association	dataset	threshold value	standardized value
H3K4me3_Penis Foreskin Keratinocyte Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K75985122	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36714
GSE184902_4_v_1_adipor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
DOCK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00661086
GSE232558_0_v_1_fbxl12_human	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of ion transmembrane transporter activity	GO Biological Process Annotations 2015	1.0	null
GSE116810_5_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
SOBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0058963
RAD21_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0005-SM-3GIKM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.28096
HL-60	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.23141
Kidney renal papillary cell carcinoma_KIRP_TCGA-GL-6846-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of pedal digit skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-655	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
PMC9377669-tx1c00392_si_002.xlsx-Chlorophenamine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
superficial stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13671
GTEX-XQ8I-1926-SM-4BOOK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.879395
CRCGN008_HEPG2_24H:K02	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-5.07912
Acute Myeloid Leukemia_LAML_TCGA-AB-3008-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78009480	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06465
H3K4me3_Panc1_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_3_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
haloperidol-2704	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOSL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sarcoma_SARC_TCGA-DX-A1KY-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3973	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
H3K27ac_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE116810_5_v_3_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Corpus callosum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.29
Kidney renal papillary cell carcinoma_KIRP_TCGA-B9-7268-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K48012250	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05818
PMC11976845-pr4c00864_si_003.xlsx-Data_S2E_HeLa_LF-Unnamed_4_LTF	Rummagene Transcription Factor Associations 2026	1.0	null
PML_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-A3-3385-01A-02R-1420-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BLOC1S6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00510476
placenta_3a	HPA Tissue Sample Gene Expression Profiles	1.0	1.71913
GTEX-T6MN-0011-R10A-SM-32QP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21936
EWSR1-FLI1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	119.876
BRD-K45271289	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47525
CTCF_fibroblast of gingiva_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226249_2_v_7_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE130396_1_v_6_neratinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ELK1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-N7MT-0011-R6a-SM-2I3G3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.87219
GTEX-WEY5-0006-SM-3GIKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63651
phenotypic abnormality	GWASdb SNP-Phenotype Associations	1.0	0.496606
POLR2A	ENCODE Transcription Factor Targets	1.0	null
GSE242049_1_v_0_txndc5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NFIC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_G007-LK_10然_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0168943
ferulic-acid	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00636
GSE226249_5_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
IRAK2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE164874_5_v_7_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FHIP1A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00472992
CTCF_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RXRA	ENCODE Transcription Factor Targets	1.0	null
CTCF_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of THyB-P	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17729
r7 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.61
striatal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34102
mantle zone of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03607
GTEX-X638-0005-SM-47JX6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09693
negative regulation of cell migration	GO Biological Process Annotations 2025	1.0	null
GTEX-R55E-0011-R5A-SM-2TC5N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14254
adrenal_4d	HPA Tissue Sample Gene Expression Profiles	1.0	1.07501
BRD-A35588707_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE211177,GSE211178_9_v_11_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A47342814_naltrindole_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
A549_G007-LK_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141897
GSE66931,GSE73382_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PML_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MSX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8878
GSE220058,GSE220059_0_v_1_prrc2b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE160373_1_v_7_pparg_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.97643
OVSAHO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898209
CTCF_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPK-0006-SM-2HMKH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.01579
LDHA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00310325
Lung squamous cell carcinoma_LUSC_TCGA-77-8007-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pineal_night	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.19269
BRD-A52650764_Ingenol 3, 20-dibenzoate_RKO_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cSARS Bat SRBD_12Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.46988
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OE-01A-11R-A206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
JUND_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193993_1_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE148692,GSE148695_7_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE116810_5_v_1_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K83127279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.00989
GSE158834_2_v_5_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mediodorsal nucleus of thalamus_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.50116
GSE210655_3_v_4_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
body of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22216
BRD-K63500288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05796
BRD-K05562558_-666_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_kidney_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-374c	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
CTCF_kidney epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8903_TIAL1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.90464
periventricular stratum of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20753
ELF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE242333_0_v_1_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Tripartite attachment complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.047
GTEX-WOFL-0006-SM-3TW8K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.4152
GSE164529_0_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SUM149PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.61407
18440302-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
Pod	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.525
SG in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.997882
NCIH1355_LUNG	CCLE Cell Line Proteomics	1.0	2.63874
GSE155852_0_v_2_apigenin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_WI38_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE255432_4_v_3_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6835-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-RTLS-0006-SM-2TF58	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01058
BRD-K11859767	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47446
BDCA4+_DentriticCells	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.27064
CTCF_fibroblast of skin of abdomen_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.80888
KNS60	DepMap CRISPR Gene Dependency	1.0	2.45703
Claustrum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15349
H3K4me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
orbital frontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.75198
levodopa-1892	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TGIF1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.8978
JHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	3.24385
CTCF	ENCODE Transcription Factor Targets	1.0	null
A549_S-Ruxolitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163552
TCF3	ChEA Transcription Factor Targets	1.0	null
RUNX1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.21062
Prostate adenocarcinoma_PRAD_TCGA-YJ-A8SW-01A-11R-A37L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CAPAN1	DepMap CRISPR Gene Dependency	1.0	2.30955
Paramedian lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.27626
lower limb region of M1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.94437
BRD-A03121430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.35592
GTEX-OXRO-0011-R2A-SM-3NB1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.859908
DMS 273	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01446
hsa-miR-1279	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
RAD21_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_13981_KD_Elavl2/Elavl3/Elavl4_ERP133202	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.97149
GSE158834_7_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Tucidinostat_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0120376
GSE157555,GSE157556_3_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.826405
GSE181003_1_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
CDC42SE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12617
BRD-K02866760	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40179
ELF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE188870,GSE188871_0_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NCIN87	CCLE Cell Line Gene CNV Profiles	-1.0	-1.33657
GSE258991_5_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE222047_0_v_1_imidazole_human	RummaGEO Drug Perturbation Signatures	1.0	null
trpm8	GeneRIF Biological Term Annotations	1.0	null
GTEX-R55F-0011-R8A-SM-2TF4F	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42599
POLR2A_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IM-95	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95802
BRD-K98810653	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25132
primary motor cortex (area M1, area 4)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.47356
NT2/D1 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.991
karpas707	HPA Cell Line Gene Expression Profiles	-1.0	-0.848579
GTEX-WWYW-0011-R7A-SM-3NB3H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.92883
hsa-miR-655	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
PMC5263239-mmc2.xls-SEM_siMLL-AF4-MLL-AF4_gene_targets_with_decrease_in_MLL-AF4_ChIP-seq_signal_2198_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
CREB1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PSMG1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00601452
H3K27ac_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE129293_0_v_1_chd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125782_0_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_Brain Inferior Temporal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE233679_5_v_3_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE115395_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
mRNA_TCF3_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K02959126	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77491
protein binding	GO Molecular Function Annotations 2015	1.0	null
KMS11	DepMap CRISPR Gene Dependency	1.0	2.69312
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-GR-A4D4-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary motor cortex (area M1, area 4)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2121
cellular_component	GO Cellular Component Annotations 2015	1.0	null
GTEX-X585-0011-R6A-SM-46MVJ	GTEx Tissue Sample Gene Expression Profiles	1.0	2.4016
GSE151090_2_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-582-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE208634_1_v_0_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
captopril-4585	CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RAD21_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hemispheric regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43248
COR-L88	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.07166
EMX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1505
GTEX-VJYA-0526-SM-4KL1R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.850321
prostate_4c	HPA Tissue Sample Gene Expression Profiles	1.0	0.880265
SNU61	DepMap CRISPR Gene Dependency	1.0	4.60818
Whole body	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
Lymph node carcinoma	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.396
GTEX-T5JC-2426-SM-3NMDB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.936485
GSE216273,GSE216292_0_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
FOXA1	ENCODE Transcription Factor Targets	1.0	null
imipramine-1807	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
eGFP-HDAC8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.3756
PMC4944136-srep28995-s2.xls-OTX2-gene_OTX2	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K30462643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.42227
GSE111385_2_v_3_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
TLK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00380905
dizocilpine-1386	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.46986
GSE171180,GSE171181_0_v_1_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-HM-A6W2-06A-22R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23533429	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20145
6446_PLEKHJ1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.581966
H3K4me3_astrocyte of the cerebellum_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
brain	HPA Tissue Gene Expression Profiles	1.0	0.844609
GSE152432_9_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A3CE-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.45012
GSE158834_2_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P78B-0005-SM-2I5GM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11382
hsa-miR-4437	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
BRD-K72073851	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56274
GSE105169,GSE105175_0_v_1_dhx36_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE144231_2_v_7_cxcr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE249098_3_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SP1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12873_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
3-hydroxy-DL-kynurenine-1109	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Skin	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
hsa-miR-3675-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
cerebellar white matter	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20674
VZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19847
POLR3H	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00943097
HDAC1	ENCODE Transcription Factor Targets	1.0	null
striatum_13 yrs_F_12831	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.13427
GSE182179_2_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE89018_12_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-SSA3-0005-SM-32QOT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17042
ELF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A67788537_Salermide_A375_24.0_h_120.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
IRF2	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE205788_0_v_1_gfap_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A78360835_cercosporin_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE135030_3_v_10_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QVUS-0011-R3A-SM-3GAFD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.37655
BRD-K16954129	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47378
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.69523
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7654-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
pontobulbar body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55614
GSE157555,GSE157556_0_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE95302_2_v_3_tamoxifen_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WZTO-3026-SM-3NMA2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10515
18818702-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
dorsolateral prefrontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.01719
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-6950-01A-11R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE88819_5_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Diverticulitis	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.028
19286929-SuppTable2q	GeneSigDB Published Gene Signatures	1.0	null
GSE205976,GSE205978_2_v_4_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
LY-294002-1007	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K06180729_DM163 BRD-K06180729_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RBBP5	ENCODE Transcription Factor Targets	1.0	null
A549_Divalproex Sodium_100nM_72h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139159
PMC8709578-elife-69843-supp2.xlsx-HSF1_KO_2_E2_30min-Nearest_Ensembl_HSF1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
CHD1	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4766-5p	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
ivermectin-1367	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LMX1A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.5672
binding	GO Molecular Function Annotations 2015	1.0	null
MAX_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE140607_3_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-3170	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
GTEX-QVJO-0011-R4A-SM-2S1QL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.98089
BRD-K56024445	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52548
Crus 2, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.5156
SIRT6_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K49704392	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10576
NCI-H2052	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983913
hsa-miR-548c-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.389112
outer portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.14683
H3K4me1_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
K562_Busulfan_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153136
H4K20me1_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTF2F1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7284-01B-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WL46-0011-R2A-SM-3LK6O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.48648
CHAGO-K-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15063
GSE178907_0_v_3_fkrp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XUZC-0226-SM-4BOO7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49321
Prostate Carcinoma	DisGeNET Gene-Disease Associations	1.0	null
bretylium tosilate-3057	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WWYW-0011-R5A-SM-3NB3E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.26373
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-SOX4_SOX4	Rummagene Transcription Factor Associations 2026	1.0	null
RCOR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SOX2_Deficiency_GDS4853_320_human_AZ-521 gastric cancer (GC) cell line - 12 Hours	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_2_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CTSD	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09697
posterolateral cortical amygdaloid area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08806
CREB1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SERP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01229
CTCF_fibroblast of pedal digit skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
head of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.21853
BRD-K94325918_-666_NCIH596_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE198165,GSE198166_7_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228992_0_v_1_mafb_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T2YK-0005-SM-32QOV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01325
GTEX-S341-0526-SM-4AD5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.849964
GSE146840,GSE146842_3_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Leukemia, Chronic T-Cell_T lymphocyte_GSE5788	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.77785
Crus II, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.5296
positive regulation of transmembrane transport	GO Biological Process Annotations 2015	1.0	null
GSE169697,GSE169725_0_v_5_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.03287
GSE216043_10_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NDUFA10	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-A76490030_K784-3131_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE158431_2_v_3_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K28907958_-666_SW948_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_epithelial cell of esophagus_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.28956
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.21866
ZBTB7A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6928102__F5	PFOCR Pathway Figure Associations 2023	1.0	null
POLR2A_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157262,GSE157268_3_v_0_ythdc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE135514_2_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE94849_3_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-All_targets_genes_names_2597_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NL3H-0011-R6a-SM-2I3G8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.10635
putamen, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.924951
POLR2A_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54364215	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68623
USP19	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00361772
GSE195743_1_v_4_lhx6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE225901_0_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Amisulpride_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149361
BRD-A15010982_10006350_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-WL46-0011-R10A-SM-3MJFQ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27727
CTCF_GM12864_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3BM-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BT12	DepMap CRISPR Gene Dependency	1.0	2.16443
PMC11465086-mmc2.xlsx-Table_ES_1_markers_c0_LPS_Vs_Co-Gene_Expression_Data_1_markers_c0_LPS_Vs_Control_related_to_Figure_5_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
STIP1	Pathway Commons Protein-Protein Interactions	1.0	null
H3K9ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE253041_1_v_0_ramp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
REXO1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.27144
emboliform nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.85132
GSE248858_4_v_2_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UKE-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72253
posterior (caudal) superior temporal cortex (area 22c)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.55184
HOXA9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00607686
YY1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_erythroblast_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
TMEM132A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.039
Perturb_17920_KO_Nhlrc1_SRP328155	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.84463
BRD-K53725468	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0688
BRD-K27141178_SB 203186 hydrochloride_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
primary visual cortex (striate cortex, area V1/17)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.06381
USF2	JASPAR Predicted Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-5514-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
triamcinolone-1395	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RT11284	DepMap CRISPR Gene Dependency	1.0	2.84547
BRD-K83185986	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0013
GSE130081,GSE130082_0_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-HAND1_HAND1	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_GM18951_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18535662-TableS1a	GeneSigDB Published Gene Signatures	1.0	null
CCNH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00395478
GSE231648_4_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE161064,GSE161065_0_v_1_kdm5b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_fibroblast of villous mesenchyme_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE203308_7_v_0_brf1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-6837-11A-01R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Declive (VI)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.69154
BRD-K14166090	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33627
Nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE112860_0_v_8_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE186471_1_v_2_carnosol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A50737080_CGK 733_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MT1M	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00443073
central medullary reticular group, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.837393
CTCF_GM12867_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
skeletal muscle	HPA Tissue Gene Expression Profiles	-1.0	-0.974469
H3K4me3_epithelial cell of esophagus_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
KNS-62	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.981108
H3K4me1_Adult Kidney	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Collagen beaded filament	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.778
positive regulation of anion transport	GO Biological Process Annotations 2015	1.0	null
NFYB_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WRNIP1	ENCODE Transcription Factor Targets	1.0	null
HCRT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00544767
DIPK2A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.34465
FOXO3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.004362
GSE103068_5_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GATA2	ENCODE Transcription Factor Targets	1.0	null
GTEX-X4XX-3026-SM-3NMB2	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96411
GTEX-Q734-0006-SM-2I3FJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0697
IGSF8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00487101
GSE229973_4_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-A10523515_GSK-429286A_MCF7_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FOXO3-23340844-DLD1-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
bcl11b_18199763_brain_lof_mouse_gpl1261_gds3178	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.043862
MCF7_JNJ-26854165_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0118708
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB2-627E_0Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	0.727314
RERFLCSQ1_LUNG	CCLE Cell Line Proteomics	1.0	4.74999
VMRCRCW	CCLE Cell Line Gene CNV Profiles	1.0	1.86987
GSE119978,GSE180930_2_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
striatum_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.48547
GSE92457_7_v_8_ethanol_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Trophoblastic neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.169
pontine nuclei, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.85004
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8XJ-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-FG-8182-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K72787967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.43909
H3K9ac_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6847-01A-11R-1949-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIG-M5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12764
NFIC_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QXCU-0006-SM-2TC5K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.965528
A549_AG-490_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0203078
dentate gyrus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.5673
GSE184902_3_v_0_adipor1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SJRH30	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-4665-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GSE216043_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE138818_1_v_3_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OIZF-0006-SM-2I5GQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17914
hsa-miR-548a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
BRD-K21313369	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00999
GSE217552_3_v_2_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE182680,GSE182683_7_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-4264	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE178255_1_v_7_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K68336408_Tyrphostin AG 1478_VCAP_24.0_h_56.78_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE127790_10_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8435-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE235596_0_v_1_pikfyve_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lung adenocarcinoma_LUAD_TCGA-91-6836-01A-21R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_embryonic fibroblast_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vitamin c_homo sapiens_gpl570_gse11919	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE122215,GSE122217_0_v_1_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_cardiac muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XV7Q-0226-SM-4BRVL	GTEx Tissue Sample Gene Expression Profiles	1.0	0.895503
regulation of anion channel activity	GO Biological Process Annotations 2015	1.0	null
GTEX-WH7G-0008-SM-4LVNM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.993242
KYSE-140	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09057
BRD-K39120595_BITHIONATE SODIUM_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_SK-N-MC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE211128_2_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_7_v_12_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC12500934-41408_2025_1358_MOESM3_ESM.xlsx-Table_S6-DEGs_p_0_05_between_surviving_or_deceased_DLBCL_patients_that_received_R-CHOP_therapy_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
786O	DepMap CRISPR Gene Dependency	1.0	3.93506
CHD9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00488606
GTEX-R53T-0005-SM-3GADK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23221
POLR2A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
G44	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14483
H3K27ac_Brain Cingulate Gyrus	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC6815046-13073_2019_678_MOESM3_ESM.xlsx-TCF20-Unnamed_0_TCF20	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BB-4223-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posteroventral (inferior) parietal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.15902
CTCF_fibroblast of lung_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K32636001_MLS-0437446.0001_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K99522349	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32651
GSE193027_1_v_0_krt19_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AR-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-A54927599_KF 38789_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE195568_3_v_4_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE77108_6_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3942-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Dorsal peduncular area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2871
stratum radiatum of caudal CA1	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.26246
TAF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FKBP14	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.84754
parvocellular part of the r9LRt	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04135
primary auditory cortex (core)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02786
hsa-miR-4782-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.454769
GTEX-QDVJ-0005-SM-2TC5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08775
magnocellular division of VA	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.36875
BRD-K46056750_AZD-7762_SKBR3_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE101239_4_v_2_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC6344081-elife-40364-supp8.xlsx-PLZF-kd_2d_Diff_Vs_Ctrl_2d-diff-Symbol_ZBTB16	Rummagene Transcription Factor Associations 2026	1.0	null
GSE146612_1_v_0_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
WholeBlood	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-0.870496
GSE160246_9_v_1_cpeb4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE127916_1_v_4_nras_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K64935403_E0886_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K49292348	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66623
GSE115542_2_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TCF7L2_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A01593789_CHLORMADINONE ACETATE_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5360-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE198165,GSE198166_7_v_10_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pcgf2_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.614043
Perturb_17748_KO_Drd2_SRP238905	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.11293
BRD-K08702524	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63278
BRD-K48777375	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03446
SCN7A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00619142
EKVX	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.44317
GSE133087_1_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
WTAP_KD_GDS2010_69_human_HUVEC (umbilical vein endothelial cells)	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
GSE111385_0_v_1_tgfbr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE171401_1_v_0_adnp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XMD1-0011-R5A-SM-4AT47	GTEx Tissue Sample Gene Expression Profiles	1.0	0.985982
POU5F1-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
Flocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31801
hsa-miR-515-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
CTCF_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K77425312	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2317
CTCF_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89018_12_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_bronchial epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of transport	GO Biological Process Annotations 2015	1.0	null
Kidney Chromophobe_KICH_TCGA-KN-8423-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RMUG-S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.44817
GSE211128_4_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RVPU-0005-SM-2TF6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06395
principal sensory nucleus of trigeminal nerve, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.909146
ACP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00509655
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-geneName_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WZTO-0011-R6B-SM-4E3J6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27016
BRD-A37837077_C247_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_retinal pigment epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.67759
SUZ12	ENCODE Transcription Factor Targets	1.0	null
Rectum adenocarcinoma_READ_TCGA-EI-6511-01A-11R-1736-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Uterine Carcinosarcoma_UCS_TCGA-N5-A4RO-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE181966_0_v_3_has2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196671_5_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE100316_5_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
C32	CCLE Cell Line Gene CNV Profiles	1.0	2.02725
H3K4me3_epithelial cell of proximal tubule_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE152432_5_v_4_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TT	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93819
mediodorsal nucleus of thalamus_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.932289
GSE224294_1_v_2_ngly1_human	RummaGEO Gene Perturbation Signatures	1.0	null
A101D	CCLE Cell Line Gene CNV Profiles	1.0	1.72785
NRF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-WI4N-2726-SM-3LK7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.891513
Lung squamous cell carcinoma_LUSC_TCGA-96-7544-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TGIF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.7437
CTCF_GM12864_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_retinal pigment epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5260-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE214931_2_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE169152_3_v_4_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE181959_1_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NKX2-2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.7297
GSE175787_11_v_7_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
ERF::NHLH1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	45.8768
GSE195559_8_v_4_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-GC-A3RC-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_ENMD-2076 L-Tartaric acid_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0144542
JUND_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LU99	CCLE Cell Line Gene CNV Profiles	-1.0	-1.93216
BRD-K99482176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39643
hexamethonium bromide-1901	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
1351_CCT7_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.655956
CTCF_MCF-7_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226584,GSE226589_3_v_0_ezh2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158969_1_v_0_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_cardiac muscle cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00883748	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.94503
K562_M344_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0205589
VIIAt	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.909638
CTCF_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE131649_2_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
phthalylsulfathiazole-3033	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2AphosphoS5_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X5EB-2326-SM-46MW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843846
PMC6928102__F5	PFOCR Pathway Figure Associations 2024	1.0	null
choroid plexus of the lateral ventricle	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.31508
16813654-SuppFile2	GeneSigDB Published Gene Signatures	1.0	null
positive regulation of protein localization to membrane	GO Biological Process Annotations 2025	1.0	null
GSE77108_8_v_2_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE110440_1_v_3_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ST6GAL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.46469
GSE216043_7_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAD21_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE203060_0_v_1_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
CHD2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE116930,GSE116935_1_v_0_hes7_human	RummaGEO Gene Perturbation Signatures	1.0	null
CACO-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00544
POLR2A_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K33396764_-666_SKB_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE216043_7_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Lenalidomide_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.014893
CTCF_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WXYG-0005-SM-3NB3M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59613
PNT-1A cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.571
GTEX-S4Z8-0006-SM-3K2AQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30865
GSE101336_1_v_3_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE211151_1_v_4_progesterone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44731
YY1	ENCODE Transcription Factor Targets	1.0	null
PLCL1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00662843
hsa-miR-548i	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
BRD-K05704547	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77926
Acute Myeloid Leukemia_LAML_TCGA-AB-2885-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WWYW-0005-SM-3NB3K	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.61576
GSE119978,GSE180930_2_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCI-H446	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.29046
SC-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.21729
BRD-K71919612	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46394
GSE123638,GSE123639_2_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_7_v_0_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
embryonic stem no feeder	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.871802
GSE207135_1_v_0_sod2_human	RummaGEO Gene Perturbation Signatures	1.0	null
496100278_FWM_no dementia_TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.27775
H3K4me1_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-B3-A6W5-01A-12R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_NVP-BSK805 2HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0205725
GSE248858_4_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K09596790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1087
HCC4017	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983913
A549_Lomustine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0168722
GTEX-S4P3-0006-SM-3K2AW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3582
COR-L26	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.94174
GTEX-PW2O-0226-SM-48TC7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.988035
16288205-GeneTable2	GeneSigDB Published Gene Signatures	1.0	null
layer IIIu of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.12072
PMC4162954-12864_2014_6430_MOESM3_ESM.xlsx-2102Ep-Genes_deregulated_in_2102Ep_cells_after_SOX2_knock-down_FDR-corrected_P-value_0_05_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
HCC1569	CCLE Cell Line Gene CNV Profiles	1.0	1.75825
BRD-K97717496	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1911
MKN-45	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.10091
GSE183251_4_v_0_cyp2c70_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.99909
GSE211177,GSE211178_9_v_3_ets1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QDT8-0011-R7A-SM-32PKF	GTEx Tissue Sample Gene Expression Profiles	1.0	2.90725
BRD-K26122955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15465
superficial stratum of r5BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.29594
BRD-K08075712	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19512
H3K4me3_cardiac mesoderm_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE154350_1_v_0_ascl2_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1770	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.48931
regulation of cell migration	GO Biological Process Annotations 2025	1.0	null
ARID3A	ENCODE Transcription Factor Targets	1.0	null
BRD-K43240808	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45845
PMC10641274-mmc2.xlsx-FOXK1_Insulin-SYMBOL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-NPJ7-0011-R10A-SM-2I3E5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14249
GSE147662_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE165636_0_v_4_tofacitinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TP63	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.1062
Taenia tecta, dorsal part, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2871
POLR2AphosphoS5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-3026-SM-32QPM	GTEx Tissue Sample Gene Expression Profiles	1.0	0.862458
Lung squamous cell carcinoma_LUSC_TCGA-22-4593-01A-21R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K01762107	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.41127
Neuron_Brain_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
negative regulation of locomotion	GO Biological Process Annotations 2015	1.0	null
HS 695T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.08067
DNAJB4	Pathway Commons Protein-Protein Interactions	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-DZ-6133-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-TSE9-0011-R11A-SM-3DB7N	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852516
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A51R-06A-11R-A266-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75712
GSE216043_10_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SKMEL19	DepMap CRISPR Gene Dependency	1.0	2.15313
BRD-K40733000	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30935
CTCF_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Integument	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
r6 part of rostral ventromedial reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17945
striatum_16 pcw_M_12287	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.847246
Lung squamous cell carcinoma_LUSC_TCGA-52-7812-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149035_3_v_5_hepacam_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE146840,GSE146842_0_v_2_qrich1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE245270_1_v_4_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
RBPMS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2383
MYC_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8650352-JCB_202012097_DataS1.xlsx-VHL_KD_filteredProteinGroups-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
PITRM1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22746
GSE77108_6_v_9_saha_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K07011015	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.17479
GSE100102_2_v_6_cgas_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE228106_3_v_1_paclitaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZBTB17	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.4195
Nfatc1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.5755
GSE184902_3_v_0_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
cingulum bundle, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.86228
GSE189609_1_v_2_hax1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MCF7_CUDC-101_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0226207
GSE215849_2_v_1_muc1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-4663	TargetScan Predicted Conserved microRNA Targets	1.0	0.37496
CA3 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.38009
CTCF_HepG2_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_IOX2_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161552
GSE235234_2_v_3_corticosterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Fastigial nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10877
GTEX-NL4W-0006-SM-2I3GH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.2341
GSE132948,GSE132949_0_v_1_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
KCNA10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00626301
EGR1	ENCODE Transcription Factor Targets	1.0	null
RABGAP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.61455
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.981426
CTCF_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K13566078_HY-10518_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE142684_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00686945
GSE233679_6_v_0_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE133329_0_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27me3_megakaryocyte_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K69698801	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33627
NCI-H1623	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898209
A549_Ellagic acid_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0166786
H3K9ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K40927841	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.15933
SORT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00594811
ANKRD13C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26873
YY1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CA14	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00475486
H3K4me2_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-V1D1-0006-SM-3NMCE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35863
BRD-K64509231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20636
GTEX-X585-0011-R5A-SM-46MVI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.79846
GTEX-R55C-0005-SM-3GAE9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72824
PPID	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.02377
GSE209582_1_v_3_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WZTO-2926-SM-3NM9I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.894086
GSE125211_0_v_1_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Agranular insular area, dorsal part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24382
TBP_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HAPLN3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0062593
GSE216043_11_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
cortex of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.13924
SK-LU-1	COSMIC Cell Line Gene Mutation Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149903_5_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE229102_1_v_0_nr2f6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_7_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE166315_1_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MDAMB175VII	CCLE Cell Line Gene CNV Profiles	1.0	2.28726
20220088-SuppTable1	GeneSigDB Published Gene Signatures	1.0	null
GSE180377_2_v_1_lipa_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_CD19 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
18794137-SuppTable1a	GeneSigDB Published Gene Signatures	1.0	null
basal nucleus of meynert, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.1009
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6097-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210093_3_v_2_taf15_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10592471-NIHMS1912771-supplement-2.xlsx-NR2F1-Ind-Upregulated_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
positive regulation of transporter activity	GO Biological Process Annotations 2015	1.0	null
GTEX-UPK5-0006-SM-3GAD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14038
GSE210842_3_v_1_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898209
JUND_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-FU-A3NI-01A-11R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H889	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898209
