65X-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pyrantel-1413	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K29771129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.33711
BL8106 (AHDC1)	NURSA Protein Complexes	1.0	null
Lung adenocarcinoma_LUAD_TCGA-50-6597-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PLZ4-0926-SM-2S1OI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.900177
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35771
BRD-K32170456	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.72751
GA-59-RW04_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.20739
chlorpromazine-5214	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE119978,GSE180930_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ATF3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K79me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
GD-79-TW34_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.468609
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10364_KD_Setd2_SRP184682	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.50002
Perturb_6706_KD_ELOA_SRP314942	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.07607
BRD-K98537764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.97936
GSE165682_0_v_1_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_1446_KO_Tmem173_SRP221603	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.22358
GSE139120_1_v_0_urod_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.603
10623_ZNF774_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.600737
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAL1_erythroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD4 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_6836_KO_METTL3_SRP193002	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.64375
Perturb_6315_KO_Atp4b_SRP238545	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
SZ in subgenual cingulate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.65624
GSE163282_12_v_8_aspirin_human	RummaGEO Drug Perturbation Signatures	1.0	null
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WEY5-0426-SM-3GIKT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.856639
Epilepsy_lymphoblast_GSE7486	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.49401
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUJ4-2426-SM-4BOO3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04796
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC-18358816-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
SNU-C5	COSMIC Cell Line Gene Mutation Profiles	1.0	null
RAD23A	MSigDB Cancer Gene Co-expression Modules	1.0	null
GTEX-T5JW-0126-SM-4DM6K	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931003
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18555
GTEX-X5EB-1826-SM-4E3K8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04148
RMGI	CCLE Cell Line Gene Expression Profiles	1.0	1.87013
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.868501
anterior (rostral) cingulate (medial prefrontal) cortex_15 yrs_M_12299	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.851873
Perturb_6510_KD_ZNF131_SRP100164	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.28642
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL5747 (FKBP4)	NURSA Protein Complexes	1.0	null
blood	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.061837
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior hypothalamic area, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.91282
cell part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
BRD-K89931949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.60347
GSE235066_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_3712_KO_PIWIL1_SRP188921	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.5045
H3K4me1_MEL cell line_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE164757,GSE164759_1_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE220914_2_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
anteroventral periventricular preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.81477
GTEX-VUSG-2326-SM-4KL1U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07551
BL7502 (VPRBP)	NURSA Protein Complexes	1.0	null
Perturb_4602_KO_Mst_SRP246200	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.63875
Perturb_16314_KO_BUD31_SRP335732	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.8312
CEP78	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27223
CTNNB_Activation (deltaNB-cateninER transgenics)_GDS1560_767_mouse_Skin - 1 Day	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
LS 180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.11148
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99681648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39662
GTEX-S3XE-1726-SM-3K2AM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10065
plicamycin_homo sapiens_gpl570_gse25127	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JUN_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_1664_KO_Mir146_SRP165727	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.90546
BRD-A89947015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39854
GTEX-QDT8-0011-R5A-SM-32PKN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13806
rna metabolic process	GO Biological Process Annotations 2015	1.0	null
AC-84-QG99_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.360785
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12450466-joces-138-264096-TableS2.xls-r_0_3-CEBPZ_CEBPZ	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7724-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CTCF-33576154-HUMAN-LIVER-PROSTATECANCER	ChEA Transcription Factor Targets 2022	1.0	null
intermediate part of the arcuate nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.78147
GSE97278,GSE97280_2_v_3_nsd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Nucleolar preribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.637
CML-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
TCC-PAN2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0622
BL6202 (ESRRA)	NURSA Protein Complexes	1.0	null
MYLIP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00703952
GSE114690_2_v_0_tnfsf14_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K09376136	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41881
639-V	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T6MN-0011-R9A-SM-32QOZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21214
GTEX-QVJO-0011-R2A-SM-2S1QK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840947
90s preribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.17517
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51132
REST_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ADCY7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.09508
LU-165	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.28982
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.951488
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FA-63-WI26_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.260252
BL-3 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.27
Male inflorescence	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
GSE229671,GSE229673_3_v_1_yrdc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
vagina	HPA Tissue Protein Expression Profiles	1.0	1.04464
GSE234637_1_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RM2N-1326-SM-48FCW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60617
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-A6JE-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain ventricle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESRRB-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49771
outer SZ in posterior parahippocampal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.31939
CRCGN015_MCF10A.WT.HP_24H:J19	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.28081
BRD-K96596828	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21411
M14	GDSC Cell Line Gene Expression Profiles	-1.0	-3.53725
GTEX-UJHI-1526-SM-3DB99	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30562
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72938
lateral habenular nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.75866
Lung squamous cell carcinoma_LUSC_TCGA-34-A5IX-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K08607520	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21852
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CEBPB_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PAX5	ENCODE Transcription Factor Targets	1.0	null
PMC7817097-abb9149_Table_S2.xlsx-293T-TET2-FLAG-Table_S2_Mass_spectrometry_results_for_endogenous_SMCHD1-FLAG_in_ES_cells_and_TET2-FLAG_in_293T_cells_TET2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_MEL cell line_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
superficial stratum of PPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08468
BL2754 (LCOR)	NURSA Protein Complexes	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-S9-A6WH-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.903336
H3K4me3_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K15389388	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1196
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09979
TRIM21	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12793
KYSE-450	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0466
BRD-K47821225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.95305
spinal trigeminal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.960087
Head and Neck squamous cell carcinoma_HNSC_TCGA-QK-A6IH-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.19077
BRD-K24133768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26394
BRD-K10176883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43007
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A182-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Large ribosomal subunit	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.335
r7 portion of ambiguous motor nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15683
GTEX-QMR6-0011-R4A-SM-32PKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19018
nes	HPA Cell Line Gene Expression Profiles	-1.0	-1.08336
PMC9529122-pone.0274785.s002.xlsx-S1_Table-S1A_Table_Differentially_expressed_genes_in_HeyA8_overexpressin_ZNF521_vs_HeyA8_control_cells_ZNF521	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13792
CD-35-BD44_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.15905
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WH7G-2026-SM-3NMBL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01575
GATA1_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K95501793	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2664
CORL23	CCLE Cell Line Gene Expression Profiles	1.0	2.29607
BL533 (CCAR1)	NURSA Protein Complexes	1.0	null
central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
GSE130401_4_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