H3K4me3_GM12864_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_LNCaP clone FGC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-73-4666-01A-01R-1206-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210580_4_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE231648_1_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5463-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PROK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00664346
CTCF_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_PD98059_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163409
periventricular nucleus, preoptic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.11211
H3K56ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3255	COSMIC Cell Line Gene CNV Profiles	1.0	2.09117
GTEX-QDT8-0011-R2A-SM-32PKQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909663
GSE211128_3_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE92457_9_v_10_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
trichostatin A-3058	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
FABP5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.004544
GSE153871_1_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of isBI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27818
biological_process	GO Biological Process Annotations 2015	1.0	null
GSE102505_5_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-411	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
ETS1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
AOB, internal plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25241
BRD-A14331394	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25512
BCL3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIIA, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.868435
GSE242083,GSE242098_2_v_5_med1_human	RummaGEO Gene Perturbation Signatures	1.0	null
HCC1569	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.827431
CREB1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
eed_20123906_mouse_embryonic_stem_cell_lof_mouse_gpl1261_gse19076	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.147937
mRNA_POU5F1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06539
inner portion of medial ganglionic eminence	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.825162
GSE176008_4_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
imatinib_homo sapiens_gpl96_gds3048	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_A549_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171724_4_v_6_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
FOXA1-27270436-VCAP-HUMAN-PROSTATE-CARCINOMA	ChEA Transcription Factor Targets 2022	1.0	null
PD-70-VS77_0.01uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.289114
GSE118766_2_v_3_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE203181_0_v_1_phosphoramidon_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4723-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.7397
GSE181461_1_v_4_trim28_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE147943_5_v_1_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ8-0011-R10A-SM-2YUMO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966901
EHF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0043772
GSE80537_0_v_2_adhfe1_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-2276	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
GSE138019_4_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.94009
CTCF_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM 149PT	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.28917
RCOR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_bronchial epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HUPT4	DepMap CRISPR Gene Dependency	1.0	2.39696
Taenia tecta, dorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.33168
EP300_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP2	ENCODE Transcription Factor Targets	1.0	null
GATA2_SH-SY5Y_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QESD-0006-SM-2I5G6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33218
Taenia tecta, dorsal part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.5095
GSE227592_9_v_3_adar_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_GM12891_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K36633782	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.00408
Prostate adenocarcinoma_PRAD_TCGA-EJ-5532-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CD37	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00497665
GSE94849_7_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HA-E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4328	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
Perturb_17175_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE202434,GSE202438_7_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K19106745	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2091
GSE157555,GSE157556_5_v_1_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Pracinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0141733
WM-115	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.15418
RFX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QEG5-0006-SM-2I5FZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21285
lymphnode_4b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.963708
GSE191174_0_v_1_ccdc92_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IRF1_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.58266
GSE233679_14_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE125782_3_v_1_glutamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE133070_3_v_1_prss1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
1408_CDC5L_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.571769
KARPAS-1106P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.04617
GSE180200,GSE180201_5_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
D283MED	CCLE Cell Line Gene CNV Profiles	-1.0	-1.51203
GSE112860_0_v_4_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE121198,GSE129779_3_v_2_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC11811132-41598_2025_89334_MOESM5_ESM.xlsx-MECP2-toNode_MECP2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K36me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE205163,GSE205164_2_v_0_znf808_human	RummaGEO Gene Perturbation Signatures	-1.0	null
r10 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.7427
SMC3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Raltitrexed_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0127324
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_CoCl2-Unnamed_16_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.908454
GTEX-S33H-0005-SM-2XCAL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01137
GTEX-T2IS-3126-SM-32QPK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10097
Prostate adenocarcinoma_PRAD_TCGA-EJ-7781-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_16084_KO_Nfya_SRP270915	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.98072
GSE111660_1_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE163275_1_v_0_irf8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC461	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898719
primary visual cortex (striate cortex, area V1/17)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.44731
HCC2998	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-P44H-0006-SM-2XCFB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04967
GSE239844_6_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8185471-mmc7.xlsx-DEGs-SOX15_peaks-Day_6_SOX15-_-_upregulated_and_downregulated_genes_nearby_SOX15_CUT_Tag_top_10k_peaks_Related_to_Figure6_SOX15	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_G007-LK_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132389
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
501A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.71505
BRD-K77727343	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25811
GSE218060_1_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_7_v_2_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
positive regulation of anion transmembrane transport	GO Biological Process Annotations 2025	1.0	null
MDA-MB-330	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.17697
A549_EED226_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0282786
GSE179880_10_v_3_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
thp1	HPA Cell Line Gene Expression Profiles	-1.0	-0.87049
GTEX-WZTO-0011-R4A-SM-3NMC7	GTEx Tissue Sample Gene Expression Profiles	1.0	0.910409
pralidoxime-3066	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9174882-EMMM-14-e15816-s002.xlsx-ThCell_GeneSigs-GSE24574_BCL6_LOW_TFH_VS_NAIVE_CD4_TCELL_UP_BCL6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K79554012_-666_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE200352_9_v_6_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_fibroblast of the aortic adventitia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE142210_3_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dapsone-1827	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-S4Q7-0006-SM-3K2AT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02609
3291_GATA1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.64116
thiamphenicol-1826	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC11511861-41420_2024_2216_MOESM2_ESM.xlsx-GSEA_siYAPsiTAZ-SITAZ_UP__MYC_EZH2_H3K27M3BOUND_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7261-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
EP300_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216538_7_v_2_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-Q2AH-0126-SM-48U2B	GTEx Tissue Sample Gene Expression Profiles	1.0	1.11362
BRD-K92913380	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0978
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A8YO-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE163240_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HNF4G	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-3140-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
BRD-K27354087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.66431
GSE158197_5_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_spleen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE199899_4_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NFK9-0006-SM-3GACS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2232
GTEX-U4B1-0006-SM-3DB8E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19466
H3K4me3_cerebellum_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
A549_KW-2449_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0173445
A549_Zileuton_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155376
PMC11257629-media-9.xls-METTL3_KD_upregulated_Genes-METTL3KD_UPregulated_Genes_1694_AR	Rummagene Transcription Factor Associations 2026	1.0	null
SARS-BatSRBD_36Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.0199
GTEX-PVOW-2626-SM-32PL8	GTEx Tissue Sample Gene Expression Profiles	1.0	0.922304
GSE142210_2_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_17176_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-UTHO-0011-R6A-SM-3GIJW	GTEx Tissue Sample Gene Expression Profiles	1.0	2.44648
H3K4me3_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SECISBP2L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03678
globose nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.21752
MAX_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23984367_sorafenib_HEPG2_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE217405_3_v_2_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CRYZ	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.21256
BRD-K74138110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07328
496100448_TCx_possible Alzheimer's disease_no TBI_88_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.07404
PMC5848610-supp_gr.228809.117_Supplemental_Table_S4.xlsx-Table_S4D-Supplemental_Table_S4D_List_of_differentially_expressed_genes_upon_siZFX_with_promoters_bound_by_ZFX_in_C42B_ZFX	Rummagene Transcription Factor Associations 2026	1.0	null
Cerebellum	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.236
GSE186647,GSE217288_11_v_7_hnrnpc_human	RummaGEO Gene Perturbation Signatures	1.0	null
DUX4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01953
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-6093-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-M16762496_S1205_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
regulation of protein localization	GO Biological Process Annotations 2015	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6392-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164757,GSE164759_4_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
TCF12_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML	ENCODE Transcription Factor Targets	1.0	null
NEK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00595153
BRCA1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE238018_3_v_5_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
RAX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5471
C3A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.910552
Brain Lower Grade Glioma_LGG_TCGA-HT-7610-01A-21R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-5681-01A-11R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
positive regulation of protein targeting to membrane	GO Biological Process Annotations 2025	1.0	null
PMC11193738-41467_2024_48647_MOESM8_ESM.xlsx-Data_S5-Data_S5_HNF4A-bound_gene_targets_identified_from_ChIP-Seq_in_hepatic_cells_D8_Hep_and_HepG2_cells_HNF4A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE226316_4_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE100316_5_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CREB1	ChEA Transcription Factor Targets	1.0	null
BRD-K38935430	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85336
CTCF_brain microvascular endothelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative regulation of cell motility	GO Biological Process Annotations 2023	1.0	null
H2AFZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133087_5_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
LS123	DepMap CRISPR Gene Dependency	1.0	3.95411
Nfat5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	23.764
GSE183335,GSE183351_3_v_0_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
Plasma membrane	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
20436685-ST6-2	GeneSigDB Published Gene Signatures	1.0	null
Anterior cingulate area, dorsal part, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27818
EXOSC10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00556452
BRD-K85162396	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06318
GSE216043_10_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
EP300_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K81956993	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.10964
GATA2	JASPAR Predicted Transcription Factor Targets	1.0	null
HS683	CCLE Cell Line Gene CNV Profiles	1.0	1.38108
1,4-chrysenequinone-1773	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BL7872 (RAPGEF6)	NURSA Protein Complexes	1.0	null
H3K27ac_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
establishment of localization	GO Biological Process Annotations 2015	1.0	null
GSE149880_0_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SIRT6	ENCODE Transcription Factor Targets	1.0	null
K562_Baricitinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0185025
GTEX-X4XX-0011-R11A-SM-46MWQ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.938929
Folium-tuber vermis (VII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42896
dorsolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.90828
H3K4me3_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF7_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OXRN-1726-SM-3NM9B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.904088
A549_Quercetin_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132252
15260889-TableS2a	GeneSigDB Published Gene Signatures	1.0	null
znf148_21828133_erythroblast_lof_human_gpl571_gse31092	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.48732
hsa-miR-1236	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.40969
lateral hypothalamic area, anterior region, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.868936
H3K4me3_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HOXB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.65988
OUMS-23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941778
HCC2688	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898018
GTEX-XQ3S-1126-SM-4BOPK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94018
mRNA_ESX1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-K72591075	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26977
BRD-K77250455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.058
HCC1359	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
BRD-K35424586_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
osteoclasts	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.844643
BRD-K64953645	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37324
Perturb_1724_KO_Tet2_SRP353433	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	11.9644
GSE122101,GSE122103_3_v_4_ssu72_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE207863_0_v_1_hdac5_human	RummaGEO Gene Perturbation Signatures	1.0	null
rostral ventrolateral reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03439
H3K4me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE157777_1_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Central amygdalar nucleus, lateral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23564
NR2F2_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE144838_1_v_5_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBL4A	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me3_HEK293_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_Lapatinib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0139718
positive regulation of anion channel activity	GO Biological Process Annotations 2025	1.0	null
17284527-TableS2	GeneSigDB Published Gene Signatures	1.0	null
hsa-miR-3121-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.241055
H3K4me1_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HAND2-30127528-KELLY-HUMAN-BRAIN-NEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
BRD-K16330310	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15575
ERI1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0052456
PAPOLB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.36309
Bladder Urothelial Carcinoma_BLCA_TCGA-GV-A3QI-01A-11R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_fibroblast of villous mesenchyme_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RFX5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE193993_4_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Hic1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	21.7838
posterior (caudal) superior temporal cortex (area 22c)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.30139
hsa-miR-548c-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
ZNF143	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.3882
MZ in rostral midinferior temporal cortex (area 36)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.846298
Head	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K66902379_MLS-0435526.0001_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE211128_9_v_8_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133070_2_v_4_prss1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5454-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ccnd1_18413728_imr_neuroblastoma_lof_human_gpl570_gse8866	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.060778
superficial stratum of r9BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.87991
medioventral part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.91762
H3K4me3_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K08799216_pelitinib_BT20_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE142684_2_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MYC_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3ac_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K94444134	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.20198
ALX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.658
lateral hemisphere of cerebellum	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.876994
A549_Roscovitine_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0110676
GEM	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00582309
CTCF_GM12872_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OGDH	Pathway Commons Protein-Protein Interactions	1.0	null
GSE228181_0_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSTP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.45137
Cortical amygdalar area, posterior part, lateral zone, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17625
GSE235516_0_v_1_zdhhc2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216043_7_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r7 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.73992
ELF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE60691_0_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MHH-NB-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.23728
BRD-K49184477	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.31298
GSE119498_0_v_10_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Field CA3, stratum lacunosum-moleculare	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02728
CTCF_astrocyte of the spinal cord_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K67525206	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.69103
GSE242096,GSE242098_1_v_0_med1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
E2F4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DUX4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.39
PMC7062471-elife-52504-supp6.xlsx-TEAD4_motif_in_OCR_around_DEGs-Gene_ID_TEAD4	Rummagene Transcription Factor Associations 2026	1.0	null
IGFBP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00391125
BRD-K39020351	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19712
GTEX-XOTO-0526-SM-4B662	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.915295
SUM185PE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.887181
GTEX-NL3H-0006-SM-2I3FW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42274
K562_SB431542_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136973
BRD-A84481105_thioridazine_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_GM12872_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUN	ENCODE Transcription Factor Targets	1.0	null
endometrium_5a	HPA Tissue Sample Gene Expression Profiles	1.0	0.985638
eGFP-JUNB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NPJ8-0007-SM-2D7VX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34661
H3K4me3_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XPT6-2026-SM-4B64V	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.840384
plexiform layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42529
EBF1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216043_7_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XLM4-0011-R6A-SM-4AT4B	GTEx Tissue Sample Gene Expression Profiles	1.0	2.64082
GTEX-REY6-0005-SM-2TF54	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01384
BRD-K56057104	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23471
A549_Azacitidine_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0145976
SP1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE122215,GSE122217_0_v_2_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of skin of abdomen_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSMM	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.13029
NOA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10669
SKP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.00484
EZH2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226249_0_v_6_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
COV413B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888368
TLX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.5306
ITCH	Pathway Commons Protein-Protein Interactions	1.0	null
TSPOAP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0053468
icSARS CoV_60Hour_None_GSE37827	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.63709
PMC9377669-tx1c00392_si_002.xlsx-Famotidine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_keratinocyte_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.995254
GTEX-T6MN-0005-SM-32PLJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31842
Bladder Urothelial Carcinoma_BLCA_TCGA-CU-A3KJ-01A-11R-A21D-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TCF4	MotifMap Predicted Transcription Factor Targets	1.0	null
hsa-miR-4715-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
dexamethasone_homo sapiens_gpl6244_gse20963	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-Q2AG-0005-SM-33HBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.10112
AG-028671-6587	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TCF7L2	ENCODE Transcription Factor Targets	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5879-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
20436685-ST4-1	GeneSigDB Published Gene Signatures	1.0	null
prepositus hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.10073
K562_Glesatinib(MGCD265)_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0139551
BRD-K06480376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11278
GSE210580_0_v_1_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB	ENCODE Transcription Factor Targets	1.0	null
GSE44461_1_v_0_tcf21_human	RummaGEO Gene Perturbation Signatures	1.0	null
IRAK1	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_BE2C_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11495544-JPN-240026-at-2.pdf-165-NFIB_NFIB	Rummagene Transcription Factor Associations 2026	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JV-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RNF168	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00632456
H3K4me3_WERI-Rb-1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7331-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BAG3	Pathway Commons Protein-Protein Interactions	1.0	null
GSE246053_1_v_3_hnf4a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
amygdaloid complex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-2.3372
SIN3A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE201239_0_v_1_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH2073	CCLE Cell Line Gene CNV Profiles	-1.0	-1.66888
NCM-460 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.67
Uvula (IX), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.09802
GSE163052,GSE163198_1_v_0_hira_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_HL-60_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MCF7_INO-1001_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0101232
BRD-K86463534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07732
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.2329
substantianigra	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.944906
POLR2A_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Levothyrox-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GSE157555,GSE157556_4_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cingulum bundle, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-2.40297
GTEX-SNMC-0006-SM-2XCFE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12222
CCNH	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8181
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05851
embryonic stem feeder layer	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	-1.0	-0.96032
ELF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT4	MotifMap Predicted Transcription Factor Targets	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOXA1_T47D_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LI7	DepMap CRISPR Gene Dependency	1.0	2.00229
GSE120612_7_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_GM12875_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE211126_3_v_4_hapln1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_Jurkat_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CALCRL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00624487
GTEX-NPJ7-0011-R8a-SM-2I3G2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.08802
GSE152432_3_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC10928104-41419_2024_6576_MOESM4_ESM.xlsx-S14-FOXM1_targets_FOXM1	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H295R cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.607
CTCF_WI38_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-90-A4ED-01A-31R-A24Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
mantle zone of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.34102
H3K4me3_B cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4EO-0006-SM-3P5ZF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978143
GSE209601_2_v_1_mef2a_human	RummaGEO Gene Perturbation Signatures	1.0	null
Copula pyramidis, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07531
CTCF_GM12869_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RGPD6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34323
BRD-K71726959_N9-ISOPROPYL-OLOMOUCINE_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K04887706_AKT-inhibitor-1-2_HT29_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
7754_SEC62_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	-1.0	-0.515523
K562_Givinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0149973
MCF7_AICAR_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0135817
BRD-K17199106	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91358
H3K4me3_LNCaP clone FGC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Flocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.36282
MIXL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5873
GTEX-X5EB-0006-SM-46MV5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.18765
BRD-K71799778_BML-259_SNGM_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE248045,GSE248046_6_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
5677_NIPBL_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.511897
CTCF_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B8-5545-01A-01R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27ac_CD4+ CD25- CD45RO+ Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K98968761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06742
H2AFZ_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K28565184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36269
GTEX-WHSE-3126-SM-3P5ZI	GTEx Tissue Sample Gene Expression Profiles	1.0	0.931726
CD40	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00355257
CYB561D1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.98696
GSE169356_0_v_4_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K77681376_2-morpholino-N-((4-nitro-1H-benzo[d]imidazol-2-yl)methyl)-9-(thiophen-3-yl)-9H-purin-6-amine_HCC515_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SKP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0067193
GSE129153_0_v_1_forskolin_human	RummaGEO Drug Perturbation Signatures	1.0	null
superficial stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41848
CTCF_foreskin fibroblast_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZH-0005-SM-2HMJN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80002
PFSK-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.95887
GSE178340_5_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
IZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.919186
CTCF_GM12870_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0005-SM-2YUML	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.14085
BRD-K03601405_NCGC00242337-01_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6410-01A-11R-1896-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE141726,GSE141733_1_v_0_angiotensin ii_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
EFNA2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.62236
MPV17L2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41834
GSE119978,GSE180930_2_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-TML8-0005-SM-32QPA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.33372
RAJI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.95543
HKDC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00536351
GSE215314_0_v_1_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
metacycline-2901	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CLEC12B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00548108
H3K4me1_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
E2F6_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-TSA-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GTF2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC5889290-koni-07-04-1412909-s001.xlsx-GSC-exo_vs_Fibro-exo_stat_sign-Gene_name_GSC	Rummagene Transcription Factor Associations 2026	1.0	null
BAD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00555772
GSE207611,GSE207612_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-A4-7288-01A-11R-A32Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE185635_0_v_1_ncor1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
AQP11_Deficiency_GDS3395_578_mouse_Kidney	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
C1orf116	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.33518
GSE158197_0_v_4_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
regulation of localization	GO Biological Process Annotations 2015	1.0	null
ARHGDIB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0053384
GTEX-W5X1-0006-SM-3GIJZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00213
H3K9ac_Rectal Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE132948,GSE132949_0_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TAF1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Curcumin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0259485
external part of AOV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.40838
BRD-K50272743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96187
CTCF_GM19238_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MAX_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC11067031-pnas.2317690121.sd05.xlsx-Sheet1-Differentially_expressed_genes_between_PML_RARA_GFP_vs_Empty_vector_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K23547378	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.68881
GTEX-XYKS-0926-SM-4BRVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31638
GTEX-T5JC-0005-SM-4DM7B	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51284
U266B1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0691
NEDD8	Pathway Commons Protein-Protein Interactions	1.0	null
SNAPC4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00509297
GTEX-R55E-0011-R4A-SM-2TC5H	GTEx Tissue Sample Gene Expression Profiles	1.0	0.877141
CTCF_fibroblast of pulmonary artery_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
locus ceruleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.22631
CBX3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DMS 53	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01446
GTEX-XPVG-0006-SM-4B65Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.69968
GSE181521_0_v_1_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Lomustine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0202216
HMGN3	ENCODE Transcription Factor Targets	1.0	null
BRD-K06529600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2713
GSE199899_1_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
positive regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GSE157555,GSE157556_4_v_2_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-QDVN-0006-SM-48U1R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.92363
GSE241701_2_v_0_daxx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216273,GSE216292_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-N7MS-0426-SM-2YUN6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.918351
BAG6	Pathway Commons Protein-Protein Interactions	1.0	null
Infralimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.80894
GTF2F1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K12492021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23944
Disease of cellular proliferation	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.081
GTEX-Q2AI-0006-SM-2I3FG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.62209
GSE248858_6_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
HDGFL2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.12508
Prostate adenocarcinoma_PRAD_TCGA-CH-5753-01A-11R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE128844_0_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	1.0	null
PHF8	ENCODE Transcription Factor Targets	1.0	null
ABCC9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00540433
BRD-K90027990	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26062
HNF4A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174735_4_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22715231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10754
GTEX-WZTO-0011-R8A-SM-4E3II	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27975
ctnnb1_19652203_myeloma_lof_human_gpl570_gds3578	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.126953
GSE229973_4_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27me3_G1E_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A75931230_F1061-0166_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7994-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLHL5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00519051
BRD-K29458283_chlorambucil_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.14625
REST_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STAT5A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Schaffer collateral - CA1 synapse	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.912
H3K4me3_cardiac mesoderm_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K83294522	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58384
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Unnamed_1_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
CORL311	DepMap CRISPR Gene Dependency	1.0	2.10057
GNB5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03082
GSE166315_5_v_4_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PD-70-VS77_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.265023
GTEX-QLQW-0005-SM-2S1RA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16063
POLR2AphosphoS5_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
whole body	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.23362
COLO-668	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.01219
4944_MED21_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.582694
Gustatory areas	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53077
Perturb_241_KD_Blimp1_SRP094038	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GTEX-RU72-0011-R6A-SM-2TF71	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15526
GTEX-S95S-0005-SM-2XCEC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1223
GTEX-PWO3-0011-R5A-SM-2I5EZ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861648
TAF1	ENCODE Transcription Factor Targets	1.0	null
BRD-A60245366_AS-601245_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE219195_1_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_2_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12873_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DBTRG05MG	DepMap CRISPR Gene Dependency	1.0	3.57369
OVMANA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.51887
POLR2A_GM12892_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUM52PE	DepMap CRISPR Gene Dependency	1.0	2.61198
MCF7_Costunolide_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00936581
primary somatosensory cortex (area S1, areas 3,1,2)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.901503
H3K4me3_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
MEIS1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	35.1761
TAL1::TCF3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.4773
H3K9ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE147876,GSE147877_2_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE163297_0_v_2_doxorubicin_human	RummaGEO Drug Perturbation Signatures	1.0	null
OCI-AML2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.18515
H3K4me3_GM12865_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE70935_1_v_0_cyfip1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KEL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00467266
CTCF_fibroblast of lung_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K22878149_sb 205607_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GP5d	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.2013
H3K36me3_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4	ENCODE Transcription Factor Targets	1.0	null
GSE160001,GSE160670_0_v_2_lapatinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
POLR2A_limb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218060_2_v_4_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE195559_6_v_1_notch1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SP2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 675.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.69214
POLR2A_erythroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE103068_0_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me2_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RIT2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00496176
BRD-K60558601	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03917
orbital frontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34901
GSE151612_0_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
Copula pyramidis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.07622
hsa-miR-499-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
CTCF_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K07615667	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92091
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.55828
POLR2A_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZG-1326-SM-2HMIQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.903075
YY1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UJHI-0006-SM-3DB8H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02834
internal granular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20518
GSE227891_2_v_0_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_6588_KO_Cabin1_SRP252595	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.7246
dorsolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.92635
GSE179002_2_v_7_caprin1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_medulloblastoma_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCoV-EMC2012_24Hour_23631916_GSE45042	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.19763
GSE73381,GSE73382_0_v_1_hira_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BHLHE40_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OVCA420	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.14047
GSE103068_5_v_3_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
EGFR_UP.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
H3K27ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
NUGC2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.9975
GATA3	ENCODE Transcription Factor Targets	1.0	null
1650_CLEC2D_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.55048
CTCF_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inner CP in temporal polar cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.37619
H3K4me3_BJ_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_bone marrow macrophage_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Neurosphere Cultured Cells Cortex Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE156708_1_v_0_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4728-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GSE119498_6_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
parasubicular cortex (parasubiculum)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.990155
BRD-K28545166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0761
BRD-K11823863	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10343
L33	CCLE Cell Line Gene CNV Profiles	-1.0	-1.45143
A549_Valproic acid sodium salt_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014834
GSE135514_8_v_0_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K41717398	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08021
Uterine Carcinosarcoma_UCS_TCGA-NA-A4R1-01A-11R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
TBL1XR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
LBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.4952
CLECL1P	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00541851
DPPA5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.26113
CTCF_GM06990_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3921_KD_VPS37A/VPS37B/VPS37C_SRP266781	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-10.4312
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.13722
GTEX-U3ZM-0226-SM-4DXTA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.31832
GTEX-XUZC-2126-SM-4BRW8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.910269
ADAMTS5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00375789
GLS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00732645
GTEX-WYVS-0006-SM-3NMA7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23919
transient Purkinje cell clusters	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.40301
BRD-K76482408	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23731
UBTF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
gallamine triethiodide-1375	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Lobules IV-V	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08534
REST_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-8205-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
6258_PGK1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.53359
anterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.97875
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1IC-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
brain_a	HPA Tissue Sample Gene Expression Profiles	1.0	1.05345
Spinal cord	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.088
GTEX-U412-0326-SM-3DB9L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.909944
BRD-K09528868	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80402
FOXM1	ENCODE Transcription Factor Targets	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.10479
GSE179880_4_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF416	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1246
RUNX1-21571218-MEGAKARYOCYTES-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
TAF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-UPJH-0526-SM-4IHK8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.941931
KCNMB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00582382
H3K4me3_C2C12_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
hl60	HPA Cell Line Gene Expression Profiles	-1.0	-2.19594
fulvestrant-6165	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
positive regulation of ion transport	GO Biological Process Annotations 2015	1.0	null
LN-18	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PE01	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12542
BRD-A41692738_TGX-221_MDAMB231_3_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE118766_1_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-B4-5378-01A-01R-1503-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
DIXDC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.04226
GTEX-UJMC-0226-SM-4IHLH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01668
Periventricular hypothalamic nucleus, posterior part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.08553
KARPAS-620	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.17977
GSE120413,GSE120447_0_v_2_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC3607232-mmc3.xlsx-a_RUNX1_SEM_MLLN_AF4C_H3K79Me-x_RUNX1	Rummagene Transcription Factor Associations 2026	1.0	null
RERF-GC-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.12591
Prostate adenocarcinoma_PRAD_TCGA-J4-8198-01A-11R-2263-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A99518825_STOCK4S-23872_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-XOT4-0005-SM-4B64S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13313
496100409_FWM_no dementia_TBI_85_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03003
striatum_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.68251
CTCF_GM12801_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE211128_3_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
animal	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
hsa-miR-4457	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GSE233548_2_v_0_plscr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
OTUD7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8295
BRD-A80960055_3203_HEPG2_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-95-7562-01A-11R-2241-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
placenta_6a	HPA Tissue Sample Gene Expression Profiles	1.0	1.68705
hsa-miR-4478	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
H3K4me1_Neurosphere Cultured Cells Ganglionic Eminence Derived	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE169356_0_v_1_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11067031-pnas.2317690121.sd06.xlsx-gene_list_14_txt-Differentially_expressed_genes_between_PML_RARA_GFP_vs_C88A_PML_RARA_GFP_human_hematopoietic_cells_at_day_7_by_single_cell_RNA-seq_RARA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE161295_2_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
dexibuprofen-3094	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
COIL	Pathway Commons Protein-Protein Interactions	1.0	null
ZNF282	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	37.2968
regulation of transporter activity	GO Biological Process Annotations 2015	1.0	null
GSE233679_5_v_8_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K9ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X585-0011-R3B-SM-46MVG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21135
Folium-tuber vermis (VII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.52548
Female reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
CTCF_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_2022_KO_Kmt2c_SRP283007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.86134
H3K4me3_skeletal muscle cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K65913831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.79901
CA2 field, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.71378
TAF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE253089_0_v_1_ephb2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.07564
Cul3-RING ubiquitin ligase complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.997
GSE147943_2_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR2F2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180200,GSE180201_3_v_0_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MEL-JUSO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
SW 948	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.945397
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29W-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Perturb_1725_KO_Tet2_SRP353433	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.5673
MAFF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
primary motor cortex (area M1, area 4)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.84403
blood	GTEx Tissue Gene Expression Profiles	-1.0	-2.10021
GSE158834_10_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ	ENCODE Transcription Factor Targets	1.0	null
CAL-120	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.24741
GSE211931_2_v_3_ncoa4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ventrolateral prefrontal cortex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.03426
H3K4me1_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CBX3_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAZ	ENCODE Transcription Factor Targets	1.0	null
GSE158632_2_v_5_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
body of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.99202
SK23	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.888368
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_13_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
EGR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ME-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854919
facial nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.53063
BRD-K51575138_TPCA-1_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE226249_0_v_4_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RBM28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	4.44253
H6PD	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00646931
GTEX-PLZ4-0006-SM-2S1NY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.0732
GSE179031_0_v_2_foxp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-TMMY-0126-SM-4DXTP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.88657
GSE222758_0_v_3_clofazimine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of pulmonary artery_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ATF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE184892_6_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
Primary somatosensory area, upper limb, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.63916
H3K27ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WVLH-0011-R5A-SM-3MJFW	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47901
H3K4me3_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE134029_3_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
HUNS1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43756
hsa-miR-4286	TargetScan Predicted Conserved microRNA Targets	1.0	1.45615
BRD-A64523751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05651
GSE205163,GSE205164_9_v_7_znf808_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bed nuclei of the stria terminalis, posterior division, strial extension	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0135
BRD-A75607876	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.8026
JHH1_LIVER	CCLE Cell Line Proteomics	1.0	3.15525
anterior (rostral) cingulate (medial prefrontal) cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02472
primary auditory cortex (core)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.962929
RAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	19.103
todralazine-1799	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
positive regulation of intracellular transport	GO Biological Process Annotations 2015	1.0	null
H3K4me3_A549_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
PA-TU-8902	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.35647
496100616_FWM_no dementia_TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.28916
Sarcoma_SARC_TCGA-K1-A42X-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Adrenocortical carcinoma_ACC_TCGA-OR-A5JR-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-QVJO-0011-R5A-SM-2S1QM	GTEx Tissue Sample Gene Expression Profiles	1.0	2.39655
POLR2A_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TFAP4	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4001
GSE149621_2_v_1_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
chloramphenicol-1795	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
NT5DC2	Pathway Commons Protein-Protein Interactions	1.0	null
hsa-miR-654-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CREB3L1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.4273
H3K9ac_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
KCTD19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09583
6625_PPIE_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.692849
1778_COPS2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.600177
H3K36me3_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE115395_2_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE142210_2_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE93124_0_v_1_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Atrovastatin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A21524347	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.21409
GSE178340_5_v_6_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PDE2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00733158
SUM102PT	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.991461
Fruit consumption	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.730103
GTEX-WY7C-0006-SM-3NB3L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.13628
GSE202434,GSE202438_2_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC8390679-41467_2021_25186_MOESM5_ESM.xlsx-PBX3-Unnamed_3_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
liminal reticular formation of m2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07066
GSE191015_0_v_3_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EZH2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_MCF-7_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VAX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.4452
GSE183413_1_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE157894_2_v_0_cystine_human	RummaGEO Drug Perturbation Signatures	1.0	null
positive regulation of protein transport	GO Biological Process Annotations 2015	1.0	null
GTEX-QVJO-0011-R10A-SM-2S1QJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53284
BRD-K76558091	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18534
Parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.19161
GTEX-PWCY-1326-SM-48TCU	GTEx Tissue Sample Gene Expression Profiles	1.0	0.954632
SF-21 cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.999
GBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.2121
BRD-K04853698_LDN-193189_MCF10A_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE200352_9_v_3_pparg_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE133927_1_v_3_meox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Mitochondrion	COMPARTMENTS Experimental Protein Localization Evidence Scores 2025	1.0	1.441
inferolateral temporal cortex (area TEv, area 20)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.51887
BRD-K28346421_rifapentine_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K74305673_IMD 0354_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K89900384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81514
SP1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PBX3	ENCODE Transcription Factor Targets	1.0	null
GSE148695,GSE167284_2_v_1_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233049_1_v_3_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SKMEL5_SKIN	CCLE Cell Line Proteomics	1.0	2.06897
GSE147943_0_v_3_cited2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Mesangial cell_Kidney_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE158431_2_v_0_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MTA3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SP1	ENCODE Transcription Factor Targets	1.0	null
BRD-K10640729	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.55857
CTCF_GM12866_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
srf_20709909_hematopoietic_stem_cell_lof_mouse_gpl1261_gds3732	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.724676
IM-95M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.60934
GTEX-X585-0011-R8A-SM-46MUX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.75131
GSE201309_1_v_0_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ARID3A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_4_v_0_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
ELF1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-578	TargetScan Predicted Conserved microRNA Targets	1.0	0.205675
GSE158834_0_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_Abexinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014245
MBD4_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
U-2 OS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18441
PNPT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12555
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4967-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K71612465	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10587
TAL1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE161295_0_v_5_cdk8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
5808_NRBF2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.636199
MDA-MB-436	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.86142
Kidney Chromophobe_KICH_TCGA-KL-8345-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70183558	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35372
GSE158834_7_v_4_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100527_FWM_possible Alzheimer's disease_no TBI_90-94_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-3.09583
sulfabenzamide-2159	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K45762887	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03562
GSE184892_4_v_1_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
G292CLONEA141B1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.32807
BT474	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.724051
CRCGN016_MCF10A.WT.HP_24H:G10	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.02938
spinal (inferior) vestibular nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.847123
COLO849	CCLE Cell Line Gene CNV Profiles	1.0	1.64351
Primary somatosensory area, barrel field, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06083
BRD-K87967738	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28245
H3K4me3_fibroblast of skin of abdomen_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE178255_1_v_6_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Adrenocortical carcinoma_ACC_TCGA-PK-A5H9-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZBTB7A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4973-01A-01R-1334-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
15897907-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
GSE210101,GSE210114_11_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC9314667-Table_1.xlsx-Regulons-E2F1_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
PMC5840266-41598_2018_22384_MOESM13_ESM.xlsx-RNF181_KD_significant-Unnamed_23_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE216273,GSE216292_0_v_1_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5303304-13073_2017_407_MOESM5_ESM.xlsx-mycn-sy5y-se_single_24DMSO_vs_4-Table_S4_Genes_differentially_expressed_by_48h_Dox_MYCN_overexpression_treatment_DE_comparison_with_SY5Y-MYCN_control_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WZTO-0011-R7B-SM-4E3IS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05068
BRD-K46413323	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.40288
18535662-TableS2c	GeneSigDB Published Gene Signatures	1.0	null
GSE208634_1_v_2_doxycycline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4303_KO_Serpine1_SRP179032	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.76435
SMC1A	Pathway Commons Protein-Protein Interactions	1.0	null
GSE195568_1_v_10_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
T-47D	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984588
GSE230329_0_v_3_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE225869_1_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Andarine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0203185
RELA_GM19099_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SIN3A_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-OV-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.64101
SP in entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.89116
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.07866
RAD21_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00527366
benzocaine-2167	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
medial septal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.934373
HNF4A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-223	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
MYC_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.933754
SPIRE2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00671422
NEUROG2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	30.2742
H3K4me3_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R5A-SM-32PKT	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02202
GSE221327_10_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TBL1XR1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K89760040	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00255
GSE137325_3_v_0_copanlisib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM28	ENCODE Transcription Factor Targets	1.0	null
MYBL2	ENCODE Transcription Factor Targets	1.0	null
496100494_HIP_no dementia_TBI_100+_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.49492
PMC4196925-pone.0109760.s005.xlsx-Supp_Table_1_Genes_in_immune_mo-MLL_mod_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
Crus 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.93681
HDAC2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Reproductive system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GTEX-WWYW-0011-R11A-SM-3NB38	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02774
H3K4me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4PQ-0005-SM-2HMKJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.25397
GSE164135,GSE164137_0_v_1_fbxw7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE159148_0_v_1_sdc1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ANKRD13A	Pathway Commons Protein-Protein Interactions	1.0	null
HCC1428	DepMap CRISPR Gene Dependency	1.0	3.43358
GSE112860_0_v_1_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GM2345	BioGPS Cell Line Gene Expression Profiles	1.0	1.05455
GTEX-X585-0011-R1B-SM-46MVE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07773
GSE223609,GSE223610_0_v_1_kdm6a_human	RummaGEO Gene Perturbation Signatures	1.0	null
HAPLN3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.41851
H3K4me3_fibroblast of foreskin _hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mRNA_ASCL1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
KURAMOCHI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.2332
PMC10313373-jci-133-164637-s072.pdf-22-PBX3_PBX3	Rummagene Transcription Factor Associations 2026	1.0	null
CEBPD_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157777_2_v_0_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KLF4-19030024-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.28891
BRD-K28907958_-666_A375_24.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE184892_6_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
Kidney Chromophobe_KICH_TCGA-KO-8406-01A-11R-2315-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE166169_2_v_3_elp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsal thalamus_12 pcw_F_12835	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.45478
FLNC	Pathway Commons Protein-Protein Interactions	1.0	null
TCF12	ENCODE Transcription Factor Targets	1.0	null
GATA3	JASPAR Predicted Transcription Factor Targets	1.0	null
GSE180185_7_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FGFR1_mutant_25_GDS4046	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.17407
FOSL2	ENCODE Transcription Factor Targets	1.0	null
GTEX-WHPG-0006-SM-3NMBV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.91907
GTEX-RWSA-0005-SM-2XCAO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1636
GSE157777_1_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
cell part	GO Cellular Component Annotations 2015	1.0	null
GTEX-OXRN-0005-SM-2I5EU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.42637
GSE195514_0_v_1_stk25_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Prdm5	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.9716
GSE115542_5_v_1_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K97298761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52594
GTEX-WHWD-0005-SM-3LK7D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31354
RPMI 8226	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.998908
H3K9me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MXI1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A3AB-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE149355_0_v_1_esrp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
YY1_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE203362_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE167218_1_v_0_hoxd12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7647-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2A_brain_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PK-45P	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.90808
H3K4me1_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Lymphoid Neoplasm Diffuse Large B-cell Lymphoma_DLBC_TCGA-FA-A4XK-01A-11R-A31O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-2Y-A9GU-01A-11R-A38B-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
USF1	ENCODE Transcription Factor Targets	1.0	null
Perturb_423_KO_TAF15_SRP388817	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-6.1797
GSE149359_3_v_1_asap2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE216273,GSE216292_14_v_2_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_BRD4770_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0174027
BRD-K41089262	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.85761
GSE163240_3_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF143_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K44781836	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06804
BRD-K31490008	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52201
POLR2AphosphoS5_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TMMY-0005-SM-33HBN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00369
PMC3636213-pgen.1003459.s012.xlsx-Sheet1-KD_3_AR	Rummagene Transcription Factor Associations 2026	1.0	null
CUX1	ENCODE Transcription Factor Targets	1.0	null
BRD-K59058747_Acetylcysteine_PC3_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE149903_3_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
subparafascicular nucleus of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.47018
H3K4me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K25103635	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51723
GSE142210_3_v_6_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-QCQG-0126-SM-48U27	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34072
FOXA2	ENCODE Transcription Factor Targets	1.0	null
OAZ3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00580327
BRD-K09450441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.74525
GSE120336_0_v_2_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE126463_1_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE188870,GSE188871_1_v_3_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE48812_11_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE188870,GSE188871_1_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OIZH-1326-SM-3NB1H	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27206
K562_Ramelteon_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165224
Anterior olfactory nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13037
Perturb_17174_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
STAT3_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE256181_2_v_0_etv2_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K75207324	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19254
Lingula (I)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.67093
PEG10	Pathway Commons Protein-Protein Interactions	1.0	null
GSE207122_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-POMQ-1926-SM-3NB1Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862546
BRD-K59250830	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10134
Viscus	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
6625_PPIE_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.74611
GSE89018_11_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
IV, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.02946
GTEX-XPVG-0008-SM-4GICH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.858081
FOXA1_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE189683_1_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NFYB_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-219-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.419947
Disease of anatomical entity	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.133
KCTD10	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K05635176	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31313
ATP5MGL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.18078
SAP30_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
GSE173262_2_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961868
YY1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF143	ENCODE Transcription Factor Targets	1.0	null
GTEX-WL46-0011-R6A-SM-3LK6X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.856697
GSE154197_1_v_0_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
Bed nucleus of the accessory olfactory tract	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.87134
intermediate stratum of SePal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12266
ar_21330406_lncap_lof_human_gpl570_gds4113	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.337568
Renal glomerular cell line	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.807
ALG5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.632
ZNF217_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12870_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
paclitaxel_homo sapiens_gpl570_gse39042	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_astrocyte of the spinal cord_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SH3BP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00392012
GSE159473_0_v_1_eif5a2_human	RummaGEO Gene Perturbation Signatures	1.0	null
HESX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6682
GSE126463_6_v_2_pomalidomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Hand1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	39.2542
Crus I, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.53712
Cortical amygdalar area, anterior part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04489
GRIN2C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00606987
Perturb_15594_KD_PPARG_SRP049523	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	20.0
GSE218580_1_v_5_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
K562_Quercetin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0147706
ZNF263	ENCODE Transcription Factor Targets	1.0	null
BRD-K64922699	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27516
positive regulation of ion transmembrane transporter activity	GO Biological Process Annotations 2025	1.0	null
MV-4-11	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3954
PMC12354803-42003_2025_8643_MOESM2_ESM.xlsx-2w_TP63_positive-Gene_TP63	Rummagene Transcription Factor Associations 2026	1.0	null
JHOM2B	CCLE Cell Line Gene CNV Profiles	1.0	1.62217
Perturb_17736_KO_Ikkb_SRP315113	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.12288
H3K4me3_ES-E14_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-WL46-0011-R5A-SM-3LK6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.40037
regulation of protein targeting to membrane	GO Biological Process Annotations 2023	1.0	null
GSE166004_5_v_4_pld1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K68143200_-666_SW620_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
layer 1 of VPrP cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3068
GSE60837_2_v_3_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_keratinocyte_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hippocampus (hippocampal formation)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-2.33245
Paramedian lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28207
Prelimbic area, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.34883
polysensory temporal cortex (area 22p)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.938169
hsa-miR-548b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
tolfenamic acid-1437	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Uniplex complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.533
mediodorsal nucleus of thalamus_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.42678
GSE217405_3_v_2_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RCOR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19T-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE242049_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MYC_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K76487707	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.41946
CALCA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00372206
POLR2A_K562_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EPLC-272H	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.64695
lateral portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.09946
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-5442-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NCI-H1651	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.24586
H3K4me1_CD8 Memory Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6825-01A-21R-1915-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
intermediate stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.10783
H3K4me3_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE198165,GSE198166_6_v_2_zfp266_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of protein targeting to membrane	GO Biological Process Annotations 2023	1.0	null
HMMR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00598191
Prostate gland	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.318
GTEX-P44H-0011-R8A-SM-2XCEL	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54192
GTEX-PLZ6-0006-SM-33HBZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.97179
POLR2AphosphoS2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of biological process	GO Biological Process Annotations 2015	1.0	null
GSE48812_2_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
USF1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Fasudil_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0137798
K562_RG108_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.017109
ZEB1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_iPS DF 6.9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE146962_0_v_1_glucosamine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE44157,GSE44163_3_v_0_nr6a1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE155031_5_v_0_dextran_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE122215,GSE122217_5_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE200839,GSE233826_2_v_4_tnrc18_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE125014_6_v_2_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
TGIF2LY	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6892
H3K4me1_embryonic fibroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE228430_1_v_3_fabp5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A	ENCODE Transcription Factor Targets	1.0	null
EGR1_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154197_1_v_2_ints13_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE212312_2_v_3_fbxw7_human	RummaGEO Gene Perturbation Signatures	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-33-4587-01A-11R-2125-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-WYJK-0005-SM-3NMA1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.970185
BRD-A55594068_VINBLASTINE SULFATE_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
iodoquinol	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62007
gossypol-2202	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE161864,GSE161866_0_v_2_ror2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE221327_6_v_0_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K55722623_-666_MCF7_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K94993773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2299
LRRC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.47499
WAOSEL	DepMap CRISPR Gene Dependency	1.0	2.15709
gracile nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.06203
molecular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.35664
USF2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-3.89243
A549_Decitabine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0144271
NUFIP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.15062
GSE182179_2_v_1_kdsr_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K15791587_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE234340_9_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Dhori Virus_12Hour_20090954_GSE17400	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.49023
F0447-0125-6424	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
19621087-Table1d	GeneSigDB Published Gene Signatures	1.0	null
GSE96544_1_v_0_mebendazole_human	RummaGEO Drug Perturbation Signatures	-1.0	null
genistein-2695	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE184902_4_v_1_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PPP3CA	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.59742
MOLM-13	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CCNT2	ENCODE Transcription Factor Targets	1.0	null
medial trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.29863
Amylin receptor complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.815
GSE242199_6_v_3_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE78199_2_v_1_tamoxifen_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HUO9	DepMap CRISPR Gene Dependency	1.0	2.08213
POU5F1	ChEA Transcription Factor Targets	1.0	null
H4K20me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
wt1_00000000_mouse_embryonic_fibroblast_mef_lof_mouse_gpl1261_gse15325	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.018933
GSE175883_0_v_1_dis3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Dorsal peduncular area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53077
PRKAA2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00435626
WDR37	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00482913
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.937523
BRD-K35326556	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81109
PMC6744561-41467_2019_12125_MOESM7_ESM.xlsx-Normal_309_TCF7_rep1_sorted_pea-Gene_Name_TCF7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE180200,GSE180201_5_v_6_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF143_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
lateral subdivision of BNST	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.928647
regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
GTEX-O5YT-1326-SM-3MJGR	GTEx Tissue Sample Gene Expression Profiles	1.0	1.7964
GSE157050,GSE157051_2_v_3_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE196259_2_v_0_gcm1_human	RummaGEO Gene Perturbation Signatures	1.0	null
substantia nigra, pars reticulata, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.91982
H4K8ac_IMR90	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
TFAP2C_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAPT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00572602
GSE199538,GSE199539_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1599	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824203
GSE203329_0_v_3_mettl5_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7177-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
KLF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.39531
Perturb_17648_KO_CEP83_SRP379856	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-3.56831
hsa-miR-548j	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
H3K4me3_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XQ3S-0006-SM-4BOQ4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.65444
hsa-miR-764	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
RS11846	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.998155
CTCF_GM12868_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K86824573	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23947
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824203
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.887236
regulation of protein targeting to membrane	GO Biological Process Annotations 2025	1.0	null
POLR2A_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_13_v_11_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_liver_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE213588_8_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-SIU7-0006-SM-2XCE6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46576
GTEX-N7MS-1626-SM-3LK5F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.946982
Rectum adenocarcinoma_READ_TCGA-EI-7002-01A-11R-1928-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE102132_2_v_1_irf3_human	RummaGEO Gene Perturbation Signatures	1.0	null
Copula pyramidis, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05546
GTEX-U3ZN-0826-SM-4DXSZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0365
PAX5	ENCODE Transcription Factor Targets	1.0	null
striatum_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.08784
regulation of cellular component movement	GO Biological Process Annotations 2015	1.0	null
H3K4me3_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE60837_0_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-TKQ2-0226-SM-4DM6V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.44819
GTEX-QDT8-0011-R10A-SM-32PKG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51764
BRD-A44448661_PENTOBARBITAL_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K59099886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.52297
Perturb_1433_KO_Kmt2c_SRP283007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.6672
PGAM5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0174
GTEX-Q2AI-0226-SM-48U1D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47934
CTCF_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bone marrow	HPA Tissue Gene Expression Profiles	-1.0	-2.02849
C32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	3.18949
alitretinoin_homo sapiens_gpl6480_gse43090	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SMC3_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K31820800	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37151
MCF7_Tofacitinib_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0112264
MZ in orbital frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.56162
LS513	DepMap CRISPR Gene Dependency	1.0	2.39083
Pheochromocytoma and Paraganglioma_PCPG_TCGA-RX-A8JQ-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_cardiac fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE71100_0_v_1_lin28b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.19213
GTEX-XLM4-3126-SM-4AT6M	GTEx Tissue Sample Gene Expression Profiles	1.0	0.958498
BRD-K02241673	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.91974
superficial stratum of r6BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20982
CTCF_HGPS cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178340_5_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_7218_KD_NOL9_SRP321650	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K4me1_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RXRA_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-134-VI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.67374
BRD-K67860401_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC11743796-41420_2025_2295_MOESM5_ESM.xlsx-aged_LPS_BV-2_vs_human_downreg-human_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GLUD2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0050825
BRD-K68407802_KIN001-055_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
r1 roof plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.15423
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40359
GSE169571_0_v_2_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4436b-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.474009
GSE152050,GSE152052_1_v_0_arid1a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NR2F2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CYP17A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00596238
ROBO3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.90667
bonemarrow_6c	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.68008
GSE217115_2_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Organ system cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.077
Brain Lower Grade Glioma_LGG_TCGA-HW-8322-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K27me3_G1E-ER4_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_AR-42_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0146136
AG-012559-6920	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7897-01A-21R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE219195_0_v_5_rbm12_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178340_1_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K15201964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19828
ROS50	DepMap CRISPR Gene Dependency	1.0	3.21015
BRD-K55946794	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19358
GSE119498_2_v_4_setd5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H2AC12	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00519132
H3K4me3_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QCQG-0006-SM-2S1OW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43484
BRD-K69520171	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.2766
GSE119498_0_v_7_setd5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
1,5-isoquinolinediol-543	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE95077_1_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
IRAK4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0058154
GSE178340_1_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PVOW-0011-R3A-SM-32PKX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.39833
K562_Entinostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0150148
KDM4A	ENCODE Transcription Factor Targets	1.0	null
GTEX-XUW1-0008-SM-4BOQH	GTEx Tissue Sample Gene Expression Profiles	1.0	0.8589
HDAC2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of intracellular protein transport	GO Biological Process Annotations 2023	1.0	null
CTCF_epithelial cell of proximal tubule_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
BRD-K33956247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.51692
GSE142210_9_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE225901_2_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE244710_3_v_0_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
HSC4	CCLE Cell Line Gene CNV Profiles	-1.0	-1.55015
BRD-K84821804	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1404
H3K27ac_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE202284,GSE202289_12_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228263_0_v_1_elesclomol_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAD21_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE245407,GSE245412_0_v_1_smurf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE120612_6_v_3_etoposide_human	RummaGEO Drug Perturbation Signatures	1.0	null
Medial amygdalar nucleus, posteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12266
cellular_component	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
PMC10153265-media-3.xlsx-BENPORATH_SOX2_TARGETS_v2023_1-STANDARD_NAME_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE131649_6_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-2cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
TOM1L1	Pathway Commons Protein-Protein Interactions	1.0	null
HNF4A-19822575-HepG2-human	ChEA Transcription Factor Binding Site Profiles	1.0	null
SK-CO-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.11468
GSE182835,GSE182836_0_v_1_siah2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_astrocyte of the spinal cord_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZAP70	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0058657
16715129-SuppTable4	GeneSigDB Published Gene Signatures	1.0	null
YY1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE88819_11_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
XIAP	Pathway Commons Protein-Protein Interactions	1.0	null
endopiriform nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.05193
GSE202744_1_v_3_toyocamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Carbamazepin-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
NHERF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10774
LIVF001-029	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.22766
MFM-223	COSMIC Cell Line Gene Mutation Profiles	1.0	null
Gustatory areas, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.32265
diflorasone-2142	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZNF418	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.1832
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4781-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5149-01A-01R-1514-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
plasma membrane	GO Cellular Component Annotations 2015	1.0	null
GSE133087_1_v_0_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_7804_KO_Ythdc1_SRP065329	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
PMC10153265-media-3.xlsx-BENPORATH_NANOG_TARGETS_v2023_1-STANDARD_NAME_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-VUSH-0005-SM-3NB2H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.30694
MAFK_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149880_2_v_1_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_PHA-680632_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0130083
FOXP2_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_mammary epithelial cell_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC11310865-jcav15p5118s1.pdf-15-DMTF1_DMTF1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S3XE-0126-SM-4AD4R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.99672
PMC6347712-pnas.1812449116.sd05.xlsx-iPSC_IRF7_48h_RNAExpress-Gene_IRF7	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K77700305	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37396
SNU1033	CCLE Cell Line Gene CNV Profiles	1.0	2.78674
Perturb_5152_KD_Ell3_SRP013333	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
H3K4me3_Caco-2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE162739_2_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216352,GSE216354_1_v_0_keap1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-PWO3-0011-R8A-SM-2I5GD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16202
GTEX-T5JW-1326-SM-4DM5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.934416
negative regulation of cell motility	GO Biological Process Annotations 2015	1.0	null
H3K23me2_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-OOBK-1626-SM-2HMKG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876575
Amylin receptor complex 1	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.904
GSE87412,GSE92423_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K34541722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.19193
GSE191015_0_v_2_gsdmb_human	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT3	JASPAR Predicted Transcription Factor Targets	1.0	null
NCIH1581	DepMap CRISPR Gene Dependency	1.0	2.8833
GSE189609_1_v_0_hax1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE175787_4_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of the Fc	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.03695
GSE201309_4_v_3_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
negative regulation of cell migration	GO Biological Process Annotations 2023	1.0	null
VIIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.98948
CTCF_astrocyte of the cerebellum_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JW-0005-SM-3GADE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.89209
GSE128634,GSE128636_2_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-WZTO-0011-R5B-SM-3NMC5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.51222
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66821
Perturb_1707_KD_Rad21_SRP132608	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	15.8869
RAD21_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8305C_THYROID	CCLE Cell Line Proteomics	1.0	4.29684
GTEX-N7MS-0011-R3a-SM-33HC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35398
GSE77108_3_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
TAF1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89018_6_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SOX17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00514933
mantle zone of CbH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33174
GSE151612_4_v_7_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149123,GSE149128_3_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE142210_2_v_1_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me1_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-XLM4-0011-R3B-SM-4AT6E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10765
BRD-K20039572	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17948
BRD-K92722247	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.65112
CYLD	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_3420_KO_USP7_SRP330182	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
TRIM28_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE225735_0_v_4_aldosterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_myotube_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OIZG-0005-SM-2HMJC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08695
GTEX-R55E-0011-R11A-SM-2TC6I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869669
MCF7_Tubastatin A HCl_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0191239
regulation of transmembrane transporter activity	GO Biological Process Annotations 2015	1.0	null
BRD-K32821942_azathioprine_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE157594_5_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2A_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K54997624_BYL719_HT29_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_fibroblast of pulmonary artery_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_7_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
RAD21_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
vitamin c_homo sapiens_gpl570_gds3635	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63053
TFAP2A	JASPAR Predicted Transcription Factor Targets	1.0	null
STAT5A	ENCODE Transcription Factor Targets	1.0	null
3050_FDPS_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.55737
EZH2	ENCODE Transcription Factor Targets	1.0	null
Primary somatosensory area, unassigned, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.07214
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A1OB-01A-11R-A14Y-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
cerebellar cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.874652
A549_Ki8751_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.014785
EZH2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.41073
GTEX-U8XE-0005-SM-3DB8I	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02371
BRD-K11566982	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61671
BRD-U70626184_BI-2536_MCF7_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE142210_2_v_8_panobinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
HT1080	DepMap CRISPR Gene Dependency	1.0	2.70826
MAFK_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TACR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00548383
LIVF001-017	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.50531
NEUROD1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3961
STOCK1N-35215-6422	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MXI1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHL-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.16726
7141_RBBP5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.637708
CHML	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.26907
POLR2A_GM12892_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-1275	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Uterine Carcinosarcoma_UCS_TCGA-N6-A4VF-01A-31R-A28V-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BACH1	ENCODE Transcription Factor Targets	1.0	null
GTEX-S4UY-0006-SM-3K2A7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.959794
GSE248858_1_v_3_tcpobop_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
COPI-coated vesicle	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.868
Fibroblast_Lung_Mouse	CellMarker Gene-Cell Type Associations	1.0	null
GSE182680,GSE182683_0_v_13_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XOTO-0008-SM-4GICE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02616
APOBEC2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.52489
KE39	CCLE Cell Line Gene CNV Profiles	1.0	1.34078
H3K4me3_retinal pigment epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K76215709	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.75907
GSE147876,GSE147877_2_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r6 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31128
GSE93309_1_v_0_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2AphosphoS5_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD2	ENCODE Transcription Factor Targets	1.0	null
BRD-K64763803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03068
GSE125219,GSE125221_4_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-Q2AG-0011-R7A-SM-2HMJP	GTEx Tissue Sample Gene Expression Profiles	1.0	0.878387
RXRA_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE131649_6_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
rhombomere 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04844
CTCF_WERI-Rb-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE216043_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE218580_1_v_2_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
C2BBE1	DepMap CRISPR Gene Dependency	1.0	4.74492
K562_AG-14361_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0156094
JUND_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYBL2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MBD3-35695185-NICBASALROOTGANGLIA-MOUSE-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
E2F6_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
all	GWASdb SNP-Phenotype Associations	1.0	0.028243
primary motor cortex (area M1, area 4)_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.935924
GSE114232_10_v_11_mavs_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE211128_3_v_5_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE82104,GSE82299_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
C32	COSMIC Cell Line Gene CNV Profiles	1.0	2.09117
(-)-MK-801-3081	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TE9	CCLE Cell Line Gene CNV Profiles	-1.0	-2.57347
RAD21_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE92457_9_v_12_ethanol_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-NPJ8-0011-R8a-SM-2HMLG	GTEx Tissue Sample Gene Expression Profiles	1.0	2.08402
MAPK3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00429854
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.16955
H3K4me3_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
rostral putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.02545
MID2	Pathway Commons Protein-Protein Interactions	1.0	null
GSE95077_5_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K07313741	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.00499
GSE116930,GSE116935_3_v_6_hes7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
STAT5A_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202284,GSE202289_5_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE102505_5_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
paraventricular nuclei, right of thalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.847426
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HE-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE130437_0_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MFM-223	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
G111	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18504