GTEX-XAJ8-1326-SM-47JYT	GTEx Tissue Sample Gene Expression Profiles	1.0	2.16954
GTEX-Q2AG-1126-SM-48U1P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.890944
MTA3	ENCODE Transcription Factor Targets	1.0	null
RABGEF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.1911
signal transducer activity	GO Molecular Function Annotations 2015	1.0	null
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.53568
Disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
GTEX-WFON-2026-SM-4LVMW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47789
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.92492
BRD-K27476515	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01459
RBBP5	ENCODE Transcription Factor Targets	1.0	null
gonad	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
WDR3	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-P4PP-2026-SM-3P61N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.995696
GABPA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBD4	ENCODE Transcription Factor Targets	1.0	null
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.66273
outer CP in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.941382
HCFC1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XXEK-1626-SM-4BRUZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961424
GSE112860_5_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K62000282	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12021
Perturb_18007_Mut_Card14_SRP260070	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	9.06992
BL2786 (PSMC5)	NURSA Protein Complexes	1.0	null
BRD-A14878925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15761
496100354_PCx_dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.20051
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Plant primordium	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.857
GTEX-PVOW-0426-SM-2XCF8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31084
GSE247862,GSE247863_0_v_5_eomes_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE154936_3_v_2_remdesivir_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MSLN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03393
Perturb_11576_KO_Zip8_SRP344283	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.19108
Lung	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
H3K79me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ChIP_JARID1A_20064375	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
VCAP	CCLE Cell Line Gene Expression Profiles	-1.0	-1.77892
preribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.701304
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28096
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12326
GSE234637_3_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HDAC1	ENCODE Transcription Factor Targets	1.0	null
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.993793
Noc complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.778
MYC-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K30173420	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05191
BRD-K44193634	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37878
GSE169152_3_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_G1E_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
U2-type spliceosomal complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.658
Cystic Fibrosis_Lung_GSE3100	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.45971
BRD-K31483891	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.4371
RKO cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	1.74776
cranium	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.130886
NCIH2066	CCLE Cell Line Gene CNV Profiles	-1.0	-2.41383
GTEX-RN64-2326-SM-48FDW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.09434
T3M4	BioGPS Cell Line Gene Expression Profiles	1.0	1.05213
H3K4me3_Stomach Smooth Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MDA-MB-231	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F1-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
BL6014 (UTP18)	NURSA Protein Complexes	1.0	null
Precancerous Conditions	CTD Gene-Disease Associations	1.0	1.16203
head and face region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.55083
dorsal part of m2A	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.65117
preoptic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08122
GTEX-XMD1-0011-R2B-SM-4AT5N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42819
Theileriasis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.636
HSC-2	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.10371
BRD-K34425773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04797
PMC8566473-41467_2021_26653_MOESM3_ESM.xlsx-SOX2_interacting_proteins-Gene_symbol_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XPVG-2126-SM-4B667	GTEx Tissue Sample Gene Expression Profiles	1.0	0.882625
ONCODG1	CCLE Cell Line Gene CNV Profiles	1.0	2.09732
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Nucleus ambiguus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27005
Perturb_6859_KD_PUM1/PUM2_SRP287793	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.18622
nucleolar part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.638861
GSE171724_4_v_5_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NE-94-VE83_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.320024
Lung squamous cell carcinoma_LUSC_TCGA-98-8020-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
striatum_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.89768
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
diazoxide-1368	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ8I-0426-SM-4BOPO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03043
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:K20	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.39848
primary visual cortex (striate cortex, area V1/17)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.883963
GSE247862,GSE247863_4_v_1_eomes_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE213715_0_v_1_iqgap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233183,GSE233187_2_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K78397696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56276
BRD-K89121101	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06004
BRD-K71460915	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.59353
BRD-K44152881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.243
BRD-K81810589	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13913
H3K4me3_G1E_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
AF-99-HA02_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.246195
gastrointestinal system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.045099
CTCF_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE220520_5_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Intracellular organelle lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.603
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6781492__F3	PFOCR Pathway Figure Associations 2023	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ovary_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.33366
GTEX-U3ZM-1626-SM-4DXSK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.74415
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.27936
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_8450_KD_NPM1_SRP230777	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.84949
GSE160817_4_v_9_slamf6_human	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of m2AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.64956
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.922043
JEKO1	CCLE Cell Line Gene Expression Profiles	1.0	1.67999
OB outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14028
receptor signaling protein activity	GO Molecular Function Annotations 2015	1.0	null
RMG-I	GDSC Cell Line Gene Expression Profiles	1.0	2.13328
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07582
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SRF-21415370-HL-1-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8832
BRD-K51956957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52115
GTEX-U3ZH-1926-SM-4DXTR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21079
BRD-K59120074	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63056
CRCGN017_MCF10A.WT.HP_24H:H07	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.71855
SU.86.86	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23797
periventricular stratum of Hb	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.1599
CAL-62	GDSC Cell Line Gene Expression Profiles	1.0	1.44874
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_CD4 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-XYKS-0002-SM-4BRWN	GTEx Tissue Sample Gene Expression Profiles	1.0	0.996458
KDM5A	ENCODE Transcription Factor Targets	1.0	null
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70275
B-cell lymphoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.773
BRD-K97339945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02925
BRD-K76135327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49725
ELF1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23670243	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.45124
LY-294002-461	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_CH12.LX_mm9_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JC-06-ED36_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.305209
Bhlha15	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	24.0317
red nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.39235
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K66179451	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37066
Flower bud	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.805
H3K79me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
JHOM2B	CCLE Cell Line Gene Expression Profiles	-1.0	-2.22863
km3	HPA Cell Line Gene Expression Profiles	1.0	1.11172
MKN45	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34525
BRD-K96164740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.89363
BRD-K18594025	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78083
KYSE-30	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869499
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1	ENCODE Transcription Factor Targets	1.0	null
rRNA processing in the nucleus and cytosol	Reactome Pathways 2024	1.0	null
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57668
GTEX-RU1J-0826-SM-46MUU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.834283
MZ2-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
COPI-coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.09
NCI-H810	COSMIC Cell Line Gene CNV Profiles	1.0	4.51153
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95155
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.72599
10663_ZNF830_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.582161
NSRP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.53909
retromammillary area, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12318
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69914820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.13258
EGR1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1	JASPAR Predicted Transcription Factor Targets	1.0	null
rectum	HPA Tissue Protein Expression Profiles	1.0	1.04464
BRD-K97711917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23243
Lymphosarcoma cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	2.127
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Intracellular membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.603
inferolateral temporal cortex (area TEv, area 20)_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.57116
POLR2A	ENCODE Transcription Factor Targets	1.0	null
Hoxa13	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.3973
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46984
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL7041 (NFKB2)	NURSA Protein Complexes	1.0	null
BRD-K44856541	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49251
Pheochromocytoma and Paraganglioma_PCPG_TCGA-XG-A823-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
molecular transducer activity	GO Molecular Function Annotations 2015	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.39376
GATA1_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-BF-A5ER-01A-12R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
m2 part of paranigral nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07105
Nuclear lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.603
GABPA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial part of r8B	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26181
BRD-K41189799	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52951
dorsal raphe nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.44883
stratum lacunosum-moleculare of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.953791
non-membrane-bounded organelle	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
BL2132 (RBM15)	NURSA Protein Complexes	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-5185-01A-01R-1426-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
lm5	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.651
BRD-K37282009	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.70826
SLC27A2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.07795
blood	GTEx Tissue Gene Expression Profiles	-1.0	-0.85525
GSE223540_2_v_3_anxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
preoptic alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05008
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSN1	GDSC Cell Line Gene Expression Profiles	1.0	1.47808
breast cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.053354
STAT5A	ENCODE Transcription Factor Targets	1.0	null
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K21695872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05881
19525976-SuppTable5a	GeneSigDB Published Gene Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_36 yrs_M_12302	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.00485
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EK-A2RK-01A-11R-A18M-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GA-28-SS67_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236198
prostate gland	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	-1.0	-0.978245
AC-47-YZ27_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.203438
SW684	COSMIC Cell Line Gene Mutation Profiles	1.0	null
NALM-6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.29714
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC-28411283-MDA231-LM2-4175-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K64823749	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.072
Perturb_3806_KO_Ptpn2_ERP124267	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.657
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
endometrium_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.65005
GSE245134_2_v_3_atg5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CBC192 (ERCC6L)	NURSA Protein Complexes	1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05253426	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22411
macromolecular complex	GO Cellular Component Annotations 2015	1.0	null
GTEX-XPT6-1626-SM-4B655	GTEx Tissue Sample Gene Expression Profiles	1.0	1.57118
GTEX-QMR6-0011-R7A-SM-32PKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14019
BRD-K36002293	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24122
BRD-K12226398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.61222
EGR1	ENCODE Transcription Factor Targets	1.0	null
GTEX-XUJ4-0226-SM-4BOP8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850086
NCIH1944	CCLE Cell Line Gene Expression Profiles	-1.0	-1.49206
LRRC20	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.29787
GTEX-Q2AI-1226-SM-48U14	GTEx Tissue Sample Gene Expression Profiles	1.0	1.67511
B-lymphocyte	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.133
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K58220566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.38628
HC-92-HE59_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.48518
BRD-K13275816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05157
FD-91-OK66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.445982
PMC10943832__F5	PFOCR Pathway Figure Associations 2024	1.0	null
GTEX-RWSA-2426-SM-47JXR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.62373
BRD-K42855618	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23575
Perturb_1278_KO_Ptpn2_SRP108032	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.678
GTEX-V1D1-0008-SM-4JBIJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12154
GTEX-WYVS-2126-SM-3NMA3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878805
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
X-linked severe congenital neutropenia	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.047
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	1.0	2.32014
GTEX-S341-1726-SM-3K2AK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.982261
GTEX-XUW1-0426-SM-4BOOT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.972685
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE240439_1_v_2_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A5-01A-11R-A22L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mammillary part of PHyB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13391
SP in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.85656
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75289
WHSC1	Pathway Commons Protein-Protein Interactions	1.0	null
dorsal nucleus of the lateral lemniscus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91408
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.4328
Perturb_15375_KO|KD_Tip5|Pten_SRP199649	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.02244
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTBP2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231641_0_v_1_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
YD-49-HM53_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.844845
EC-98-KI28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.359736
BL1737 (CARM1)	NURSA Protein Complexes	1.0	null
H3K4me3_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K86986621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.65647
dorsolateral prefrontal cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64445
GTEX-XLM4-1526-SM-4AT6D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72599
BRD-K88504000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47502
substantia nigra reticulata, isthmic part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.9702
BRD-K94346447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2612
FOXP1-21924763-HESCS-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
Perturb_6871_KD_HHEX_SRP323378	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.04688
GTEX-OHPM-0326-SM-33HCA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07504
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PRRC2C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03657
anterior (rostral) cingulate (medial prefrontal) cortex_4 mos_M_12296	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.80411
RPL19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07444
BRD-K08433493	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05607
BRD-K80897487	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42032
superior occipital gyrus, right, inferior bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.75231
primary visual cortex (striate cortex, area V1/17)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.905882
BL2995 (CRTC2)	NURSA Protein Complexes	1.0	null
SRF_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4821-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
LA-42-ER00_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.219296
lymphoid tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.064042
U87MG	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45268
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WY7C-2526-SM-3NB2N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.879358
SC-50 (RB1)	NURSA Protein Complexes	1.0	null
ELF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
ZBTB33_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KALS1	Achilles Cell Line Gene Essentiality Profiles	1.0	1.09803
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K02637547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70623
BACH1	ENCODE Transcription Factor Targets	1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30774
hippocampus (hippocampal formation)_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.11152
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.43131
Perturb_13330_KD_Nfat5_SRP149831	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.43288
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POU2F2_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_4259_KD|OE_HOXB13|MEIS1_SRP201342	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.53451
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.45652
NCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SGCB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.31905
GSE102486,GSE102490_1_v_5_setdb1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CRCGN011_HEPG2_24H:M15	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.18985
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9174882-EMMM-14-e15816-s004.xlsx-MYC_GeneSigs-SCHUHMACHER_MYC_TARGETS_UP_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K15523383	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00827
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.38208
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