CBX3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZBTB7A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE100316_3_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PMC4944136-srep28995-s2.xls-DUXA-gene_DUXA	Rummagene Transcription Factor Associations 2026	1.0	null
GSE166914_1_v_0_abemaciclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NCIH1793_LUNG	CCLE Cell Line Proteomics	1.0	2.49584
TAF1_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SUIT-2	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.44487
PMC12663032-mmc7.xlsx-Supp_T6-Supplemental_Table_6_Dual_treated_vs_vehicle_treated_MSC_top_DEGs_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_6307_KD_NR2F1AS1_SRP335917	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	2.32397
A549_Danusertib_100nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131948
HNF4A	ENCODE Transcription Factor Targets	1.0	null
GTEX-PVOW-2726-SM-48TCA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.886835
H3K4me3_B cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC7892341-41388_2020_1606_MOESM3_ESM.xlsx-Tables_S4-RNA-seq_LetR_only_AIB1_differentially_expressed_genes_not_present_in_MCF7_cells_Related_to_Figure_1_NCOA3	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_14447_KO_Jmjd3_SRP356900	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.44057
FOXA1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE178113,GSE178116_0_v_1_atrx_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Simple lobule, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28895
GSE115542_2_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBL1XR1	ENCODE Transcription Factor Targets	1.0	null
MM.1S	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.32329
GSE233183,GSE233187_3_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Sox7	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	20.3032
PRR19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.45287
u698	HPA Cell Line Gene Expression Profiles	-1.0	-1.42113
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_CoCl2-HIF2_-related_miRNA_targets_expression_during_hypoxia_based_on_micorarray_FC_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
MPG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.01374
H3K4me1_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE136894_1_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE133691_2_v_0_lgr5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K83508485_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Magnocellular reticular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05995
BRD-K14920963_ERYTHROSINE SODIUM_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ZBTB7A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0005-SM-2TF4Z	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.994714
FOXA2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_K562_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
8-M-PDOT	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35861
BRD-K13572796	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43647
GSE165682_0_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
JIMT1	CCLE Cell Line Gene CNV Profiles	1.0	1.34955
H3K4me3_fibroblast of mammary gland_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE228181_2_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
6442_PLEKHG2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.566857
GSE127790_4_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZBTB26	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.50547
GTEX-QEG5-0426-SM-2I5GJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.96164
H3K4me3_thymus_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
layer II of area 35c	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.04726
H3K4me3_megakaryocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
YY1_K562_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.132
SMC3_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-0008-SM-4AT3Y	GTEx Tissue Sample Gene Expression Profiles	1.0	0.830386
GSE173810_0_v_1_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Disulfiram_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0212124
MAX_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226983_1_v_0_ddx5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TGIF2LX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.1945
mRNA_ASCL2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
SUZ12_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE74251_2_v_1_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE135350_3_v_5_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
EP300_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCC1395	COSMIC Cell Line Gene CNV Profiles	1.0	2.09117
H3K4me1_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
r4 part of medial pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.26012
GSE198165,GSE198166_9_v_1_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
hsa-miR-374c	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
positive regulation of ion transmembrane transporter activity	GO Biological Process Annotations 2023	1.0	null
Rarb	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	50.9137
EZH2_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of anion channel activity	GO Biological Process Annotations 2023	1.0	null
Perturb_1687_KO_Kmt2c_SRP283007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	6.06719
STAT5A-24692510-EPITHELIUM-MOUSE-MAMMARY	ChEA Transcription Factor Targets 2022	1.0	null
MORN4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.05491
VZ in septal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.64659
FOXM1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r7BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.60465
GSE182680,GSE182683_5_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
16707422-tableS1a	GeneSigDB Published Gene Signatures	1.0	null
BRD-K76065617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70683
hsa-miR-605	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
GTEX-TKQ2-0006-SM-33HBH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34987
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4741-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
CTCF_MCF-7_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
bonemarrow_5a	HPA Tissue Sample Gene Expression Profiles	-1.0	-2.84534
16151515-TableS4	GeneSigDB Published Gene Signatures	1.0	null
GSE131588,GSE131690_1_v_0_setd2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178340_5_v_4_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-UTHO-0011-R11A-SM-3GIJE	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0244
posteromedial visual area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.58546
RUNX3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE111660_4_v_3_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
lateral septal nucleus, intermediate part, periventricular	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20987
TFAP2A-35110662-HEPM-HUMAN-EMBRYO	ChEA Transcription Factor Targets 2022	1.0	null
lateral trapezoid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.54427
CYP1A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00643171
putamen, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.828407
EP300_GM12878_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FU97	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.37946
GSE157555,GSE157556_3_v_7_foxa2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM12875_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
PMC9314667-Table_1.xlsx-Regulons-FOSL2_FOSL2	Rummagene Transcription Factor Associations 2026	1.0	null
CP in caudal hippocampus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.41561
BRD-A48228341	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.20586
GSE127790_5_v_2_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
C3orf38	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47328
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_2_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
CAMA1	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.935944
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-5988-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE164874_5_v_0_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE168807_0_v_8_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-S7SE-0011-R7A-SM-2XCDI	GTEx Tissue Sample Gene Expression Profiles	1.0	1.71417
Bed nuclei of the stria terminalis, anterior division, oval nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35959
Cerebellum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.17225
Brain Lower Grade Glioma_LGG_TCGA-DU-8166-01A-11R-2256-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XLM4-0008-SM-4AT4W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.875131
mRNA_CDX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-UPJH-0006-SM-3GACW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16812
TEAD4_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XX-0005-SM-3NMCS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21818
ANKRD55	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00561339
BRD-K05610303	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.26648
A549_Tanespimycin_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0132991
GTEX-OHPM-1626-SM-2HMK4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.833068
GTEX-WZTO-0006-SM-3NM9T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08995
hsa-miR-9	TargetScan Predicted Conserved microRNA Targets	1.0	0.187098
POLR2A_HepG2_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PML_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1792	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.31568
BRD-K27058632	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05289
GSE48812_4_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
GPATCH3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16451
GSE220914_2_v_0_zdhhc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
layer 6a of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91024
PCI30	DepMap CRISPR Gene Dependency	1.0	2.06439
GSE195559_2_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE119978,GSE180930_6_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE193993_5_v_2_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_K562_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4477a	TargetScan Predicted Conserved microRNA Targets	1.0	0.348832
P2RX7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00423519
SW1990	DepMap CRISPR Gene Dependency	1.0	2.32135
Cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.086
medial (fastigial) cerebellar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01524
GTEX-SSA3-0002-SM-3P61R	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.848305
GSE176008_0_v_1_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102505_6_v_0_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XLM4-0011-R10A-SM-4AT5P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16334
GSE118766_2_v_0_ifng_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27ac_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE136894_1_v_0_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE145639_1_v_2_adar_human	RummaGEO Gene Perturbation Signatures	1.0	null
REST_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133087_3_v_2_metformin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K95033255	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31159
GTEX-WVLH-0011-R2A-SM-3MJFJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03954
PTPA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00631108
EGR1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_kidney_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_4359_KD_TARDBP_SRP166282	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.02239
GTEX-X4EP-0005-SM-3P5ZE	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74133
19841744-TableS5	GeneSigDB Published Gene Signatures	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A73C-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RL7	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.40516
NRF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SYK_knockdown_191_GSE54065	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.46499
ZC3H11A	ENCODE Transcription Factor Targets	1.0	null
TRIM28_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7399-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
G-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75712
IDRA-21	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32632
K562_Raltitrexed_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170275
H3K27ac_brain_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
REST_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial amygdala, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1853
H4K20me1_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Perturb_13274_KO_Zbtb24_SRP198760	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	13.7025
CTCF_A549_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-2526-SM-2XCF7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16565
OPRK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00628191
sirolimus_homo sapiens_gpl96_gds2494	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
regulation of ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
GSE226408_2_v_3_inpp4b_human	RummaGEO Gene Perturbation Signatures	1.0	null
mianserin-1385	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MRPS16	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06799
EP300_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K15380626	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03016
EFEMP2	Pathway Commons Protein-Protein Interactions	1.0	null
IGR1	CCLE Cell Line Gene CNV Profiles	1.0	2.03128
GSE88819_6_v_2_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE201309_4_v_7_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
KAT2B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KDM4A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZNF384_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pontine nuclei, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03482
GSE126127_0_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153867_6_v_8_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9327205-11658_2022_358_MOESM7_ESM.xlsx-K562-BP1-Symbol_1_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
GSE230744,GSE237803_0_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
supraoptic nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.26701
GSE142430_3_v_1_prmt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE88819_11_v_4_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130690,GSE130692_1_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2964-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
fastigial nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.4731
ELK1	ENCODE Transcription Factor Targets	1.0	null
CTCF_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
R3HDM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00963359
TGBC11TKB	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-WRHK-0005-SM-3MJF5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.43405
GSE198165,GSE198166_9_v_3_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NDUFS7	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.15958
GSE147056_0_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K06886551	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05589
8332_SPC25_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.527599
GSE145323,GSE145324_1_v_0_rfx3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of anion channel activity	GO Biological Process Annotations 2025	1.0	null
721_B_lymphoblasts	BioGPS Human Cell Type and Tissue Gene Expression Profiles	-1.0	-1.71586
GTEX-WWYW-0011-R6A-SM-3NB3G	GTEx Tissue Sample Gene Expression Profiles	1.0	1.96713
BRD-A49544621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.95412
H3K27ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R3RS-0005-SM-3GAEH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1442
BRD-K93990956	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.5786
POLR2A_lung_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
localization	GO Biological Process Annotations 2015	1.0	null
MAP2K6	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00571566
GSE158320,GSE183351_0_v_3_lin28b_human	RummaGEO Gene Perturbation Signatures	1.0	null
H2AFZ_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
physostigmine-1776	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-V955-0005-SM-3P5ZC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.69631
K562_AG-14361_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0152227
WARS1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.17588
cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33059
hsa-miR-4688	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
Lung adenocarcinoma_LUAD_TCGA-50-6592-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LK-2	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE153871_0_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Pyramus (VIII), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32604
WRNIP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE209582_1_v_2_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K70543679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30484
BRD-K51608228	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01017
NEK9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0831
VIIIA, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26146
GSE153137,GSE153140_2_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AXL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00705723
hsa-miR-4762-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.175726
Retrosplenial area, lateral agranular part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.79649
KG1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.59654
GTEX-TMMY-1326-SM-4DXU9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.826391
MCF7_Altretamine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0148791
A549_SRT2104_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0115439
Bladder Urothelial Carcinoma_BLCA_TCGA-HQ-A2OF-01A-11R-A26T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-A63704386	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02824
H3K27ac_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE158834_2_v_4_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
K562_Ofloxacin_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0175648
GSE94849_6_v_4_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WZTO-0011-R3B-SM-3NMC6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22547
arcuate nucleus of hypothalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.33797
tamoxifen_homo sapiens_gpl3921_gse33366	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE168596_1_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
MAP3K5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0044666
GSE149880_2_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
OBSCN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.2021
H3K27me3_G1E_mm9_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Duodenum Mucosa	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE210580_5_v_7_rag2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AOB, outer plexiform layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27818
HNF4A	ChEA Transcription Factor Targets	1.0	null
GSE217776,GSE217829_1_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
skeletalmuscle_b	HPA Tissue Sample Gene Expression Profiles	-1.0	-0.847028
CRCGN015_HEPG2_48H:G13	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.9849
BRD-K90797575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.58493
BRD-K77324165	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37448
GTEX-T6MO-0006-SM-32QOU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.5734
regulation of ion transport	GO Biological Process Annotations 2015	1.0	null
CTCF_GM12872_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12105018_5841365_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.163
UFD1L	Pathway Commons Protein-Protein Interactions	1.0	null
RPE1SS119	DepMap CRISPR Gene Dependency	1.0	2.31215
GTEX-QVUS-0011-R8A-SM-3GAD7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82166
MCF7_PCI-34051_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0129103
r6 part of ventral gigangocellular reticular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06539
BRD-K66222602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27189
PANX1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00700511
SMC3_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K08881846	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.23465
Simple lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.31801
Perturb_3924_KD_VPS37B/VPS37C_SRP266781	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.7935
H3K9ac_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAFF_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE188870,GSE188871_0_v_5_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
amygdalo-striatal transition	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.31347
CTCF_endothelial cell of umbilical vein_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12865_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R3A-SM-3TW8E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05105
Pyramus (VIII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.32719
hsa-miR-4490	TargetScan Predicted Conserved microRNA Targets	1.0	0.997906
USP13	Pathway Commons Protein-Protein Interactions	1.0	null
MDA MB435	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.83597
GSE160817_4_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE197850_4_v_3_glucagon_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE158632_3_v_4_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE218378_1_v_0_pbx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_fibroblast of foreskin _hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-NL4W-0011-R6a-SM-2I3GA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19112
3871_HNRNPL_P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.736374
cellular_component	LOCATE Predicted Protein Localization Annotations	1.0	null
4716_LUC7L3_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.673593
PMC6187090-mmc1.xlsx-TP53_positive-Symbol_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
TAF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-1726-SM-46MVO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.942037
CAMK1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0056818
4147_INTS2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.535724
Malignant Neoplasm	DisGeNET Gene-Disease Associations	1.0	null
SNU840	DepMap CRISPR Gene Dependency	1.0	2.00512
BRD-K17610834	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20148
periventricular stratum of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22695
SQ1_LUNG	CCLE Cell Line Proteomics	1.0	2.08079
BRD-K01067435	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.06877
dorsolateral prefrontal cortex_26 pcw_F_12949	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.883848
CTCF_GM12871_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.82361
ICAM4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.83792
BRD-K62358193	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53119
GSE216413_1_v_0_gata3_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE221577_3_v_0_pik3r1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SP1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF263_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QVJO-0011-R6A-SM-2S1QN	GTEx Tissue Sample Gene Expression Profiles	1.0	3.06157
GSE95077_1_v_3_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE149903_4_v_2_myd88_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
REST_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K9ac_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
periventricular stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13792
GSE174735_1_v_3_il22_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTF2F1	ENCODE Transcription Factor Targets	1.0	null
channelassociated	GeneRIF Biological Term Annotations	1.0	null
GTEX-OXRK-0126-SM-3NB1E	GTEx Tissue Sample Gene Expression Profiles	1.0	1.6174
PMC5263239-mmc2.xls-SEM_-_MLL-AF4-Non-spreading_targets_gene_names_2497_unique_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA1_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE229344_1_v_0_cyb5r3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6357748-aau9223_Table_S1.xlsx-CD4_T_-_LPS-Unnamed_0_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A78360835_cercosporin_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
15260889-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
K562_Carmofur_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143446
fenspiride-1422	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE184133,GSE184137_2_v_5_esrrb_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tetramisole-2489	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
cell part	LOCATE Predicted Protein Localization Annotations	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Dextrometh-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
SNAI2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.19401
GTEX-PWO3-0005-SM-2I5FS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25995
posterior (caudal) superior temporal cortex (area 22c)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.09816
BRD-K70875838	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07382
CHD2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548ab	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
GSE157296,GSE157298_4_v_5_kbtbd4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE214596,GSE214598_1_v_2_rosiglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
EBF1	ENCODE Transcription Factor Targets	1.0	null
BRD-K23957028	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58886
PHF20L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.22588
H3K4me3_cardiac mesoderm_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H510A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.941778
mRNA_JARID2_20075857	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-QVJO-1426-SM-2S1QY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.925881
NCIH2004RT	DepMap CRISPR Gene Dependency	1.0	3.38804
PB-09-OE00_1uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.219331
HOXB6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.1901
GTEX-WHSE-0011-R5A-SM-3P5ZO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78424
BRD-K28803288	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.03742
CA3 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.45071
TAF1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X4XY-0006-SM-46MV2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06211
positive regulation of anion channel activity	GO Biological Process Annotations 2015	1.0	null
K562_Disulfiram_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0165616
Skin Cutaneous Melanoma_SKCM_TCGA-ER-A19D-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K45959036	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12047
NFYA_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WI38_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
L-363	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.12144
KDM5B_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WZTO-0011-R10B-SM-4E3KB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15619
BRD-K20072174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34781
GSE218060_7_v_3_decitabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
TRIM28_U2OS_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WFG7-0001-SM-3P61S	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.836178
H3K4me3_SK-N-SH_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K33998683	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.71377
GSE48812_0_v_6_sulforaphane_human	RummaGEO Drug Perturbation Signatures	1.0	null
IPMK	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00527068
CTCF_MCF-7_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PX3G-0926-SM-48U12	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.853245
JVM3	DepMap CRISPR Gene Dependency	1.0	6.48734
Parietal lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.775
GSE193993_0_v_6_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7021759-41467_2020_14682_MOESM10_ESM.xlsx-downregulated_genes-Table_S7_Dowregulated_genes_in_SKNMM_and_U2OS_cells_with_MYCN_induction_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE132948,GSE132949_4_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
NOL11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.01818
YY1_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T5JC-0011-R7A-SM-32PME	GTEx Tissue Sample Gene Expression Profiles	1.0	1.70124
GSE242199_6_v_7_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201239_0_v_7_fmr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GABPA_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HCT116	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.34298
GSE124920_1_v_2_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE216043_10_v_9_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE88819_7_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K25805580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.5831
AOB, glomerular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41848
CTCF_keratinocyte_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_CD8 Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Piriform-amygdalar area, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.00143
GSE238116_1_v_0_egr1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T5JC-0011-R11A-SM-32PMB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.934605
GSE188870,GSE188871_1_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196110_1_v_2_ndrg3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE176093_2_v_3_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.866056
H3K4me3_mammary epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A5GR-06A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K73637411	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.23833
striatum_21 yrs_F_13057	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.72313
GSE216043_3_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
hypoglossal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03298
BHLHE40_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN2_n_EN2	Rummagene Transcription Factor Associations 2026	1.0	null
GSE147366_1_v_0_med13_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Nodulus (X), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12459
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A1Q1-06A-21R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-PSDG-0005-SM-3GADC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02129
GSE111660_2_v_5_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
HT-55	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PMC8650352-JCB_202012097_DataS1.xlsx-VHL_KD_proteinGroups-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
daudi	HPA Cell Line Gene Expression Profiles	-1.0	-1.18352
BRD-A17428743_BW 723C86 hydrochloride_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K64763786	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.05041
V, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.14608
GSE158197_6_v_10_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
MTA3	ENCODE Transcription Factor Targets	1.0	null
SIN3A_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC6814198-NIHMS1538462-supplement-2.xlsx-Transitory_415genes-SNAI2_SNAI2	Rummagene Transcription Factor Associations 2026	1.0	null
OCIM2	DepMap CRISPR Gene Dependency	1.0	5.55873
levodopa-1472	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MAZ_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
S-layer	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.501
GSE231648_4_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XMK1-0005-SM-4B665	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00338
SUDHL10	DepMap CRISPR Gene Dependency	1.0	4.83944
ventrolateral prefrontal cortex_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.40535
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.44456
CRCGN015_HEPG2_48H:C23	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-2.85718
Agranular insular area, ventral part, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.29545
K562_BMS-265246_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136002
BRD-K80622725_STK397047_VCAP_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
brain	GTEx Tissue Gene Expression Profiles	1.0	1.1027
GSE160083,GSE160084_1_v_3_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE133691_1_v_3_lgr5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
ZNF143_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
globus pallidus, internal segment, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.923259
RLIM	Pathway Commons Protein-Protein Interactions	1.0	null
H3K4me1_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RPMI 8226	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.988589
SK-N-FI	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.72104
GSE238018_3_v_2_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
MYC_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE238018_3_v_4_mxra8_human	RummaGEO Gene Perturbation Signatures	1.0	null
abducens nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.06074
troglitazone-1070	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-548ak	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
ChIP_TCF3_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Hindbrain	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.236
Anteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1152
GSE157777_2_v_3_foxa3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A20697603_598226_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE242199_2_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_TGX-221_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0137769
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5264-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
K562_Resveratrol_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0165497
SW 1116	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.23531
GTEX-XMD1-0006-SM-4AT4Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.18281
H3K4me3_endothelial cell of umbilical vein_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K9ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-RM2N-0326-SM-48FD8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843643
superficial stratum of r7BL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03439
Caudatenucleus	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.16013
PMC9336541-Table_3.XLSX-C-vs-H6-L_filter_annot-Unnamed_18_HMX1	Rummagene Transcription Factor Associations 2026	1.0	null
amygdala	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.32042
H3K4me3_retinal pigment epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE69244_1_v_0_j147_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Teriflunomide-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
UHO1	DepMap CRISPR Gene Dependency	1.0	3.5962
SIN3A_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE218060_7_v_0_decitabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD21_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
etoposide_homo sapiens_gpl10558_gse33990	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE152441,GSE152442_7_v_4_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
TNKS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0061125
SOX2	ChEA Transcription Factor Targets	1.0	null
PMC11058205-42003_2024_6202_MOESM5_ESM.xlsx-Data2c_CEBPA_ChIP-Unnamed_9_CEBPA	Rummagene Transcription Factor Associations 2026	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.15767
furegrelate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.63956
olfactorybulb	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.986061
GSE215086_3_v_0_batf_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-HIF1_HIF2_miRNA_targets_CoCl2-Unnamed_12_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
18757322-TableS1	GeneSigDB Published Gene Signatures	1.0	null
GSE87412,GSE92423_2_v_1_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
dorsorostral division of MFC (area 32)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32506
Perturb_1658_KO_Gpr174_SRP365825	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-8.94393
Agranular insular area, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02042
huh-7	BioGPS Cell Line Gene Expression Profiles	1.0	1.31135
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A3LQ-01A-21R-A21T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158431_2_v_6_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Costunolide_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167557
sp3_17923686_e12dot5_heart_lof_mouse_gpl1261_gds3058	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.064343
vitamin c_mus musculus_gpl1261_gse37676	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE134375_0_v_2_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_FLLL32_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0166678
RGS19	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.36681
Lung squamous cell carcinoma_LUSC_TCGA-33-6737-11A-01R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210101,GSE210114_6_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF75A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.4375
PMC4729482-pone.0146505.s001.xlsx-Sheet1-ccRCC_positively_correlated_with_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
central nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
CTCF_fibroblast of lung_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
10623_ZNF774_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.621415
GTEX-R55F-0011-R6A-SM-2TF4L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76022
Rectal Mucosa Donor 31	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.71698
GSE244710_1_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R53T-0226-SM-48FEH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.24572
hsa-miR-3922-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
GTEX-XGQ4-0005-SM-4AT5U	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.67958
GSE226249_0_v_1_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SIN3A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
fulvestrant-6918	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-TMZS-0326-SM-3DB9P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.911781
Paramedian lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.28109
Perturb_17186_OE_ESR1_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
t60-adrenal_consensus	MoTrPAC Rat Endurance Exercise Training	1.0	2.6713
superficial stratum of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4045
GSE224547_1_v_0_cftr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
captopril-1907	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE199255,GSE199356_6_v_5_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE118548_1_v_0_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC1806	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-2.29343
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A3A2-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFX5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE238005_0_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S4Q7-0226-SM-4AD5O	GTEx Tissue Sample Gene Expression Profiles	1.0	1.47926
BRD-A31946439_NCGC00241077-01_A549_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
USF1_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0011-R11A-SM-32PKD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.966293
IRF1	ENCODE Transcription Factor Targets	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7382-01A-11R-2132-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Gastrointestinal stromal tumor_Gastric Tissue_GSE15966	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.45682
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	3.4231
BRD-K09777330	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.29319
Extrachromosomal circular DNA	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.529
Darolutamide_AN3 CA	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0105927
GSE95077_5_v_4_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_IOX2_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0185555
SARS-dORF6_36Hour_23935999_GSE47962	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.4076
PMC9377669-tx1c00392_si_002.xlsx-DPH-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
ion channel binding	GO Molecular Function Annotations 2015	1.0	null
GSE221327_10_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-11_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
FOXA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS2-20176728-TROPHOBLAST STEM CELLS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
451Lu	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.53161
K562_Alisertib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161574
HNF4G_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_fibroblast of foreskin _hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-S3XE-0006-SM-3K2AA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.21777
TEF-1	MotifMap Predicted Transcription Factor Targets	1.0	null
VZ in subcallosal region	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.864901
H3K4me3_fibroblast of lung_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GSE122378_0_v_1_carmil3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
pallidal amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25241
BRD-K68853384	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28523
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-3_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
CEP250	Pathway Commons Protein-Protein Interactions	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.09102
GTF2B	ENCODE Transcription Factor Targets	1.0	null
GSE151612_0_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
18787207-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GTEX-UTHO-3126-SM-3P5ZB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.89924
PMC3607232-mmc1.xls-RS411_SEM_common_AF4_MLLN_K79Me-MLL_AF4_H3K79me3_SEM_n_2490_KMT2A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE135350_3_v_0_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-O5YW-0006-SM-3LK6E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.38759
BRD-K62312047	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.20925
GSE193993_1_v_3_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H4K20me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
mantle zone of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24382
STAT3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.4913
GSE235066_4_v_0_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posteromedial visual area, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1853
KYSE450_OESOPHAGUS	CCLE Cell Line Proteomics	1.0	3.32841
SLC27A2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00659561
GTEX-WFJO-0005-SM-3GIKY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.07159
WRNIP1	Pathway Commons Protein-Protein Interactions	1.0	null
GSE222758_0_v_2_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE255432_4_v_0_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_GM12874_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_Brain Substantia Nigra	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GTEX-WFG8-0126-SM-4LVMH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.10681
MAZ_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE202434,GSE202438_12_v_5_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE65617_5_v_1_aire_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K54118345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33022
posteroventral (inferior) parietal cortex_17 pcw_F_12880	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.06101
Class I glutamine amidotransferase-like	InterPro Predicted Protein Domain Annotations	1.0	null
STAT3	ENCODE Transcription Factor Targets	1.0	null
BRD-K03154735	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06433
H3K4me3_B cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB415	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.19543
GP5D	DepMap CRISPR Gene Dependency	1.0	2.5798
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A3YN-06A-11R-A239-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
REST_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE139239_2_v_6_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K61733751	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15022
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.923648
GSE157594_0_v_7_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A29T-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE197948_2_v_0_atp7b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-NFK9-1726-SM-3TW8P	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15441
BRD-K84846130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33868
BRD-K51546355	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56517
Bendamustine_SW 1271	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.0253138
Simple lobule, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33287
RKO-E6	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CTCF_GM10248_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548ai	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
TAF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MYC_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TCF12_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
OCI-AML3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.11069
GTEX-RVPV-0006-SM-2TF6Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23527
NPRL2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00477586
POU5F1-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
PMC11214527-mmc5.xlsx-TP53-gene_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K55927371	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.40182
H3K27ac_fibroblast of lung_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TFAP2A	ENCODE Transcription Factor Targets	1.0	null
GTEX-TMZS-0006-SM-3DB8G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40382
Central amygdalar nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.53077
inferior olive, dorsal nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.935985
Adenocarcinoma of lung_Lung Tissue_GSE1037	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.57991
pancreas	GTEx Tissue Gene Expression Profiles	-1.0	-0.972319
K562_AG-14361_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0157226
GSE167956_1_v_0_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
LN319	DepMap CRISPR Gene Dependency	1.0	2.5586
TAF1_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_SOX9_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CZ-4860-01A-01R-1305-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me1_cortical plate_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-POMQ-0006-SM-33HBY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12079
H3K4me3_WI38_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_fibroblast of foreskin _hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS1	ENCODE Transcription Factor Targets	1.0	null
ELK4_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MOLM16_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	3.94175
CTCF_fibroblast of upper leg skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-DS-A7WF-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MCF7_UNC0631_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0140064
Supraoptic nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.36917
POLR2AphosphoS5_U-87 MG_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE239688_2_v_1_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
dorsal motor nucleus of the vagus (vagal nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.51757
bonemarrow_6b	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.33167
valproic acid_homo sapiens_gpl96_gds1050	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-329	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
BRD-K60429174	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25002
600MPE	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	1.17178
CX-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.20894
PMC8481886-Table_2.xlsx-A_subsets-common_MSC_AF_MSC_UdRPC_MSC	Rummagene Transcription Factor Associations 2026	1.0	null
A549_Gandotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0128746
GBX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.9346
COLO-704	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.89021
GSE128634,GSE128636_2_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE230744,GSE237803_5_v_3_hira_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-Enh_vs_AA-all_DE-Aza_atRA_DE_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
TLCD3A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16374
NEK2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08895
GSE135350_3_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prostate cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.156
GSE216538_0_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of protein targeting to membrane	GO Biological Process Annotations 2015	1.0	null
GSE142210_3_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PAX5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NTERA2CLD1	DepMap CRISPR Gene Dependency	1.0	4.45213
GSE210225_0_v_1_inosine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-T5JC-0011-R1A-SM-32PM6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.961318
GSE149075_1_v_9_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of cell motility	GO Biological Process Annotations 2015	1.0	null
H3K4me3_CD4+ CD25- IL17+ PMA-Ionomcyin stimulated Th17 Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K09110452	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45015
GSE100316_7_v_6_mtor_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
pyrazinamide_mus musculus_gpl6246_gse48027	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
SHOX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.7635
DETROIT 562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09057
Parabrachial nucleus, medial division, external medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.35959
KMM1	CCLE Cell Line Gene CNV Profiles	1.0	1.82284
GSE196699_7_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-QMRM-0005-SM-3NB2A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.22019
SOHLH2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.8652
GTEX-TML8-0926-SM-4DXSJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825383
TRIM69	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00536961
AGTR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00461074
GSE213632_3_v_6_acod1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K44432556_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
VZ in primary visual cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15975
MBD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE112860_0_v_7_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Lobules IV-V, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12284
MAFK_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K04669648	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17176
CTCF_GM12868_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
pineal body	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.63395
GSE151083_0_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC6815046-13073_2019_678_MOESM4_ESM.xlsx-TCF20-Unnamed_0_TCF20	Rummagene Transcription Factor Associations 2026	1.0	null
GSE165682_4_v_3_ptbp1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184892_4_v_2_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE148692,GSE148695_2_v_4_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
VIIB, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.925542
UNC13A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14895
GSE48812_9_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
subpallial amygdala	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17729
TAF1_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H1930	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.47461
EP300_osteoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.91074
GSE149123,GSE149128_2_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Placenta	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
HDAC2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S7SE-0011-R5A-SM-2XCDA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.42136
REST_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hypothalamus	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	1.29364
496100474_FWM_possible Alzheimer's disease_TBI_89_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.03983
CTCF_GM10266_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 255.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.008
GSE139975_3_v_1_rnf2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SP4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PNPO	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00567168
H-89-6921	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_bronchial epithelial cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4699-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
BRD-K71496240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.98701
GSE114685_1_v_0_grin2b_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE116810_2_v_0_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
Crus 1, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.95901
parasolitary nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.27239
Skin Cutaneous Melanoma_SKCM_TCGA-D3-A2J7-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MAX_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A55574211	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50424
morantel-1798	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-VP-A87B-01A-11R-A352-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
1464_CDYL_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.72764
RNF2	ENCODE Transcription Factor Targets	1.0	null
occipital pole, left, lateral aspect	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.4807
KDM1A	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-516b	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
H3K4me3_CD4+ CD25+ CD127- Treg Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE118548_1_v_2_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
mRNA_NRIP1_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
BRD-A73605923_-666_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_GM12874_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSB-0005-SM-3LK7C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.95722
GSE226316_1_v_2_tead2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SRF	ChEA Transcription Factor Targets	1.0	null
Tuberomammillary nucleus, ventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.19328
BRD-K07781811	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1584
GTEX-QMR6-0011-R6A-SM-32PKP	GTEx Tissue Sample Gene Expression Profiles	1.0	3.75804
GTF2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE234043_3_v_1_abcb1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE138815,GSE138817_0_v_2_kdm6a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
UACC-812	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898719
GTEX-R55C-0826-SM-48FCL	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831495
OTX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.8209
H3K27ac_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE60691_2_v_3_glutamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
gigantocellular reticular nuclei	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.81628
ASH1L	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.11502
H3K4me3_GM12865_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE200388_0_v_1_gemin5_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCI-H1573	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.14907
GSE160817_5_v_1_slamf6_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE128634,GSE128636_2_v_0_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
SIN3A_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63573625	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18051
GSE129241_3_v_6_valproic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HEL_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.16626
VZ in dorsomedial parietal cortex (area 7m)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.086
GSE147876,GSE147877_4_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE176555,GSE176556_1_v_0_acriflavine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K63665694	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50641
GSE88819_0_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me2_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QXCU-1726-SM-2TC6L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876954
GTEX-T8EM-0006-SM-3DB71	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04771
RBBP5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RPL7L1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10272
H3K36me3_cardiac mesoderm_hg19_6	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Sox17	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.6248
K562_SB431542_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0157077
BCLAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE75976_3_v_9_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
K562_Tazemetostat_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0161794
H3K36me3_NT2-D1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDVN-0426-SM-48TZ6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07959
NCI-H2596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.18567
Bladder Urothelial Carcinoma_BLCA_TCGA-XF-A8HG-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-N7MT-0007-SM-3GACQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03056
BRD-K67808578_1391-0741_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CEBPB_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55G-0126-SM-48FDS	GTEx Tissue Sample Gene Expression Profiles	1.0	1.38679
primary somatosensory cortex (area S1, areas 3,1,2)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.87947
PMC8650352-JCB_202012097_DataS1.xlsx-VHL_KD_filteredPeptides-Gene_names_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GSE161170,GSE161268_1_v_3_med1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
DZIP3	Pathway Commons Protein-Protein Interactions	1.0	null
REST_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE188458_2_v_1_hydrogen peroxide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_7_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_brain microvascular endothelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
K-562	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.75712
hsa-miR-3622b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
GSE151612_4_v_2_pracinostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE210101,GSE210114_7_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE244710_3_v_2_srsf1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PL18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
HHEX	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00477828
paraventricular nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.47129
BRD-K61934967	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07119
GTEX-NL3H-0011-R10A-SM-2I3E9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927421
SW 403	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.24396
POU2F1::SOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.7149
BRD-K12035825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25941
GSE158834_10_v_9_palm_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
ES-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33082
Cell type cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.068
GSE158632_2_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me2_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF7L2_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-548d-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
GTEX-O5YT-0007-SM-32PK7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.3955
GSE205070_1_v_6_mertk_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GBA1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.34526
NCI-H596	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13123
H2AFZ_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_PFI-1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0219433
Acute Myeloid Leukemia_LAML_TCGA-AB-2993-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE210885_2_v_1_klf4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GATA1::TAL1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	33.9461
PMC9992472-41467_2023_36735_MOESM7_ESM.xlsx-SOX11_ChIP_in_IMR-32-Unnamed_12_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
GSE214823,GSE214824_3_v_1_crtc2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Paraflocculus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2083
primary visual cortex (striate cortex, area V1/17)_23 yrs_M_12300	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.34761
H3K4me3_Caco-2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
sublayer 6a of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.38865
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.43805
LNCaP cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.251
GSE168473_0_v_1_isoniazid_human	RummaGEO Drug Perturbation Signatures	1.0	null
VCAN	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00473709
PMC10244410-41467_2023_39054_MOESM5_ESM.xlsx-PIE-LIN28B-GeneSymbol_LIN28B	Rummagene Transcription Factor Associations 2026	1.0	null
X, left, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.36842
hsa-miR-4684-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
VPS13C	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00546663
GSE120370_4_v_3_thrombin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K34581968_BMS-536924_SW620_6.0_h_11.1_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_bronchial epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
STAT3-23295773-U87-HUMAN	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE135514_2_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE223893_11_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
Agranular insular area, dorsal part, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2185
GSE175787_13_v_10_rhoc_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE139455_2_v_5_stat3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2895-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r9BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.76556
TEAD4_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE217552_3_v_0_fisetin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE235066_4_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FOXP2	ENCODE Transcription Factor Targets	1.0	null
H3K27ac_Brain Anterior Caudate	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE80446_2_v_1_anakinra_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_MCF-7_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE142210_3_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
FTC133	DepMap CRISPR Gene Dependency	1.0	2.72825
primary auditory cortex (core)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.30225
GTEX-RM2N-0126-SM-48FDD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21431
MYF6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.038
positive regulation of anion transmembrane transport	GO Biological Process Annotations 2023	1.0	null
BRD-K46171140	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58023
GSE168401_1_v_3_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
scoulerine-1742	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
MAX_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228017_0_v_1_parthenolide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Basophilic leukemia cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.617
COV413A	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.904542
SNU1214	CCLE Cell Line Gene CNV Profiles	-1.0	-1.36549
Duodenum Mucosa	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	1.0	1.09453
interpositus (intermediate) nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.905143
BRD-K84937637_A-275_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
fasciola cinerea	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04135
PMC9314667-Table_1.xlsx-Regulons-FOSL1_FOSL1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A24021119_NCGC00183696-01_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.154
K562_Pelitinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0147078
GSE181959_3_v_2_dextran_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K77894681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0631
CTCF_epithelial cell of proximal tubule_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH2291	DepMap CRISPR Gene Dependency	1.0	2.34522
GSE166315_5_v_0_docetaxel_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_WERI-Rb-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZEB1	ENCODE Transcription Factor Targets	1.0	null
GSE234637_2_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-POYW-0006-SM-2XCF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.974322
4578_LIG1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	1.21033
spleen	GTEx Tissue Gene Expression Profiles	-1.0	-0.874861
PMC4149371-pone.0105180.s010.xls-SOX2-GENE_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
NCO2	CCLE Cell Line Gene CNV Profiles	-1.0	-1.74884
PMC9377669-tx1c00392_si_002.xlsx-Retinol-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-TSE9-0011-R8A-SM-3DB7R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.829569
BRD-K49472569	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.37851
anterior (rostral) cingulate (medial prefrontal) cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.34187
BRD-K83699731	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.81143
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1Z0-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RAD21_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
KCTD3	Pathway Commons Protein-Protein Interactions	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MS-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE168401_1_v_0_harmine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K54879095	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.16244
Brain Lower Grade Glioma_LGG_TCGA-DU-7015-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
D-423MG	COSMIC Cell Line Gene CNV Profiles	1.0	2.09117
CUX1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
m8	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	1.448
K562_AT9283_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0118935
GSE165647_5_v_1_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
regulation of intracellular protein transport	GO Biological Process Annotations 2015	1.0	null
GSE162739_6_v_1_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
LOVO	DepMap CRISPR Gene Dependency	1.0	6.46099
KYSE-270	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13187
GSE207787_1_v_4_pdha1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-N7MS-0007-SM-2D7W1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19592
GTEX-W5WG-0006-SM-3GIJT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.25516
CHD7	ENCODE Transcription Factor Targets	1.0	null
GTEX-X4XX-0011-R8B-SM-46MWM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01929
GSE157555,GSE157556_0_v_6_foxa2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4535	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
GSE249098_1_v_0_mthfd1l_human	RummaGEO Gene Perturbation Signatures	-1.0	null
white matter of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14926
BHLHE40_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE130246_2_v_0_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2822-03A-01T-0734-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE202134_0_v_1_rbm39_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Accessory olfactory bulb, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.45846
PMC9377669-tx1c00392_si_002.xlsx-Entinostat-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
NCI-H460	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.00205
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EF-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE169697,GSE169725_0_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
gracile nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.37537
Acute Myeloid Leukemia_LAML_TCGA-AB-3009-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_GM12878_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55D-0006-SM-3GIJS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19724
GSE236262_0_v_3_trim28_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Central nervous system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
LS411N	DepMap CRISPR Gene Dependency	1.0	6.41207
GTEX-WVLH-0011-R11A-SM-3MJFO	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880656
MAP3K7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00541885
GTEX-WVLH-0011-R6A-SM-3MJFZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29405
BRD-K68086276	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37736
HCFC1	ENCODE Transcription Factor Targets	1.0	null
MDA-MB-175-VII	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.982511
nucleus accumbens, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.18991
placenta_6c	HPA Tissue Sample Gene Expression Profiles	1.0	1.79228
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-GV_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_cardiac mesoderm_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-R55E-0011-R6A-SM-2TC5T	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23296
A549_SRT1720 HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0273155
GSE119978,GSE180930_6_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DMS 79	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.02425
Prostate adenocarcinoma_PRAD_TCGA-EJ-5518-01A-01R-1580-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE215351,GSE215794_4_v_0_kdm8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K81142122_STK249718_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE164757,GSE164759_4_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Lomustine_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0148683
SP1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE153010_1_v_0_sprr2f_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE188870,GSE188871_0_v_2_kat7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE210655_3_v_2_cisplatin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_U-87 MG_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148692,GSE148695_2_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
layer IIIb of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.71695
17683608-TableS3	GeneSigDB Published Gene Signatures	1.0	null
IX, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.45063
an3ca	HPA Cell Line Gene Expression Profiles	1.0	1.07887
Adrenocortical carcinoma_ACC_TCGA-OR-A5JZ-01A-11R-A29S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE121866_0_v_2_six4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
meticrane-1792	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RASAL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00437569
CTCF_GM12867_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P44H-0011-R5A-SM-2XCEX	GTEx Tissue Sample Gene Expression Profiles	1.0	2.8263
HNF4G_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-3180-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
positive regulation of cellular protein localization	GO Biological Process Annotations 2015	1.0	null
GTEX-OHPL-1326-SM-3MJGG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22085
BRD-K60713831	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.80443
Idiopathic dilated cardiomyopathy	GWAS Catalog SNP-Phenotype Associations 2025	1.0	0.530103
GTEX-PW2O-0006-SM-2I3DV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.09638
ELK1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZC3H11A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIK3C3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00716199
GSE129725_1_v_5_bmal1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
reuniens nucleus (medioventral nucleus) of thalamus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.39191
GTEX-XYKS-0005-SM-4BRUD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49935
GSE175787_11_v_9_rhoc_human	RummaGEO Gene Perturbation Signatures	1.0	null
NFIC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	44.9812
BRD-K94913575	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29122
positive regulation of protein localization to membrane	GO Biological Process Annotations 2023	1.0	null
BRD-K64317740	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15228
PMC10800016-table_s3_20230913_ddad186.xlsx-DUX4-aff_II-Unnamed_1_DUX4	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QMR6-0011-R8A-SM-32PKJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91354
STAT3_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147366_3_v_2_med13_human	RummaGEO Gene Perturbation Signatures	1.0	null
inferior colliculus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.1332
SP4	ENCODE Transcription Factor Targets	1.0	null
BRD-K51662849_GM6001_HA1E_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
hsa-miR-492	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
BHLHE40	ENCODE Transcription Factor Targets	1.0	null
SNUC1	DepMap CRISPR Gene Dependency	1.0	2.53666
GTEX-SJXC-0005-SM-2XCE7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.11576
GTEX-WOFM-0005-SM-3MJF3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.79912
A549_Cimetidine_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142254
TCF12_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
STRAP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0269
CTCF_brain microvascular endothelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JIYOYE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72253
MEL18_DN.V1	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
GSE229973_4_v_2_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-Q734-0426-SM-48TZX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.912328
GSE212299_2_v_1_abi3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Postsynaptic cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.844
CTCF_endothelial cell of umbilical vein_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
2765_ETV5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.652931
GTEX-XOTO-0011-R7B-SM-4B64R	GTEx Tissue Sample Gene Expression Profiles	1.0	0.974999
H3K4me2_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r7BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76551
Prostate adenocarcinoma_PRAD_TCGA-EJ-7330-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K9ac_ES-E14_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE154464_0_v_3_cdk6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A20H-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
DOHH-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95802
r9 part of paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.8786
ctnnb1_21914722_ls174t_lof_human_gpl570_gds4386	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	1.39495
GSE216273,GSE216292_14_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
NDUFS3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00623384
GSE158834_10_v_9_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_H1	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-A18825024	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24013
MAGED1	Pathway Commons Protein-Protein Interactions	1.0	null
TAL1	ENCODE Transcription Factor Targets	1.0	null
GSE167886_3_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HOXB7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.2434
LY-294002-2699	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TIMP3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.06951
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05972
HT1376	DepMap CRISPR Gene Dependency	1.0	2.91283
BRD-K21232462	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3269
AMY2A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00604787
NR2F2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OOBJ-1026-SM-3NB2L	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.95051
H3K4me3_bone marrow_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-L-Thyronine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GSE211215_1_v_0_akr1b1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K89141455	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01578
A549_PCI-34051_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0105949
Lung squamous cell carcinoma_LUSC_TCGA-22-5477-01A-01R-1635-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-X585-2426-SM-46MW2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.832959
GSE213650_3_v_2_everolimus_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE101239_5_v_0_valproic acid_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE81803,GSE81912_0_v_5_fmr1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE164757,GSE164759_1_v_2_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE87862_0_v_1_mov10_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
SRY-25088423-EMBRYONIC GONADS-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
K562_S3I-201_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0168608
K562_Ellagic acid_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0170542
GSE205070_2_v_7_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ASIC2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00586945
BIRC2	Pathway Commons Protein-Protein Interactions	1.0	null
CTCF_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
6792_PRPF19_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.670916
A549_Iniparib_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0172208
K562_Ki16425_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0173089
H3K4me3_fibroblast of gingiva_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
NCI-H2795	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.66777
GSE225869_3_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K70158474	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30414
A549_FLLL32_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0164384
NFIC_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.45591
NDN	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.54462
GTEX-X261-3226-SM-3NMC3	GTEx Tissue Sample Gene Expression Profiles	1.0	0.918964
Lung adenocarcinoma_LUAD_TCGA-55-6712-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
COLO 857	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.28743
POLR2A_K562_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F4_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K34701680	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01041
trastuzumab_homo sapiens_gpl6947_gse31432	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
superficial stratum of r8BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.15668
POLR2A_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPN-0011-R5A-SM-2I5FF	GTEx Tissue Sample Gene Expression Profiles	1.0	0.880177
G130	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.955444
OVISE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.09057
HS 683	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.06539
GTEX-RM2N-0006-SM-2TF5H	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23387
MDH2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00415999
537_ARPC3_P1	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.524449
GTEX-WCDI-0005-SM-3NB2M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.72557
striatum_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.32825
superficial stratum of PCPD	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04578
ZHX3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.77541
GTEX-S7PM-0006-SM-3NM8C	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09545
Perturb_15726_KO_Il1rl1_SRP274117	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.37457
guanethidine-1554	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE149901_2_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE101112_0_v_4_j147_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-4cell_CTCF-Unnamed_2_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K16189898_CHIR-99021_SKBR3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ELF1_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TOLLIP	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XMD3-0006-SM-4AT5X	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06741
BRD-K72379955	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.22317
GSE211262,GSE211263_0_v_1_pbrm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE159893_2_v_0_genistein_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of the aortic adventitia_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE207728,GSE207808_2_v_1_c646_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ZNF382	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1988
H3K4me2_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
striatum_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.957904
GSE217452_3_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
CA2 field, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.03518
Perturb_11106_KO_Wtap_SRP310501	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	20.0
CDK10	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0077457
BRD-K83684822	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27451
GTEX-U3ZN-0006-SM-3DB7Y	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32437
MZ in retrosplenial cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.32363
CTCF_BE2C_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
flunixin-2552	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7327-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-UTHO-0006-SM-3NMCC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16529
BRD-K76067434	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.18959
regulation of protein transport	GO Biological Process Annotations 2015	1.0	null
GSE186065_0_v_1_sirt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE158834_12_v_8_palmitic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
striatum_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.00815
SAP25	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16483
RNF182	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38815
ventral isthmic part of dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16948
TYK2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0048657
BRD-K40222892	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.88515
EP300_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
nucleus accumbens, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.35414
GTEX-PVOW-0006-SM-3NMB8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.341
H3K4me3_fibroblast of pedal digit skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-1426-SM-32PLA	GTEx Tissue Sample Gene Expression Profiles	1.0	1.0791
Head and Neck squamous cell carcinoma_HNSC_TCGA-CR-7365-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ChIP_POU5F1_18347094	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GTEX-U8XE-0726-SM-3DB8O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01412
hsa-miR-1280	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
BRD-K33676730_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K27ac_CD4+ CD25- CD45RA+ Naive Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
H3K9ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
red nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.837213
H3K4me3_SK-N-SH_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-617	TargetScan Predicted Conserved microRNA Targets	1.0	0.274552
GSE130676_0_v_2_suds3_human	RummaGEO Gene Perturbation Signatures	1.0	null
OVCA 432	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.984588
GSE211128_7_v_6_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217115_3_v_0_alectinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H441	COSMIC Cell Line Gene CNV Profiles	1.0	2.09117
CIB1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00596247
Sarcoma_SARC_TCGA-HB-A43Z-01A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE221020,GSE221023_2_v_1_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K40732885	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31308
BRD-K44696459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27148
GTEX-XBEC-0006-SM-4AT5T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.41139
GSE77108_0_v_9_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
MAX_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95795
hsa-miR-3942-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.361556
BRD-A62025033_temsirolimus [CI779]_SW948_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K67470788_5867767_PC3_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE211215_1_v_0_pemetrexed_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WRHU-0006-SM-3MJF6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.03535
BRD-K12517207	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01689
EB2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.37341
GSE145215_0_v_3_krt13_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CAL-148	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.846068
GTEX-WWYW-0011-R10A-SM-3NB35	GTEx Tissue Sample Gene Expression Profiles	1.0	0.987744
BRD-K13679727	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1478
BRD-K62466453_NCGC00182388-01_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
cinnarizine-1558	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_cardiac muscle cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RNOR-0011-R7A-SM-2TF4V	GTEx Tissue Sample Gene Expression Profiles	1.0	1.91089
hsa-miR-4755-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
amygdalohippocampal transition zone, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.03148
H3K4me3_fibroblast of villous mesenchyme_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-624	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
PMC9377669-tx1c00392_si_002.xlsx-Leflunomide-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_GM18526_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
corticoid layer of TuStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01524
Uterus	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.325
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.42611
MCF7_Decitabine_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0136372
H3K4me3_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ST3GAL5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00385317
RAD21_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K82508779	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.07185
GSE180185_9_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
hsf1_17216044_hela_lof_human_gpl571_gds1733	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.645257
Lung adenocarcinoma_LUAD_TCGA-97-7552-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-XMK1-0008-SM-4GICF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.04915
BRD-K31484631_1109_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE234637_2_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
primary auditory cortex (core)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.926123
BRD-K60024823	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18215
GSE169205_0_v_6_sirt5_human	RummaGEO Gene Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-TM-A7CA-01A-21R-A33Z-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE199255,GSE199356_6_v_1_pds5a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
S1P_Deficiency_GDS3654_521_mouse_Liver	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE146687_2_v_5_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
DHX8	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-3.39287
Bladder Urothelial Carcinoma_BLCA_TCGA-BL-A0C8-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.38668
skeletalmuscle_e	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.32847
BRD-A35588707_TENIPOSIDE_A375_24.0_h_1.25_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE127790_10_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
RERFLCAD2	CCLE Cell Line Gene CNV Profiles	-1.0	-2.15104
HCC1395	CCLE Cell Line Gene CNV Profiles	1.0	1.90397
ZKSCAN1	ENCODE Transcription Factor Targets	1.0	null
estradiol_homo sapiens_gpl570_gds3283	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE92614_1_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE115542_5_v_3_digoxin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_9_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE196671_6_v_1_obox4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K70549064_EI-156_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K37760698	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13129
CREB1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6393-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ABCB6	Pathway Commons Protein-Protein Interactions	1.0	null
RUNX2-24655370-MC3T3E1-MOUSE-BONE	ChEA Transcription Factor Targets 2022	1.0	null
MYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.602
Crus 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.53171
TTC39C	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.41361
HN	CCLE Cell Line Gene CNV Profiles	-1.0	-1.34864
GSE87412,GSE92423_3_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PSMG4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.49026
GTEX-Q2AG-0011-R3A-SM-2HMJ9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.00079
Central amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43833
Vermal regions	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.06539
BRD-K51215422	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58501
H2AFZ_mammary epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE167886_2_v_1_chd7_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE48812_0_v_10_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3940-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.843347
OVCAR5	CCLE Cell Line Gene CNV Profiles	1.0	1.74258
H3K4me3_fibroblast of upper leg skin_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PMC10602967-18_2023_4927_MOESM3_ESM.xlsx-MBNL1_KD_HFE-145-Unnamed_1_AR	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-QMR6-0011-R11A-SM-32PKK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01201
hsa-miR-338-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
hippocampus (hippocampal formation)_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.947257
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.955829
diazoxide-1368	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H2AFZ_fibroblast of dermis_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-S341-0006-SM-3NM8D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.09348
CTCF_HeLa-S3_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_A549_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K63998843	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.73257
GTEX-VJWN-0005-SM-3GIKF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-3.22225
GSE134986_2_v_8_oma1_human	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in hypothalamic portion	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05174
BRD-K71592817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.63238
H3K4me3_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZMIZ1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NFATC1	ENCODE Transcription Factor Targets	1.0	null
SIN3A_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE94849_6_v_2_pinometostat_human	RummaGEO Drug Perturbation Signatures	1.0	null
4716_LUC7L3_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.716643
CLEC4A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00587856
SMC3	Pathway Commons Protein-Protein Interactions	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-HD-7753-01A-11R-2081-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-BC-A112-01A-11R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
regulation of cellular component organization	GO Biological Process Annotations 2015	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Valproic_Acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7738-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE208350_4_v_1_fgfr1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158632_2_v_1_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE130081,GSE130082_0_v_1_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
superficial stratum of r10BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.57813
GTEX-OXRK-0006-SM-2HML1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47408
GSE216043_11_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
SP2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Cell periphery	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Lung adenocarcinoma_LUAD_TCGA-97-7554-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
primary somatosensory cortex (area S1, areas 3,1,2)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.37462
POLR2A_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RBFOX2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00422324
BRD-K85668200	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30732
POLR2A_testis_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
DB-54-GQ68_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.236669
GTEX-QVUS-0006-SM-3GAE8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.45621
HOXA6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.3918
BRD-K08730943	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.57171
A549_GSK1070916_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0111987
cerebellar nuclei of CbV	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.01354
Lung squamous cell carcinoma_LUSC_TCGA-58-A46M-01A-11R-A24H-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-IE-A6BZ-01A-11R-A30C-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K87316858	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.17155
BRD-A17831693	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.8505
arcuate nucleus of the hypothalamus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.17385
15843827-TableS11	GeneSigDB Published Gene Signatures	1.0	null
17638893-SuppTable2	GeneSigDB Published Gene Signatures	1.0	null
PMC4149371-pone.0105180.s010.xls-NANOG-GENE_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
SUPT6H	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.8096
HOP92	CCLE Cell Line Gene CNV Profiles	1.0	1.58844
CTCF_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_336_OE_PBX1_SRP389513	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
primary somatosensory cortex (area S1, areas 3,1,2)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.98788
diclofenamide-3027	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE68156_0_v_5_dextran_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE171837_3_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Globus pallidus, external segment	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02728
MXI1	ENCODE Transcription Factor Targets	1.0	null
Skin - Sun Exposed (Lower leg)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.903566
layer 4 of ERCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.00636
GSE89018_6_v_14_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
bmi1_17452456_medulloblastoma_lof_human_gpl570_gds2724	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	1.0	0.488865
ZFP28	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.08644
CTCF_GM12873_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K00418890	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25887
UBC	Pathway Commons Protein-Protein Interactions	1.0	null
AIP	Pathway Commons Protein-Protein Interactions	1.0	null
nervous system	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-2cell_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.917881
BCL3	ENCODE Transcription Factor Targets	1.0	null
FOXA1_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of lung_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XUW1-0005-SM-4BOQ7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.01262
NCI-H1975	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GTEX-TSE9-3026-SM-3DB76	GTEx Tissue Sample Gene Expression Profiles	1.0	0.904559
ELK4	ENCODE Transcription Factor Targets	1.0	null
GTEX-S7SE-0011-R8A-SM-2XCDG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.12025
BRD-K92399035	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48033
dorsolateral isthmic part of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.96174
LMX1B	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	18.5737
GNA11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24581
HS 69ST	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.60633
Brain stem	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.236
BRD-K03816923_Rottlerin_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE121198,GSE129779_3_v_1_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
RH30	DepMap CRISPR Gene Dependency	1.0	5.4824
MCF7_Mocetinostat_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00972644
PMC3507169-supp_bio.20121594_bio.20121594-tableS1.pdf-17-BAZ2B_BAZ2B	Rummagene Transcription Factor Associations 2026	1.0	null
PMC10592471-NIHMS1912771-supplement-7.xlsx-D-HEp3-Enh_vs_AA-up_genes-AA_up_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-5364-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Amygdala	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.6591
GSE158632_3_v_1_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SHSYSY+RA	BioGPS Cell Line Gene Expression Profiles	1.0	1.61105
periventricular stratum of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.14845
GSE234637_1_v_0_ikzf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A3F5-06A-11R-A20F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-T2IS-0011-R11A-SM-32QPC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.950507
GSE242333_0_v_2_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
cerebellar cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.906034
NCI-H23	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K95551067	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47018
GSE60837_2_v_4_bcl9_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
striatum_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.43253
CHRNB2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.30968
NPLOC4	Pathway Commons Protein-Protein Interactions	1.0	null
LEFTY1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00402953
GTEX-NPJ7-0011-R1a-SM-3GACT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.924401
GTEX-W5WG-1126-SM-4LMK4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.54807
GSE206784_3_v_4_ninl_human	RummaGEO Gene Perturbation Signatures	1.0	null
SFRP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00542408
BRD-K72694472	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.09942
PMC9377669-tx1c00392_si_002.xlsx-Ranitidine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
ACTB	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.07584
RELA_GM15510_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCIH1755	DepMap CRISPR Gene Dependency	1.0	3.76838
MCF7_2-Methoxyestradiol_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0128468
GSE216043_7_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PKNOX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	32.092
striatum_19 yrs_F_12832	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.27869
USF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
regulation of cellular localization	GO Biological Process Annotations 2015	1.0	null
BRD-K79032360	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08891
PMC6987220-41467_2020_14312_MOESM5_ESM.xlsx-P53_Spheres-8_names_TP53	Rummagene Transcription Factor Associations 2026	1.0	null
A549_AZD1480_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0170789
GSE128333_4_v_5_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
MCF7_SL-327_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.020569
BRD-K27949240	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34653
Perturb_6466_KD_NR4A2_ERP130094	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-17.7471
mediodorsal nucleus of thalamus_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.15509
H3K4me3_cardiac mesoderm_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
HCV JFH-1_18Hour_20200238_GSE20948	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.25648
GSE217405_0_v_2_egfr_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
tail of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.40429
Lobules IV-V, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05635
regulation of establishment of protein localization	GO Biological Process Annotations 2015	1.0	null
U-2932	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.824228
PMC9843885-40478_2023_1507_MOESM6_ESM.xlsx-CIC-OE_TS603-Unnamed_1_CIC	Rummagene Transcription Factor Associations 2026	1.0	null
PMC9218776-ADVS-9-2104640-s002.xlsx-SIM_-_Nurr1-Nurr1_modulation_mediates_neuroprotective_effects_of_statins_SIM2	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-V1D1-1926-SM-4JBGX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839332
GTEX-QVUS-0011-R10A-SM-3GIK3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21182
H3K4me1_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ZKSCAN1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NB10	DepMap CRISPR Gene Dependency	1.0	2.63845
EZH2_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Divalproex Sodium_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126323
CREB1-20920259-GC1-SPG-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
GSE125219,GSE125221_3_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC5927328-NIHMS77085-supplement-Table_S4.xlsx-Table_S4A_LPS_induced_genes_GO-Unnamed_15_IRF6	Rummagene Transcription Factor Associations 2026	1.0	null
GSE224969,GSE224971_3_v_7_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K47228832	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30762
BRD-K81463178	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.30861
KMS-12-BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.890135
GSE147662_2_v_5_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Paroxetine-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-S7SE-0011-R6A-SM-2XCD9	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30636
BRD-K54606188_(+)-JQ1_A375_24_h_0.04_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PC-14	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.57811
IM9	DepMap CRISPR Gene Dependency	1.0	2.69901
NFIC	ENCODE Transcription Factor Targets	1.0	null
BRD-K50710722	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07515
GTEX-WK11-0006-SM-3NB3J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04935
MOLP-8	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.50431
Lung squamous cell carcinoma_LUSC_TCGA-56-7223-01A-11R-2045-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LK2_LUNG	CCLE Cell Line Proteomics	1.0	2.58271
GSE178532_1_v_3_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SERPINB8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0049801
POLR2A_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HEL	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.824203
Embryonic structure	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
EN1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.5835
HCC202	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.710785
BRD-K11741103	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.27887