golgi apparatus	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-NL3H-0011-R4a-SM-2I3GK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0715
MAX_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5988-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
CRCGN015_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.64493
ZFP69	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11791
smoothmuscle_8b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.01116
UF-27-HS98_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.691987
Liver Neoplasms, Experimental	CTD Gene-Disease Associations	1.0	1.22371
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
UM-UC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.894723
intermediate stratum of Ist	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91149
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-ED-A7PZ-01A-11R-A33R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
seed	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.375368
ATF2_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.5328
diprophylline-1689	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
JURKAT	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GATA1_G1E-ER4_mm9_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
esophagus	HPA Tissue Protein Expression Profiles	1.0	1.04464
BRD-K01463939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01817
clozapine-1289	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_2232_KO_Rela_ERP122918	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.15824
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K98723391	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29979
medial mammillary nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.960965
GSE148066,GSE157787_0_v_4_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_2029_KO_Chd4_SRP173193	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.5885
PMC11225427-13058_2024_1861_MOESM2_ESM.xlsx-Supplemental_Table_S4-Supp_Table_S4_AR_mediated_PGx-eQTL_genes_and_associated_with_all_GWAS_traits_from_GWAS_catalog_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_3715_KD_PIWIL1_SRP188921	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.40739
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AC-84-QG99_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.932479
SN12C	COSMIC Cell Line Gene Mutation Profiles	1.0	null
PRC2_EDD_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	1.0	null
SW837	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.15216
GSE233548_3_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.28114
GTEX-S7PM-0126-SM-4AD6S	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14245
EP300_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EP300_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBC562 (BAT3)	NURSA Protein Complexes	1.0	null
aminophenazone-2060	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
0297417-0002B-6895	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
BRD-K19710723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05637
terbutaline-1585	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE149075_8_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H650	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18227
OC-314	COSMIC Cell Line Gene Mutation Profiles	1.0	null
DND-41	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K22173206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02983
hippocampus (hippocampal formation)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.12983
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SRF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nuclear lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
H3K4me1_G1E-ER4_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BC-25-VR48_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.468466
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.51177
ESRRB-18555785-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
HPAC	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.30216
EGR1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
testis_7b	HPA Tissue Sample Gene Expression Profiles	1.0	1.0903
BL1734 (TBL1XR1)	NURSA Protein Complexes	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XGQ4-2026-SM-4AT6G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.90082
PC-3_[JPC-3]	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BL3114 (PPP4R1)	NURSA Protein Complexes	1.0	null
Retrochiasmatic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.01658
membrane-enclosed lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
Prostate adenocarcinoma_PRAD_TCGA-J4-A67N-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BC-10-SB73_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.32973
PMC11754605-41467_2025_56327_MOESM3_ESM.xlsx-R157K_vs_MSX1-Gene_name_MSX1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K57833824	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.47586
AB-33-EM56_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.674768
EMP2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00489
CB-31-UO16_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.28654
aminocaproic acid-7258	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Box C/D RNP complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.258
JcPL part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.50945
Anterior hypothalamic nucleus, anterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45074
carbachol-5342	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
sirolimus_mus musculus_gpl1261_gse5332	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B0-4839-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2126	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
SNU-475	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.827774
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Penis_Foreskin_Fibroblast_Primary_Cells_skin02	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.897564
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_11165_KO_miR122_SRP135654	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	4.03415
Arcuate hypothalamic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.29917
Perturb_15670_KD_Sf3a1_SRP043160	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.96247
ABL1_knockdown_100_GSE27869	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.60998
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50689779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15228
IC-28-HS37_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.03911
connective tissue	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.052341
ANKS1A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.14911
CSNK2B	MSigDB Cancer Gene Co-expression Modules	1.0	null
Sensory system disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	0.859
BRD-K46913557	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02414
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0011-R9A-SM-4GICI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1236
terminal paraventricular area of THyA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34062
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_13589_KD_Rbm39_SRP360787	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.63437
gland	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.050466
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974159
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleolus	GO Cellular Component Annotations 2015	1.0	null
BL938 (SP1)	NURSA Protein Complexes	1.0	null
HINFP	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.9142
GTEX-SJXC-0526-SM-2XCFG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.91367
ventrolateral prefrontal cortex_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.859564
BL1936 (SMG5)	NURSA Protein Complexes	1.0	null
ATF3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R8A-SM-32PKE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03426
CRCGN017_MCF10A.WT.HP_24H:P13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	1.0	2.21845
6801_PRPF4_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.529117
POLR2A_spleen_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of JcPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.44211
pallidal islands of Calleja	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.46937
BL475 (AHCTF1)	NURSA Protein Complexes	1.0	null
PMC12271601-mmc2.xlsx-OUT_cells_02-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of r10Ve	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.28428
MYOG_myocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Median preoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04645
nucleus of the stria terminalis, medial division, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63165
LA-42-ER00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.55824
WD40 repeat	InterPro Predicted Protein Domain Annotations	1.0	null
Pwp2p-containing subcomplex of 90S preribosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	3.211
PMC11103890-mmc3.xlsx-ZZZ3_interactors_ESC-1-Gene_names_ZZZ3	Rummagene Transcription Factor Associations 2026	1.0	null
UTP18	Pathway Commons Protein-Protein Interactions	1.0	null
496100651_FWM_probable Alzheimer's disease_TBI_83_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.2838
PMC11976845-pr4c00864_si_003.xlsx-Data_S2E_HeLa_LF-Unnamed_4_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K51608472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33754
HDAC2	ENCODE Transcription Factor Targets	1.0	null
BRD-K78748401	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31994
GTEX-QVUS-0011-R4A-SM-3GAE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862027
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN016_MCF10A.WT.HP_24H:P24	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.4963
CBC182 (BICD2)	NURSA Protein Complexes	1.0	null
ChIP_MYC_18555785	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
FE-10-KQ78_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.44375
CAF-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.019
EGR1-20690147-ERYTHROLEUKEMIA-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE146612_2_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-86-7955-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleolus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	2.117
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
seedling	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.359664
Lung adenocarcinoma_LUAD_TCGA-49-4507-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE112762,GSE112767_2_v_3_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Subparaventricular zone	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.018
GTEX-O5YU-0008-SM-4E3I7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.824569
CREB1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBC184 (BICD2)	NURSA Protein Complexes	1.0	null
BRD-A25184723	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.9541