19061838-TableS7	GeneSigDB Published Gene Signatures	1.0	null
cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12193
BRD-A19195498_TRIMIPRAMINE MALEATE_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K59847773	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.6774
GSE112860_0_v_2_prdm16_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE107956,GSE107957_0_v_1_ythdf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_HCT116_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bed nuclei of the stria terminalis, anterior division, rhomboid nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.75962
BRD-K57879743	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.05003
regulation of locomotion	GO Biological Process Annotations 2015	1.0	null
ELMOD3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0567
striatum_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.28184
P31-FUJ	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.37533
GTEX-WFON-0005-SM-3NMC9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.50006
hsa-miR-4282	TargetScan Predicted Conserved microRNA Targets	1.0	1.11641
GSE147876,GSE147877_2_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K64970964	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04538
hsa-miR-3160-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
r1 alar plate	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.23228
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02059
sirolimus_homo sapiens_gpl6244_gse15703	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE153836_11_v_9_fluoxetine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
15902281-TableS1d	GeneSigDB Published Gene Signatures	1.0	null
H3K27ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K39420925	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13614
GSE245270_1_v_5_isoproterenol_human	RummaGEO Drug Perturbation Signatures	1.0	null
OR52N4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00499503
PFKL	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00773231
GTEX-WH7G-0005-SM-3NMBX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10334
BRD-K12184916_NVP-BEZ235_MDAMB231_3_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6403-01A-11R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K46348476	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33457
GSE233566_1_v_2_braf_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_GM06990_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE68925_1_v_0_fasudil_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE168807_0_v_7_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE71674,GSE71676_0_v_2_cbfa2t2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K9me1_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Trophoblast stem cell	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.83
GTEX-T6MO-0126-SM-4DM6X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22493
hsa-miR-548w	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
dorsolateral part of Med	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4485
orbital frontal cortex_12 pcw_F_13060	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.881924
GSE189683_3_v_2_rif1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_12175_Mut_PLK4_ERP132994	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	8.35368
LIVF001-027	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.70389
MBD4	ENCODE Transcription Factor Targets	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7123-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ventrolateral prefrontal cortex_19 pcw_F_12885	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.02472
central amygdaloid nucleus, medial part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.25241
GTEX-XPT6-0006-SM-4B66Q	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47792
Perturb_10712_KO_Nrf2_SRP336215	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	3.2535
BRD-K43449580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.48488
EP300_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PML_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119978,GSE180930_3_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
intermediate isthmic part of the dorsal raphe nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.26937
HCC1500	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-1.30819
regulation of cell migration	GO Biological Process Annotations 2023	1.0	null
GTEX-P44H-0011-R10A-SM-2XCEK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19175
GSE224969,GSE224971_0_v_5_chtop_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-SE5C-0006-SM-4BRW5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.90988
GSE112995,GSE132079_1_v_0_ezh2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_8909_KD_CCDC144NLAS1_SRP135858	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
A549_Rucaparib_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0131186
diloxanide-3062	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-X3Y1-0006-SM-3P5ZG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23536
PL-21	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.76169
EKVX	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.957781
PMC9195629-Table1.xlsx-Supplementary_Table_1-JUN_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_Panc1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE222758_0_v_4_clofazimine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
JHH1	CCLE Cell Line Gene CNV Profiles	1.0	1.37276
GTEX-T2IS-0011-R6A-SM-32QP2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22115
FAF2	Pathway Commons Protein-Protein Interactions	1.0	null
HCC2911	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.51075
GSE134896_0_v_3_progesterone_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K76515685	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02411
A549_Roxadustat_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0167598
GSE190950_1_v_0_nono_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K9ac_liver_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K41895714_AS-605240_A549_24_h_3.33_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-P4QT-1326-SM-3NMD3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58958
H3K4me3_HeLa-S3_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
negative regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
SRF-21415370-HL-1-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
PNCK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.20014
Mesothelioma_MESO_TCGA-MQ-A6BS-01A-12R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K02162441	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.03051
BRD-K98880643	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.54926
mantle zone of AOB	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2185
CEBPD_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE125014_6_v_5_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
bonemarrow_6a	HPA Tissue Sample Gene Expression Profiles	-1.0	-1.6158
TEAD4	ENCODE Transcription Factor Targets	1.0	null
BRD-K87790666	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.06883
Perturb_13918_OE_PPARGC1A_SRP265351	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-QVJO-0006-SM-2S1RC	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.83856
GSE216043_3_v_6_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.30424
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SQ-A6I4-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE158715_3_v_0_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_erythroblast_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VUSG-0006-SM-3GIK9	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978688
GSE239688_2_v_5_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K03618428_PP-110_SKMEL28_6.0_h_22.2_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_ES-Bruce4_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE203060_0_v_2_kdm4c_human	RummaGEO Gene Perturbation Signatures	1.0	null
terete nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17729
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZS-06A-12R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE261563_9_v_1_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE165334_2_v_0_dabrafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
TBL1XR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM19193_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11511861-41420_2024_2216_MOESM2_ESM.xlsx-siTAZ_myc_bound-MYC_targets_from_chipseq_atlas_at_least_2_chip-seqs_over_4_in_A459_MYC	Rummagene Transcription Factor Associations 2026	1.0	null
Peripheral_Blood_Mononuclear_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.51183
Lung squamous cell carcinoma_LUSC_TCGA-34-5927-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K82609503	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08744
GTEX-S341-0126-SM-4AD64	GTEx Tissue Sample Gene Expression Profiles	1.0	1.32078
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.61273
Paraflocculus, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.25371
PMC11925450-elife-96850-supp2.xlsx-DNMT1_KO_vs_DNMT1_L1TD1_dKO_res-Unnamed_0_DNMT1	Rummagene Transcription Factor Associations 2026	1.0	null
Medial amygdalar nucleus, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.39846
vitamin c_homo sapiens_gpl6884_gse16590	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE148263_6_v_0_trim3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE233679_14_v_9_nicotinamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE127790_5_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ZNF354A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.2049
KLF4	ChEA Transcription Factor Targets	1.0	null
KYSE-70	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.917887
SIN3A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57270624	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08827
H3K4me3_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K06724886	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7398
THAP11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40045
Spi1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	70.4495
OCI-AML5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.63357
amygdaloid complex_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.14222
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2MK-06A-11R-A18S-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K20373726	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.02998
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7886-01A-11R-2156-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-936	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.13535
CTCF_cardiac fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3000-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
MXI1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MDA-MB-361	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
GSE190186,GSE190188_0_v_10_apoe_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K27me3_megakaryocyte_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
A549_Divalproex Sodium_10然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0160026
GTEX-QEG4-0006-SM-2I5FY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.982999
TK	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18441
GSE103068_5_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
midodrine-1403	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A55594068_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
primary auditory cortex (core)_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.971479
PML_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221327_6_v_2_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182179_5_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
HCC202	DepMap CRISPR Gene Dependency	1.0	4.1072
BRD-K62692910	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03925
GSE239844_7_v_9_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-WL46-0011-R11A-SM-3MJFT	GTEx Tissue Sample Gene Expression Profiles	1.0	0.927043
YLPM1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00927835
YY1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
UBTF_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4680-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.257113
RNF2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of gingiva_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
internal granular layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.43741
CTCF_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_kidney epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119978,GSE180930_0_v_4_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Declive (VI), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.56479
sulpiride-1967	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of gingiva_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K15616905_CCCP_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOSL2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HOXA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.557
POLR2A_endothelial cell of umbilical vein_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
7252_RFK_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.709274
PMC7098486-mmc2.xlsx-Kgg_Quant_NGN2_AAVS_-_WCL-Unnamed_2_NEUROG2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me2_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
HS-SULTAN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.17985
GTEX-T5JC-0011-R10A-SM-32PM2	GTEx Tissue Sample Gene Expression Profiles	1.0	1.14689
BRD-K92202681	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.18229
head of caudate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0601
H3K4me3_bone marrow macrophage_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
COL4A5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00433216
4805_MAP2K7_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.29918
DIABLO	Pathway Commons Protein-Protein Interactions	1.0	null
BRD-K90686617	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.07361
adrenal gland	HPA Tissue Gene Expression Profiles	1.0	0.999889
Sarcoma_SARC_TCGA-KD-A5QT-01A-11R-A27Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NFYA	ENCODE Transcription Factor Targets	1.0	null
CTCF_HL-60_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
layer 5 of InsCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06338
SW982	DepMap CRISPR Gene Dependency	1.0	3.30317
K5	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	2.1538
Perturb_11378_KD_OGT1_SRP311080	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.32573
NCI-H716	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.01446
PITX3	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6374
ventrolateral prefrontal cortex_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.828897
GSE116354,GSE117379_3_v_5_cox2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R55D-1126-SM-48FEB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.874026
GSE224763_1_v_0_rif1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GA-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.72253
BRD-K47776393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04507
Crus II, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.25762
BRD-A31107743_89671_VCAP_24.0_h_0.09_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MAFA	MotifMap Predicted Transcription Factor Targets	1.0	null
hsa-miR-548ag	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
BRD-K62459624_T5212475_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-TKQ1-0006-SM-33HBI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.02071
GSE201309_4_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE102467_3_v_2_pazopanib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HMGN3_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
APLNR	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00488344
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MT-01A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
membrane	GO Cellular Component Annotations 2015	1.0	null
YY1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_choroid plexus epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_neural cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K58149231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.06506
BRD-K29242326	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.1789
MCF7_Mocetinostat_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.00812201
hsa-miR-525-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
POLR2A_A549_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-GF-A2C7-01A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SP1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Gene_Name_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_HepG2_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
PSMD11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.00219
BRD-K72681425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65324
GTEX-RVPU-0011-R5A-SM-2XCAD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.29735
GSE178255_2_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PRR11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.14658
BRD-K29543978	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47213
GSE235701,GSE261434_2_v_3_enasidenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GR-M	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898209
VZ in rostral cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.20351
PMC9019027-42003_2022_3332_MOESM3_ESM.xls-Table_S1_HUVEC_MED23-KD_DEGs-gene_id_AR	Rummagene Transcription Factor Associations 2026	1.0	null
lateral ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.0604
oxantel-1277	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-A47109850	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.50178
GTEX-S4Z8-0126-SM-4GICC	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46023
H3K27ac_MCF-7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE102505_4_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_2625_KO_AIB1_SRP282647	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-16.5459
CTCF_Caco-2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-RU72-0011-R5A-SM-2TF6U	GTEx Tissue Sample Gene Expression Profiles	1.0	1.2953
RASSF4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.16024
FOS_MCF 10A_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWCY-0005-SM-33HBP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.23849
ME-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.84045
MAFF	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.0975
H3K4me3_fibroblast of lung_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K54233340_Dorsomorphin dihydrochloride_SKM1_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me1_megakaryocyte_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE202434,GSE202438_2_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WHSE-0011-R1A-SM-3P5ZK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.1904
MTG1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.23529
H2BC4	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30228
EGR1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE169155_5_v_4_acetaminophen_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-TSE9-0011-R5A-SM-3DB7J	GTEx Tissue Sample Gene Expression Profiles	1.0	1.3433
MARS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00550818
mRNA_ZSCAN4C_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE132759_4_v_0_fgfr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4PP-1026-SM-3NM9O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.877639
superficial dorsofrontal area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.04578
GSE164874_5_v_4_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PLZ5-0006-SM-2S1NZ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.08945
NFYB	ENCODE Transcription Factor Targets	1.0	null
BRD-K08311368	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.12287
Heart - Left Ventricle	GTEx Tissue Gene Expression Profiles 2023	1.0	2.86413
TBP_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE174418,GSE174421_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
diethylstilbestrol_mus musculus_gpl6887_gse37969	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K72145393	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36824
POLR2A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of ion transmembrane transporter activity	GO Biological Process Annotations 2015	1.0	null
PMC11265019-13048_2024_1474_MOESM4_ESM.docx-0-ZHX3_ZHX3	Rummagene Transcription Factor Associations 2026	1.0	null
mantle zone of cerebellar vermis	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.12284
SET-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.914589
GSE221327_10_v_11_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-S7SE-0011-R10A-SM-2XCDF	GTEx Tissue Sample Gene Expression Profiles	1.0	1.16072
Head and Neck squamous cell carcinoma_HNSC_TCGA-D6-6517-01A-11R-1873-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
posterior (caudal) superior temporal cortex (area 22c)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.08126
GTEX-WQUQ-0006-SM-3MJF4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09505
GSE123734_1_v_0_mien1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE217776,GSE217829_2_v_6_sgf29_human	RummaGEO Gene Perturbation Signatures	1.0	null
Whole Blood	GTEx Tissue Gene Expression Profiles 2023	1.0	3.27164
GSE127790_11_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Lymph node cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.318
GTEX-RU1J-0006-SM-2TF6M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47933
GTEX-XQ3S-0426-SM-4BOOA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.895787
POLR2A_olfactory bulb_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS5_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-526b	TargetScan Predicted Conserved microRNA Targets	1.0	0.404082
TAF11	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.12721
hsa-miR-4419b	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
CTCF_fibroblast of villous mesenchyme_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TNFSF9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00593514
BRD-K78904317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.08065
BRD-K68301602	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.33644
GTEX-XUZC-1726-SM-4BRWS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86543
BRD-K50511447	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.46427
primary auditory cortex (core)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.17343
NEDD4L	Pathway Commons Protein-Protein Interactions	1.0	null
GIGYF2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00445007
BCLAF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A10523515_GSK-429286A_HA1E_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K48020855	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13596
Lung squamous cell carcinoma_LUSC_TCGA-34-5928-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93534327	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.28126
GSE114232_8_v_6_mavs_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-XOTO-0006-SM-4B64T	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47929
DRGX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.8092
layer 3 of LOT	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16155
PL18	COSMIC Cell Line Gene CNV Profiles	1.0	2.09117
CRCGN015_MCF10A_48H:J16	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-4.0593
MCF7_PD173074_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0199089
GTEX-RU1J-0326-SM-46MUM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.839658
K562_AZ 960_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0131359
GTEX-R55E-0006-SM-2TC5G	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.978404
IMR-32	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.926404
VZ in medial temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.05665
regulation of anion channel activity	GO Biological Process Annotations 2023	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-6407-01A-13R-1708-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE122509,GSE122513_3_v_0_ibrutinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-O5YV-0006-SM-2I5GX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.09739
GSE122215,GSE122217_0_v_4_peg10_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
reuniens nucleus, main part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22695
H3K9ac_NT2-D1_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ECHDC1	Pathway Commons Protein-Protein Interactions	1.0	null
Lung adenocarcinoma_LUAD_TCGA-49-6745-01A-11R-1858-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SIRT1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.03279
TAF1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
corpus callosum	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3951
GTEX-U8T8-0005-SM-3DB8F	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.08351
striatum_12 pcw_F_12960	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.68396
BRD-K17210248_S1216_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
HA-E2F1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K01212001	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01544
IGSF1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00603568
MAZ_IMR-90_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
USF2	ENCODE Transcription Factor Targets	1.0	null
BRD-K95213130	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.14609
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-2cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
hsa-miR-4774-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
Bladder Urothelial Carcinoma_BLCA_TCGA-G2-A3VY-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE193588_1_v_0_pax3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K24418561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.04174
superficial stratum of r8BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6724
CHD1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_foreskin fibroblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H2AFZ_astrocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ELK1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amygdaloid complex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.883848
RBBP5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_small intestine_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HA1E	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.86
NNT	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00292812
GSE233183,GSE233187_2_v_9_larp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NCI-H2170	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.898209
POLR2AphosphoS2_myocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-CC-5258-01A-01R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE182680,GSE182683_10_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
MID1IP1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.27669
CL-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.826816
BB65-RCC	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-1.92119
yy2_20215434_hela_lof_human_gpl570_gds3788	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.008582
CTCF_A549_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE157036,GSE166411_3_v_1_halofuginone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE192870_2_v_3_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K21680192_mitoxantrone_MDAMB231_3_h_0.12_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K41719231	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.37338
GSE101336_1_v_0_decitabine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H441	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.0164
ISX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.2624
BRD-K31843556_-666_ASC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K69585439	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.33159
BRD-A17065207_-666_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CTCF_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_GM12891_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-TSE9-3126-SM-4DXSY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.930773
GSE114258_3_v_2_foxk1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
SK-N-DZ	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.88688
GSE89018_1_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.87379
POLR2A_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_thymus_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-T2IS-0011-R5A-SM-32QP4	GTEx Tissue Sample Gene Expression Profiles	1.0	3.38296
GTEX-U3ZG-0006-SM-47JWX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52136
GSE151090_2_v_3_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
shsy5y	HPA Cell Line Gene Expression Profiles	1.0	2.07932
PMC9537523-41467_2022_33364_MOESM7_ESM.xlsx-scores_wilcoxon_1_MONTH_ORG-EN1_n_EN1	Rummagene Transcription Factor Associations 2026	1.0	null
dorsolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.40979
MDA-MB-330	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.7744
Skin Cutaneous Melanoma_SKCM_TCGA-EE-A2M7-06A-11R-A18U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H2AFZ_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Kidney renal papillary cell carcinoma_KIRP_TCGA-BQ-5891-01A-11R-1592-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
LHX5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.7355
H3K4me1_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
ZNF564	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.63217
GTEX-P44H-2426-SM-2XCEJ	GTEx Tissue Sample Gene Expression Profiles	1.0	0.96067
GTEX-QESD-1626-SM-2S1RB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862866
PMC11098130-pnas.2322688121.sd01.xlsx-NER_Contact_vs_mono-id_NR1H2	Rummagene Transcription Factor Associations 2026	1.0	null
Lung adenocarcinoma_LUAD_TCGA-69-7761-01A-11R-2170-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ZNF24	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	82.9149
POLR2AphosphoS5_HL-60_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
COPI-coated vesicle membrane	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.909
UACC257	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.1952
BRD-K03067624_EMETINE HYDROCHLORIDE_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
PMC5989213-41467_2018_4462_MOESM8_ESM.xlsx-3-Supplementary_Data_3_List_of_2687_genes_differentially_expressed_between_SETBP1-G870S_and_Empty_293_FLP-In_lines_SETBP1	Rummagene Transcription Factor Associations 2026	1.0	null
STAT1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE189789_0_v_1_oridonin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Mesna_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.016227
H3K9ac_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QVJO-0011-R9A-SM-2S1QH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.27518
GSE221327_1_v_9_clpp_human	RummaGEO Gene Perturbation Signatures	-1.0	null
EPI-2399-1 (CTNNBL1)	NURSA Protein Complexes	1.0	null
DPP7	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00555755
GSE179880_10_v_13_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_LNCaP clone FGC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226408_1_v_0_inpp4b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
SIN3A_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ESRRA	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.1478
GTEX-X261-0011-R8A-SM-4E3I5	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828825
H3K9ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of lung_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K91683342	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25377
GSE119978,GSE180930_3_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BACH1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE154577_7_v_9_plagl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
KIF3B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00399787
GSE119978,GSE180930_3_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_SGI-1776 free base_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.020615
BRD-K76015448	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.10258
GTEX-QLQW-0126-SM-447BK	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.843281
GSE157594_6_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
NCI-H82	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
PDE3A	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00570379
GSE95688_1_v_0_glutathione_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SAP30	ENCODE Transcription Factor Targets	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K25045770	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15867
BRCA1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_BJ_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
r9 part of the inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.96
HOP-92	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.942392
GPR17	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00610425
ZNF333	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.64132
4540_LDB1_P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.625998
BRD-K32235162	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.26993
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.38803
H3K4me2_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE198434_1_v_0_aspirin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PHF8_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AH-0005-SM-33HBR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.64658
GSE254649_3_v_1_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X15G-0005-SM-3NMDA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58583
hsa-miR-129-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.07142
Orbital area, ventrolateral part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.09297
Perturb_3925_KD_VPS37C_SRP266781	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.5591
BRD-K68305833	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.31608
CHD2_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X585-0011-R10A-SM-46MUY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.22451
BRD-K74879991	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.43196
GABPA_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H4K20me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Gustatory areas, layer 5	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.27818
GSE128634,GSE128636_1_v_3_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE149123,GSE149128_1_v_0_cdk7_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
laterodorsal part of putamen	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.75516
ATXN1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.38542
Perturb_14971_KD_Crebbp_SRP154933	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	2.73165
GTEX-WI4N-1026-SM-3LK7N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.896462
Crus 2, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.55444
YY1_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_fibroblast of pedal digit skin_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
icSARA deltaORF6_7Hour_23365422_GSE33267	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.40235
PHLDB2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00608658
BRD-K34519313	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24765
MCF7_CUDC-101_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0107761
GSE217405_0_v_2_osimertinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC5452392-13058_2017_854_MOESM3_ESM.xlsx-Table_S7-Variants_within_GWAS_blocks_control_MAF_0_01_case_MAF_control_MAF_within_gwas_breast_cancer_regions_deleteious_score_0_5_MAF	Rummagene Transcription Factor Associations 2026	1.0	null
berberine-1778	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
nes	HPA Cell Line Gene Expression Profiles	1.0	0.962247
HUH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	2.44249
GSE197117_0_v_1_kdm6b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE178340_7_v_4_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
isthmic liminal part of the periaqueductal gray	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.03439
factors	GeneRIF Biological Term Annotations	1.0	null
SRY	ChEA Transcription Factor Targets	1.0	null
H3K4me3_GM12878_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Bed nuclei of the stria terminalis, anterior division, fusiform nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.15349
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95802
plasma membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
CTCF_SK-N-SH_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ5-0326-SM-3P614	GTEx Tissue Sample Gene Expression Profiles	1.0	1.05008
TFAP2C	ENCODE Transcription Factor Targets	1.0	null
HDAC2	ENCODE Transcription Factor Targets	1.0	null
Squamous cell carcinoma of lung_Lung Tissue_GSE3268	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.49025
H3K4me3_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE212848_1_v_0_pum1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K33767317	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7709
GSE147876,GSE147877_2_v_8_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
U251MG	DepMap CRISPR Gene Dependency	1.0	2.23486
SOX9	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	21.9211
positive regulation of cellular component organization	GO Biological Process Annotations 2015	1.0	null
PBX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.5556
hippocampus (hippocampal formation)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.73685
GSE120413,GSE120447_3_v_5_bap1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me1_Skeletal Muscle	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
BRD-K17367110	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.66741
CTCF_MCF-7_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11003700-pbio.3002240.s013.xlsx-siMYCN_RNA_IMR32_48h_q_0_05_1_5-Table_S6_Genes_commonly_and_differentially_regulated_by_MYCN_and_WDR5_in_IMR32_cells_MYCN	Rummagene Transcription Factor Associations 2026	1.0	null
TEAD4_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
WIPI2	Pathway Commons Protein-Protein Interactions	1.0	null
PFEIFFER	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.50224
USF1	JASPAR Predicted Transcription Factor Targets	1.0	null
H3K4me3_erythroblast_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-P4QS-0008-SM-48TDY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.887456
EC-GI-10	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	3.35284
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_2_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
GSE228181_4_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K06719105	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14313
YY1_SK-N-SH_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TIAM2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0068205
anterior (rostral) cingulate (medial prefrontal) cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.3531
HCC1806	CCLE Cell Line Gene CNV Profiles	-1.0	-1.63087
CTCF_GM12866_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
L3MBTL3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00559338
adrenal_4c	HPA Tissue Sample Gene Expression Profiles	1.0	1.01475
SG in rostral perirhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.897774
NFAT5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00679491
GSE162087_0_v_1_dexamethasone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ATG3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06055
GTEX-SUCS-0006-SM-4DM59	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.58784
Nucleus of the lateral olfactory tract, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.12266
GSE154464_1_v_2_cdk6_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE111247_2_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
UBTF	ENCODE Transcription Factor Targets	1.0	null
GSE100316_3_v_4_mtor_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-X5EB-0008-SM-46MU3	GTEx Tissue Sample Gene Expression Profiles	1.0	1.13615
RAD21_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EB-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95802
CME1	DepMap CRISPR Gene Dependency	1.0	2.95938
GTEX-XOTO-0011-R3A-SM-4B64W	GTEx Tissue Sample Gene Expression Profiles	1.0	0.849672
H3K4me3_osteoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X4LF-0006-SM-3NMCO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.34089
GTEX-XUJ4-0126-SM-4BOP7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.06381
HEC6_ENDOMETRIUM	CCLE Cell Line Proteomics	1.0	2.18144
GSE171837_0_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
Perturb_13467_Mut_Ar_SRP045727	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	16.1005
GSE137653_2_v_3_siglecf_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Purkinje cell layer of CbHCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.41676
trovafloxacin_homo sapiens_gpl96_gse9166	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PRRX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.3233
hsa-miR-3662	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
POLR2AphosphoS5_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_GM06990_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K54836449	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.36485
A498	BioGPS Cell Line Gene Expression Profiles	1.0	0.895541
BRD-K09248459	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.45997
KDM5B	ENCODE Transcription Factor Targets	1.0	null
transport	GO Biological Process Annotations 2015	1.0	null
GTEX-PWOO-0326-SM-48TDB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19704
GTEX-SJXC-2026-SM-4DM6N	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01072
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_3_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
GSE149359_2_v_0_asap2_human	RummaGEO Gene Perturbation Signatures	1.0	null
FOXO3	ChEA Transcription Factor Targets	1.0	null
GSE131649_2_v_3_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
P63_DEPLETION_GDS2534_63_human_ME180 cervical carcinoma cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GSE135030_3_v_0_fludarabine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_LNCaP clone FGC_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE230744,GSE237803_5_v_2_hira_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158834_7_v_6_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-PVOW-0011-R5A-SM-32PL7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81371
Brain Lower Grade Glioma_LGG_TCGA-HT-A74L-01A-11R-A32Q-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Buspirone-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
HCC38	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.33486
GSE182179_0_v_3_kdsr_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Dorsal peduncular area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78379
POLR2AphosphoS5_PFSK-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4507	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
H3K4me3_CD14-positive monocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE176093_0_v_1_mineral oil_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE171724_1_v_6_ezh2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE110440_2_v_0_rad21_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
STAT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0132
H3K27ac_testis_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
HNF1A_OE_GDS1499_252_human_HEK293 embryonic kidney cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	null
H3K4me3_fibroblast of lung_hg19_5	ENCODE Histone Modification Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7013-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE160304,GSE163392_4_v_3_zswim8_human	RummaGEO Gene Perturbation Signatures	1.0	null
central glial substance	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.70979
BRD-K94697940	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.34108
PMC9013128-NIHMS1795992-supplement-6.xlsx-ARID2_MUT_Upregulated-Gene_name_ARID2	Rummagene Transcription Factor Associations 2026	1.0	null
POLR2A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F1	JASPAR Predicted Transcription Factor Targets	1.0	null
Crus 1, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.90656
H3K27ac_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-PSDG-1526-SM-48TCY	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.862286
hsa-miR-3135b	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
BRD-K73692505	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.0547
GTEX-R53T-1626-SM-3GAEW	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861675
GSE178340_1_v_4_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CTCF_H54_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_WI38_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-HC-7736-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
4150_INTS5_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.712106
GSE201877_1_v_0_yap1_human	RummaGEO Gene Perturbation Signatures	1.0	null
CTCF_GM12865_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4277	TargetScan Predicted Conserved microRNA Targets	1.0	0.598666
MCF7_Alendronate sodium trihydrate_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0221654
BCL3_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_iPS DF 19.11	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
9398_TTI1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.603039
GTEX-XQ8I-0626-SM-4BOPT	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.858415
Perturb_12664_KD_SLNCR_SRP151199	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.80748
GSE121319_1_v_0_gprc5a_human	RummaGEO Gene Perturbation Signatures	1.0	null
BCLAF1	ENCODE Transcription Factor Targets	1.0	null
HDAC2_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
IKZF3	Pathway Commons Protein-Protein Interactions	1.0	null
ALOX5	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00482142
GSE211128_9_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-X585-0008-SM-46MU4	GTEx Tissue Sample Gene Expression Profiles	1.0	0.825552
BRD-K14645917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.788
GSE148692,GSE148695_2_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-T6MN-0011-R7A-SM-32QP5	GTEx Tissue Sample Gene Expression Profiles	1.0	2.1866
POLR2AphosphoS5_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K12057390_APIGENIN TRIACETATE_HA1E_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
SUM 52PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.04554
bed nucleus of stria terminalis, lateral amygdaloid division	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.14548
positive regulation of intracellular protein transport	GO Biological Process Annotations 2015	1.0	null
GSE102505_6_v_3_tunicamycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MCF7_Divalproex Sodium_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0163778
HDAC2_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE171175,GSE171181_1_v_2_e7107_human	RummaGEO Drug Perturbation Signatures	1.0	null
hydrocortisone_homo sapiens_keloid scar_gds3071	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
choroid plexus of the fourth ventricle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.98067
GSE147662_2_v_4_nicotinamide_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K71631414	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.68222
GTEX-NPJ8-0011-R6a-SM-2HMKB	GTEx Tissue Sample Gene Expression Profiles	1.0	2.55903
GTEX-N7MT-0011-R7a-SM-2I3FZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.78186
GSC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0025
TBK1.DF	MSigDB Signatures of Differentially Expressed Genes for Cancer Gene Perturbations	-1.0	null
VIIIA, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.26739
GSE178340_7_v_9_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
7608_RUVBL2_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.540625
GTEX-VUSG-1426-SM-3GIJN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.25822
GTEX-P4QR-0006-SM-2I5GN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.20525
COPI vesicle coat	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	0.912
GSE137144_2_v_1_nlrp3_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE148066,GSE157787_2_v_1_n4bp1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_H7_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
DNAJB1	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2A_GM12891_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Fedratinib_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0159613
PMC9377669-tx1c00392_si_002.xlsx-1160_PS-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GSE151689_0_v_1_panobinostat_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961868
BRD-K28360340_TW 37_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
RAD21	ENCODE Transcription Factor Targets	1.0	null
ChIP_KLF4_19030024	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
CTCF_GM19240_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE133516_0_v_3_kat7_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE248045,GSE248046_0_v_5_runx1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_CD4+ CD25int CD127+ Tmem Primary Cells	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-2871-03A-01T-0735-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K78126613_MENADIONE_RKO_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE147056_2_v_1_actl6b_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
A549_Tozasertib_10nM_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0122521
paracentral lobule, posterior part, left, lateral bank of gyrus	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.26883
Mesothelioma_MESO_TCGA-MQ-A4LP-01A-11R-A34F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE145171_0_v_1_prox1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K33379484	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.34991
GSE182680,GSE182683_5_v_6_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AFZ_B cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative regulation of cell motility	GO Biological Process Annotations 2025	1.0	null
medial amygdala, anterodorsal part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.49896
CEBPD_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE93309_2_v_4_prmt1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE228181_3_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-BA-5153-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K11715561	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10312
anterior (rostral) cingulate (medial prefrontal) cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.845364
GTEX-XUJ4-0005-SM-4BOQ6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.49065
GSE125014_6_v_4_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XMD1-0011-R6A-SM-4AT5K	GTEx Tissue Sample Gene Expression Profiles	1.0	1.81894
GSE230573_1_v_0_dcaf1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE171401_1_v_0_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-OHPM-0006-SM-2HMKU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.0321
GSE196259_2_v_3_gcm1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ7-0011-R6a-SM-2I3G7	GTEx Tissue Sample Gene Expression Profiles	1.0	2.56107
GSE153867_6_v_3_olaparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
ventrolateral prefrontal cortex_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.73444
posteromedial visual area, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.63055
BRD-K45282766	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.44431
K562_Mesna_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0203562
GSE218580_1_v_0_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K81528515_nilotinib_BT20_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
nucleus coeruleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.03341
GSE152441,GSE152442_6_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-X585-0005-SM-46MV3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.06494
JUN_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_Pirarubicin_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0176816