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42648
endonucleolytic cleavage in 5'-ETS of tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)	GO Biological Process Annotations 2023	1.0	null
GSE114992,GSE114993_7_v_10_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE228413_2_v_1_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE121824,GSE121826_0_v_6_scaf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K99000702	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68623
periventricular stratum of m1AD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06459
AP1G2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04999
cellular aromatic compound metabolic process	GO Biological Process Annotations 2015	1.0	null
GSE155695,GSE155696_1_v_0_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE145628,GSE145629_1_v_0_myrf_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K00411149	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15421
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0011-R8A-SM-3MJFC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.883341
BRD-K56034970	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17831
GSE116810_2_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BL2794 (TRIM24)	NURSA Protein Complexes	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6436-01A-11R-1686-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE205976,GSE205978_1_v_0_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
Fetal Death	CTD Gene-Disease Associations	1.0	1.0608
PMC11839389-PUL2-15-e70058-s003.xlsx-FLF_TBX4_mergeRNAseqChIPseq-symbol_TBX4	Rummagene Transcription Factor Associations 2026	1.0	null
amodiaquine-6224	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PU.1-20513432-BCELLS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K19139070	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24251
BC-13-OQ01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.226958
TAF1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K50400833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04609
GSE162276_2_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K88357881	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18263
Acidocalcisome membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.22
lingual gyrus, right, striate	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.859779
intracellular part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.053386
CBC421 (C14orf43)	NURSA Protein Complexes	1.0	null
BRD-K13646706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52706
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.39174
ribosome biogenesis	GO Biological Process Annotations 2025	1.0	null
BFTC-905	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.98805
FOS_MCF 10A_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL3434 (CRTC1)	NURSA Protein Complexes	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.28369
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 320DM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.026
PK-8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28836
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.15745
BRD-K10528627	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06333
BRD-K70532227	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34892
intermediate stratum of OB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07485
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K11874023	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28599
CRCGN017_MCF10A.WT.HP_24H:N21	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.29555
GB1	CCLE Cell Line Gene Expression Profiles	1.0	2.16592
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
reproductive system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GSE124410_3_v_5_stk40_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A23K-01A-11R-A16R-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K05261060	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.12048
nuclear part	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
primary auditory cortex (core)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.42883
H3K4me1_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
DC-51-WE27_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.28727
dorsal entopeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08468
MOLM16	CCLE Cell Line Gene CNV Profiles	-1.0	-1.40523
medial pretectal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04374
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_15374_KD_Pten_SRP199649	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	14.3893
GTEx Stomach 20-29 vs 60-69	GTEx Tissue-Specific Aging Signatures	-1.0	-4.75448
C32	CCLE Cell Line Gene Expression Profiles	-1.0	-1.81154
Dermatome	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.87
PMC4909989-ncomms11840-s2.xlsx-up-regulate-The_YAP_TEAD4-FL_YAP_TEAD4-S_and_YAP_RBM4_regulated_genes_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K95900761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21088
PTMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26469
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A47428621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.17372
H3K4me3_CH12.LX_mm9_4	ENCODE Histone Modification Site Profiles	1.0	null
NCIH1793_LUNG	CCLE Cell Line Proteomics	1.0	2.11068
CACNB4	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K04531886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05528
ETK-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE119978,GSE180930_2_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.15073
JAK1	Kinase Library Tyrosine Kinome Atlas	1.0	96.34
H3K27ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BA-15-LA22_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.300016
GTEX-WFON-0001-SM-3P61W	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39546
nuclear part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.074856
GSE186287_1_v_3_ufm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
imipramine-1685	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CRCGN017_MCF10A.TP53.M_24H:G14	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.15957
GSE125782_3_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K04883778	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.44017
BL2569 (C17orf71)	NURSA Protein Complexes	1.0	null
vitamin c_homo sapiens_gpl570_gds3635	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC3738137-bjc2013359x6.pdf-4-TRPS1_TRPS1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-RVPU-0011-R9A-SM-3NM8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52284
GTEX-NL4W-0011-R4a-SM-2I5GZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.26339
BL2533 (OBFC1)	NURSA Protein Complexes	1.0	null
CRCGN008_HEPG2_24H:O02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.12698
SP1	ENCODE Transcription Factor Targets	1.0	null
EBF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gallbladder_5c	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.870106
internal male genital organ	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
HCC-366	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Nfe2l2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	22.3251
ELK1_01_162	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	1.0	9.79664
GSE213153_1_v_0_ulixertinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE230174_0_v_1_dagla_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-N7MS-0126-SM-3TW8O	GTEx Tissue Sample Gene Expression Profiles	1.0	2.84704
AD-51-SS86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.507657
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.07582
meteneprost-7552	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A549_Belinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0111547
CREM	ChEA Transcription Factor Targets	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-4146-01B-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	-1.0	null
racecadotril-6231	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE149264,GSE149267_4_v_1_trp53_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T8EM-1026-SM-3DB7M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.835751
EPI-2046-1 (CTNNA2)	NURSA Protein Complexes	1.0	null
fusiform gyrus, right, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.07602
GSE235066_7_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
624 MEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.859419
GSE214823,GSE214824_6_v_7_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.5204
FD-20-OG99_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.351404
NANOG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00469275
SW48	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.4229
EF-80-OD07_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.309735
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0126-SM-4B66N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.97933
HCC3153	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.09834
Perturb_9560_KO_Marchf3_SRP278315	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.2943
RERF-LC-KJ	COSMIC Cell Line Gene Mutation Profiles	1.0	null
intracellular non-membrane-bounded organelle	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GTEX-WHSE-0011-R3A-SM-3P5ZM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911078
YKG1	CCLE Cell Line Gene Expression Profiles	-1.0	-1.72703
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
RCOR1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
adenosine phosphate-1622	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_14019_OE_Nras_SRP332459	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.53671
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular organelle lumen	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
GATA1_G1E-ER4_mm9_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ7-0011-R5a-SM-33HBK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30355
nuclear lumen	GO Cellular Component Annotations 2025	1.0	null
PMC12695649-41588_2025_2389_MOESM2_ESM.xlsx-GATA6_RIME-_AsPC-1-Gene_Symbol_GATA6	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K12749985	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34434
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.86351
NCOR1	ENCODE Transcription Factor Targets	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KA-81-AG66_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.42317
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RELA_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO-818	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.922575
rhombomere 11	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	3.64402
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831439
BL7432 (ZNF326)	NURSA Protein Complexes	1.0	null
BL4287 (PPP2R5A)	NURSA Protein Complexes	1.0	null
SIN3A_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
URM1	Pathway Commons Protein-Protein Interactions	1.0	null