H3K4me3_SK-N-MC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE208171_0_v_1_zc4h2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC4944136-srep28995-s2.xls-ARGFX-gene_ARGFX	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K21678546	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.67232
negative regulation of cellular component movement	GO Biological Process Annotations 2015	1.0	null
TMC8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00509056
GSE183113_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HAND2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	20.6691
GSE95386_0_v_1_trim24_human	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-8cell_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
1-EBIO	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.61081
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-C5-A8YT-01A-11R-A37O-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE233679_6_v_10_nicotinamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
VAESBJ	DepMap CRISPR Gene Dependency	1.0	3.36655
posteroventral (inferior) parietal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.73752
BRD-K37456065_VU0365114-2_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
FOS_MCF 10A_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TBP_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K72310865	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10563
VPS18	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47307
amylocaine-1991	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
locus ceruleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.83761
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.129
GSE254649_2_v_1_cstf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_choroid plexus epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IFNA8	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00544603
H3K4me3_cardiac mesoderm_hg19_8	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QLQW-0226-SM-447BJ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.01854
BRD-K63912037	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.00383
dorsolateral prefrontal cortex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.75177
BRD-K40300525	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.077
H3K4me3_cardiac muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Spleen	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.00587
modulate	GeneRIF Biological Term Annotations	1.0	null
BRD-K83715372	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.43068
GSE242199_9_v_0_ntrk2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE152441,GSE152442_7_v_3_folic acid_human	RummaGEO Drug Perturbation Signatures	1.0	null
hsa-miR-4528	TargetScan Predicted Conserved microRNA Targets	1.0	0.226173
COX7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.85746
JHOC5	CCLE Cell Line Gene CNV Profiles	-1.0	-2.00588
Taenia tecta, dorsal part, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.20987
LIVF001-021	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.53469
BRD-K34501072	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03769
layer IIIa of caudal entorhinal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.58914
hsa-miR-378a-5p	MiRTarBase microRNA Targets	1.0	null
Skin Cutaneous Melanoma_SKCM_TCGA-FS-A1ZD-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Pancreatic adenocarcinoma_PAAD_TCGA-IB-7893-01A-11R-2204-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE180200,GSE180201_2_v_9_qpctl_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-RNOR-2426-SM-48FDY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.837271
GSE159446,GSE159449_1_v_0_tunicamycin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
RAD21_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NEK11	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00490674
496100514_FWM_no dementia_TBI_95-99_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.16537
ICOSLG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0076925
hsa-miR-576-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
hsa-miR-885-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.49473
BATF	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00587428
BRD-K48113109	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03488
GSE182680,GSE182683_5_v_11_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_HL-60_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SUM 1315M02	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.872663
ZNF217	ENCODE Transcription Factor Targets	1.0	null
H3K27me3_G1E-ER4_mm9_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE221020,GSE221023_2_v_0_pten_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HEP G2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.52724
GSE193993_1_v_2_sstr2_human	RummaGEO Gene Perturbation Signatures	1.0	null
STAT3_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TEAD4_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
JUND	ENCODE Transcription Factor Targets	1.0	null
MCF7_Anacardic Acid_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0136747
HCC1319	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.856636
COLO205	BioGPS Cell Line Gene Expression Profiles	-1.0	-0.942259
CTCF_GM12878_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148692,GSE148695_2_v_3_satb2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
PMC8763317-MO-018-D1MO00236H-s002.xlsx-PHF21A_S0_1-Gene_names_PHF21A	Rummagene Transcription Factor Associations 2026	1.0	null
GSE164874_5_v_6_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Liver	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MCF7_M344_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0119976
H3K4me2_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
POLR2AphosphoS5_SK-N-MC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MEWO	COSMIC Cell Line Gene Mutation Profiles	1.0	null
BRD-K77281588	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31784
GSE217156_1_v_3_trpc1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE110268_1_v_3_foxd1_human	RummaGEO Gene Perturbation Signatures	1.0	null
ZR7530	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	-1.0	-0.950757
GSE112860_3_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Endocrine gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
MCF7_AC480_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0126802
KO52	CCLE Cell Line Gene CNV Profiles	-1.0	-1.6498
FOS_MCF 10A_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ATF2	ENCODE Transcription Factor Targets	1.0	null
GSE182680,GSE182683_10_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
inferolateral temporal cortex (area TEv, area 20)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.05618
GSE116810_2_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	1.0	null
G96	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.18441
GSE210101,GSE210114_2_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
inner SZ in dorsolateral prefrontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-0.892597
CW-2	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CTCF_astrocyte of the cerebellum_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
letrozole-2916	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CTCF_pancreas_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-OHPL-0006-SM-3MJHB	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.63725
GSE233647_2_v_0_docetaxel_human	RummaGEO Drug Perturbation Signatures	-1.0	null
K562_JQ1_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0154544
A549_SRT2104_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0169226
zona incerta, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-0.913351
cortex of cerebellar hemisphere	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.40319
GSE193993_0_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
intermediate stratum of APal	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24382
POLR2AphosphoS5_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral part of VMH	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.06338
GTEX-QLQW-0326-SM-447A8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.86964
BRD-K01377768	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	5.09247
GSE173911,GSE173917_0_v_1_morc3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
H3K4me3_Jurkat_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
brain	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
A-Vietnam-1203_CIP048_RG3-2004(H5N1)mutPB1-F2del_0Hour_None_GSE43203	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.81386
GSE202284,GSE202289_1_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K63787803	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.11523
rosiglitazone_mus musculus_gpl7202_gse19896	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ELF1	ENCODE Transcription Factor Targets	1.0	null
GTEX-SNOS-0006-SM-32PLH	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.53885
GSE171837_0_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
HCC202	CCLE Cell Line Gene CNV Profiles	1.0	1.72344
GTEX-WRHU-1226-SM-4E3IJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.876534
BRD-K32434600	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.50883
hsa-miR-520a-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.293524
Male reproductive organ cancer	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.15
H3K4me3_skeletal muscle cell_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_7	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2AphosphoS2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SIU8-0006-SM-2XCE5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00983
Kidney renal clear cell carcinoma_KIRC_TCGA-CJ-6028-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K37865504_LY 2183240_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE234340_1_v_7_muc2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-U4B1-0126-SM-4DXSN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20361
GSE211474,GSE212779_0_v_1_phf8_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K95007662	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.19236
GABPA	ENCODE Transcription Factor Targets	1.0	null
GSE111247_14_v_6_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_7279_KD_HS51/NRSE_SRP261089	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-2.33613
KDM1A_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NR2F2	ENCODE Transcription Factor Targets	1.0	null
CTCF_fibroblast of mammary gland_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPB_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
superficial stratum of r5BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.543
MYC	ENCODE Transcription Factor Targets	1.0	null
GSE171837_1_v_2_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me1_Brain Mid Frontal Lobe	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
midbrain reticular formation, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.829126
POLR2A_GM18505_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F6	ENCODE Transcription Factor Targets	1.0	null
GSE135514_8_v_3_dasatinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
posterior (caudal) superior temporal cortex (area 22c)_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.1157
GSE223609,GSE223610_0_v_2_kdm6a_human	RummaGEO Gene Perturbation Signatures	1.0	null
ARID3A_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SK-MEL-31	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12542
PMC12500496-262_2025_4178_MOESM2_ESM.xlsx-THP1_enriched_for_CVGBM-gene_name_GLI2	Rummagene Transcription Factor Associations 2026	1.0	null
MAX_NB4_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MCF7_AC480_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0142064
GTEX-UJMC-0005-SM-3GACU	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.54758
hsa-miR-3124-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.072324
BRD-K35517098	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01413
BRD-K10846167_N-((1H-naphtho[2,3-d]imidazol-2-yl)methyl)-2-morpholino-9-(thiophen-3-yl)-9H-purin-6-amine_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE95077_5_v_0_amiloride_human	RummaGEO Drug Perturbation Signatures	1.0	null
PMC9108619-EMBJ-41-e109191-s016.xlsx-UPF3A_KO_14_3B_KD-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Gestational trophoblastic neoplasm	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.21
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.03082
GTEX-T6MN-2726-SM-4DM77	GTEx Tissue Sample Gene Expression Profiles	1.0	0.828144
STAT3	ChEA Transcription Factor Targets	1.0	null
NCIH322	CCLE Cell Line Gene CNV Profiles	-1.0	-1.53897
GSE128232,GSE128233_1_v_0_phf2_human	RummaGEO Gene Perturbation Signatures	1.0	null
SKCO1	CCLE Cell Line Gene CNV Profiles	1.0	1.50206
BRD-K53308623	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.21762
PMC6815046-13073_2019_678_MOESM2_ESM.xlsx-TCF20-Unnamed_0_TCF20	Rummagene Transcription Factor Associations 2026	1.0	null
IKBKG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00483875
GSE193282_2_v_0_cd44_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_olfactory bulb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
SETDB1	ENCODE Transcription Factor Targets	1.0	null
Nkx3-2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	19.5573
lateral ganglionic eminence_8 pcw_M_13058	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.839045
SHSYSY-RA	BioGPS Cell Line Gene Expression Profiles	1.0	2.4122
paraventricular nucleus of the hypothalamus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	0.854364
Sarcoma_SARC_TCGA-X6-A8C7-01A-11R-A36F-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
8288_SOX2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.585801
Culmen	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.08623
DMS-114	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-2.82679
GTEX-XXEK-0005-SM-4BRWJ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.36029
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.21028
BRD-K23363278_CYT997_A673_6.0_h_1.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
CHD7_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SEPHS2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00640323
CEL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.0687
GTEX-S7SE-0011-R11A-SM-2XCDD	GTEx Tissue Sample Gene Expression Profiles	1.0	0.907851
BRD-K08219814	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24844
RKO	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
central nuclear group	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	2.18457
GSE225869_3_v_0_temozolomide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-3929	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
EME2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.04029
GTEX-XPVG-2526-SM-4B66D	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.875952
CTCF_H1-hESC_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF7	ENCODE Transcription Factor Targets	1.0	null
regulation of protein targeting	GO Biological Process Annotations 2015	1.0	null
TCF3-18347094-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F6-01A-11R-A10U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67319345	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.60245
GSE130081,GSE130082_5_v_10_neil2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A13122391_16-HYDROXYTRIPTOLIDE_SW620_6.0_h_0.08_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GATA3_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V1D1-0226-SM-4JBHG	GTEx Tissue Sample Gene Expression Profiles	1.0	0.852474
NFIX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	36.4548
GSPT1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00583188
GSE197564,GSE198513_2_v_0_mettl3_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
hsa-miR-4753-3p	TargetScan Predicted Conserved microRNA Targets	1.0	0.131849
GSE169356_0_v_3_ivermectin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BT483	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.717314
Taenia tecta, dorsal part, layer 2	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.43833
EGR1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-66-2790-01A-01R-0980-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-3613-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
EGR1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-X88G-0006-SM-47JX5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.40357
BRD-K47869605_PODOFILOX_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE131161_2_v_4_rarres1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
TBX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	41.1973
KHM-1B	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.87236
Perturb_1613_KO_Gpr174_SRP365825	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-5.45895
GSE180200,GSE180201_15_v_11_qpctl_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
Retrosplenial area, lateral agranular part, layer 2/3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.05619
RUNX3_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K61416283	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.25506
intermediate stratum of AStr	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.41848
GSE218819_3_v_4_kdm5b_human	RummaGEO Gene Perturbation Signatures	-1.0	null
tissues, cell types and enzyme sources	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
r8 part of inferior olive	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.3638
GSE95688_7_v_5_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
RACK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.37021
BRD-K74727418	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.10566
Medial amygdalar nucleus, anteroventral part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.39705
H3K4me3_GM12866_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_mammary epithelial cell_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPARG	JASPAR Predicted Transcription Factor Targets	1.0	null
head	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	0.766457
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.977954
GSE233049_2_v_0_atf3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
primary motor cortex (area M1, area 4)_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.920185
GSE195568_3_v_7_palbociclib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE239844_7_v_10_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Curcumin_1然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0146848
r7 part of parapyramidal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76551
posteromedial visual area, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.5188
H3K4me3_BE2C_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me2_H1-hESC_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SKRC20	DepMap CRISPR Gene Dependency	1.0	2.32102
regulation of cellular protein localization	GO Biological Process Annotations 2015	1.0	null
GSE176008_0_v_5_azacitidine_human	RummaGEO Drug Perturbation Signatures	1.0	null
K562_AG-490_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143701
superficial stratum of r4BI	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33992
MOGGCCM	CCLE Cell Line Gene CNV Profiles	1.0	1.39561
H3K4me3_kidney epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
positive regulation of cellular process	GO Biological Process Annotations 2015	1.0	null
CBX3	ENCODE Transcription Factor Targets	1.0	null
hsa-miR-4274	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
RCOR1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-E1-5302-01A-01R-1470-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7784-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
hsa-miR-889	TargetScan Predicted Conserved microRNA Targets	1.0	0.003282
GTEX-OOBK-0005-SM-2YUMG	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.84496
IRF1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PIP4K2B	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00360902
SYMPK	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.75388
GSE201309_1_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC8160578-JCB_202009147_TableS4.xlsx-E2F1_targets-Genes_n_1867_E2F1	Rummagene Transcription Factor Associations 2026	1.0	null
primary visual cortex (striate cortex, area V1/17)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0587
PMC13187244-41392_2026_2766_MOESM2_ESM.xlsx-Table_S17-Table_S17_Differentially_expressed_genes_in_OCI-AML3_cells_ZMIZ1_inhibitor_SIH-001_4E_vs_DMSO_RUNX2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K27ac_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE173810_0_v_3_igf2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE220097_4_v_1_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4856960-supp_gkv1471_nar-01762-z-2015-File010.xls-Genes_5kb_E2F7_Hyp-gene_name_E2F7	Rummagene Transcription Factor Associations 2026	1.0	null
GSE127916_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXP1_FOXP1	Rummagene Transcription Factor Associations 2026	1.0	null
CD300E	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00515754
OV56	CCLE Cell Line Gene CNV Profiles	-1.0	-1.52569
16151515-TableS2	GeneSigDB Published Gene Signatures	1.0	null
GSE149901_3_v_0_anlotinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
LIN7B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24007
GSE88819_3_v_12_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
cerebellar cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0461
GSE158715_2_v_4_cyp1b1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-R55G-0006-SM-2TC6O	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.59616
SNU-175	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE138019_3_v_6_nudt12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE146687_2_v_0_eribulin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TAF1_GM12892_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTSG	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00512616
GTEX-XLM4-0011-R7A-SM-4AT5L	GTEx Tissue Sample Gene Expression Profiles	1.0	2.07322
MYC_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
mRNA_SOX2_19796622	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
GSE226249_0_v_3_pirfenidone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-XMK1-0226-SM-4B65D	GTEx Tissue Sample Gene Expression Profiles	1.0	1.60416
PMC12619835-41467_2025_66007_MOESM8_ESM.xlsx-Classical_KLF5_peaks-Nearest_Ensembl_1_KLF5	Rummagene Transcription Factor Associations 2026	1.0	null
regulation of anion transport	GO Biological Process Annotations 2015	1.0	null
BICR 78	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.0483
GSE142210_11_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
ELF1_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210580_0_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE201309_4_v_6_matrine_human	RummaGEO Drug Perturbation Signatures	1.0	null
NAE1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.16516
Kidney renal papillary cell carcinoma_KIRP_TCGA-IZ-8196-01A-11R-2404-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Ansiform lobule	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.76405
EGR1_MCF-7_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151412_2_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_fibroblast of lung_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SUM 229PE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-2.14425
GSE131649_6_v_8_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung adenocarcinoma_LUAD_TCGA-55-7283-01A-11R-2039-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-K1-A42X-02A-11R-A24X-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-OXRO-0006-SM-2I5EM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.80315
HUH-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.33729
RFX5_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WHSE-0006-SM-3NMBW	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.70989
PLAU	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00570631
GATA3_T47D_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me1_brown adipose tissue_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
WDCP	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.10759
GTEX-WZTO-0011-R11A-SM-4E3K9	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909262
Edinger-Westphal nucleus (accessory oculomotor nucleus)	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.985083
GTEX-PX3G-0006-SM-33HBQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00665
GTEX-OXRL-0005-SM-3LK6A	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31733
LMSU_STOMACH	CCLE Cell Line Proteomics	1.0	3.01279
BRD-K34604637	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.27267
GTEX-QLQ7-0005-SM-2S1QP	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.35867
pargyline-1418	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Thalidomide-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-WEY5-0008-SM-4LMKC	GTEx Tissue Sample Gene Expression Profiles	1.0	0.873996
GTEX-UJHI-0008-SM-4IHL1	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03389
H2AFZ_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-ICM_JUN-Unnamed_1_JUN	Rummagene Transcription Factor Associations 2026	1.0	null
PBX3_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE70935_2_v_4_cyfip1_human	RummaGEO Gene Perturbation Signatures	1.0	null
MAZ_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K14098658	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-5.35841
GSE201309_1_v_8_matrine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S7SE-0005-SM-2XCEA	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.975245
primary motor-sensory cortex (samples)_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.977569
BRD-K53903639_480743.cdx_EFO27_6.0_h_80.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-WYBS-1226-SM-3NM9N	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.916683
Lobule III, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.00178
GSE89018_11_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-N7MS-0011-R1a-SM-2HMJG	GTEx Tissue Sample Gene Expression Profiles	1.0	1.07073
GSE107505_1_v_2_nanog_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
COLO 853	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	2.16693
GTEX-N7MS-0011-R5a-SM-2HMK8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.41819
Piriform-amygdalar area, pyramidal layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16493
GTEX-TSE9-0011-R6A-SM-3DB7L	GTEx Tissue Sample Gene Expression Profiles	1.0	1.72
regulation of intracellular transport	GO Biological Process Annotations 2015	1.0	null
H3K4me2_A549_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
IRF1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.96007
TH	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00702364
hsa-miR-629	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.99187
fluphenazine-2697	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
PRPF38B	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.93729
GSE103068_0_v_4_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-XQ8I-0006-SM-4BOQ5	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.50449
Adenoma_Adrenal gland_GSE8514	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-1.7506
CTCF_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HSF2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.0827
H3K4me3_epithelial cell of esophagus_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QMR6-0011-R10A-SM-32PKO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.55022
9680_UTP14A_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.642191
GSE148692,GSE148695_5_v_6_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
ESRRB	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.1542
triamterene-1819	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
RUNX1	ChEA Transcription Factor Targets	1.0	null
GTEX-X4XX-0011-R3B-SM-46MWK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.949561
ZNF384	ENCODE Transcription Factor Targets	1.0	null
GSE94849_1_v_5_pinometostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MFE-319	COSMIC Cell Line Gene Mutation Profiles	1.0	null
H3K4me3_epithelial cell of proximal tubule_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
15958547-SuppTable3	GeneSigDB Published Gene Signatures	1.0	null
FAM204A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.40612
SNU-C5	COSMIC Cell Line Gene CNV Profiles	-1.0	-3.17697
hsa-miR-628-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.32519
AN3-CA	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	1.83433
Subiculum, ventral part, stratum radiatum	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.07788
GSE207611,GSE207612_0_v_1_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
striatum_13 pcw_M_12888	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	2.05929
TUHR4TKB	DepMap CRISPR Gene Dependency	1.0	3.49675
TBP	ENCODE Transcription Factor Targets	1.0	null
H3K4me1_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE180185_9_v_5_setbp1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE143782_3_v_5_calcitriol_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-WFG8-0006-SM-3GIKS	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.56583
GTEX-XAJ8-0006-SM-46MVM	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.59448
NELFE	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.24175
CEBPB_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TET1	ChEA Transcription Factor Targets	1.0	null
BRD-K25236390	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.01976
TCF12_A549_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K56879482	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08741
496100559_FWM_no dementia_no TBI_87_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.11615
GTEX-UTHO-3026-SM-3GAFB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.932517
CSTF1	Pathway Commons Protein-Protein Interactions	1.0	null
metrifonate-1797	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ZC3H3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	3.31037
BRD-A75954196	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.92766
GSE131649_2_v_9_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Barasertib_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0112839
Central amygdalar nucleus, capsular part	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.1004
BRD-A96536816	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.20273
GSE189772,GSE189773_3_v_2_fbxo11_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-A98714080	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.21119
GTEX-WHSE-0011-R7A-SM-3P5YZ	GTEx Tissue Sample Gene Expression Profiles	1.0	1.76952
GTEX-RWS6-0005-SM-2XCAN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.94766
PMC9992472-41467_2023_36735_MOESM5_ESM.xlsx-SOX11_OE_9h_in_SH-EP-Unnamed_7_SOX11	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-XV7Q-0005-SM-4BRWI	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.958475
GTEX-TSE9-0005-SM-4DXUF	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.39752
BRK1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06268
SCC-9	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.2665
Medial amygdalar nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.23528
GSE152432_5_v_2_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE131649_2_v_11_hemin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
r4 part of lateral pontine nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.33992
PMC10319804-41467_2023_38747_MOESM9_ESM.xlsx-KHSRP_KD_genes_up-gene_name_AR	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K77181307	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24974
ventrolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.875056
GSE223893_2_v_9_setd2_human	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of protein targeting to membrane	GO Biological Process Annotations 2015	1.0	null
primary motor cortex (area M1, area 4)_13 pcw_F_12834	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.945485
hsa-miR-548h	TargetScan Predicted Conserved microRNA Targets	1.0	0.714812
Urogenital system	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
cisplatin_homo sapiens_gpl570_gse23553	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-R55D-1426-SM-48FEN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.939344
metformin-1816	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE157904_3_v_1_doxorubicin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Budesonide_AN3 CA	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	-1.0	-0.0190383
K562_JNJ-7706621_10nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0252759
MAX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	16.6038
Folium-tuber vermis (VII)	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.4571
BRD-K36531580	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.11938
KYSE-180	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.854919
striatum_16 pcw_M_12837	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	2.21969
GTEX-OIZI-0005-SM-2XCED	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.00167
tissues, cell types and enzyme sources	TISSUES Experimental Tissue Protein Expression Evidence Scores	1.0	1.53602
GSE152432_6_v_0_zrsr2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE119978,GSE180930_0_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K96740880_NCGC00182608-01_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
CCNT2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K27ac_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SETDB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_3922_KD_VPS37A/VPS37C_SRP266781	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-8.25767
Brain Lower Grade Glioma_LGG_TCGA-HW-7491-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HeLa-S3_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
adrenal gland	GTEx Tissue Gene Expression Profiles	1.0	1.6794
Nfatc2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	29.5412
CAF-1 complex	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.457
molecular layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.10251
adrenal_4a	HPA Tissue Sample Gene Expression Profiles	1.0	0.855333
GSE211128_7_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Pyramus (VIII), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.3518
MSX2	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.6565
GSE231648_0_v_3_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K05041614	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.49353
Paraflocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.16086
POLR2A_heart_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain_Hippocampus_Middle	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	0.971807
Head and Neck squamous cell carcinoma_HNSC_TCGA-CN-4723-01A-01R-1436-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE194396,GSE194429_2_v_3_atrx_human	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K27ac_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_keratinocyte_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
macelignan	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.7767
pipenzolate	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.34467
H3K9ac_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-877-3p	MiRTarBase microRNA Targets	1.0	null
H3K27ac_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-NPJ8-0011-R5a-SM-2HMJY	GTEx Tissue Sample Gene Expression Profiles	1.0	0.901084
RFX5_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_IOX2_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0163951
benzonatate-1801	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
imatinib_homo sapiens_gpl96_gds3044	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
JJN-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.34162
PMC11655728-12672_2024_1562_MOESM2_ESM.xlsx-Sheet1-Hs_ESC_SOX2_targets_Boyer_SOX2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_GM12875_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Perturb_10675_KO_Jmjd6_SRP309362	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-2.62533
BRD-K07996284	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49727
GSE153871_4_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_endothelial cell of umbilical vein_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC7498599-41467_2020_18508_MOESM11_ESM.xlsx-Mor_CTCF-Unnamed_1_CTCF	Rummagene Transcription Factor Associations 2026	1.0	null
HDAC2_H1-hESC_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE143830_0_v_1_trex1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K69580972	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32068
GSE211128_4_v_0_angptl4_human	RummaGEO Gene Perturbation Signatures	1.0	null
NCIH292_LUNG	CCLE Cell Line Proteomics	1.0	3.65599
SU-DHL-10	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.39635
FHL3	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.03106
H3K4me3_fibroblast of skin of abdomen_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-X8HC-0006-SM-46MV6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.12601
GTEX-R55G-2326-SM-2TC61	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.914399
STAT1	ENCODE Transcription Factor Targets	1.0	null
K562_WHI-P154_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0149261
GSE151090_0_v_1_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE120612_4_v_5_etoposide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K4me3_cardiac fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_fibroblast of upper leg skin_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
posteromedial visual area, layer 4	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2185
anterior (rostral) cingulate (medial prefrontal) cortex_37 yrs_M_12303	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.00467
Dorsal peduncular area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.17729
PMC9377669-tx1c00392_si_002.xlsx-9-cis_retinoic_acid-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X4XY-0626-SM-4E3IN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.907422
GSE146612_1_v_3_amiodarone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
6870_PSMD2_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.526556
GSE178340_1_v_6_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
microcellular tegmental nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.78379
CTCF_choroid plexus epithelial cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CP67-MEL	COSMIC Cell Line Gene Mutation Profiles	1.0	null
hsa-miR-3646	TargetScan Predicted Conserved microRNA Targets	1.0	0.766596
Bladder Urothelial Carcinoma_BLCA_TCGA-C4-A0F1-01A-11R-A034-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE142588_2_v_1_cinobufagin_human	RummaGEO Drug Perturbation Signatures	1.0	null
PPARG	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.6418
medial portion of the shell	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.25333
H1_BMP4_Derived_Trophoblast_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.04214
cerebellar cortex_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.870407
ENPP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00474548
Esophagus - Gastroesophageal Junction	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.02744
GTEX-WVLH-0011-R10A-SM-3MJFM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23768
GSE235587_2_v_0_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A549_Tie2 kinase inhibitor_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.013356
GSE210101,GSE210114_5_v_10_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
positive regulation of transport	GO Biological Process Annotations 2015	1.0	null
MAFK	ENCODE Transcription Factor Targets	1.0	null
ChIP_SOX2_18692474	ESCAPE Omics Signatures of Genes and Proteins for Stem Cells	1.0	null
H3K4me3_skeletal muscle myoblast_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me1_mammary epithelial cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_GM20000_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-0011-R7A-SM-3LK7X	GTEx Tissue Sample Gene Expression Profiles	1.0	1.49802
Cervical squamous cell carcinoma and endocervical adenocarcinoma_CESC_TCGA-EA-A3HQ-01A-11R-A213-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_WI38_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7125-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K67442425	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.85881
MDAMB453	DepMap CRISPR Gene Dependency	1.0	3.09214
OCILY3_HAEMATOPOIETIC_AND_LYMPHOID_TISSUE	CCLE Cell Line Proteomics	1.0	2.68683
ARFRP1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00449993
POLR2AphosphoS5_Panc1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEW-0006-SM-4AT4E	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.16466
A-498	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.26109
H3K9ac_HeLa-S3_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A46631350	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.47381
GSE231891_1_v_0_cdk8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD4_Memory_Primary_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	-1.0	-1.10945
GSE128634,GSE128636_4_v_5_foxo1_human	RummaGEO Gene Perturbation Signatures	1.0	null
A549_Tubastatin A HCl_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0201501
BRD-K63250790	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.51916
GSE144838_1_v_8_egfr_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE153871_5_v_3_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
A549_Tie2 kinase inhibitor_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0153983
GSE103068_0_v_7_volasertib_human	RummaGEO Drug Perturbation Signatures	1.0	null
BD-11-DV28_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.264393
TPX2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.06938
hsa-miR-559	TargetScan Predicted Conserved microRNA Targets	1.0	1.26663
BRD-K38750802	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10647
TGM2_KD_GSE23702_713_human_NB4 cells	GEO Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	null
GTEX-UTHO-0011-R5A-SM-3GIJD	GTEx Tissue Sample Gene Expression Profiles	1.0	2.41354
GSE139911_0_v_4_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K79631534	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.48775
GSE173262_6_v_0_ash1l_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K97764662_P2499_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE216273,GSE216292_0_v_8_palbociclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
OV-90	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
CTCF_A549_hg19_10	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H522	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.20324
Perturb_10647_KO_AIB1_SRP282647	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GSE139239_2_v_5_ddr1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
HN	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.05918
Skin Cutaneous Melanoma_SKCM_TCGA-FR-A69P-06A-21R-A311-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
NAMALWA	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.09116
GSE142210_2_v_10_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SP1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU-484	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.06365
periventricular stratum of isBL	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.4688
hippocampus (hippocampal formation)_16 pcw_M_12879	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.886835
Perturb_5153_KD_Dcp1a_SRP014645	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	1.47714
GTEX-OOBJ-1626-SM-2I3F7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.92336
GSE171837_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	1.0	null
hippocampus (hippocampal formation)_40 yrs_F_12304	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.899486
H4K20me1_fibroblast of dermis_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
RCOR1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CD55	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.0067305
CHD2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H2AFZ_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K59671190	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.28523
RELA	ENCODE Transcription Factor Targets	1.0	null
report	GeneRIF Biological Term Annotations	1.0	null
GSE205070_2_v_9_mertk_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_foreskin fibroblast_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
Perturb_1754_KO_Stag2/Runx1_SRP199099	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-20.0
GSE239688_4_v_0_canagliflozin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE158834_2_v_3_palmitic acid_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-X4XX-0011-R6B-SM-46MWP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73657
BRD-K34009761	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.65757
GSE144120_3_v_1_plcg2_human	RummaGEO Gene Perturbation Signatures	1.0	null
GSE218580_1_v_3_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
ART3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00633502
CTCF_GM12871_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
oculomotor nucleus	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.23169
GSE157050,GSE157051_2_v_4_metformin_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE142210_11_v_7_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
hsa-miR-524-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.131849
TCF12_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4646-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
GSE182680,GSE182683_7_v_2_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
Prelimbic area, layer 6a	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.0415
amygdaloid complex_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64223
Lung adenocarcinoma_LUAD_TCGA-75-6207-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ALDH18A1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00523388
Urinary bladder	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.049
K562_XAV-939_100nM_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0155931
PA-TU-8988T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.13187
GSE234637_1_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
Organism form	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
eGFP-JUND_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K73582217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24429
PMC10158025-ijbsv19p2081s6.xlsx-SupTable5-ZBTB20_ZBTB20	Rummagene Transcription Factor Associations 2026	1.0	null
Perturb_8845_KD_PPARGC1B_SRP254908	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
H3K4me3_A549_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
MAX_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-QDT8-0006-SM-32PL3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.945384
Perturb_17240_KO_SRC3_SRP390910	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-1.93392
ventromedial hypothalamic nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.10788
PHOX2A	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	27.1292
SYK_druginhibition_152_GSE34176	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	2.03987
RBIS	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.38232
GSE140937,GSE140938_1_v_2_slfn11_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC6683136-41598_2019_47363_MOESM4_ESM.xlsx-GENE_SET-Positive_correlation_of_ZEB1_and_other_genes_ZEB1	Rummagene Transcription Factor Associations 2026	1.0	null
TFAP2A_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTR9	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.8444
BRD-K25465939	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31873
ZBTB18	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	29.1875
primary motor cortex (area M1, area 4)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.35057
GSE205976,GSE205978_2_v_5_cep83_human	RummaGEO Gene Perturbation Signatures	1.0	null
PMC7857731-elife-63093-supp1.xlsx-DEG_MITF-X6vsEV-SkMEL28-Unnamed_1_MITF	Rummagene Transcription Factor Associations 2026	1.0	null
USF2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
E2F1	ENCODE Transcription Factor Targets	1.0	null
MCF7_SB431542_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0115488
PMC3355086-pgen.1002728.s003.xlsx-Tabelle1-HEY2_upregulated_HEY2	Rummagene Transcription Factor Associations 2026	1.0	null
CTCF_A549_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K23610423	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.24509
negative regulation of cell migration	GO Biological Process Annotations 2015	1.0	null
BRD-K09388706	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.37182
EA-18-FP00_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.268862
GSE235587_2_v_1_mitoxantrone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-P44H-0011-R11A-SM-2XCER	GTEx Tissue Sample Gene Expression Profiles	1.0	1.19448
Head and Neck squamous cell carcinoma_HNSC_TCGA-F7-8298-01A-11R-2403-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE72895,GSE72896_0_v_1_progesterone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-N7MT-0011-R5a-SM-2I3G6	GTEx Tissue Sample Gene Expression Profiles	1.0	1.73054
POLR2A_HepG2_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_HCT116_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11684804-jci-135-174981-s193.xlsx-DESeq2_pseudobulk_AA_Ag_vs_Pre-Gene_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
TEAD4_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-SN8G-0006-SM-32PLD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.32306
H3K4me3_astrocyte of the cerebellum_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE228181_2_v_1_idh1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE130690,GSE130692_2_v_0_sirt6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE184892_4_v_5_trehalose_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H2AFZ_keratinocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventrolateral prefrontal cortex_3 yrs_M_12980	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0576
H3K4me1_mononuclear cell_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hESC_Derived_CD56+_Ectoderm_Cultured_Cells	Roadmap Epigenomics Cell and Tissue Gene Expression Profiles	1.0	1.01156
CTCF_GM12865_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAX_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XBEC-0008-SM-4AT3X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.946637
DARS1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00763701
GSE128333_2_v_1_tcf4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
STIL	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.9808
NOMO1	CCLE Cell Line Gene CNV Profiles	-1.0	-1.43779
MYC_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-0005-SM-4AT4P	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.2206
KMS-34	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	1.12542
Tuberomammillary nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.18929
H3K4me3_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE185163_5_v_2_clic4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE75976_3_v_4_abl1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
r8 part of the paragigantocellular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.66948
1441_CDK7_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.538042
HOXB8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	15.0134
GSE144346_0_v_1_mettl5_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE168797_1_v_6_cannabidiol_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lingula (I), molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.57788
Perturb_9144_KD_METTL3_SRP280216	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	14.7282
PMC12048643-44318_2025_409_MOESM3_ESM.xlsx-regulonTargets-FOXP4_FOXP4	Rummagene Transcription Factor Associations 2026	1.0	null
MCF7_Cyclocytidine HCl_10nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0142797
H3K4me3_GM12878_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GATA5	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.3429
BRD-A94756469_-666_NPC_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
ONECUT1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	26.3642
BRD-K93223696	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.13134
GSE116810_5_v_4_selinexor_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Lung squamous cell carcinoma_LUSC_TCGA-70-6723-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GTEX-R55E-2726-SM-48FCX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.861937
BRD-K47200630	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.15402
GSE218580_1_v_4_fentanyl_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K27ac_keratinocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
496100611_FWM_no dementia_no TBI_84_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.572
mediodorsal nucleus of thalamus_3 yrs_F_12836	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.919636
RUNX3	ENCODE Transcription Factor Targets	1.0	null
GSE160765_2_v_1_twist1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
FOXP2_SK-N-MC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain - Frontal Cortex (BA9)	GTEx Tissue Gene Expression Profiles 2023	-1.0	-1.07722
TET1-21451524-MESC-MOUSE	ChEA Transcription Factor Binding Site Profiles	1.0	null
ZNF143_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H322T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.95795
SARS-CoV MA15_Day7-C57BL-6_None_GSE40824	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-1.11083
CTCF_foreskin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
medial ganglionic eminence_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.63642
GSE216538_7_v_4_mrs2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
membrane	LOCATE Predicted Protein Localization Annotations	1.0	null
POLR2A_K562_hg19_9	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-P4QS-1326-SM-3NMCD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.82392
BRD-K29850806	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07011
Perturb_6169_KD_PROX1_SRP073100	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-4.84088
GSE169697,GSE169725_1_v_4_prrx1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
NOLC1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00381139
Astrocytoma_CNS - Brain (MMHCC)_GSE4290	GEO Signatures of Differentially Expressed Genes for Diseases	1.0	1.53922
regulation of transmembrane transport	GO Biological Process Annotations 2015	1.0	null
GTEX-OOBJ-0006-SM-2I3F4	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.17991
Skin Cutaneous Melanoma_SKCM_TCGA-DA-A1HY-06A-11R-A18T-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
biological regulation	GO Biological Process Annotations 2015	1.0	null
GTEX-WHSB-1826-SM-3TW8M	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.94311
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7102-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
RFC1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.23281
anterior (rostral) cingulate (medial prefrontal) cortex_21 pcw_F_12365	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	1.18684
GSE88819_3_v_8_tug1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE196117_1_v_0_clarithromycin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
GSE157383_0_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
SNUC5	CCLE Cell Line Gene CNV Profiles	-1.0	-3.2099
NFYA_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7008-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K35108166	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.78243
BRD-K63030320	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08838
NFYC	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	22.7016
H3K4me3_H7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
DE-62-FI29_10uM	NIBR DRUG-seq U2OS MoA Box Gene Expression Profiles	1.0	0.298968
E2F6_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE238005_5_v_3_c9orf72_human	RummaGEO Gene Perturbation Signatures	-1.0	null
NSC-625987	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.39148
GTEX-S4P3-0426-SM-4AD56	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.860957
GSE121319_1_v_2_gprc5a_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-P4PP-0005-SM-2HMKX	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.71027
amygdaloid complex_37 pcw_M_263195015	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.901983
H3K4me3_Panc1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
TEAD4_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EZH2_skeletal muscle myoblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PWOO-0006-SM-2I3E3	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.31957
MAX	ENCODE Transcription Factor Targets	1.0	null
GSE171401_1_v_2_adnp_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Perturb_3236_KD_Ikaros_SRP067339	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.178
CTCF_fibroblast of mammary gland_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
estradiol_homo sapiens_gpl570_gds3217	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BRD-K75842461	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.96755
BRD-K55487965_NCGC00182364-01_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
K562_Momelotinib_1然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0179256
GSE238018_1_v_0_mxra8_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Postsynaptic intermediate filament cytoskeleton	COMPARTMENTS Text-mining Protein Localization Evidence Scores 2025	1.0	1.586
A549_Glesatinib(MGCD265)_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0125177
TCF12_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K05123945	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31625
MCF7_Divalproex Sodium_100nM_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0141577
EP300	ENCODE Transcription Factor Targets	1.0	null
GSE180185_9_v_8_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
Flocculus, molecular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.42169
Kidney renal papillary cell carcinoma_KIRP_TCGA-HE-7129-01A-11R-1965-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
SKM-1	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-3.37924
inferolateral temporal cortex (area TEv, area 20)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.02748
POLR2AphosphoS5_neural cell_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
SNU466	CCLE Cell Line Gene CNV Profiles	1.0	1.50069
A101D	COSMIC Cell Line Gene CNV Profiles	1.0	2.09117
AGER	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00685301
GSE210101,GSE210114_6_v_9_urod_human	RummaGEO Gene Perturbation Signatures	1.0	null
KCNK15	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00389525
POP5	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.22866
CTCF_GM13976_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HS 38.T	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	0.918645
GSE255432_7_v_2_imeglimin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
GSE48812_0_v_1_sulforaphane_human	RummaGEO Drug Perturbation Signatures	-1.0	null
YY1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE132386_2_v_0_ppara_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K30865566	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.23244
GSE155031_5_v_1_dextran_human	RummaGEO Drug Perturbation Signatures	-1.0	null
PMC4856960-supp_gkv1471_nar-01762-z-2015-File012.xlsx-GO_common_7H-HIF1_chip-Common_elements_in_chip7h_and_chip_hif1_2530_official_gene_symbols_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
C2BBE1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.49859
PMC8065135-41467_2021_22068_MOESM6_ESM.xlsx-E_MYOG_binding_in_downreg-Unnamed_1_MYOG	Rummagene Transcription Factor Associations 2026	1.0	null
GSE199899_3_v_0_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Msgn1	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	15.1661
REST_Panc1_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NCI-H292	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
nucleus of the diagonal band, left, horizontal division	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.0863
MAX	JASPAR Predicted Transcription Factor Targets	1.0	null
CRCGN015_HEPG2_48H:C22	Carcinogenome Chemical Perturbation Carcinogenicity Signatures	-1.0	-3.33422
hsa-miR-362-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.965816
MCF7_Alendronate sodium trihydrate_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.0192378
GSE148193_1_v_0_satb2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE129858,GSE129859_1_v_3_robo1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_GM12864_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Crus I, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.11174
SNU668	CCLE Cell Line Gene CNV Profiles	-1.0	-1.96762
BRD-K79222491_2-morpholino-9-(thiophen-3-yl)-N-((5-(trifluoromethyl)-1H-benzo[d]imidazol-2-yl)methyl)-9H-purin-6-amine_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE125219,GSE125221_5_v_0_arid1a_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CEBPB_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE228181_3_v_5_idh1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
MAFK_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE210225_0_v_1_uba6_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
VZ in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-2.29192
Perturb_8912_KO_NUDT21_SRP323081	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	1.0	6.42912
ZBTB7A	ENCODE Transcription Factor Targets	1.0	null
Acute Myeloid Leukemia_LAML_TCGA-AB-3006-03A-01T-0736-13	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Vitamin K4_Hs 766T	Tahoe Therapeutics Tahoe 100M Perturbation Atlas	1.0	0.00481031
Kidney renal clear cell carcinoma_KIRC_TCGA-BP-4768-01A-01R-1289-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K83586473	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.08431
GTEX-OHPK-1326-SM-3MJGN	GTEx Tissue Sample Gene Expression Profiles	1.0	1.5246
Digestive gland	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
RENBP	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00601636
dorsal thalamus_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.23385
GSE182185_0_v_1_pstk_human	RummaGEO Gene Perturbation Signatures	-1.0	null
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc124_7day-MOI-10^3_None_GSE44445	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.31611
positive regulation of establishment of protein localization	GO Biological Process Annotations 2025	1.0	null
H3K79me2_myocyte_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
ESR1-26153859-MCF-7-HUMAN-BREASTCANCER	ChEA Transcription Factor Targets 2022	1.0	null
GTEX-T6MN-0011-R5A-SM-32QPD	GTEx Tissue Sample Gene Expression Profiles	1.0	1.58181
H3K4me1_placenta_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
PMC9377669-tx1c00392_si_002.xlsx-Lithium_Chloride-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
TMSB4X	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.32815
BRD-K18190982_COT-10b_VCAP_6.0_h_44.4_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
EGR1_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE209582_1_v_0_chloroquine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SF3B4	Pathway Commons Protein-Protein Interactions	1.0	null
GTEX-XUZC-0005-SM-4BOQ8	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.74747
pituitary	GTEx Tissue Gene Expression Profiles	1.0	1.01053
Cellular anatomical entity	COMPARTMENTS Curated Protein Localization Evidence Scores 2025	1.0	5.0
Entorhinal area, lateral part, layer 3	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13037
BRD-K09376957	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.14702
H3K4me3_megakaryocyte_mm9_3	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K68407802_KIN001-055_PC3_24_h_1.11_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
BACH1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC12542114-12964_2025_2459_MOESM4_ESM.xlsx-DMOG_-_HIF1A-gene_HIF1A	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-A58937872	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.32941
GSE179880_7_v_5_e2f4_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
PHF8_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
REST	ENCODE Transcription Factor Targets	1.0	null
496100322_FWM_possible Alzheimer's disease_no TBI_100+_M	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.15849
hsa-miR-499a-3p	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.55165
GSE242333_0_v_3_sorafenib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
A704	CCLE Cell Line Gene CNV Profiles	1.0	2.72547
KP-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.983913
FOXA2_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
MAFF	ENCODE Transcription Factor Targets	1.0	null
RC-K8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.844358
primary auditory cortex (core)_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.64223
hsa-miR-488	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.20993
posterior (caudal) superior temporal cortex (area 22c)_13 pcw_M_12820	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	0.876342
Bladder Urothelial Carcinoma_BLCA_TCGA-GD-A3OQ-01A-32R-A220-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K87433679	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.04411
PMC10082046-41467_2023_37049_MOESM7_ESM.xlsx-Sheet1-Supplementary_Data_4_Genes_upregulated_in_ASPS-KY_cells_by_ASPSCR1-TFE3_knockdown_TFE3	Rummagene Transcription Factor Associations 2026	1.0	null
CAMA1	DepMap CRISPR Gene Dependency	1.0	3.01868
Perturb_13108_KO_Mbnl1/Mbnl2_SRP045573	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	18.4437
Bed nuclei of the stria terminalis, anterior division, juxtacapsular nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.31615
USF2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
estradiol_homo sapiens_gpl570_gse16683	GEO Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-QVUS-0011-R6A-SM-3GACX	GTEx Tissue Sample Gene Expression Profiles	1.0	1.18693
Kidney renal clear cell carcinoma_KIRC_TCGA-EU-5906-01A-11R-1672-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
superficial stratum of r4BM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.2592
GTEX-WVLH-0006-SM-3MJF7	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.81893
E2F1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE149769_1_v_0_nlrp12_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE104022_3_v_4_tamoxifen_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
temporal neocortex_9 pcw_M_12833	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.02736
quinisocaine-2151	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
TICRR	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.55802
RCOR1	ENCODE Transcription Factor Targets	1.0	null
H3K4me3_fibroblast of mammary gland_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
RKO	DepMap CRISPR Gene Dependency	1.0	3.49454
GSE77108_3_v_1_saha_human	RummaGEO Drug Perturbation Signatures	1.0	null
SU8686	DepMap CRISPR Gene Dependency	1.0	2.24269
GTEX-T5JC-0011-R5A-SM-32PLK	GTEx Tissue Sample Gene Expression Profiles	1.0	1.56253
GSE182680,GSE182683_0_v_3_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K07736136_S6005_A549_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
MXI1_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE180185_4_v_10_setbp1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K78122587_NNC 55-0396 dihydrochloride_HCC515_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
Perturb_9072_KD_SEPTIN2_SRP288211	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-5.15015
PMC4729482-pone.0146505.s001.xlsx-Sheet1-pRCC_positively_associated_with_AR_AR	Rummagene Transcription Factor Associations 2026	1.0	null
Liver hepatocellular carcinoma_LIHC_TCGA-DD-A1EC-01A-21R-A131-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Nucleus of the trapezoid body	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.6563
striatum_1 yrs_F_12830	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.36358
SAP30_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
EGR1_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Prostate adenocarcinoma_PRAD_TCGA-EJ-7785-01A-11R-2118-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_HCT116_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
inferolateral temporal cortex (area TEv, area 20)_24 pcw_M_12288	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	1.0	0.95291
GTEX-Q2AG-0011-R6A-SM-2HML7	GTEx Tissue Sample Gene Expression Profiles	1.0	1.53084
molecular_function	GO Molecular Function Annotations 2015	1.0	null
Declive (VI), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.79678
H2AFZ_fibroblast of lung_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE151090_2_v_4_verteporfin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE196835_0_v_1_ddx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
POLR2A_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-V955-0126-SM-4JBH5	GTEx Tissue Sample Gene Expression Profiles	1.0	1.20443
PBX3_SK-N-SH_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K52551495	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.3342
primary motor cortex (area M1, area 4)_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-0.875011
Pheochromocytoma and Paraganglioma_PCPG_TCGA-SR-A6MX-06A-11R-A35L-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K93737936	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58105
BRD-K78217087	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.27066
Liver	GTEx Tissue Gene Expression Profiles 2023	1.0	1.87547
GSE178255_1_v_4_tlr4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE234637_3_v_0_cytarabine_human	RummaGEO Drug Perturbation Signatures	1.0	null
H2AC17	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.043
GTEX-OXRP-0006-SM-2I3FN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-4.07952
Lung squamous cell carcinoma_LUSC_TCGA-43-6143-01A-11R-1820-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K42663584	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.25102
289_AMD1_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.502564
GSE197257_0_v_1_gpd2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
CTCF_GM13977_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PPP5C	Pathway Commons Protein-Protein Interactions	1.0	null
POLR2AphosphoS5_Panc1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE179880_10_v_6_e2f4_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-R45C-0006-SM-3GAD6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.15154
Liver hepatocellular carcinoma_LIHC_TCGA-5C-A9VG-01A-11R-A37K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
dentate gyrus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	2.44393
HCC1500	CCLE Cell Line Gene CNV Profiles	1.0	1.45707
GTEX-QDVJ-0726-SM-48U1W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.838158
BRD-A09719808_NCGC00188536-01_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GTEX-SUCS-0526-SM-4DM56	GTEx Tissue Sample Gene Expression Profiles	1.0	1.35777
GSE132948,GSE132949_2_v_3_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
sin3a_22783022_mcf7_lof_human_gpl570_gds4388	GEO Signatures of Differentially Expressed Genes for Transcription Factor Perturbations	-1.0	-0.062659
tuberal nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.67579
C3	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00625148
GSE202284,GSE202289_3_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MN-0011-R6A-SM-32QP8	GTEx Tissue Sample Gene Expression Profiles	1.0	2.21812
Perturb_1437_KO_Kmt2c_SRP283007	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	1.0	5.25551
GSE135352_6_v_4_napabucasin_human	RummaGEO Drug Perturbation Signatures	1.0	null
CTCF_fibroblast of upper leg skin_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55E-0011-R7A-SM-2TC5Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.977674
A-Vietnam-1203_CIP048_RG4-2004(H5N1)NS1trunc_3Hour_None_GSE43204	GEO Signatures of Differentially Expressed Genes for Viral Infections	1.0	2.70758
Perturb_17183_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
Lung adenocarcinoma_LUAD_TCGA-44-6146-01A-11R-1755-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
ARHGAP9	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00389611
BRD-K00507184	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.3964
posteroventral (inferior) parietal cortex_8 yrs_M_12841	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.45614
Cerebellar cortex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.20982
CTCF_mammary epithelial cell_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Striatum-like amygdalar nuclei	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.2185
GM1600	BioGPS Cell Line Gene Expression Profiles	1.0	0.998648
OCI-M1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.29608
cyclosporine_homo sapiens_gpl570_gse15935	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H2BK20ac_H9	Roadmap Epigenomics Histone Modification Site Profiles	1.0	null
PMC11655728-12672_2024_1562_MOESM2_ESM.xlsx-Sheet1-Hs_ESC_NANOG_targets_Boyer_NANOG	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-U3ZH-0005-SM-3DB72	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.23937
H3K4me1_heart_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
Kidney renal clear cell carcinoma_KIRC_TCGA-CW-5588-01A-01R-1541-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
laterodorsal subdivision of area 8	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.19962
GSE133329_2_v_3_trim28_human	RummaGEO Gene Perturbation Signatures	-1.0	null
CAL51	DepMap CRISPR Gene Dependency	1.0	5.13798
1716_CNOT1_P1P2	Replogle et al., Cell, 2022 RPE1 Essential Perturb-seq Gene Perturbation Signatures	1.0	1.02156
ES-WA7 Cells	Roadmap Epigenomics Cell and Tissue DNA Methylation Profiles	-1.0	-1.7398
GSE199899_3_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
DLX6	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	14.169
GTEX-Y8E5-0006-SM-47JWQ	GTEx Tissue Sample Gene Expression Profiles	-1.0	-2.10852
LIVF001-005	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.49687
posterior hypothalamic area, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.15215
NFIC::TLX1	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	28.0
GTEX-WHSE-0011-R8A-SM-3P5Z1	GTEx Tissue Sample Gene Expression Profiles	1.0	0.86459
BRD-K48827674	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.50095
inner CP in lateral temporal-occipital cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.15294
RAD21_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE132948,GSE132949_0_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me3_NB4_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K27ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A75409952_wortmannin_VCAP_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GTEX-N7MS-0011-R6a-SM-2HMJ4	GTEx Tissue Sample Gene Expression Profiles	1.0	1.98587
NOXO1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00483077
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEP3_UP_AA_UP-AA_UP_TEAD1	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K52911425_GDC-0941_HME1_3_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE95688_7_v_2_glutathione_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_K562_hg19_4	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-Q2AG-0011-R10A-SM-2HMLA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.917646
GABBR2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00523824
GSE182680,GSE182683_5_v_1_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
GRANTA-519	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.979395
CTCF_epithelial cell of esophagus_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CEBPD	ENCODE Transcription Factor Targets	1.0	null
BRD-K81418486_vorinostat_NEU_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE198165,GSE198166_7_v_4_zfp266_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_HepG2_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
9328_TRRAP_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.501684
GSE142210_9_v_0_panobinostat_human	RummaGEO Drug Perturbation Signatures	-1.0	null
MAX_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CHD1_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bladder Urothelial Carcinoma_BLCA_TCGA-DK-A3X2-01A-11R-A22U-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
YY1_HCT116_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-R55F-0005-SM-2TF4W	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.46869
Inferior olivary complex	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-3.19317
striatum_21 pcw_M_12886	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	1.0	1.62025
GSE211357_1_v_3_atg7_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE182680,GSE182683_0_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
BRD-K59778279	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.31162
BRD-K17910820	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.1895
GSE211474,GSE212779_8_v_4_phf8_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Metencephalon	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.236
primary auditory cortex (core)_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.875494
H3K4me3_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-VJYA-0005-SM-3P5ZD	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.47914
GSE174418,GSE174421_2_v_3_mettl5_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
POLR2A_HEK293_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE245778_1_v_0_runx1_human	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-RU72-0011-R8A-SM-2TF61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.02364
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.961868
VI, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.3562
LN-18	COSMIC Cell Line Gene Mutation Profiles	1.0	null
GSE127790_9_v_3_zcchc8_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
CHD1_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE226249_2_v_8_pirfenidone_human	RummaGEO Drug Perturbation Signatures	1.0	null
trp	GeneRIF Biological Term Annotations	1.0	null
HDAC2_H1-hESC_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PVOW-0011-R1A-SM-32PL6	GTEx Tissue Sample Gene Expression Profiles	1.0	0.94683
MARCKS	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00467092
POLR2A_K562_hg19_8	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-WL46-3026-SM-3LK7Z	GTEx Tissue Sample Gene Expression Profiles	1.0	0.909712
etamivan-1730	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_fibroblast of lung_hg19_7	ENCODE Histone Modification Site Profiles	1.0	null
cyclocytidine	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.56625
GSE123638,GSE123639_3_v_1_bortezomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE202434,GSE202438_12_v_14_talazoparib_human	RummaGEO Drug Perturbation Signatures	1.0	null
periventricular stratum of PalSe	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.22695
naproxen-1828	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE184892_7_v_3_trehalose_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE202284,GSE202289_7_v_4_bmal1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
KELLY	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.04113
GSE225869_1_v_0_cd44_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K92541860	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.412
H3K27ac_HCT116_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-UPIC-0005-SM-3GACV	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.52893
BRD-K26818574_-666_HT29_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE118548_1_v_3_trametinib_human	RummaGEO Drug Perturbation Signatures	1.0	null
A_CA_04_2009_7dayMOI-10^6_None_GSE37569	GEO Signatures of Differentially Expressed Genes for Viral Infections	-1.0	-2.35964
Occipital lobe	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.575
BRD-A63949900_NCGC00238536-01_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
H3K4me3_cardiac mesoderm_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE195559_8_v_7_notch1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE239688_2_v_3_canagliflozin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-RU72-0006-SM-2TF65	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.19294
H3K27ac_K562_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
TCF7L2_HeLa-S3_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HIPK2_defectivemutant_17_GDS1793	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	1.0	1.49861
GTEX-X4XX-0011-R10B-SM-46MWO	GTEx Tissue Sample Gene Expression Profiles	1.0	1.15026
Blastema	TISSUES Text-mining Tissue Protein Expression Evidence Scores 2025	1.0	0.807
EP300_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-A49765801_-666_A375_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
BRD-K68890376	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.31978
eGFP-GATA2_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_skin fibroblast_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRCA1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
amphetamine_rattus norvegicus_gpl6101_gse31081	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
LRP2	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00557823
GSE239844_7_v_5_crizotinib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Male reproductive system disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.123
BRD-K64577478	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.01742
GSE216043_11_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
GTEX-Q2AH-0826-SM-48TZN	GTEx Tissue Sample Gene Expression Profiles	-1.0	-0.831814
CSNK1G1	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00608991
GSE88819_6_v_9_tug1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE229468,GSE229471_2_v_1_znf587_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K11696817	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.77083
ZNF280A	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.47461
periventricular mantle of isBM	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.16948
Internal female genital organ	TISSUES Curated Tissue Protein Expression Evidence Scores 2025	1.0	4.0
central portion of GPi	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.16117
CALU	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	-1.0	-0.00671957
AOB, granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.24382
COLO 201	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-0.975285
A549_SL-327_10然_24h	Sci-Plex Drug Perturbation Signatures	1.0	0.010883
GSE158431_5_v_7_pioglitazone_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_17177_OE_HER2_SRP166112	PerturbAtlas Signatures of Differentially Expressed Genes for Gene Perturbations	-1.0	-20.0
GTEX-QDT8-0011-R3A-SM-32PKR	GTEx Tissue Sample Gene Expression Profiles	1.0	0.836643
COLO 680N	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898719
RFX5	ENCODE Transcription Factor Targets	1.0	null
PMC10592962-media-4.xlsx-OC2_genes-gene_ONECUT2	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me1_CD14-positive monocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
hsa-miR-4310	TargetScan Predicted Conserved microRNA Targets	1.0	0.670641
GSE217452_2_v_1_docetaxel_human	RummaGEO Drug Perturbation Signatures	1.0	null
CREB1	ENCODE Transcription Factor Targets	1.0	null
septopallidal core nucleus	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.94886
Lung adenocarcinoma_LUAD_TCGA-69-A59K-01A-11R-A262-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS2_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_CD14-positive monocyte_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE148263_6_v_9_trim3_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-XBED-0006-SM-47JXO	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.51048
oxaliplatin	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.26671
BRCA1	ENCODE Transcription Factor Targets	1.0	null
PML_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE147876,GSE147877_4_v_10_enzalutamide_human	RummaGEO Drug Perturbation Signatures	1.0	null
GSE95077_1_v_2_amiloride_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SF3B6	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.0793
KAT2B	ENCODE Transcription Factor Targets	1.0	null
GTEX-XOTO-0011-R6B-SM-4B65X	GTEx Tissue Sample Gene Expression Profiles	1.0	0.841074
GSE210580_4_v_12_rag2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K72278003	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.24809
SG in midlateral temporal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.28451
GSE178340_7_v_3_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
HEATR1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.1426
TBP_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE89018_10_v_8_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE164874_5_v_12_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
NKX1-2	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.09525
PMC9377669-tx1c00392_si_002.xlsx-Favipiravir-ZNF503_ZNF503	Rummagene Transcription Factor Associations 2026	1.0	null
BRD-K33495825	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.58699
Brain Lower Grade Glioma_LGG_TCGA-HT-7475-01A-11R-2027-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
GSE136894_2_v_3_psen1_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE199899_1_v_2_diethylnitrosamine_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
PMC7782698-41467_2020_20367_MOESM9_ESM.xlsx-Student_s_t-test_BP1_ILK_GFP-Gene_names_DLX4	Rummagene Transcription Factor Associations 2026	1.0	null
NCI H322M	BioGPS Cell Line Gene Expression Profiles	-1.0	-1.46226
GSE111660_4_v_6_prdm16_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GSE158969_1_v_2_trastuzumab_human	RummaGEO Drug Perturbation Signatures	1.0	null
BRD-K30201819	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.42347
EP300_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me2_T-cell acute lymphoblastic leukemia_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
MDAMB361	Heiser et al., PNAS, 2011 Cell Line Gene Expression Profiles	1.0	0.731074
BRD-K54850621	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-4.15217
placenta_6b	HPA Tissue Sample Gene Expression Profiles	1.0	1.08034
Primary somatosensory area, mouth, layer 1	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-2.14374
5016_MFAP1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.516703
tail of caudate nucleus, left	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	1.0	1.44743
ZNF8	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	31.2613
placenta	HPA Tissue Gene Expression Profiles	1.0	1.42498
T84	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.19205
ZMIZ1	ENCODE Transcription Factor Targets	1.0	null
USP4	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00553976
GSE157383_6_v_1_abemaciclib_human	RummaGEO Drug Perturbation Signatures	1.0	null
chlorhexidine-2025	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
YY1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC8190596-mmc2.xlsx-ETV6_mut-ETV6_mut_ETV6	Rummagene Transcription Factor Associations 2026	1.0	null
H3K4me3_GM12864_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
GTEX-QDVJ-1126-SM-48U1U	GTEx Tissue Sample Gene Expression Profiles	1.0	0.91436
PMC10592471-NIHMS1912771-supplement-4.xlsx-D-HEp3_UP_NR2F1_ind_UP-NR2F1_Ind_UP_NR2F1	Rummagene Transcription Factor Associations 2026	1.0	null
GSE213442_1_v_0_kpna2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-NPJ7-0006-SM-3GACR	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.13761
GTEX-RU72-3126-SM-46MUB	GTEx Tissue Sample Gene Expression Profiles	1.0	0.941934
OAW28	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
REST_K562_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE158632_3_v_0_oxyquinoline_human	RummaGEO Drug Perturbation Signatures	-1.0	null
POLR2AphosphoS5_endothelial cell of umbilical vein_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-Q2AG-0011-R5A-SM-2HMJH	GTEx Tissue Sample Gene Expression Profiles	1.0	1.33869
frontalcortex	BioGPS Mouse Cell Type and Tissue Gene Expression Profiles	1.0	0.883717
POU5F1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.79595
H3K4me3_cardiac mesoderm_hg19_6	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K72336314	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.30129
Brain - Amygdala	GTEx Tissue Gene Expression Profiles 2023	-1.0	-0.96145
GSE164874_5_v_2_prednisolone_human	RummaGEO Drug Perturbation Signatures	-1.0	null
Perturb_1618_KO_Cebpb_SRP056432	PerturbAtlas Signatures of Differentially Expressed Genes for Mouse Gene Perturbations	-1.0	-3.14975
CTCF_HCT116_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
VIIB, right, paravermis	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.20145
ELF1_GM12878_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
positive regulation of molecular function	GO Biological Process Annotations 2015	1.0	null
GSE211128_2_v_1_angptl4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K53281329_SYK-inhibitor_MCF7_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE217105_0_v_1_gemcitabine_mouse	RummaGEO Drug Perturbation Signatures	-1.0	null
TAF1_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CTCF_foreskin fibroblast_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
RXRA	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.00545665
SP in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.09601
5557_NDUFB5_P1P2	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	1.0	0.544033
GSE149096_4_v_3_ascl1_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GTEX-WHSE-0011-R6A-SM-3P5ZP	GTEx Tissue Sample Gene Expression Profiles	1.0	1.46517
hsa-miR-520d-5p	TargetScan Predicted Conserved microRNA Targets	1.0	0.136254
Ebf2	JASPAR Predicted Mouse Transcription Factor Targets 2025	1.0	26.3004
RAMOS	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.95802
island of Calleja major	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.13792
mediodorsal nucleus of thalamus_2 yrs_F_12979	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-1.0559
BRD-K19579217	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.29947
HCFC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE119978,GSE180930_6_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GTEX-S7SF-0006-SM-3K2B6	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.1807
PHOX2B-30127528-KELLY-HUMAN-BRAINNEUROBLASTOMA	ChEA Transcription Factor Targets 2022	1.0	null
PMC11046918-12967_2024_5211_MOESM4_ESM.xlsx-F_HT1080_FUS-DDIT3_regulated-Table_S2_Regulated_genes_between_scaffold-cultured_and_monolayer-cultured_cells_DDIT3	Rummagene Transcription Factor Associations 2026	1.0	null
valproic acid_homo sapiens_gpl6883_gse26940	GEO Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K4me3_small intestine_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
GSE225982_2_v_0_ezetimibe_human	RummaGEO Drug Perturbation Signatures	-1.0	null
496100543_FWM_probable Alzheimer's disease_TBI_78_F	Allen Brain Atlas Aging Dementia and Traumatic Brain Injury Tissue Sample Gene Expression Profiles	-1.0	-2.05434
regulation of cell migration	GO Biological Process Annotations 2015	1.0	null
GSE89018_12_v_2_cry2_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
AFF1	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	1.0	2.30355
H3K4me3_BE2C_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
BRD-A52893269	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.56308
BRD-A45333398_PERIPLOCYMARIN_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
hsa-miR-607	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.809003
FGFR1_mutant_26_GDS4046	GEO Signatures of Differentially Expressed Genes for Kinase Perturbations	-1.0	-1.06458
H3K4me3_HEK293_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
H3K4me3_limb_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
CREB1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
YY1_ECC-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
CACYBP	Pathway Commons Protein-Protein Interactions	1.0	null
Purkinje cell layer of CbVCx	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.05278
carmustine-6914	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
POLR2A_HeLa-S3_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
FOS	ENCODE Transcription Factor Targets	1.0	null
TCF12_ECC-1_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_HepG2_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE119978,GSE180930_0_v_7_cisplatin_human	RummaGEO Drug Perturbation Signatures	1.0	null
3823_HMG20B_P1	Replogle et al., Cell, 2022 K562 Genome-wide Perturb-seq Gene Perturbation Signatures	-1.0	-0.526062
cuneate nucleus, right	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.12927
hsa-miR-539	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.880544
JHH-7	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.05261
GSE168596_2_v_3_adiponectin_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Pheochromocytoma and Paraganglioma_PCPG_TCGA-QT-A5XJ-01A-11R-A35K-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
H3K4me3_BJ_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
SMC3	ENCODE Transcription Factor Targets	1.0	null
BRD-K02708799_GSK-1059615_HA1E_24_h_0.37_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
H3K9ac_astrocyte_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
SK-N-SH	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.39746
COLO320_LARGE_INTESTINE	CCLE Cell Line Proteomics	1.0	4.86914
RMG-I	Sanger Dependency Map Cancer Cell Line Proteomics	-1.0	-4.01561
amygdaloid complex_4 yrs_M_12298	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.858992
GSE216043_10_v_8_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
GSE217132_0_v_1_pfkfb4_human	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-A69512159_carbidopa_MCF7_6.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE125014_6_v_3_enzalutamide_human	RummaGEO Drug Perturbation Signatures	-1.0	null
CHD2_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
K562_Capecitabine_10然_24h	Sci-Plex Drug Perturbation Signatures	-1.0	-0.0143704
GTEX-Q2AG-0011-R4A-SM-2HMKA	GTEx Tissue Sample Gene Expression Profiles	1.0	0.847516
GTEX-N7MS-0011-R10A-SM-2HMJK	GTEx Tissue Sample Gene Expression Profiles	1.0	0.884593
RAD21_MCF-7_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
negative regulation of biological process	GO Biological Process Annotations 2015	1.0	null
H3K27me3_megakaryocyte_mm9_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ETS2	ChEA Transcription Factor Targets	1.0	null
NCI-H740	COSMIC Cell Line Gene Mutation Profiles	1.0	null
CTCF_A549_hg19_5	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Bed nuclei of the stria terminalis, anterior division, anterolateral area	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	2.23564
GTEX-PWCY-0226-SM-48TD8	GTEx Tissue Sample Gene Expression Profiles	1.0	1.23551
BRD-K42061172	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.62755
GSE207514,GSE207515_0_v_3_acetylcysteine_human	RummaGEO Drug Perturbation Signatures	-1.0	null
dorsolateral prefrontal cortex_4 mos_M_12889	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by RNA-seq	-1.0	-0.970362
GTEX-S32W-0126-SM-4AD61	GTEx Tissue Sample Gene Expression Profiles	1.0	1.34842
GSE201042_2_v_4_ptpmt1_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K70594121	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.10159
hsa-miR-4436b-5p	TargetScan Predicted Nonconserved microRNA Targets	1.0	0.921135
GSE231648_0_v_2_lsm14b_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-U412-0006-SM-3DB8J	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.29046
BRD-K06792661_Narciclasine_A375_24.0_h_10.0_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	-1.0	null
GSE184210_0_v_3_glucagon_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
Brain Lower Grade Glioma_LGG_TCGA-DU-7309-01A-11R-2090-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
POLR2AphosphoS5_PFSK-1_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
TAF1_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-PLZ6-0226-SM-3P61I	GTEx Tissue Sample Gene Expression Profiles	1.0	0.839538
positive regulation of ion transmembrane transport	GO Biological Process Annotations 2015	1.0	null
SOX2-18692474-MESC-mouse	ChEA Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_WERI-Rb-1_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BHLHE40_HepG2_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE196540,GSE196542_4_v_0_dnmt3a_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
inner SZ in dorsomedial frontal cortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.0639
H4K20me1_myotube_hg19_1	ENCODE Histone Modification Site Profiles	1.0	null
Disease	DISEASES Text-mining Gene-Disease Association Evidence Scores 2025	1.0	1.131
A549_Tazemetostat_1然_72h	Sci-Plex Drug Perturbation Signatures	1.0	0.0145247
CTCF_GM06990_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K92701606	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.06005
GSE193993_5_v_7_sstr2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
TCF7	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	17.2522
GTEX-XUYS-0005-SM-47JZ2	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.04273
YY1_GM12878_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
NUDC	Pathway Commons Protein-Protein Interactions	1.0	null
TAF1_HeLa-S3_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
HDAC1_K562_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
ventricular (matrix) zone of pons	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.6279
ovary_6a	HPA Tissue Sample Gene Expression Profiles	1.0	0.882608
NP8	DepMap CRISPR Gene Dependency	1.0	2.3059
Fetalbrain	BioGPS Human Cell Type and Tissue Gene Expression Profiles	1.0	1.49132
MDST8	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Mutation Profiles	1.0	null
head of caudate	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.837395
GTEX-T5JC-0011-R8A-SM-32PLM	GTEx Tissue Sample Gene Expression Profiles	1.0	1.30973
GSE182680,GSE182683_10_v_8_dexamethasone_human	RummaGEO Drug Perturbation Signatures	1.0	null
olfactory tubercle	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	1.37895
hsa-miR-548y	TargetScan Predicted Conserved microRNA Targets	1.0	0.828473
GSE119978,GSE180930_3_v_5_cisplatin_human	RummaGEO Drug Perturbation Signatures	-1.0	null
SOX21	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	38.3663
1839_CPSF1_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.819609
motor nucleus of trigeminal nerve	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	1.0	0.879756
EP300_HepG2_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
hsa-miR-4427	TargetScan Predicted Nonconserved microRNA Targets	1.0	1.2992
PMC10641274-mmc2.xlsx-FOXK1_Insulin-ENSEMBL_FOXK1	Rummagene Transcription Factor Associations 2026	1.0	null
GTEX-X62O-0005-SM-46MV1	GTEx Tissue Sample Gene Expression Profiles	-1.0	-1.07134
layer 6 of PrS	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.91024
Cancer of thyroid_Thyroid_GSE5364	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.5248
Lung squamous cell carcinoma_LUSC_TCGA-58-8386-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-M07851152	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.03751
BRD-K28399883	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.07037
GSE236262_2_v_1_trim28_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
H3K4me2_A549_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE98705_1_v_0_mdm2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
BRD-K00423214	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.2577
CTCF_Caco-2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GTEX-XLM4-3026-SM-4AT6L	GTEx Tissue Sample Gene Expression Profiles	1.0	0.851942
KMS-21BM	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-2.17639
GSE118939_1_v_0_nras_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K32943057	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.59496
GOPC	CM4AI KOLF21J CRISPRi Gene Perturbation Atlas	-1.0	-2.63298
sulindac-1815	CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
ventrolateral prefrontal cortex_18 yrs_M_12984	Allen Brain Atlas Developing Human Brain Tissue Gene Expression Profiles by Microarray	-1.0	-1.69913
POLR2AphosphoS5_SK-N-SH_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GMPPB	LINCS L1000 CMAP CRISPR Knockout Consensus Signatures	1.0	0.0064837
UNCX	JASPAR Predicted Human Transcription Factor Targets 2025	1.0	13.5823
H3K4me3_spleen_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
BRD-K45589340	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	-1.0	-3.02257
CAR-1	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-0.898719
GSE164757,GSE164759_1_v_3_trametinib_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
H3K4me3_MCF-7_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
POLR2A_K562_hg19_3	ENCODE Transcription Factor Binding Site Profiles	1.0	null
H3K4me3_K562_hg19_2	ENCODE Histone Modification Site Profiles	1.0	null
GSE207582_4_v_3_testosterone_mouse	RummaGEO Drug Perturbation Signatures	1.0	null
431_AQR_P1P2	Replogle et al., Cell, 2022 K562 Essential Perturb-seq Gene Perturbation Signatures	1.0	0.555129
A704	COSMIC Cell Line Gene CNV Profiles	1.0	2.09117
H3K4me1_lung_mm9_1	ENCODE Histone Modification Site Profiles	1.0	null
FARAGE	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	-1.0	-1.3038
JHH-5	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene Expression Profiles	1.0	1.79978
EP300_GM12878_hg19_4	ENCODE Transcription Factor Binding Site Profiles	1.0	null
PMC11196642-41419_2024_6838_MOESM5_ESM.xlsx-Supplementary_Table_3-Supplementary_Table_3_Differentially_expressed_genes_in_RNA-seq_between_MCF7_SMAD4-KO_and_parental_groups_SMAD4	Rummagene Transcription Factor Associations 2026	1.0	null
Head and Neck squamous cell carcinoma_HNSC_TCGA-CV-7097-01A-11R-2016-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K70357895	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.13151
VI, right, lateral hemisphere	Allen Brain Atlas Adult Human Brain Tissue Gene Expression Profiles	-1.0	-1.09631
H3K4me3_endothelial cell of umbilical vein_hg19_3	ENCODE Histone Modification Site Profiles	1.0	null
GSE178340_7_v_6_carfilzomib_human	RummaGEO Drug Perturbation Signatures	-1.0	null
H3K27ac_heart_mm9_2	ENCODE Histone Modification Site Profiles	1.0	null
CTCF_A549_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K57732605	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.80789
CTCF_GM19239_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
POLR2A_H1-hESC_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
BRD-K68191783_ALW-II-38-3_PC3_24_h_10_um	LINCS L1000 CMAP Signatures of Differentially Expressed Genes for Small Molecules	1.0	null
GSE132948,GSE132949_2_v_5_msi2_mouse	RummaGEO Gene Perturbation Signatures	-1.0	null
Cardiac muscle	TISSUES Experimental Tissue Protein Expression Evidence Scores 2025	1.0	1.041
VZ in subgenual cingulate neocortex	Allen Brain Atlas Prenatal Human Brain Tissue Gene Expression Profiles	-1.0	-1.55263
GTEX-T6MN-0011-R11A-SM-32QOX	GTEx Tissue Sample Gene Expression Profiles	1.0	0.869906
GTEX-T2IS-0011-R3A-SM-32QPB	GTEx Tissue Sample Gene Expression Profiles	1.0	1.21477
CTCF_BJ_hg19_1	ENCODE Transcription Factor Binding Site Profiles	1.0	null
Lingula (I), granular layer	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	-1.0	-1.77452
Obesity_Muscle - Striated (Skeletal) (MMHCC)_GSE474	GEO Signatures of Differentially Expressed Genes for Diseases	-1.0	-2.03629
HCC1806	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	-1.0	-1.83294
Lung squamous cell carcinoma_LUSC_TCGA-56-8307-01A-11R-2296-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
Sarcoma_SARC_TCGA-SI-A71Q-01A-12R-A33J-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
HNF4A_HepG2_hg19_2	ENCODE Transcription Factor Binding Site Profiles	1.0	null
GSE254649_3_v_0_cstf2_human	RummaGEO Gene Perturbation Signatures	-1.0	null
GSE113734_1_v_0_qprt_human	RummaGEO Gene Perturbation Signatures	1.0	null
BRD-K36324810	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	4.38013
GSE183413_0_v_2_ash1l_mouse	RummaGEO Gene Perturbation Signatures	1.0	null
GTEX-T6MN-0011-R1A-SM-32QOY	GTEx Tissue Sample Gene Expression Profiles	1.0	1.03524
Gustatory areas, layer 6b	Allen Brain Atlas Adult Mouse Brain Tissue Gene Expression Profiles	1.0	1.02728
COLO-800	Sanger Dependency Map Cancer Cell Line Proteomics	1.0	4.12966
MT-3	Klijn et al., Nat. Biotechnol., 2015 Cell Line Gene CNV Profiles	1.0	0.844358
Lung adenocarcinoma_LUAD_TCGA-69-7978-01A-11R-2187-07	TCGA Signatures of Differentially Expressed Genes for Tumors	1.0	null
BRD-K85418917	LINCS L1000 CMAP Chemical Perturbation Consensus Signatures	1.0	3.35876