FOXM1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Ca9-22	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.25605
Kidney renal papillary cell carcinoma_KIRP_TCGA-MH-A854-01A-11R-A355-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH-6	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.31245
CRCGN012_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14892
outer SZ in frontal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.899386
cellular_component	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.603
suprachiasmatic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69487
EP300_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
SIN3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CBC191 (ERCC6L)	NURSA Protein Complexes	1.0	null
BL8105 (AHDC1)	NURSA Protein Complexes	1.0	null
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
poly(a) rna binding	GO Molecular Function Annotations 2015	1.0	null
CRCGN017_MCF10A.WT.HP_24H:P05	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.46855
Perturb_14248_KD_HNRNPC_SRP353785	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	5.48058
JUND	ENCODE Transcription Factor Targets	1.0	null
SC-8002 (ESR1)	NURSA Protein Complexes	1.0	null
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.091
HCC70	CCLE Cell Line Gene CNV Profiles	1.0	1.35798
BL9240 (GREB1)	NURSA Protein Complexes	1.0	null
GSE114883_0_v_5_romidepsin_human	RummaGEO Drug Perturbation Signatures	1.0	null
disease	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.039495
GSE240439_1_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-RU72-0011-R2A-SM-2TF6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.9127
Prostate adenocarcinoma_PRAD_TCGA-EJ-A65D-01A-11R-A30B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Respiratory system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
VDR-23849224-CD4+-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
Perturb_6759_KO|KD_IER5_SRP103746	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-11.2089
Perturb_3904_KD_HNF4A_SRP123224	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.68189
t-utp complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	1.35266
TAL1_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1975	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.3094
WD40-repeat-containing domain	InterPro Predicted Protein Domain Annotations	1.0	null
protein binding	GO Molecular Function Annotations 2015	1.0	null
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
intracellular part	GO Cellular Component Annotations 2015	1.0	null
intracellular part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
Perturb_4258_KD_HOXB13_SRP201342	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.65008
BL2758 (MED17)	NURSA Protein Complexes	1.0	null
JADE3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.35458
HCC70	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.560687
SOWAHC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.37797
outer CP in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02596
SRF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17620_KO_MLLT6_SRP245883	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.1572
GSE152734,GSE152735_2_v_0_pbrm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE137177_2_v_0_folic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BL2747 (C1D)	NURSA Protein Complexes	1.0	null
GSE221327_4_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	1.0	null
mantle zone of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33874
CCAR2_02_86	KnockTF Gene Expression Profiles with Transcription Factor Perturbations	-1.0	-0.63652
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934718
rRNA modification in the nucleus and cytosol	Reactome Pathways 2024	1.0	null
ab92734 (PJA2)	NURSA Protein Complexes	1.0	null
AD-51-FB60_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.886948
KDM5B_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL6636 (FOXK2)	NURSA Protein Complexes	1.0	null
BL3893 (RAD9A)	NURSA Protein Complexes	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
AXL	Kinase Library Tyrosine Kinome Atlas	1.0	98.01
SIX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53067
nocodazole-7145	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HCC1569	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.693561
nuclear part	GO Cellular Component Annotations 2015	1.0	null
GSE63048_11_v_6_morc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BL2457 (UBE2L3)	NURSA Protein Complexes	1.0	null
vestibular nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.994991
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.851319
GABPA_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K45394633	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.9894
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CRCGN014_HEPG2_24H:K23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.14527
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Familial temporal lobe epilepsy 4	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.778
Perturb_11339_KD_Mll4_SRP241682	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.0088
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18868
GTEX-OHPL-0326-SM-33HC8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03912
nucleobase-containing compound metabolic process	GO Biological Process Annotations 2015	1.0	null
BC-00-YH62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.612607
LS1034	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.14819
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.84697
Perturb_12034_KO_Eed_SRP075353	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.376
BL4386 (MAGED2)	NURSA Protein Complexes	1.0	null
trunk	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
BRD-U28903152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2573
AC-45-YY00_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.252185
GTEX-QDT8-0011-R6A-SM-32PKI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01983
MYC_Activation - 4 hours_GDS2025_724_mouse_Pancreatic islet beta cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.60548
GSE120612_6_v_1_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
15520171-Table1	GeneSigDB Published Gene Signatures	1.0	null
Perturb_6504_KD_PIEZO1_SRP140640	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	3.38421
Amastigote	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.752
BRD-K17850764	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17201
JUN-27471255-CHONDROCYTES-MOUSE-RIB	ChEA Transcription Factor Targets 2022	1.0	null
r1 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.57495
inner SZ in inferolateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.920315
A431	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.79921
GSE196505,GSE196507_1_v_2_kdm2b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MDA-MB-157	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.913531
ASPC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.953553
Cervical carcinoma cell	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
superficial stratum of r11Tr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.4155
Fields of Forel	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32553
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB33_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HPAC	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.895805
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
GTEX-U8XE-0526-SM-3DB8R	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01612
GSE57875_1_v_0_hnrnpl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Perturb_8851_KD_MLKL_SRP165226	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.89783
CREB1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUP58	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.07763
GATA1_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
preopto-hypothalamic area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0178
rostral interpeduncular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13286
GTEX-OHPL-0126-SM-2HMJ7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1211
GSE147662_3_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TAL1-20566737-PRIMARY-FETAL-LIVER-ERYTHROID-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-PSDG-0008-SM-48TE5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13421
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862497
H3K4me1_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5881-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
nucleolus	GO Cellular Component Annotations 2025	1.0	null
E2F4-21247883-LYMPHOBLASTOID-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE255680_2_v_0_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WWYW-0011-R8A-SM-3NB3S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.05853
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.868404
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_15605_KO_Esrp1/Esrp2_SRP051370	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.35485
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.14339
GSE149075_1_v_4_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8120022-CTM2-11-e420-s006.xlsx-Sheet1-Table_S1_786_altered_genes_involved_in_cancer-related_pathway_in_TMPRSS2_ERG_fusion-positive_prostate_cancer_Genes_involed_in_multiple_pathways_are_duplicated_ERG	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10807933-NIHMS1954791-supplement-4.xlsx-Bag6_KD_proteomics-Unnamed_5_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Rectum adenocarcinoma_READ_TCGA-DC-6155-01A-11R-1660-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AB-04-NN16_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.200705
DD-36-YH76_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.713799
HEY2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.8108
GSE179531_1_v_0_metformin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-MF-A522-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H2198	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869499
H3K79me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TBP	ENCODE Transcription Factor Targets	1.0	null
FOSL1-28411283-MDA231-LM2-4175-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K30283890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42617
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MXI1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CF-42-OS28_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.251333
FANCI	Pathway Commons Protein-Protein Interactions	1.0	null
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0011-R9A-SM-4AT45	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29334
MYC_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CFAP68	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.57331
paraventricular nuclei, left of thalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.824262
CAOV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.70735
BL2882 (CHEK2)	NURSA Protein Complexes	1.0	null
PMC12271601-mmc2.xlsx-OUT_cells_01-Gene_Symbol_TCF23	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131660_2_v_0_piperlongumine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Male pronucleus	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.848
Perturb_8849_KD_MLKL_SRP165226	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.12762
Perturb_17359_OE_CREB_SRP334442	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.77546
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A194-01A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LDB1-21186366-BM-HSCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
KASUMI-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.32366
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-ETV4_ETV4	Rummagene Transcription Factor Associations 2026	1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
occipital neocortex_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.865109
membrane-enclosed lumen	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
GSE179880_2_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BL2441 (RNF4)	NURSA Protein Complexes	1.0	null
AB-21-VE32_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.267252
GTEX-X15G-1626-SM-3NMB3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884321
Brain Lower Grade Glioma_LGG_TCGA-FG-A6J1-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K33461572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27683
E2F4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0805
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE167218_1_v_0_hoxd12_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE114992,GSE114993_7_v_3_irf5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CBC411 (AHCTF1)	NURSA Protein Complexes	1.0	null
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21763
Monogenic disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.039
r1 part of basomedial reticular formation	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03306
BRD-K02781189	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26158
A549_Ramelteon_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.013163
E2F1-18555785-MESCS-MOUSE	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1-33199912-293T-HUMAN-KIDNEYEMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
NR6A1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	24.7708
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLM-16	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.44733
496100316_TCx_no dementia_TBI_79_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.45412
ETS1_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92364_1_v_5_asparaginase_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K66715657	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14172
orbital frontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.881814
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
uterus	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
small-subunit processome	GO Cellular Component Annotations 2025	1.0	null
liver	HPA Tissue Gene Expression Profiles	-1.0	-0.946238
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0011-R4A-SM-2I5FD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.57066
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
GATA3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12211054-spectrum.00100-25-s0002.pdf-34-TAL1_TAL1	Rummagene Transcription Factor Associations 2026	1.0	null
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03382
Bladder Urothelial Carcinoma_BLCA_TCGA-BT-A42F-01A-11R-A23W-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nuclear matrix	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.332848
Brain Lower Grade Glioma_LGG_TCGA-FG-A6IZ-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Catalytic step 2 spliceosome	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.342
trifluoperazine-7420	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EPI-2064-1 (ERBB2)	NURSA Protein Complexes	1.0	null
BRD-K49325049	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11129
6863_PSMC6_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.541641
IGR-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FADU	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.01224
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHESOAD1	Achilles Cell Line Gene Essentiality Profiles	-1.0	-1.67686
GTEX-QMR6-0011-R2A-SM-32PKV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.935675
SA-32-CC58_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.69927
bone	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.055362
GSE244072_10_v_8_tfeb_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OOBK-2626-SM-2HMKY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.969876
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.913136
FE-82-WB22_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-2.02838
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFJO-1026-SM-3GIKL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875456
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CBC174 (AGAP3)	NURSA Protein Complexes	1.0	null
BRD-K55742134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6251
Perturb_2829_OE_IGF1R_SRP064353	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.0383
substantia nigra, pars compacta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.53453
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.215224
U-698-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.54723
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896636
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
intracellular	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
PMC12069319-Table1.xlsx-OCAB_p34_BirA-Gene_POU2AF1	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_13238_KO_Flcn_SRP126727	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-4.12306
ETS1-20019798-JURKAT-HUMAN	ChEA Transcription Factor Targets 2022	1.0	null
H3K4me1_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5683-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Heart conduction disease	DISEASES Experimental Gene-Disease Association Evidence Scores 2025	1.0	1.888
craniofacial region	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.119815
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBX2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
IHH-4	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE198165,GSE198166_0_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XYKS-2126-SM-4E3IB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0574
Perturb_3711_KO_PIWIL1_SRP188921	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.01174
KG-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.06961
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SUP-T1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-X8HC-0126-SM-4E3JW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86935
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16329
BRD-K67832115	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.54708
BRD-K99077411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07576
BRD-K94582694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00588
retromammillary area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13207
Nucleolus	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	2.603
outer CP in midlateral extrastriate cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23429
BCL3_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
etofylline-1409	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
rifamycin-sv	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18291
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JX-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Golgi lumen	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.857
amygdaloid complex_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.96317
GTEX-NL4W-0011-R2a-SM-2I5GV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00069
EB-09-OC36_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.228687
BL406 (RFC3)	NURSA Protein Complexes	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mediodorsal nucleus of thalamus_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.879147
DAOY cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.92
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL1103 (CENPB)	NURSA Protein Complexes	1.0	null
posteroventral (inferior) parietal cortex_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.855865
EIF3I	MSigDB Cancer Gene Co-expression Modules	1.0	null
BRD-K03467766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21632
primary somatosensory cortex (area S1, areas 3,1,2)_30 yrs_F_12290	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.08864
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RELA_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE246335_4_v_5_tp53_human	RummaGEO Gene Perturbation Signatures	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
AA-88-PJ86_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.32589
GTEX-XQ3S-1426-SM-4BOPR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03398
GTEX-PX3G-1626-SM-2S1PT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29041
imatinib_homo sapiens_gpl96_gds3042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
HMY-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.72938
REST_PFSK-1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229973_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
organelle part	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
BL2290 (BTBD12)	NURSA Protein Complexes	1.0	null
NCI-H2595	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.958536
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.88287
preribosome	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.03318
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prestwick-559-1728	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
3050_FDPS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.510832
GTEX-RVPV-0008-SM-47JYW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.908964
BRD-K76618080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.46882
Perturb_4811_KO_Mapk1_ERP004375	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-1.58723
GTEX-T5JC-0011-R9A-SM-32PLV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17935
EJM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-3.19879
inner CP in primary auditory cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.966108
BRD-K60635455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00636
GTEX-OXRL-2126-SM-3NM98	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88276
AB-00-IL62_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.229766
NCIH1105	CCLE Cell Line Gene Expression Profiles	-1.0	-2.19642
WB-48-EF24_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.901234
BRD-K82842087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80557
GSE212330_1_v_0_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
AML193	Achilles Cell Line Gene Essentiality Profiles	1.0	1.09265
PA-TU-8988S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.869499
raubasine-6360	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Ebf4	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	28.617
MYC_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.05122
BL4839 (WDHD1)	NURSA Protein Complexes	1.0	null
BFTC-905	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.53069
primary motor cortex (area M1, area 4)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.950582
RIOK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.4741
MDAMB361	CCLE Cell Line Gene CNV Profiles	1.0	1.65594
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
cytoplasmic part	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.045112
cellular_component	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.048279
FOXP1-21924763-HESC-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.1783
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-A6EP-01A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_3885_KD_EIF2B5_SRP124930	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-14.4894
substantia innominata/basal nucleus, transitional part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29739
GTEX-XPVG-2226-SM-4B65U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.59708
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08258
GSE202434,GSE202438_9_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ATF3_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE215086_3_v_0_batf_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-56-8083-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE195743_3_v_2_lhx6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QCQG-1326-SM-48U24	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12348
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.847028
BL1683 (BUB1)	NURSA Protein Complexes	1.0	null
Peroxisomal importomer complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.749
diphenhydramine-1871	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Sarcoma_SARC_TCGA-FX-A48G-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K11566857	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.4351
MYC-18358816-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
cell	COMPARTMENTS Experimental Protein Localization Evidence Scores	1.0	1.02676
HCFC1_ES-E14_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FERD3L	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.8888
HS 746T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.93688
POLR2AphosphoS2_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores	1.0	null
BL4935 (TRIM47)	NURSA Protein Complexes	1.0	null
TCF12_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ_CH12.LX_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL1258 (MDM4)	NURSA Protein Complexes	1.0	null
BRD-K11414036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.11248
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Major pathway of rRNA processing in the nucleolus and cytosol	Reactome Pathways 2024	1.0	null
Golgi-associated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.944
496100556_TCx_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.30285
CA-48-SW47_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.660218
inner SZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03416
H3K4me2_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE186223,GSE186224_6_v_3_hmces_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K79264000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63046
Perturb_13271_KO_Msl2_SRP192624	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.07339
hippocampus (hippocampal formation)_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02162
GSE48812_8_v_5_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
USP11	Pathway Commons Protein-Protein Interactions	1.0	null
H3K18ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
NIH:OVCAR-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.07329
SP1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-2026-SM-4E3KA	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08305
mediodorsal nucleus of thalamus_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.923811
trichome	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	1.47335
DNAJB1	Hub Proteins Protein-Protein Interactions	1.0	null
orbital frontal cortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.16018
BRD-A68123879	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43646
GSE110178_1_v_0_tranylcypromine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
REC1	CCLE Cell Line Gene Expression Profiles	1.0	1.41178
gill	TISSUES Text-mining Tissue Protein Expression Evidence Scores	1.0	0.446038
CREB1	JASPAR Predicted Transcription Factor Targets	1.0	null
BRD-K46897949	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55143
REST	ENCODE Transcription Factor Targets	1.0	null
GTEX-QEG5-1426-SM-447AS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03894
CEBPB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL1239 (MAML1)	NURSA Protein Complexes	1.0	null
RCOR1	ENCODE Transcription Factor Targets	1.0	null
JD-44-KF86_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-1.55054
DDX41	Pathway Commons Protein-Protein Interactions	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-P5-A72W-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YD-49-HM53_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.674936
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0726-SM-48FCZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.93301
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IZ in caudal midinferior temporal cortex (area TF)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.856292
NR3C1	ENCODE Transcription Factor Targets	1.0	null
TBXT	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.6428
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HeLa cell	ProteomicsDB Cell Type and Tissue Protein Expression Profiles	1.0	0.986861
GABPA_MEL cell line_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
abdomen	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
lm7	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.556
ivermectin-2051	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K79me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JHH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39471
KE-47-IA01_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.288234
BL1536 (TREX1)	NURSA Protein Complexes	1.0	null
BRD-K21610715	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04101
BL3283 (C7orf27)	NURSA Protein Complexes	1.0	null
BRD-K30782795	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07166
pentetrazol-1408	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-T5JW-0426-SM-4DM7M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.832556
GSE112763,GSE112767_4_v_5_dgcr8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE112860_3_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dorsolateral prefrontal cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.3656
PROM2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52223
BRD-K00973124	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5355
Perturb_3416_KO_Cdx2/Apc_SRP093647	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
BRD-K58277621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25577
Neurod2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	35.819
cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores	1.0	0.044189
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-77-8144-01A-11R-2247-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DD-54-MA35_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.293163
intermediate stratum of TPaA	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14086
BL1002 (ATF7IP)	NURSA Protein Complexes	1.0	null
HSC-39	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SIN3A_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_G1E-ER4_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE231745_1_v_0_venetoclax_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K47349225	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2981
intracellular organelle	COMPARTMENTS Text-mining Protein Localization Evidence Scores	1.0	0.041854
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58436
EGR4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.18169
BRD-K20737562	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23334
Drug-Induced Liver Injury	CTD Gene-Disease Associations	1.0	1.84055
GTEX-WH7G-1926-SM-4LVMM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.02301
GTEX-P4PQ-0126-SM-2S1NM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08963
BRD-K45569026	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69134
SPI1	ENCODE Transcription Factor Targets	1.0	null
FXR	MotifMap Predicted Transcription Factor Targets	1.0	null
AB-85-JR73_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.252895
Perturb_8479_KD_CSDE1_SRP117243	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.30883
BRD-K56916066	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03398
GSE197630_1_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DH-A669-02A-11R-A31N-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
rectum_8a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.10722
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ZBTB33_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BL132 (MSH6)	NURSA Protein Complexes	1.0	null
GSE163862_2_v_3_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
CRCGN011_HEPG2_24H:O01	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.302
Perturb_205_KD_Robo1/Id1/ld3_SRP193147	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.0908
Sarcoma_SARC_TCGA-IW-A3M5-01A-22R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CAL-33	GDSC Cell Line Gene Expression Profiles	1.0	1.44206
H2373	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K32485819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1409
H3K79me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Inflorescence meristem	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.96
Follicular thyroid cancer cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.518
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.45376
KF-18-RY71_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.636589
pwp2p-containing subcomplex of 90s preribosome	GO Cellular Component Annotations 2015	1.0	null
nucleus	COMPARTMENTS Curated Protein Localization Evidence Scores	1.0	0.237908
HDAC3	Pathway Commons Protein-Protein Interactions	1.0	null
CB-16-SY72_0.1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	-1.0	-0.580674
PC-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14954
Kidney renal clear cell carcinoma_KIRC_TCGA-AK-3447-01A-01R-1766-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null